Barsanalina - Assignment For Chapter 16 Adaptive Immunity

Name: Ralph B.
barsanalina Score: _______

Class Schedule: We(7:30-9:00am)The(10:30-12:00pm,) Date: April 1, 2022
Assignment for Chapter 16 Adaptive Immunity

QUESTIONS FOR REVIEW
Multiple Choice
B 1. Antibodies function to __________________.
a. directly destroy foreign organ graft b. mark invading organisms for destruction
c. kill intracellular viruses d. directly promote cytokine synthesis e.
stimulate T cell growth
E 2. MHC class II molecules bind to __________________ and trigger __________________.
a. endogenous antigens; cytotoxic T cell b. exogenous antigens; cytotoxic T cells
c. antibodies; B cells d. endogenous antigens; helper T cells e.
exogenous antigens; helper T cells
E 3. Rejection of a foreign skin graft is an example of _____________________________________.
a. destruction of virus-infected cells b. tolerance c. antibody-mediated immunity
d. a secondary immune response e. a cell-mediated immune response B 4. An
autoantigen is _____________________________________.
a. an antigen from normal microbiota b. a normal body component c. an artificial antigen
d. any carbohydrate antigen e. nucleic acid
D 5. Among the key molecules that control cell-mediated cytotoxicity are ___________________.
a. perforin b. immunoglobulins c. complement d. cytokines e. interferons
A 6. Which of the following lymphocytes predominates in blood? a. T cells b. B cells
c. plasma cells d. memory cells e. All are about equally prevalent
C 7. The major class of immunoglobulin found on the surfaces of the walls of the intestines and airways is secretory
_________________.
a. IgG b. IgM c. IgA d. IgE e. IgD
D 8. Which cells express MHC class I molecules in a patient? a. red blood cells b. antigen-presenting cells only
c. neutrophils only d. all nucleated cells e. dendritic cells only E
9. In which of the following sites in the body can B cells be found?
a. lymph nodes b. spleen c. red bone marrow d. intestinal wall e. all of these
A 10. Tc cells recognize epitopes only when the latter are held by _____________________________________.
a. MHC proteins b. B cells c. interleukin 2 d. granzyme
Modified True/False
Mark each statement as either true or false. Rewrite false statements to make them true by changing the
underlined words.
1. Antigen-Presenting Cells MHC class II molecules are found on T cells.
2. TRUE Apoptosis is the term used to describe cellular suicide.
3. Cytotoxic Lymphocytes with CD8 glycoprotein are helper T cells.
4. Plasma Cells Cytotoxic T cells secrete immunoglobulin.
5. Humoral Secretion of antibodies by activated B cells is a form of cell-mediated immunity.
Matching
Match each cell in the left column with its associated protein from the right column.
1. D Plasma cell A. MHC II molecule
2. C Cytotoxic T cell B. Interleukin 4
3. B Th2 cell C. Perforin and granzyme
4. A Dendritic cell D. Immunoglobulin
Match each type of immunity in the left column with its associated example from the right column.
1. D Artificially acquired passive immunotherapy A. Production of IgE in response to pollen

2. A Naturally acquired active immunity B. Acquisition of maternal antibodies in breast milk
3. B Naturally acquired passive immunity C. Administration of tetanus toxoid
4. C Artificially acquired active immunity D. Administration of antitoxin
VISUALIZE IT!
a) Label the parts of the immunoglobulin below.
a) Antigen-Binding Sites
b) Heavy Chain
c) Light Chain
d) Constant Region of Light Chain
e) Heavy Chain
f) (Stem) Fc Region
g) Fab Fragment
h) Constant Region of Heavy Chain
b) The nearby image is a transmission electron micrograph of a dendritic cell. Indicate where a scientist
could find molecules of MHC I and MHC II. Label a pseudopod and a vesicle.
MHC I & MHC II
Can be found in
Cytoplasmic
membrane
Vesicles
Pseudopod
Short Answer
1. When is antigen processing an essential prerequisite for an immune response?
Antigen presentation serves to ensure adaptive immune responses are initiated to invading
microorganisms. Therefore, in an effort to survive in the host, pathogens target antigen presentation
pathways and disable their function. Antigen processing is essential because it helps determine whether
the antigen is endogenous or exogenous.
2. Why does the body have both antibody and cell-mediated immune responses?
The reason why our body has both antibody and cell-mediated immune responses is because
these are essential for antiviral defenses. Each have specific contributions that varies with each type of
immune response which depends on the virus and the host.
Using the following terms, fill in the following concept map that describes antibodies.
Secreted Immunoglobulins
Plasma Cells IgA IgM

Antigens
IgD IgG
Antigen stimulated IgE
B cells
Inflammation Neutralization Death by oxidation Agglutination
Phagocytosis Target bacteria

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Name: Ralph B.

barsanalina Score: _______

Assignment for Chapter 16 Adaptive Immunity

1. D Artificially acquired passive immunotherapy A. Production of IgE in response to pollen

Plasma Cells IgA IgM

Inflammation Neutralization Death by oxidation Agglutination

Phagocytosis Target bacteria

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