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SI0765308T1 - Enzyme inhibitors - Google Patents

Enzyme inhibitors

Info

Publication number
SI0765308T1
SI0765308T1 SI9530412T SI9530412T SI0765308T1 SI 0765308 T1 SI0765308 T1 SI 0765308T1 SI 9530412 T SI9530412 T SI 9530412T SI 9530412 T SI9530412 T SI 9530412T SI 0765308 T1 SI0765308 T1 SI 0765308T1
Authority
SI
Slovenia
Prior art keywords
enzyme inhibitors
protecting group
amidino
intermediates
chem
Prior art date
Application number
SI9530412T
Other languages
English (en)
Slovenian (sl)
Inventor
Harold Francis Hodson
Richard M.J. Palmer
David Alan Sawyer
Richard Graham Knowles
Karl Witold Franzmann
Martin James Drysdale
Steven Smith
Patricia Ifeyinwa Davies
Helen Alice Rebecca Clark
Barry George Shearer
Original Assignee
The Wellcome Foundation Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9509774.7A external-priority patent/GB9509774D0/en
Application filed by The Wellcome Foundation Limited filed Critical The Wellcome Foundation Limited
Publication of SI0765308T1 publication Critical patent/SI0765308T1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/60Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • C07C317/44Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • C07C317/48Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
SI9530412T 1994-06-15 1995-06-14 Enzyme inhibitors SI0765308T1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP94304314 1994-06-15
GBGB9509774.7A GB9509774D0 (en) 1995-05-15 1995-05-15 Enzyme inhibitors
PCT/GB1995/001378 WO1995034534A1 (en) 1994-06-15 1995-06-14 Enzyme inhibitors
EP95924405A EP0765308B1 (en) 1994-06-15 1995-06-14 Enzyme inhibitors

Publications (1)

Publication Number Publication Date
SI0765308T1 true SI0765308T1 (en) 2000-08-31

Family

ID=26137155

Family Applications (2)

Application Number Title Priority Date Filing Date
SI9530412T SI0765308T1 (en) 1994-06-15 1995-06-14 Enzyme inhibitors
SI9530645T SI0957087T1 (en) 1994-06-15 1995-06-14 Intermediates useful in the preparation of enzyme inhibitors

Family Applications After (1)

Application Number Title Priority Date Filing Date
SI9530645T SI0957087T1 (en) 1994-06-15 1995-06-14 Intermediates useful in the preparation of enzyme inhibitors

Country Status (29)

Country Link
US (2) US5889056A (da)
EP (2) EP0765308B1 (da)
JP (2) JP2989010B2 (da)
KR (1) KR100430207B1 (da)
CN (1) CN1070849C (da)
AT (2) ATE191470T1 (da)
AU (1) AU692892B2 (da)
BR (1) BR9507995A (da)
CA (1) CA2192668A1 (da)
CY (2) CY2238B1 (da)
DE (2) DE69516141T2 (da)
DK (2) DK0765308T3 (da)
ES (2) ES2145282T3 (da)
FI (1) FI965019A (da)
GR (1) GR3033746T3 (da)
HK (1) HK1003935A1 (da)
HU (1) HUT77407A (da)
IL (2) IL114142A (da)
IS (1) IS4384A (da)
MX (1) MX9606136A (da)
MY (1) MY115437A (da)
NO (1) NO308655B1 (da)
NZ (1) NZ289157A (da)
PT (2) PT765308E (da)
RU (1) RU2162841C2 (da)
SI (2) SI0765308T1 (da)
TW (1) TW442453B (da)
WO (1) WO1995034534A1 (da)
ZA (1) ZA954940B (da)

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Also Published As

Publication number Publication date
JP2000026402A (ja) 2000-01-25
IL114142A0 (en) 1995-10-31
EP0957087A2 (en) 1999-11-17
JPH10506371A (ja) 1998-06-23
CY2455B1 (en) 2005-06-03
CN1155276A (zh) 1997-07-23
NZ289157A (en) 1998-03-25
DE69516141D1 (de) 2000-05-11
IS4384A (is) 1996-11-13
NO308655B1 (no) 2000-10-09
SI0957087T1 (en) 2003-04-30
NO965379D0 (no) 1996-12-13
WO1995034534A1 (en) 1995-12-21
EP0957087A3 (en) 2000-12-20
DK0765308T3 (da) 2000-09-11
US5889056A (en) 1999-03-30
CN1070849C (zh) 2001-09-12
FI965019A0 (fi) 1996-12-13
EP0765308A1 (en) 1997-04-02
HUT77407A (hu) 1998-04-28
IL114142A (en) 2000-02-17
EP0765308B1 (en) 2000-04-05
HK1003935A1 (en) 1998-11-13
ZA954940B (en) 1996-12-17
CA2192668A1 (en) 1995-12-21
RU2162841C2 (ru) 2001-02-10
DE69529101D1 (de) 2003-01-16
PT957087E (pt) 2003-04-30
ATE191470T1 (de) 2000-04-15
AU2891795A (en) 1996-01-05
USRE39576E1 (en) 2007-04-17
PT765308E (pt) 2000-09-29
EP0957087B1 (en) 2002-12-04
BR9507995A (pt) 1997-08-05
IL128717A0 (en) 2000-01-31
JP2989010B2 (ja) 1999-12-13
DE69529101T2 (de) 2003-11-13
AU692892B2 (en) 1998-06-18
GR3033746T3 (en) 2000-10-31
HU9603454D0 (en) 1997-02-28
KR100430207B1 (ko) 2004-07-19
MX9606136A (es) 1998-06-30
ES2145282T3 (es) 2000-07-01
DK0957087T3 (da) 2003-03-24
FI965019A (fi) 1996-12-13
NO965379L (no) 1996-12-13
DE69516141T2 (de) 2000-10-19
JP3614711B2 (ja) 2005-01-26
TW442453B (en) 2001-06-23
CY2238B1 (en) 2003-07-04
MY115437A (en) 2003-06-30
ATE229001T1 (de) 2002-12-15
ES2189322T3 (es) 2003-07-01

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