PL374558A1 - Methods for the purification of levofloxacin - Google Patents

Methods for the purification of levofloxacin

Info

Publication number: PL374558A1
Authority: PL; Poland
Prior art keywords: levofloxacin; purification; methods
Prior art date: 2001-11-29

Application number

PL02374558A

Other languages

Polish (pl)

Inventor

Valerie Niddam-Hildesheim

Neomi Gershon

Eduard Schwartz

Original Assignee

Teva Pharmaceutical Industries Ltd.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-11-29

Filing date

2002-11-27

Publication date

2005-10-31

2002-10-03 Priority claimed from US10/263,192 external-priority patent/US7629458B2/en

2002-11-27 Application filed by Teva Pharmaceutical Industries Ltd. filed Critical Teva Pharmaceutical Industries Ltd.

2005-10-31 Publication of PL374558A1 publication Critical patent/PL374558A1/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/06—Peri-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Communicable Diseases (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Epoxy Compounds (AREA)

PL02374558A 2001-11-29 2002-11-27 Methods for the purification of levofloxacin PL374558A1 (en)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US33431601P	2001-11-29	2001-11-29
US35493902P	2002-02-11	2002-02-11
US26296502A	2002-10-03	2002-10-03
US10/263,192 US7629458B2 (en)	2001-10-03	2002-10-03	Preparation of levofloxacin and hemihydrate thereof

Publications (1)

Publication Number	Publication Date
PL374558A1 true PL374558A1 (en)	2005-10-31

Family

ID=31892240

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL02374558A PL374558A1 (en)	2001-11-29	2002-11-27	Methods for the purification of levofloxacin

Country Status (13)

Country	Link
EP (1)	EP1460997A4 (en)
JP (3)	JP2005527484A (en)
CN (1)	CN1596256A (en)
AU (1)	AU2002365416A1 (en)
CA (1)	CA2466860A1 (en)
HR (1)	HRP20040546A2 (en)
HU (1)	HUP0500285A3 (en)
IL (1)	IL162172A0 (en)
IS (1)	IS7288A (en)
MX (1)	MXPA04005196A (en)
NO (1)	NO20042731L (en)
PL (1)	PL374558A1 (en)
WO (1)	WO2003045329A2 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1451194B2 (en)	2001-10-03	2009-12-16	Teva Pharmaceutical Industries Ltd.	Preparation of levofloxacin hemihydrate
US20060276463A1 (en) *	2002-12-16	2006-12-07	Sharma Tarun K	Pure levofloxacin hemihydrate and processes for preparation thereof
KR100704641B1 (en) *	2004-07-21	2007-04-06	주식회사유한양행	Methods for the preparation of levofloxacin having a high purity
JP2006273718A (en) *	2005-03-28	2006-10-12	Shiono Chemical Co Ltd	Method for producing levofloxacin-1/2 hydrate
CN1321121C (en) *	2005-04-21	2007-06-13	浙江医药股份有限公司新昌制药厂	Preparation and post-treatment method of levofloxacin
US7964723B2 (en)	2008-08-02	2011-06-21	Apeloa-Kangyu	And practical process for exclusively producing (S)-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido-[1,2,3,de][1,4]benzoxazine-6-carboxylic acid hemihydrate
CN102070650B (en) *	2011-01-28	2012-06-27	山东省药品检验所	Preparation method for levofloxacin-N-oxide
US20120251685A1 (en) *	2011-04-04	2012-10-04	Martek Biosciences Corporation	Oil-in-Water Emulsions Comprising a Polyunsaturated Fatty Acid and Methods of Making the Same
CN105823851A (en) *	2015-12-15	2016-08-03	浙江海洋学院	Detection method for ofloxacin enantiomer in seawater
CN108218892A (en) *	2018-03-16	2018-06-29	乐山职业技术学院	A kind of purification process of lavo-ofloxacin
CN114507242B (en) *	2022-01-26	2023-05-19	上虞京新药业有限公司	Preparation method of levofloxacin with high optical purity

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NO166131C (en) *	1985-06-20	1991-06-05	Daiichi Seiyaku Co	ANALOGUE PROCEDURE FOR THE PREPARATION OF S (-) - PYRIDOBENZOKSAZINE COMPOUNDS.
US5237060A (en) *	1985-12-10	1993-08-17	Bayer Aktiengesellschaft	Process of preparing enantiomerically pure 1,8-bridged 4-quinolone-3-carboxylic acids
TW208013B (en) *	1990-03-01	1993-06-21	Daiichi Co Ltd
US5521310A (en) *	1992-10-07	1996-05-28	Derivados Del Etilo, S.A.	Process to obtain benzoxazines to be used for the synthesis of ofloxazine, levofloxazine and derivatives
KR0125115B1 (en) *	1994-03-22	1997-12-05	김은영	Process for preparing piperazinyl quinolone derivatives
KR100309871B1 (en) *	1999-02-24	2001-10-29	윤종용	Process for Preparing (-)Pyridobenzoxazine Carboxylic Acid Derivatives
EP1451194B2 (en) *	2001-10-03	2009-12-16	Teva Pharmaceutical Industries Ltd.	Preparation of levofloxacin hemihydrate

2002
- 2002-11-27 CN CNA028236440A patent/CN1596256A/en active Pending
- 2002-11-27 MX MXPA04005196A patent/MXPA04005196A/en not_active Application Discontinuation
- 2002-11-27 IL IL16217202A patent/IL162172A0/en unknown
- 2002-11-27 JP JP2003546834A patent/JP2005527484A/en active Pending
- 2002-11-27 HU HU0500285A patent/HUP0500285A3/en unknown
- 2002-11-27 EP EP02791339A patent/EP1460997A4/en not_active Withdrawn
- 2002-11-27 WO PCT/US2002/038182 patent/WO2003045329A2/en active Application Filing
- 2002-11-27 CA CA002466860A patent/CA2466860A1/en not_active Abandoned
- 2002-11-27 AU AU2002365416A patent/AU2002365416A1/en not_active Abandoned
- 2002-11-27 PL PL02374558A patent/PL374558A1/en not_active Application Discontinuation
2004
- 2004-05-27 IS IS7288A patent/IS7288A/en unknown
- 2004-06-15 HR HR20040546A patent/HRP20040546A2/en not_active Application Discontinuation
- 2004-06-29 NO NO20042731A patent/NO20042731L/en not_active Application Discontinuation
2006
- 2006-05-01 JP JP2006127862A patent/JP2006219496A/en not_active Withdrawn
2007
- 2007-08-22 JP JP2007216178A patent/JP2008007517A/en active Pending

Also Published As

Publication number	Publication date
CA2466860A1 (en)	2003-06-05
CN1596256A (en)	2005-03-16
AU2002365416A1 (en)	2003-06-10
JP2005527484A (en)	2005-09-15
HRP20040546A2 (en)	2004-10-31
HUP0500285A3 (en)	2009-03-30
WO2003045329A2 (en)	2003-06-05
NO20042731L (en)	2004-06-29
EP1460997A4 (en)	2005-06-15
WO2003045329A3 (en)	2004-02-19
MXPA04005196A (en)	2005-11-23
JP2008007517A (en)	2008-01-17
HUP0500285A2 (en)	2005-06-28
IL162172A0 (en)	2005-11-20
IS7288A (en)	2004-06-21
JP2006219496A (en)	2006-08-24
EP1460997A2 (en)	2004-09-29

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GB0209222D0 (en)	2002-06-05	Purification process
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GB0113300D0 (en)	2001-07-25	Purification process
IL164788A0 (en)	2005-12-18	Process for the preparation of 3-isochromanone
AU2002366004A1 (en)	2003-06-10	Process for the purification of contaminated oils
GB0116022D0 (en)	2001-08-22	Purification process
IL159508A0 (en)	2004-06-01	Apparatus for the purification of water
PL368905A1 (en)	2005-04-04	Process for the preparation of beta-ionylideneacetaldehyde
SI1395580T1 (en)	2005-04-30	Method for the purification of triazolylmethylepoxides
AU2003248597A1 (en)	2003-09-16	The purification of 2-methoxy-5-trifluoromethoxybenzaldehyde
AU2002316900A1 (en)	2002-12-03	Method for the purification of triazolylmethylepoxides

Legal Events

Date	Code	Title	Description
2011-01-31	REFS	Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)