TN2014000500A1 - Dimethyl-benzoic acid compounds - Google Patents

Dimethyl-benzoic acid compounds

Info

Publication number: TN2014000500A1
Authority: TN; Tunisia
Prior art keywords: dimethyl; benzoic acid; acid compounds; compounds; och
Prior art date: 2012-06-29

Application number

TN2014000500A

Other languages

English (en)

Inventor

Maria-Jesus Blanco-Pillado

Tatiana Natali Vetman

Matthew Joseph Fisher

Steven Lee Kuklish

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2012-06-29

Filing date

2014-11-28

Publication date

2016-03-30

2014-11-28 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

2016-03-30 Publication of TN2014000500A1 publication Critical patent/TN2014000500A1/fr

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/42—Oxygen atoms attached in position 3 or 5
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/113—Spiro-condensed systems with two or more oxygen atoms as ring hetero atoms in the oxygen-containing ring

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Rheumatology (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Orthopedic Medicine & Surgery (AREA)
Engineering & Computer Science (AREA)
Pain & Pain Management (AREA)
Physical Education & Sports Medicine (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Plural Heterocyclic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Pyrrole Compounds (AREA)

TN2014000500A 2012-06-29 2014-11-28 Dimethyl-benzoic acid compounds TN2014000500A1 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US201261665956P	2012-06-29	2012-06-29
US201361778969P	2013-03-13	2013-03-13
PCT/US2013/046685 WO2014004230A1 (fr)	2012-06-29	2013-06-20	Composés acide diméthyl-benzoïque

Publications (1)

Publication Number	Publication Date
TN2014000500A1 true TN2014000500A1 (en)	2016-03-30

Family

ID=48746667

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
TN2014000500A TN2014000500A1 (en)	2012-06-29	2014-11-28	Dimethyl-benzoic acid compounds

Country Status (41)

Country	Link
US (2)	US8642768B2 (fr)
EP (1)	EP2867218B1 (fr)
JP (1)	JP6114824B2 (fr)
KR (1)	KR101634032B1 (fr)
CN (1)	CN104334540B (fr)
AP (1)	AP4063A (fr)
AR (1)	AR091431A1 (fr)
AU (1)	AU2013280779B2 (fr)
BR (1)	BR112014029551A2 (fr)
CA (1)	CA2875572C (fr)
CL (1)	CL2014003537A1 (fr)
CO (1)	CO7160064A2 (fr)
CR (1)	CR20140554A (fr)
CY (1)	CY1118830T1 (fr)
DK (1)	DK2867218T3 (fr)
DO (1)	DOP2014000286A (fr)
EA (1)	EA025531B1 (fr)
ES (1)	ES2623099T3 (fr)
GT (1)	GT201400289A (fr)
HK (1)	HK1203936A1 (fr)
HR (1)	HRP20170540T1 (fr)
HU (1)	HUE032398T2 (fr)
IL (1)	IL236218A (fr)
IN (1)	IN2014MN02356A (fr)
JO (1)	JO3221B1 (fr)
LT (1)	LT2867218T (fr)
ME (1)	ME02655B (fr)
MX (1)	MX347476B (fr)
MY (1)	MY172860A (fr)
NZ (1)	NZ701894A (fr)
PE (1)	PE20150185A1 (fr)
PH (1)	PH12015500008A1 (fr)
PL (1)	PL2867218T3 (fr)
PT (1)	PT2867218T (fr)
RS (1)	RS55756B1 (fr)
SG (1)	SG11201408629QA (fr)
SI (1)	SI2867218T1 (fr)
TN (1)	TN2014000500A1 (fr)
TW (1)	TWI572597B (fr)
WO (1)	WO2014004230A1 (fr)
ZA (1)	ZA201408631B (fr)

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US20110015221A1 (en) *	2003-12-23	2011-01-20	Pierre Fabre Medicament	Pharmaceutical composition of vinflunine which is intended for parenteral administration preparation method thereof and use of same
TWI572597B (zh) *	2012-06-29	2017-03-01	美國禮來大藥廠	二甲基－苯甲酸化合物
EP2765128A1 (fr) *	2013-02-07	2014-08-13	Almirall, S.A.	Benzamides substitués présentant une activité vis-à-vis de récepteurs EP4
TWI636046B (zh)	2013-05-17	2018-09-21	美國禮來大藥廠	苯氧基乙基二氫－１ｈ－異喹啉化合物
WO2015094912A1 (fr)	2013-12-17	2015-06-25	Eli Lilly And Company	Composés d'acide diméthylbenzoïque
JP6618530B2 (ja) *	2014-09-09	2019-12-11	バイエルファーマアクチエンゲゼルシャフト	置換ｎ，２−ジアリールキノリン−４−カルボキサミドおよび抗炎症剤としてのその使用
CR20180323A (es)	2015-11-20	2018-08-06	Idorsia Pharmaceuticals Ltd	Derivados de indol n-sustituídos como moduladores de los receptores de pge2
CA3059273A1 (fr) *	2017-04-10	2018-10-18	Bayer Aktiengesellschaft	N-arylethyl-2-arylquinoleine-4-carboxamides substitues et leur utilisation
TWI770157B (zh) *	2017-04-10	2022-07-11	德商拜耳廠股份有限公司	經取代之n-芳基乙基-2-胺基喹啉-4-甲醯胺及其用途
PT3625222T (pt)	2017-05-18	2021-10-07	Idorsia Pharmaceuticals Ltd	Derivados de fenilo como moduladores do recetor de pge2
ES2887041T3 (es)	2017-05-18	2021-12-21	Idorsia Pharmaceuticals Ltd	Derivados de pirimidina como moduladores del receptor de PGE2
US11325899B2 (en)	2017-05-18	2022-05-10	Idorsia Pharmaceuticals Ltd	Benzofurane and benzothiophene derivatives as PGE2 receptor modulators
EP3625223B1 (fr)	2017-05-18	2021-08-11	Idorsia Pharmaceuticals Ltd	Dérivés de pyrimidine
PH12019502562B1 (en)	2017-05-18	2024-06-14	Idorsia Pharmaceuticals Ltd	N-substituted indole derivatives
US20230390303A1 (en)	2020-11-13	2023-12-07	Ono Pharmaceutical Co., Ltd.	Cancer treatment by combination of ep4 antagonist and immune checkpoint inhibitor

Family Cites Families (9)

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Publication number	Priority date	Publication date	Assignee	Title
IT1270615B (it)	1994-07-14	1997-05-07	Smithkline Beecham Farma	Uso di derivati di chinolina
JP2000355551A (ja) *	1999-06-15	2000-12-26	Nikken Chem Co Ltd	医薬組成物
CN1863790A (zh)	2003-09-22	2006-11-15	欧洲凯尔特公司	用于治疗疼痛的治疗药
EP1723132A1 (fr)	2004-02-12	2006-11-22	Asterand Uk Limited	Agonistes des recepteurs ep sb 2 /sb
EP2035376B1 (fr) *	2006-06-12	2014-08-27	Merck Canada Inc.	Dérivés amide de l'indoline en tant que ligands du récepteur ep4
US8030489B2 (en) *	2007-03-26	2011-10-04	Astellas Pharma Inc.	Ornithine derivative
WO2012004293A2 (fr)	2010-07-08	2012-01-12	Bayer Cropscience Ag	Associations de substances actives insecticides et fongicides
JP2014514257A (ja)	2011-03-03	2014-06-19	ユニバーシテーテデスザールランデス	選択的１７ベータ−ヒドロキシステロイドデヒドロゲナーゼ２型阻害剤としてのビアリール誘導体
TWI572597B (zh) *	2012-06-29	2017-03-01	美國禮來大藥廠	二甲基－苯甲酸化合物

2013
- 2013-06-11 TW TW102120796A patent/TWI572597B/zh not_active IP Right Cessation
- 2013-06-13 AR ARP130102078 patent/AR091431A1/es unknown
- 2013-06-13 JO JOP/2013/0178A patent/JO3221B1/ar active
- 2013-06-20 BR BR112014029551A patent/BR112014029551A2/pt not_active IP Right Cessation
- 2013-06-20 DK DK13734249.9T patent/DK2867218T3/en active
- 2013-06-20 MY MYPI2014703973A patent/MY172860A/en unknown
- 2013-06-20 RS RS20170231A patent/RS55756B1/sr unknown
- 2013-06-20 ME MEP-2017-83A patent/ME02655B/fr unknown
- 2013-06-20 CN CN201380030138.XA patent/CN104334540B/zh not_active Expired - Fee Related
- 2013-06-20 KR KR1020147036136A patent/KR101634032B1/ko active IP Right Grant
- 2013-06-20 US US13/922,277 patent/US8642768B2/en not_active Expired - Fee Related
- 2013-06-20 AP AP2014008165A patent/AP4063A/en active
- 2013-06-20 EP EP13734249.9A patent/EP2867218B1/fr active Active
- 2013-06-20 WO PCT/US2013/046685 patent/WO2014004230A1/fr active Application Filing
- 2013-06-20 IN IN2356MUN2014 patent/IN2014MN02356A/en unknown
- 2013-06-20 JP JP2015520305A patent/JP6114824B2/ja active Active
- 2013-06-20 MX MX2014015952A patent/MX347476B/es active IP Right Grant
- 2013-06-20 HU HUE13734249A patent/HUE032398T2/en unknown
- 2013-06-20 LT LTEP13734249.9T patent/LT2867218T/lt unknown
- 2013-06-20 ES ES13734249.9T patent/ES2623099T3/es active Active
- 2013-06-20 AU AU2013280779A patent/AU2013280779B2/en not_active Ceased
- 2013-06-20 PL PL13734249T patent/PL2867218T3/pl unknown
- 2013-06-20 SI SI201330576A patent/SI2867218T1/sl unknown
- 2013-06-20 PE PE2014002531A patent/PE20150185A1/es active IP Right Grant
- 2013-06-20 NZ NZ701894A patent/NZ701894A/en not_active IP Right Cessation
- 2013-06-20 CA CA2875572A patent/CA2875572C/fr not_active Expired - Fee Related
- 2013-06-20 PT PT137342499T patent/PT2867218T/pt unknown
- 2013-06-20 EA EA201492140A patent/EA025531B1/ru not_active IP Right Cessation
- 2013-06-20 SG SG11201408629QA patent/SG11201408629QA/en unknown
- 2013-12-04 US US14/096,469 patent/US8933098B2/en not_active Expired - Fee Related
2014
- 2014-11-24 ZA ZA2014/08631A patent/ZA201408631B/en unknown
- 2014-11-28 TN TN2014000500A patent/TN2014000500A1/fr unknown
- 2014-12-03 CR CR20140554A patent/CR20140554A/es unknown
- 2014-12-11 IL IL236218A patent/IL236218A/en active IP Right Grant
- 2014-12-17 DO DO2014000286A patent/DOP2014000286A/es unknown
- 2014-12-17 GT GT201400289A patent/GT201400289A/es unknown
- 2014-12-18 CO CO14278424A patent/CO7160064A2/es unknown
- 2014-12-26 CL CL2014003537A patent/CL2014003537A1/es unknown
2015
- 2015-01-05 PH PH12015500008A patent/PH12015500008A1/en unknown
- 2015-05-07 HK HK15104360.7A patent/HK1203936A1/xx not_active IP Right Cessation
2017
- 2017-04-03 HR HRP20170540TT patent/HRP20170540T1/hr unknown
- 2017-04-12 CY CY20171100435T patent/CY1118830T1/el unknown

Also Published As

Publication number	Publication date
HUE032398T2 (en)	2017-09-28
AR091431A1 (es)	2015-02-04
US20140005222A1 (en)	2014-01-02
CO7160064A2 (es)	2015-01-15
US20140094491A1 (en)	2014-04-03
MX347476B (es)	2017-04-27
ZA201408631B (en)	2017-04-26
BR112014029551A2 (pt)	2017-06-27
AU2013280779B2 (en)	2015-09-10
EA025531B1 (ru)	2017-01-30
IL236218A (en)	2017-12-31
CR20140554A (es)	2015-02-04
TW201410665A (zh)	2014-03-16
MY172860A (en)	2019-12-12
PE20150185A1 (es)	2015-02-13
JP6114824B2 (ja)	2017-04-12
LT2867218T (lt)	2017-04-25
PH12015500008B1 (en)	2015-03-02
DOP2014000286A (es)	2015-01-31
EA201492140A1 (ru)	2015-10-30
EP2867218A1 (fr)	2015-05-06
KR20150013335A (ko)	2015-02-04
ES2623099T3 (es)	2017-07-10
MX2014015952A (es)	2015-07-17
CN104334540B (zh)	2016-03-16
PH12015500008A1 (en)	2015-03-02
WO2014004230A1 (fr)	2014-01-03
GT201400289A (es)	2015-05-28
SI2867218T1 (sl)	2017-04-26
JO3221B1 (ar)	2018-03-08
IL236218A0 (en)	2015-02-01
DK2867218T3 (en)	2017-05-01
EP2867218B1 (fr)	2017-02-22
CL2014003537A1 (es)	2015-04-24
TWI572597B (zh)	2017-03-01
PT2867218T (pt)	2017-04-19
JP2015522589A (ja)	2015-08-06
CA2875572A1 (fr)	2014-01-03
IN2014MN02356A (fr)	2015-08-14
HK1203936A1 (en)	2015-11-06
PL2867218T3 (pl)	2017-07-31
KR101634032B1 (ko)	2016-06-27
NZ701894A (en)	2016-09-30
US8642768B2 (en)	2014-02-04
US8933098B2 (en)	2015-01-13
SG11201408629QA (en)	2015-01-29
RS55756B1 (sr)	2017-07-31
AU2013280779A1 (en)	2014-11-27
AP2014008165A0 (en)	2014-12-31
AP4063A (en)	2017-03-09
ME02655B (fr)	2017-06-20
HRP20170540T1 (hr)	2017-06-16
CA2875572C (fr)	2016-03-22
CN104334540A (zh)	2015-02-04
CY1118830T1 (el)	2018-01-10

Publication	Publication Date	Title
PH12015500008B1 (en)	2015-03-02	Dimethyl-benzoic acid compounds
UA110338C2 (xx)	2015-12-25	Хімічні сполуки
IN2013MN02014A (fr)	2015-06-12
MX2013012760A (es)	2014-03-12	Nuevos compuestos y composiciones para la inhibicion de nampt.
PH12013500412A1 (en)	2013-04-22	Novel compounds and compositions for the inhibition of nampt
IN2014MN01521A (fr)	2015-05-01
MX343561B (es)	2016-11-09	Compuestos de imidazolpiridazina.
PH12012501650B1 (en)	2018-11-07	Heterocyclic compound
MX342310B (es)	2016-09-26	Compuestos de tiazolopirimidina.
MX349548B (es)	2017-08-02	Compuestos de tienopirimidina.
IN2014CN04449A (fr)	2015-09-04
UA113086C2 (xx)	2016-12-12	Піразольні сполуки як інгібітори sglt1
MX369470B (es)	2019-11-08	Medios y método para el tratamiento de tumores sólidos.
SA516371323B1 (ar)	2018-04-24	مركبات بيرازول فلورو فينيل
CY1121116T1 (el)	2019-12-11	Νεα μεθοδος για την συνθεση αγομελατινης
MX359399B (es)	2018-09-27	Inhibidores de 17alfa-hidroxilasa/c17-20-liasa.
PH12012502247A1 (en)	2013-02-04	Novel processes
IN2015DN02514A (fr)	2015-09-11
EA201300794A1 (ru)	2014-02-28	Новый способ синтеза агомелатина
IN2013MU03015A (fr)	2015-07-17
UA113764C2 (xx)	2017-03-10	Сполуки диметилбензойної кислоти
WO2013175498A3 (fr)	2013-12-19	Nouveau composé à base d'amidoamine et de glycérol et son procédé de préparation
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