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PL374558A1 - Sposoby oczyszczania lewofloksacyny - Google Patents

Sposoby oczyszczania lewofloksacyny

Info

Publication number
PL374558A1
PL374558A1 PL02374558A PL37455802A PL374558A1 PL 374558 A1 PL374558 A1 PL 374558A1 PL 02374558 A PL02374558 A PL 02374558A PL 37455802 A PL37455802 A PL 37455802A PL 374558 A1 PL374558 A1 PL 374558A1
Authority
PL
Poland
Prior art keywords
levofloxacin
purification
methods
Prior art date
Application number
PL02374558A
Other languages
English (en)
Inventor
Valerie Niddam-Hildesheim
Neomi Gershon
Eduard Schwartz
Original Assignee
Teva Pharmaceutical Industries Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/263,192 external-priority patent/US7629458B2/en
Application filed by Teva Pharmaceutical Industries Ltd. filed Critical Teva Pharmaceutical Industries Ltd.
Publication of PL374558A1 publication Critical patent/PL374558A1/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/06Peri-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Epoxy Compounds (AREA)
PL02374558A 2001-11-29 2002-11-27 Sposoby oczyszczania lewofloksacyny PL374558A1 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US33431601P 2001-11-29 2001-11-29
US35493902P 2002-02-11 2002-02-11
US26296502A 2002-10-03 2002-10-03
US10/263,192 US7629458B2 (en) 2001-10-03 2002-10-03 Preparation of levofloxacin and hemihydrate thereof

Publications (1)

Publication Number Publication Date
PL374558A1 true PL374558A1 (pl) 2005-10-31

Family

ID=31892240

Family Applications (1)

Application Number Title Priority Date Filing Date
PL02374558A PL374558A1 (pl) 2001-11-29 2002-11-27 Sposoby oczyszczania lewofloksacyny

Country Status (13)

Country Link
EP (1) EP1460997A4 (pl)
JP (3) JP2005527484A (pl)
CN (1) CN1596256A (pl)
AU (1) AU2002365416A1 (pl)
CA (1) CA2466860A1 (pl)
HR (1) HRP20040546A2 (pl)
HU (1) HUP0500285A3 (pl)
IL (1) IL162172A0 (pl)
IS (1) IS7288A (pl)
MX (1) MXPA04005196A (pl)
NO (1) NO20042731L (pl)
PL (1) PL374558A1 (pl)
WO (1) WO2003045329A2 (pl)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1451194B2 (en) 2001-10-03 2009-12-16 Teva Pharmaceutical Industries Ltd. Preparation of levofloxacin hemihydrate
US20060276463A1 (en) * 2002-12-16 2006-12-07 Sharma Tarun K Pure levofloxacin hemihydrate and processes for preparation thereof
KR100704641B1 (ko) * 2004-07-21 2007-04-06 주식회사유한양행 고순도의 레보플록사신 제조방법
JP2006273718A (ja) * 2005-03-28 2006-10-12 Shiono Chemical Co Ltd レボフロキサシン・1/2水和物の製法
CN1321121C (zh) * 2005-04-21 2007-06-13 浙江医药股份有限公司新昌制药厂 左氧氟沙星制备及后处理方法
US7964723B2 (en) 2008-08-02 2011-06-21 Apeloa-Kangyu And practical process for exclusively producing (S)-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido-[1,2,3,de][1,4]benzoxazine-6-carboxylic acid hemihydrate
CN102070650B (zh) * 2011-01-28 2012-06-27 山东省药品检验所 左氧氟沙星-n-氧化物的制备方法
US20120251685A1 (en) * 2011-04-04 2012-10-04 Martek Biosciences Corporation Oil-in-Water Emulsions Comprising a Polyunsaturated Fatty Acid and Methods of Making the Same
CN105823851A (zh) * 2015-12-15 2016-08-03 浙江海洋学院 一种检测海水中氧氟沙星对映体的方法
CN108218892A (zh) * 2018-03-16 2018-06-29 乐山职业技术学院 一种左氧氟沙星的纯化方法
CN114507242B (zh) * 2022-01-26 2023-05-19 上虞京新药业有限公司 高光学纯度左氧氟沙星的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO166131C (no) * 1985-06-20 1991-06-05 Daiichi Seiyaku Co Analogifremgangsmaate for fremstilling av s(-)-pyridobenzoksazinforbindelser.
US5237060A (en) * 1985-12-10 1993-08-17 Bayer Aktiengesellschaft Process of preparing enantiomerically pure 1,8-bridged 4-quinolone-3-carboxylic acids
TW208013B (pl) * 1990-03-01 1993-06-21 Daiichi Co Ltd
US5521310A (en) * 1992-10-07 1996-05-28 Derivados Del Etilo, S.A. Process to obtain benzoxazines to be used for the synthesis of ofloxazine, levofloxazine and derivatives
KR0125115B1 (ko) * 1994-03-22 1997-12-05 김은영 (-)피페라진 벤즈옥사진 유도체의 제조방법
KR100309871B1 (ko) * 1999-02-24 2001-10-29 윤종용 (-)피리도벤즈옥사진 카르복실산 유도체의 제조방법
EP1451194B2 (en) * 2001-10-03 2009-12-16 Teva Pharmaceutical Industries Ltd. Preparation of levofloxacin hemihydrate

Also Published As

Publication number Publication date
CA2466860A1 (en) 2003-06-05
CN1596256A (zh) 2005-03-16
AU2002365416A1 (en) 2003-06-10
JP2005527484A (ja) 2005-09-15
HRP20040546A2 (en) 2004-10-31
HUP0500285A3 (en) 2009-03-30
WO2003045329A2 (en) 2003-06-05
NO20042731L (no) 2004-06-29
EP1460997A4 (en) 2005-06-15
WO2003045329A3 (en) 2004-02-19
MXPA04005196A (es) 2005-11-23
JP2008007517A (ja) 2008-01-17
HUP0500285A2 (hu) 2005-06-28
IL162172A0 (en) 2005-11-20
IS7288A (is) 2004-06-21
JP2006219496A (ja) 2006-08-24
EP1460997A2 (en) 2004-09-29

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Legal Events

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