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Parasitology: Course 1

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PARASITOLOGY

Course 1
Parasitology

• science that analyses the relationships


between parasites and their hosts,
studying the phenomena that result from
these relationships
Parasitism
• biological association that requires
two factors
• host - organism that provides food
and shelter
• parasite - organism that uses the
conditions offered by the host
Parasites

• several systematic categories


• dimensions and structures that can
widely vary
• pathogens that can affect the health
of humans and animals
Parasitology
• Protozoology

• Helminthology

• Medical entomology
Host

• the organism on whose account the


parasite lives
• Definitive host- sexual form of the
parasite
• Intermediate host- the intermediate
(larval) or asexual form of the parasite
in its biological cycle
Definitive host
Intermediate host
Parasitic life cycle

represents the stages that the parasite


undergoes through in its evolution

series of changes in form that an


organism undergoes, returning to the
starting state
One definitive host
Several definitive hosts
One intermediate host
Several intermediate hosts
Definitive host= Intermediate host
Parasite

• organism that can live on the surface


or inside another organism, of a
different species (host), and derive
the necessary nourishment from the
host
Classification
by the nature of the host

• Human parasites
• Parasites of animals
• Parasites of plants
• Parasites common to humans and
animals
Classification

• Protozoa
• Helminths
• Arthropods
Classification
by the effect on the host

• commensal (saprophytic)

• conditionally pathogenic

• Opportunistic

• Pathogenic
Classification
by the parasite localization in/ on the host

• ectoparasites

• endoparasites - cavitary

- tissue

- intracellular
Classification
by the length of stay

• temporary

• permanent
The characteristics of the parasitic
lifestyle
• host - mandatory condition for the existence
of parasites
• Living with the host
• Feed on living hosts
• Parasite - adaptation to the host
- leads to unfavorable effects on
host
Morphological adaptations of the
parasite
Body shape
Morphological adaptations of the
parasite
Size
Morphological adaptations of the
parasite
Internal and attaching organs
Progressive change
- hypertrophy -
Morphological adaptations of the
parasite
Internal and attaching organs
Progressive change
- neoformation -
Morphological adaptations of the
parasite
Internal and attaching organs
Progressive change
- atrophy -
Morphological adaptations of the
parasite
Internal and attaching organs
Progressive change
- disappearance -
The influence of parasite on the host

Plundering action
The influence of parasite on the host

Mechanical action
- obstruction -
The influence of parasite on the host

Mechanical action
- Tissue or organ compression -
The influence of parasite on the host

Mechanical action
- Trauma and perforation-
The influence of parasite on the host

Mechanical action
- local -
The influence of parasite on the host

Toxic action
- general -

• Diphyllobothrium latum - hemolytic toxin


• Ascaris lumbricoides - “ascaron” toxin
• Dermacentor andersoni – paralysing toxin
The influence of parasite on the host
Irritative action
- reflex -

• irritation of the intestinal mucosa


• irritation of the bile duct epithelium
• Chronic irritation of the skin and nasal/sinus mucosa
The influence of parasite on the host
Inflammatory action
• Ascaris lumbricoides and Enterobius vermicularis -
appendicitis
• Trichinella spiralis larvae - encystation
The influence of parasite on the host

Allergic reaction

• rupture of the hydatid cyst


The influence of parasite on the host

Bacterial action
Entry pathways used by the parasite

Passive way

• air
• water
• food
Entry pathways used by the parasite

Active way
Entry pathways used by the parasite

Consumption of the intermediate host


Entry pathways used by the parasite

Vectors
- contamination -
Entry pathways used by the parasite

Vectors
- inoculation -
Entry pathways used by the parasite

Blood transfusion
Entry pathways used by the parasite

Autoinfection

• Exogenous
• Endogenous
Entry pathways used by the parasite

Sexual
Entry pathways used by the parasite

Congenital
Ways of eliminating the parasite
Stool
Ways of eliminating the parasite

Saliva and Flügge's droplets


Vomica
Sputum
Urine
Vaginal and urethral secretion
Ways of eliminating the parasite

cutaneous
Ways of eliminating the parasite

detachment from the host's body


Ways of eliminating the parasite

through vectors
Population receptivity

• Population receptivity- mass of


individuals who, under certain living
and environmental conditions,
following the aggression of a pathogen,
become ill
Population receptivity
• Sex of the host
• Age
• Occupation
• Eating style
• Habits and traditions
• The immune status of the host
• Vaccinations and chemoprophylaxis
Eradication of parasitic diseases
Definition

actions applied to the links of the


epidemiological chain of a parasite, aiming at
the complete and definitive disappearance of
the cases of disease produced or transmitted
by the parasite in the territory where these
measures were taken
Eradication of parasitic diseases

Purpose

successfully reducing the number of cases of


the disease to a level where it ceases to be a
public or economic health problem
Eradication of parasitic diseases

Objective

reducing the parasitic population until


discontinuing the parasite life cycle
Eradication of parasitic diseases

Eradication program

• preparatory phase
• attack phase
• consolidation phase
• maintenance phase

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