The twister ribozyme motif has been identified by bioinformatic means very recently.
Currently, four crystal structures with ordered active sites together with a series of chemical …

Twister RNAs represent a recently discovered class of natural ribozymes that promote rapid
cleaving of RNA backbones. Although an abundance of theoretical, biochemical, and …

We present a crystal structure at 2.3-Å resolution of the recently described nucleolytic
ribozyme twister. The RNA adopts a previously uncharacterized compact fold based on a …

The catalytic properties of RNA have been a subject of fascination and intense research
since their discovery over 30 years ago. Very recently, several classes of nucleolytic …

The twister RNA is a recently discovered nucleolytic ribozyme that is present in both bacteria
and eukarya. While its biological role remains unclear, crystal structure analyses and …

Twister is a recently discovered RNA motif that is estimated to have one of the fastest known
catalytic rates of any naturally occurring small self-cleaving ribozyme. We determined the 4.1 …

We describe the multifactorial origins of catalysis by the twister ribozyme. We provide
evidence that the adenine immediately 3′ to the scissile phosphate (A1) acts as a general …

The field of small self-cleaving nucleolytic ribozymes has been invigorated by the recent
discovery of the twister, twister-sister, pistol and hatchet ribozymes. We report the crystal …

The recently discovered twister ribozyme is thought to utilize general acid–base catalysis in
its self-cleavage mechanism, but the roles of nucleobases and metal ions in the mechanism …

Small self-cleaving nucleolytic ribozymes contain catalytic domains that accelerate site-
specific cleavage/ligation of phosphodiester backbones. We report on the 2.9-Å crystal …