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MXPA05004247A - Cromonas y derivados de cromona y usos de los mismos. - Google Patents

Cromonas y derivados de cromona y usos de los mismos.

Info

Publication number
MXPA05004247A
MXPA05004247A MXPA05004247A MXPA05004247A MXPA05004247A MX PA05004247 A MXPA05004247 A MX PA05004247A MX PA05004247 A MXPA05004247 A MX PA05004247A MX PA05004247 A MXPA05004247 A MX PA05004247A MX PA05004247 A MXPA05004247 A MX PA05004247A
Authority
MX
Mexico
Prior art keywords
chromones
chromone derivatives
present
derivatives
disorders
Prior art date
Application number
MXPA05004247A
Other languages
English (en)
Inventor
S C Wu Edwin
Original Assignee
Jenken Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jenken Biosciences Inc filed Critical Jenken Biosciences Inc
Publication of MXPA05004247A publication Critical patent/MXPA05004247A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/28Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
    • C07D311/30Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)

Abstract

La presente invencion se refiere a las cromonas, los nuevos derivados de cromona, y las formulaciones farmaceuticas que contienen los mismos, y los metodos de uso de los mismos. Los usos de la presente invencion incluyen, pero no estan limitados a, el uso para la prevencion o tratamiento de choque septico, dano a organos y otros trastornos. Los compuestos descritos en la presente pueden ser formas de sales y tambien compuestos solubles en agua.
MXPA05004247A 2002-10-22 2003-10-22 Cromonas y derivados de cromona y usos de los mismos. MXPA05004247A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US42030602P 2002-10-22 2002-10-22
US45377103P 2003-03-11 2003-03-11
PCT/US2003/033578 WO2004037193A2 (en) 2002-10-22 2003-10-22 Chromones and chromone derivatives and uses thereof

Publications (1)

Publication Number Publication Date
MXPA05004247A true MXPA05004247A (es) 2005-10-18

Family

ID=32179793

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA05004247A MXPA05004247A (es) 2002-10-22 2003-10-22 Cromonas y derivados de cromona y usos de los mismos.

Country Status (6)

Country Link
US (1) US8138165B2 (es)
EP (1) EP1556031A4 (es)
AU (1) AU2003282999A1 (es)
CA (1) CA2502975A1 (es)
MX (1) MXPA05004247A (es)
WO (1) WO2004037193A2 (es)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6884783B2 (en) 2002-05-03 2005-04-26 Unigen Pharmaceuticals, Inc. 7-Hydroxy chromones as potent antioxidants
US20060134015A1 (en) 2004-12-22 2006-06-22 Trivedi Harsh M Methods for use of oral care compositions containing free-B-ring flavonoid anti-oxidants
CN101171241A (zh) * 2005-03-11 2008-04-30 密执安州立大学董事会 抗细胞凋亡的bcl-2家族成员的色烯-4-酮抑制剂及其应用
GB0509956D0 (en) * 2005-05-16 2005-06-22 Danisco Method
TWI454261B (zh) * 2007-01-09 2014-10-01 Unigen Inc 作為治療劑之色酮類
EP2478901A3 (en) * 2007-02-14 2012-11-14 Mars Incorporated Neurogenic compounds
CN101062029B (zh) * 2007-05-21 2010-05-19 中国药科大学 汉黄芩素在制备治疗胃癌的药物中的应用
KR100898330B1 (ko) 2007-09-12 2009-05-20 건국대학교 산학협력단 항암성을 갖는 새로운 플라보노이드 유도체 7-o-(3-벤질옥시프로필)-5,4' -o-디메틸-아피제닌, 그 제법 및 그것을 포함하는 항암 조성물
WO2009129372A1 (en) * 2008-04-18 2009-10-22 Shenogen Pharma Group Ltd. Compounds and methods for treating estrogen receptor-related diseases
US9895344B2 (en) 2008-07-25 2018-02-20 Emory University Treating various disorders with 7,8-dihydroxyflavone and derivatives thereof
US20100189653A1 (en) * 2008-10-10 2010-07-29 Wendye Robbins Pyrone analogs for therapeutic treatment
CN101486715B (zh) * 2009-02-09 2013-01-23 沈阳药科大学 噁嗪类化合物及其抗血小板聚集的用途
CN102993147B (zh) * 2009-02-09 2015-09-09 沈阳药科大学 4-色酮及4-色满酮类化合物和用途
US20100222421A1 (en) * 2009-02-27 2010-09-02 National Defense Medical Center Usage of Baicalein in the Preparation of a Pharmaceutical Composition for the Treatment of Traumatic Brain Injury
JP2012525331A (ja) * 2009-04-27 2012-10-22 リメリック バイオファーマ, インコーポレイテッド 治療的処置のためのリン酸化ピロン類似体
CN103965172A (zh) * 2009-09-11 2014-08-06 盛诺基医药科技有限公司 治疗雌激素受体相关疾病的化合物及其方法
US8759548B2 (en) 2010-02-12 2014-06-24 N30 Pharmaceuticals, Inc. S-nitrosoglutathione reductase inhibitors
JP5639665B2 (ja) 2010-02-12 2014-12-10 エヌサーティー・ファーマシューティカルズ・インコーポレーテッド S−ニトロソグルタチオンレダクターゼのクロモン阻害剤
EP2579870B1 (en) 2010-06-09 2018-02-14 Emory University Trkb agonists and methods of use
CA2807199C (en) * 2010-07-27 2020-07-07 Trustees Of Boston University Flavonoid-derived aryl hydrocarbon receptor modulators useful in the treatment of cancer
WO2012066330A1 (en) 2010-11-17 2012-05-24 Heptares Therapeutics Limited Compounds useful as a2a receptor inhibitors
CN102516301B (zh) * 2011-11-28 2016-08-03 江苏天地人和药业有限公司 用于治疗的汉黄芩素衍生物
US9593125B2 (en) 2012-07-27 2017-03-14 Emory University Heterocyclic flavone derivatives, compositions, and methods related thereto
WO2015116460A1 (en) * 2014-01-28 2015-08-06 Virginia Commonwealth University 2-substituted-5-hydroxy-4h-chromen-4-ones as novel ligands for the serotonin receptor 2b (5-ht2b)
WO2017146309A1 (ko) 2016-02-22 2017-08-31 (주)오스티오뉴로젠 유파틸린의 상피간엽이행 억제 활성을 이용한 섬유증 예방 및 치료용 약제학적 조성물로서의 새로운 용도
WO2017156520A1 (en) * 2016-03-11 2017-09-14 H. Lee Moffitt Cancer Center And Research Institute, Inc. Icariin and icaritin derivatives
CN110115712A (zh) * 2019-07-04 2019-08-13 兰州大学 一种同时激活氧化磷酸化通路和抑制糖酵解途径的激活剂及其应用
CN111039910A (zh) * 2019-12-31 2020-04-21 云南大学 一种光引发的合成3-芳基黄酮或香豆素类化合物的方法及应用
GB202104122D0 (en) * 2021-03-24 2021-05-05 Floratek Pharma Ag Compounds and their use
CN115624546A (zh) * 2022-09-29 2023-01-20 南方医科大学第三附属医院(广东省骨科研究院) 5-羟基黄酮在治疗骨关节炎药物中的用途及其缓释剂的制备
US20240300913A1 (en) * 2023-03-09 2024-09-12 A-Chembio Co., Ltd Flavone derivative and use thereof for improving pulmonary fibrosis

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3549662A (en) * 1967-10-12 1970-12-22 Takeda Chemical Industries Ltd Derivatives of baicalein
FR2598414B1 (fr) * 1985-11-12 1988-10-14 Centre Nat Rech Scient Composition pharmaceutique contenant de l'hispiduline ou un derive et utilisation de ces composes dans la preparation de compositions anti-asthmatiques
JPH0729920B2 (ja) * 1987-02-14 1995-04-05 キツセイ薬品工業株式会社 骨粗鬆症治療剤
JPS6450877A (en) * 1987-08-20 1989-02-27 Ichimaru Pharcos Inc Oxygen radical catching and removing agent
WO1993023033A1 (en) * 1992-05-11 1993-11-25 Tsumura & Co. Apoptosis inducer
GB9317071D0 (en) * 1993-08-17 1993-09-29 Univ Strathclyde Flavonoids
WO1996031206A2 (en) * 1995-04-07 1996-10-10 Warner-Lambert Company Flavones and coumarins as agents for the treatment of atherosclerosis
JPH09176009A (ja) * 1995-12-27 1997-07-08 Inahata Koryo Kk 新規な抗変異原剤及び抗変異原性作用物質
US6224872B1 (en) * 1997-07-31 2001-05-01 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Composition
WO2001030342A1 (en) * 1999-10-20 2001-05-03 Board Of Trustees Of Southern Illinois University Flavones as inducible nitric oxide synthase inhibitors, cyclooxygenase-2 inhibitors and potassium channel activators
US6541613B2 (en) * 2000-12-15 2003-04-01 Uyrex Corporation Isoflavone derivatives

Also Published As

Publication number Publication date
WO2004037193A2 (en) 2004-05-06
CA2502975A1 (en) 2004-05-06
EP1556031A4 (en) 2009-03-25
EP1556031A2 (en) 2005-07-27
AU2003282999A1 (en) 2004-05-13
WO2004037193A3 (en) 2005-02-17
US20060142211A1 (en) 2006-06-29
US8138165B2 (en) 2012-03-20

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