Cellular small molecules contribute to twister ribozyme catalysis
KJ Messina, PC Bevilacqua - Journal of the American Chemical …, 2018 - ACS Publications
The number of self-cleaving small ribozymes has increased sharply in recent years.
Advances have been made in describing these ribozymes in terms of four catalytic …
Advances have been made in describing these ribozymes in terms of four catalytic …
The 3′-untranslated region of mRNAs as a site for ribozyme cleavage-dependent processing and control in bacteria
M Felletti, A Bieber, JS Hartig - RNA biology, 2017 - Taylor & Francis
Besides its primary informational role, the sequence of the mRNA (mRNA) including its 5′-
and 3′-untranslated regions (UTRs), contains important features that are relevant for post …
and 3′-untranslated regions (UTRs), contains important features that are relevant for post …
SHAPE probing pictures Mg2+-dependent folding of small self-cleaving ribozymes
C Gasser, J Gebetsberger… - Nucleic Acids …, 2018 - academic.oup.com
Self-cleaving ribozymes are biologically relevant RNA molecules which catalyze site-
specific cleavage of the phosphodiester backbone. Gathering knowledge of their three …
specific cleavage of the phosphodiester backbone. Gathering knowledge of their three …
Biochemical analysis of hatchet self-cleaving ribozymes
S Li, CE Lünse, KA Harris, RR Breaker - Rna, 2015 - rnajournal.cshlp.org
Hatchet RNAs are members of a novel self-cleaving ribozyme class that was recently
discovered by using a bioinformatics search strategy. The consensus sequence and …
discovered by using a bioinformatics search strategy. The consensus sequence and …
High‐throughput mutational analysis of a twister ribozyme
S Kobori, Y Yokobayashi - Angewandte Chemie International …, 2016 - Wiley Online Library
Recent discoveries of new classes of self‐cleaving ribozymes in diverse organisms have
triggered renewed interest in the chemistry and biology of ribozymes. Functional analysis …
triggered renewed interest in the chemistry and biology of ribozymes. Functional analysis …
Structural basis for the guanosine requirement of the hairpin ribozyme
To form a catalytically active complex, the essential nucleotides of the hairpin ribozyme,
embedded within the internal loops of the two domains, must interact with one another. Little …
embedded within the internal loops of the two domains, must interact with one another. Little …
Modulating RNA structure and catalysis: lessons from small cleaving ribozymes
C Reymond, JD Beaudoin, JP Perreault - Cellular and Molecular Life …, 2009 - Springer
RNA is a key molecule in life, and comprehending its structure/function relationships is a
crucial step towards a more complete understanding of molecular biology. Even though …
crucial step towards a more complete understanding of molecular biology. Even though …
Small self-cleaving ribozymes
AR Ferré-D'Amaré, WG Scott - Cold Spring Harbor …, 2010 - cshperspectives.cshlp.org
The hammerhead, hairpin, hepatitis delta virus (HDV), Varkud Satellite (VS), and glmS
ribozymes catalyze sequence-specific intramolecular cleavage of RNA. They range between …
ribozymes catalyze sequence-specific intramolecular cleavage of RNA. They range between …
Conformational Heterogeneity at Position U37 of an All-RNA Hairpin Ribozyme with Implications for Metal Binding and the Catalytic Structure of the S-Turn,
S Alam, V Grum-Tokars, J Krucinska, ML Kundracik… - Biochemistry, 2005 - ACS Publications
The hairpin ribozyme is an RNA enzyme that performs site-specific phosphodiester bond
cleavage between nucleotides A− 1 and G+ 1 within its cognate substrate. Previous …
cleavage between nucleotides A− 1 and G+ 1 within its cognate substrate. Previous …
Catalytic strategies of self-cleaving ribozymes
JC Cochrane, SA Strobel - Accounts of chemical research, 2008 - ACS Publications
Five naturally occurring nucleolytic ribozymes have been identified: the hammerhead,
hairpin, glmS, hepatitis delta virus (HDV), and Varkud satellite (VS) ribozymes. All of these …
hairpin, glmS, hepatitis delta virus (HDV), and Varkud satellite (VS) ribozymes. All of these …