MXPA05004247A - Cromonas y derivados de cromona y usos de los mismos. - Google Patents
Cromonas y derivados de cromona y usos de los mismos.Info
- Publication number
- MXPA05004247A MXPA05004247A MXPA05004247A MXPA05004247A MXPA05004247A MX PA05004247 A MXPA05004247 A MX PA05004247A MX PA05004247 A MXPA05004247 A MX PA05004247A MX PA05004247 A MXPA05004247 A MX PA05004247A MX PA05004247 A MXPA05004247 A MX PA05004247A
- Authority
- MX
- Mexico
- Prior art keywords
- chromones
- chromone derivatives
- present
- derivatives
- disorders
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
- C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
- C07D311/30—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
Abstract
La presente invencion se refiere a las cromonas, los nuevos derivados de cromona, y las formulaciones farmaceuticas que contienen los mismos, y los metodos de uso de los mismos. Los usos de la presente invencion incluyen, pero no estan limitados a, el uso para la prevencion o tratamiento de choque septico, dano a organos y otros trastornos. Los compuestos descritos en la presente pueden ser formas de sales y tambien compuestos solubles en agua.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US42030602P | 2002-10-22 | 2002-10-22 | |
US45377103P | 2003-03-11 | 2003-03-11 | |
PCT/US2003/033578 WO2004037193A2 (en) | 2002-10-22 | 2003-10-22 | Chromones and chromone derivatives and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA05004247A true MXPA05004247A (es) | 2005-10-18 |
Family
ID=32179793
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA05004247A MXPA05004247A (es) | 2002-10-22 | 2003-10-22 | Cromonas y derivados de cromona y usos de los mismos. |
Country Status (6)
Country | Link |
---|---|
US (1) | US8138165B2 (es) |
EP (1) | EP1556031A4 (es) |
AU (1) | AU2003282999A1 (es) |
CA (1) | CA2502975A1 (es) |
MX (1) | MXPA05004247A (es) |
WO (1) | WO2004037193A2 (es) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6884783B2 (en) | 2002-05-03 | 2005-04-26 | Unigen Pharmaceuticals, Inc. | 7-Hydroxy chromones as potent antioxidants |
US20060134015A1 (en) | 2004-12-22 | 2006-06-22 | Trivedi Harsh M | Methods for use of oral care compositions containing free-B-ring flavonoid anti-oxidants |
CN101171241A (zh) * | 2005-03-11 | 2008-04-30 | 密执安州立大学董事会 | 抗细胞凋亡的bcl-2家族成员的色烯-4-酮抑制剂及其应用 |
GB0509956D0 (en) * | 2005-05-16 | 2005-06-22 | Danisco | Method |
TWI454261B (zh) * | 2007-01-09 | 2014-10-01 | Unigen Inc | 作為治療劑之色酮類 |
EP2478901A3 (en) * | 2007-02-14 | 2012-11-14 | Mars Incorporated | Neurogenic compounds |
CN101062029B (zh) * | 2007-05-21 | 2010-05-19 | 中国药科大学 | 汉黄芩素在制备治疗胃癌的药物中的应用 |
KR100898330B1 (ko) | 2007-09-12 | 2009-05-20 | 건국대학교 산학협력단 | 항암성을 갖는 새로운 플라보노이드 유도체 7-o-(3-벤질옥시프로필)-5,4' -o-디메틸-아피제닌, 그 제법 및 그것을 포함하는 항암 조성물 |
WO2009129372A1 (en) * | 2008-04-18 | 2009-10-22 | Shenogen Pharma Group Ltd. | Compounds and methods for treating estrogen receptor-related diseases |
US9895344B2 (en) | 2008-07-25 | 2018-02-20 | Emory University | Treating various disorders with 7,8-dihydroxyflavone and derivatives thereof |
US20100189653A1 (en) * | 2008-10-10 | 2010-07-29 | Wendye Robbins | Pyrone analogs for therapeutic treatment |
CN101486715B (zh) * | 2009-02-09 | 2013-01-23 | 沈阳药科大学 | 噁嗪类化合物及其抗血小板聚集的用途 |
CN102993147B (zh) * | 2009-02-09 | 2015-09-09 | 沈阳药科大学 | 4-色酮及4-色满酮类化合物和用途 |
US20100222421A1 (en) * | 2009-02-27 | 2010-09-02 | National Defense Medical Center | Usage of Baicalein in the Preparation of a Pharmaceutical Composition for the Treatment of Traumatic Brain Injury |
JP2012525331A (ja) * | 2009-04-27 | 2012-10-22 | リメリック バイオファーマ, インコーポレイテッド | 治療的処置のためのリン酸化ピロン類似体 |
CN103965172A (zh) * | 2009-09-11 | 2014-08-06 | 盛诺基医药科技有限公司 | 治疗雌激素受体相关疾病的化合物及其方法 |
US8759548B2 (en) | 2010-02-12 | 2014-06-24 | N30 Pharmaceuticals, Inc. | S-nitrosoglutathione reductase inhibitors |
JP5639665B2 (ja) | 2010-02-12 | 2014-12-10 | エヌサーティー・ファーマシューティカルズ・インコーポレーテッド | S−ニトロソグルタチオンレダクターゼのクロモン阻害剤 |
EP2579870B1 (en) | 2010-06-09 | 2018-02-14 | Emory University | Trkb agonists and methods of use |
CA2807199C (en) * | 2010-07-27 | 2020-07-07 | Trustees Of Boston University | Flavonoid-derived aryl hydrocarbon receptor modulators useful in the treatment of cancer |
WO2012066330A1 (en) | 2010-11-17 | 2012-05-24 | Heptares Therapeutics Limited | Compounds useful as a2a receptor inhibitors |
CN102516301B (zh) * | 2011-11-28 | 2016-08-03 | 江苏天地人和药业有限公司 | 用于治疗的汉黄芩素衍生物 |
US9593125B2 (en) | 2012-07-27 | 2017-03-14 | Emory University | Heterocyclic flavone derivatives, compositions, and methods related thereto |
WO2015116460A1 (en) * | 2014-01-28 | 2015-08-06 | Virginia Commonwealth University | 2-substituted-5-hydroxy-4h-chromen-4-ones as novel ligands for the serotonin receptor 2b (5-ht2b) |
WO2017146309A1 (ko) | 2016-02-22 | 2017-08-31 | (주)오스티오뉴로젠 | 유파틸린의 상피간엽이행 억제 활성을 이용한 섬유증 예방 및 치료용 약제학적 조성물로서의 새로운 용도 |
WO2017156520A1 (en) * | 2016-03-11 | 2017-09-14 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Icariin and icaritin derivatives |
CN110115712A (zh) * | 2019-07-04 | 2019-08-13 | 兰州大学 | 一种同时激活氧化磷酸化通路和抑制糖酵解途径的激活剂及其应用 |
CN111039910A (zh) * | 2019-12-31 | 2020-04-21 | 云南大学 | 一种光引发的合成3-芳基黄酮或香豆素类化合物的方法及应用 |
GB202104122D0 (en) * | 2021-03-24 | 2021-05-05 | Floratek Pharma Ag | Compounds and their use |
CN115624546A (zh) * | 2022-09-29 | 2023-01-20 | 南方医科大学第三附属医院(广东省骨科研究院) | 5-羟基黄酮在治疗骨关节炎药物中的用途及其缓释剂的制备 |
US20240300913A1 (en) * | 2023-03-09 | 2024-09-12 | A-Chembio Co., Ltd | Flavone derivative and use thereof for improving pulmonary fibrosis |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3549662A (en) * | 1967-10-12 | 1970-12-22 | Takeda Chemical Industries Ltd | Derivatives of baicalein |
FR2598414B1 (fr) * | 1985-11-12 | 1988-10-14 | Centre Nat Rech Scient | Composition pharmaceutique contenant de l'hispiduline ou un derive et utilisation de ces composes dans la preparation de compositions anti-asthmatiques |
JPH0729920B2 (ja) * | 1987-02-14 | 1995-04-05 | キツセイ薬品工業株式会社 | 骨粗鬆症治療剤 |
JPS6450877A (en) * | 1987-08-20 | 1989-02-27 | Ichimaru Pharcos Inc | Oxygen radical catching and removing agent |
WO1993023033A1 (en) * | 1992-05-11 | 1993-11-25 | Tsumura & Co. | Apoptosis inducer |
GB9317071D0 (en) * | 1993-08-17 | 1993-09-29 | Univ Strathclyde | Flavonoids |
WO1996031206A2 (en) * | 1995-04-07 | 1996-10-10 | Warner-Lambert Company | Flavones and coumarins as agents for the treatment of atherosclerosis |
JPH09176009A (ja) * | 1995-12-27 | 1997-07-08 | Inahata Koryo Kk | 新規な抗変異原剤及び抗変異原性作用物質 |
US6224872B1 (en) * | 1997-07-31 | 2001-05-01 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Composition |
WO2001030342A1 (en) * | 1999-10-20 | 2001-05-03 | Board Of Trustees Of Southern Illinois University | Flavones as inducible nitric oxide synthase inhibitors, cyclooxygenase-2 inhibitors and potassium channel activators |
US6541613B2 (en) * | 2000-12-15 | 2003-04-01 | Uyrex Corporation | Isoflavone derivatives |
-
2003
- 2003-10-22 CA CA002502975A patent/CA2502975A1/en not_active Abandoned
- 2003-10-22 US US10/531,506 patent/US8138165B2/en not_active Expired - Fee Related
- 2003-10-22 AU AU2003282999A patent/AU2003282999A1/en not_active Abandoned
- 2003-10-22 EP EP03774931A patent/EP1556031A4/en not_active Withdrawn
- 2003-10-22 MX MXPA05004247A patent/MXPA05004247A/es not_active Application Discontinuation
- 2003-10-22 WO PCT/US2003/033578 patent/WO2004037193A2/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO2004037193A2 (en) | 2004-05-06 |
CA2502975A1 (en) | 2004-05-06 |
EP1556031A4 (en) | 2009-03-25 |
EP1556031A2 (en) | 2005-07-27 |
AU2003282999A1 (en) | 2004-05-13 |
WO2004037193A3 (en) | 2005-02-17 |
US20060142211A1 (en) | 2006-06-29 |
US8138165B2 (en) | 2012-03-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |