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Model Test Paper 2013 B.Sc.-I Biotech.: Immunology

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Model Test Paper 2013 B.Sc.-I Biotech.

Immunology
Question No. 1 is compulsory. Answer five questions in all, selecting one question from each pair. 1. Fill in the blanks:a) _____________ immunity is associated with specificity and memory. b) T helper cells express the membrane glycoprotein molecules ________ and are restricted to recognizing antigen bound to __________ on antigen presenting cell. c) The primary role of natural killer cells is the destruction of __________ and _________. d) _____________ and _____________ are the cells of the immune system that phagocytose and degrade antigens. e) __________ has a bilobed nucleus and granulated cytoplasm that stains with the __________. f) ___________ is the transplant of tissue from one person to another person, for example ____________. g) IgA is dimeric antibody and is primarily in secretions such as ________, ___________ and ____________. h) ___________ and __________ cells play an important role in the development of allergic reactions. i) The synthesis of T cells takes place in ____________ and maturation in ___________. j) Type I hypersensitivity can be exemplified by __________, _________ and ___________. 10X1 2. Define non-specific or innate immunity. Describe different types of barriers or lines of defences comprising innate immunity. Or Write short notes on any two: a) Natural Killer cells b) Lymph node c) Granulocytes 5+5 2+8

3. Discuss the distinguishing features of five different classes of immunoglobulins. 10 Or Describe briefly any two of the following:a) Radioimmunoassay b) Hybridoma technology c) Cytosolic pathway of antigen processing and presentation 5+5

4. What is complement system? Explain in detail the alternative pathway of complement system. Or Write short notes on any two:a) Type I hypersensitivity b) General properties of cytokines c) Antibody dependent cell mediated cytotoxicity 5. Describe the defence mechanism of host against bacterial infections. Or Write short notes on any two:a) Types of tumour antigens b) Autoimmune disorders c) Vaccines 5+5

2+8

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