MSC Orgchem Syllabus PVSL 2017 18 For Website PDF
MSC Orgchem Syllabus PVSL 2017 18 For Website PDF
MSC Orgchem Syllabus PVSL 2017 18 For Website PDF
M.Sc. CHEMISTRY
(Organic Chemistry)
DEPARTMENT OF CHEMISTRY
NATIONAL INSTITUTE OF TECHNOLOGY, WARANGAL-506 004
TELANGANA STATE, INDIA
2
M.Sc. CHEMISTRY
I SEMESTER
PROPOSED SCHEME OF INSTRUCTION
S. No Course Course Name Instruction Hrs Credits
Code L T P
1 CY5101 Fundamentals of Analytical Chemistry 4 0 0 4
2 CY5102 Main Group and Transition Metal Chemistry 4 0 0 4
3 CY5103 Reaction Mechanism and Stereochemistry 4 0 0 4
4 CY5104 Thermodynamics and Electrochemistry 4 0 0 4
5 CY5105 Inorganic Chemistry Laboratory 0 0 3 2
6 CY5106 Computational Chemistry Laboratory 0 0 3 2
7 CY5107 Organic Chemistry Laboratory – I 0 0 3 2
8 CY5108 Physical Chemistry Laboratory – I 0 0 3 2
Total Credits 24
II SEMESTER
PROPOSED SCHEME OF INSTRUCTION
S. No Course Course Name Instruction Hrs Credits
Code L T P
1 CY5151 Principles of Molecular Spectroscopy 4 0 0 4
2 CY5152 Solid State Chemistry and Group Theory 4 0 0 4
3 CY5153 Photochemistry and Pericyclic Reactions 4 0 0 4
4 CY5154 Chemical Kinetics and Quantum Chemistry 4 0 0 4
5 CY5155 Analytical Chemistry Laboratory 0 0 3 2
6 CY5156 Organic Chemistry Laboratory – II 0 0 3 2
7 CY5157 Physical Chemistry Laboratory – II 0 0 3 2
8 CY516X Elective - I* 3 0 0 3
9 CY5191 Seminar – I 0 2 0 1
Total Credits 26
*List of Courses for Elective-I : Elective-I shall be chosen by the students from the following list
M.Sc. CHEMISTRY
with Specialization in
ORGANIC CHEMISTRY
III SEMESTER
PROPOSED SCHEME OF INSTRUCTION
S. No. Course Course Name Instruction Credits
Code Hrs
L T P
1 CY6101 Organic Synthesis 4 0 0 4
2 CY6102 Organic Reagents and Name Reactions 4 0 0 4
3 CY6103 Organic Analysis Laboratory 0 0 6 4
4 CY6104 Organic Preparations Laboratory 0 0 6 4
5 CY611X Elective - II* 3 0 0 3
6 CY612X Elective - III* 3 0 0 3
7 CY6141 Seminar – II 0 2 0 1
Total Credits 23
*List of Courses for Electives-II and III: Electives-II and III shall be chosen by the students from the following list
M.Sc. CHEMISTRY
with Specialization in
ORGANIC CHEMISTRY
IV SEMESTER
PROPOSED SCHEME OF INSTRUCTION
S. Course Course Name Instruction Credits
No Code Hrs
L T P
1 CY6151 Stereoselective Synthesis 4 0 0 4
4 CY617X Elective - V* 3 0 0 3
Total Credits 21
*List of courses for Electives-IV, V and VI: Electives-IV, V and VI shall be chosen by the students from the following
list
M.Sc. CHEMISTRY
with Specialization in
ANALYTICAL CHEMISTRY
III SEMESTER
PROPOSED SCHEME of INSTRUCTION
S. No. Course Course Name Instruction Hrs Credits
Code L T P
1 CY6201 X-Ray and Microscopic Methods of Analysis 4 0 0 4
2 CY6202 Physical Methods of Chemical Analysis 4 0 0 4
3 CY6203 Instrumental Methods of Chem. Analysis Lab. - I 0 0 6 4
4 CY6204 Quantitative Chemical Analysis Laboratory 0 0 6 4
5 CY621X Elective – II* 3 0 0 3
6 CY612X Elective – III* 3 0 0 3
7 CY6241 Seminar 0 2 0 1
Total Credits 23
*List of Courses for Electives-II and III: Electives-II and III shall be chosen by the students from the following list
PROPOSED SYLLABUS
I SEMESTER
Text Books:
1. Quantitative Analysis, Day and Underwood, PHI, 6thEdn., 2009
2. Fundamentals of Analytical Chemistry,Skoog D.A,West D M, Holler, F J and Crouch S
R, Saunders College Publishing, 8thEdn., 2004.
3. Modern Analytical Chemistry, David Harvey, McGraw Hill, 2000.
Main group Chemistry: Structure and bonding in polyhedral boranes and carboranes, styx
notation; Wade’s rule; electron count in polyhedral boranes; synthesis of polyhedral boranes;
isolobal analogy; boron heterocycles; borazine. Silanes, silicates, silicones, silanols;
Isopoly&heteropoly acids, P-N compounds, structural features and reactivity of S-N
heterocycles. Synthesis and reactivity of organo-lithium, -beryllium and -magnesium
compounds; calixarines, cryptands and crown ethers in complexation chemistry. Preparation
and reactivity of aluminiumorganyls; carbalumination, hydroalumination.
Bio-inorganic Chemistry: Metal ions in Biological Systems; Metal Binding Biomolecules;
Metal Containing Units in Biology – Iron Sulfur Clusters, Poly-Iron-Oxo Clusters, Porphyrins,
Hydroporphyrins, Hemoglobin and Myoglobin; Electronic and Magnetic Aspects of Dioxygen
Binding; Oxygen Adsorption Isotherms and Co-operativity in Hemoglobin and Its
Physiological Significance; Chlorophyll – Photo System-I and-II; Metallo-Enzymes-
Nitrogenase, Catecholase, Peroxidase, Mutase Enzymes.
Text Books:
4. Inorganic Chemistry - Principles of Structures and reactivity, James E. Huheey, 3rdEdn., Harper
International Edition, New York, 1992.
5. Coordination Chemistry, D. Banerjee, Asian Books Private Ltd, 2 ndEdn.,2007.
6. Principles of Bioinorganic Chemistry, Stephen J. Lippard& Jeremy M. Berg, 2 ndEdn., Panima
Publishing Corporation, New Delhi, 2005.
7. An Introduction to Organometallic Chemistry, P.W. Parkins, R.C. Poller, Mac Milan Publishers,
1996.
8. Elements of Magnetochemistry, R.L. Datta and A. Syamal, S. Chand and Co. Ltd., 1982.
9. Concise Inorganic Chemistry, J.D. Lee, Blackwell Publishing, 5 th edition, 2006.
Reference Books:
1. Mechanism of Inorganic Reactions, F. Basalo and R. G. Pearson, WileyEastern Ltd., New
Delhi, 2ndEdn, 1967.
2. Inorganic Chemistry, D. F. Shriver and P. W. Atkins, ELBS, London, 3 rdEdn.,1999.
3. Advanced Inorganic Chemistry, F. A. Cotton and G. Wilkinson, John Wiley & Sons, New
York, 6thEdn.,1999.
4. Inorganic Chemistry, Keith F. Purcell and John C. Kotz, W. B. Sauders Com. HongKong,
1987.
5. Inorganic Reaction Mechanisms, Martin L. Tobe and John Burgess, Longmans 1 stEdn., 1999.
Code Reaction Mechanisms and Stereochemistry L T P C 56 hrs
CY5103 (Core) 4 - - 4
Structure and reactivity:
Nomenclature, General rules as applied to bicyclic compounds, spiro and heterospiro
compounds. Nature of reaction energy and kinetic considerations - types of organic reactions,
reactive intermediates: formation and stabilization, concept of tautomerism.
Nucleophilic Substitutions:
SN1, SN2, SN1i, SN2i, SNi, SNii internal return ion pair intermediates, solvent effects,
competition between SN1 and SN2 mechanism. Linear free energy relationships, Hammett
equation, Taft treatment of polar effects in aliphatic compounds. Neighboring group
participation of O, S, N, halogens, aryl groups, alkyl and cycloalkyl groups in nucleophilic
substitution reactions. Sigma, Pi bond participation in acylic and bicyclic systems (Non- classic
carbocations).
Aromatic substitution reactions:
Electrophilic, nucleophilic through benzynes, orientation of aromatic substitution (Deuterium
isotopic effect) at a saturated carbon, Partial rate factors, Selectivity relationships, General ideas
about SE1, SE2, mechanisms.
8
Text Books:
1. Reaction Mechanism in Organic Chemistry, S.M. Mukherjee and S. P. Singh, Macmillan India
Limited, 2009.
2. Organic Chemistry, Francis A. Carey, Tata McGraw Hill publishing company Limited, New
Delhi 5thEdn.,2007.
3. A guide book to mechanism in Organic Chemistry, Peter Sykes, ELBS 6thEdn.,2002.
4. Some Modern Methods of Organic Synthesis, W. Carothers, Cambridge University Press,
Cambridge, 4thEdn.,2007.
Reference Books:
1. Advanced Organic Chemistry Reactions, Mechanism & Structure, Jerry March, 4thEdn., Wiley,
2006.
2. Organic Synthesis, Michael B. Smith, McGraw-Hill, 2ndEdn.,2002.
Code Thermodynamics and Electrochemistry L T P C 56 hrs
CY5104 (Core) 4 - - 4
First, Second and III Laws of Thermodynamics: Thermodynamic Reversibility, Heat
Capacities and Heats of Reactions;Entropy Changes in Chemical Reactions; Thermodynamic
Equations of State; Free Energy and Partial Molar Properties:Gibbs-Helmholtz Equations;
Fugacity and Activity; Phase Equilibria; Partial Molar Quantities; Third Law of
Thermodynamics: Absolute Entropy of Solids, Liquids and Gases; Cryoscopic Evaluation of
Absolute Entropy of Solids
Statistical Thermodynamics: Statistical Treatment of Entropy, Maxwell-Boltzmann, Bose-
Einstein and Fermi-Dirac Statistics; Partition Functions and Their Calculation; Sackur-Tetrode
Equation.
Electrolytic Conductors: DHO Theory Inter-Ionic Atmosphere; Activity and Activity
Coefficients; Nonaqueous Electrolytes; Solid Electrolytes; Conducting Melts
9
Reference Books:
1. Fundamentals of Electrochemistry, Vladimir S Bagotsky, Wiley (2ndEdn),2011.
2. Electrochemistry, Carl H Hamann, A. Hamnett and W. Vielstich, (2 ndEdn) Wiley VCH, 2007.
Code Inorganic Chemistry Laboratory L T P C 42 hrs
CY5105 - - 3 2
1. Determination of concentration of a mixture of acids by volumetric method.
2. Determination of Fe2+ in hematite by dichrometric method.
3. Determination of available chlorine from bleaching powder.
4. Determination of Ca2+ and Mg2+ by complexometric method.
5. Determination of Ca2+ from milk powder by complexometric method.
6. Chemistry of blue printing.
7. Determination of concentration of Mn from steel by colorimetric method.
8. Determination of sulphate by semi gravimetric method.
9. Determination of Ni2+ using DMG by Gravimetric method.
10. Separation of mixture of anions and cations by paper chromatographic method.
i) Co2+ and Cu2+ and ii) Cl- and I-
11. Quantitative separation and determination of Cu 2+ by gravimetric and Zn2+ by
volumetric method.
12. Determination of Al3+ by back titration method.
Code Computational Chemistry Laboratory L T P C 42 hrs
CY5106 - - 3 2
Computer Hardware and Software: Physical Components of Desktop Computer and
Assembly; Operating Systems; Open-Access and Commercial OS
MS-Office for Chemical Applications: MS-Word for Chemical Documentation; MS-
PowerPoint for Virtual Chemical Animations; MS-EXEL for Data Processing, Graphical
Representations and Curve-Fitting
Golden Software Surfer and Grapher: Contour and Surface3-d Plots of z=f(x.y) Functions;
Gridding of z=f(x.y) kind Data Sets
Molecular Structure and Labware Drawing Software: ISIS Draw; ACD-Labs; ChemDraw
Molecular Modeling and Quantum Calculations: Use of ChemSoftChemOffice; Origin,
Sybyl, etc for Molecular Modeling, Conformational Analysis, Spectral and Physicochemical
Data Predictions; Orbital Energy and Bonding Calculations
Virtual Chemistry Experiments and Online Chemical Resources: Accessing to Online
Chemical Resources
Code Organic Chemistry Laboratory-I L T P C 42 hrs
CY5107 - - 3 2
List of Experiments: Determination of physical constants (melting and boiling points)
Purification Techniques: Crystallization, Decolourization, fractional crystallization,
10
SEMESTER-II
Molecular Polarization; Infrared and Raman Activity; Internal Coordinates and Redundancy;
Orbital Selection Rules and Electronic Spectra of Simple Atoms and Molecules.
Text Books:
1. Solid State Chemistry, D.K. Chakrabarty, , New Age International (P) Limited, Publishers,
Second Edition, 2010.
2. Principles of Physical Chemistry, B.R. Puri, L.R. Sharma and M.S. Pathania, Vishal Publishing
Co., 2011.
3. Solid State Chemistry, An Introduction, Lesley Smart, Elaine Moore, 2ndEdn.,2004.
4. Symmetry and Spectroscopy of Molecules, K. Veera Reddy, New Age International, Hyderabad,
1999.
5. Symmetry and Group Theory in Chemistry, Mark Ladd, Marwood Publishers, London, 2000.
6. Molecular Symmetry and Group Theory, Robert L. Carter, John Wiley & Sons, 1998.
Code Photochemistry and Pericyclic Reactions L T P C 56 hrs
CY5153 (Core) 4 - - 4
Organic Photochemistry:
Photochemical energy, Frank Condon Principle, Jablonski diagram, Singlet and Triplet states,
Dissipation of photochemical energy, Photosensitization, Quenching, Quantum efficiency and
Quantum yield, Experimental methods of photochemistry, Photochemistry of carbonyl and non-
carbonyl compounds.
Photo Chemical Reactions:
Norrish type I and Norrish type II cleavages, Patterno-Buchi reaction. Photoreduction,
Text Books:
1. Advanced Organic Chemistry Reactions, Mechanism & Structure, Jerry March, 4th Edition, Wiley,
2006.
2. Molecular reactions and Photochemistry, Charles Dupey and O. Chapman, Prentice Hall, 2006.
3.Reaction Mechanism in Organic Chemistry, S.M. Mukherjee and S. P. Singh, Macmillan India
Limited, 2009.
4.Pericyclic reactions, S.M. Mukherjee, Macmilan India Limited, 2009.
5.Heterocyclic Chemistry, Thomas L. Gilchrist, 3rd Edition, Pearson Education, 2007.
6.Heterocyclic Chemistry-II, J.A. Joule, K. Mills and G.F. Smith, 3rd Edition, Stanley Thornes, 2007.
13
7.Heterocyclic Chemistry, Raj K. Bansal, 5th Edition, New Age International (Pvt.Ltd.), 2006.
Reference Books:
1.The modern structural theory in Organic Chemistry, L. N. Ferguson, Pretice Hall, 2008.
2. Physical Organic Chemistry by Jack Hine, Mc. Graw Hill, 2007.
3. Mechanisms and Theory in Organic Chemistry by T.H. Lowery and K.S. Rich Gardson, 2006.
Reference Books:
1. Quantum Mechanics of Molecular Rate Processes, R. D. Levine, Dower Publications, 2011
2. Concepts of Modern Catalysis and Kinetics, I. Chorkendorff, VCH, 2013
Code Analytical Chemistry Laboratory L T P C 42 hrs
CY5155 - - 3 2
1. Estimation of Phosphoric acid in cold drinks by molybdenum blue method.
2. Simultaneous determination of two metal ions by sphectrophotometric method.
3. Determination of Fe2+ by Potentiometric method.
4. Determination of Cu2+ by conductometric titration method.
5. Determination of Cu2+ in brass by electrogravimetric method.
6. Determination of the concentration of a salt by ion exchange method.
7. Determination of concentration of alkali metals by Flame photometry.
8. Separation of Zinc and Magnesium by an ion exchange resin and estimation of Zn(II)
and Mg (II).
9. Determination of the concentration of mixture of acids by pH metric method.
14
Elective – I
15
Nucleophilic substitution and addition of arene-Metal (Rh, Ir) catalyzed C-H activation
reactions and their synthetic utility.
Text Books:
1. Organometalllics in Synthesis, Schlosser, M., A manual, John Wiley, New York, 1996.
2. Transition metals in the synthesis of complex organic molecules, Hegedus, L.S., University
Science, Book, CA, 2ndEdn.,1999.
3. Organometallic Chemistry and Catalysis,Astruc, D., Springer Verlag, 2007.
4. Organotransition metal chemistry: Applications to organic synthesis, Davies, S. G., Pergamon
Press, New York, 1986.
5. Basic Organometallic Chemistry- Concepts, Synthesis and Applications, BD Gupta and AJ
Elias, Universities Press Private Limited, India, 2011.
Reference Books:
1. Title, Author(s), Publisher, Edn, Year
2.
3.
Code Chemical Education and Research L T P C 42 hrs
CY5163 3 - - 3
Chemistry as the Central Science: Uniqueness of Chemical Stoichiometry; Chemistry of
Inanimate and Living Materials, Chemistry and Civilization; Chemistry in Product Industry;
UN Slogan, ‘Chemistry- Our Life and Our Future’; Amazements in Chemistry: Amusement in
Chemistry Classroom; Chemistry and Magic
Chemical Hazards and Disasters: Chemistry of Explosives, Poisons and Polluttants; GLPs;
Models and Tools of Chemical Education: Models and Virtual Experiments
Thrust Areas of Chemical Research: Topic by Relevance to Health, Nutrition, Energy,
Environment, Sanitation, Technology, Rural Employment, Harnessing Natural Resources;
IPR and Patents in Chemical Research and Innovations:Intellectual Property Rights in
Chemical Innovations and Products; Patent Paradigms
Text Books:
1. Chemical Education, S. Ladage and S.D. Samant, Narosa Publishing House, 2012
2. Affective Dimensions in Chemistry Education, M. Kahveci and M. Orgill, Springer (e-Book), 2015
3. Essentials of Chemical Education, H. D Barke, G. Harsch, S. Schmid and H. Gerdau, Springer,
2015
Reference Books:
1.Chemical Education: Towards Research-Based Practice - Contemporary Trends and Issues in
Science Education, J.K. Gilbert, O. de Jong, R. Justi, D. F. Treagust and J. H. van Driel, Springer,
2002
2. Multiple Representations in Chemical Education: Models and Modeling in Science Education, J.
K. Gilbert, and D. Treagust, Springer, 2009
3.All About Chemistry; Big Questions, Robert Winston, D.K. Children,2015
17
SEMESTER-III
(Organic Chemistry Specialization)
Code Organic Synthesis L T P C 56 hrs
CY6101 (Core) 4 - - 4
C-C Single Bond Formation Reactions:
Alkylation importance of enolate anions ,alkylation of relatively acidic methylene groups ,
gama alkylation of 1,3-dicarbonyl compounds; dianions in the synthesis, alkylation of ketones,
the enamine related reactions under basic conditions, Enamines, Alkylation and Acylation in
acidic medium alkylation of alpha-thio and alpha-selenocarbanions, umpolung, allylic
alkylation of alkenes, reactions of lithium organocuprates: copper-catalysed reactions of
Grignard reagents, synthetic applications of carbenes and carbenoids, formation of C-C bonds
by addition of free radicals to alkenes, some photocyclisation reactions.
Carbon-Carbon Double Bond Formation Reactions:
α-elimination, Wittig reaction, PhosphoniumYlide preparation, reaction mechanism, olefin
synthesis, stereoselective synthesis of substituted ethylenes, Fragmentation reactions,
Oxidative decarboxylation of acids, Stereospecific synthesis from 1,2-diols, Oxidation
&electroorganic oxidations and Reductions by Dissolving Metals, Reduction with hydride -
transfer reagents. Reactions at unactivated C-H bonds, the Hoffmann-Loeffler-Freytag reaction,
cyclisation reactions of nitrenes, the Barton reaction and related processes-photolysis of organic
nitrites and hypohalites, photolysis of N-nitrosoamides, reaction of monohydric alcohols with
lead tetra acetate(LTA), miscellaneous reactions.
Design of Organic Synthesis:
Synthetic strategies: Introduction and target selection and terminology, aims and objectives,
introduction, target selection, structural verification, biological activity, topological studies,
new reactions and reagents, retro synthetic analysis, terms used in retro synthetic analysis, target
molecule, functionalization, functional group interchange, disconnection synthons, synthetic
equivalent transform, retron different strategies in retro synthetic analysis, C-C disconnection,
introduction one group C-C disconnection, two group disconnections, 1,2-, 1,3-, 1,4-, 1,5-, 1,6-
difunctional compounds, applications of some important strategies in organic synthesis,
chemoselectivity, regioselectivity, stereoselectivity, cyclisation reactions(3 to 7 membered
rings), reversal polarity, amine synthesis, consecutive and convergent synthesis and some
selected synthesis.
Text Books :
1. Organic Synthesis, Michael B. Smith. 2nd Edition, McGraw Hill, 2005.
2. Some modern methods of organic synthesis, W. Carruthers, 3rd Edition, Cambridge University
Press, 2001.
3. Organic Synthesis, The disconnection Approach, S. Warren, Wiley India Edition, John
Wiley & Sons, 2007
4. Organic Chemistry, Clayden, Warren and Wothers , Oxford University Press 2001.
Text Books:
1. Text Book of Practical Organic Chemistry, Vogel A.I., 5th Edition, ELBS, 2004.
2. Experimental Organic Chemistry, Clark, F., Most Jr., John Wiley & Sons, 2002.
3. Comprehensive Practical Organic Chemistry Qualitative Analysis, V.K. Ahulwalia,
SunitaDhingra, Universities Press, 2008.
Text Books:
1. Text Book of Practical Organic Chemistry, Vogel A.I., 5th Edition, ELBS,2004.
2. Experimental Organic Chemistry, Clark, F. Most Jr., John Wiley & Sons, 2002.
3. Advanced Organic Practical Chemistry, N.K.Vishnoi, Vikas Publications Pvt. Ltd., 2006.
4. Comprehensive Practical Organic Chemistry Qualitative Analysis, V.K. Ahulwalia,
SunitaDhingra, Universities Press, 2008.
Semester-III
(Elective for Organic Chemistry Specialization)
Elective-II
Code Chemistry of Natural Products L T P C 42 hrs
CY6111 3 - - 3
Introduction: Classification of Natural Products, isolation of natural products, general methods
of structural elucidation, degradation methods. Terpenoids: Classification, Structure and
synthesis of Mono, sesqui, di, tri terpenoids, Biogenisis of terpenoids (Geraniol, Alpha-
Terpeniol, Alpha-pinene, Camphor, Cadenene, Abeitic acid, Squalene). Steroids:
Classification, structure, stereochemistry and synthesis of steroids (Cholesterol). Alkaloids:
Structure and chemistry of papaverine, Quinine, Morphine, Colchicine, Lysergic acid and
Resepine, nicotine, atropine.Vitamins: Structure and synthesis of vitamins A, B C, D, E, K.
Hormones:Thyroid hormones and steroidal hormones.
Text Books:
1. Organic Chemistry, Vol. I & II, I.L. Finar, 6 th Edition, ELBS, 2000.
2. Chemistry of Natural Products. Sujata V. Bhat, Bhimsen A. Nagasampagi, MeenakshiSivakumar. 1 st
Edition, Springer 2005.
Reference Books:
1. The Alkaloids, Bently, Oxford University Press, 2000.
2. Natural Products: Chemistry Sources, Separations, and Structures. Raymond Cooper and George
Nicola. CRC Press. 2015
Code Green Chemistry L T P C 42 hrs
CY6112 3 - - 3
Introduction to Green chemistry: Basic principles of Green Chemistry and their illustrations
with examples. Prevention of waste/by-products, Prevention/Minimization of hazardous/toxic
products, Atom Economy, Green metrics, Designing safer chemicals - different basic
approaches, Selection of appropriate auxiliary substances (solvents, separation agents etc),
Energy requirements for reactions-use of microwave, ultrasonic energy, Selection of starting
materials—use of renewable starting materials, Avoidance of unnecessary derivatization,
careful use of blocking/protection groups, Use of catalytic reagents (wherever possible) in
preference to stoichiometric reagents, Designing biodegradable products
20
Reference Books:
1.Polymers: Chemistry and Physics of Modern Materials, 3rd Edition, John W. Nicholson,
Royal Society of Chemistry, 2012.
21
2. Handbook of Sustainable Polymers: Structure and Chemistry, Ed. by Vijay Kumar Thakur,
ManjuKumari Thakur, CRC Press, 2016
1.
Code Forensic Chemistry L T P C 42 hrs
CY6114 3 - - 3
Introduction to Forensic Chemistry: Colour& Spot test, inorganic analysis, micro chemical
methods of analysis, analysis of beverages, alcoholic & non-alcoholic, medicinal preparations
containing alcohol and drugs as constituents, examination of petroleum products.
Chemistry of fire, Analysis of trace evidence – cosmetics dyes, paints pigments, quantitative
and qualitative forensic analysis of organic and inorganic industrial products, chemical
fertilizers, insecticides, metallic & non-metallic products.
Toxico-kinetics: Biotransformation, cellular sites of action, Reproductive toxicology and
teratology, Respiratory toxicology, cardiovascular toxicology, Hepatic toxicology,
Immunotoxicology.
Forensic Toxicology: Poisons, classification of poisons, sign and symptoms of common
poisons, antidotes, collection of samples.
Drugs: Drugs of abuse, classification and identification. Nacro analysis and brain
fingerprinting techniques.
Explosives: Classification, composition and characteristics of explosives, pyrotechinques,
IEDs, explosion process and affects, types of hazards, effect of blast waves on structure.
Test Books:
1. Curry, 1986. Analytical Methods in Human Toxicology.
2. Modi, J.K., 1988. Medical Jurisprudence and Toxicology. Tripathi N.M. Press Ltd.,
Allahabad.
Reference Books:
3. Curry, A.S., 1976. Poison detection in human organs.
4. Tiwari, S.N., 1987. Analytical Toxicology. Govt. of India, Publications, New Delhi.
Semester-III
(Common Electives for Both Organic and Analytical Chemistry Specializations)
Elective-III
Code Bioanalytical Chemistry L T P C 42 hrs
CY6121 3 - - 3
General principle of Analytical biochemistry- sampling in biosystems, Introduction to
Biomolecules (lipids, proteins, amino acids, Nucleic acids, enzymes, carbohydrates) specific
Examples
Principle and application of electrophoresis: principle of electro separation ,types of
electrophoreses, Instrumental electrophoresis applications of both charged and uncharged
species. Protein purification and sequencing methods. Mass spectrometric methods for
quantification of biomolecules of high molecular weights.
Centrifugation and separation: Isolation of biomolecules, basic principles of centrifugation,
types of centrifugation methods for biomolecules, Flow cytometry, principles and applications.
Immunological methods: immunoassays types, enzyme assay methods ,and Radioimmuno
methods(RIA) and biological tracers.
Sensors for identification and determinations:Biosensors for glucose, DNA and other
biologically important molecules.
Text Books:
22
Text Books:
1. Essentials of Computational Chemistry; Theories and Models, Christopher J. Cramer, Wiley; 2004
2. Computational Chemistry : Introduction to the Theory and Applications, Errol G. Lewars, Springer,
2016
3. Computational Chemistry Vol. 1 and Vol. 2, Jason Quinn, Elsevier, 2008
Reference Books:
Chemistry of Dyes: Synthesis and properties of Diphenyl, triphenyl methane dyes, Malachite
green series, Cyanin, Indigo, Anthraquinolinone, Sulfur, Xanthene, Acridinedyes. Dyes and
pigments :Basic assumptions of colors and paints, colors of organic substances, properties and
characteristics of organic and inorganic dyes and pigments, Production of organic dyes and
pigments according to the chemical composition.Industrial applications of dyes and
pigments:Acid Dyes for Nylon, Silk, & Wool (OrcoLanamide™, OrcoAcid™,Orcolan Fast™,
OrcoNylosol™, Orco Milling™, Orcolan Neutral™, Orcoset™) Application of dyes and
pigments for the textile industry, cosmetics, photography, printing, medical and others. Coating
in defense research, Nanotechnology Coatings In The Defense and aerospace industry, Self-
healing polymers and composites, Coating in medical research.
Text Books:
1. Organic Coatings: Science and Technology, Zeno W. Wicks, Jr., Frank N. Jones, S. Peter Pappas,
Douglas A. Wicks, 3rd Ed. John Wiley & Sons, 2007.
2. High-Performance Organic Coatings, Ed. by A S Khanna, Elsevier, 2008.
3. Synthetic Organic Chemistry, G. R. Chatwal and Gurudeep, Himalaya Publishers, 2009.
4. Text book of Dyes, Arora, Sonali Publications, 2009
5. Text book of synthetic Dyes, M.S. Yadav and O.D. Tyagi, Anmol Publisher, 2002
Reference Books:
1. Polymers: Chemistry and Physics of Modern Materials, 3rd Edition, John W. Nicholson, Royal
Society of Chemistry, 2012.
2. Encyclopedia of Chemical Technology, Coatings. KIRK, R. OTHMER, D. New York: Wiley, 2006
3. Protective Coatings and Thin Films: Synthesis, Characterization and Applications, Ed. by Y. Pauleau,
Péter B. Barna, Springer Science & Business Media, 1996.
24
SEMESTER-IV
(Organic Chemistry Specialization)
Code Stereoselective Synthesis L T P C 56 hrs
CY6151 (Core) 4 - - 4
Introduction, terminology and basic principles of stereoselective synthesis
Asymmetric synthesis: Topicity and prochirality, introduction, homomorphic ligands,
homomorphic faces, topicity, homotopic ligands, homotopic faces, structurally hetero topic
units, stereotopic units, enantiotopic ligands, enantiotopic faces, diastreotopic ligands,
diastereotopic faces, prochirality, symbols, partial synthesis for Enantiotopic faces Prochiral
symbols for Enantiotopic faces, Prochiral symbols for Diastereotopic faces stere selectivity and
strategies of asymmetric synthesis, substrate diastereo selectivity, product stereoselectivity,
product composition, determination of product composition, principle of stereoselectivity,
strategies of asymmetric synthesis, double stereo differentiating reactions: Diastereomeric
excess (de), and enantiomeric excess (ee). Strategies for stereo control in diastereoselective
synthesis (Preliminary account), Small ring templates, molecular walls, ring formation
reactions, pericyclic reactions coordination to metal centers, use of π-donors complexes, π-π
interactions with aromatic substituents, directed π -facial diastereoselectivity chiral auxiliaries,
achiral auxiliaries, intraanular and extraanularsetreocontrol.Nucleophilic additions to cyclic
and acyclic carbonyl compounds, Cram’s rule, Felkin’s model, addition to chelated carbonyl
compounds, Prelog’s rule and its applications, addition to chelated carbonyl compounds of H
and R to cyclic ketones ( formation of axial and equatorial alcohols), Electrophilic initiated
cyclization, Aldol reactions: (1) Achiral enolates with achiral aldehydes (2) Achiral enolates
with achiral aldehydes. (3) Chiral enolates with achiral aldehyde. (4) Chiral enolates with chiral
aldehydes.
Stereo selective Reactions
Stereo selective reactions of C=C double bond, Diastreoselective transformations involving
catalytic hydrogenation; Hydrogenation over heterogeneous catalysts; Directed hydrogenation
with soluble catalysts; synthetic applications of organoboranes and organosilanes,
hydroboration, reactions of organoboranes, corbonylation of organoboranes , reactions with
alpha halo carbonyl compounds , reactions of alkenylboranes and trialkenylboranes , freeradical
reactions of organoboranes,alkenylsilanes and allylsilanes, control of rearrangement
reactionsinvolving silicon, trimethylsilylcyanide , trimetylsilyliodide and trimethylsilyltrifliate;
Stereochemistry of free radical cyclization reactions, Prevost hydroxylation, Simon-Smith
reaction.
Enantioselective synthesis with chiral racemic catalysts, hydroboration reactions involving
chiral boranes, Chiral organometal complexes, Chiral enolate aggregates, reductions with chiral
complexes hydrides. Catalysis by chiral transition metal compexes, enantio selective
epoxidations of alkenes. Enantioselective hydrogenations.
Conformations of a few important Heterocycles
Bicyclo[2.2.1]heptanes, stability of exo and endo stereo isomers. Bicyclo[2.2.2]octane
conformations of a view important heterocycles. Aziridine, piperidine, conformations of THP.
Exo-anomeric effect, rabbit ear effect. Conformations of fused bicyclic compounds as hetero
atom. Decahydroquinoline, quinazolidine. Concept of I-strain, ring size and ease of cyclization.
Thrope-Ingoldeffect.Berrdtrule,macrolactonization, Corey-Nicholaou procedure. Baldwin
rules for cyclization reactions, required trajectories for Baldwin ring closure. Exo and endo
25
Semester-IV
(Elective for Organic Chemistry Specialization)
Elective-IV
Code Drug Development and Delivery systems L T P C 42 hrs
CY6161 3 - - 3
26
Drug Development:
Illustration of drug development through specific examples: a) Antibacterials: sulfonamides
and penicillins b)Antivirals: case studies with inhibitors of reverse transcriptase (nucleoside
reverse transcriptase- and non-nucleosidereverse transcriptase inhibitors) and protease inhibit
ors. c) Anticancer agents: antimetabolite-based approaches, those
which affect signaling pathways or structural proteins such as tubulin.Drug resistance,Drug s
ynergism and combination therapy.
Chemistry of Drugs: Introduction, Pharmalogical activity, uses and limitations of
Antipyretics, Analgesics, Sedatives, Hypnotics, Barbiturates, Sulphadrugs, Anaesthetics,
Antiseptics, Antibacterials, Diuertics, Anthelmentics, Anticoagulants, Anticonvulsants,
Antihistamines, Psychotherupeutics, Anti TB Drugs, Diagnotic agents and Antimalarials.
Semester-IV
Elective - V
(Elective for Organic Chemistry Specialization)
Code Medicinal Chemistry L T P C 42 hrs
CY6171 3 - - 3
Medicinal Chemistry:Introduction:Definition of Drug (WHO), Concept and definition of
Pharmacophore. Pharmacodynamics and Pharmacokinetics. Stereochemical aspects of drugs,
Classification of drugs based on chemical structure, pharmacological action and mechanism at
molecular level .Quantal dose, Graded dose, Efficacy, Potency, LD50, ED 50 Therapeutic
index, Margin of safety. Macro molecular targets: Receptors, Enzymes, DNA, Agonist,
Antagonist. Structure-activity relationships: Drug Discovery and Rational Drug Design a)
without lead b) lead discovery. Random screening, non-random screening. Rational approaches
of lead discovery. Factors affecting Absorption, Distribution, Metabolism, Elimination and
Toxicity. QSAR and combinatorial synthesis. Structure
activity relationships: Strategies in drug design.
Text Books:
1. Principles of Biochemistry, Lehninger, Nelson and Cox, 2nd edition, CBS, Publishers, 2001.
2. Bioorganic Chemistry, H Dugas& C. Penny, Springer- Verlag, 2002.
Reference Books:
1. Advanced Organic Chemistry Reactions, Mechanism & Structure, Jerry March, 4rd Edition, Wiley,
2007.
2. Organic Synthesis, Michael B. Smith, 2nd Edition, McGraw-Hill, 2004
3. Advanced Organic Synthesis, Jonathan Clayden, Nick Greeves, Stuart Warren, OUP Oxford, 2012
Code Advances in the Total Synthesis of Natural Products L T P C 42 hrs
28
CY6172 3 - - 3
Concepts and tactics in organic synthesis, Strategic utilization of name reactions and reagents,
Introduction to linear synthesis, Convergent, Divergent and Building block approaches,
Practical difficulties in large scale synthesis, Construction of 5-membered N and O-containing
aliphatic cyclic molecules,Heterocycles in natural product synthesis, Symmetry driven total
synthesis of Merrilactone A and Resolvin E2, Dearomatization strategies in natural product
synthesis, Protecting group free synthesis, Solid-phase chemistry in the total synthesis of non-
peptidicnatural products. Structure, absolute configuration and total synthesis of natural
products:Taxol, Epothilones A and B, Discodermolide, Brevetoxin, Camptothesin,
Diazonamide A, Sporolide B.
Text Books:
1.The Total Synthesis of Natural Products, John ApSimon, John Wiley & Sons, 2009
2.Classics in Stereoselective Synthesis, Erick M. Carreira, LisbetKvaerno, WILEY-VCH, 2008
3.The Logic of Chemical Synthesis, E. J. Corey, Xue-Min Cheng, John Wiley & Sons Inc. 1995
4.Organic Synthesis: Strategy and Control, by Paul Wyatt, Stuart Warren, Wiley, 2007
5. Total Synthesis of Natural Products: At the Frontiers of Organic Chemistry, Jie Jack Li, E.J. Corey,
Springer Science & Business Media, 2013
6.Heterocycles in Natural Product Synthesis, edited by Krishna C. Majumdar, Shital K. Chattopadhyay,
John Wiley & Sons, 2011
Reference Books:
1.Classics in total synthesis-I: Targets Strategies, Methods, K. C. Nicolaou, E. J. Sorensen, Wiley-VCH,
2000
2.Classics in total synthesis-II: More Targets Strategies, Methods, K. C. Nicolaou, Scott A. Snyder,
Wiley-VCH, 2003
3.Classics in total synthesis-III: Further Targets Strategies, Methods, K. C. Nicolaou, Jason S Chen,
Wiley-VCH, 2011.
Code Food Chemistry L T P C 42 hrs
CY6173 3 - - 3
The role ofWater, Lipids, Amino acids, Protiens, Carbohydrates, enzymes, nutrients and natural
toxicants in foods,Food additives: Artificial sweeteners – saccharin, 28yclamate, asparatame –
food flavors.Emulsifyingagents,Modernfood:Snack foods. Production of bread, bun and
biscuits. Raw materials, methods and machinery required. Candy manufacturing.
Caramelization.Fast foods, Instant foods, Dehydrated foods,Beverages:Processing and
technologies of alcoholic and non‐alcoholic beverages,basic concepts of quality assurance and
quality control applicable to the beverage industry,Soft drinks, soda, fruit juices, Introduction
to refrigeration, slow freezing, quick freezing, introduction to thawing, changes during thawing
and its effect on food, Food Irradiation- Introduction, kinds of ionizing radiations used in food
irradiation,emulsions, properties of emulsions, formation ofemulsion, emulsifying agent, food
foams. Food Adulteration:Contamination of wheat, rice, dhal, milk, butter, etc., Food poisons:
natural poisons (alkaloids, nephrotoxins), pesticides (DDT, BHC, Follidol), Chemical poisons
(KCN), Objectives of packaging, flexible packaging, properties of the followingpackaging
materials
Text Books:
1. Food Science, Srilakshmi B., New age International Pvt. Ltd. Publishers, III ed. 2003.
2. Food Processing and Preservation. Siva Sankar B., Prentice – Hall of India Pvt. Ltd., New Delhi.
2002.
3. Principles. Text book of medical biochemistry, Ramakrishnan S., Prasannam K.G and Rajan R –.
Orient Longman Ltd. III ed. 2001.
29
Reference Books:
1. Food Chemistry, By H.-D. Belitz, Werner Grosch, Peter Schieberle, 4 th Edition, Springer Science
& Business Media, 2009
Principles of Food Chemistry, John M. deMan, Springer, 2013
Elective – VI
(Common for both the Specializations)
Code Emerging Topics in Organic Synthesis L T P C 42 hrs
CY6181 3 - - 3
Recent Developments in the multicomponent reactions (MCRs): General Approaches of
MCRs, Synthesis of different heterocyclic compounds using 3, 4 and 5 component reactions,
MCRs using homogeneous and heterogeneous catalysts. Click chemistry: Importance of in
Click chemistry, Applications of click chemistry in drug discovery, biology and materials
chemistry. Alternative Solvent Systems in Organic Synthesis, Recent Developments in Ionic
liquids, Deep Eutectic Solvents, Organic reactions in aqueous medium, Tandem reactions in
Organic Synthesis, Cascade reactions in Organic Synthesis, Domino reactions in Organic
Synthesis, Metal Carbenes in Organic Synthesis, Hyper valent iodine reagents in organic
synthesis, Recent advances in Flow chemistry and Micro reactors. Soft metals in Organic
Synthesis: Silver in Organic Synthesis, Indium in Organic Synthesis, Gold in Organic
Synthesis. Nanomaterials in catalysis and Organic Synthesis, Separation techniques, process
chemistry, Trouble shooting in organic synthesis
Text Books:
1. Multicomponent Reactions: Concepts and Applications for Design and Synthesis, Raquel P. Herrera,
Eugenia Marqués-López, John Wiley & Sons., 1 Edn, 2015
2. Click Reactions in Organic Synthesis, SrinivasanChandrasekaran, John Wiley &Sons., 1 Edn, 2016.
3. Modern Gold Catalyzed Synthesis, Stephen K. Hashmi, Dean F. Toste, John Wiley & Sons, 2012
4. Modern Solvents in Organic Synthesis, Paul Knochel, Springer, 2003.
5. Catalytic Cascade Reactions, Ed. byPeng-FeiXu, Wei Wang, John Wiley & Sons, 2013.
6.Domino Reactions in Organic Synthesis, Lutz F. Tietze, Gordon Brasche, KerstenGericke, John
Wiley & Sons, 2006.
7.EnantioselectiveMulticatalysed Tandem Reactions, Hélène Pellissier, Royal Society of Chemistry,
2014.
Reference Books:
1.Microreactors in Organic Synthesis and Catalysis, Ed. by Thomas WirthTitle, John Wiley & Sons,
2008.
2. Metal Carbenes in Organic Synthesis, K H Dtz, Springer Science & Business Media, 2004.
3. Nanomaterials in Catalysis, Ed. by Philippe Serp, KarinePhilippot, John Wiley & Sons, 2012.
4.Chiral Separation Techniques: A Practical Approach, Ganapathy Subramanian,
John Wiley & Sons, 2008
Code Advanced Optical and Magnetic Resonance Methods L T P C 42 hrs
CY6182 3 - - 3
PART A: OPTICAL SPECTRAL METHODS
Atomic Spectra: Quantum Mechanics ofAtomic Absorption, Atomic Fluorescence and
AtomicEmission Spectra; Term Symbols; Stark and Zeeman Effects; ICP-MS and Isotopic
Abundance Evaluation; Stellar Radiation Analysis; Gamma-Ray Absorption Spectra
Molecular Absorption Spectra: Symmetry and Selection Rules of Transition Moment
Integrals; Allowed and Forbidden Transitions; Specular and Grazing Angle Reflection Spectra;
NIR and Vacuum UV Absorptions; Electronic Spectra of Lanthanide Complexes,
30
Organometallics and Composites; Huckels Molecular Orbitas; Frontier Molecular Orbitals; in-
situ Spectral Techniques; Surface Enhanced Raman Spectroscopy
Molecular Emission Spectra:Fluorescence Life Timeand Quantum Yields;
Photoluminescence, Non-Linear Optical Phenomena; Thermochromic, Mechanochromic and
Liochromic Properties and Applications
Text Books:
1. Modern Molecular Spectroscopy, K. S. Randhawa, McMillan, 2003
2. Electronic Absorption Spectroscopy, ,D.N. Satyanarayana, University Press, 2001
3. Magnetic Resonance Spectroscopy: ESR.NMR NQR, D.N. Satyanarayana, University Press, IK
International Publishing House, 2014
Reference Books:
1. Fluorescence Spectroscopy and Microscopy: Methods and Protocols ,Y. Engelborghsand A. J.W.G.
Visser, Humana Press, 2014
2Molecular Vibrations: The Theory of Infrared and Raman Vibrational Spectra, E.B. Wilson, Dower
Publications, Inc, 2001
3.Molecular Spectroscopy Workbench: Advances, Applications, and Practical Advice on Modern
Spectroscopic Analysis, Emil W. Ciurczak, Wiley, 1998
Code Quality Assurance and Quality Management in L T P C 42 hrs
CY6183 Chemical Industry 3 - - 3
Statistical Quality Control Techniques: Statistical treatment of data. Control charts,
Performance Evaluation- uncertainities in measurement.
Analytical Methods: Standard, official and literature methods. Validation of methods -
Ruggedness test. Good Laboratory Practices – Accreditation of QC laboratories.
Instruments and Equipment calibration and maintenance:Calibration and detection limits
–Calibration and maintenance of common laboratory instruments and equipment.
Documentation for Quality Assurance
Process approach. Quality Audits, Assessment and Certification. Case studies on ISO 9001 :
2000 in chemical industries. Total Quality Management.
Six Sigma approach to quality: Six Sigma metrics. Managing Six Sigma. ApplyingSix Sigma to chemical
industries.
Text Books:
1. Handbook of Quality Assurance for the Analytical Chemistry Laboratory, James O.Dux, Van
Nostrand Reinhold, New York, 1986
2. Training Mannual on ISO 9000 :2000 and TOM – Girdhar J. Grani.
Raj publishing House Trust, 1996.
3. Managing Six-Sigma – Forrest W. Breyfogle III. James M. Cupello
Beckimeadows, John Wiley & Sons, 2001
Text Books:
1. Polymorphism in Molecular Crystals by Joel Bernstein, Oxford University Press, 1 st Edition, 2002.
2. Polymorphism in Pharmaceutical Solids Edited by Harry Brittain
3. Solid State Characterization of Pharmaceuticals Edited by Angeline and Mark arkrzewski
4. Crystal Engineering: A textbook, Edited by G. R. Desiraju, J. J. Vittal and A. Ramanan
5. Polymorphism - In the Pharmaceutical Industry Hardcover – by R Hilfiker
Reference Books:
32
SEMESTER-III
Reference Books :
1. Surface Analysis: The Principal Techniques, John C Vikerman, Ian Gilmore (Eds.), Wiley 2 ndEdn,
2009.
2. Scanning electron microscopy and X-ray microanalysis, J Goldstein, D Newbury, D Joy, C Lyman,
P Echlin, E Lifshin, L Sawyer, J R Michael, Springer, 3 rd ed., 2003.
3. Chemical Analysis – Modern Instrumentation Methods and Techniques, Rouessac and Rouessac,
John Wiley, 6th edition, 2010.
Reference Books:
1.Practical instrumental analysis - Methods, quality assurance and laboratory management, Sergio
Petrozzi, Wiley, 1st Edn., 2012.
Manuals/Text Books:
1. A Text-book of quantitative chemical analysis of pure salts, alloys, minerals and technical products,
John Charles Oslen, Nabu, 2011.
34
Reference Books:
1.Practical instrumental analysis - Methods, quality assurance and laboratory management, Sergio
Petrozzi, Wiley, 1st Edn., 2012.
Semester-III
(Elective for Analytical Chemistry Specialization)
Elective-II
Code Environmental Chemistry L T P C 42 hrs
CY6211 3 - - 3
Chemistry of Atmosphere: Origin, composition and structure of atmosphere-particles, ions
and radicals in the atmosphere-Greenhouse effect-Causes, consequences and abatement of
Green house effect-Ozone depletion- Causes, consequences and abatement of ozone depletion-
Photochemical smog-Effects and control.
Air Pollution-Monitoring and Control: Airsampling techniques-Sources and effects, of
oxides of sulphur, oxides of nitrogen, oxides of carbon- Monitoring of air pollutants by
Instrumental methods-Monitoring and Control of particulate pollution- Monitoring of air
pollutants by Instrumental methods-Control of air pollution by raw material change, process
modification, adsorption, absorption and combustion methods.
Classification of Water Pollutants: Unique characteristics of water; Water and the Living
Environment; Water and the Non-living Environment; The Different Types of Pollutants;
Chemical Pollutants; Physical Pollutants; Physiological Pollutants; Thermal Pollution.
Monitoring of Water Pollutants: Pollution indicators, Dissolved Oxygen; Biological Oxygen
Demand; Chemical Oxygen Demand; Waste water: Constituents – Microorganisms; Solids;
Inorganic constituents, Organic matter, Water Quality requirements, pH values of Wastes and
Receiving water, Suspended solids.
Environmental Impact Assessment: Environmental Impact Assessment process in India-
Environmental acts and rules.
Control of Pollution through Green Chemistry: Basic principles of Green Chemistry-Green
catalysts-Green synthesis-Green solvents.
Text Books:
1. Fundamental Concepts of Environmental Chemistry, G.S. Sodhi, Narosa publishing House,
2ndEdn.,2005.
2. Environmental Impact Assessment Process in India and the draw backs, Aruna Murthy,
HimanshuSekharPatra, Environmental Conservation Team, 2005.
3. Waste water treatment, M.N. Rao and A.K. Datta, Oxford Publications, 2 ndEdn.,2007.
4. Environmental Science and Engineering, J. Glynn Henry and Garry W. Heinke, Prentice-Hall, Inc.,
New Jersey, USA, 2ndEdn.,
Reference Books:
2. Optical Sensors, JorgHaus, Wiley VCH, 2010.
3. Biosensors: Electrochemical and mechanical biosensors, Paul Ed Millner, Scion Publishing, 2008.
4. Optical sensors: Industrial, Environmental and Diagnostic Application (Springer Series), R
Narayanaswamy, O.S. Wolfbeis (Eds.), Springer, 2010.
5. Biosensors in Food Processing, Safety and Quality Control – Mehmet Mutlu (Ed.), CRC Press, 2010.
binding and activation by heme, non-heme and copper proteins: Iron transport and storage
proteins in bacterial and mammalian systems: Electron transport–FAD, NAD, FMN,
ubiquinone; blue copper proteins, cytochromes, iron- sulfur proteins – rubredoxin, ferridoxins,
Nitrogen-cycle enzymes: Mn in photosynthesis and O2 evolution: Photosystem I and II –
chlorophyll, Non-redox enzymes with Mg, Zn, Ni: urease, Applied bioinorganic chem–metals
in medicine, anti-cancer agents–cisplatin, radiopharmaceuticals (Tc), diagnostic (Gd in MRI)
and therapeutic agents. Toxicity of Hg, Cd, Pb and As and chelation therapy.
Text Books:
1. Principle of Bioinorganic chemistry, Lippard and Berg, Univ. Science Books, 1994.
2. Biocoordination chemistry, Fenton, Oxford chemistry primer, 1995.
3. Bioinorganic chemistry: Inorganic perspective in the chemistry of Life, Kaim and Schwederski,
1994.
4. Inorganic chemistry, Shriver, Atkins, and Langford, 1994.
5. Bioinorganic Chemistry, Bertini, Gray, Lippard and Valentine Viva books Pvt. Ltd. 1998.
Text Books:
1. Statistics and chemometrics for Analytical chemistry, James N Miller and Jane C Miller,
Pearson, 5th Edn., 2005.
2. Statistical methods in Analytical chemistry, Peter C Meier, Richard E Zund, John Wiley &
Sons, 2000.
3. Quality Assurance and Quality Control in the Analytical Chemical Laboratory,
PiotrKonieczka and JacekNamiesnik, CRC Press, 2009.
4. Quality in the Analytical Chemistry Laboratory, Elizabeth Pricard, Vicki Barwick, John
Wiley & Sons, 2008.
5. Quality Assurance in the Analytical Chemistry Laboratory, D.BrynnHibbert, Oxford
University Press, New York, 2007.
SEMESTER-IV
(Analytical Chemistry Specialization)
CY6251 (Core) 4 - - 4
High Performance Liquid Chromatography: Modern stationary phases, new detectors, chiral
mobile phases,specific applications. UPLC: Ultra performance liquid chromatography,
stationary phases for UPLC, specificapplications. Supercritical Fluid chromatography:
Principle - super critical fluids, properties of supercriticalfluids Instrumentation, detectors,
injection techniques, pressure restrictors, specific applications. IonChromatography: Principle,
- Applications in qualitative and quantitative analysis. Hyphenated techniques:
Introduction to interfaces, Principle, instrumentation and applications of GC-MS, LC-MS, LC-
MSn and GCFTIR. Multidimensional Chromatography: The importance of multidimensional
chromatography, principleand specific applications. Capillary Electrophoresis: Principle,
instrumentation, detectors, Applications.
Text Books:
1. A. Braithwaite and F.J. Smith, Chromatographic Methods, 5th Edition, Blackie Academic &
Professional(Chapman & Hall), 2009.
2. Hans-Joachim Hubschmann, Hand Book of GC-MS, Fundamentals and Applications, Wiley-VCH,
2009.
3. Robert E. Ardrey, Liquid Chromatography-Mass Spectrometry-An Introduction, Wiley, 2003.
Manuals/Text Books:
1. Quantitative chemical analysis adapted for use in laboratories, Frank Clowes and J B Coleman,
Nabu, 2010.
2.Laboratory experiments to accompany general, organic and biological chemistry - An Integrated
Approach, D B Macaulay, J M Bauer, M M Bloomfield, Wiley, 2nd Edn., 2009..
Reference Books:
1.Food analysis laboratory manual, Suzanne Nielsen, Springer, 2015.
2.Practical instrumental analysis - Methods, quality assurance and laboratory management, Sergio
Petrozzi, Wiley, 1st Edn., 2012.
38
Semester-IV
(Elective for Analytical Chemistry Specialization)
Elective-IV
Code Chemical and Electrochemical Systems of Energy L T P C 42 hrs
CY6261 3 - - 3
Thermochemistry and Chemical Kinetics of Energy Sources: Heats of Combustion of Fuels;
Differential Scanning Calorimetry; Ignition Point, Flash Point; Chemical Energy Sources; Chemistry of
Conventional and Non-Conventional Energy Materials:Petroleum Products, Petroleum Refinery;
Biomass and Goober Gas; Hydrogen as a Fuel; Coal Carbonization and Gasification;
Electrochemical Energy Systems: Primary and Secondary batteries, Solid state and molten solvent
batteries, Lithium ion batteries; Fuel cells; Current-Voltage and Current Interrupt measurements;
Porosity, Solid Oxide Fuel Cells.
Solar Energy Harnessing: Photovoltaic and Photogalvanic energy storage, Regenerative
Photoelectrochemical Cells; Photocorrosion; Electrodes with chemically modified surfaces;
Photochemical and PhotoelectrochemicalCleavageof Water: Chemically Modified Electrodes for
Water Cleavage; Coordination Chemistry of Water Cleavage
Environmental Concerns and Green Methods of Energy Sources: Quality of Chemical Energy
Sources; Monitoring of Energy Extraction from Materials; Nanochemical Methods in Energy
Extraction; Modeling of Combustion and Other Energy Tapping from Materials
Text Books:
1. Energy Systems Engineering – Evaluation and Implementation, Francis Vanek, Louis Albright,
LargusArgenent, McGraw-Hill, 2012.
2. Energy Systems and Sustainability: Power for a Sustainable Future, Bob Everett, Godfrey Boyle,
Stephen Peake and Janet Ramage, Oxford Uni Press, 2012.
3. Chemical and Electrochemical Energy Systems, R. Narayan and B. Viswanathan, Universities Press,
1998
4. Lithium Ion Batteries – Advances And Applications, Gianfranco Pistoria, Elsevier, 2014
Reference Books:
1. Dynamic Modeling of Electrochemical Energy Systems, Lucia Gauchia and Javier Sanz; LAP
Lambert Academic Publishing, 2010
2. Electrochemical Energy: Advanced Materials and Technologies (Electrochemical Energy Storage
and Conversion, Pei Kang Shen Chao-Yang Wang, San Ping Jiang (Ed), CRC, 2016
3. Tomorrow’s Energy: Hydrogen, Fuel Cells, and the Prospects for A Cleaner Planet, Peter Hoffmann,
Byron Dorgan, MIT Press, 2012
4. Solar Energy Conversion, Yuri V Pleskov, Springer-Verlag, 1990
5. Solar Energy Conversion – Dynamics of Interfacidal Electron and Excitation Transfer, Piotrowiak,
Laurie Peter, Heinz Frei and Tim Zhao, RSC, 2013
Text Books :
39
1. Surface analysis methods in materials science, D J O’Connor, Brett A Sexton, Roger S C Smart
(Eds), Springer Series in surface sciences, 2 ndEdn., 2010.
2. Surface Analysis: The Principal Techniques, John C Vikerman, Ian Gilmore (Eds.), 2 ndEdn., Wiley,
2009.
3. An introduction to surface analysis by XPS and AES, John F Watts, John Wolstenholme, Wiley,
2ndEdn., 2003.
4. Surface enhanced Raman spectroscopy, Sebastian schlucker, Wolfgang Kiefer (Eds), Wiley VCH,
2011.
Reference Books:
1. Principles of Instrumental Analysis, Skoog, Holler, Crouch, Cengage Learning, 6 thEdn.,2010.
2. Instrumental Methods of Analysis, Willard, Merritt, Dean, Settle, CBS / Wadsworth Publ. Co.,
7thEdn.,1988.
3. Practical Surface Analysis by Auger and X-ray Photoelectron Spectroscopy, D. Briggs, M.P. Seah,
John Wiley, 1983.
4. Surface and thin film analysis, GernotFriedbacher, Henning Bubert (Eds), Wiley-VCH,
2ndEdn.,2011.
5. Surface enhanced Raman scattering: Physics and applications, KatrinKneipp, Martin Moskovits,
HaraldKneipp (Eds), Springer, 2010.
Reference Books:
1. Title, Author(s), Publisher, Edn, Year
2.
3.
Elective - V
Code Advanced Electroanalytical Methods L T P C 42 hrs
CY6271 3 - - 3
40
Steady state and potential step techniques: linear sweep voltammetry, differential pulse
voltammetry, Stripping voltammetry: anodic stripping and cathodic stripping voltammetry,
adsorptive stripping voltammetry, principles and applications. Cyclic Voltammetry: principles
and applications. Hydrodynamic measurements, Rotating disk and ring disk electrodes, flow-
cell analysis. Chronomethods, principles, chrono-potentiometric, -amperometric and -
coulometric measurements, instrumentation and applications. Electrocatalysis of hydrogen and
oxygen evolution reactions. Electrochemical sensors: Potentiometric and amperometric
sensors, principles, instrumentation, and applications.
Electrochemical impedance spectroscopic measurements, principles and applications,
Potentiodynamic polarization studies, Tafel methods. Electrochemical quartz crystal
microbalance, principle, thin layer coatings, electropolymerization and electrodeposition of
metals, applications.
Electrochemical supercapacitors: comparison with batteries for energy storage, density and
charge-discharge behaviour, energy and power densities of storage devices, Pseudocapacitance,
ruthenium and porous materials, applications.
Electrochemical scanning tunneling microscopy and Electrochemical atomic force microscopy,
principles, instrumentation, Potential-UV-VIS measurements, Potential-Infrared
measurements, applications.
Text Books:
1. Electrochemical methods: Fundamentals and applications, Allen J Bard and Larry R Faulkner, John
Wiley, 2nd Edn., 2010.
2.Electroanalytical methods: Guide to experiments and applications, Fritz Scholz, Springer, 2nd Edn.,
2010.
3.Fundamentals of Electroanalytical Chemistry, P M S Monk, John Wiley, 2003.
4.Electrochemical supercapacitors - Scientific fundamentals and technological applications, B E
Conway, Springer, 2014.
Reference Books:
1.Analytical Electrochemistry, Joseph Wang, John Wiley, 3rd Edn., 2006.
2.Electrochemistry of Functional Supramolecular Systems, Paola Ceroni, Alberto Credi and
MargheritaVenturi (Ed.), John Wiley, 2010.
Text Books:
1. Introduction to GC-MS Coupling, Stéphane Bouchonnet, CRC Press, 2013
2.LC-MS in Drug Bioanalysis, Q. Alan Xu and Timothy L. Madden, Springer, 2012
Reference Books:
1.Identification and Quantification of Drugs, Metabolites and Metabolizing Enzymes by LC-MS,
SwapanChowdhury, Elsevier, 2005
41
CY6273 3 - - 3
Other Industrialy important catalysts and process : Wilkinson catalyst, Zeigler Natta
catalyst, Fisher trope synthesis, Heck reaction, Suzuki coupling reaction, Haber process, Bio-
diesel production, Dye degradation and Photocatalysis.
Text Books:
Molecular sieves of synthesis and Identification, R. Szostak, Van Nostrand Reinhold catalysis
series, New York, 1989.