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TR200103430T2 - Aminoalkil ile ikame edilmiş (benzodioksan, benzofuran veya benzopiran) türevleri - Google Patents

Aminoalkil ile ikame edilmiş (benzodioksan, benzofuran veya benzopiran) türevleri

Info

Publication number
TR200103430T2
TR200103430T2 TR2001/03430T TR200103430T TR200103430T2 TR 200103430 T2 TR200103430 T2 TR 200103430T2 TR 2001/03430 T TR2001/03430 T TR 2001/03430T TR 200103430 T TR200103430 T TR 200103430T TR 200103430 T2 TR200103430 T2 TR 200103430T2
Authority
TR
Turkey
Prior art keywords
benzodioxane
benzopyran
benzofuran
derivatives
aminoalkyl substituted
Prior art date
Application number
TR2001/03430T
Other languages
English (en)
Inventor
Van Emelen Kristof
Frans Leopold De Bruyn Marcel
Original Assignee
Janssen Pharmaceutica N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica N.V. filed Critical Janssen Pharmaceutica N.V.
Publication of TR200103430T2 publication Critical patent/TR200103430T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pyrane Compounds (AREA)

Abstract

Mevcut bulus, karnin vücudun merkezine dogru uzanan kismini rahatlama özelligine sahip yeni aminoalkilkroman bilesiklerine iliskindir. Bulus ayni zamanda bu tür bilesiklerin söz konusu bilesikleri içeren farmasötik bilesimlerin hazirlanmasina ve söz konusu bilesiklerin bir ilaç olarak kullanimina iliskin yöntemleri de göstermektedir.
TR2001/03430T 1999-06-02 2000-05-23 Aminoalkil ile ikame edilmiş (benzodioksan, benzofuran veya benzopiran) türevleri TR200103430T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP99201747 1999-06-02

Publications (1)

Publication Number Publication Date
TR200103430T2 true TR200103430T2 (tr) 2002-06-21

Family

ID=8240260

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2001/03430T TR200103430T2 (tr) 1999-06-02 2000-05-23 Aminoalkil ile ikame edilmiş (benzodioksan, benzofuran veya benzopiran) türevleri

Country Status (33)

Country Link
US (2) US6864273B1 (tr)
EP (1) EP1187829B1 (tr)
JP (1) JP2003501427A (tr)
KR (1) KR100699512B1 (tr)
CN (1) CN1150191C (tr)
AR (1) AR033334A1 (tr)
AT (1) ATE256125T1 (tr)
AU (1) AU773773B2 (tr)
BG (1) BG65269B1 (tr)
BR (1) BR0011237A (tr)
CA (1) CA2374902C (tr)
CZ (1) CZ20014177A3 (tr)
DE (1) DE60007124T2 (tr)
DK (1) DK1187829T3 (tr)
EA (1) EA004645B1 (tr)
EE (1) EE04780B1 (tr)
ES (1) ES2212774T3 (tr)
HR (1) HRP20010868A2 (tr)
HU (1) HUP0201404A3 (tr)
IL (2) IL146840A0 (tr)
MX (1) MXPA01012330A (tr)
MY (1) MY120618A (tr)
NO (1) NO319953B1 (tr)
NZ (1) NZ514993A (tr)
PL (1) PL198552B1 (tr)
PT (1) PT1187829E (tr)
SI (1) SI1187829T1 (tr)
SK (1) SK285619B6 (tr)
TR (1) TR200103430T2 (tr)
TW (1) TWI289559B (tr)
UA (1) UA73122C2 (tr)
WO (1) WO2000075136A1 (tr)
ZA (1) ZA200109860B (tr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA01012323A (es) 1999-06-02 2002-07-22 Janssen Pharmaceutica Nv Derivados de (benzodioxano, benzofurano, o benzopirano) pirrolidinilo, piperidinilo u homopiperidinilo sustituidos.
JO2352B1 (en) 2000-06-22 2006-12-12 جانسين فارماسيوتيكا ان. في Compounds for the treatment of non-adaptation of the bottom of the uterus
JO2654B1 (en) 2000-09-04 2012-06-17 شركة جانسين فارماسوتيكا ان. في Multiple aryl caroxa amides are useful as lipid - lowering agents
JO2409B1 (en) 2000-11-21 2007-06-17 شركة جانسين فارماسوتيكا ان. في Second-phenyl carboxy amides are useful as lipid-lowering agents
CA2481916C (en) * 2002-04-08 2013-02-26 Zeria Pharmaceutical Co., Ltd. A therapeutic agent for impaired gastric accommodation
MX2007009783A (es) 2005-02-17 2007-08-22 Wyeth Corp Derivados de indol, benzotiofeno, benzofurano e indeno cicloalquilfusionados.
CA2853024C (en) 2011-11-11 2017-08-22 Pfizer Inc. 2-thiopyrimidinones
JP2018515480A (ja) 2015-05-05 2018-06-14 ファイザー・インク ２−チオピリミジノン

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3910930A (en) 1973-01-04 1975-10-07 Janssen Pharmaceutica Nv 1-{55 1-{8 2-(1,4-Benzodioxan-2-yl)-2-hydroxyethyl{9 -4-piperidyl{56 -2-benzimidazolinones
US3929801A (en) 1973-11-20 1975-12-30 Janssen Pharmaceutica Nv 2-Benzimidazolinones
GR71865B (tr) 1978-03-20 1983-07-07 Ciba Geigy
DE2852945A1 (de) 1978-12-07 1980-06-26 Boehringer Sohn Ingelheim Benzodioxanyl-hydroxyaethylpiperidyl- imidazolidinone, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
US4329348A (en) 1979-02-26 1982-05-11 Ciba-Geigy Corporation N-Oxacyclic-alkylpiperidines as psychostimulants
DE3124366A1 (de) 1981-06-20 1982-12-30 Hoechst Ag, 6000 Frankfurt N-oxacyclyl-alkylpiperidin-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische praeparate und deren verwendung
FR2533584B1 (fr) 1982-09-28 1986-03-21 Pasteur Institut Procede de detection du pouvoir mutagene de substances, susceptibles d'induire la deterioration d'adn cellulaires, mettant en jeu la production d'une reponse sos
DE3901814A1 (de) 1988-07-28 1990-02-01 Bayer Ag Substituierte aminomethylzetraline sowie ihre heterocyclischen analoga
DE4140540A1 (de) 1991-12-09 1993-06-17 Bayer Ag Neue azaheterocyclylmethyl-chromane
SI9300097B (en) * 1992-02-27 2001-12-31 Janssen Pharmaceutica Nv (benzodioxan, benzofuran or benzopyran) alkylamino) alkyl substituted guanidines
DE4319038A1 (de) * 1993-06-08 1994-12-15 Bayer Ag Verwendung von teilweise bekannten substituierten Chromanen als Arzneimittel, neue Wirkstoffe und Verfahren zu ihrer Herstellung
EP0714396B1 (en) 1993-08-19 2003-12-10 Janssen Pharmaceutica N.V. Vasocontrictive dihydrobenzopyran derivatives
US5541199A (en) 1995-06-02 1996-07-30 American Home Products Corporation Chroman-2-ylmethylamino derivatives
FR2744451B1 (fr) 1996-02-01 1998-04-24 Pf Medicament Nouvelles imidazolidinones, pyrimidinones, et 1,3-diazepin-2 -ones, leur preparation et leurs applications en therapeutique
US6133277A (en) * 1997-12-05 2000-10-17 Janssen Pharmaceutica N.V. (Benzodioxan, benzofuran or benzopyran) derivatives having fundic relaxation properties
MXPA01012323A (es) 1999-06-02 2002-07-22 Janssen Pharmaceutica Nv Derivados de (benzodioxano, benzofurano, o benzopirano) pirrolidinilo, piperidinilo u homopiperidinilo sustituidos.
JO2352B1 (en) 2000-06-22 2006-12-12 جانسين فارماسيوتيكا ان. في Compounds for the treatment of non-adaptation of the bottom of the uterus

Also Published As

Publication number Publication date
AR033334A1 (es) 2003-12-17
US20050096378A1 (en) 2005-05-05
BG106156A (en) 2002-05-31
CA2374902C (en) 2009-09-15
NZ514993A (en) 2003-05-30
US6864273B1 (en) 2005-03-08
ZA200109860B (en) 2003-05-28
EA200101236A1 (ru) 2002-08-29
CN1353707A (zh) 2002-06-12
DK1187829T3 (da) 2004-04-13
HRP20010868A2 (en) 2003-04-30
SK285619B6 (sk) 2007-05-03
MXPA01012330A (es) 2002-07-30
IL146840A0 (en) 2002-07-25
TWI289559B (en) 2007-11-11
PL198552B1 (pl) 2008-06-30
PL352112A1 (en) 2003-07-28
IL146840A (en) 2006-12-10
DE60007124T2 (de) 2004-09-23
SI1187829T1 (en) 2004-04-30
PT1187829E (pt) 2004-04-30
BG65269B1 (bg) 2007-11-30
CZ20014177A3 (cs) 2002-05-15
EP1187829A1 (en) 2002-03-20
MY120618A (en) 2005-11-30
BR0011237A (pt) 2002-03-05
DE60007124D1 (de) 2004-01-22
EA004645B1 (ru) 2004-06-24
CA2374902A1 (en) 2000-12-14
HUP0201404A2 (en) 2002-08-28
AU5525600A (en) 2000-12-28
CN1150191C (zh) 2004-05-19
NO20015903L (no) 2001-12-03
ATE256125T1 (de) 2003-12-15
KR20010110806A (ko) 2001-12-13
NO319953B1 (no) 2005-10-03
KR100699512B1 (ko) 2007-03-26
EP1187829B1 (en) 2003-12-10
ES2212774T3 (es) 2004-08-01
SK17032001A3 (sk) 2002-07-02
UA73122C2 (en) 2005-06-15
EE200100639A (et) 2003-02-17
JP2003501427A (ja) 2003-01-14
HUP0201404A3 (en) 2005-02-28
NO20015903D0 (no) 2001-12-03
US7273862B2 (en) 2007-09-25
EE04780B1 (et) 2007-02-15
AU773773B2 (en) 2004-06-03
WO2000075136A1 (en) 2000-12-14

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