SG10202010735PA - Tau-binding antibodies - Google Patents
Tau-binding antibodiesInfo
- Publication number
- SG10202010735PA SG10202010735PA SG10202010735PA SG10202010735PA SG10202010735PA SG 10202010735P A SG10202010735P A SG 10202010735PA SG 10202010735P A SG10202010735P A SG 10202010735PA SG 10202010735P A SG10202010735P A SG 10202010735PA SG 10202010735P A SG10202010735P A SG 10202010735PA
- Authority
- SG
- Singapore
- Prior art keywords
- tau
- binding antibodies
- antibodies
- binding
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/524—CH2 domain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/526—CH3 domain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hospice & Palliative Care (AREA)
- Animal Behavior & Ethology (AREA)
- Psychiatry (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP15175522 | 2015-07-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
SG10202010735PA true SG10202010735PA (en) | 2020-11-27 |
Family
ID=53524640
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10202010735PA SG10202010735PA (en) | 2015-07-06 | 2016-07-05 | Tau-binding antibodies |
Country Status (27)
Country | Link |
---|---|
US (4) | US10287343B2 (es) |
EP (1) | EP3319983A1 (es) |
JP (3) | JP6630426B2 (es) |
KR (1) | KR20180025962A (es) |
CN (1) | CN107849104B (es) |
AR (1) | AR105267A1 (es) |
AU (1) | AU2016289755C1 (es) |
BR (1) | BR112017028102A2 (es) |
CA (1) | CA2991451A1 (es) |
CL (1) | CL2018000043A1 (es) |
CO (1) | CO2017012971A2 (es) |
EA (1) | EA037092B1 (es) |
EC (1) | ECSP18000887A (es) |
HK (1) | HK1246804A1 (es) |
IL (1) | IL256685B (es) |
MA (2) | MA41670A1 (es) |
MX (1) | MX2017015817A (es) |
MY (1) | MY193677A (es) |
PE (1) | PE20180481A1 (es) |
PH (1) | PH12017502207A1 (es) |
SG (1) | SG10202010735PA (es) |
TN (1) | TN2017000539A1 (es) |
TW (1) | TWI745295B (es) |
UA (1) | UA124616C2 (es) |
UY (1) | UY36773A (es) |
WO (1) | WO2017005734A1 (es) |
ZA (1) | ZA201800027B (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
UA126272C2 (uk) | 2015-06-05 | 2022-09-14 | Дженентек, Інк. | Антитіло проти тау-білка та спосіб його застосування |
KR20180025962A (ko) | 2015-07-06 | 2018-03-09 | 유씨비 바이오파마 에스피알엘 | 타우 결합 항체 |
KR20180027566A (ko) | 2015-07-06 | 2018-03-14 | 유씨비 바이오파마 에스피알엘 | 타우 결합 항체 |
WO2018106776A2 (en) | 2016-12-07 | 2018-06-14 | Genentech, Inc. | Anti-tau antibodies and methods of use |
MX2019006334A (es) | 2016-12-07 | 2019-08-01 | Genentech Inc | Anticuerpos antitau y métodos de uso. |
KR20190134997A (ko) | 2017-02-17 | 2019-12-05 | 데날리 테라퓨틱스 인크. | 항-tau 항체 및 이의 사용 방법 |
JP2018139530A (ja) | 2017-02-27 | 2018-09-13 | 帝人ファーマ株式会社 | 認知症治療又は予防のためのヒト化抗体及びその製造方法、並びにそれを用いた認知症治療剤又は予防剤 |
KR102225178B1 (ko) | 2017-10-16 | 2021-03-10 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 항-타우 항체 및 그의 용도 |
US20220017611A1 (en) * | 2018-12-13 | 2022-01-20 | INSERM (Institut National de la Santé et de la Recherche Médicale) | New anti tau svqivykpv epitope single domain antibody |
EP4013772A4 (en) * | 2019-08-13 | 2024-06-05 | Washington University | METHODS FOR DETECTING MTBR-TAU ISOFORMS AND THEIR USE |
JP7399305B2 (ja) | 2020-02-12 | 2023-12-15 | イーライ リリー アンド カンパニー | 抗体または抗原結合フラグメントの結晶化 |
AU2021297873A1 (en) | 2020-06-25 | 2023-02-09 | Merck Sharp & Dohme Llc | High affinity antibodies targeting tau phosphorylated at serine 413 |
WO2023092004A1 (en) | 2021-11-17 | 2023-05-25 | Voyager Therapeutics, Inc. | Compositions and methods for the treatment of tau-related disorders |
WO2024107745A1 (en) * | 2022-11-14 | 2024-05-23 | Washington University | Methods to detect csf mtbr-tau and uses thereof |
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GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
GB8719042D0 (en) | 1987-08-12 | 1987-09-16 | Parker D | Conjugate compounds |
GB8720833D0 (en) | 1987-09-04 | 1987-10-14 | Celltech Ltd | Recombinant dna product |
GB8907617D0 (en) | 1989-04-05 | 1989-05-17 | Celltech Ltd | Drug delivery system |
GB8928874D0 (en) | 1989-12-21 | 1990-02-28 | Celltech Ltd | Humanised antibodies |
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GB9112536D0 (en) | 1991-06-11 | 1991-07-31 | Celltech Ltd | Chemical compounds |
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MY178142A (en) * | 2011-12-20 | 2020-10-05 | Janssen Biotech Inc | Anti-phf-tau antibodies and their uses |
KR20200013072A (ko) | 2012-07-03 | 2020-02-05 | 워싱턴 유니버시티 | Tau에 대한 항체 |
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EA035932B1 (ru) | 2012-12-21 | 2020-09-02 | Байоджен Ма Инк. | Человеческие анти-тау антитела |
CA2874083C (en) * | 2014-12-05 | 2024-01-02 | Universite Laval | Tdp-43-binding polypeptides useful for the treatment of neurodegenerative diseases |
KR20180025962A (ko) | 2015-07-06 | 2018-03-09 | 유씨비 바이오파마 에스피알엘 | 타우 결합 항체 |
KR20180027566A (ko) | 2015-07-06 | 2018-03-14 | 유씨비 바이오파마 에스피알엘 | 타우 결합 항체 |
-
2016
- 2016-07-05 KR KR1020187003689A patent/KR20180025962A/ko not_active Application Discontinuation
- 2016-07-05 JP JP2018500423A patent/JP6630426B2/ja active Active
- 2016-07-05 AU AU2016289755A patent/AU2016289755C1/en active Active
- 2016-07-05 TN TNP/2017/000539A patent/TN2017000539A1/en unknown
- 2016-07-05 EA EA201890172A patent/EA037092B1/ru not_active IP Right Cessation
- 2016-07-05 EP EP16734676.6A patent/EP3319983A1/en active Pending
- 2016-07-05 SG SG10202010735PA patent/SG10202010735PA/en unknown
- 2016-07-05 PE PE2017002750A patent/PE20180481A1/es unknown
- 2016-07-05 MA MA41670A patent/MA41670A1/fr unknown
- 2016-07-05 MA MA042377A patent/MA42377A/fr unknown
- 2016-07-05 MX MX2017015817A patent/MX2017015817A/es unknown
- 2016-07-05 BR BR112017028102A patent/BR112017028102A2/pt active Search and Examination
- 2016-07-05 WO PCT/EP2016/065813 patent/WO2017005734A1/en active Application Filing
- 2016-07-05 MY MYPI2018700043A patent/MY193677A/en unknown
- 2016-07-05 US US15/742,087 patent/US10287343B2/en active Active
- 2016-07-05 UA UAA201711739A patent/UA124616C2/uk unknown
- 2016-07-05 CA CA2991451A patent/CA2991451A1/en active Pending
- 2016-07-05 CN CN201680039795.4A patent/CN107849104B/zh active Active
- 2016-07-06 UY UY0001036773A patent/UY36773A/es not_active Application Discontinuation
- 2016-07-06 AR ARP160102045A patent/AR105267A1/es unknown
- 2016-07-06 TW TW105121455A patent/TWI745295B/zh active
-
2017
- 2017-12-04 PH PH12017502207A patent/PH12017502207A1/en unknown
- 2017-12-18 CO CONC2017/0012971A patent/CO2017012971A2/es unknown
-
2018
- 2018-01-01 IL IL256685A patent/IL256685B/en unknown
- 2018-01-03 ZA ZA2018/00027A patent/ZA201800027B/en unknown
- 2018-01-05 CL CL2018000043A patent/CL2018000043A1/es unknown
- 2018-01-05 EC ECIEPI2018887A patent/ECSP18000887A/es unknown
- 2018-05-10 HK HK18106080.8A patent/HK1246804A1/zh unknown
-
2019
- 2019-05-13 US US16/409,945 patent/US10889640B2/en active Active
- 2019-12-06 JP JP2019220807A patent/JP7100008B2/ja active Active
-
2020
- 2020-12-29 US US17/136,189 patent/US11732034B2/en active Active
-
2022
- 2022-06-30 JP JP2022105415A patent/JP7413448B2/ja active Active
-
2023
- 2023-06-30 US US18/344,945 patent/US20230416350A1/en active Pending
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