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KR20080011287A - 세포 증식 질환을 분석하기 위한 방법 및 핵산 - Google Patents

세포 증식 질환을 분석하기 위한 방법 및 핵산 Download PDF

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KR20080011287A
KR20080011287A KR1020077026458A KR20077026458A KR20080011287A KR 20080011287 A KR20080011287 A KR 20080011287A KR 1020077026458 A KR1020077026458 A KR 1020077026458A KR 20077026458 A KR20077026458 A KR 20077026458A KR 20080011287 A KR20080011287 A KR 20080011287A
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위르겐 디스틀러
토마스 힐드만
랄프 레스케
캐시 로프톤-데이
파비안 모델
마티아스 슈스터
앤드류 슬레드지스키
시아오링 송
레이모 테츠너
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Abstract

본 발명의 요지는 간세포 증식 질환을 검출, 또는 검출 및 구분하거나, 또는 직장결장 세포 증식 질환을 검출, 또는 검출 및 구분하기 위한 방법, 핵산 및 키트를 제공한다. 특정 요지는 그의 메틸화 패턴이 상기 부류의 질환의 검출 및 구별을 개선시키는데 상당한 효용을 갖고, 따라서 환자의 진단 및 치료를 개선시킬 수 있는 게놈 서열을 개시 및 제공한다.
세포 증식 질환, 간암, 직장결장암, 메틸화 패턴.

Description

세포 증식 질환을 분석하기 위한 방법 및 핵산{METHODS AND NUCLEIC ACIDS FOR ANALYSES OF CELLULAR PROLIFERATIVE DISORDERS}
본 발명은 정상적인 상태와 비교하여 질환 상태에서 변화된 발현 패턴을 나타내는 게놈 DNA 서열에 관한 것이다. 특정 실시양태는 세포 증식 질환을 검출하거나 또는 검출 및 구별하는데 유용한 신규 방법, 핵산, 핵산 어레이 및 키트를 제공한다. 바람직하게는, 세포 증식 질환을 검출 및 진단하기 위한 방법, 핵산, 핵산 어레이 및 키트를, 암, 구체적으로는 직장결장암 및/또는 간암을 진단하는데 사용한다.
관련 출원에 대한 교차 참조
본원은 2005년 4월 15일자로 출원된 미국 특허 가출원 제 60/672,242 호; 2005년 5월 2일자로 출원된 미국 특허 가출원 제 60/676,997호; 2005년 7월 8일자로 출원된 미국 특허 가출원 제 60/697,521 호; 2005년 8월 1일자로 출원된 미국 특허 가출원 제 60/704,860 호; 2005년 8월 17일자로 출원된 미국 특허 가출원 제 60/709,318 호; 2005년 10월 4일자로 출원된 미국 특허 가출원 제 60/723,602 호; 및 2006년 3월 30일자로 출원된 미국 특허 가출원 제 60/787,402 호에 기초한 우선 권을 주장하며, 상기 출원은 모두 본원에 참고로 인용된다.
서열 목록
특허법 제 1.52(e)(5) 항에 따른 서열 목록은 1.82MB 텍스트 파일로서 콤팩트 디스크(1/1)로 제공되었으며, 상기 파일은 명칭이 "47675-187 Sequence Listing.txt"이고 본원에 참고로 인용된다.
암의 발병 및 진단. 암은 미국내 사망의 두번째 주된 요인이다. 환자 순응성, 민감도 및 스크리닝의 용이성 면에서 현행 스크리닝 방법을 개선한다면 사망률을 상당히 개선할 수 있다. 암을 진단하기 위해 현재 권장되는 방법은 흔히 비싸고 광역 개체군 스크리닝 시험으로서 적용하기에 적합하지 않다.
간세포암(HCC)은 전세계적으로 네번째로 가장 통상적인 암이고, 이의 발병률은 북미에서의 100,000명당 2.1명에서 중국에서의 100,000명당 80명까지에 이른다. 미국에서는, 2005년에 새롭게 진단되는 경우가 17,550건이고 이 질환으로 인해 15,420명이 사망할 것으로 예측된다. HCC(간세포암 또는 원발성 간암)의 진단 평가에서는 통상적으로 간의 초음파, 알파 태아단백 수준 및 통상적인 CT 스캔을 수득하지만, 이들은 흔히 너무 민감하지 못하여 다병소성의 작은 병변을 검출하지 못하고 치료 계획을 세우기 어렵다.
미국에서는, 직장결장암의 연간 발병률이 약 150,000명이고, 매년 직장결장 암으로 56,600명이 사망한다. 일반적인 개체군에서 질장결장암의 평생 위험도는 약 5 내지 6%이다. 최근 수년동안 결장암의 스크리닝 및 조기 검출에 집중적으로 노력을 기울였지만, 현재까지 대부분의 경우가 주위 또는 타 장기로 전이된 진행된 상태에서 진단된다. 치료 옵션은 수술 및 보조적 또는 고식적 화학요법을 포함하지만, 대부분의 환자는 수개월내에 암이 진행되어 사망한다. 결장암 발생의 근간이 되는 분자 변화를 확인하면 이들 환자의 전반적인 불량한 예후 판정을 개선할 수 있는 새로운 모니터링, 스크리닝, 진단 및 치료 옵션을 개발하는데 도움을 줄 수 있다.
미국 암 협회에 따른 직장결장 스크리닝의 현행 지침은 50세 이상의 평균 위험도의 개인에서 스크리닝하기 위한 5가지 상이한 옵션중 하나를 이용한다. 이들 옵션은 1) 매년 대변 잠혈 검사(FOBT), 2) 매 5년마다 가요성 s상 결장경 검사, 3) 매년 FOBT 및 매 5년마다 가요성 s상 결장경 검사, 4) 매 5년마다 이중 조영 바륨 관장(DCBE) 또는 5) 매 10년마다 결장경 검사를 포함한다. 이들 시험 절차가 의료계에서 널리 수용되고 있기는 하지만, 직장결장암의 광범위한 스크리닝은 실현되지 못하고 있다. 환자 순응성은 이들 절차에 수반되는 불편한 또는 부자연스러움 때문에 제한적인 사용의 주된 인자이다. FOBT 검사는 비-침습성 절차이지만 검사 전 3 내지 5일동안 식사 및 다른 제한을 요구한다. 이 검사의 민감도 수준도 매 실행시마다 폭넓게 변화하여 직장결장 선암종에 대해 매우 낮다. 선종 검출을 위한 민감도 측정치는 대부분의 선종이 출혈을 나타내지 않기 때문에 더 낮다. 대조적으로, s상 결장경 검사 및 결장경 검사 같은 더욱 침습성인 절차의 민감도는 결장 내 강을 직접 보기 때문에 상당히 높다. 이들 기법의 효능을 무작위적으로 평가하지는 않았지만, 환자군-대조군 연구로부터의 데이터 및 국내 폴립 연구(미국)로부터의 데이터를 사용하여 선종성 폴립을 제거하면 CRC 발병률이 76 내지 90% 감소되는 것으로 밝혀졌다. s상 결장경 검사는 결장의 왼쪽만 볼 수 있어서 오른쪽 결장에서의 병변은 검출되지 않는다는 단점이 있다. 양쪽을 다 보는 절차는 비싸고, 하제를 필요로 하며, 이환 및 사망 위험이 증가된다. 직장결장암의 일반적인 광범위한 스크리닝이 통상적으로 되기 전에 증가된 민감도, 특이성, 사용의 용이성 및 감소된 비용을 갖는 개선된 검사가 명백히 필요하다.
초기 직장결장암 검출은 일반적으로 무증상 개인에서 매년 수행되는 대변 잠혈 검사(FOBT)에 기초한다. 미국 암 협회를 비롯한 몇몇 건강관리 기구에 의해 적합화된 현행 권장사항은 50세부터 대변 잠혈 검사를 시작하여 더 이상 스크리닝으로부터의 이점이 없을 때까지 매년 반복할 것을 요구한다. 양성 FOBT 시에는 비싼 침습성 절차인 장의 결장경 검사로 이어진다(5,000회 시험당 1회의 심각한 합병증 비율). 환원 헤마틴 양성 대변을 갖는 환자중 12%만이 결장경 검사에서 암 또는 대형 폴립을 갖는 것으로 진단된다. 다수의 연구는 FOBT 스크리닝이 암-관련 사망률 또는 전체적인 생존율을 개선하지 않음을 보여준다. 잠혈 검사에 대한 순응성은 불량하고; 개체군의 20% 미만이 권장된 대로 FOBT를 시도하거나 이행한다. FOBT가 적절하게 수행되는 경우, 환자는 3회의 연속적인 장 운동으로부터의 대변 샘플을 수집한다. 환자가 식사 지침을 준수하고 잠복 위장관 출혈을 유도하는 것으로 알려진 약물을 피하는 동안 샘플을 수득한다. 실제로, 내과의는 흔히 환자를 적절하게 지도하지 못하고, 환자는 흔히 절차를 준수하지 못하며, 일부 환자는 대변 샘플을 모으는 과제가 어렵거나 불쾌한 것으로 판단하는 바, 매년 잠혈 검사의 순응성은 불량하다. 검사 민감도 및 특이성이 현행 방법보다 개선될 수 있다면, 검사 빈도를 감소시킬 수 있고, 연속적인 샘플의 수집을 피할 수 있으며, 식사 및 약물 스케쥴 변경도 없애고 환자 순응성을 향상시키게 된다. 순응성의 문제를 조합하면, 결장암을 검출하기 위한 FOBT의 민감도 및 특이성은 불량하다. 불량한 시험 특이성은 불필요한 결장경 검사를 하게 만들어, 결장암 스크리닝에 상당한 비용을 부가한다.
FOBT의 특이성은 기껏해야 96%인 것으로 계산되었고, 민감도는 43%(선종) 및 50%(직장결장 암종)이다. 상표명 '인슈어(InSure™)'로 제조되는 것과 같은 면역분석 FOBT를 사용하여 민감도를 개선시킬 수 있는데, 이는 77%(선종) 및 88.9%(직장결장 암종)의 개선된 민감도를 갖는다.
분자 질환 마커. 분자 질환 마커는 다른 유형의 마커에 비해 몇 가지 이점을 제공하는데, 한가지 이점은 매우 작은 크기의 샘플 및/또는 조직 구조가 유지되지 못한 샘플조차도 상당히 효율적으로 분석할 수 있다는 것이다. 지난 10년 내에, 정상 세포와 결장 암종 사이에서 다수의 유전자가 차별적으로 발현된 것으로 밝혀졌다. 그러나, 결장 암종의 진단에 충분한 것으로 밝혀진 단일 마커 또는 마커 조합은 없었다. 고차원 mRNA에 기초한 방법이 최근 상이한 종양 유형 및 양성 병변과 악성 병변을 구별하는 더욱 우수한 수단을 제공할 수 있는 것으로 밝혀졌다. 그러나, 임상 환경에서의 통상적인 진단 도구로서의 이의 적용은 mRNA의 극단 적인 불안정성, 특정 자극(예: 샘플 수거) 후 급속하게 발생하는 발현 변화 및 가장 중요하게는 분석에 필요한 다량의 mRNA(이는 종종 통상적인 생검으로부터 수득될 수 없음)에 의해 방해된다[립슈츠(Lipshutz, R. J.) 등, Nature Genetics 21:20-24, 1999; 보텔(Bowtell, D. D. L.) Nature genetics suppl. 21:25-32, 1999].
FOBT의 민감도 및 특이성을 추가로 개선하기 위하여 생물학적 마커의 사용이 제안되었으며, 이러한 검사의 예는 20%(선종) 및 52%(직장결장 암종)의 민감도 및 두 경우 모두에서 95%의 특이성을 갖는 프레젠-플러스(PreGen-Plus™) 대변 분석법[이그잭트 사이언시즈(EXACT Sciences)에서 구입]을 포함한다. 이 검사에서는 결장 신생물의 발생에 수반되는 23개의 DNA 돌연변이의 존재를 분석한다. 결장암 마커로서 DNA 메틸화를 사용하는 것은 알려져 있다. 예를 들어, 사비오니(Sabbioni) 등[Molecular Diagnosis 7:201-207, 2003]은 결장 암종 환자의 98%에서 말초혈액중 TPEF, HIC1, DAPK 및 MGMT로 이루어진 유전자 패널의 과메틸화를 검출하였다. 그러나, 이는 이러한 검사의 특이성이 또한 충분히 높아야 하기 때문에 시판가능한 검사의 적합한 기초를 제공할 뿐이다.
직장결장 발병의 현행 모델은 선종의 단계적 진행(이는 형성이상의 발생 및 마지막으로 침습성 암의 징후를 포함함)을 선호한다. 이 선종-암종 순서의 근간이 되는 분자 변화는 종양 억제 유전자(APC, p53, DCC)의 유전학적 및 후성학적 변화, 종양 유전자(K-ras)의 활성화 및 DNA 불일치 교정 유전자의 불활성화를 포함한다. 최근, 추가적인 분자 변화 및 유전자 결함이 밝혀졌다. 그러므로, Wnt 신호전달 경로의 활성화는 APC 유전자의 돌연변이를 포함할 뿐만 아니라 β-카테닌 돌연변이로부터 야기될 수도 있다. 뿐만 아니라, TGF-β 신호전달 경로의 변화는 그의 신호 변환자 SMAD4 및 SMAD2와 함께 결장암의 발생에 관련되어 있다.
결장의 선종 및 암종의 병인 및 이들의 유전자 및 분자 변화에 대한 이해에서의 최근의 진보에도 불구하고, 전이 발생의 근간이 되는 유전학적 및 후성학적 변화는 덜 알려져 있다. 그러나, 세포외 매트릭스의 침습 및 단백질 분해, 및 혈관 기저막의 침윤이 인테그린 수용체 부류의 일원, 카드헤린, 면역글로불린 상과, 라미닌 결합 단백질 및 CD44 수용체 같은 유착 단백질를 포함한다는 것은 일반적으로 널리 받아들여지고 있다. 유착과는 별도로, 전이 형성 과정은 또한 혈관 형성의 유도 및 조절(VEGF, bFGF), 세포 증식의 유도(EGF, HGF, IGF) 및 단백질 분해 효소의 활성화(MMP, TIMP, uPAR) 및 세포자멸사의 억제(Bcl-2, Bcl-X)도 포함한다. 더욱 최근에는, 다른 군에서 전이성 병변에서의 유전자 및 분자 변화를 원발성 직장결장암에서 발견되는 변화와 비교하였다. 따라서, 클리프(Kleeff) 등은 원발성 직장결장암 및 전이성 직장결장암 둘 다에서 암 억제 유전자 후보인 DOC-2의 손실을 보고하였다. 뿐만 아니라, 자우버(Zauber) 등은 42가지 직장결장암의 씨리즈에서 원발성 암에서의 Ki-ras 돌연변이가 42쌍의 원발성 병변 및 동시 전이성 병변 모두에서 동일하였음을 보고하였다. 유사하게, 39쌍의 암종 및 동시 전이에서 APC 위치에서의 이형성의 손실이 동일하였다. 상기 저자는 Ki-ras 및 APC 유전자의 경우 전이의 유전자 변화가 원발성 직장결장암과 동일한 것으로 결론지었다. 그러나, 다른 군에서는 원발성 암에는 존재하지 않는 전이성 결장암에서의 유전자 및 분자 변화를 발견하였다. 따라서, 직장결장 전이에서는 염색체 3p의 LOH의 발생이 보고되었다. 또한, 비교용 게놈 하이브리드 형성을 이용하여, 전이성 병변에 독특한 몇 가지 변화(-9q, -11q 및 -17q)를 간 전이에서 발견하였다.
CpG 섬 메틸화. 돌연변이와는 별도로, CpG 섬의 이상 메틸화가 이전에 다양한 암의 병인과 연결된 특정 유전자의 전사 침묵화를 야기하는 것으로 밝혀졌다. CpG 섬은 CpG 다이뉴클레오타이드가 풍부한 짧은 서열이고, 모든 인간 유전자의 약 50%의 5' 영역에서 통상적으로 발견될 수 있다. 이들 섬에서의 시토신의 메틸화는 유전자 발현의 상실을 야기하고, X 염색체의 불활성화 및 게놈 각인에서 보고된 바 있다.
최근, 몇몇 군에서는 직장결장암의 다양한 유전자의 메틸화를 분석하였고, 특히 p16INK4, p14ARF, p15INK4b, MGMT, hMLH1, GSTP1, DAPK, CDH1, TIMP-3 및 APC에 대해 프로모터 메틸화에 의한 전사 침묵화를 보고하였다. 따라서, 특정 유전자의 돌연변이성 불활성화와는 별도로, 이들 유전자의 과메틸화도 이 질환의 발병에 크게 기여한다.
최근 수년간, 결장암에서 메틸화된 몇 가지 유전자를 MS-APPCR에 의해 확인하였다. 이 유전자 군은 특히 결장암에서 흔히 메틸화되고 MS-APPCR 방법을 이용하여 두 상이한 군으로 독립적으로 확인된 TPEF/HPP1을 포함한다[예컨대, 영(Young J), 비덴(Biden KG), 심스(Simms LA), 허가드(Huggard P), 카라마틱(Karamatic R), 아이어(Eyre HJ), 서덜랜드(Sutherland GR), 헤라쓰(Herath N), 바커(Barker M), 앤더슨(Anderson GJ), 피츠패트릭(Fitzpatrick DR), 램(Ramm GA), 재스(Jass JR), 리게트(Leggett BA), HPP1: a transmembrane protein-encoding gene commonly methylated in colorectal polyps and cancers. Proc Natl Acad Sci USA 98:265-270, 2001 참조].
다원적 접근법. 암 진단은 전통적으로 단일 분자 마커(예컨대, 유전자 돌연변이, 높아진 PSA 수준)의 검출에 의존해왔다. 불행하게도, 암은 단일 마커가 전형적으로 검출하지 못하거나 질환의 다수의 형태를 구별하지 못하는 질환이다. 그러므로, 단일 마커만을 인식하는 분석법은 한정된 예견치를 나타내는 것으로 밝혀졌다. 본 발명의 기본 요지는 메틸화에 기초한 암 진단 및 이들 질환의 스크리닝, 진단 및 치료용 모니터링이 선택된 복수개의 마커를 사용함으로써 단일 마커 분석법을 이용하는 당해 분야의 기술 상태를 크게 개선시키리라는 것이다. 다중 분석법은 암이 단순한 질환이 아니기 때문에 암 진단에 특히 잘 맞으며, 이 다원적 "패널" 접근법은 세포학적으로나 임상적으로나 암의 이질적인 특성과 조화된다.
메틸화에 기초한 진단 시험에 대한 패널 접근법의 성공적인 실행을 위한 핵심은 질환 상태의 특징을 결정하고 구별해낼 수 있는 최적화된 마커 패널의 디자인 및 개발이다. 본 발명은 복수개의 특히 효율적이고 독특한 유전자 패널, 특히 높은 민감도, 특이성 및/또는 예견치로 결장 세포 증식 질환의 검출을 가능케 하는 패널의 일원중 하나 또는 조합의 메틸화 분석을 기재한다. 의학 시험의 발전. 임의의 의학적 스크리닝 또는 진단 시험의 두 핵심적인 평가 척도는 그의 민감도 및 특이성인데, 이는 이 시험이 얼마나 잘 수행되어 예외 없이 또한 표적 질환을 갖지 않는 개체를 잘못 포함하지 않으면서 질환에 걸린 모든 개체를 정확하게 검출하는 지(예견치)를 측정한다. 역사적으로, 다수의 진단 시험은 불량한 민감도 및 특이성으로 인해 비난을 받았다.
올바른 양성(TP) 결과는 시험이 양성이고 질병이 존재하는 경우이다. 잘못된 양성(FP) 결과는 시험이 양성이지만 질병이 존재하지 않는 경우이다. 올바른 음성(TN) 결과는 시험이 음성이고 질병이 존재하지 않는 경우이다. 잘못된 음성(FN) 결과는 시험이 음성이지만 질병이 존재하는 경우이다. 이와 관련하여, 민감도=TP/(TP+FN); 특이성=TN/(FP+TN); 예견치=TP/(TP+FP)이다.
민감도는 시험되는 개체에서 표적 질환을 올바르게 검출하는 시험의 능력의 척도이다. 불량한 민감도를 갖는 시험은 높은 잘못된 음성(즉, 질환을 갖지만 특정 질환을 갖지 않는 것으로 잘못 확인된 개체) 비율을 생성시킨다. 잘못된 음성의 잠재적인 위험은 질환에 걸린 개체가 어느 기간동안 진단 및 치료를 받지 않은 채로 지내고 그 기간동안 질환이 치료가 이루어지더라도 덜 효과적일 수 있는 더욱 후기 단계로 진행될 수 있는 것이다. 낮은 민감도를 갖는 시험의 예는 HIV의 단백질에 기초한 혈액 시험이다. 이 유형의 시험은 질환이 완전히 확립되고 상당수의 바이러스가 혈류에 침입할 때까지 바이러스의 존재를 검출할 수 없기 때문에 낮은 민감도를 나타낸다. 대조적으로, 높은 민감도를 갖는 시험의 예는 폴리머라제 연쇄 반응(PCR)을 이용한 바이러스-로딩 검출이다. 이 유형의 시험은 매우 소량의 바이러스를 검출할 수 있기 때문에 높은 민감도를 달성한다. 진단 누락의 영향력이 높은 경우에 높은 민감도가 특히 중요하다.
반면, 특이성은 질환 상태를 갖지 않는 환자를 정확하게 확인하는 시험의 능 력의 척도이다. 불량한 특이성을 갖는 시험은 높은 잘못된 양성(즉, 질환을 갖는 것으로 잘못 확인된 개체) 비율을 생성시킨다. 잘못된 양성의 단점은 환자가 위험, 감정적 및 재정적 스트레스를 받으면서 환자의 건강에 악영향을 끼칠 수 있는 불필요한 의료 절차를 받도록 만드는 것이다. 높은 특이성을 갖는 진단 시험을 개발하기 어렵게 만드는 질환의 특징은 특히 암에서의 질환 메카니즘이 흔히 복수개의 유전자 및 단백질을 포함하는 것이다. 또한, 특정 단백질은 질환 상태와 무관한 이유로 높아질 수 있다. 높은 특이성을 갖는 시험의 예는 p53 돌연변이를 검출할 수 있는 유전자에 기초한 시험이다. 특이성은 추가적인 진단 절차 또는 추가적인 의료 개입에 수반되는 비용 또는 위험이 매우 높은 경우에 중요하다.
당해 분야에서의 현저한 요구. 암의 개선된 스크리닝 및 조기 검출이 당해 분야에서 현저하게 요구된다는 것은 일반적으로 받아들여지고 있는 사실이다. 예로서, 결장암 스크리닝 특이성을 높일 수 있다면, 불필요한 결장경 검사를 하게 만드는 잘못된 양성 시험 결과의 문제가 감소되어 비용을 절감하고 안전성을 개선하게 된다.
일반적으로 암의 발병, 더욱 구체적으로는 현행 직장결장 및 간세포 세포 증식 질환 스크리닝 방법에 수반되는 단점으로 보아, 당해 분야에서는 현재 이용가능한 시험에 덧붙여 또는 현재 이용가능한 시험에 대한 대안으로서 암, 특히 결장암의 조기 검출을 위한 개선된 방법에 대한 요구가 상당하다.
본 발명의 유전자의 배경 기술. 인간 셉틴(Septin) 9 유전자(MLL 셉틴-유사 융합 단백질, MLL 셉틴-유사 융합 단백질 MSF-A, SIpa, 에셉틴, Msf, 셉틴-유사 단 백질/난소/유방 셉틴(Ov/Br 셉틴) 및 셉틴 D1으로도 알려짐)는 콘티그 AC068594.15.1.168501 내에서 염색체 17q25 상에 위치하고, 셉틴 유전자 부류의 일원이다. 도 1은 셉틴 9 유전자의 앙상블(Ensambl) 설명을 제공하고, 4가지 전사 변이형, 즉 셉틴 9 변이형 및 Q9HC74 변이형(이는 셉틴 9 전사물의 절단된 형태임)을 보여준다. 서열 번호:1은 셉틴 9 및 Q9HC74 전사물의 영역 및 프로모터 영역을 포함하는 상기 유전자의 서열을 제공한다. 서열 번호:2 및 서열 번호:3은 각각 셉틴 9 및 Q9HC74 전사물의 CpG가 풍부한 프로모터 영역의 서열을 제공하는 이들의 부속-영역(sub-region)이다.
셉틴 유전자 부류의 일원은 소포 운송으로부터 세포질 분열에 이르는 여러 세포 기능에 연관되어 있는 것으로 인정되어 왔다. 셉틴 9의 작용을 중단시키면 세포 분열이 불완전해진다. 설카(Surka, M.C.), 상(Tsang, C.W.) 및 트림블(Trimble, W.S.)의 문헌[Mol Biol Cell, 13:3532-45 (2002)] 참조. 셉틴 9 및 다른 단백질은 프로토-종양 유전자 MLL의 융합 파트너인 것으로 밝혀져 종양 발생에서의 역할을 암시한다. 오사카(Osaka, M.), 롤리(Rowley, J.D.) 및 젤레즈닉-리(Zeleznik-Le, N.J.)의 문헌[PNAS, 96:6428-6433 (1999)] 참조. 뷰로우즈(Burrows) 등은 난소암에서의 셉틴 9 유전자의 여러 아이소형의 발현에 대한 심도있는 연구를 보고하였고, 다양한 전사물의 조직 특이적 발현을 밝혀내었다. 뷰로우즈(Burrows, J.F.), 챈듈로이(Chanduloy) 등의 문헌[S.E.H. Journal of Pathology, 201:581-588 (2003)] 참조.
7000개가 넘는 정상 조직 및 종양 조직에 대한 최근의 연구(우선일 이후에 공개된 종래 기술)는 다수의 종양 조직에서 셉틴 9 아이소형의 일관된 과-발현이 존재함을 나타낸다. 스콧(Scott, M.), 하일랜드(Hyland, P.L.) 등의 문헌[Oncogene, 24:4688-4700 (2005)] 참조. 상기 저자들은 RNA 전사 과정의 변화가 상이한 단백질 생성물의 조절을 제어하고 이들 변화된 단백질 아이소형의 수준이 악성 종양에서의 유전자의 역할에 대한 해답을 제공할 수 있다고 생각한다.
FN1 유전자로부터 전사된 MSF(이동 촉진 인자) 단백질도 발암에 연루되어 있으나(WO 99/31233 호 참조), 이 단백질은 본원의 주제가 아니고 현재 셉틴 9/MSF 유전자 및 이들의 전사 생성물과 관련된 것으로 알려져 있지 않음에 주목해야 한다.
상기 인용된 참조문헌으로부터 상기 유전자를 종양 발생과 관련짓는 생물학적 메카니즘이 밝혀지지 않고 있음을 알 수 있다. WO 2004/07441 호에서는, 유전자의 증가된 복제 수 및 과-발현이 암의 마커이고 상기 관찰에 따라 암의 진단 및 치료를 위한 수단을 제공한다고 주장한다. 따라서, WO 2004/07441 호는 본 발명의 방법 및 핵산과 공통되는 특징을 가장 많이 갖고 동일한 분야(암 진단)에 관련되어 있기 때문에 가장 근접한 종래 기술이다. 본 발명과 WO 2004/07441 호 사이의 주된 차이점은 본 발명이 최초로 유전자 셉틴 9의 저-발현(under-expression)이 암과 관련있음을 밝혔다는 것이다. 더욱 구체적으로, 이는 메틸화 분석에 의해 예증된다. 발현과 DNA 메틸화 사이의 상관관계 및 DNA 메틸화를 결정하는 방법은 당해 분야에 공지되어 있다(WO 99/28498 호 참조). 그럼에도 불구하고, 특히 WO 2004/07441 호가 암에 대한 가능한 치료법으로서 상기 발현을 보다 낮은 수준으로 조정함을 기재하기 때문에, 당해 분야의 숙련자는 저-발현이 암의 발생과 관련 있음을 알지 못하였다.
서열 번호:28은 비트로넥틴(VTN, OMIM 193190, 수납 번호 NM_000638) 및 SARM 유전자(스터릴 알파 및 히트/아마딜로 모티프-함유 단백질, OMIM 607732)의 겹쳐지는 프로모터 영역에서 염색체 17q 상에 위치하는 CpG가 풍부한 서열을 제공한다.
VTN 유전자는 시험관 내에서 동물 세포의 부착 및 전개를 촉진시키고 보체 C5b-9 착체에 의해 세포 용해를 억제하며 혈액 응고에서 항트롬빈 III-트롬빈 작용을 조정하는 75-kD 당단백(혈청 전개 인자 또는 보체 S-단백질이라고도 불림)을 코딩한다. 결장암 세포에서는 더 높은 비트로넥틴 발현이 관찰되었다[Exp Cell Res. 1994년 9월; 214(1):303-12]. 뿐만 아니라, 이 유전자의 발현은 암 세포의 진행 및 침습에 연관되어 있다. 종양에서는 VTN이 활성화되고 특이적인 펩타이드에 의해 비트로넥틴 수용체를 차단하면 종양 크기를 감소시키는 것으로 제안된다[블뢰멘달(Bloemendal HJ), 드 보어(de Boer HC), 쿱(Koop EA), 반 동겐(van Dongen AJ), 골드슈메딩(Goldschmeding R), 랜드맨(Landman WJ), 록텐버그(Logtenberg T), 게빙크(Gebbink MF), 뵈스트(Voest EE), Cancer Immunol Immunother. 2004년 9월; 53(9):799-808; 하이어(Haier J), 골드만(Goldmann U), 호츠(Hotz B), 런켈(Runkel N), 케일홀즈(Keilholz U), Clin Exp Metastasis, 2002; 19(8):665-72].
SARM 단백질은 690개의 아미노산으로 이루어지고, 짧은 히트/아마딜로(HEAT/armadillo) 반복 서열에 의해 둘러싸인 65개 아미노산의 멸균 알파(SAM) 도메인을 함유한다. 노던 블롯(Northern blot) 분석은 SARM 안티센스 RNA가 조직의 공급원 또는 대사 가능성과는 무관하게 암 세포주에서 높아진 수준으로 검출될 수 있음을 보여주었다[밍크(Mink, M.); 포겔그렌(Fogelgren, B.); 올쥬스키(Olszewski, K.); 머로이(Maroy, P.); 시자(Csiszar, K.), Genomics 74:234-244, 2001]. 상기 연구는 또한 단백질-코딩 SARM 전사물이 연구된 하나의 전립선종 세포주에서만 발현되었음을 입증하였다.
서열 번호:24는 유전자 포크헤드(Forkhead) 전사 인자 L2 유전자(FOXL2, 뇌하수체 포크헤드 인자, OMIM 605597) 하류의 염색체 3q23 상에 위치하는 CpG가 풍부한 서열을 제공한다. 서열 번호:1은 지금까지 어떠한 유형의 암과도 연관되지 않았다. FOXL2 코딩 영역은 포유동물 사이에서 고도로 보존된다. 면역조직화학적 증거는 FOXL2가 눈꺼풀 및 태아 및 성인 난소 난포 세포에서 특이적으로 발현되는 핵 단백질임을 나타낸다. FOXL2가 난소 체세포 분화 및 추가로 난포 발생 및/또는 유지에서 일익을 담당할 수 있는 것으로 제안된다[J. Med. Genet. 39:916-922, 2002].
또한, FOXL2 유전자에서의 돌연변이는 눈꺼풀 및 난소에 영향을 끼치는 증후군인 실눈증/처짐/역 눈구석 주름 증후군(BPES)과 관련되어 있다[Am. J. Hum. Genet. 72:478-487, 2003; Hum. Mutat. 24:189-193, 2004]. FOXL2 유전자는 지금까지 암과 관련되지 않았으나, FOX 부류의 다른 일원은 발암에 연루되었다. FOXA1 유전자는 식도암 및 폐암에서 증폭 및 과발현되고, FOXM1 유전자는 소닉 헤지호그(Sonic Hedgehog)(SHH) 경로에 의한 전사 조절 때문에 췌장암 및 기저세포 암종 에서 상향 조절된다.
서열 번호:27은 염색체 14q 상에 위치하는 Six6(호메오박스 단백질 SIX6) 유전자의 일부를 나타내고, 이명은 호메오도메인 단백질 OPTX2, 옵틱 호메오박스 2, OPTX2, 시네 오쿨리스(Sine oculis) 호메오박스 동족체 6, 시네 오쿨리스 호메오박스 동족체 6(드로소필라), Six9, SIX9를 포함한다. Six6 유전자는 발생 경로에 관련되고, 그의 이상 발현은 T-세포 급성 림프모세포 백혈병 발암에 연관되었다.
서열 번호:25는 염색체 17q21.31 상에 위치하고, NGFR 유전자의 프로모터 영역 및 NGFR 유전자 자체의 일부(p75로도 알려져 있는 신경 성장 인자 수용체, OMIM 162010)를 포함한다. NGFR은 단독으로 또는 다른 수용체와 함께 뉴로트로핀 및 신경돌기 성장 촉진 억제 인자에 결합한다. NGFR은 세포 자멸사, 말초 신경의 말이집 형성 및 축삭 병변 후 중추신경계 재생의 억제에서 일익을 담당하는 것으로 밝혀졌다[도브로스키(Dobrowsky, R. T.), 워너(Werner, M. H.), 카스텔리노(Castellino, A. M.), 카오(Chao, M. V.), 해넌(Hannun, Y. A.), Science 265: 1596-1599, 1994; 코스가야(Cosgaya, J. M.), 챤(Chan, J. R.), 슈터(Shooter, E. M.), Science 298: 1245-1248, 2002; 왕(Wang, K. C.), 킴(Kim, J. A.), 시바산카란(Sivasankaran, R.), 세갈(Segal, R.), 헤(He, Z.), Nature 420: 74-78, 2002]. NGFR 유전자의 메틸화는 이미 결장암의 발생과 연관되어 있었다(PCT/US04/020336).
서열 번호:26은 염색체 17q21.31 상에 위치하고, 유전자 TMEFF2의 프로모터 영역을 포함한다. TMEFF2의 메틸화는 결장암에 관련되었다[Cancer Res. 2000년 9월 1일; 60(17):4907-12].
발명의 개요
본 발명은 환자로부터 단리된 생물학적 샘플에서 셉틴 9(이의 모든 전사 변이형 포함), FOXL2, SARM1, VTN, PRDM6, NR2E1, FAT 및 서열 번호:160 내지 서열 번호:165로 이루어진 군으로부터 선택되는 하나 이상의 유전자 또는 게놈 서열의 발현 수준을 결정함을 포함하는, 상기 환자에서 세포 증식 질환을 검출 및/또는 분류하는 방법을 제공하는데, 이 때 저발현 및/또는 CpG 메틸화는 상기 질환의 존재 또는 부류의 지표이다. 본 발명의 다양한 요지는 효율적이고 독특한 유전자 마커를 제공하는데, 상기 마커의 발현 분석에 의해 세포 증식 질환을 특히 높은 민감도, 특이성 및/또는 예견치로 검출할 수 있다. 뿐만 아니라, 상기 마커는 양성 세포 증식 질환으로부터 종양성 세포 증식 질환(전암 상태 포함)을 구별할 수 있다. 본 발명의 마커는 직장결장 암종 및 간세포 암종의 검출에 특히 적합하다. 직장결장 암종과 관련하여, 본 발명의 시험 방법은 위험한 개체군의 스크리닝에 특히 유용하다. 본 발명의 방법은 개선된 민감도, 특이성 및 적당한 환자 순응성 때문에 종래 기술의 방법(산업 표준 FOBT 포함)에 비해 이점을 갖는다.
본 발명의 방법 및 핵산은 가장 바람직하게는 간암을 검출하거나 또는 간암을 다른 간세포 증식 질환으로부터 구분하는데, 또는 직장결장 암종 또는 전암성 직장결장 세포 증식 질환을 검출하는데 사용된다.
한 실시양태에서, 본 발명은 환자로부터 단리된 생물학적 샘플에서 셉틴 9(이의 모든 전사 변이형 포함), FOXL2, SARM1, VTN, PRDM6, NR2E1, FAT 및 서열 번호:160 내지 서열 번호:165로 이루어진 군으로부터 선택되는 하나 이상의 유전자 또는 게놈 서열의 발현 수준을 결정함을 포함하는, 상기 환자에서 세포 증식 질환을 검출 및/또는 분류하는 방법을 제공하는데, 이 때 저발현 및/또는 CpG 메틸화는 상기 질환의 존재 또는 부류의 지표이다. 한 실시양태에서는, 상기 유전자로부터 전사되는 mRNA의 존재, 부재 또는 수준을 검출함으로써 상기 발현 수준을 결정한다. 추가의 실시양태에서는, 상기 유전자 또는 그의 서열에 의해 코딩되는 폴리펩타이드의 존재, 부재 또는 수준을 검출함으로써 상기 발현 수준을 결정한다.
추가의 바람직한 실시양태에서는, 상기 유전자 내에서의 CpG 메틸화의 존재 또는 부재를 검출함으로써 상기 발현을 결정하며, 이 때 메틸화의 존재는 세포 증식 질환의 존재를 나타낸다. 상기 방법은 i) 환자로부터 수득되는 생물학적 샘플(혈장, 혈청, 전혈, 단리된 혈액 세포, 혈액으로부터 단리된 세포로 이루어진 군으로부터 바람직하게 선택됨)로부터 단리된 게놈 DNA를, 게놈 DNA의 하나 이상의 표적 영역 내에서 메틸화된 CpG 다이뉴클레오타이드와 메틸화되지 않은 CpG 다이뉴클레오타이드를 구분하는 하나 이상의 시약 또는 일련의 시약과 접촉시키는 단계; 및 ii) 적어도 부분적으로 세포 증식 질환을 검출 및/또는 분류하는 단계를 포함하며, 이 때 상기 표적 영역의 뉴클레오타이드 서열은 셉틴 9(그의 모든 전사 변이형 포함), FOXL2, SARM1, VTN, PRDM6, NR2E1, FAT 및 서열 번호:160 내지 서열 번호:165로 이루어진 군으로부터 선택되는 하나 이상의 유전자 또는 게놈 서열의 하나 이상의 CpG 다이뉴클레오타이드 서열을 포함한다. 바람직하게는, 표적 영역은 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번 호:167로 이루어진 군으로부터 선택되는 하나 이상의 서열의 16개 이상의 연속적인 뉴클레오타이드의 서열을 포함하거나 또는 엄격한 조건하에서 상기 서열과 하이브리드 형성한다.
바람직하게는, 상기 검출의 민감도는 약 75% 내지 약 96%, 또는 약 80% 내지 약 90%, 또는 약 80% 내지 약 85%이다. 바람직하게는, 특이성은 약 75% 내지 약 96%, 또는 약 80% 내지 약 90%, 또는 약 80% 내지 약 85%이다.
신체 유체의 분석에 의해, 상업적으로 입수가능하고 또한 관리 기구에 의해 승인된 분석법에 사용하기에 충분히 높은 민감도 및 특이성으로, 암을 검출할 수 있는 방법이 현재 존재하지 않기 때문에, 본 방법은 신규 방법이다. 예를 들면, 직장결장 암종을 검출 및 진단하기 위해 현재 사용되는 방법은 결장경 검사, s상 결장경 검사 및 대변 잠혈 결장암을 포함한다. 이들 방법과 비교하여, 개시되는 본 발명은 결장경보다 훨씬 덜 침습성이고, s상 결장경 검사 및 FOBT보다 더 민감하지는 않더라도 그 만큼은 민감하다. 신체 유체 분석법의 개발은 적어도 직장결장 암종 스크리닝에 있어서 단일 신체 유체에 기초한 시험에 대한 환자 순응성이 FOBT에 대해 현재 권장되는 대변의 3회 분석법보다 더 높을 것으로 예상된다는 점에서 당해 분야에 공지되어 있는 현행 방법에 비해 뚜렷한 기술적 이점을 제공한다.
추가적인 예시로서, 간암을 검출 및 진단하는데 이용되는 현행 방법은 PET 및 MRI 영상 진찰 및 흡출물의 세포학적 스크리닝 또는 생검을 포함한다. 방사선의학 스크리닝 방법은 통상적으로 초기 단계에서 암을 검출하지 못하고 실행하기에 비싸고 시간이 많이 걸린다. 세포학적 스크리닝은 생검(내출혈) 및 흡출(바늘-트랙 시딩(needle-track seeding) 및 출혈, 담즙 복막염 및 기흉)에 수반되는 위험을 제공한다. 따라서, 간암의 초기 단계 검출은 현재 불가능하고, 더욱이 환자 예후 판정이 조기 검출에 의해 크게 개선되기 때문에, 당해 분야에서는 이러한 스크리닝 시험이 요구되고 있다.
특정 실시양태에서, 본 방법은 세포 증식 질환을 검출 및 구분하기 위한 마커로서의, 셉틴 9(그의 모든 전사 변이형 포함), FOXL2, SARM1, VTN, PRDM6, NR2E1, FAT 및 서열 번호:160 내지 서열 번호:165로 이루어진 군으로부터 선택되는 하나 이상의 유전자 또는 게놈 서열의 용도를 포함한다. 본 발명은 종양성 세포 증식 질환(종양전 단계 포함)을 검출하는데 특히 적합하다. 뿐만 아니라, 본 발명의 방법 및 핵산에 의해 악성 세포 증식 질환을 양성 세포 증식 질환으로부터 구별해낼 수 있다. 본 발명의 방법 및 핵산은 직장결장 또는 간 종양 질환 및 종양전 질환의 검출에 특히 효과적이다. 더욱이, 이들은 종양성 세포 증식 직장결장 및 간세포 질환과 양성 세포 증식 직장결장 및 간세포 질환을 구별하는데 유용하다.
유전자의 발현의 임의의 분석법에 의해, mRNA 발현 분석법 또는 단백질 발현 분석법에 의해, 유전자의 상기 사용을 가능케 할 수 있다. 그러나, 본 발명의 가장 바람직한 실시양태에서는, 셉틴 9(그의 모든 전사 변이형 포함), FOXL2, SARM1, VTN, PRDM6, NR2E1, FAT 및 서열 번호:160 내지 서열 번호:165로 이루어진 군으로부터 선택되는 하나 이상의 유전자 또는 게놈 서열, 및 그의 프로모터 또는 조절 요소의 메틸화 현황을 분석함으로써, 직장결장 또는 간세포 증식 질환의 검출, 구 별 및 구분을 가능케 한다.
본 발명은 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167로 이루어진 군으로부터의 하나 이상의 핵산 또는 그의 단편을, 관심 있는 게놈 서열 또는 서열들 내에서 메틸화된 CpG 다이뉴클레오타이드와 메틸화되지 않은 CpG 다이뉴클레오타이드를 구분할 수 있는 시약 또는 일련의 시약과 접촉시킴을 그 특징으로 하는, 세포 증식 질환의 발생에 수반되는 특징에 대해 생물학적 샘플을 분석하는 방법을 제공한다.
본 발명은 종양성 세포 증식 질환(예: 암)의 발생에 관련된 게놈 DNA의 후성학적 매개변수를 확인하는 방법을 제공한다. 이 방법은 상기 질환의 개선된 진단, 치료 및 모니터링에 유용하다.
바람직하게는, 시험 샘플의 공급원은 세포 또는 세포주, 조직학적 슬라이드, 생검체, 파라핀-매립된 조직, 신체 유체, 사정액, 대변, 소변, 혈액 및 이들의 조합으로 이루어진 군으로부터 선택된다. 더욱 바람직하게는, 공급원은 환자로부터 수득된 대변, 혈장, 혈청, 전혈, 단리된 혈액 세포, 혈액으로부터 단리된 세포로 이루어진 군으로부터 선택된다.
구체적으로, 본 발명은 게놈 핵산(들)을 포함하는 생물학적 샘플을 수득하고; 핵산(들) 또는 그의 단편을, 해당 핵산의 하나 이상의 표적 서열 내에서 메틸화된 CpG 다이뉴클레오타이드 서열과 메틸화되지 않은 CpG 다이뉴클레오타이드 서열을 구분하기에 충분한 하나의 시약 또는 복수개의 시약과 접촉시키며; 적어도 부분적으로는 상기 구분에 기초하여, 하나 이상의 표적 CpG 다이뉴클레오타이드 서열 의 메틸화 상태, 또는 평균, 또는 복수개의 표적 CpG 다이뉴클레오타이드 서열의 평균 메틸화 상태를 반영하는 값을 결정함을 포함하는, 초기 전암 단계를 비롯한 종양성 세포 증식 질환(바람직하게는, 직장결장 및/또는 간세포)을 검출하고 종양성 세포 증식 질환과 양성 세포 증식 질환을 구별하는 방법을 제공하며, 이 때 상기 표적 서열은 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167로 이루어진 군으로부터 선택되는 서열의 16개 이상의 연속적인 뉴클레오타이드를 포함하는 서열을 포함하거나 또는 엄격한 조건하에서 상기 서열과 하이브리드 형성하며, 상기 연속적인 뉴클레오타이드는 하나 이상의 CpG 다이뉴클레오타이드 서열을 포함한다.
바람직하게는, 표적 서열 내에서의 메틸화된 CpG 다이뉴클레오타이드 서열과 메틸화되지 않은 CpG 다이뉴클레오타이드 서열의 구분은 서열 번호:10 내지 서열 번호:15, 서열 번호:28 내지 서열 번호:33, 서열 번호:30 내지 서열 번호:31, 서열 번호:42 내지 서열 번호:43, 서열 번호:38 내지 서열 번호:39, 서열 번호:50 내지 서열 번호:51, 서열 번호:168 내지 서열 번호:203으로 이루어진 군으로부터 선택되는 서열 및 표적 서열에 상응하는 이들의 연속적인 영역 내에서 하나 이상의 CpG 다이뉴클레오타이드 서열의 상응하는 전환된 다이뉴클레오타이드 서열 또는 전환되지 않은 다이뉴클레오타이드 서열로의 메틸화 상태에 따른 전환 또는 비-전환을 포함한다.
추가적인 실시양태는 해당 게놈 DNA를 갖는 생물학적 샘플을 수득하고; 게놈 DNA를 추출하고; 게놈 DNA 또는 그의 단편을, 5-위치 메틸화되지 않은 시토신 염기 를 우라실 또는 하이브리드 형성 특성 면에서 시토신과 검출가능하게 상이한 다른 염기로 전환시키는 하나 이상의 시약으로 처리하며; 처리된 게놈 DNA 또는 처리된 그의 단편을 증폭 효소 및 둘 이상의 프라이머와 접촉시키고, 상기 처리된 DNA 또는 그의 단편을 증폭시켜 증폭물을 생성시키거나 증폭시키지 않으며; 상기 증폭물의 존재 또는 부재 또는 상기 증폭물의 특성에 기초하여, 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167로 이루어진 군으로부터 선택되는 서열의 하나 이상, 더욱 바람직하게는 복수개의 CpG 다이뉴클레오타이드의 메틸화 상태 또는 평균 또는 메틸화 수준의 평균을 반영하는 값을 결정함을 포함하는, 종양성 세포 증식 질환(가장 바람직하게는 직장결장 또는 간세포)을 검출하는(또는 이들을 양성 세포 증식 질환으로부터 구분하는) 방법을 제공하며, 이 때 상기 프라이머는 각각의 경우 서열 번호:10 내지 서열 번호:15, 서열 번호:28 내지 서열 번호:33, 서열 번호:30 내지 서열 번호:31, 서열 번호:42 내지 서열 번호:43, 서열 번호:38 내지 서열 번호:39, 서열 번호:50 내지 서열 번호:51, 서열 번호:168 내지 서열 번호:203 및 이들의 보체로 이루어진 군으로부터 선택되는 서열에 대해 상보적이거나 또는 적당히 엄격한 조건 또는 엄격한 조건하에서 상기 서열과 하이브리드 형성하는 뉴클레오타이드 9개 이상의 길이를 갖는 연속적인 서열을 포함한다.
바람직하게는, 결정은 i) 서열 번호:10 내지 서열 번호:15, 서열 번호:28 내지 서열 번호:33, 서열 번호:30 내지 서열 번호:31, 서열 번호:42 내지 서열 번호:43, 서열 번호:38 내지 서열 번호:39, 서열 번호:50 내지 서열 번호:51, 서열 번호:168 내지 서열 번호:203 및 이들의 보체로 이루어진 군으로부터 선택되는 서열에 대해 상보적이거나 또는 적당히 엄격한 조건 또는 엄격한 조건하에서 상기 서열과 하이브리드 형성하는 뉴클레오타이드 9개 이상의 길이를 갖는 연속적인 서열을 포함하는 하나 이상의 핵산 분자를 하이브리드 형성시킴; ii) 서열 번호:10 내지 서열 번호:15, 서열 번호:28 내지 서열 번호:33, 서열 번호:30 내지 서열 번호:31, 서열 번호:42 내지 서열 번호:43, 서열 번호:38 내지 서열 번호:39, 서열 번호:50 내지 서열 번호:51, 서열 번호:168 내지 서열 번호:203 및 이들의 보체로 이루어진 군으로부터 선택되는 서열에 대해 상보적이거나 또는 적당히 엄격한 조건 또는 엄격한 조건하에서 상기 서열과 하이브리드 형성하는 뉴클레오타이드 9개 이상의 길이를 갖는 연속적인 서열을 포함하는, 고상에 결합된 하나 이상의 핵산 분자를 하이브리드 형성시킴; iii) 서열 번호:10 내지 서열 번호:15, 서열 번호:28 내지 서열 번호:33, 서열 번호:30 내지 서열 번호:31, 서열 번호:42 내지 서열 번호:43, 서열 번호:38 내지 서열 번호:39, 서열 번호:50 내지 서열 번호:51, 서열 번호:168 내지 서열 번호:203 및 이들의 보체로 이루어진 군으로부터 선택되는 서열에 대해 상보적이거나 또는 적당히 엄격한 조건 또는 엄격한 조건하에서 상기 서열과 하이브리드 형성하는 뉴클레오타이드 9개 이상의 길이를 갖는 연속적인 서열을 포함하는 하나 이상의 핵산 분자를 하이브리드 형성시키고, 하나 이상의 이렇게 하이브리드 형성된 핵산 분자를 하나 이상의 뉴클레오타이드 염기에 의해 연장시킴; iv) 증폭물의 서열을 결정함으로 이루어진 군으로부터 선택되는 하나 이상의 방법을 이용함을 포함한다.
추가적인 실시양태는 해당 게놈 DNA를 갖는 생물학적 샘플을 수득하고; 게놈 DNA를 추출하고; 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167 또는 엄격한 조건하에서 이들과 하이브리드 형성하는 서열로 이루어진 군으로부터 선택되는 하나 이상의 서열을 포함하는 게놈 DNA 또는 그의 단편을 하나 이상의 메틸화-민감성 제한 효소와 접촉시킴으로써, 게놈 DNA를 소화시켜 소화 단편을 생성시키거나 또는 게놈 DNA를 소화시키지 않으며; 하나 이상의 이러한 단편의 존재 또는 부재 또는 이들 단편의 특성에 기초하여, 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167로 이루어진 군으로부터 선택되는 하나 이상의 게놈 서열의 하나 이상의 CpG 다이뉴클레오타이드 서열의 메틸화 상태, 또는 평균 또는 이들의 복수개의 CpG 다이뉴클레오타이드 서열의 평균 메틸화 상태를 반영하는 값을 결정함을 포함하는, 세포 증식 질환의 분석(즉, 검출 및/또는 분류) 방법을 제공한다. 바람직하게는, 소화되거나 소화되지 않은 게놈 DNA를 상기 결정 전에 증폭시킨다.
추가적인 실시양태는 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167로 이루어진 군으로부터의 서열 내에서 시토신 메틸화 패턴을 분석하기 위한, 신규의 게놈 서열 및 화학적으로 개질된 핵산 서열, 및 올리고뉴클레오타이드 및/또는 PNA-올리고머를 제공한다.
도 1은 셉틴 9 및 Q9HC74 유전자 전사물의 앙상블 인간 게놈 주석을 도시한 다. 서열 번호:2 및 서열 번호:3의 상대적인 위치도 도시된다.
도 2는 3개의 플롯을 제공한다. 왼쪽의 두 플롯은 실시예 2에서 직장결장 암종 및 혈액 샘플의 서열 번호:1의 분석(분석 2) 민감도를 도시한다. 오른쪽의 플롯은 직장결장 암종 검출의 ROC를 제공한다.
도 3은 실시예 4에 따라 다른 암에서 측정된 메틸화 수준을 도시한다.
도 4는 실시예 4에 따라 다른 비-암 질환에서 측정된 메틸화 수준을 도시한다.
도 5 내지 도 29는 실시예 5에 따른 바이설파이트 서열 결정 데이터의 매트릭스를 제공한다. 매트릭스의 각 칼럼은 한 샘플의 반복 실험의 서열 결정 데이터를 나타내고, 각 샘플의 모든 반복 실험은 한 블록에서 함께 군을 이룬다. 매트릭스의 각 횡렬은 단편 내의 단일 CpG 부위를 나타낸다. 증폭물의 CpG 수는 매트릭스의 왼쪽에 도시된다. 각 CpG 위치에서 측정된 메틸화의 양은 밝은 회색(0% 메틸화)으로부터 중간 회색(50% 메틸화), 어두운 회색(100% 메틸화)까지 색상으로 표시된다. 일부 증폭물, 샘플 또는 CpG 위치는 성공적으로 서열이 결정되지 못하였으며, 이들은 백색으로 도시된다.
도 5 내지 도 12는 10% 내지 20% 메틸화를 갖는 것으로 이미 정량된(헤비메틸(HeavyMethyl) 분석법에 의해) 4개의 샘플에서 표 21에 따른 게놈 서열의 바이설파이트 전환된 증폭물의 서열 결정의 개관을 제공한다.
도 13 내지 도 20은 20%보다 높은 메틸화를 갖는 것으로 이미 정량된(헤비메틸(HeavyMethyl™) 분석법에 의해) 2개의 샘플에서 표 21에 따른 게놈 서열의 바이 설파이트 전환된 증폭물의 서열 결정의 개관을 제공한다.
도 21 내지 도 22는 3명의 건강한 개체로부터의 혈액 샘플에서 표 21에 따른 게놈 서열의 바이설파이트 전환된 증폭물의 서열 결정의 개관을 제공한다.
도 23 내지 도 29는 10% 미만(0%보다는 높음)의 메틸화를 갖는 것으로 이미 정량된(헤비메틸 분석법에 의해) 6개의 샘플에서 표 21에 따른 게놈 서열의 바이설파이트 전환된 증폭물의 서열 결정의 개관을 제공한다.
도 30 내지 도 37은 각각 3개의 플롯을 제공한다. 왼쪽의 두 플롯은 실시예 2에서 직장결장 암종 및 혈액 샘플의 표 2에 따른 분석 민감도를 도시한다. 위쪽 플롯은 두 샘플 유형의 2원 분포를 도시하는 반면, 아래쪽 플롯은 다부류 분포를 제공한다. 상기 플롯의 Y-축은 X-축 상에 도시된 정량된 값보다 큰 메틸화 수준을 갖는 분석된 샘플의 비율을 도시한다. 오른쪽의 플롯은 직장결장 암종 검출의 ROC를 제공한다.
정의:
용어 "실측/예측 비"("O/E 비")는 특정 DNA 서열 내의 CpG 다이뉴클레오타이드의 빈도를 말하고, 각 단편의 [CpG 부위의 수/(C 염기의 수×G 염기의 수)]/밴드 길이에 상응한다.
용어 "CpG 섬"은 (1) 0.6보다 큰 "실측/예측 비"에 상응하는 CpG 다이뉴클레오타이드의 빈도를 갖고 (2) 0.5보다 큰 "GC 함량"을 갖는 기준을 충족시키는 게놈 DNA의 연속적인 영역을 말한다. CpG 섬은 전형적으로(항상은 아니지만) 길이가 약 0.2 내지 약 1KB, 또는 약 2Kb이다.
용어 "메틸화 상태" 또는 "메틸화 현황"은 DNA 서열 내에서 하나 또는 복수개의 CpG 다이뉴클레오타이드에서의 5-메틸시토신("5-mCyt")의 존재 또는 부재를 일컫는다. DNA 서열 내에서 하나 이상의 특정 CpG 메틸화 부위(각각 2개의 CpG 다이뉴클레오타이드 서열을 가짐)에서의 메틸화 상태는 "메틸화되지 않음", "완전-메틸화됨" 및 "반-메틸화됨"을 포함한다.
용어 "반-메틸화" 또는 "반메틸화"는 이중 가닥 DNA중 하나의 가닥만이 메틸화된 이중 가닥 DNA의 메틸화 상태를 말한다.
본원에 사용되는 용어 'AUC'는 곡선 아래 면적의 약어이다. 구체적으로 이는 수용자 작동 특징(ROC) 곡선 아래의 면적을 지칭한다. ROC 곡선은 진단 검사의 상이한 가능한 컷(cut) 지점에서 잘못된 양성 비율에 대한 올바른 양성 비율의 플롯이다. 이는 선택된 컷 지점에 따른 민감도와 특이성 사이의 균형을 보여준다(민감도의 임의의 증가는 특이성의 감소를 수반하게 된다). ROC 곡선 아래의 면적(AUC)은 진단 검사의 정확도의 척도이다(면적이 클수록 더욱 우수함, 최적치는 1임, 무작위 검사는 0.5의 면적을 갖는 직사각형으로 도시되는 ROC 곡선을 가짐; 이건(J.P. Egan), Signal Detection Theory and RC Analysis, Academic Press, 뉴욕, 1975 참조).
용어 "과메틸화"는 정상적인 대조용 DNA 샘플 내에서의 상응하는 CpG 다이뉴클레오타이드에서 발견되는 5-mCyt의 양과 비교하여, 시험 DNA 샘플의 DNA 서열 내에서 하나 또는 복수개의 CpG 다이뉴클레오타이드에서의 증가된 5-mCyt 존재에 상응하는 평균 메틸화 상태를 말한다.
용어 "저메틸화"는 정상적인 대조용 DNA 샘플 내에서의 상응하는 CpG 다이뉴클레오타이드에서 발견되는 5-mCyt의 양과 비교하여, 시험 DNA 샘플의 DNA 서열 내에서 하나 또는 복수개의 CpG 다이뉴클레오타이드에서의 감소된 5-mCyt 존재에 상응하는 평균 메틸화 상태를 말한다.
용어 "마이크로어레이"는 광범위하게 "DNA 마이크로어레이" 및 'DNA 칩(들)' 둘 다를 일컬으며, 당해 분야에서 인식되는 바와 같이 당해 분야에서 인식되는 모든 고체 지지체를 포괄하고, 그에 핵산 분자를 부착하거나 그 위에 핵산을 합성하는 모든 방법을 포괄한다.
"유전학적 매개변수"는 조절하는데 추가로 요구되는 유전자 및 서열의 돌연변이 및 다형 현상이다. 돌연변이로서 지칭되는 것은 구체적으로 삽입, 결실, 점 돌연변이, 역전 및 다형 현상, 특히 바람직하게는 SNP(단일 뉴클레오타이드 다형 현상)이다.
"후성학적 매개변수"는 구체적으로 시토신 메틸화이다. 추가의 후성학적 매개변수는 예컨대 기재된 방법을 이용하여 직접 분석될 수 없으나 DNA 메틸화와 상관되어 있는 히스톤의 아세틸화를 포함한다.
용어 "바이설파이트 시약"은 본원에 개시된 바와 같이 메틸화된 CpG 다이뉴클레오타이드 서열과 메틸화되지 않은 CpG 다이뉴클레오타이드 서열을 구분하는데 유용한 바이설파이트, 다이설파이트, 아황산수소 또는 이들의 조합을 포함하는 시약을 지칭한다.
용어 "메틸화 분석법"은 DNA의 서열 내에서 하나 이상의 CpG 다이뉴클레오타이드 서열의 메틸화 상태를 결정하기 위한 임의의 분석법을 말한다.
용어 "MS.AP-PCR"(메틸화-민감성 임의의 프라이머를 사용하는 폴리머라제 연쇄 반응)은 CpG 다이뉴클레오타이드를 함유할 것 같은 영역에 촛점을 맞추어 CG-풍부 프라이머를 사용하여 게놈을 전체적으로 스캔할 수 있으며 곤잘고(Gonzalgo) 등의 문헌[Cancer Research 57:594-599, 1997]에 기재되어 있는 당해 분야에서 인식된 기법을 말한다.
용어 "메틸라이트(MethyLight™)"는 이어즈(Eads) 등의 문헌[Cancer Res . 59:2302-2306, 1999]에 기재되어 있는 당해 분야에서 인식된 형광에 기초한 실시간 PCR 기법을 일컫는다.
본원에서 실행되는 실시양태에서 용어 "헤비메틸(HeavyMethyl™)" 분석법은 증폭 프라이머 사이에서 CpG 위치를 커버하거나 증폭 프라이머에 의해 커버되는 메틸화 특이적 차단 프로브(본원에서는 차단체라고도 함)가 핵산 샘플의 메틸화-특이적인 선택적 증폭을 가능케 하는 분석법을 말한다.
본원에서 실행되는 실시양태에서 용어 "헤비메틸(HeavyMethyl™) 메틸라이트(MethyLight™)" 분석법은 메틸라이트(MethyLight™) 분석법이 증폭 프라이머 사이에서 CpG 위치를 커버하는 메틸화 특이적 차단 프로브와 조합된, 메틸라이트(MethyLight™) 분석법의 변형인 헤비메틸(HeavyMethyl™) 메틸라이트(MethyLight™) 분석법을 지칭한다.
용어 "Ms-SNuPE"(메틸화-민감성 단일 뉴클레오타이드 프라이머 연장)는 곤잘고 및 존스(Jones)의 문헌[Nucleic Acids Res . 25:2529-2531, 1997]에 기재되어 있는 당해 분야에서 인식된 분석법을 일컫는다.
용어 "MSP"(메틸화-특이적 PCR)은 허맨(Herman) 등의 문헌[Proc . Natl . Acad. Sci . USA 93:9821-9826, 1996] 및 미국 특허 제 5,786,146 호에 기재되어 있는 당해 분야에서 인식된 메틸화 분석법을 말한다.
용어 "COBRA"(조합된 바이설파이트 제한 분석법)은 지옹(Xiong) 및 레어드(Laird)의 문헌[Nucleic Acids Res . 25:2532-2534, 1997]에 기재되어 있는 당해 분야에서 인식된 메틸화 분석법을 말한다.
용어 "MCA"(메틸화된 CpG 섬 증폭)는 도요타(Toyota) 등의 문헌[Cancer Res . 59:2307-12, 1999] 및 WO 00/26401A1 호에 기재되어 있는 메틸화 분석법을 지칭한다.
용어 "하이브리드 형성"은 샘플 DNA에서 왓슨-크릭(Watson-Crick) 염기 쌍의 선과 함께 상보적 서열로의 올리고뉴클레오타이드의 결합(이중 가닥 구조를 형성함)으로서 이해된다.
본원에서 정의되는 "엄격한 하이브리드 형성 조건"은 5×SSC/5×덴하르트(Denhardt's) 용액/1.0% SDS에서 68℃에서 하이브리드 형성하고, 실온에서 0.2×SSC/0.1% SDS 중에서 세척함을 포함하거나, 또는 당해 분야에서 인식된 그의 등가물(예를 들어, 60℃에서 2.5×SSC 완충액에서 하이브리드 형성시킨 후, 낮은 완충액 농도에서 37℃에서 수회 세척하며, 안정을 유지하는 조건)을 포함한다. 본원에서 정의된 적당히 엄격한 조건은 3×SSC에서 42℃에서 세척함을 포함하거나 또는 당해 분야에서 인식된 그의 등가물을 포함한다. 염 농도 및 온도 매개변수를 변화시켜 프로브와 표적 핵산 사이의 최적 일치 수준을 달성할 수 있다. 이러한 조건과 관련된 지침은 당해 분야에서, 예컨대 샘브룩(Sambrook) 등의 문헌[1989, Molecular Cloning, A Laboratory Manual, Cold Spring Harbor Press, 뉴욕] 및 오스벨(Ausubel) 등이 편집한 문헌[1995, Current Protocols in Molecular Biology, John Wiley & Sons, 뉴욕, 유닛 2.10]에서 입수가능하다.
용어 "메틸화-특이적 제한 효소" 또는 "메틸화-민감성 제한 효소"는 그의 인식 부위의 메틸화 상태에 따라 핵산을 선택적으로 소화하는 효소를 의미한다. 인식 부위가 메틸화되지 않거나 반메틸화되는 경우에 특이적으로 절단하는 이러한 제한 효소의 경우, 인식 부위가 메틸화되면 절단이 이루어지지 않거나 격감된 효율로 절단이 이루어진다. 인식 부위가 메틸화되는 경우에 특이적으로 절단하는 이러한 제한 효소의 경우, 인식 부위가 메틸화되지 않으면 절단이 이루어지지 않거나 격감된 효율로 절단이 이루어진다. 바람직한 것은 메틸화-특이적 제한 효소이고, 이의 인식 서열은 CG 다이뉴클레오타이드(예컨대, cgcg 또는 cccggg)를 함유한다. 몇몇실시양태에서 또한 바람직한 것은 이 다이뉴클레오타이드의 시토신이 탄소 원자 C5에서 메틸화되는 경우 절단하지 않는 제한 효소이다.
"비-메틸화-특이적 제한 효소" 또는 "비-메틸화-민감성 제한 효소"는 메틸화 상태와 무관하게 거의 동일한 효율로 핵산 서열을 절단하는 제한 효소이다. 이들은 또한 "메틸화-비특이적 제한 효소"로도 불린다.
용어 "유전자"는 그의 모든 전사 변이형(예를 들어, "셉틴 9"는 예를 들어 그의 절단된 전사물 Q9HC74를 포함함), 및 그의 모든 프로모터 및 조절 요소를 포함한다. 뿐만 아니라, 복수개의 SNP가 상기 유전자 내에서 공지되어 있기 때문에, 이 용어는 그의 모든 서열 변이형을 포함한다.
용어 "전암성" 또는 "종양전" 및 그의 등가물은 악성 변형이 진행되는 임의의 세포 증식 질환을 의미한다. 이러한 질병의 예는 직장결장 세포 증식 질환과 관련하여 높은 형성이상 정도를 갖는 세포 증식 질환 및 하기 부류의 선종을 포함한다:
수준 1: 폴립 헤드 내에서 악성 선이 점막내 근육을 통해 점막 하 내로 침투함.
수준 2: 동일한 점막 하 침습이 있으나 헤드와 경상부(stalk)의 접합부에 존재함.
수준 3: 경상부의 침습; 및
수준 4: 결장 벽으로의 연결 부위에 있는 경상부 기저부의 침습(이 수준은 단계 듀크스 A에 상응함).
개괄:
본 발명은 환자로부터 단리된 생물학적 샘플에서 셉틴 9(이의 모든 전사 변이형 포함), FOXL2, SARM1, VTN, PRDM6, NR2E1, FAT 및 서열 번호:160 내지 서열 번호:165로 이루어진 군으로부터 선택되는 하나 이상의 유전자 또는 게놈 서열의 발현 수준을 결정함을 포함하는, 상기 환자에서 세포 증식 질환을 검출 및/또는 분류하는 방법을 제공하는데, 이 때 저발현 및/또는 CpG 메틸화는 상기 질환의 존재 또는 부류의 지표이다. 상기 마커는 질환의 전암 단계 동안의 조기 검출을 비롯한 종양성 세포 증식 질환(암)의 진단, 및 양성 세포 증식 질환으로부터 종양성 세포증식 질환의 구별에 사용될 수 있다. 본 발명은 종양성 세포 증식 질환을 양성 세포 증식 질환으로부터 구분하는 방법을 개시하며, 상기 방법은 저발현 및/또는 CpG 메틸화의 존재가 종양성 세포 증식 질환 또는 종양전 질환의 존재의 지표이고, 그의 부재가 양성 세포 증식 질환의 존재의 지표임을 그 특징으로 한다.
본 발명의 마커는 간 세포 증식 질환을 검출 또는 구분하는데, 또는 직장결장 세포 증식 질환을 검출 또는 구분하는데 특히 효율적이어서, 상기 질환의 조기 검출, 분류 및 치료를 위한 개선된 수단을 제공한다.
셉틴 9(이의 모든 전사 변이형 포함), FOXL2, SARM1, VTN, PRDM6, NR2E1, FAT 및 서열 번호:160 내지 서열 번호:165로 이루어진 군으로부터 선택되는 하나 이상의 유전자 또는 게놈 서열의 메틸화를 분석하는 상기 실시양태에 덧붙여, 본 발명은 암, 특히 간암 및/또는 직장결장암을 검출하기 위한 신규 용도를 갖는, 셉틴 9(이의 모든 전사 변이형 포함), FOXL2, SARM1, VTN, PRDM6, NR2E1, FAT 및 서열 번호:160 내지 서열 번호:165로 이루어진 군으로부터 선택되는 하나 이상의 유전자 또는 게놈 서열을 포함하는 유전자의 추가적인 패널을 제공한다.
첫번째 추가적인 실시양태에서, 본 발명은 셉틴 9(이의 모든 전사 변이형 포함), FOXL2, SARM1, VTN, PRDM6, NR2E1, FAT 및 서열 번호:160 내지 서열 번호:165로 이루어진 군으로부터 선택되는 하나 이상의 유전자 또는 게놈 서열의 CpG 메틸화 현황의 분석에 기초한다. 상기 유전자의 서열이 표 1에 따르는 것이 또한 바람직하다.
DNA 의 바이설파이트 개질은 CpG 메틸화 현황을 사정하는데 이용되는 당해 분야에서 인정된 도구이다. 5-메틸시토신은 원핵생물 세포의 DNA에서 가장 흔한 공유 염기 개질이다. 이는 예를 들어 전사의 조절, 유전자 각인 및 종양 발생에서 일익을 담당한다. 그러므로, 유전자 정보의 성분으로서 5-메틸시토신을 확인하는 것은 상당히 흥미로운 일이다. 그러나, 5-메틸시토신 위치는 서열 결정에 의해 확인될 수 없는데, 5-메틸시토신이 시토신과 동일한 염기 짝짓기 거동을 갖기 때문이다. 뿐만 아니라, 5-메틸시토신에 의해 운송되는 후성학적 정보는 예컨대 PCR 증폭 동안 완전히 상실된다.
5-메틸시토신의 존재에 대해 DNA를 분석하기 위한 가장 흔히 사용되는 방법은 바이설파이트와 시토신의 특이적인 반응(이에 의해, 후속 알칼리 가수분해시, 시토신은 염기 짝짓기 거동에서 티민에 대응하는 우라실로 전환된다)에 기초한다. 그러나, 중요하게는, 5-메틸시토신은 이들 조건하에서 개질되지 않은 채로 유지된다. 결과적으로, 하이브리드 형성 거동에 의해 원래 시토신과 구분될 수 없는 메틸시토신이 이제는 당해 분야에서 인정된 표준 분자 생물학적 기법을 이용하여, 예컨대 증폭 및 하이브리드 형성, 또는 서열 결정에 의해 유일하게 잔류하는 시토신으로서 검출될 수 있는 방식으로 원래의 DNA가 전환된다. 이들 기법은 모두 차별적인 염기 짝짓기 특성에 기초하는데, 이는 이제 충분히 이용될 수 있다.
종래 기술은 민감도의 면에서 분석되어야 하는 DNA를 아가로스 매트릭스에 매립시킴으로써 DNA의 확산 및 재생을 방지하고(바이설파이트는 단일-가닥 DNA와만 반응함) 모든 침전 및 정제 단계를 신속한 투석으로 대체함을 포함하는 방법으로서 정의된다[올렉(Olek A) 등, A modified and improved method for bisulfite based cytosine methylation analysis, Nucleic Acids Res. 24:5064-6, 1996]. 따라서, 개별적인 세포를 메틸화 현황에 대해 분석하여 방법의 효용 및 민감도를 입증할 수 있다. 5-메틸시토신을 검출하기 위한 당해 분야에서 인정된 방법에 대한 개관은 레인(Rein, T.) 등의 문헌[Nucleic Acids Res ., 26:2255, 1998]에 의해 제공된다.
예외를 거의 갖지 않는 바이설파이트 기법[예컨대, 제쉬닉(Zeschnigk M.) 등, Eur J Hum Genet. 5:94-98, 1997]이 현재 연구에 유일하게 이용된다. 모든 경우에, 공지 유전자의 짧고 특이적인 단편을 바이설파이트 처리 후에 증폭시키고, 완전히 서열 결정하고[올렉 및 월터(Walter), Nat Genet . 1997 17:275-6, 1997] 하나 이상의 프라이머 연장 반응시켜[곤잘고 및 존스, Nucleic Acids Res., 25:2529-31, 1997; WO 95/00669 호; 미국 특허 제 6,251,594 호], 개별적인 시토신 위치를 분석하거나, 또는 효소적 소화에 의해 처리한다[지옹 및 레어드, Nucleic Acids Res., 25:2532-4, 1997]. 하이브리드 형성에 의한 검출도 당해 분야에 기재된 바 있다[올렉 등, WO 99/28498 호). 또한, 개별적인 유전자와 관련하여 메틸화 검출을 위한 바이설파이트 기법의 사용이 기재되었다[그리그(Grigg) 및 클라크, Bioessays, 16:431-6, 1994; 제쉬닉 등, Hum Mol Genet., 6:387-95, 1997; 페일(Feil R.) 등, Nucleic Acids Res., 22:695-, 1994; 마틴(Martin V) 등, Gene, 157:261-4, 1995; WO 97/46705 호 및 WO 95/15373 호].
본 발명은 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167로 이루어진 군으로부터 선택되는 하나 이상의 서열 내에서 CpG 다이뉴클레오타이드 서열의 메틸화 현황을 결정하기 위한, 하나 이상의 메틸화 분석법과 함께 바이설파이트 기법의 용도를 제공한다. 게놈 CpG 다이뉴클레오타이드는 메틸화될 수 있거나 메틸화되지 않을 수 있다(또는 각각 상향-메틸화 및 하향-메틸화로도 알려짐). 그러나, 본 발명의 방법은 이질적인 특성의 생물학적 샘플, 예를 들어 혈액 또는 대변의 바탕 내에서 낮은 농도의 종양 세포를 분석하는데 적합하다. 따라서, 이러한 샘플 내에서 CpG 위치의 메틸화 현황을 분석하는 경우, 당해 분야의 숙련자는 메틸화 상태와는 대조적으로 특정 CpG 위치에서의 메틸화의 수준(예컨대, 백분율, 분율, 비, 비율 또는 정도)을 결정하기 위한 정량적인 분석법을 이용할 수 있다. 따라서, 용어 메틸화 현황 또는 메틸화 상태는 또한 CpG 위치에서의 메틸화의 정도를 반영하는 값을 의미하는 것으로 이해되어야 한다. 구체적으로 언급되지 않는 한, 용어 "과메틸화" 또는 "상향 메틸화"는 규정된 컷-오프 점보다 더 높은 메틸화 수준을 의미하며, 이 때 상기 컷-오프는 소정 개체군의 평균 또는 중간 메틸화 수준을 나타내는 값일 수 있거나 또는 바람직하게는 최적화된 컷-오프 수준이다. "컷-오프"는 또한 본원에서 "역치"라고도 한다. 본 발명과 관련하여, 용어 "메틸화", "과메틸화" 또는 "상향 메틸화"는 셉틴 9(이의 모든 전사 변이형 포함), FOXL2, SARM1, VTN, PRDM6, NR2E1, FAT 및 서열 번호:160 내지 서열 번호:165로 이루어진 군으로부터 선택되는 유전자 또는 게놈 서열 내의 또한 이들과 관련된(예컨대, 프로모터 또는 조절 영역) 모든 CpG 위치의 0%(또는 그의 등가물) 메틸화인 컷-오프보다 높은 메틸화 수준을 포함한다.
본 발명에 따라, 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167 내에서 CpG 다이뉴클레오타이드 서열의 메틸화 현황을 결정하는 것은 세포 증식 질환의 진단 및 특징 결정 둘 다에서 유용하다. 메틸화 분석 절차. 다양한 메틸화 분석 절차가 당해 분야에 공지되어 있으며, 본 발명과 함께 사용될 수 있다. 이들 분석법은 DNA 서열 내에서 하나 또는 복수개의 CpG 다이뉴클레오타이드(예컨대, CpG 섬)의 메틸화 상태를 결정할 수 있다. 이러한 분석법은 다른 기법 중에서도 바이설파이트-처리된 DNA의 DNA 서열 결정, PCR(서열-특이적 증폭의 경우), 서던(Southern) 블롯 분석 및 메틸화-민감성 제한 효소의 사용을 포함한다.
예를 들어, DNA 메틸화 패턴 및 바이설파이트 처리에 의한 5-메틸시토틴 분포를 분석하기 위해 게놈 서열 결정을 단순화시켰다[프로머(Frommer) 등, Proc . Natl. Acad . Sci . USA 89:1827-1831, 1992]. 따라서, 바이설파이트-전환된 DNA로부터 증폭된 PCR 생성물의 제한 효소 소화, 예를 들어 사드리(Sadri) 및 혼스비(Hornsby)의 문헌[Nucl . Acids Res. 24:5058-5059, 1996] 또는 COBRA(조합된 바이설파이트 제한 분석)[지옹 및 레어드, Nucleic Acids Res. 25:2532-2534, 1997]를 이용한다.
COBRA . COBRA™ 분석법은 소량의 게놈 DNA중 특정 유전자 위치에서 DNA 메틸화 수준을 결정하는데 유용한 정량적인 메틸화 분석법이다[지옹 및 레어드, Nucleic Acids Res. 25:2532-2534, 1997]. 간단히, 제한 효소 소화를 이용하여 중아황산나트륨-처리된 DNA의 PCR 생성물에서 메틸화-의존성 서열 차이를 드러낸다. 프로머 등의 문헌[Proc . Natl . Acad . Sci . USA 89:1827-1831, 1992]에 기재된 절차에 따른 표준 바이설파이트 처리에 의해 메틸화-의존성 서열 차이를 먼저 게놈 DNA에 도입한다. 이어, 관심 있는 CpG 섬에 특이적인 프라이머를 사용하여 바이설파이트 전환된 DNA를 PCR 증폭시킨 다음, 제한 엔도뉴클레아제 소화, 겔 전기영동 및 특이적인 라벨링된 하이브리드 형성 프로브를 사용한 검출을 수행한다. 원래 DNA 샘플의 메틸화 수준을, 넓은 DNA 메틸화 수준의 스펙트럼을 가로지르는 선형 정량 방식으로 소화된 PCR 생성물 및 소화되지 않은 PCR 생성물의 상대적인 양으로 표시한다. 또한, 이 기법을 현미 해부된 파라핀-매립된 조직 샘플로부터 수득된 DNA에 신뢰성있게 적용할 수 있다.
COBRA™ 분석법에 전형적인 시약(예컨대, 전형적인 COBRA™-계 키트에서 발견되는)은 특이적인 유전자(또는 바이설파이트 처리된 DNA 서열 또는 CpG 섬)에 대한 PCR 프라이머; 제한 효소 및 적절한 완충액; 유전자-하이브리드 형성 올리고뉴클레오타이드; 대조용 하이브리드 형성 올리고뉴클레오타이드; 올리고뉴클레오타이드 프로브에 대한 키나제 라벨링 키트; 및 라벨링된 뉴클레오타이드를 포함할 수 있으나, 이들로 한정되지는 않는다. 또한, 바이설파이트 전환 시약은 DNA 변성 완충액; 설폰화 완충액; DNA 회수 시약 또는 키트(예컨대, 침전, 한외여과, 친화력 칼럼); 탈설폰화 완충액; 및 DNA 회수 성분을 포함할 수 있다.
바람직하게는, "메틸라이트(MethyLight™)"(형광에 기초한 실시간 PCR 기법)[이어즈 등, Cancer Res . 59:2302-2306, 1999), Ms-SNuPE™(메틸화-민감성 단일뉴클레오타이드 프라이머 연장) 반응[곤잘고 및 존스, Nucleic Acids Res. 25:2529-2531, 1997)], 메틸화-특이적 PCR["MSP"; 허맨 등, Proc . Natl . Acad . Sci. USA 93:9821-9826, 1996; 미국 특허 제 5,786,146 호], 및 메틸화된 CpG 섬 증폭["MCA"; 도요타 등, Cancer Res. 59:2307-12, 1999] 같은 분석법을 단독으로 또는 이들 방법중 다른 것과 함께 이용한다.
"헤비메틸(HeavyMethyl™)" 분석 기법은 바이설파이트 처리된 DNA의 메틸화 특이적 증폭에 기초하여 메틸화 차이를 사정하는 정량적인 방법이다. 증폭 프라이머 사이에서 CpG 위치를 커버하거나 증폭 프라이머에 의해 커버되는 메틸화 특이적 차단 프로브(본원에서는 차단체라고도 함)는 핵산 샘플의 메틸화-특이적 선택적인 증폭을 가능케 한다.
본원에서 실행되는 실시양태에서 용어 "헤비메틸(HeavyMethyl™) 메틸라이트(MethyLight™)" 분석법은 메틸라이트(MethyLight™) 분석법이 증폭 프라이머 사이의 CpG 위치를 커버하는 메틸화 특이적인 차단 프로브와 조합된, 메틸라이트(MethyLight™) 분석법의 변형인 헤비메틸(HeavyMethyl™) 메틸라이트(MethyLight™) 분석법을 말한다. 헤비메틸(HeavyMethyl™) 분석법을 또한 메틸화 특이적인 증폭 프라이머와 함께 사용할 수도 있다.
헤비메틸(HeavyMethyl™) 분석에 전형적인 시약(예컨대, 전형적인 메틸라이트-계 키트에서 발견되는)은 특정 유전자(또는 바이설파이트 처리된 DNA 서열 또는 CpG 섬); 차단 올리고뉴클레오타이드; 최적화된 PCR 완충액 및 데옥시뉴클레오타이드; 및 Taq 폴리머라제를 포함할 수 있으나 이들로 한정되지는 않는다.
MSP . MSP(메틸화-특이적 PCR)는 메틸화-민감성 제한 효소의 사용과 무관하게 CpG 섬 내에서 CpG 부위의 본질적인 임의의 군의 메틸화 현황을 사정할 수 있다[허맨 등, Proc . Natl . Acad . Sci . USA 93:9821-9826, 1996; 미국 특허 제 5,786,146 호]. 간단히, DNA를 중아황산나트륨에 의해 개질시켜 모든 메틸화되지 않은 시토신(메틸화된 시토신은 아님)을 우라실로 전환시킨 후, 메틸화되지 않은 DNA에 비해 메틸화된 DNA에 특이적인 프라이머로 증폭시킨다. MSP는 소량의 DNA만을 필요로 하고, 소정 CpG 섬 위치의 0.1% 메틸화된 대립 유전자에 민감하며, 파라핀-매립된 샘플로부터 추출된 DNA 상에서 수행될 수 있다. MSP 분석에 전형적인 시약(예를 들어 전형적인 MSP-계 키트에서 발견되는)은 특정 유전자(또는 바이설파이트 처리된 DNA 서열 또는 CpG 섬)에 대한 메틸화된 PCR 프라미어 및 메틸화되지 않은 PCR 프라이머, 최적화된 PCR 완충액 및 데옥시뉴클레오타이드, 및 특이적인 프로브를 포함할 수 있으나, 이들로 제한되는 것은 아니다.
메틸라이트 ( MethyLight ™). 메틸라이트(MethyLight™) 분석법은 PCR 단계 후에 추가적인 조작을 필요로 하지 않는 형광에 기초한 실시간 PCR[택맨(TaqMan; 등록상표)] 기법을 이용하는 고-처리량의 정량적인 메틸화 분석법이다. 간락하게, 메틸라이트(MethyLight™) 과정은 중아황산나트륨 반응에서 표준 절차(바이설파이트 과정은 메틸화되지 않은 시토신 잔기를 우라실로 전환시킴)에 따라 메틸화-의존성 서열 차이의 혼합된 풀(pool)로 전환되는 게놈 DNA의 혼합된 샘플로 시작된다. 이어, 형광에 기초한 PCR을 "치우친"(공지 CpG 다이뉴클레오타이드와 겹치는 PCR 프라이머를 가짐) 반응으로 수행한다. 증폭 과정의 수준에서 또한 형광 검출 과정의 수준에서 서열 식별이 이루어질 수 있다.
게놈 DNA 샘플의 메틸화 패턴에 대한 정량적인 시험으로서 메틸라이트(MethyLight™) 분석법을 이용할 수 있으며, 이 때 프로브 하이브리드 형성 수준에서 서열 식별이 이루어진다. 이 정량적인 분석법에서, PCR 반응은 특정한 예측된 메틸화 부위와 겹치는 형광 프로브의 존재하에 메틸화 특이적 증폭을 제공한다. 프라이머도 프로브도 임의의 CpG 다이뉴클레오타이드와 겹치지 않는 반응에 의해 투입 DNA의 양이 치우치지 않게 제어된다. 다르게는, 공지의 메틸화 부위를 "커버"하지 않는 대조용 올리고뉴클레오타이드[헤비메틸(HeavyMethyl™) 및 MSP 기법의 형광에 기초한 형태] 또는 가능한 메틸화 부위를 커버하는 올리고뉴클레오타이드로 치우친 PCR 풀을 조사함으로써 게놈 메틸화에 대한 정량적인 시험을 달성한다.
임의의 적합한 프로브, 예컨대 "택맨(TaqMan; 등록상표)", 라이트사이클러(Lightcycler; 등록상표) 등으로 메틸라이트(MethyLight™) 과정을 이용할 수 있다. 예를 들어, 이중-가닥 게놈 DNA를 중아황산나트륨으로 처리하고, 택맨(TaqMan; 등록상표) 프로브를 사용하는(예를 들어, MSP 프라이머 및/또는 헤비메틸 차단체 올리고뉴클레오타이드 및 택맨(TaqMan; 등록상표) 프로브를 사용하는) 두 세트의 PCR 반응중 하나를 수행한다. 택맨(TaqMan; 등록상표) 프로브는 형광 "리포터" 및 "켄처(quencher)" 분자로 이중-라벨링되고, 비교적 높은 GC 함량 영역에 특이적이어서 PCR 사이클에서 전진 또는 후진 프라이머보다 약 10℃ 더 높은 온도에서 용융되도록 디자인된다. 이로 인해, 택맨(TaqMan; 등록상표) 프로브는 PCR 어닐링/연장 단계 동안 완전히 하이브리드 형성된 상태로 유지될 수 있다. Taq 폴리머라제가 PCR 동안 신규 가닥을 효소적으로 합성하기 때문에, 이는 결국 어닐링된 택맨(TaqMan; 등록상표) 프로브에 도달하게 된다. 이어, Taq 폴리머라제 5' 내지 3' 엔도뉴클레아제 활성은 택맨(TaqMan; 등록상표) 프로브를 소화시켜, 실시간 형광 검출 시스템을 이용하여 이제 소멸되지 않은 신호를 정량적으로 검출하기 위한 형광 리포터 분자를 방출시킴으로써 상기 프로브를 제거하게 된다.
메틸라이트(MethyLight™) 분석법에 전형적인 시약(예컨대, 전형적인 메틸라이트(MethyLight™)-계 키트에서 발견되는)은 특정 유전자(또는 바이설파이트 처리된 DNA 서열 또는 CpG 섬)의 PCR 프라이머; 택맨(TaqMan; 등록상표) 또는 라이트사이클러(Lightcycler; 등록상표) 프로브; 최적화된 PCR 완충액 및 데옥시뉴클레오타이드; 및 Taq 폴리머라제를 포함할 수 있으나, 이들로 국한되지는 않는다.
QM™(정량적 메틸화) 분석법은 프로브 하이브리드 형성 수준에서 서열 식별이 이루어지는, 게놈 DNA 샘플에서의 메틸화 패턴에 대한 다른 정량적인 시험이다. 이 정량적인 시험에서, PCR 반응은 특정한 추정된 메틸화 부위와 겹치는 형광 프로브의 존재하에서의 치우치지 않은 증폭을 제공한다. 프라이머도 프로브도 임의의 CpG 다이뉴클레오타이드와 겹치지 않는 반응에 의해 투입 DNA의 양을 치우치지 않게 제어한다. 다르게는, 공지의 메틸화 부위를 "커버하지" 않는 대조용 올리고뉴클레오타이드(헤비메틸(HeavyMethyl™) 및 MSP 기법의 형광에 기초한 형태) 또는 가능한 메틸화 부위를 커버하는 올리고뉴클레오타이드를 사용하여 치우친 PCR 풀을 조사함으로써 게놈 메틸화에 대한 정량적인 시험을 달성한다.
증폭 과정에서 임의의 적합한 프로브, 예컨대 "택맨(TaqMan; 등록상표)", 라이트사이클러(Lightcycler; 등록상표) 등으로 QM™ 과정을 이용할 수 있다. 예를 들어, 이중-가닥 게놈 DNA를 중아황산나트륨으로 처리하고, 치우치지 않은 프라이머 및 택맨(TaqMan; 등록상표) 프로브를 거치게 한다. 택맨(TaqMan; 등록상표) 프로브는 형광 "리포터" 및 "켄처" 분자로 이중-라벨링되고, 비교적 높은 GC 함량 영역에 특이적이어서 PCR 사이클에서 전진 또는 후진 프라이머보다 약 10℃ 더 높은 온도에서 용융되도록 디자인된다. 이에 의해 택맨(TaqMan; 등록상표) 프로브는 PCR 어닐링/연장 단계 동안 완전히 하이브리드 형성된 채로 유지된다. Taq 폴리머라제가 PCR 동안 신규 가닥을 효소적으로 합성하기 때문에, 이는 결국 어닐링된 택맨(TaqMan; 등록상표) 프로브에 도달하게 된다. 이어, Taq 폴리머라제 5' 내지 3' 엔도뉴클레아제 활성은 택맨(TaqMan; 등록상표) 프로브를 소화시켜, 실시간 형광 검출 시스템을 이용하여 이제 소멸되지 않은 신호를 정량적으로 검출하기 위한 형광 리포터 분자를 방출시킴으로써 상기 프로브를 제거하게 된다. QM™ 분석법에 전형적인 시약(예컨대, 전형적인 QM™-계 키트에서 발견되는)은 특정 유전자(또는 바이설파이트 처리된 DNA 서열 또는 CpG 섬)의 PCR 프라이머; 택맨(TaqMan; 등록상표) 또는 라이트사이클러(Lightcycler; 등록상표) 프로브; 최적화된 PCR 완충액 및 데옥시뉴클레오타이드; 및 Taq 폴리머라제를 포함할 수 있으나, 이들로 국한되지는 않는다.
Ms - SNuPE. Ms-SNuPE™ 기법은 DNA의 바이설파이트 처리 후 단일-뉴클레오타이드 프라이머 연장에 기초하여 특이적인 CpG 부위에서 메틸화 차이를 사정하는 정량적인 방법이다[곤잘고 및 존스, Nucleic Acids Res . 25:2529-2531, 1997]. 간단하게, 게놈 DNA를 중아황산나트륨과 반응시켜 5-메틸시토신을 변화시키지 않은 채로 두면서 메틸화되지 않은 시토신을 우라실로 전환시킨다. 이어, 바이설파이트-전환된 DNA에 특이적인 PCR 프라이머를 사용하여 목적하는 표적 서열을 증폭시키고, 생성되는 생성물을 단리한 후 관심 있는 CpG 부위(들)에서 메틸화 분석에 대한 주형으로 사용한다. 소량의 DNA를 분석할 수 있고(예를 들어, 현미 해부된 병리학적 구획), 이는 CpG 부위에서 메틸화 현황을 결정하기 위한 제한 효소의 사용을 피한다.
Ms-SNuPE™ 분석법에 전형적인 시약(예컨대, 전형적인 Ms-SNuPE™-계 키트에서 발견되는)은 특정 유전자(또는 바이설파이트 처리된 DNA 서열 또는 CpG 섬)의 PCR 프라이머; 최적화된 PCR 완충액 및 데옥시뉴클레오타이드; 겔 추출 키트; 양성 대조용 프라이머; 특정 유전자에 대한 Ms-SNuPE™ 프라이머; 반응 완충액(Ms-SNuPE 반응용); 및 라벨링된 뉴클레오타이드를 포함할 수 있으나, 이들로 국한되지는 않는다. 또한, 바이설파이트 전환 시약은 DNA 변성 완충액; 설폰화 완충액; DNA 회수 시약 또는 키트(예컨대, 침전, 한외여과, 친화력 칼럼); 탈설폰화 완충액; 및 DNA 회수 성분을 포함할 수 있다.
서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167에 따른 게놈 서열, 및 서열 번호:10 내지 서열 번호:15, 서열 번호:28 내지 서열 번호:33, 서열 번호:30 내지 서열 번호:31, 서열 번호:42 내지 서열 번호:43, 서열 번호:38 내지 서열 번호:39, 서열 번호:50 내지 서열 번호:51, 서열 번호:168 내지 서열 번호:203에 따른 이들의 비-천연 발생 처리된 변이형은 세포 증식 질환, 구체적으로 직장결장 세포 증식 질환 및/또는 간 세포 증식 질환의 조기 검출, 분류 및/또는 치료에 신규의 효용을 갖는 것으로 결정되었다.
한 실시양태에서, 본 발명의 방법은 i) 환자로부터 수득되는 게놈 DNA(바람직하게는 신체 유체로부터 단리됨)를, 셉틴 9(그의 모든 전사 변이형 포함), FOXL2, SARM1, VTN, PRDM6, NR2E1, FAT 및 서열 번호:160 내지 서열 번호:165로 이루어진 군으로부터 선택되는 하나 이상의 유전자 또는 게놈 서열(이들의 프로모터 및 조절 영역 포함) 내에서 메틸화된 CpG 다이뉴클레오타이드와 메틸화되지 않은 CpG 다이뉴클레오타이드를 구분하는 하나 이상의 시약 또는 일련의 시약과 접촉시키는 단계; 및 ii) 80% 이상의 민감도 및 80% 이상의 특이성으로, 제공되는 결장 또는 간세포 증식 질환을 검출하거나 또는 상기 질환을 검출 및 구분하는 단계를 포함한다.
바람직하게는, 민감도는 약 75% 내지 약 96%, 또는 약 80% 내지 약 90%, 또는 약 80% 내지 약 85%이다. 바람직하게는, 특이성은 약 75% 내지 약 96%, 또는 약 80% 내지 약 90%, 또는 약 80% 내지 약 85%이다.
시판중인 키트의 사용을 비롯한 당해 분야에서 표준인 임의의 수단에 의해 게놈 DNA를 단리할 수 있다. 간단하게, 관심 있는 DNA가 세포막에 의해 캡슐화되는 경우, 생물학적 샘플을 효소적, 화학적 또는 기계적 수단에 의해 부수고 용해시켜야 한다. 이어, 프로테이나제 K를 사용하여 소화시킴으로써 DNA 용액으로부터 단백질 및 다른 오염물을 제거할 수 있다. 이어, 게놈 DNA를 용액으로부터 회수한다. 염석, 유기 추출 또는 DNA의 고상 지지체로의 결합을 비롯한 다양한 방법에 의해 이를 수행할 수 있다. 시간, 비용 및 필요한 DNA 양을 비롯한 수개의 인자에 의해 방법의 선택이 영향을 받는다. 신생물 또는 종양전 물질을 포함하는 모든 임상적인 샘플 유형이 본 방법에 사용하기 적합하며, 세포주, 조직학적 슬라이드, 생검체, 파라핀-매립된 조직, 신체 유체, 대변, 결장 유출물, 소변, 혈장, 혈청, 전혈, 단리된 혈액 세포, 혈액으로부터 단리된 세포 및 이들의 조합이 바람직하다. 신체 유체는 DNA의 바람직한 공급원이고; 특히 바람직한 것은 혈장, 혈청, 전혈, 단리된 혈액 세포 및 혈액으로부터 단리된 세포이다.
이어, 게놈 DNA의 하나 이상의 표적 영역 내에서 메틸화된 CpG 다이뉴클레오타이드와 메틸화되지 않은 CpG 다이뉴클레오타이드를 구분하는 하나 이상의 시약 또는 일련의 시약으로 게놈 DNA 샘플을 처리하며, 이 때 표적 영역은 각각 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167로 이루어진 군으로부터 선택되는 하나 이상의 서열의 16개 이상의 연속적인 뉴클레오타이드의 서열을 포함하거나 엄격한 조건하에서 상기 서열과 하이브리드 형성시키고, 상기 연속적인 뉴클레오타이드는 하나 이상의 CpG 다이뉴클레오타이드 서열을 포함한다.
상기 시약이 5'-위치에서 메틸화되지 않은 시토신 염기를 우라실, 티민 또는 하이브리드 형성 거동 면에서 시토신과 상이한 다른 염기로 전환시키는 것이 특히 바람직하다. 그러나, 다른 실시양태에서, 상기 시약은 메틸화 민감성 제한 효소일 수 있다.
5'-위치에서 메틸화되지 않은 시토신 염기를 우라실, 티민 또는 하이브리드 형성 거동 면에서 시토신과 상이한 다른 염기로 전환시키는 방식으로 게놈 DNA 샘플을 처리하는 경우, 바이설파이트(아황산수소, 다이설파이트)를 사용하여, 이어 알칼리 가수분해를 이용하여 이 처리를 수행한다. 이러한 처리는 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167을, 상기 CpG 다이뉴클레오타이드가 메틸화되는 경우 (각각) 서열 번호:10 내지 서열 번호:15, 서열 번호:30 내지 서열 번호:31, 서열 번호:38 내지 서열 번호:39, 서열 번호:168 내지 서열 번호:185로, 또는 상기 CpG 다이뉴클레오타이드가 메틸화되지 않는 경우 서열 번호:28 내지 서열 번호:33, 서열 번호:42 내지 서열 번호:43, 서열 번호:50 내지 서열 번호:51, 서열 번호:186 내지 서열 번호:203으로 전환시킨다.
이어, 표적 유전자 서열(처리되기 전에 셉틴 9(그의 모든 전사 변이형 포함), FOXL2, SARM1, VTN, PRDM6, NR2E1, FAT 및 서열 번호:160 내지 서열 번호:165로 이루어진 군으로부터 선택되는 하나 이상의 유전자 또는 게놈 서열)의 메틸화 상태를 결정하기 위하여, 처리된 DNA를 분석한다. 표적 영역이 셉틴 9(그의 모든 전사 변이형 포함), FOXL2, SARM1, VTN, PRDM6, NR2E1, FAT 및 서열 번호:160 내지 서열 번호:165로 이루어진 군으로부터 선택되는 하나 이상의 유전자 또는 게놈 서열의 16개 이상의 연속적인 뉴클레오타이드를 포함하거나 또는 엄격한 조건하에서 이들 뉴클레오타이드와 하이브리드 형성시키는 것이 특히 바람직하다. 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167에 따른 상기 유전자의 서열을 분석하는 것이 바람직하다. 분석 방법은 본원에 나열된 것을 비롯하여 당해 분야에 공지되어 있는 것으로부터 선택될 수 있다. 특히 바람직한 것은 메틸라이트(MethyLight™), MSP 및 본원에 기재된 차단 올리고뉴클레오타이드의 사용[헤비메틸(HeavyMethyl™)]이다. 이러한 분석법에 사용되는 임의의 올리고뉴클레오타이드(프라이머, 차단 올리고뉴클레오타이드 및 검출 프로브 포함)가 서열 번호:10 내지 서열 번호:15, 서열 번호:28 내지 서열 번호:33, 서열 번호:30 내지 서열 번호:31, 서열 번호:42 내지 서열 번호:43, 서열 번호:38 내지 서열 번호:39, 서열 번호:50 내지 서열 번호:51, 서열 번호:168 내지 서열 번호:203 및 이들에 상보적인 서열중 하나 이상의 염기 서열의 염기쌍 16개 이상의 길이의 구획과 역 상보적이거나, 동일하거나 또는 엄격하거나 매우 엄격한 조건하에서 상기 구획과 하이브리드 형성될 수 있어야 하는 것이 추가로 바람직하다.
셉틴 9(그의 모든 전사 변이형 포함), FOXL2, SARM1, VTN, PRDM6, NR2E1, FAT 및 서열 번호:160 내지 서열 번호:165로 이루어진 군으로부터 선택되는 유전자 또는 게놈 서열(그의 프로모터 및/또는 조절 영역 포함)의 이상 메틸화, 더욱 구체적으로 과메틸화는 종양성 세포 증식 질환의 존재와 관련이 있으며, 직장결장 암종 및 간세포 암종에서 특히 우세하다. 따라서, 생물학적 샘플이 임의의 정도 내의 메틸화를 보이면, 상기 샘플은 종양성인 것으로 결정되어야 한다.
셉틴 9(그의 모든 전사 변이형 포함), FOXL2, SARM1, VTN, PRDM6, NR2E1, FAT 및 서열 번호:160 내지 서열 번호:165로 이루어진 군으로부터 선택되는 하나의 유전자 또는 게놈 서열을 분석하면, 최초로 80% 이상의 민감도 및 80% 이상의 특이성으로 결장 또는 간 세포 증식 질환의 검출 또는 검출 및 구분을 가능케 한다. 민감도는 (검출된 신생물 형성/모든 신생물 형성), 예컨대 (검출된 결장 신생물 형성/모든 결장 신생물 형성)으로서 계산되고, 특이성은 (검출되지 않은 음성/전체 음성)으로서 계산된다.
바람직하게는, 민감도는 약 75% 내지 약 96%, 또는 약 80% 내지 약 90%, 또는 약 80% 내지 약 85%이다. 바람직하게는, 특이성은 약 75% 내지 약 96%, 또는 약 80% 내지 약 90%, 또는 약 80% 내지 약 85%이다.
결장 신생물은 본원에서 1cm보다 큰 모든 결장 악성 종양 및 선종, 또는 이들의 부분집합으로서 정의된다. 음성은 건강한 개체로서 정의될 수 있다.
한 실시양태에서, 본 방법은 세포 증식 질환(구체적으로는 종양성 결장 또는 간 질환)의 구별, 검출 및 구분을 위한 마커로서의, 셉틴 9(그의 모든 전사 변이형 포함), FOXL2, SARM1, VTN, PRDM6, NR2E1, FAT 및 서열 번호:160 내지 서열 번호:165로 이루어진 군으로부터 선택되는 하나 이상의 유전자 또는 게놈 서열(또는 그의 프로모터 및/또는 조절 영역)의 용도를 개시한다.
그로부터 전사된 RNA 또는 상기 RNA로부터 번역된 폴리펩타이드 또는 단백질의 발현의 임의의 분석에 의해, 바람직하게는 mRNA 발현 분석 또는 폴리펩타이드 발현 분석에 의해 상기 방법이 가능해질 수 있다. 따라서, 본 발명은 또한 환자에서 셉틴 9(그의 모든 전사 변이형 포함), FOXL2, SARM1, VTN, PRDM6, NR2E1, FAT 및 서열 번호:160 내지 서열 번호:165로 이루어진 군으로부터 선택되는 하나 이상의 유전자 또는 게놈 서열의 발현을 검출하고, 그로부터 상기 환자에서의 암의 존재 또는 부재를 결정하기 위한 정량적 및 정성적 진단 분석법 및 방법도 제공한다.
셉틴 9(그의 모든 전사 변이형 포함), FOXL2, SARM1, VTN, PRDM6, NR2E1, FAT 및 서열 번호:160 내지 서열 번호:165로 이루어진 군으로부터 선택되는 유전자 또는 게놈 서열로부터 전사된 mRNA의 이상 발현은 환자에서의 암의 존재와 관련이 있다. 본 발명에 따라, 저발현(및/또는 메틸화의 존재)은 암의 존재와 관련이 있고, 반대로 과발현(및/또는 메틸화의 부재)은 암의 부재와 관련이 있다. 유전자 셉틴 9의 서열 번호:16 내지 서열 번호:19에 개시되는 하나 이상의 전사 변이형의 발현을 결정하는 것이 특히 바람직하다.
유전자 또는 게놈 서열을 코딩하는 mRNA의 존재를 검출하기 위해서, 환자로부터 샘플을 수득한다. 샘플은 종양의 세포 물질을 포함하는 임의의 적합한 샘플일 수 있다. 적합한 샘플 유형은 세포주, 조직학적 슬라이드, 생검체, 파라핀-매립된 조직, 생체 유체, 대변, 결장 유출물, 소변, 혈장, 혈청, 전혈, 단리된 혈액 세포, 혈액으로부터 단리된 세포 및 이들의 모든 가능한 조합을 포함한다. 상기 샘플 유형이 대변 또는 결장 유출물, 소변, 혈장, 혈청, 전혈, 단리된 혈액 세포, 혈액으로부터 단리된 세포로 이루어진 군으로부터 선택되는 신체 유체인 것이 바람직하다.
샘플을 처리하여 그에 함유된 RNA를 추출할 수 있다. 이어, 샘플로부터 수득된 핵산을 분석한다. 유전자 발현의 절대 및 상대 수준을 결정하기 위한 다수의 기법이 당해 분야에 공지되어 있고, 본 발명에 사용하기 적합한 통상적으로 사용되는 기법은 동일 반응계내 하이브리드 형성(예: FISH), 노던 분석, RNase 보호 분석(RPA), 마이크로어레이 및 PCR에 기초한 기법(예: 정량적인 PCR 및 분별 디스플레이 PCR) 또는 임의의 다른 핵산 검출 방법을 포함한다.
역전사/중합 연쇄 반응 기법(RT-PCR)의 이용이 특히 바람직하다. RT-PCR의 방법은 당해 분야에 널리 공지되어 있다(예컨대, 왓슨 및 플레밍의 상기 문헌 참조).
다음과 같이 RT-PCR 방법을 수행할 수 있다. 예를 들어 표준 구아니듐 아이소티오사이아네이트 방법에 의해 전체 세포 RNA를 단리하고, 전체 RNA를 역전사시킨다. 역전사 방법은 역전사 효소 및 3' 말단 올리고뉴클레오타이드 dT 프라이머 및/또는 무작위적인 6량체 프라이머를 사용하여 RNA의 주형 상에서 DNA를 합성함을 포함한다. 이렇게 생성된 cDNA를 PCR에 의해 증폭시킨다[벨야브스키(Belyavsky) 등, Nucl Acid Res 17:2919-2932, 1989; 크럭(Krug) 및 버거(Berger), Methods in Enzymology, Academic Press, 뉴욕, Vol. 152, pp. 316-325, 1987, 본원에 참고로 인용됨]. 하이브리드 형성 프로브(예컨대, 택맨, 라이트사이클러, 몰레큘라 비콘즈 앤드 스콜피온) 또는 SYBR 그린에 의해 PCR 생성물을 검출하는 RT-PCR의 실시간 변형도 바람직하다. 이어, 표준 곡선을 참조함으로써 또는 Ct 값을 보정 기준의 Ct 값과 비교함으로써, 프로브 또는 SYBR 그린으로부터 검출된 신호를 정량한다. 종종 관리(housekeeping) 유전자의 분석을 이용하여 결과를 정규화시킨다.
노던 블롯 분석에서는, 변성 아가로즈 겔 상에서 전체 또는 폴리(A)+mRNA를 실행시키고, 건조된 겔 자체 내에서 또는 막 상에서 라벨링된 프로브와 하이브리드 형성시킴으로써 검출한다. 생성되는 신호는 RNA 개체군중 표적 RNA의 양에 비례한다.
둘 이상의 세포 개체군 또는 조직으로부터의 신호를 비교하면, 유전자 발현 수준의 상대적인 차이가 드러난다. 공지량의 표적 RNA에 상응하는 시험관내 전사물을 사용하여 생성시킨 표준 곡선과 신호를 비교함으로써 절대 정량화를 수행할 수 있다. 관리 유전자, 즉 조건에 관계없이 그의 발현 수준이 비교적 일정하게 유지될 것으로 예상되는 유전자의 분석을 종종 이용하여 결과를 정규화시킴으로써, RNA의 막으로의 동일하지 않은 전달 또는 RNA의 겔 상으로의 동일하지 않은 로딩에 의해 야기되는 임의의 명백한 차이를 없앤다.
노던 분석의 제 1 단계는 관심 있는 세포 또는 조직으로부터 순수하고 완전한 RNA를 단리하는 것이다. 노던 블롯이 크기에 의해 RNA를 구분하기 때문에, 샘플 강도는 신호가 단일 밴드로 편재되는 정도에 영향을 끼친다. 부분 열화된 RNA 샘플은 수개의 밴드에 걸쳐 번지거나 분포하는 신호를 생성시켜서, 민감도를 전반적으로 상실시키고 데이터를 잘못 번역할 수 있게 한다. 노던 블롯 분석에서는, DNA, RNA 및 올리고뉴클레오타이드 프로브를 사용할 수 있고, 이들 프로브를 바람직하게는 라벨링한다(예컨대, 방사성 라벨, 질량 라벨 또는 형광 라벨). 프로브가 아니라 표적 RNA의 크기가 검출되는 밴드의 크기를 결정하게 되어, 가변적인 길이의 프로브를 생성시키는 무작위적인 프라이머를 사용한 라벨링 같은 방법이 프로브 합성에 적합하다. 프로브의 특이적인 활성이 민감도 수준을 결정하게 되어, 높은 특이적 활성을 갖는 프로브를 사용하는 것이 바람직하다.
RNase 보호 분석법에서는, RNA 표적 및 한정된 길이의 RNA 프로브를 용액 중에서 하이브리드 형성시킨다. 하이브리드 형성 후, 단일-가닥 핵산에 특이적인 RNase로 RNA를 소화시켜 임의의 하이브리드 형성되지 않은 단일-가닥 표적 RNA 및 프로브를 제거한다. RNase를 불활성화시키고, 예컨대 변성 폴리아크릴아마이드 겔 전기 영동에 의해 RNA를 분리한다. 완전한 RNA 프로브의 양은 RNA 개체군중 표적 RNA의 양에 비례한다. RPA를 유전자 발현의 상대 및 절대 정량에, 또한 인트론/엑손 경계 및 전사 개시 부위 같은 RNA 구조를 맵핑하는데 사용할 수 있다. RNase 보호 분석법은 일반적으로 더 낮은 검출 한계를 갖기 때문에 노던 블롯 분석법보다 바람직하다.
한정된 종결점을 갖는 DNA 주형의 시험관내 전사에 의해 RPA에 사용되는 안티센스 RNA 프로브를 생성시키고, 이들은 전형적으로 50 내지 600개의 뉴클레오타이드이다. 표적 RNA에 일치하지 않는 추가적인 서열을 포함하는 RNA 프로브의 사용에 의해, 보호된 단편을 전체-길이 프로브로부터 구분해낼 수 있다. 단일-가닥 RNA 프로브의 생성의 용이성 및 RNase를 사용한 RNA:RNX 이중 소화의 재현성 및 신뢰성 때문에 DNA 프로브 대신 RNA 프로브를 전형적으로 사용하며(오스벨 등, 2003), 특히 바람직한 것은 높은 특이적 활성을 갖는 프로브이다.
특히 바람직한 것은 마이크로어레이의 사용이다. 마이크로어레이 분석 과정은 2개의 주요 부분으로 나뉠 수 있다. 첫번째는 공지 유전자 서열을 유리 슬라이드 또는 다른 고체 지지체 상에 부동화시킨 다음 형광 라벨링된 cDNA(호출되어야 하는 서열 포함)와 유리 슬라이드(또는 다른 고상)에 부동화된 공지 유전자를 하이브리드 형성시킨다. 하이브리드 형성 후, 형광 마이크로어레이 스캐너를 사용하여 어레이를 스캔한다. 상이한 유전자의 상대적인 형광 강도를 분석하여 유전자 발현에서의 차이의 척도를 제공한다.
미리 합성된 올리고뉴클레오타이드를 제조된 유리 슬라이드 또는 다른 고체 표면 상으로 부동화시킴으로써 DNA 어레이를 생성시킬 수 있다. 이 경우, 표준 올리고뉴클레오타이드 합성 및 정제 방법을 이용하여 대표적인 유전자 서열을 제작 및 제조한다. 이들 합성된 유전자 서열은 관심 있는 유전자(이 경우에는, 셉틴 9(그의 모든 전사 변이형 포함), FOXL2, SARM1, VTN, PRDM6, NR2E1, FAT 및 서열 번호:160 내지 서열 번호:165로 이루어진 군으로부터 선택되는 유전자 또는 게놈 서열)의 RNA 전사물(들)에 상보적이고, 25 내지 70개 뉴클레오타이드 정도의 보다 짧은 서열인 경향이 있다. 바람직한 실시양태에서, 상기 올리고뉴클레오타이드 또는 폴리뉴클레오타이드는 서열 번호:16 내지 서열 번호:19 및 이들에 상보적인 서열로 이루어진 군으로부터 선택되는 하나 이상의 서열에 상보적이거나 이들과 하이브리드 형성하는 서열의 9개 이상, 18개 이상 또는 25개 이상의 염기를 포함한다. 다르게는, 부동화된 올리고를 슬라이드 표면 상에서 동일 반응계 내에서 화학적으로 합성할 수 있다. 동일 반응계 내 올리고뉴클레오타이드 합성은 마이크로어레이상의 반점에 적절한 뉴클레오타이드를 연속적으로 첨가함을 포함하고, 물리적 또는 가상 마스크를 사용하여 과정의 각 단계 동안 뉴클레오타이드를 수용하지 않는 반점을 보호한다. 바람직하게는, 상기 합성된 핵산은 고정된 핵산이다.
발현 프로파일링 마이크로어레이 실험에서, 사용되는 RNA 주형은 연구되는 세포 또는 조직의 전사 프로파일을 대표한다. RNA를 먼저 비교해야 하는 세포 개체군 또는 조직으로부터 단리한다. 이어, 각 RNA 샘플을 주형으로서 사용하여 역전사 반응을 통해 형광 라벨링된 cDNA를 생성시킨다. 직접적인 라벨링 또는 간접적인 라벨링 방법에 의해, cDNA의 형광 라벨링을 달성할 수 있다. 직접적인 라벨링 동안에는, 형광 개질된 뉴클레오타이드(예컨대, Cy(등록상표)3- 또는 Cy(등록상표)5-dCTP)가 역전사 동안 cDNA 내로 직접 혼입된다. 다르게는, cDNA 합성 동안 아미노알릴-개질된 뉴클레오타이드를 혼입하고, 역전사 반응이 종결된 후 N-하이드록시석신이미드(NHS)-에스터 염료를 아미노알릴-개질된 cDNA와 컨쥬게이트화시킴으로써, 간접적인 라벨링을 달성할 수 있다. 다르게는, 프로브를 라벨링시키지 않을 수 있으나, 직접 또는 간접적으로 라벨링된 리간드와 특이적으로 결합함으로써 검출할 수 있다. 리간드(및 프로브)를 라벨링하는데 적합한 라벨 및 방법은 당해 분야에 공지되어 있으며, 예를 들어 공지 방법(예컨대, 틈새 번역 또는 키나제 처리)에 의해 혼입될 수 있는 방사성 라벨을 포함한다. 다른 적합한 라벨은 바이오틴, 형광 기, 화학 발광 기(예컨대, 다이옥세테인, 구체적으로는 유발된 다이옥세테인), 효소, 항체 등을 포함하지만 이들로 한정되지는 않는다.
분별 유전자 발현 분석을 수행하기 위하여, 상이한 RNA 샘플로부터 생성된 cDNA를 Cy(등록상표)3으로 라벨링시킨다. 생성된 라벨링된 cDNA를 정제하여 혼입되지 않은 뉴클레오타이드, 유리 염료 및 잔류 RNA를 제거한다. 정제 후, 라벨링된 cDNA 샘플을 마이크로어레이와 하이브리드 형성시킨다. 하이브리드 형성 동안 또한 세척 절차 동안 온도, 이온 강도, 시간 길이 및 폼아마이드의 농도를 비롯한 하이브리드 형성의 엄격성을 결정한다. 이들 인자는 예를 들어 샘브룩 등의 문헌[Molecular Cloning: A Laboratory Manual, 제2판, 1989]에 개괄되어 있다. 형광 마이크로어레이 스캐너를 사용하여 하이브리드 형성 후 마이크로어레이를 스캔한다. 각 반점의 형광 강도는 분석되는 유전자의 발현 수준을 나타내는데, 밝은 반점은 강하게 발현된 유전자에 상응하는 한편 흐릿한 반점은 약한 발현을 나타낸다.
상을 수득한 후에는 미가공 데이터를 분석해야 한다. 먼저, 각 반점의 형광으로부터 배경 형광을 빼야 한다. 이어, 데이터를 외부에서 첨가된 핵산(바람직하게는 RNA 또는 DNA) 같은 대조용 서열 또는 관리 유전자 패널에 대해 정규화시켜, 임의의 비특이적 하이브리드 형성, 어레이 구성의 어레이 결함 또는 가변성, cDNA 라벨링, 하이브리드 형성 또는 세척을 고려한다. 데이터 정규화에 의해, 복수개의 어레이의 결과를 비교할 수 있다.
본 발명의 다른 요지는 셉틴 9(그의 모든 전사 변이형 포함), FOXL2, SARM1, VTN, PRDM6, NR2E1, FAT 및 서열 번호:160 내지 서열 번호:165로 이루어진 군으로부터 선택되는 유전자 또는 게놈 서열의 전사 수준을 측정하는 수단을 포함하는, 본 발명의 방법에 따라 환자의 암을 진단하는데 사용하기 위한 키트에 관한 것이다. 바람직한 실시양태에서, 전사 수준을 측정하는 수단은 엄격한 조건 또는 적당히 엄격한 조건하에서 셉틴 9(그의 모든 전사 변이형 포함), FOXL2, SARM1, VTN, PRDM6, NR2E1, FAT 및 서열 번호:160 내지 서열 번호:165로 이루어진 군으로부터 선택되는 유전자 또는 게놈 서열의 전사 생성물과 하이브리드 형성할 수 있는 올리고뉴클레오타이드 또는 폴리뉴클레오타이드를 포함한다. 바람직하게는, 상기 올리고뉴클레오타이드 또는 폴리뉴클레오타이드는 엄격한 조건 또는 적당히 엄격한 조건하에서 서열 번호:16 내지 서열 번호:19에 제공되는 셉틴 9(그의 모든 전사 변이형 포함), FOXL2, SARM1, VTN, PRDM6, NR2E1, FAT 및 서열 번호:160 내지 서열 번호:165로 이루어진 군으로부터 선택되는 유전자 또는 게놈 서열의 전사 생성물중 하나 이상과 하이브리드 형성할 수 있다. 한 실시양태에서, 상기 올리고뉴클레오타이드 또는 폴리뉴클레오타이드는 서열 번호:16 내지 서열 번호:19 및 이들에 상보적인 서열로 이루어진 군으로부터 선택되는 하나 이상의 서열에 상보적이거나 상기 서열과 하이브리드 형성하는 서열의 9개 이상, 18개 이상 또는 25개 이상의 염기를 포함한다.
가장 바람직한 실시양태에서는, 노던 블롯 분석, 역전사효소 PCR, 실시간 PCR, RNAse 보호 및 마이크로어레이의 군으로부터 선택되는 기법에 의해 전사 수준을 결정한다. 본 발명의 다른 실시양태에서, 키트는 환자의 생물학적 샘플을 수득하기 위한 수단을 추가로 포함한다. 가장 바람직하게는 전사 수준을 측정하기 위한 수단 및 환자의 생물학적 샘플을 함유하는데 적합한 용기를 추가로 포함하는 키트가 바람직하고, 가장 바람직하게는 키트 결과물의 사용 및 해석을 위한 설명서를 추가로 포함한다.
바람직한 실시양태에서, 키트는 (a) 엄격하거나 또는 적당히 엄격한 조건하에서 셉틴 9(그의 모든 전사 변이형 포함), FOXL2, SARM1, VTN, PRDM6, NR2E1, FAT 및 서열 번호:160 내지 서열 번호:165로 이루어진 군으로부터 선택되는 하나 이상의 유전자 또는 게놈 서열의 전사 생성물과 하이브리드 형성할 수 있는 복수개의 올리고뉴클레오타이드 또는 폴리뉴클레오타이드; (b) 바람직하게는 올리고뉴클레오타이드 또는 폴리뉴클레오타이드 및 전사 생성물을 포함하는 환자의 생물학적 샘플을 함유하는데 적합한 용기(이 때, 상기 올리고뉴클레오타이드 또는 폴리뉴클레오타이드는 엄격하거나 적당히 엄격한 조건하에서 전사 생성물과 하이브리드 형성할 수 있음); (c) (b)의 하이브리드 형성을 검출하는 수단; 및 임의적으로 (d) 키트 결과물의 사용 및 해석을 위한 설명서를 포함한다. (a)의 상기 올리고뉴클레오타이드 또는 폴리뉴클레오타이드가 각각의 경우 서열 번호:16 내지 서열 번호:19 및 이들에 상보적인 서열로 이루어진 군으로부터 선택되는 하나 이상의 서열에 상보적이거나 이들 서열과 하이브리드 형성할 수 있는 9개 이상, 18개 이상 또는 25개 이상의 염기를 포함하는 것이 또한 바람직하다.
키트는 또한 별도의 용기에 포장된 하이브리드 형성 완충액(올리고뉴클레오타이드가 프로브로서 사용되는 경우) 같은 다른 성분도 함유할 수 있다. 다르게는, 표적 영역을 증폭시키는데 올리고뉴클레오타이드를 사용하는 경우, 키트는 폴리머라제에 의해 매개되는 프라이머 연장(예: PCR)에 최적화된 폴리머라제 및 반응 완충액(이들은 별도의 용기에 포장됨)을 함유할 수 있다. 바람직하게는, 상기 폴리머라제는 역전사효소이다. 상기 키트가 RNase 시약을 추가로 함유하는 것이 또한 바람직하다.
본 발명은 환자로부터 수득된 샘플에서 상기 유전자 서열에 의해 코딩되는 폴리펩타이드의 존재를 검출하는 방법을 추가로 제공한다.
셉틴 9(그의 모든 전사 변이형 포함), FOXL2, SARM1, VTN, PRDM6, NR2E1, FAT 및 서열 번호:160 내지 서열 번호:165로 이루어진 군으로부터 선택되는 유전자 또는 게놈 서열에 의해 코딩되는 폴리펩타이드의 폴리펩타이드 발현의 이상 수준은 암의 존재와 관련이 있다.
본 발명에 따라, 상기 폴리펩타이드의 저발현은 암의 존재와 연관된다. 상기 폴리펩타이드가 셉틴 9 유전자로부터 전사된 서열 번호:20 내지 서열 번호:23 폴리펩타이드에 제공되는 아미노산 서열중 하나 이상에 따르는 것이 특히 바람직하다.
폴리펩타이드를 검출하기 위해 당해 분야에 공지되어 있는 임의의 방법을 이용할 수 있다. 이러한 방법은 질량-분석법, 면역 확산, 면역 전기 영동, 면역화학적 방법, 결합제-리간드 분석법, 면역조직화학적 기법, 응집 및 보체 분석법을 포함하지만, 이들로 한정되지는 않는다[예컨대, 본원에 참고로 인용된 Basic and Clinical Immunology, 사이츠 및 터 편집, Appleton & Lange, 코넥티컷주 노웍, pp 217-262, 1991 참조]. 항원결정기 또는 항원결정기들과 항체를 반응시키고 라벨링된 폴리펩타이드 또는 그의 유도체를 경쟁적으로 치환시킴을 포함하는 결합제-리간드 면역 분석법이 바람직하다.
본 발명의 특정 실시양태는 셉틴 9(그의 모든 전사 변이형 포함), FOXL2, SARM1, VTN, PRDM6, NR2E1, FAT 및 서열 번호:160 내지 서열 번호:165로 이루어진 군으로부터 선택되는 유전자 또는 게놈 서열에 의해 코딩되는 폴리펩타이드에 특이적인 항체의 사용을 포함한다. 상기 폴리펩타이드가 서열 번호:20 내지 서열 번호:23에 제공되는 아미노산 서열중 하나 이상에 따르는 것이 특히 바람직하다.
이러한 항체는 암 진단에 유용하다. 특정 실시양태에서는, 항원으로서 서열 번호:20 내지 서열 번호:23의 폴리펩타이드에 의해 코딩되는 항원결정기를 사용함으로써 단클론 또는 다클론 항체의 생성을 유도할 수 있다. 이러한 항체를 다시 암 진단용 마커로서 발현된 폴리펩타이드를 검출하는데 사용할 수 있다. 존재하는 이러한 폴리펩타이드의 수준을 통상적인 방법에 의해 정량할 수 있다. 형광 또는 방사성 리간드를 사용한 라벨링 같은 당해 분야에 공지되어 있는 다양한 수단에 의해 항체-폴리펩타이드 결합을 검출 및 정량할 수 있다. 본 발명은 상기 언급된 절차를 수행하기 위한 키트를 추가로 포함하며, 이러한 키트는 조사된 폴리펩타이드에 특이적인 항체를 함유한다.
다수의 경쟁적인 폴리펩타이드 결합 면역 분석법 및 비-경쟁적인 폴리펩타이드 결합 면역 분석법이 당해 분야에 널리 공지되어 있다. 이러한 분석법에 사용되는 항체는 예컨대 응집 시험에 사용되는 바와 같이 라벨링되지 않을 수 있거나, 또는 매우 다양한 분석 방법을 사용하기 위해 라벨링될 수 있다. 사용될 수 있는 라벨은 방사성 핵종, 효소, 형광체, 화학 발광체, 효소 기질 및 보조-인자, 효소 저해제, 입자, 염료 등을 포함한다. 바람직한 분석법은 방사성 면역 분석법( RIA ), 효소 면역 분석법, 예를 들어 효소-결합 면역 흡수 분석법(ELISA), 형광 면역 분석법 등을 포함하지만 이들로 국한되지는 않는다. 당해 분야에 공지되어 있는 다수의 방법중 임의의 방법에 의해 면역 분석법에 사용하기 위한 다클론 또는 단클론 항체 또는 이들의 항원결정기를 제조할 수 있다.
방법의 다른 실시양태에서는, 웨스턴 블롯 분석에 의해 단백질을 검출할 수 있다. 상기 분석은 당해 분야에서 기준이며, 간략히 전기 영동, 예컨대 SDS-PAGE에 의해 단백질을 분리한다. 이어, 분리된 단백질은 전기 영동에 의해 달성되는 공간상 거리를 유지하면서 적합한 막(또는 종이), 예컨대 나이트로셀룰로즈로 전달된다. 이어, 막을 차단제와 함께 배양하여 나머지 점착성 위치를 막에 결합시키며, 통상적인 사용되는 차단제는 일반적인 단백질(예: 유단백)을 포함한다. 이어, 흥미 있는 단백질에 특이적인 항체를 첨가하고, 상기 항체는 예컨대 염료 또는 효소 수단(예: 알칼리성 포스파타제 또는 고추냉이 퍼옥시다제)에 의해 검출가능하게 라벨링된다. 이어, 막 상에서의 항체의 위치를 검출한다.
방법의 다른 실시양태에서는, 면역조직화학적 수단(샘플 내에서 특이적인 항원을 조사하기 위해 항체를 사용함)에 의해 단백질을 검출할 수 있다. 상기 분석은 당해 분야에서 기준이며, 조직에서의 항원의 검출은 면역조직화학으로서 공지되어 있는 반면, 배양된 세포에서의 검출은 일반적으로 면역세포화학이라고 칭해진다. 간단히, 일차 항체는 그의 특이적인 항원에 결합함으로써 검출된다. 이어, 항체-항원 착체가 이차 효소 컨쥬게이트된 항체에 의해 결합된다. 필요한 기질 및 색원체의 존재하에, 결합된 효소는 항체-항원 결합 부위에서 착색된 침착물에 따라 검출된다. 광범위한 적합한 샘플 유형, 항원-항체 친화력, 항체 유형 및 검출 향상 방법이 존재한다. 그러므로, 각각의 개별 경우에 대해 당해 분야의 숙련자가 면역조직화학적 또는 면역세포화학적 검출의 최적 조건을 결정해야 한다.
폴리펩타이드에 대해 항체를 제조하기 위한 한가지 접근법은 폴리펩타이드중 전부 또는 일부의 아미노산 서열의 선택 및 제조, 아미노산 서열의 화학적 합성 및 적절한 동물, 통상적으로는 토끼 또는 마우스로의 그의 주입이다[밀스타인(Milstein) 및 콜러(Kohler) Nature 256:495-497, 1975; 걸프리(Gulfre) 및 밀스타인, Methods in Enzymology: Immunochemical Techniques 73:1-46, 랑곤 및 바나티스 편집, Academic Press, 1981, 본원에 참고로 인용됨]. 폴리펩타이드 또는 그의 항원결정기의 제조 방법은 화학적 합성, 재조합 DNA 기법 또는 생물학적 샘플로부터의 단리를 포함하지만 이들로 한정되지는 않는다.
방법의 최종 단계에서는, 환자의 진단을 결정하는데, (셉틴 9(그의 모든 전사 변이형 포함), FOXL2, SARM1, VTN, PRDM6, NR2E1, FAT 및 서열 번호:160 내지 서열 번호:165로 이루어진 군으로부터 선택되는 하나 이상의 유전자 또는 게놈 서열의) 저발현은 암의 존재의 지표이다. 용어 저발현은 평균치, 중간치 또는 최적화된 역치로 이루어진 군으로부터 선택될 수 있는 소정 컷 오프 미만의 검출 수준의 발현을 의미한다.
본 발명의 다른 요지는 셉틴 9(그의 모든 전사 변이형 포함), FOXL2, SARM1, VTN, PRDM6, NR2E1, FAT 및 서열 번호:160 내지 서열 번호:165로 이루어진 군으로부터 선택되는 하나 이상의 유전자 또는 게놈 서열의 폴리펩타이드를 검출하기 위한 수단을 포함하는, 본 발명의 방법에 따라 환자에서 암을 진단하는데 사용하기 위한 키트를 제공한다. 바람직하게는, 상기 폴리펩타이드의 서열은 서열 번호:20 내지 서열 번호:23에 제공된다. 폴리펩타이드를 검출하는 수단은 바람직하게는 항체, 항체 유도체 또는 항체 단편을 포함한다. 라벨링된 항체를 사용하는 웨스턴 블롯팅에 의해 폴리펩타이드를 가장 바람직하게 검출한다. 본 발명의 다른 실시양태에서, 키트는 환자의 생물학적 샘플을 수득하기 위한 수단을 추가로 포함한다. 환자의 생물학적 샘플에서 폴리펩타이드를 검출하기 위한 수단을 함유하는데 적합한 용기를 추가로 포함하는 키트가 바람직하고, 키트 결과물의 사용 및 해석을 위한 설명서를 추가로 포함하는 키트가 가장 바람직하다. 바람직한 실시양태에서 키트는 (a) 셉틴 9(그의 모든 전사 변이형 포함), FOXL2, SARM1, VTN, PRDM6, NR2E1, FAT 및 서열 번호:160 내지 서열 번호:165로 이루어진 군으로부터 선택되는 하나 이상의 유전자 또는 게놈 서열의 폴리펩타이드를 검출하기 위한 수단; (b) 상기 수단 및 폴리펩타이드를 포함하는 환자의 생물학적 샘플을 함유하는데 적합한 용기(이 때, 상기 수단은 폴리펩타이드와 착체를 형성할 수 있음); (c) (b)의 착체를 검출하는 수단; 및 임의적으로 (d) 키트 결과물의 사용 및 해석을 위한 설명서를 포함한다. 셉틴 9(그의 모든 전사 변이형 포함), FOXL2, SARM1, VTN, PRDM6, NR2E1, FAT 및 서열 번호:160 내지 서열 번호:165로 이루어진 군으로부터 선택되는 하나 이상의 유전자 또는 게놈 서열의 폴리펩타이드를 검출하기 위한 상기 수단이 서열 번호:20 내지 서열 번호:23으로부터 선택되는 폴리펩타이드 서열중 하나 이상에 특이적인 것이 바람직하다. 키트는 또한 별도의 용기에 포장된, 차단, 세척 또는 코팅에 적합한 완충액 또는 용액 같은 다른 성분도 함유할 수 있다.
본 발명의 특정 실시양태는 간 및/또는 직장결장 세포 증식 질환의 정밀한 검출, 특징 결정 및/또는 치료를 가능케 하는 상기 서열 내에서의 메틸화 수준 및/또는 패턴의 분석의 새로운 용도를 제공한다. 암의 조기 검출은 질환 예후 판정에 직접 연결되어 있고, 이에 의해 개시된 방법은 내과의 및 환자가 더욱 우수하고 더욱 지식에 근거한 치료 결정을 내릴 수 있도록 한다.
추가적인 개선
본 발명은 게놈 서열 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167의 신규 용도를 제공한다. 추가의 실시양태는 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167의 개질된 변이형, 및 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167 내에서의 시토신 메틸화 패턴의 분석을 위한 올리고뉴클레오타이드 및/또는 PNA-올리고머를 제공한다.
본 발명의 목적은 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167 및 이들에 상보적인 서열로 이루어진 군으로부터 선택되는 하나 이상의 서열 내에서 하나 이상의 CpG 다이뉴클레오타이드의 메틸화 상태를 분석함을 포함한다.
개시된 발명은 게놈 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167로부터 유도되는 처리된 핵산을 제공하는데, 이 처리는 게놈 DNA 서열의 하나 이상의 메틸화되지 않은 시토신 염기를 우라실 또는 하이브리드 형성 면에서 시토신과 검출가능하게 상이한 다른 염기로 전환시키는데 적합하다. 해당 게놈 서열은 하나 이상의 연속적인 메틸화된 CpG 위치를 포함할 수 있다. 상기 처리는 바람직하게는 바이설파이트, 아황산수소, 다이설파이트 및 이들의 조합으로 이루어진 군으로부터 선택되는 시약의 사용을 포함한다. 본 발명의 바람직한 실시양태에서, 본 발명은 서열 번호:10 내지 서열 번호:15, 서열 번호:28 내지 서열 번호:33, 서열 번호:30 내지 서열 번호:31, 서열 번호:42 내지 서열 번호:43, 서열 번호:38 내지 서열 번호:39, 서열 번호:50 내지 서열 번호:51, 서열 번호:168 내지 서열 번호:203으로 이루어진 군으로부터 선택되는 서열의 길이 16개 이상의 연속적인 뉴클레오타이드 염기의 길이를 갖는 서열을 포함하는 비-천연 발생 개질된 핵산을 제공한다. 본 발명의 다른 바람직한 실시양태에서, 상기 핵산은 서열 번호:10 내지 서열 번호:15, 서열 번호:28 내지 서열 번호:33, 서열 번호:30 내지 서열 번호:31, 서열 번호:42 내지 서열 번호:43, 서열 번호:38 내지 서열 번호:39, 서열 번호:50 내지 서열 번호:51, 서열 번호:168 내지 서열 번호:203에 개시되는 핵산 서열의 염기 쌍 50개 이상, 100개 이상, 150개 이상, 200개 이상, 250개 이상 또는 500개 이상의 길이를 갖는 구획이다. 특히 바람직한 것은 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167 또는 다른 천연 발생 DNA가 아닌, 서열 번호:10 내지 서열 번호:15, 서열 번호:28 내지 서열 번호:33, 서열 번호:30 내지 서열 번호:31, 서열 번호:42 내지 서열 번호:43, 서열 번호:38 내지 서열 번호:39, 서열 번호:50 내지 서열 번호:51, 서열 번호:168 내지 서열 번호:203의 전부 또는 일부와 동일하지 않거나 또는 상보적인 핵산 분자이다.
상기 서열이 하나 이상의 CpG, TpA 또는 CpA 다이뉴클레오타이드 및 이들에 상보적인 서열을 포함하는 것이 바람직하다. 서열 번호:10 내지 서열 번호:15, 서열 번호:28 내지 서열 번호:33, 서열 번호:30 내지 서열 번호:31, 서열 번호:42 내지 서열 번호:43, 서열 번호:38 내지 서열 번호:39, 서열 번호:50 내지 서열 번호:51, 서열 번호:168 내지 서열 번호:203의 서열은 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167에 따른 핵산의 비-천연 발생 개질된 형태를 제공하며, 각 게놈 서열의 개질은 다음과 같이 상기 게놈 서열과는 별개의 독특한 서열을 갖는 핵산을 합성시킨다. 각각의 센스 가닥 게놈 DNA, 예컨대 서열 번호:1의 경우, 4가지의 전환된 형태가 개시된다. 첫번째 형태에서는 "C"는 "T"로 전환되지만 "CpG"는 "CpG"로 유지되고(즉, 게놈 서열에 있어서 CpG 다이뉴클레오타이드 서열의 모든 "C" 잔기가 메틸화되고 따라서 전환되지 않는 경우에 상응함); 두번째 형태는 "C"는 "T"로 전환되지만 "CpG"는 "CpG"로 유지되는(즉, CpG 다이뉴클레오타이드 서열의 모든 "C" 잔기가 메틸화되고, 따라서 전환되지 않는 경우에 상응함) 개시된 게놈 DNA 서열(즉, 안티센스 가닥)의 보체를 개시한다. 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167의 '상향 메틸화된' 전환된 서열은 서열 번호:10 내지 서열 번호:15, 서열 번호:30 내지 서열 번호:31, 서열 번호:38 내지 서열 번호:39, 서열 번호:168 내지 서열 번호:185에 상응한다. "CpG" 다이뉴클레오타이드 서열의 "C" 잔기를 비롯한 모든 "C" 잔기에 있어서 "C"가 "T"로 전환되는(즉, 게놈 서열에 있어서, CpG 다이뉴클레오타이드 서열의 모든 "C" 잔기가 메틸화되지 않은 경우에 해당됨) 각 게놈 서열의 세번째 화학적으로 전환된 형태가 제공되며; 각 서열의 화학적으로 전환된 마지막 형태는 "CpG" 다이뉴클레오타이드 서열의 "C" 잔기를 비롯한 모든 "C" 잔기에 있어서 "C"가 "T"로 전환되는(즉, 각 게놈 서열의 보체(안티센스 가닥)에 있어서, CpG 다이뉴클레오타이드 서열의 모든 "C" 잔기가 메틸화되지 않은 경우에 해당됨) 개시된 게놈 DNA 서열의 보체(즉, 안티센스 가닥)를 개시한다. 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167의 '하향 메틸화된' 전환된 서열은 서열 번호:28 내지 서열 번호:33, 서열 번호:42 내지 서열 번호:43, 서열 번호:50 내지 서열 번호:51, 서열 번호:186 내지 서열 번호:203에 상응한다.
중요하게는, 이전에는, 서열 번호:10 내지 서열 번호:15, 서열 번호:28 내지 서열 번호:33, 서열 번호:30 내지 서열 번호:31, 서열 번호:42 내지 서열 번호:43, 서열 번호:38 내지 서열 번호:39, 서열 번호:50 내지 서열 번호:51, 서열 번호:168 내지 서열 번호:203에 따른 핵산 서열 및 분자는 세포 증식 질환의 검출, 분류 또는 치료에 연루되거나 연관되지 않았다.
다른 바람직한 실시양태에서, 본 발명은 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167, 서열 번호:10 내지 서열 번호:15, 서열 번호:28 내지 서열 번호:33, 서열 번호:30 내지 서열 번호:31, 서열 번호:42 내지 서열 번호:43, 서열 번호:38 내지 서열 번호:39, 서열 번호:50 내지 서열 번호:51, 서열 번호:168 내지 서열 번호:203에 따른 게놈 또는 처리된(화학적으로 개질된) DNA 내에서 시토신 메틸화 상태를 검출하기 위한 본 발명의 방법에 사용하기 적합한 올리고뉴클레오타이드 또는 올리고머를 추가로 제공한다. 상기 올리고뉴클레오타이드 또는 올리고머 핵산은 신규 진단 수단을 제공한다. 상기 올리고뉴클레오타이드 또는 올리고머는 서열 번호:10 내지 서열 번호:15, 서열 번호:28 내지 서열 번호:33, 서열 번호:30 내지 서열 번호:31, 서열 번호:42 내지 서열 번호:43, 서열 번호:38 내지 서열 번호:39, 서열 번호:50 내지 서열 번호:51, 서열 번호:168 내지 서열 번호:203에 따른 처리된 핵산 서열 및/또는 이들에 상보적인 서열, 또는 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167에 따른 게놈 서열 및/또는 이들에 상보적인 서열과 동일하거나, 적당히 엄격하거나 엄격한 조건(상기 본원에 정의된 바와 같음)하에서 상기 서열과 하이브리드 형성하는 뉴클레오타이드 9개 이상의 길이를 갖는 핵산 서열을 포함한다.
그러므로, 본 발명은 적당히 엄격하고/하거나 엄격한 하이브리드 형성 조건하에서 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167, 서열 번호:10 내지 서열 번호:15, 서열 번호:28 내지 서열 번호:33, 서열 번호:30 내지 서열 번호:31, 서열 번호:42 내지 서열 번호:43, 서열 번호:38 내지 서열 번호:39, 서열 번호:50 내지 서열 번호:51, 서열 번호:168 내지 서열 번호:203으로 이루어진 군으로부터 선택되는 서열중 전부 또는 일부 또는 이들의 보체와 하이브리드 형성하는 핵산 분자(예컨대, 올리고뉴클레오타이드 및 펩타이드 핵산(PNA) 분자(PNA-올리고머))를 포함한다. 특히 바람직한 것은 적당히 엄격하고/하거나 엄격한 하이브리드 형성 조건 하에서 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167 또는 다른 인간 게놈 DNA가 아닌, 서열 번호:10 내지 서열 번호:15, 서열 번호:28 내지 서열 번호:33, 서열 번호:30 내지 서열 번호:31, 서열 번호:42 내지 서열 번호:43, 서열 번호:38 내지 서열 번호:39, 서열 번호:50 내지 서열 번호:51, 서열 번호:168 내지 서열 번호:203의 서열중 전부 또는 일부와 하이브리드 형성하는 핵산 분자이다.
하이브리드 형성 핵산의 동일한 부분 또는 하이브리드 형성 부분은 전형적으로 뉴클레오타이드 9개 이상, 16개 이상, 20개 이상, 25개 이상, 30개 이상 또는 35개 이상의 길이를 갖는다. 그러나, 더 긴 분자도 본 발명의 효용을 갖고, 따라서 본 발명의 영역에 속한다.
바람직하게는, 본 발명의 하이브리드 형성 핵산의 하이브리드 형성 부분은 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167, 서열 번호:10 내지 서열 번호:15, 서열 번호:28 내지 서열 번호:33, 서열 번호:30 내지 서열 번호:31, 서열 번호:42 내지 서열 번호:43, 서열 번호:38 내지 서열 번호:39, 서열 번호:50 내지 서열 번호:51, 서열 번호:168 내지 서열 번호:203으로 이루어진 군으로부터 선택되는 서열 또는 이의 일부, 또는 이들의 보체와 95% 이상, 또는 98% 이상, 또는 100% 동일하다.
본원에 기재된 유형의 하이브리드 형성 핵산을 예컨대 프라이머(예: PCR 프라이머) 또는 진단용 및/또는 예후 판정용 프로브 또는 프라이머로서 사용할 수 있다. 바람직하게는, 핵산 샘플과 올리고뉴클레오타이드 프로브의 하이브리드 형성은 엄격한 조건하에 수행하고, 프로브는 표적 서열과 100% 동일하다. 핵산 이중 가닥 또는 하이브리드 안정성은 프로브가 표적 DNA로부터 분리되는 온도인 융점 또는 Tm으로서 표현된다. 이 융점을 이용하여 요구되는 엄격성 조건을 한정한다.
서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167의 상응하는 서열과 관련되어 있고 동일하기보다는 실질적으로 동일한 표적 서열(예컨대, 대립 유전자 변이형 및 SNP)의 경우, 특정 농도의 염(예컨대, SSC 또는 SSPE)을 사용하여 동종 하이브리드 형성만이 이루어지는 최저 온도를 먼저 확립하는 것이 유용하다. 이어, 1% 불일치가 Tm에서 1℃를 감소시킨다고 추정하면, 그에 따라 하이브리드 형성 반응에서의 최종 세척 온도가 감소된다(예를 들어, 프로브와 95%보다 높게 일치하는 서열이 고려되는 경우, 최종 세척 온도는 5℃만큼 감소된다). 실제로, Tm의 변화는 1% 불일치당 0.5 내지 1.5℃일 수 있다.
예컨대 서열 번호:1을 참조하여 폴리뉴클레오타이드 위치에 의해 표시되는 길이 X(뉴클레오타이드)의 본 발명의 올리고뉴클레오타이드의 예는 길이 X의 연속적으로 겹치는 올리고뉴클레오타이드의 세트(센스 및 안티센스 세트)에 상응하는 것을 포함하며, 이 때 각각의 연속적으로 겹치는 세트(소정의 X 값에 상응함) 내에서의 올리고뉴클레오타이드는 뉴클레오타이드 위치로부터 Z개의 올리고뉴클레오타이드의 한정된 세트로서 정의된다:
n 내지 (n+(X-1))
상기 식에서, n은 1, 2, 3,...(Y-(X-1))이고; Y는 서열 번호: 1의 길이(뉴클레오타이드 또는 염기 쌍)(219909)이며; X는 세트 내의 각 올리고뉴클레오타이드의 공통적인 길이(뉴클레오타이드)(예컨대, 연속적으로 겹치는 20량체의 세트의 경우 X는 20임)이며; 길이 Y의 소정 서열 번호에 있어서 길이 X의 연속적으로 겹치는 올리고머의 수(Z)는 Y-(X-1)이다.
예를 들어, X가 20인 서열 번호:1의 센스 또는 안티센스 세트의 경우 Z는 219909-19=219890이다.
바람직하게는, 세트는 하나 이상의 CpG, TpG 또는 CpA 다이뉴클레오타이드를 포함하는 올리고머로 한정된다.
본 발명의 20량체 올리고뉴클레오타이드의 예는 서열 번호:1를 참조하여 폴리뉴클레오타이드 위치에 의해 표시되는, 219890개의 올리고머의 하기 세트(및 이에 상보적인 안티센스 세트)를 포함한다:
1-20, 2-21, 3-22, 4-23, 5-24,..........및 219890-219909.
바람직하게는, 세트는 하나 이상의 CpG, TpG 또는 CpA 다이뉴클레오타이드를 포함하는 올리고머로 제한된다.
마찬가지로, 본 발명의 25량체 올리고뉴클레오타이드의 예는 서열 번호:1을 참조하여 폴리뉴클레오타이드 위치에 의해 표시되는, 219885개의 올리고머의 하기 세트(및 이에 상보적인 안티센스 세트)를 포함한다:
1-25, 2-26, 3-27, 4-28, 5-29,.........및 219885-219909.
바람직하게는, 세트는 하나 이상의 CpG, TpG 또는 CpA 다이뉴클레오타이드를 포함하는 올리고머로 한정된다.
본 발명은 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167, 서열 번호:10 내지 서열 번호:15, 서열 번호:28 내지 서열 번호:33, 서열 번호:30 내지 서열 번호:31, 서열 번호:42 내지 서열 번호:43, 서열 번호:38 내지 서열 번호:39, 서열 번호:50 내지 서열 번호:51, 서열 번호:168 내지 서열 번호:203(센스 및 안티센스) 각각에 있어서 길이 X의 올리고뉴클레오타이드 또는 개질된 올리고뉴클레오타이드의 여러 개의 연속적으로 겹치는 세트를 포괄하며, 이 때 X는 예컨대 9, 10, 17, 20, 22, 23, 25, 27, 30 또는 35 뉴클레오타이드이다.
본 발명에 따른 올리고뉴클레오타이드 또는 올리고머는 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167로 이루어진 군으로부터 선택되는 게놈 서열의 유전학적 및 후성학적 매개변수를 확인하는데 유용한 효과적인 도구를 구성한다. 길이 X의 이러한 올리고뉴클레오타이드 또는 개질된 올리고뉴클레오타이드의 바람직한 세트는 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167, 서열 번호:10 내지 서열 번호:15, 서열 번호:28 내지 서열 번호:33, 서열 번호:30 내지 서열 번호:31, 서열 번호:42 내지 서열 번호:43, 서열 번호:38 내지 서열 번호:39, 서열 번호:50 내지 서열 번호:51, 서열 번호:168 내지 서열 번호:203(및 이들의 보체)에 상응하는 올리고머의 연속적으로 겹치는 세트이다. 바람직하게는, 상기 올리고머는 하나 이상의 CpG, TpG 또는 CpA 다이뉴클레오타이드를 포함한다.
본 발명에 따른 특히 바람직한 올리고뉴클레오타이드 또는 올리고머는 CpG 다이뉴클레오타이드(또는 상응하는 전환된 TpG 또는 CpA 다이뉴클레오타이드) 서열의 시토신이 올리고뉴클레오타이드의 중간 1/3 내에 존재하는 것이다. 즉, 올리고뉴클레오타이드가 예컨대 염기 13개의 길이를 갖는 경우, CpG, TpG 또는 CpA 다이뉴클레오타이드는 5'-말단으로부터 5번째 내지 9번째 뉴클레오타이드 내에 위치한다.
하나 이상의 잔기 또는 컨쥬게이트에 올리고뉴클레오타이드를 화학적으로 연결하여 올리고뉴클레오타이드의 활성, 안정성 또는 검출을 향상시킴으로써, 본 발명의 올리고뉴클레오타이드를 또한 개질시킬 수 있다. 이러한 잔기 또는 컨쥬게이트는 발색단, 형광체, 콜레스테롤 같은 지질, 콜산, 티오에터, 지방족 쇄, 인지질, 폴리아민, 폴리에틸렌 글라이콜(PEG), 팔미틸 잔기 및 예를 들어 미국 특허 제 5,514,758 호, 제 5,565,552 호, 제 5,567,810 호, 제 5,574,142 호, 제 5,585,481 호, 제 5,587,371 호, 제 5,597,696 호 및 제 5,958,773 호에 개시된 다른 것들을 포함한다. 프로브는 또한 특히 바람직한 짝짓기 특성을 갖는 PNA(펩타이드 핵산)의 형태로 존재할 수도 있다. 따라서, 올리고뉴클레오타이드는 펩타이드 같은 다른 부착된 기를 포함할 수 있고, 하이브리드 형성-촉발되는 절단제[크롤(Krol) 등, Bio Techniques 6:958-976, 1988] 또는 삽입제(intercalating agent)[존(Zon), Pharm. Res . 5:539-549, 1988]를 포함할 수 있다. 이를 위하여, 올리고뉴클레오타이드를 다른 분자, 예를 들어 발색단, 형광체, 펩타이드, 하이브리드 형성-촉발되는 가교결합제, 이송제, 하이브리드 형성-촉발되는 절단제 등에 컨쥬게이트시킬 수 있다.
올리고뉴클레오타이드는 또한 하나 이상의 당해 분야에서 인정된 개질된 당 및/또는 염기 잔기도 포함할 수 있거나, 또는 개질된 골격 또는 비-천연 뉴클레오사이드간 연결을 포함할 수 있다.
본 발명의 특정 실시양태에 따른 올리고뉴클레오타이드 또는 올리고머는 전형적으로 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167 및 이들에, 또는 서열 번호:10 내지 서열 번호:15, 서열 번호:28 내지 서열 번호:33, 서열 번호:30 내지 서열 번호:31, 서열 번호:42 내지 서열 번호:43, 서열 번호:38 내지 서열 번호:39, 서열 번호:50 내지 서열 번호:51, 서열 번호:168 내지 서열 번호:203 및 이들에 상보적인 서열에 따른 처리된 핵산의 서열 내에서의 상응하는 CpG, TpG 또는 CpA 다이뉴클레오타이드에 상보적인 서열로 이루어진 군으로부터 선택되는 게놈 서열의 각 CpG 다이뉴클레오타이드를 분석하기 위한 하나 이상의 올리고머를 함유하는 '세트'로 사용된다. 그러나, 경제적인 요인 또는 다른 요인 때문에, 상기 서열 내의 CpG 다이뉴클레오타이드의 한정된 선택을 분석하고 그에 따라 올리고뉴클레오타이드의 세트의 내용이 변화되는 것이 바람직할 수 있는 것으로 예상된다.
그러므로, 특정 실시양태에서, 본 발명은 처리된 게놈 DNA(서열 번호:10 내지 서열 번호:15, 서열 번호:28 내지 서열 번호:33, 서열 번호:30 내지 서열 번호:31, 서열 번호:42 내지 서열 번호:43, 서열 번호:38 내지 서열 번호:39, 서열 번호:50 내지 서열 번호:51, 서열 번호:168 내지 서열 번호:203), 또는 게놈 DNA(서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167 및 그에 상보적인 서열)에서 시토신 메틸화 상태를 검출하는데 유용한 둘(2) 이상의 (올리고뉴클레오타이드 및/또는 PNA-올리고머)의 세트를 제공한다. 이들 프로브는 간 및/또는 직장결장 세포 증식 질환의 유전학적 및 후성학적 매개변수의 진단, 분류 및/또는 치료를 가능케 한다. 처리된 게놈 DNA(서열 번호:10 내지 서열 번호:15, 서열 번호:28 내지 서열 번호:33, 서열 번호:30 내지 서열 번호:31, 서열 번호:42 내지 서열 번호:43, 서열 번호:38 내지 서열 번호:39, 서열 번호:50 내지 서열 번호:51, 서열 번호:168 내지 서열 번호:203) 또는 게놈 DNA(서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167 및 이들에 상보적인 서열)에서 단일 뉴클레오타이드 다형 현상(SNP)을 검출하는 데에도 올리고머의 세트를 사용할 수 있다.
바람직한 실시양태에서는, 올리고뉴클레오타이드 세트의 하나 이상, 더욱 바람직하게는 모든 일원이 고상에 결합된다.
추가의 실시양태에서, 본 발명은 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167, 서열 번호:10 내지 서열 번호:15, 서열 번호:28 내지 서열 번호:33, 서열 번호:30 내지 서열 번호:31, 서열 번호:42 내지 서열 번호:43, 서열 번호:38 내지 서열 번호:39, 서열 번호:50 내지 서열 번호:51, 서열 번호:168 내지 서열 번호:203 및 이들에 상보적인 서열, 또는 이들의 구획중 하나의 DNA 서열을 증폭시키기 위해 '프라이머' 올리고뉴클레오타이드로서 사용되는 둘(2) 이상의 올리고뉴클레오타이드의 세트를 제공한다.
올리고뉴클레오타이드는 "DNA 칩"의 "어레이"(즉, 고상에 결합된 상이한 올리고뉴클레오타이드 및/또는 PNA-올리고머의 배열)의 전부 또는 일부를 구성할 수 있는 것으로 생각된다. 상이한 올리고뉴클레오타이드- 및/또는 PNA-올리고머 서열의 이러한 어레이는 예를 들어 직사각형 또는 육각형 격자의 형태로 고상에 배열됨을 그 특징으로 할 수 있다. 고상 표면은 규소, 유리, 폴리스타이렌, 알루미늄, 강, 철, 구리, 니켈, 은 또는 금으로 구성될 수 있다. 나이트로셀룰로즈 및 나일론 같은 플라스틱(펠렛의 형태로 또는 수지 매트릭스로서 존재할 수 있음)도 사용할 수 있다. 올리고머 어레이 제조에서의 종래 기술에 대한 개관은 문헌[Nature Genetics, Nature Genetics Supplement, Volume 21, 1999년 1월] 및 이에 인용된 문헌에서 모아볼 수 있다. 부동화된 DNA 어레이를 스캔하는데 흔히 형광 라벨링된 프로브를 사용한다. 특정 프로브의 5'-OH로의 Cy3 및 Cy5 염료의 단순 부착이 형광 라벨에 특히 바람직하다. 하이브리드 형성된 프로브의 형광 검출은 예를 들어 공초점 현미경을 통해 수행할 수 있다. 다수의 다른 염료 외에 Cy3 및 Cy5는 시판되고 있다.
또한, 올리고뉴클레오타이드 또는 그의 특정 서열이 독특한 라벨링된 프로브의 다양한 개체군의 일부로서 또는 상기 개체군과 함께 예컨대 '지정자'로서 사용되는 '가상 어레이'의 전부 또는 일부를 구성하여 분석물의 복잡한 혼합물을 분석할 수 있는 것을 생각된다. 이러한 방법은 예를 들어 US 2003/0013091(2003년 1월 16일자로 공개된 미국 특허원 제 09/898,743 호)에 기재되어 있다. 이러한 방법에서는, 복잡한 혼합물의 각 핵산(즉, 각 분석물)이 독특한 라벨에 의해 독특하게 결합되어 검출될 수 있도록(각 라벨을 직접 계수하여 혼합물중 각 분자 부류의 디지털 판독치를 생성시킴) 충분한 라벨을 생성시킨다.
본 발명에 따른 올리고머를 간 및/또는 직장결장 세포 증식 질환의 검출; 검출 및 아부류의 구별; 진단; 예후 판정; 치료; 모니터링; 및 치료 및 모니터링중 하나 이상에 이용하는 것이 특히 바람직하다. 직장결장 암종, 결장 암종, 염증성 결장 조직, 1cm 미만의 등급 2 형성이상 결장 암종, 1cm보다 큰 등급 3 형성이상 결장 암종, 정상 결장 조직, 결장이 아닌 건강한 조직 및 결장이 아닌 암 조직중 하나 이상의 검출 또는 검출 및 구별을 위해 상기 세트를 사용함으로써 이것이 가능해진다.
특히 바람직한 것은 실시예에 따른 올리고머 세트이다.
본 방법의 가장 바람직한 실시양태에서는, 세포 증식 질환, 가장 바람직하게는 종양성 세포 증식의 존재 또는 부재, 또는 양성 질환으로부터의 이의 구별을 결정한다. 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167 및 그의 보체로 이루어진 군으로부터 선택되는 서열의 16개 이상의 연속적인 뉴클레오타이드를 포함하거나 엄격한 조건하에서 상기 뉴클레오타이드와 하이브리드 형성하는, 하나 이상의 CpG 위치를 포함하는 하나 이상의 표적 서열의 메틸화 현황을 분석함으로써 이를 달성할 수 있다. 본 발명은 시토신 메틸화 및 단일 뉴클레오타이드 다형 현상을 분석함으로써 환자 내에서 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167에 따른 게놈 서열의 유전학적 및/또는 후성학적 매개변수를 확인하는 방법을 추가로 제공한다. 상기 방법은 상기 환자로부터 수득된 생물학적 샘플중의 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167을 포함하는 핵산을, 표적 핵산 내에서의 메틸화된 CpG 다이뉴클레오타이드와 메틸화되지 않은 CpG 다이뉴클레오타이드를 구분하는 하나 이상의 시약 또는 일련의 시약과 접촉시킴을 포함한다.
바람직한 실시양태에서, 상기 방법은 하기 단계를 포함한다: 첫번째 단계에서는, 분석되어야 하는 조직 샘플을 수득한다. 공급원은 세포주, 조직학적 슬라이드, 생검체, 파라핀-매립된 조직, 신체 유체, 대변, 결장 유출물, 소변, 혈장, 혈청, 전혈, 단리된 혈액 세포, 혈액으로부터 단리된 세포 및 이들의 모든 가능한 조합 같은 임의의 적합한 공급원일 수 있다. DNA의 상기 공급원이 대변 또는 결장 유출물, 소변, 혈장, 혈청, 전혈, 단리된 혈액 세포 및 혈액으로부터 단리된 세포로 이루어진 군으로부터 선택되는 신체 유체인 것이 바람직하다.
이어, 게놈 DNA를 샘플로부터 단리한다. 시판중인 키트를 사용함을 포함하는 당해 분야에서의 임의의 기준 수단에 의해 게놈 DNA를 단리할 수 있다. 간단하게, 관심 있는 DNA가 세포막에 의해 캡슐화된 경우, 생물학적 샘플을 효소적, 화학적 또는 기계적 수단에 의해 파괴 및 용해시켜야 한다. 이어, DNA 용액을 예컨대 프로테이나제 K로 소화시킴으로써 단백질 및 다른 오염물질을 제거할 수 있다. 이어, 게놈 DNA를 용액으로부터 회수한다. 염석, 유기 추출 또는 DNA의 고상 지지체로의 결합을 비롯한 다양한 방법에 의해 이를 수행할 수 있다. 방법의 선택은 시간, 비용 및 요구되는 DNA의 양을 포함한 수 가지 인자에 의해 영향을 받는다.
샘플 DNA가 막에 내포되지 않는 경우(예컨대, 혈액 샘플로부터의 순환 DNA), DNA를 단리 및/또는 정제하기 위한 당해 분야의 기준 방법을 사용할 수 있다. 이러한 방법은 단백질 변성 시약, 예를 들어 카오트로픽(chaotropic) 염(예: 구아니딘 하이드로클로라이드 또는 우레아), 또는 세제, 예를 들어 소듐 도데실 설페이트(SDS), 사이아노겐 브로마이드를 사용함을 포함한다. 다른 방법은 에탄올 침전 또는 프로판올 침전, 원심분리에 의한 진공 농축을 포함하지만 이들로 한정되지는 않는다. 당해 분야의 숙련자는 또한 필터 장치, 예컨대 한외여과, 실리카 표면 또는 막, 자기 입자, 폴리스타이롤 입자, 폴리스타이롤 표면, 양으로 하전된 표면 및 양으로 하전된 막, 하전된 막, 하전된 표면, 하전된 스위치 막, 하전된 스위치된 표면 같은 장치도 사용할 수 있다.
핵산을 추출한 후에는 게놈 이중 가닥 DNA를 분석에 사용한다.
방법의 두번째 단계에서는, 5'-위치에서 메틸화되지 않은 시토신 염기를 우라실, 티민, 또는 하이브리드 형성 거동 면에서 시토신과 상이한 다른 염기로 전환시키는 방식으로 게놈 DNA 샘플을 처리한다. 이는 본원에서 '전처리' 또는 '처리'로 이해된다.
이는 바람직하게는 바이설파이트 시약을 사용한 처리에 의해 달성된다. 용어 "바이설파이트 시약"은 메틸화된 CpG 다이뉴클레오타이드 서열과 메틸화되지 않은 CpG 다이뉴클레오타이드 서열을 구분하는 것으로 본원에 개시된 유용한 바이설파이트, 다이설파이트, 아황산수소 또는 이들의 조합을 포함하는 시약을 일컫는다. 이러한 처리 방법은 당해 분야에 공지되어 있다(예컨대, 본원에 참고로 인용된 PCT/EP2004/011715 호). n-알킬렌 글라이콜, 구체적으로는 다이에틸렌 글라이콜 다이메틸 에터(DME) 같은(이것으로 한정되지는 않음) 변성 용매의 존재하에, 또는 다이옥세인 또는 다이옥세인 유도체의 존재하에 바이설파이트 처리를 수행하는 것이 바람직하다. 바람직한 실시양태에서는, 1% 내지 35%(v/v)의 농도로 변성 용매를 사용한다. 또한, 크로메인 유도체, 예를 들어 6-하이드록시-2,5,7,8-테트라메틸크로메인 2-카복실산 또는 트라이하이드록시벤조산 및 이들의 유도체, 예컨대 갈산 같은(이들로 한정되지는 않음) 소거제의 존재하에 바이설파이트 반응을 수행하는 것도 바람직하다(본원에 참고로 인용된 PCT/EP2004/011715 호 참조). 30 내지 70℃의 반응 온도에서 바이설파이트 전환을 수행하는 것이 바람직하고, 반응 동안 단시간에 걸쳐 온도를 85℃보다 높게 올린다(본원에 참고로 인용된 PCT/EP2004/011715 호 참조). 정량하기 전에 바이설파이트 처리된 DNA를 바람직하게 정제한다. 바람직하게는 마이크로콘(Microcon)(TM) 칼럼[밀리포어(Millipore)(TM) 제품]에 의해 수행되는 한외여과 같은(이것으로 한정되지는 않음) 당해 분야에 공지된 임의의 수단에 의해 이를 수행할 수 있다. 변형된 제조업체의 절차에 따라 정제를 수행한다(본원에 참고로 인용된 PCT/EP2004/011715 호 참조).
방법의 세번째 단계에서는, 본 발명에 따른 프라이머 올리고뉴클레오타이드의 세트 및 증폭 효소를 사용하여, 처리된 DNA의 단편을 증폭시킨다. 하나의 동일한 반응 용기에서 동시에 수개의 DNA 구획의 증폭을 수행할 수 있다. 전형적으로는, 폴리머라제 연쇄 반응(PCR)을 이용하여 증폭을 수행한다. 바람직하게는, 상기 증폭물은 길이가 100 내지 2,000개의 염기 쌍이다. 프라이머 올리고뉴클레오타이드의 세트는 그 서열이 각각 서열 번호:10 내지 서열 번호:15, 서열 번호:28 내지 서열 번호:33, 서열 번호:30 내지 서열 번호:31, 서열 번호:42 내지 서열 번호:43, 서열 번호:38 내지 서열 번호:39, 서열 번호:50 내지 서열 번호:51, 서열 번호:168 내지 서열 번호:203 및 이들에 상보적인 서열중 하나의 염기 서열의 염기 쌍 16개 이상의 길이를 갖는 구획에 역 상보적이거나 동일하거나 또는 엄격하거나 매우 엄격한 조건하에서 이들 구획과 하이브리드 형성하는 둘 이상의 올리고뉴클레오타이드를 포함한다.
본 방법의 다른 실시양태에서는, 메틸화-특이적인 프라이머 올리고뉴클레오타이드를 사용함으로써 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167로 이루어진 군으로부터 선택되는 하나 이상의 핵산 서열 내에서 미리 선택된 CpG 위치의 메틸화 현황을 검출할 수 있다. 이 기법(MSP)은 허맨의 미국 특허 제 6,265,171 호에 기재된 바 있다. 바이설파이트 처리된 DNA의 증폭을 위해 메틸화 현황 특이적 프라이머를 사용하면, 메틸화된 핵산과 메틸화되지 않은 핵산을 구별할 수 있다. MSP 프라이머 쌍은 바이설파이트 처리된 CpG 다이뉴클레오타이드와 하이브리드 형성하는 하나 이상의 프라이머를 함유한다. 따라서, 상기 프라이머의 서열은 하나 이상의 CpG 다이뉴클레오타이드를 포함한다. 메틸화되지 않은 DNA에 특이적인 MSP 프라이머는 CpG 내의 C 위치에 "T"를 함유한다. 따라서, 바람직하게는, 상기 프라이머의 염기 서열은 서열 번호:10 내지 서열 번호:15, 서열 번호:28 내지 서열 번호:33, 서열 번호:30 내지 서열 번호:31, 서열 번호:42 내지 서열 번호:43, 서열 번호:38 내지 서열 번호:39, 서열 번호:50 내지 서열 번호:51, 서열 번호:168 내지 서열 번호:203 및 이들에 상보적인 서열중 하나에 따른 처리된 핵산 서열과 하이브리드 형성하는 뉴클레오타이드 9개 이상의 길이를 갖는 서열을 포함해야 하며, 이 때 상기 올리고머의 염기 서열은 하나 이상의 CpG 다이뉴클레오타이드를 포함한다. 본 방법의 다른 바람직한 실시양태는 차단체 올리고뉴클레오타이드의 사용(헤비메틸™ 분석법)을 포함한다. 이러한 차단체 올리고뉴클레오타이드의 사용은 유(Yu) 등의 문헌[Bio Techniques 23:714-720, 1997]에 기재된 바 있다. PCR 프라이머와 동시에 차단 프로브 올리고뉴클레오타이드를 바이설파이트 처리된 핵산과 하이브리드 형성시킨다. 차단 프로브의 상보적인 서열이 존재하는 경우 핵산의 증폭이 억제되도록, 차단 프로브의 5' 위치에서 핵산의 PCR 증폭을 종결시킨다. 프로브는 메틸화 현황 특이적인 방식으로 바이설파이트 처리된 핵산과 하이브리드 형성하도록 디자인될 수 있다. 예를 들어, 메틸화되지 않은 핵산의 개체군 내에서 메틸화된 핵산을 검출하기 위하여, 메틸화된 핵산의 증폭을 억제해야 하는 경우의 'CpG'와 대조적으로 해당 위치에 'CpA' 또는 'TpA'를 포함하는 차단 프로브를 사용함으로써, 해당 위치에서 메틸화되지 않은 핵산의 증폭을 억제한다.
차단체 올리고뉴클레오타이드를 사용하는 PCR 방법의 경우, 폴리머라제-매개되는 증폭을 효율적으로 방해하기 위해서는 차단체 올리고뉴클레오타이드가 폴리머라제에 의해 연장되지 않아야 한다. 바람직하게는, 3'-데옥시올리고뉴클레오타이드 또는 "유리" 하이드록실기 이외의 것으로 3'-위치에서 유도화된 올리고뉴클레오타이드인 차단체를 사용함으로써 이를 달성한다. 예를 들어, 3'-O-아세틸 올리고뉴클레오타이드가 바람직한 차단체 분자 부류의 대표이다.
또한, 차단체 올리고뉴클레오타이드의 폴리머라제-매개되는 분해를 배제해야 한다. 바람직하게는, 이러한 배제는 5'-3' 엑소뉴클레아제 활성을 갖지 않는 폴리머라제의 사용, 또는 예컨대 차단체 분자를 뉴클레아제-내성으로 만드는 그의 5'-말단에 예컨대 티오에이트 가교를 갖는 개질된 차단체 올리고뉴클레오타이드의 사용을 포함한다. 특정 용도에서는 차단체의 이러한 5' 개질을 요구하지 않을 수 있다. 예를 들어, 차단체- 및 프라이머-결합 부위가 겹침에 의해 프라이머의 결합(예컨대, 과량의 차단체와)이 배제되면, 차단체 올리고뉴클레오타이드의 열화가 실질적으로 배제된다. 이는, 폴리머라제가 프라이머를 전방으로 또한 차단체를 통해(5'-3' 방향으로) 연장(이 과정은 통상 하이브리드 형성된 차단체 올리고뉴클레오타이드를 열화시킴)시키지 않기 때문이다.
본 발명에서 또한 본원에서 구체화되는 바와 같이, 특히 바람직한 차단체/PCR 실시양태는 차단 올리고뉴클레오타이드로서 펩타이드 핵산(PNA) 올리고머의 사용을 포함한다. 이러한 PNA 차단체 올리고머는 폴리머라제에 의해 분해되지도 연장되지도 않기 때문에 이상적으로 적합하다.
바람직하게는, 그러므로, 상기 차단 올리고뉴클레오타이드의 염기 서열은 서열 번호:10 내지 서열 번호:15, 서열 번호:28 내지 서열 번호:33, 서열 번호:30 내지 서열 번호:31, 서열 번호:42 내지 서열 번호:43, 서열 번호:38 내지 서열 번호:39, 서열 번호:50 내지 서열 번호:51, 서열 번호:168 내지 서열 번호:203 및 이들에 상보적인 서열중 하나에 따른 처리된 핵산 서열과 하이브리드 형성하는 뉴클레오타이드 9개 이상의 길이를 갖는 서열을 포함해야 하며, 이 때 상기 올리고뉴클레오타이드의 염기 서열은 하나 이상의 CpG, TpG 또는 CpA 다이뉴클레오타이드를 포함한다.
증폭에 의해 수득되는 단편은 직접 또는 간접적으로 검출가능한 라벨을 가질 수 있다. 형광 라벨, 방사성 핵종, 또는 질량 분석법에서 검출될 수 있는 전형적인 질량을 갖는 떼어질 수 있는 분자 단편 형태의 라벨이 바람직하다. 상기 라벨이 질량 라벨인 경우, 라벨링된 증폭물이 단일 순 양전하 또는 음전하를 가져 질량 분석계에서 더욱 우수하게 검출될 수 있는 것이 바람직하다. 예를 들어 매트릭스 보조되는 레이저 탈착(desorption)/이온화 질량 분석법(MALDI)에 의해 또는 전자 분무 질량 분석법(ESI)을 이용하여 검출을 수행할 수 있고 가시화할 수 있다.
매트릭스 보조되는 레이저 탈착/이온화 질량 분석법(MALDI-TOF)은 생체 분자의 분석을 위한 가장 효율적인 발전이다[카라스(Karas) 및 힐렌캠프(Hillenkamp), Anal. Chem ., 60:2299-301, 1988]. 분석물을 광-흡수 매트릭스에 매립시킨다. 짧은 레이저 펄스에 의해 매트릭스를 증발시켜, 분석물 분자를 단편화되지 않는 방식으로 기상으로 운송한다. 매트릭스 분자와 충돌시킴으로써 분석물을 이온화시킨다. 인가된 전압은 이온을 자기장-비함유 비행 관 내로 가속화시킨다. 상이한 질량 때문에, 이온은 상이한 속도로 가속화된다. 보다 작은 이온은 더 큰 이온보다 검출기에 더 빨리 도달한다. MALDI-TOF 분광법은 펩타이드 및 단백질의 분석에 아주 적합하다. 핵산의 분석은 다소 더 어렵다[구트(Gut) 및 벡(Beck), Current Innovations and Future Trends, 1:147-57, 1995]. 핵산 분석에 관한 민감도는 펩타이드의 경우보다 약 100배 더 낮고, 단편 크기가 증가함에 따라 불균형적으로 감소한다. 뿐만 아니라, 음으로 다중 하전된 골격을 갖는 핵산의 경우, 매트릭스를 통한 이온화 과정이 상당히 덜 효율적이다. MALDI-TOF 분광법에서는, 매트릭스의 선택이 탁월하게 중요한 역할을 한다. 펩타이드의 탈착을 위해, 매우 미세한 결정화를 생성시키는 수 가지의 매우 효율적인 매트릭스를 발견하였다. 이제, DNA에 응답하는 수 가지 매트릭스가 존재하지만, 펩타이드와 핵산 사이의 민감도 차이는 감소되지 못하였다. 그러나, DNA를 펩타이드와 더욱 유사해지도록 하는 방식으로 화학적으로 개질시킴으로써 이러한 민감도 차이를 감소시킬 수 있다. 예를 들어, 골격의 통상적인 포스페이트가 티오포스페이트로 치환된 포스포로티오에이트 핵산을, 단일 알킬화 화학을 이용하여 전하-중성 DNA로 전환시킬 수 있다[구트 및 벡, Nucleic Acids Res . 23:1367-73, 1995]. 이 개질된 DNA로의 전하 택의 연결은 MALDI-TOF 민감도를 펩타이드의 경우에 발견되는 것과 동일한 수준으로 증가시킨다. 전하 택의 추가적인 이점은 불순물(이는 개질되지 않은 기질의 검출을 상당히 더 어렵게 만듦)에 대해 분석의 안정성을 증가시키는 것이다.
본 방법의 네번째 단계에서는, 처리하기 전에 CpG 다이뉴클레오타이드의 메틸화 현황을 확인하기 위하여 본 방법의 세번째 단계 동안 수득된 증폭물을 분석한다.
MSP 증폭에 의해 증폭물을 수득하는 실시양태에서는, 증폭물의 존재 또는 부재가 그 자체로 상기 프라이머의 염기 서열에 따라 프라이머에 의해 커버되는 CpG 위치의 메틸화 상태의 지표이다.
표준 PCR 및 메틸화 특이적 PCR 둘 다에 의해 수득된 증폭물을, 어레이 기법 및 프로브에 기초한 기법 뿐만 아니라 서열 결정 및 주형 유도되는 연장 같은(이들로 한정되지는 않음) 염기-염기 방법에 의해 추가로 분석할 수 있다.
본 방법의 한 실시양태에서는, 세번째 단계에서 합성된 증폭물을 올리고뉴클레오타이드 및/또는 PNA 프로브의 어레이 또는 세트와 후속 하이브리드 형성시킨다. 이와 관련하여, 하이브리드 형성은 다음 방식으로 이루어진다: 하이드리드 형성 동안 사용되는 프로브 세트는 바람직하게는 둘 이상의 올리고뉴클레오타이드 또는 PNA-올리고머로 구성되며; 방법에서, 증폭물은 고상에 미리 결합된 올리고뉴클레오타이드와 하이브리드 형성하는 프로브로서 작용하며; 하이브리드 형성되지 않은 단편을 후속 제거하고; 상기 올리고뉴클레오타이드는 본 서열 목록에 명시된 염기 서열의 구획에 역 상보적이거나 동일한 뉴클레오타이드 9개 이상의 길이를 갖는 하나 이상의 염기 서열을 함유하며; 구획은 하나 이상의 CpG, TpG 또는 CpA 다이뉴클레오타이드를 포함한다. 하이브리드 형성 핵산의 하이브리드 형성 부위는 전형적으로는 뉴클레오타이드 9개 이상, 15개 이상, 20개 이상, 25개 이상, 30개 이상 또는 35개 이상의 길이를 갖는다. 그러나, 더 긴 분자도 본 발명의 효용을 가지며, 따라서 본 발명의 영역에 속한다.
바람직한 실시양태에서, 상기 뉴클레오타이드는 올리고머의 중심 1/3에 존재한다. 예를 들어, 올리고머가 하나의 CpG 다이뉴클레오타이드를 포함하는 경우, 상기 다이클레오타이드는 바람직하게는 13-량체의 5'-말단으로부터 5번째 내지 9번째 뉴클레오타이드이다. 하나의 올리고뉴클레오타이드가 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167로 이루어진 군으로부터 선택되는 서열 내의 각 CpG 다이뉴클레오타이드, 및 서열 번호:10 내지 서열 번호:15, 서열 번호:28 내지 서열 번호:33, 서열 번호:30 내지 서열 번호:31, 서열 번호:42 내지 서열 번호:43, 서열 번호:38 내지 서열 번호:39, 서열 번호:50 내지 서열 번호:51, 서열 번호:168 내지 서열 번호:203 내의 동일한 위치의 분석을 위해 존재한다.
상기 올리고뉴클레오타이드는 또한 펩타이드 핵산의 형태로도 존재할 수 있다. 이어, 하이브리드 형성되지 않은 증폭물을 제거한다. 이어, 하이브리드 형성된 증폭물을 검출한다. 이와 관련하여, 증폭물에 부착된 라벨이 올리고뉴클레오타이드 서열이 위치하는 고상의 각 위치에서 확인가능한 것이 바람직하다.
본 방법의 또 다른 실시양태에서는, PCR 증폭 프라이머(이 때, 상기 프라이머는 메틸화 특이적이거나 표준일 수 있음)와 동시에 바이설파이트 처리된 DNA와 하이브리드 형성하는 올리고뉴클레오타이드 프로브(상기 상세히 기재된 바와 같음)에 의해 CpG 위치의 게놈 메틸화 현황을 확인할 수 있다.
이 방법의 특히 바람직한 실시양태는 이중-라벨링된 형광 올리고뉴클레오타이드 프로브를 사용하는 형광에 기초한 실시간 정량적 PCR[하이드(Heid) 등, Genome Res . 6:986-994, 1996; 또한 미국 특허 제 6,331,393 호 참조][ABI 프리즘 7700 서열 검출 시스템을 이용하는 택맨(TaqMan™) PCR, 퍼킨 엘머 어플라이드 바이오시스템즈(Perkin Elmer Applied Biosystems), 캘리포니아주 포스터 씨티]의 사용이다. 택맨(TaqMan™) PCR 반응은 바람직한 실시양태에서 전진 증폭 프라이머와 후진 증폭 프라이머 사이에 위치하는 CpG가 풍부한 서열과 하이브리드 형성하도록 디자인되는 택맨(TaqMan™) 프로브로 불리는 연장 불가능한 삽입 올리고뉴클레오타이드의 사용을 이용한다. 택맨(TaqMan™) 프로브는 택맨(TaqMan™) 올리고뉴클레오타이드의 뉴클레오타이드에 부착된 연결자 잔기(예컨대, 포스포르아미다이트)에 공유 결합된 형광 "리포터 잔기" 및 "켄처 잔기"를 추가로 포함한다. 바이설파이트 처리 후 핵산 내의 메틸화를 분석하기 위해서는, 메틸라이트(MethyLight™) 분석법으로도 알려져 있는 미국 특허 제 6,331,393 호(본원에 참고로 인용됨)에 기재된 바와 같이 프로브가 메틸화 특이적이어야 한다. 기재된 본 발명에 사용하기 적합한 택맨(TaqMan™) 검출 방법의 변형은 이중-프로브 기법[라이트사이클러(Lightcycler™)] 또는 형광 증폭 프라이머[선라이즈(Sunrise™) 기법]의 사용을 포함한다. 이들 두 기법은 모두 바이설파이트 처리된 DNA와 함께 사용하기에, 또한 CpG 다이뉴클레오타이드 내에서의 메틸화 분석에 적합한 방식으로 적합화될 수 있다.
본 발명의 추가로 바람직한 실시양태에서, 본 방법의 네번째 단계는 곤잘고 및 존스의 문헌[Nucleic Acids Res., 25:2529-2531, 1997]에 기재된 MS-SNuPE 같은 주형-유도되는 올리고뉴클레오타이드 연장의 이용을 포함한다.
본 방법의 또 다른 실시양태에서는, 본 방법의 네번째 단계가 본 방법의 세번째 단계에서 생성된 증폭물의 서열 결정 및 후속 서열 분석을 포함한다[상거(Sanger F.) 등, Proc Natl Acad Sci USA 74:5463-5467, 1977].
최선의 방식
본 발명의 가장 바람직한 실시양태에서는, 상기 개략적으로 기재된 처음 3가지 단계, 즉 a) 환자로부터 해당 게놈 DNA를 갖는 생물학적 샘플을 수득하는 단계; b) 게놈 DNA를 추출하거나 다른 방법으로 단리하는 단계; c) 5-위치에서 메틸화되지 않은 시토신 염기를 우라실 또는 하이브리드 형성 특성 면에서 시토신과 검출가능하게 상이한 다른 염기로 전환시키는 하나 이상의 시약으로 b)의 게놈 DNA 또는 그의 단편을 처리하는 단계에 따라 게놈 핵산을 단리 및 처리하고, 이 때 d) 메틸화 특이적인 방식으로, 즉 메틸화 특이적인 프라이머 또는 차단 올리고뉴클레오타이드를 사용함으로써 c)의 처리 후 증폭을 수행하고, e) 상기 기재된 바와 같이 실시간 검출 프로브에 의해 증폭물의 검출을 수행한다. 바람직하게는, 상기 기재된 바와 같이 메틸화 특이적 프라이머에 의해 d)의 후속 증폭을 수행하는 경우, 상기 메틸화 특이적 프라이머는 서열 번호:10 내지 서열 번호:15, 서열 번호:28 내지 서열 번호:33, 서열 번호:30 내지 서열 번호:31, 서열 번호:42 내지 서열 번호:43, 서열 번호:38 내지 서열 번호:39, 서열 번호:50 내지 서열 번호:51, 서열 번호:168 내지 서열 번호:203 및 이들에 상보적인 서열중 하나에 따른 처리된 핵산 서열과 하이브리드 형성하는 뉴클레오타이드 9개 이상의 길이를 갖는 서열을 포함한다.
방법의 단계 e), 즉 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167을 포함하는 군의 하나 이상의 서열의 하나 이상의 CpG 위치의 메틸화 현황을 나타내는 특정 증폭물의 검출은 상기 기재된 바와 같이 실시간 검출 방법에 의해 수행한다.
본 발명의 추가적인 실시양태는 바이설파이트 전환을 필요로 하지 않으면서 본 발명에 따른 게놈 DNA(서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167, 및 이들의 보체)의 메틸화 현황을 분석하는 방법을 제공한다. 표적 영역 내의 메틸화된 CpG 다이뉴클레오타이드 및 메틸화되지 않은 CpG 다이뉴클레오타이드를 구분하는 메틸화 민감성 제한 효소 시약 또는 메틸화 민감성 제한 효소 시약을 포함하는 일련의 제한 효소 시약을 메틸화(예컨대, DMH, 이로 한정되지는 않음)를 결정하는데 사용하는 방법은 당해 분야에 공지되어 있다.
이러한 추가적인 실시양태의 첫번째 단계에서는, 조직 또는 세포 공급원으로부터 게놈 DNA 샘플을 단리한다. 시판중인 키트의 사용을 비롯한 당해 분야에서 표준인 임의의 수단에 의해 게놈 DNA를 단리할 수 있다. 간략히, 관심 있는 DNA가 세포막에 의해 캡슐화되는 경우, 생물학적 샘플을 효소적, 화학적 또는 기계적 수단에 의해 파괴 및 용해시켜야 한다. 이어, DNA 용액을 예컨대 프로테이나제 K로 소화시킴으로써 단백질 및 다른 오염물질을 제거할 수 있다. 이어, 게놈 DNA를 용액으로부터 회수한다. 염석, 유기 추출 또는 DNA의 고상 지지체로의 결합을 비롯한 다양한 수단에 의해 이를 수행할 수 있다. 방법의 선택은 시간, 비용 및 요구되는 DNA의 양을 포함한 수 가지 인자에 의해 영향을 받는다. 종양성 또는 잠재적으로 종양성인 물질을 포함하는 모든 임상 샘플 유형이 본 방법에 사용하기 적합하며, 세포주, 조직학적 슬라이드, 생검체, 파라핀-매립된 조직, 신체 유체, 대변, 결장 유출물, 소변, 혈장, 혈청, 전혈, 단리된 혈액 세포, 혈액으로부터 단리된 세포 및 이들의 조합이 바람직하다. 신체 유체가 DNA의 바람직한 공급원이며, 혈장, 혈청, 전혈, 단리된 혈액 세포 및 혈액으로부터 단리된 세포가 특히 바람직하다.
핵산을 추출한 후에는, 게놈 이중-가닥 DNA를 분석에 사용한다.
바람직한 실시양태에서는, 메틸화 민감성 제한 효소로 DNA를 처리 전에 절단할 수 있다. 이러한 방법은 당해 분야에 공지되어 있고, 물리적 수단 및 효소적 수단을 둘 다 포함할 수 있다. 특히 바람직한 것은 메틸화 민감성이지 않고 그의 인식 부위에서 AT가 풍부하며 CG 다이뉴클레오타이드를 포함하지 않는 하나 또는 복수개의 제한 효소를 사용하는 것이다. 이러한 효소의 사용으로 인해, 단편화된 DNA에서 CpG 섬 및 CpG가 풍부한 영역이 보존될 수 있다. 비-메틸화-특이적 제한 효소는 MseI, BfaI, Csp6I, Tru1I, Tvu1I, Tru9I, Tvu9I, MaeI 및 XspI로 이루어진 군으로부터 바람직하게 선택된다. 특히 바람직한 것은 이들 효소중 둘 또는 셋을 사용하는 것이다. MseI, BfaI 및 Csp6I의 조합을 사용하는 것이 특히 바람직하다.
후속 효소적 증폭을 용이하게 하기 위하여, 단편화된 DNA를 어댑터 올리고뉴클레오타이드에 연결할 수 있다. 둔단 및 점착단 DNA 단편으로의 올리고뉴클레오타이드의 연결은 당해 분야에 공지되어 있고, 말단의 탈포스포릴화(예컨대, 송아지 또는 새우 알칼리성 포스파타제를 사용하여) 및 dATP의 존재하에서 리가제 효소(예컨대, T4 DNA 리가제)를 사용하는 후속 연결에 의해 수행한다. 어댑터 올리고뉴클레오타이드는 전형적으로 염기 쌍 18개 이상의 길이이다.
세번째 단계에서는, 하나 이상의 메틸화 민감성 제한 효소로 DNA(또는 그의 단편)를 소화시킨다. 제한 부위에서의 DNA의 가수분해가 셉틴 9(그의 모든 전사 변이형 포함), FOXL2, SARM1, VTN, PRDM6, NR2E1, FAT 및 서열 번호:160 내지 서열 번호:165로 이루어진 군으로부터 선택되는 하나 이상의 유전자 또는 게놈 서열의 특이적인 CpG 다이뉴클레오타이드의 메틸화 현황에 대한 정보를 주도록 하는 방식으로 소화를 수행한다.
바람직하게는, 메틸화-특이적 제한 효소는 Bsi E1 , Hga I HinPI , Hpy99I , Ava I, Bce AI , Bsa HI , BisI , BstUI , BshI236I , AccII , BstFNI , McrBC , GlaI , MvnI, HpaII ( HapII ), HhaI , AciI , SmaI , HinP1I , HpyCH4IV , EagI 및 상기 효소중 둘 이상의 혼합물로 이루어진 군으로부터 선택된다. 바람직한 것은 제한 효소 BstUI, HpaII, HpyCH4IV 및 HinP1I를 함유하는 혼합물이다.
임의적이지만 바람직한 실시양태인 네번째 단계에서는, 제한 단편을 증폭시킨다. 폴리머라제 연쇄 반응을 이용하여 이를 바람직하게 수행하며, 상기 증폭물은 상기 논의된 바와 같이 적합한 검출가능한 라벨, 즉 형광체 파벨, 방사성 핵종 및 질량 라벨을 가질 수 있다. 증폭 효소 및 각각의 경우 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167 및 이들의 보체로 이루어진 군으로부터 선택되는 서열에 상보적이거나 또는 적당히 엄격하거나 엄격한 조건하에 상기 서열과 하이브리드 형성하는 뉴클레오타이드 16개 이상의 길이를 갖는 연속적인 서열을 포함하는 둘 이상의 프라이머에 의해 증폭시키는 것이 특히 바람직하다. 바람직하게는, 상기 연속적인 서열은 뉴클레오타이드 16개 이상, 20개 이상 또는 25개 이상의 길이를 갖는다. 다른 실시양태에서, 상기 프라이머는 단편에 연결된 임의의 어댑터에 상보적일 수 있다.
다섯번째 단계에서는, 증폭물을 검출한다. 당해 분야에서 표준인 임의의 수단, 예를 들어 겔 전기영동 분석, 하이브리드 형성 분석, PCR 생성물 내의 검출가능한 택의 혼입, DNA 어레이 분석, MALDI 또는 ESI 분석(이들로 한정되지는 않음)에 의해 검출할 수 있다. 바람직하게는, 각각의 경우 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167 및 이들의 보체로 이루어진 군으로부터 선택되는 서열에 상보적이거나 또는 적당히 엄격하거나 엄격한 조건하에서 상기 서열과 하이브리드 형성하는 뉴클레오타이드 16개 이상의 길이를 갖는 연속적인 서열을 포함하는 하나 이상의 핵산 또는 펩타이드 핵산과 하이브리드를 형성함으로써, 상기 검출을 수행한다. 바람직하게는, 상기 연속적인 서열은 뉴클레오타이드 16개 이상, 20개 이상 또는 25개 이상의 길이를 갖는다.
게놈 핵산의 메틸화 상태 또는 수준을 결정한 후에는, 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167로 이루어진 군으로부터 선택되는 하나 이상의 서열의 하나 이상의 CpG 다이뉴클레오타이드 서열의 메틸화 상태 또는 수준, 또는 평균 또는 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167로 이루어진 군으로부터 선택되는 하나 이상의 서열의 복수개의 CpG 다이뉴클레오타이드 서열의 평균 메틸화 상태를 반영하는 값에 기초하여 세포 증식 질환의 존재, 부재 또는 부류를 유추하며, 이 때 상기 메틸화는 종양성 또는 종양전 세포 증식 질환과 관련되어 있다. 상기 메틸화를 정량적 수단에 의해 결정하는 경우, 상기 메틸화의 존재를 결정하기 위한 컷-오프 점은 바람직하게는 0이다. 즉, 샘플이 임의의 메틸화 정도를 나타내는 경우, 이는 분석된 CpG 위치에서 메틸화된 상태를 갖는 것으로 결정된다. 그럼에도 불구하고, 당해 분야의 숙련자는 특히 바람직한 민감도 또는 특이성의 분석법을 제공하기 위하여, 상기 컷-오프 값을 조정하고자 할 수 있는 것으로 예견된다. 따라서, 상기 컷-오프 값을 높일 수 있고(따라서, 특이성을 높임), 상기 컷-오프 값은 0% 내지 5%, 5% 내지 10%, 10% 내지 15%, 15% 내지 20%, 20% 내지 30% 및 30% 내지 50%로 이루어진 군으로부터 선택되는 범위 내에 속할 수 있다. 특히 바람직한 것은 컷-오프 10%, 15%, 25% 및 30%이다.
유전자 패널이 셉틴 9 또는 그의 절단된 전사물 Q9HC74 및 FOXL2, NGFR, TMEFF2, SIX6, SARM1, VTN 및 ZDHHC22로 이루어진 군으로부터 선택되는 하나 이상의 유전자를 포함하는 다른 실시양태에서는, 게놈 핵산의 메틸화 상태를 결정한 후, 서열 번호:1의 하나 이상의 CpG 다이뉴클레오타이드 서열 및 서열 번호:24 내지 서열 번호:29의 하나 이상의 CpG 다이뉴클레오타이드 서열의 메틸화 상태, 또는 평균 또는 복수개의 CpG 다이뉴클레오타이드 서열의 평균 메틸화 상태를 반영하는 값에 기초하여 세포 증식 질환, 구체적으로는 간 및/또는 직장결장 세포 증식 질환의 존재, 부재 또는 아부류를 유추하며, 이 때 과메틸화는 암, 구체적으로는 간암 및/또는 직장결장암과 관련이 있다.
세포 증식 질환의 진단 및 예후 판정 분석법
본 발명은 셉틴 9(그의 모든 전사 변이형 포함), FOXL2, SARM1, VTN, PRDM6, NR2E1, FAT 및 서열 번호:160 내지 서열 번호:165로 이루어진 군으로부터 선택되는 하나 이상의 유전자 또는 게놈 서열 내의 중요한 유전학적 및/또는 후성학적 매개변수를 마커로서 사용할 수 있는, 환자 또는 개체에 불리한 사건의 진단을 가능케 한다. 본 발명의 수단에 의해 수득되는 상기 매개변수를 유전학적 및/또는 후성학적 매개변수의 다른 세트와 비교할 수 있으며, 그 차이는 환자 또는 개체에게 불리한 사건의 진단 및/또는 예후 판정의 기초로서 작용한다.
더욱 구체적으로, 본 발명은 암, 가장 바람직하게는 간암 및/또는 직장결장 암종의 초기 검출을 위한 위험한 개체군의 스크리닝을 가능케 한다. 뿐만 아니라, 본 발명은 종양성(예컨대, 악성) 세포 증식 질환을 양성(즉, 비-암성) 세포 증식 질환으로부터 구별할 수 있게 한다. 예를 들어, 본 발명은 직장결장 암종을 작은 결장 암종 또는 폴립으로부터 구별할 수 있게 한다. 종양성 세포 증식 질환은 상기 양성 질환과는 대조적으로 셉틴 9(그의 모든 전사 변이형 포함), FOXL2, SARM1, VTN, PRDM6, NR2E1, FAT 및 서열 번호:160 내지 서열 번호:165로 이루어진 군으로부터 선택되는 하나 이상의 유전자 또는 게놈 서열 내에서 감소된 메틸화(즉, 감소된 발현)를 나타낸다.
구체적으로, 본 발명은 CpG 다이뉴클레오타이드 서열을 포함하는 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167로 이루어진 군으로부터 선택되는 하나 이상의 서열의 하나 이상의 CpG 다이뉴클레오타이드 서열의 차별적인 발현(바람직하게는 메틸화)의 측정에 기초한 진단 및 분류용 암 분석법을 제공한다. 전형적으로, 이러한 분석법은 환자로부터 샘플을 수득하고, 바람직하게는 샘플로부터 유도되는 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167로 이루어진 군으로부터 선택되는 하나 이상의 서열의 메틸화 현황을 대조용 샘플 또는 공지의 기준과 비교하여 결정함으로써, 셉틴 9(그의 모든 전사 변이형 포함), FOXL2, SARM1, VTN, PRDM6, NR2E1, FAT 및 서열 번호:160 내지 서열 번호:165로 이루어진 군으로부터 선택되는 하나 이상의 유전자 또는 게놈 서열의 발현을 측정하는 분석법을 수행하고, 그에 기초하여 진단함을 포함한다.
특히 바람직한 실시양태에서는, 본 발명의 올리고머를, 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167, 서열 번호:10 내지 서열 번호:15, 서열 번호:28 내지 서열 번호:33, 서열 번호:30 내지 서열 번호:31, 서열 번호:42 내지 서열 번호:43, 서열 번호:38 내지 서열 번호:39, 서열 번호:50 내지 서열 번호:51, 서열 번호:168 내지 서열 번호:203 또는 이들의 어레이에 기초한 것과 같은 CpG 다이뉴클레오타이드 메틸화 현황을 사정하는데, 또한 그에 기초하고 세포 증식 질환의 진단 및/또는 분류에 유용한 키트에 사용한다.
키트
뿐만 아니라, 본 발명의 추가의 요지는 셉틴 9(그의 모든 전사 변이형 포함), FOXL2, SARM1, VTN, PRDM6, NR2E1, FAT 및 서열 번호:160 내지 서열 번호:165로 이루어진 군으로부터 선택되는 하나 이상의 유전자 또는 게놈 서열의 메틸화를 결정하는 수단을 포함하는 키트이다. 메틸화를 결정하는 수단은 바람직하게는 바이설파이트-함유 시약; 각각의 경우 그의 서열이 서열 번호:10 내지 서열 번호:15, 서열 번호:28 내지 서열 번호:33, 서열 번호:30 내지 서열 번호:31, 서열 번호:42 내지 서열 번호:43, 서열 번호:38 내지 서열 번호:39, 서열 번호:50 내지 서열 번호:51, 서열 번호:168 내지 서열 번호:203으로부터 선택되는 서열의 염기 9개 이상, 바람직하게는 18개의 길이의 구획과 동일하거나, 상보적이거나, 또는 엄격하거나 매우 엄격한 조건하에서 상기 구획과 하이브리드 형성하는 하나 또는 복수개의 올리고뉴클레오타이드; 및 임의적으로는 기재된 메틸화 분석 방법을 수행 및 평가하기 위한 설명서를 포함한다. 한 실시양태에서, 상기 올리고뉴클레오타이드의 염기 서열은 하나 이상의 CpG, CpA 또는 TpG 다이뉴클레오타이드를 포함한다.
추가의 실시양태에서, 상기 키트는 CpG 위치-특이적 메틸화 분석을 수행하기 위한 표준 시약을 추가로 포함할 수 있으며, 이 때 상기 분석은 하기 기법중 하나 이상을 포함한다: MS-SNuPE, MSP, 메틸라이트(MethyLight™), 헤비메틸, COBRA, 및 핵산 서열 결정. 그러나, 본 발명에 따른 키트는 또한 전술한 성분중 일부만을 함유할 수도 있다.
바람직한 실시양태에서, 키트는 DNA 변성 완충액; 설폰화 완충액; DNA 회수 시약 또는 키트(예컨대, 침전, 한외여과, 친화력 칼럼); 탈설폰화 완충액; 및 DNA 회수 성분으로 이루어진 군으로부터 선택되는 추가적인 바이설파이트 전환 시약을 포함할 수 있다.
추가의 다른 실시양태에서, 키트는 폴리머라제 및 폴리머라제에 의해 매개되는 프라이머 연장(예: PCR)에 대해 최적화된 반응 완충액을 별도의 용기에 포장하여 함유할 수 있다. 본 발명의 다른 실시양태에서, 키트는 환자의 생물학적 샘플을 함유하는 수단을 추가로 포함한다. 바람직한 것은, 환자의 생물학적 샘플중의 셉틴 9(그의 모든 전사 변이형 포함), FOXL2, SARM1, VTN, PRDM6, NR2E1, FAT 및 서열 번호:160 내지 서열 번호:165로 이루어진 군으로부터 선택되는 하나 이상의 유전자 또는 게놈 서열의 메틸화를 결정하기 위한 수단을 함유하는데 적합한 용기를 추가로 포함하는 키트이고, 가장 바람직하게는 키트 결과물을 사용 및 해석하기 위한 설명서를 추가로 포함하는 키트이다. 바람직한 실시양태에서, 키트는 (a) 바이설파이트 시약; (b) 상기 바이설파이트 시약 및 환자의 생물학적 샘플을 함유하는데 적합한 용기; (c) 각각의 경우 그의 서열이 서열 번호: 10 내지 서열 번호:15, 서열 번호:28 내지 서열 번호:33, 서열 번호:30 내지 서열 번호:31, 서열 번호:42 내지 서열 번호:43, 서열 번호:38 내지 서열 번호:39, 서열 번호:50 내지 서열 번호:51, 서열 번호:168 내지 서열 번호:203으로부터 선택되는 서열의 염기 9개 이상, 바람직하게는 18개의 길이를 갖는 구획과 동일하거나, 그에 상보적이거나, 또는 엄격하거나 매우 엄격한 조건하에서 상기 구획과 하이브리드 형성하는 2개의 올리고뉴클레오타이드를 함유하는 프라이머 올리고뉴클레오타이드의 하나 이상의 세트; 및 임의적으로 (d) 키트 결과물을 사용 및 해석하기 위한 설명서를 포함한다. 다른 바람직한 실시양태에서, 키트는 (a) 바이설파이트 시약; (b) 상기 바이설파이트 시약 및 환자의 생물학적 샘플을 수용하는데 적합한 용기; (c) 서열 번호:10 내지 서열 번호:15, 서열 번호:28 내지 서열 번호:33, 서열 번호:30 내지 서열 번호:31, 서열 번호:42 내지 서열 번호:43, 서열 번호:38 내지 서열 번호:39, 서열 번호:50 내지 서열 번호:51, 서열 번호:168 내지 서열 번호:203 및 이들에 상보적인 서열중 하나에 따른 미리-처리된 핵산 서열과 동일하거나 이들 서열과 하이브리드 형성하는 뉴클레오타이드 9개 이상 또는 16개 이상의 길이를 갖는 하나 이상의 올리고뉴클레오타이드 및/또는 PNA-올리고머; 및 임의적으로 (d) 키트 결과물을 사용 및 해석하기 위한 설명서를 포함한다.
다른 실시양태에서, 키트는 (a) 바이설파이트 시약; (b) 상기 바이설파이트 시약 및 환자의 생물학적 샘플을 함유하는데 적합한 용기; (c) 각각의 경우 그의 서열이 서열 번호:10 내지 서열 번호:15, 서열 번호:28 내지 서열 번호:33, 서열 번호:30 내지 서열 번호:31, 서열 번호:42 내지 서열 번호:43, 서열 번호:38 내지 서열 번호:39, 서열 번호:50 내지 서열 번호:51, 서열 번호:168 내지 서열 번호:203으로부터 선택되는 서열의 염기 9개 이상, 바람직하게는 18개의 길이를 갖는 구획과 동일하거나, 그에 상보적이거나, 또는 엄격하거나 고도로 엄격한 조건하에서 이들 구획과 하이브리드 형성하는 2개의 올리고뉴클레오타이드를 함유하는 프라이머 올리고뉴클레오타이드의 하나 이상의 세트; (d) 서열 번호:10 내지 서열 번호:15, 서열 번호:28 내지 서열 번호:33, 서열 번호:30 내지 서열 번호:31, 서열 번호:42 내지 서열 번호:43, 서열 번호:38 내지 서열 번호:39, 서열 번호:50 내지 서열 번호:51, 서열 번호:168 내지 서열 번호:203 및 이들에 상보적인 서열중 하나에 따른 미리-처리된 핵산 서열과 동일하거나 이들 서열과 하이브리드 형성하는 뉴클레오타이드 9개 이상 또는 16개 이상의 길이를 갖는 하나 이상의 올리고뉴클레오타이드 및/또는 PNA-올리고머; 및 임의적으로 (e) 키트 결과물의 사용 및 해석을 위한 설명서를 포함한다.
키트는 또한 별도의 용기에 포장된, 차단, 세척 또는 코팅에 적합한 완충액 또는 용액 같은 다른 성분도 함유할 수 있다.
COBRA™ 분석에 전형적인 시약(전형적인 COBRA™-계 키트에서 발견되는 바와 같음)은 셉틴 9(그의 모든 전사 변이형 포함), FOXL2, SARM1, VTN, PRDM6, NR2E1, FAT 및 서열 번호:160 내지 서열 번호:165로 이루어진 군으로부터 선택되는 하나 이상의 유전자 또는 게놈 서열의 PCR 프라이머; 제한 효소 및 적절한 완충액; 유전자-하이브리드 형성 올리고; 대조용 하이브리드 형성 올리고; 올리고 프로브용 키나제 라벨링 키트; 및 라벨링된 뉴클레오타이드를 포함할 수 있으나, 이들로 국한되지는 않는다. 메틸라이트(MethyLight™) 분석에 전형적인 시약(예컨대, 전형적인 메틸라이트(MethyLight™)-계 키트에서 발견되는 바와 같음)은 셉틴 9(그의 모든 전사 변이형 포함), FOXL2, SARM1, VTN, PRDM6, NR2E1, FAT 및 서열 번호:160 내지 서열 번호:165로 이루어진 군으로부터 선택되는 하나 이상의 유전자 또는 게놈 서열의 바이설파이트 전환된 서열용 PCR 프라이머; 바이설파이트 특이적 프로브[예를 들어, 택맨(TaqMan™) 또는 라이트사이클러(Lightcycler™)]; 최적화된 PCR 완충액 및 데옥시뉴클레오타이드; 및 Taq 폴리머라제를 포함할 수 있지만, 이들로 한정되는 않는다.
Ms-SNuPE™ 분석에 전형적인 시약(예를 들어, 전형적인 Ms-SNuPE™-계 키트에서 발견되는 바와 같음)은 특이적인 유전자(또는 바이설파이트 처리된 DNA 서열 또는 CpG 섬)용 PCR 프라이머; 최적화된 PCR 완충액 및 데옥시뉴클레오타이드; 겔 추출 키트; 양성 대조용 프라이머; 셉틴 9(그의 모든 전사 변이형 포함), FOXL2, SARM1, VTN, PRDM6, NR2E1, FAT 및 서열 번호:160 내지 서열 번호:165로 이루어진 군으로부터 선택되는 하나 이상의 유전자 또는 게놈 서열의 바이설파이트 전환된 서열용 Ms-SNuPE™ 프라이머; 반응 완충액(Ms-SNuPE 반응용); 및 라벨링된 뉴클레오타이드를 포함할 수 있으나, 이들로 한정되지는 않는다.
MSP 분석에 전형적인 시약(예컨대, 전형적인 MSP-계 키트에서 발견되는 것과 같음)은 셉틴 9(그의 모든 전사 변이형 포함), FOXL2, SARM1, VTN, PRDM6, NR2E1, FAT 및 서열 번호:160 내지 서열 번호:165로 이루어진 군으로부터 선택되는 유전자 또는 게놈 서열의 바이설파이트 전환된 서열용의 메틸화된 PCR 프라이머 및 메틸화되지 않은 PCR 프라이머; 최적화된 PCR 완충액; 데옥시뉴클레오타이드; 및 특이적인 프로브를 포함할 수 있으나, 이들로 한정되는 것은 아니다.
뿐만 아니라, 본 발명의 추가적인 요지는 셉틴 9(그의 모든 전사 변이형 포함), FOXL2, SARM1, VTN, PRDM6, NR2E1, FAT 및 서열 번호:160 내지 서열 번호:165로 이루어진 군으로부터 선택되는 하나 이상의 유전자 또는 게놈 서열의 메틸화를 결정하기 위한 수단(이 때, 상기 수단은 바람직하게는 하나 이상의 메틸화 특이적 제한 효소를 포함함); 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167로부터 선택되는 서열의 하나 이상의 CpG 다이뉴클레오타이드를 포함하는 서열의 증폭에 적합한 하나 또는 복수개의 프라이머 올리고뉴클레오타이드(바람직하게는 하나 또는 복수개의 프라이머 쌍); 및 임의적으로는 기재된 메틸화 분석 방법을 수행 및 사정하기 위한 설명서를 포함하는 다른 키트이다. 한 실시양태에서, 상기 올리고뉴클레오타이드의 염기 서열은 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167로부터 선택되는 서열의 염기 18개 이상의 길이를 갖는 구획과 동일하거나, 상보적이거나, 또는 엄격하거나 매우 엄격한 조건하에서 상기 구획과 하이브리드 형성한다.
추가적인 실시양태에서, 상기 키트는 소화 단편을 분석하기 위한 하나 또는 복수개의 올리고뉴클레오타이드 프로브를 포함할 수 있으며, 바람직하게는 상기 올리고뉴클레오타이드는 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167로부터 선택되는 서열의 염기 16개 이상의 길이를 갖는 구획과 동일하거나, 그에 상보적이거나, 또는 엄격하거나 매우 엄격한 조건하에서 상기 구획과 하이브리드 형성한다.
바람직한 실시양태에서, 키트는 완충액(예컨대, 제한 효소, PCR, 저장 또는 세척 완충액); DNA 회수 시약 또는 키트(예컨대, 침전, 한외여과, 친화력 칼럼) 및 DNA 회수 성분으로 이루어진 군으로부터 선택되는 추가의 시약을 포함할 수 있다.
추가의 다른 실시양태에서, 키트는 폴리머라제 및 폴리머라제에 의해 매개되는 프라이머 연장(예: PCR)에 대해 최적화된 반응 완충액을 별도의 용기에 포장하여 함유할 수 있다. 본 발명의 다른 실시양태에서, 키트는 환자의 생물학적 샘플을 수득하는 수단을 추가로 포함한다. 바람직한 실시양태에서, 키트는 (a) 메틸화 민감성 제한 효소 시약; (b) 상기 시약 및 환자의 생물학적 샘플을 함유하는데 적합한 용기; (c) 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167로부터 선택되는 염기 9개 이상의 길이를 갖는 구획과 동일하거나, 그에 상보적이거나, 또는 엄격하거나 매우 엄격한 조건하에서 상기 구획과 하이브리드 형성하는 하나 또는 복수개의 핵산 또는 펩타이드 핵산의 하나 이상의 올리고뉴클레오타이드 세트; 및 임의적으로는 (d) 키트 결과물을 사용 및 해석하기 위한 설명서를 포함한다.
다른 바람직한 실시양태에서, 키트는 (a) 메틸화 민감성 제한 효소 시약; (b) 상기 시약 및 환자의 생물학적 샘플을 함유하는데 적합한 용기; (c) 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167로부터 선택되는 서열의 하나 이상의 CpG 다이뉴클레오타이드를 포함하는 서열의 증폭에 적합한 하나 이상의 프라이머 올리고뉴클레오타이드 세트; 및 임의적으로는 (d) 키트 결과물을 사용 및 해석하기 위한 설명서를 포함한다.
다른 실시양태에서, 키트는 (a) 메틸화 민감성 제한 효소 시약; (b) 상기 시약 및 환자의 생물학적 샘플을 함유하는데 적합한 용기; (c) 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167로부터 선택되는 서열의 하나 이상의 CpG 다이뉴클레오타이드를 포함하는 서열의 증폭에 적합한 프라이머 올리고뉴클레오타이드의 하나 이상의 세트; (d) 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167로부터 선택되는 서열의 염기 9개 이상의 길이를 갖는 구획과 동일하거나, 그에 상보적이거나, 또는 엄격하거나 매우 엄격한 조건하에서 이들 구획과 하이브리드 형성하는 하나 또는 복수개의 핵산 또는 펩타이드 핵산의 하나 이상의 올리고뉴클레오타이드 세트; 및 임의적으로는 (e) 키트 결과물을 사용 및 해석하기 위한 설명서를 포함한다.
키트는 또한 별도의 용기에 포장된, 차단, 세척 또는 코팅에 적합한 완충액 또는 용액 같은 다른 성분도 함유할 수 있다.
본 발명은 또한 메틸화-민감성 제한 효소 분석에 의해 환자에서 세포 증식 질환의 존재를 진단하는데 사용하기 위한 키트에 관한 것이다. 상기 키트는 용기 및 DNA 마이크로어레이 성분을 포함한다. 상기 DNA 마이크로어레이 성분은 복수개의 올리고뉴클레오타이드가 지정된 위치에 부동화된 표면이며, 올리고뉴클레오타이드는 하나 이상의 CpG 메틸화 부위를 포함한다. 상기 올리고뉴클레오타이드중 하나 이상은 셉틴 9(그의 모든 전사 변이형 포함), FOXL2, SARM1, VTN, PRDM6, NR2E1, FAT 및 서열 번호:160 내지 서열 번호:165로 이루어진 군으로부터 선택되는 하나 이상의 유전자 또는 게놈 서열에 특이적이고, 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167중 하나에 따른 서열의 염기 15개 이상의 길이(그러나, 200bp 이하)를 갖는 서열을 포함한다. 바람직하게는, 상기 서열은 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167중 하나에 따른 서열의 염기 쌍 15개 이상의 길이(그러나, 80bp 이하)를 갖는 서열을 포함한다. 상기 서열이 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167중 하나에 따른 서열의 염기 쌍 20개 이상의 길이(그러나, 30bp 이하)를 갖는 것이 또한 바람직하다.
상기 시험 키트는 바람직하게는 하나 또는 복수개의 메틸화-민감성 제한 효소를 포함하는 제한 효소 성분을 추가로 포함한다.
추가의 실시양태에서, 상기 시험 키트는 하나 이상의 메틸화-특이적 제한 효소를 포함하고 상기 올리고뉴클레오타이드가 상기 하나 이상의 메틸화 특이적 제한 효소의 제한 부위를 포함함을 또한 특징으로 한다.
키트는 DNA를 풍부하게 하기 위해 당해 분야에 공지된 하기 성분중 하나 또는 수 가지를 추가로 포함할 수 있다: 메틸화된 DNA에 선택적으로 결합하는 단백질 성분; 임의적으로는 적합한 용액중의 삼중 가닥-형성 핵산 성분, 하나 또는 복수개의 연결자; 연결을 수행하기 위한 성분 또는 용액, 예컨대 리가제, 완충액; 칼럼 크로마토그래피를 수행하기 위한 성분 또는 용액; 면역학에 기초하여 풍부하게 만들기(예컨대, 면역 침전) 위한 성분 또는 용액; 핵산 증폭, 예컨대 PCR을 수행하기 위한 성분 또는 용액; 적용가능한 경우 커플링 시약과 함께, 적용가능한 경우 용액중의 염료 또는 수 가지 염료; 하이브리드 형성을 수행하기 위한 성분 또는 용액; 및/또는 세척 단계를 수행하기 위한 성분 또는 용액.
기재된 발명은 결장 세포 증식 질환을 검출, 구별 및 구분하는데 유용한 물질의 조성물을 추가로 제공한다. 상기 조성물은 서열 번호:10 내지 서열 번호:15, 서열 번호:28 내지 서열 번호:33, 서열 번호:30 내지 서열 번호:31, 서열 번호:42 내지 서열 번호:43, 서열 번호:38 내지 서열 번호:39, 서열 번호:50 내지 서열 번호:51, 서열 번호:168 내지 서열 번호:203에 개시된 핵산 서열의 염기 쌍 18개의 길이를 갖는 구획의 하나 이상의 핵산, 및 1 내지 5mM 염화마그네슘, 100 내지 500μM dNTP, 0.5 내지 5단위 taq 폴리머라제, 소 혈청 알부민; 각각의 경우 서열 번호:10 내지 서열 번호:15, 서열 번호:28 내지 서열 번호:33, 서열 번호:30 내지 서열 번호:31, 서열 번호:42 내지 서열 번호:43, 서열 번호:38 내지 서열 번호:39, 서열 번호:50 내지 서열 번호:51, 서열 번호:168 내지 서열 번호:203 및 이들에 상보적인 서열에 대해 상보적이거나, 또는 적당히 엄격하거나 엄격한 조건하에서 이들 서열과 하이브리드 형성하는 뉴클레오타이드 9개 이상의 길이를 갖는 하나 이상의 염기 서열을 포함하는 올리고머, 특히 올리고뉴클레오타이드 또는 펩타이드 핵산(PNA)-올리고머를 포함한다. 상기 물질의 조성물이 수용액 중에서 상기 핵산을 안정화시키고 상기 용액 내에서 폴리머라제에 기초한 반응을 가능케 하는데 적절한 완충 용액을 포함하는 것이 바람직하다. 적합한 완충액은 당해 분야에 공지되어 있고 시판되고 있다.
본 발명의 추가의 바람직한 실시양태에서, 상기 하나 이상의 핵산은 서열 번호:10 내지 서열 번호:15, 서열 번호:28 내지 서열 번호:33, 서열 번호:30 내지 서열 번호:31, 서열 번호:42 내지 서열 번호:43, 서열 번호:38 내지 서열 번호:39, 서열 번호:50 내지 서열 번호:51, 서열 번호:168 내지 서열 번호:203에 개시된 핵산 서열의 염기 쌍 50개 이상, 100개 이상, 150개 이상, 200개 이상, 250개 이상 또는 500개 이상의 길이를 갖는 구획이다.
본 발명을 그의 바람직한 특정 실시양태에 따라 구체적으로 기재하였으나, 하기 실시예는 본 발명을 예시하는 역할만을 하고, 본 발명의 가장 넓게 해석된 형태 및 그의 등가 구성의 영역 및 원리 내에서 본 발명을 한정하고자 하지 않는다.
실시예 1
하기 실시예에서는, MSP 및/또는 헤비메틸 분석법에 의해 아래 나열된 서열을 분석하였다. 분석법은 라이트사이클러 플랫폼[롯슈 다이아그노스틱스(Roche Diagnostics)]에서 수행되도록 디자인되지만, 당해 분야에서 통상적으로 사용되는 이러한 다른 기구도 적합하다.
택맨 스타일 형광 라벨링된 검출 프로브에 의해 MSP 증폭물을 검출하고, 라 이트사이클러 스타일 이중 프로브에 의해 헤비메틸 증폭물을 검출한다.
관심 있는 게놈 영역:
서열 번호:165
분석법 유형: 헤비메틸
프라이머:
서열 번호:249
서열 번호:250
차단체:
서열 번호:251
프로브:
서열 번호:252
서열 번호:253
온도 사이클링 프로그램:
활성화: 95℃ 10분
55회 사이클: 95℃ 10초(20℃/초); 56℃ 30초(20℃/초); 72℃ 10초(20℃/초)
용융
95℃ 10초 20; 35℃ 20초 20 검출; 95℃ 0초 0.1
관심 있는 게놈 영역:
서열 번호:24
분석법 유형: 헤비메틸
프라이머:
서열 번호:254
서열 번호:155
차단체:
서열 번호:256
프로브:
서열 번호:257(형광 라벨링)
서열 번호:258(Red640 라벨링)
온도 사이클링 프로그램:
95℃에서의 변성
95℃ 10분
55회 사이클:
변성 95℃ 10초(20℃/초)
어닐링 56℃ 30초(20℃/초)
연장 72℃ 10초(20℃/초)
용융
95℃ 10초 20; 35℃ 20초 20; 95℃ 0초 0.1
관심 있는 게놈 영역:
서열 번호:24
분석법 유형: 헤비메틸
프라이머:
서열 번호:264
서열 번호:265
차단체:
서열 번호:266
프로브:
서열 번호:267(형광 라벨링됨)
서열 번호:268(Red640 라벨링됨)
온도 사이클링 프로그램:
95℃에서의 변성
95℃ 10분
55회 사이클:
변성 95℃ 10초(20℃/초)
어닐링 56℃ 30초(20℃/초)
연장 72℃ 10초(20℃/초)
용융
95℃ 10초 20; 35℃ 20초 20; 95℃ 0초 0.1
관심 있는 게놈 영역:
서열 번호:28
분석법 유형: MSP
프라이머:
서열 번호:274
서열 번호:275
택맨 프로브:
서열 번호:276
온도 사이클링 프로그램:
활성화: 95℃ 10분
55회 사이클: 95℃ 15초(20℃/초); 62℃ 45초(20℃/초)
냉각: 40℃ 5초
관심 있는 게놈 영역:
서열 번호:1
분석법 유형: MSP
프라이머:
서열 번호:277
서열 번호:278
택맨 프로브:
서열 번호:279
온도 사이클링 프로그램:
활성화: 95℃ 10분
55회 사이클: 95℃ 15초(20℃/초); 62℃ 45초(20℃/초)
냉각: 40℃ 5초
관심 있는 게놈 영역:
서열 번호:28
분석법 유형: MSP
프라이머:
서열 번호:280
서열 번호:281
택맨 프로브:
서열 번호:282
온도 사이클링 프로파일:
활성화: 95℃ 10분
55회 사이클: 95℃ 15초(20℃/초); 62℃ 45초(20℃/초)
관심 있는 게놈 영역:
서열 번호:1
분석법 유형: MSP
프라이머:
서열 번호:283
서열 번호:284
택맨 프로브:
서열 번호:285
온도 사이클링 프로파일:
활성화: 95℃ 10분
55회 사이클: 95℃ 15초(20℃/초); 62℃ 45초(20℃/초)
관심 있는 게놈 영역:
서열 번호:28
분석법 유형: 헤비메틸
프라이머:
서열 번호:286
서열 번호:287
차단체:
서열 번호:288
프로브:
서열 번호:289
서열 번호:290
온도 사이클링 프로파일:
95℃에서의 활성화
95℃ 10분
50회 사이클
변성 95℃ 10초(20℃/초)
어닐링 56℃ 30초(20℃/초)
연장 72℃ 10초(20℃/초)
용융
95℃ 10초 20
40℃ 10초 20
70℃ 0초 0.1
냉각
40℃ 5초
관심 있는 게놈 영역:
서열 번호:1
분석법 유형: 헤비메틸
프라이머:
서열 번호:291
서열 번호:292
차단체:
서열 번호:293
프로브:
서열 번호:294
서열 번호:295
온도 사이클링 프로파일:
95℃에서의 활성화
95℃ 10분
50회 사이클
변성 95℃ 10초(20℃/초)
어닐링 56℃ 30초(20℃/초)
연장 72℃ 10초(20℃/초)
용융
95℃ 10초 20
40℃ 10초 20
70℃ 0초 0.1
냉각
40℃ 5초
관심 있는 게놈 영역:
서열 번호:1
분석법 유형: 헤비메틸
프라이머:
서열 번호:296
서열 번호:297
차단체:
서열 번호:289
프로브:
서열 번호:299
서열 번호:300
온도 사이클링 프로파일:
95℃에서의 활성화
95℃ 10분
50회 사이클
변성 95℃ 10초(20℃/초)
어닐링 56℃ 30초(20℃/초)
연장 72℃ 10초(20℃/초)
용융
95℃ 10초 20
40℃ 10초 20
70℃ 0초 0.1
냉각
40℃ 5초
관심 있는 게놈 영역:
서열 번호:166
분석법 유형: 헤비메틸
프라이머:
서열 번호:259
서열 번호:260
차단체:
서열 번호:261
프로브:
서열 번호:262
서열 번호:263
온도 사이클링 프로파일:
활성화: 95℃ 10분
55회 사이클: 95℃ 10초; 58℃ 30초; 72℃ 10초
용융 곡선: 95℃ 10초; 35℃ 20초; 95℃ 0초
냉각: 40℃ 5초
관심 있는 게놈 영역:
서열 번호:167
분석법 유형: 헤비메틸
프라이머:
서열 번호:269
서열 번호:270
차단체:
서열 번호:271
프로브:
서열 번호:272
서열 번호:273
온도 사이클링 프로파일:
95℃에서의 활성화
95℃ 10분
55회 사이클
변성 95℃ 10초
어닐링 56℃ 30초
연장 72℃ 10초
용융
95℃ 10초
40℃ 10초
실시예 2
전혈 내에서의 DNA 메틸화의 분석에 기초한 직장결장 암종 스크리닝 및/또는 진단에 적합한 바람직한 패널을 선택하기 위하여 하기 분석을 수행하였다.
참조 또는 임상 실험실 세팅에 사용하기 적합한 분석 플랫폼(라이트사이클러) 및 실시간 분석법(MSP 및/또는 헤비메틸)을 이용하여 각 마커의 성능을 분석하였다. 각 마커의 정확도에 대한 지표를 제공하기 위하여, 직장결장 암종 조직 및 전혈에서 독립적으로 각 마커의 성능을 시험하였다.
하기 서열로 이루어진 마커의 군으로부터 패널을 선택하였다:
서열 번호:376
서열 번호:378
서열 번호:27
서열 번호:26
서열 번호:24
서열 번호:1
서열 번호:165
서열 번호:25
서열 번호:28
서열 번호:378
서열 번호:163
표 2에 기재되는 바와 같이 하나 이상의 메틸화 특이적 분석법, 즉 MSP 및/또는 헤비메틸에 의해 각 마커를 분석하였다.
각 샘플에서 DNA의 총량을 정량하기 위하여, 이후 C3 분석법으로 일컬어지는 추가적인 분석법(메틸화 특이적이 아님)을 수행하였다. C3 분석법은 메틸화 상태와 무관하게 전체 DNA를 검출하는 바이설파이트 DNA 분석법이다. 하기 프라이머 및 프로브를 사용하였다:
프라이머: GGAGTGGAGGAAATTGAGAT 서열 번호:62
프라이머: CCACACAACAAATACTCAAAAC 서열 번호:63
프로브: TGGGTGTTTGTAATTTTTGTTTTGTGTTAGGTT 서열 번호:64
표 3에 기재되는 바와 같이 직장결장 암종, 인접한 정상 조직 및/또는 전혈 샘플에서 각 분석법을 이중으로 수행하였다.
시중에서 구입가능한 키트를 사용하여 DNA 추출을 수행하였고, 올렉 등의 문헌(1996)에 기재된 방법에 따라 약간의 개질과 함께 바이설파이트 전환을 수행하였다.
라이트사이클러 플랫폼을 사용하여 모든 분석법(C3 및 메틸화 특이적)을 수행하였다.
데이터 해석
DNA 농도의 계산
라이트사이클러 장치 소프트웨어에 의해 계산된 Cp(교차점 값) 및 강도 곡선을 사용하여 DNA 농도를 결정하였다. 메틸화 분석법 및 C3 분석법의 경우 각 웰의 CP 값을 표준 곡선에 대해 참조함으로써 DNA 농도를 계산하였다.
샘플 반복 실험
대부분의 경우, 각 분석법을 샘플 1개당 2회씩 실행하여 샘플 1개당 복수개의 측정치를 생성시켰다. 각 샘플에 있어서 등급은 다음과 같이 계산한다:
1. 모든 샘플 쌍에 대해 비 v1/v2를 계산한다.
2. 둘 다 0.1ng의 역치 미만이면 비를 =로 설정하고, 하나가 =이고 다른 하나가 역치보다 높으면 비를 100으로 설정한다.
3. 각 분석법에 있어서, 비가 2.5를 초과하는 샘플을 더 이상 분석하지 않는다.
4. 정확히 2회 반복 실험하지 않은 샘플의 경우, 임의의 등급을 취하지 않고서 평균을 구한다.
% 메틸화
C3 분석법을 이용하여 1ng DNA 미만으로 측정된 모든 샘플을 더 이상 고려하지 않았다. 각 샘플에 있어서, 메틸화 분석법을 이용하여 정량된 DNA의 측정된 농도/C3 분석법에 의해 정량된 샘플중 DNA의 농도로서 검출된 % 메틸화를 계산하였다.
3개의 상이한 역치 수준(표 참조) 및 모든 메틸화 수준에서(즉, 메틸화가 검출된 임의의 샘플은 양성으로 간주되었음) 메틸화를 검출하였다.
직장결장 암종 샘플 양성 검출 비로부터 각 분석법의 민감도를 결정하였으며, 민감도는 메틸화가 양으로 검출된(즉, 올바른 양성) 샘플의 %로서 결정되었다.
혈액 샘플 음성 검출 비(즉, 올바른 음성 검출 비)로부터 각 분석법의 특이성을 결정하였으며, 잘못된 양성을 분석된 샘플의 총수로부터 제하였다.
결과
개별 분석법에 의해 다양한 역치 내에서 측정된 메틸화된 분석된 샘플의 비율이 표 4(직장결장 암종 조직), 표 5(인접한 정상 조직) 및 표 6(전혈)에 기재된다.
도 30 내지 도 37은 2원 분포 플롯(도면의 위쪽 왼쪽) 및 명시된 컷-오프 점보다 높은 측정된 메틸화 수준(X-축)을 갖는 직장결장 암종 조직 및 전혈 (및 일부 경우 인접한 정상 조직) 샘플의 비율(Y-축)의 관련 다부류 분포 플롯(도면의 아래 쪽 왼쪽)을 도시한다. 각 도면의 오른쪽에는 민감도 대 특이성의 ROC 플롯이 있다. ROC 곡선은 진단 시험의 상이한 가능한 컷 지점에 있어서 잘못된 양성 비율에 대한 올바른 양성 비율의 플롯이다. 이는 선택된 컷 지점에 따른 민감도와 특이성 사이의 균형을 보여준다(민감도의 임의의 증가는 특이성의 감소를 수반함). ROC 곡선 아래의 면적(AUC)은 진단 시험의 정확도의 척도이다[면적이 클수록 더 우수하고, 최적치는 1이며, 무작위적인 시험은 0.5의 면적을 갖는 직사각형으로 도시되는 ROC 곡선을 가짐; 이건(J. P. Egan), Signal Detection Therory and ROC Analysis, Academic Press, 뉴욕, 1975 참조]. 각 ROC 플롯의 AUC 및 윌콕슨 p-값은 표 12에 기재된다.
단계
암종의 단계에 따른 직장결장 암종 결과의 추가적인 분석이 표 7에 기재된다. 상기 표에는, 두 가지 상이한 메틸화 역치(10% 초과 및 20% 초과)에 기초한 마커 민감도가 CRC의 모든 단계에 대해 기재된다. 대부분의 마커의 경우, 민감도는 모든 CRC 단계에 걸쳐 균일하여, 이들 마커는 스크리닝 또는 모니터링 시험에서 CRC의 모든 단계의 검출에 적합하다. 단계 II 암에서 민감도가 더 높은 경향이 있는 것으로 보인다. 덜 민감하고 더 특이적인 마커는 보다 초기 단계의 암을 확인하는 경향이 있고(예를 들어, 서열 번호:25(분석 3)), 스크리닝/모니터랑 시험의 민감도에 부가할 수 있을 뿐만 아니라, 다른 용도(생검, 대변 검사 등)에도 유용할 수 있다.
패널
직장결장 암종 및 전혈에서 분석법의 조합에 의해 다양한 역치 내에서 측정된 메틸화된 분석된 샘플의 비율이 표 8 내지 표 11에 기재된다. 각각의 경우, 표는 소정 역치 내의 샘플의 비율, 및 첫번째 마커만을 사용한 경우와는 대조적으로 두 마커를 모두 사용하는 경우 검출된 샘플의 증가도 나타낸다.
실시예 3
셉틴 9(그의 전사 변이형 Q9HC74 포함) 및 큰 샘플 세트에서 분석법의 성능을 유효화시킴으로써 전혈에서의 DNA 메틸화 분석에 기초한 직장결장 암종 스크리닝 및/또는 진단에 적합한 마커로서의 그의 패널을 확인하기 위하여, 하기 분석을 수행하였다.
기준 또는 임상 실험실 세팅에 사용하기에 적합한 어레이 플랫폼(라이트사이클러) 및 실시간 분석법(MSP 및/또는 헤비메틸)을 이용하여 마커의 성능을 분석하였다. 마커의 정확도의 지표를 제공하기 위하여, 직장결장 조직(인접한 정상 조직), 직장결장 암종 조직 및 전혈에서 독립적으로 각 마커의 성능을 시험하였다.
하기 프라이머 및 프로브를 사용하였다:
하기 프로토콜을 이용하여 표 2에 따른 라이트사이클러 프로브를 사용한 서열 번호:1(분석 7)을 수행하였다:
물: 10㎕의 최종 부피까지 채움
MgCl2: 3.5
전진 프라이머: 0.3
후진 프라이머: 0.3
차단체: 4
검출 프로브(형광): 0.15
검출 프로브(적색): 0.15
1a+1b 시약 패스트스타트(FastStart) 믹스: 1
DNA
라이트사이클러 프로그램:
활성화: 95℃ 10분
55회 사이클: 95℃ 10초(20℃/초); 56℃ 30초(20℃/초) 검출; 72℃ 10초(20℃/초)
용융 곡선: 95℃ 10초 20; 40℃ 10초 20; 70℃ 0초 0.1
냉각: 40℃ 5초
하기 프로토콜을 이용하여 표 2에 따른 택맨 프로브를 사용하는 서열 번호:1(분석 7)을 수행하였다:
프로토콜:
물: 10㎕의 최종 부피까지 채움
MgCl2: 3.5
프라이머 1: 0.3
프라이머 2: 0.3
차단체: 4
택맨 프로브: 0.15
1a+1b 시약(패스트스타트): 1
DNA: 10㎕
사이클링 조건
활성화: 95℃ 10분
50회 사이클: 95℃ 10초(20℃/초); 56℃ 30초(20℃/초) 검출; 72℃ 10초(20℃/초)
용융 곡선: 95℃ 10초 20; 40℃ 10초 20; 70℃ 0초 0.1
냉각: 40℃ 5초
각 샘플의 DNA의 총량을 정량하기 위하여 C3 분석법을 수행하였다. C3 분석법을 상기 실시예 2에서와 같이 수행하였다.
직장결장 암종, 인접한 정상 조직 및/또는 전혈 샘플 상에서 각 분석법을 2회씩 실행하였다. 두 세트의 샘플을 분석하였는데, 샘플 세트 1은 표 13에 기재된 바와 같고, 샘플 세트 2는 표 14에 기재된 바와 같다.
표 2에 상세하게 기재된 하기 분석법을 이용하여 샘플 세트 1을 분석하였다:
서열 번호:1(분석 2)
서열 번호:26(분석 6)
서열 번호:24(분석 5)
서열 번호:25(분석 3)
표 2에 상세하게 기재된 서열 번호:1(분석 7) 라이트사이클러(LC) 및 택맨(Taq) 변이형, 및 표 17에 상세하게 기재된 서열 번호:28(분석 2), 서열 번 호:24(분석 5b), 서열 번호:29(분석 2b)를 이용하여 샘플 세트 2를 분석하였다.
4ng보다 많은 DNA를 갖는 샘플만 분석하였다. 샘플 세트 1에서는, 27개의 혈액 샘플 및 91개의 직장결장 암 샘플을 분석하였다. 샘플 세트 2에서는, 26개의 혈액 샘플, 22개의 인접하지 않은 직장결장 조직 샘플 및 81개의 직장결장암 샘플을 분석하였다.
모든 분석법(C3 및 메틸화 특이적)은 라이트사이클러 플랫폼을 사용하여 수행하였다.
DNA 추출 및 바이설파이트 처리
제조업체의 지시에 따라 마그나 퓨어(Magna Pure) 방법[롯슈(Roche)]에 따라 모든 샘플로부터 DNA를 단리하였다. 정제로부터 생성된 용출물을 하기 바이설파이트 반응에 따라 전환시켰다. 바이설파이트 용액(5.89몰/ℓ) 354㎕ 및 라디칼 소거제(6-하이드록시-2,5,7,8-테트라메틸크로메인 2-카복실산, 다이옥세인 2.5ml중 98.6mg)를 함유하는 다이옥세인 146㎕와 용출물을 혼합하였다. 반응 혼합물을 99℃에서 3분간 변성시킨 후, 총 7시간동안의 하기 온도 프로그램에서 배양하였다: 50℃에서 분; 3분간 열스파이크(thermospike)(99.9℃); 50℃에서 1.5시간; 3분동안 열스파이크(99℃); 50℃에서 3시간. 이어, 밀리포어 마이크로콘(Millipore Microcon™) 칼럼을 사용하는 한외여과에 의해 반응 혼합물을 정제하였다. 본질적으로 제조업체의 지시에 따라 정제를 수행하였다. 이를 위하여, 반응 혼합물을 물 300㎕와 혼합하고, 한외여과 막 상에 로딩한 후, 15분간 원심분리시키고, 이어 1×TE 완충액으로 세척하였다. 이 처리에서 DNA는 막 상에 잔류한다. 이어, 탈설폰 화를 수행한다. 이를 위하여, 0.2몰/ℓ의 NaOH를 첨가하고 10분간 배양하였다. 이어, 원심분리(10분)를 수행한 다음, 1×TE 완충액으로 세척하였다. 그 후, DNA를 용출시켰다. 이를 위하여, 막을 10분간 따뜻한 1×TE 완충액(50℃) 75㎕와 혼합하였다. 제조업체의 지시에 따라 막을 뒤엎었다. 이어, 반복적인 원심분리를 수행하였으며, 이에 따라 DNA를 막으로부터 제거하였다. 라이트사이클러 실시간 PCR 분석법에 용출물 10㎕를 사용하였다.
반응 용액 및 열 사이클링 조건
서열 번호:26 분석법 6( 헤비메틸 분석법)
반응 용액:
물
MgCl2: 3.50mM(완충액이 1mM을 포함함)
프라이머 믹스: 0.30μM(각각)
차단체: 4.00μM
검출 프로브 믹스: 0.15μM(각각)
1a+1b 시약 패스트스타트 믹스: 1.00×
열 사이클링 조건:
활성화: 95℃ 10분
55회 사이클: 95℃ 10초(20℃/초); 56℃ 30초(20℃/초) 검출; 72℃ 10초(20℃/초)
용융 곡선: 95℃ 10초 20; 40℃ 10초 20; 70℃ 0초 0.1
냉각: 40℃ 5초
서열 번호:25 분석법 3( 헤비메틸 분석법)
반응 용액:
물
MgCl2: 3.50mM(완충액이 1mM을 포함함)
프라이머 믹스: 0.30μM(각각)
차단체: 4.00μM
검출 프로브 믹스: 0.15μM(각각)
1a+1b 시약 패스트스타트 믹스: 1.00×
열 사이클링 조건:
활성화: 95℃ 10분
55회 사이클: 95℃ 10초(20℃/초); 56℃ 30초(20℃/초) 검출; 72℃ 10초(20℃/초)
용융 곡선: 95℃ 10초 20; 40℃ 10초 20; 70℃ 0초 0.1
냉각: 40℃ 5초
서열 번호:24 분석법 5B( 헤비메틸 분석법)
반응 용액:
물
MgCl2: 3.00mM*
전진 프라이머: 0.30μM
후진 프라이머: 0.30μM
차단체: 4.00μM
검출 프로브 형광: 0.15μM
검출 프로브 적색: 0.15μM
1a+1b 시약 믹스: 1.00×
열 사이클링 조건:
95℃에서의 변성
95℃ 10분
55회 사이클:
변성 95℃ 10초(20℃/초)
어닐링 58℃ 30초(20℃/초) 검출
연장 72℃ 10초(20℃/초)
용융
95℃ 10초 20; 35℃ 20초 20; 95℃ 0초 0.1
서열 번호:24 분석법 5( 헤비메틸 분석법)
반응 용액:
물
MgCl2: 3.00mM(완충액이 1mM을 포함함)
전진 프라이머: 0.30μM
후진 프라이머: 0.30μM
차단체: 4.00μM
라이트사이클러 프로브: 0.15μM
라이트사이클러 프로브: 0.15μM
1a+1b 시약 믹스: 1.00×
열 사이클링 조건:
95℃에서의 변성
95℃ 10분
55회 사이클:
변성 95℃ 10초(20℃/초)
어닐링 58℃ 30초(20℃/초) 검출
연장 72℃ 10초(20℃/초)
용융
95℃ 10초 20; 35℃ 20초 20; 95℃ 0초 0.1
서열 번호:1 분석법 2( MSP 분석법)
반응 용액:
물(3315932)
MgCl2(2239272): 3.50mM(*)
전진 프라이머: 0.60μM
후진 프라이머: 0.60μM
검출 프로브: 0.30μM
1a+1b 시약 패스트스타트 믹스: 1.00×
열 사이클링 조건:
활성화: 95℃ 10분
50회 사이클: 95℃ 15초; 62℃ 45초
냉각: 40℃ 5초
서열 번호:1 분석법 7( 라이트사이클러 프로브 헤비메틸 분석법)
반응 용액:
물
MgCl2: 3.50mM(완충액이 1mM을 포함함)
프라이머 1: 0.30μM
프라이머 2: 0.30μM
차단체: 4.00μM
검출 프로브 (형광): 0.15μM
검출 프로브 (적색): 0.15μM
1a+1b 시약 (패스트스타트): 1.00×
열 사이클링 조건:
활성화: 95℃ 10분
50회 사이클: 95℃ 10초(20℃/초); 56℃ 30초(20℃/초) 검출; 72℃ 10초(20 ℃/초)
용융 곡선: 95℃ 10초 20; 40℃ 10초 20; 70℃ 0초 0.1
냉각: 40℃ 5초
서열 번호:1 분석법 7( 택맨 헤비메틸 분석법)
반응 용액:
물
MgCl2: 3.50mM(완충액이 1mM을 포함함)
프라이머 1: 0.30μM
프라이머 2: 0.30μM
차단체: 4.00μM
검출 프로브 1: 0.15μM
검출 프로브 2: 0.15μM
1a+1b 시약 믹스: 1.00×
열 사이클링 조건:
활성화: 95℃ 10분
50회 사이클: 95℃ 10초(20℃/초); 56℃ 30초(20℃/초) 검출; 72℃ 10초(20℃/초)
용융 곡선: 95℃ 10초 20; 40℃ 10초 20; 70℃ 0초 0.1
냉각: 40℃ 5초
서열 번호:28 분석법 2( 헤비메틸 분석법)
반응 용액:
물
MgCl2: 3.50mM(완충액이 1mM을 포함함)
프라이머 1: 0.30μM
프라이머 2: 0.30μM
차단체: 4.00μM
검출 프로브 1: 0.15μM
검출 프로브 2: 0.15μM
1a+1b 시약 믹스: 1.00×
열 사이클링 조건:
활성화: 95℃ 10분
50회 사이클: 95℃ 10초(20℃/초); 56℃ 30초(20℃/초) 검출; 72℃ 10초(20℃/초)
용융 곡선: 95℃ 10초 20; 40℃ 10초 20; 70℃ 0초 0.1
냉각: 40℃ 5초
서열 번호:29 분석법 2B( 헤비메틸 분석법)
반응 용액:
물
MgCl2: 3.50mM(완충액이 1mM을 포함함)
프라이머 1: 0.30μM
프라이머 2: 0.30μM
차단체: 4.00μM
검출 프로브 (형광): 0.15μM
검출 프로브 (적색): 0.15μM
1a+1b 시약 (패스트스타트): 1.00×
열 사이클링 조건:
활성화: 95℃ 10분
50회 사이클: 95℃ 10초(20℃/초); 58℃ 30초(20℃/초) 검출; 72℃ 10초(20℃/초)
용융 곡선: 95℃ 10초 20; 40℃ 10초 20; 70℃ 0초 0.1
서열 번호:29 분석법 2( 헤비메틸 분석법)
반응 용액:
물
MgCl2: 3.50mM(완충액이 1mM을 포함함)
프라이머 1: 0.30μM
프라이머 2: 0.30μM
차단체: 4.00μM
검출 프로브 1: 0.15μM
검출 프로브 2: 0.15μM
1a+1b 시약 믹스: 1.00×
열 사이클링 조건:
활성화: 95℃ 10분
55회 사이클: 95℃ 10초(20℃/초); 56℃ 30초(20℃/초) 검출; 72℃ 10초(20℃/초)
용융 곡선: 95℃ 10초 20; 40℃ 10초 20; 70℃ 0초 0.1
냉각: 40℃ 5초
데이터 해석
DNA 농도의 계산.
라이트사이클러 장치 소프트웨어에 의해 계산된 Cp(교차점 값)를 사용하여 DNA 농도를 결정하였다. 메틸화 분석법 및 C3 분석법의 경우 각 웰의 CP 값을 표준 곡선에 대해 참조함으로써 DNA 농도를 계산하였다.
대부분의 경우 각각의 분석법을 샘플 1개당 2회씩 실행하여, 샘플 1개당 복수개의 측정치를 수득하였다.
% 메틸화
C3 분석법을 이용하여 4ng DNA 미만으로 측정된 모든 샘플을 더 이상 고려하지 않았다. 각 샘플에 있어서, 메틸화 분석법을 이용하여 정량된 DNA의 측정된 농도/C3 분석법에 의해 정량된 샘플중 DNA의 농도로서 검출된 % 메틸화를 계산하였다.
3개의 상이한 역치 수준(표 참조) 및 모든 메틸화 수준에서(즉, 메틸화가 검출된 임의의 샘플은 양성으로 간주되었음) 메틸화를 검출하였다.
직장결장 암종 샘플 양성 검출 비로부터 각 분석법의 민감도를 결정하였으며, 민감도는 메틸화가 양으로 검출된(즉, 올바른 양성) 샘플의 %로서 결정되었다.
전혈 샘플 음성 검출 비(즉, 올바른 음성 검출 비)로부터 각 분석법의 특이성을 결정하였으며, 잘못된 양성을 분석된 샘플의 총수로부터 제하였다.
결과
개별 분석법에 의해 소정 역치 내에서 측정된 메틸화된 분석된 샘플의 비율 또는 수가 표 15(샘플 세트 1) 및 표 16(샘플 세트 2)에 기재된다. 두 반복 실험중 하나 이상이 소정 역치 내에서 양성인 것으로 검사된 경우, 샘플을 양성으로 간주하였다. 패널의 하나 이상의 분석법을 이용하여 소정 역치 내에서 측정된 메틸화된 분석된 샘플의 비율 또는 수를 결정함으로써 패널 데이터를 집계하였다. 두 반복 실험중 하나 이상이 소정 역치 내에서 양성인 것으로 검사된 경우, 샘플을 양성으로 간주하였다.
서열 번호:1 분석법 2를 14개의 유방암 샘플, 12개의 직장결장암 샘플 및 10개의 전혈 샘플의 세트(샘플 세트 3)에서 추가로 시험하였다. 개별적인 분석법에 의해 소정 역치 내에서 측정된 메틸화된 분석된 샘플의 비율 또는 수는 표 18에 기재된다.
실시예 4: 기타 암
유전자 셉틴 9(그의 전사 변이형 Q9HC74) 및 큰 샘플 세트에서 분석법의 성능을 유효화시킴으로써 전혈에서의 DNA 메틸화 분석에 기초한 기타 암의 스크리닝 및/또는 진단에 적합한 마커로서의 그의 패널을 확인하기 위하여, 하기 분석을 수 행하였다.
표 2에 따른 서열 번호:1의 헤비메틸 분석법 7을 이용하여 마커의 성능을 분석하였으며, 반응 조건은 실시예 2에 따랐다.
표 20은 각 부류에서 시험된 샘플의 수, 및 두 반복 실험이 모두 메틸화에 대해 양성인 것으로 검사된 샘플의 수를 나타낸다. 도 3은 기타 암에서 측정된 메틸화 수준을 보여주고, 볼 수 있는 바와 같이 유전자는 여러 암 유형을 불문하고 메틸화된다. 그러나, 간암만이 직장결장암과 동일하거나 그보다 높은 비율로 메틸화된다. 도 4는 다른 비-암성 질환에서 측정된 메틸화 수준을 보여주고, 볼 수 있는 바와 같이 신우신염만이 직장결장암과 동일하거나 그보다 높은 비율로 메틸화된다.
실시예 5: 바이설파이트 서열 결정
셉틴 9 유전자의 서열 결정
유전자 셉틴 9는 4개(앙상블 데이터베이스에 관한 기존 논의 참조) 내지 6개 이상의 상이한 전사 변이형[5' 말단에서, 러셀(Russell) 등, Oncogene 2001년 9월 13일; 20(41):5930-9 참조]을 갖는 것으로 생각되었다. 러셀 등에 의해 인용된 변이형중에서, 앰플리콘은 4개의 변이형(알파, 베타, 감마 및 엡실론)을 커버하는 CpG 섬 또는 CpG가 풍부한 영역을 커버하도록 디자인되었다. 변이형중 2개, 즉 엡실론 및 감마에 겹치는 2개의 CpG 섬이 있다. 베타 변이형은 감마 CpG 섬에 의해 조절되는 것으로 보인다.
12명의 환자로부터의 샘플을 분석하였으며, 상기 기재된 바와 같이 헤비메틸 분석법에 의해 셉틴 9 메틸화 수준을 이미 정량하였다. 2개의 샘플은 20%보다 높은 메틸화을 가졌고(샘플 C 군), 4개의 샘플은 10% 내지 20%의 메틸화를 가졌으며(샘플 B 군), 6개의 샘플은 10% 이하의 메틸화를 이미 나타내었다(샘플 A 군).
뿐만 아니라, 뚜렷한 질환이 없는 환지로부터의 3개의 전혈 샘플의 DNA를 또한 알파 및 베타 앰플리콘에 대해 사용하였다(샘플 N 군).
DNA 추출 및 바이설파이트 처리
제조업체의 지시에 따라 퀴아젠(QIAGEN) 게노믹-팁(Genomic-Tip) 500/G 또는 100/G를 사용하여 DNA를 단리하였다. 이어, 하기 바이설파이트 반응에 따라 정제된 게놈 DNA를 전환시켰다.
100ul중 DNA 2ug을 바이설파이트 용액(뉴클레아제를 함유하지 않는 물 22ml중 중아황산나트륨 10.36g 및 아황산나트륨 2.49g) 354㎕ 및 라디칼 소거제(6-하이드록시-2,5,7,8-테트라메틸크로메인 2-카복실산, 다이옥세인 8.2ml중 323mg)를 함유하는 다이옥세인 146㎕와 혼합하였다. 바이설파이트 반응은 다음과 같았다:
Figure 112007081632685-PCT00001
이어, 밀리포어 마이크로콘(Millipore Microcon™) 칼럼을 사용하는 한외여과에 의해 반응 혼합물을 정제하였다. 제조업체의 지시에 따라 정제, 더욱 구체적으로는 탈설폰화 및 세척을 수행하였다:
Figure 112007081632685-PCT00002
이어, 바이설파이트 TE 완충액(50℃로 미리 가온함; 트리스 10mM중 EDTA 0.1mM) 50㎕를 막에 첨가하고 진탕(1000rpm)하면서 10분간 배양하였다. 칼럼을 1.7ml들이 저-체류 관 내로 부어넣고 1000g에서 7분간 회전시켜 DNA를 용출시켰다. 대조용 서열(HB14)의 실시간 PCR 분석법에 의해 DNA 농도를 결정하였다.
증폭
앰플리콘 및 PCR 프라이머에 대한 표 21 참조. 명칭에 "rc"를 갖는 앰플리콘을 Bis2 가닥으로부터, 다른 것은 Bis1 가닥으로부터 증폭시켰다.
25ul 반응에서 하기 조건을 이용하여 관심 있는 단편을 증폭시켰다.
PCR 반응:
Figure 112007081632685-PCT00003
사이클링 조건:
94℃에서 3분; 94℃에서 20초; 54℃에서 30초; 72℃에서 45초(38 내지 42회 사이클); 72℃에서 10분
PCR 생성물의 정제
제조업체의 지시에 따라 몬티지(Montage™) DNA 겔 추출 키트로 PCR 생성물을 정제하였다. 간단히, 1% 개질된 TAE(표준 TAE의 1.0mM EDTA 대신 0.1mM EDTA 함유) 아가로즈 겔 상에서 PCR 반응을 실행하였다. 관심 있는 DNA 밴드를 절단하고 절제해냈다. 몬티지 DNA 겔 추출 장치에 겔 슬라이스를 위치시키고, 5000g에서 10분간 회전시켜 DNA 용액을 수집하였다. 정제된 DNA를 10ul로 추가로 농축시켰다.
TA 클로닝
제조업체의 지시에 따라 인비트로젠(Invitrogen) 토포(TOPO; 등록상표) TA 클로닝 키트를 사용하여 PCR 생성물을 클로닝 및 전파하였다. 간단히, 정제 및 농축된 PCR 생성물 2ul를 토포 클로닝 반응에 사용하여, 이를 벡터 pCR(등록상표)2.1-TOPO 내로 클로닝하였다. 화학적으로 경쟁하는 이. 콜라이(E. coli) 균주 TOP10으로 형질전환을 수행하였다.
서열 결정
개별 콜로니를 찍어서 LB(선택을 위해 50ug 카베니실린/ml LB) 중에서 배양하였다. 하룻밤 배양액 1ul를 콜로니 PCR을 위해 20ul 부피로 사용하였다:
PCR 믹스
2.5ul 10×DyNAzyme 완충액
2.5ul 2mM dNTP
1.25ul M13F 프라이머(10uM)
1.25ul M13R 프라이머(10uM)
0.25ul DyNAzyme 폴리머라제
12.25ul ddH2O
사이클링 조건:
94℃에서 3분; 94℃에서 1분; 55℃에서 1분; 72℃에서 1분(36회 사이클); 72℃에서 10분
표준 프로토콜을 사용하여 콜로니 PCR 앰플리콘 정제 및 서열 결정 판독을 수행하였다. 사용되는 서열 결정 프라이머는 M13 역 프라이머 또는 초기 PCR 생성물을 생성시킨 앰플리콘 특이적 프라이머중 하나였다.
결과
도 5 내지 도 29는 출원인 소유의 소프트웨어(추가의 정보를 위해서는 WO 2004/000463 호 참조)에 의해 분석된 감마 앰플리콘의 바이설파이트 서열 결정 데이터로부터 생성된 매트릭스를 제공하였다. 매트릭스의 각 칼럼은 한 샘플의 반복 실험에 대한 서열 걸정 데이터를 나타내고, 각 샘플의 모든 반복 실험을 한 블록에 함께 군을 지었다. 매트릭스의 각 횡렬은 단편 내에서의 단일 CpG 부위를 나타낸다. 증폭물의 CpG 수는 매트릭스의 왼쪽에 도시된다.
각 CpG 위치에서 측정된 메틸화의 양은 밝은 회색(0% 메틸화) 내지 중간 회색(50% 메틸화) 내지 어두운 회색(100% 메틸화)의 색상으로 표시된다. 일부 증폭물, 샘플 또는 CpG 위치는 성공적으로 서열이 결정되지 못하였고, 이들은 백색으로 도시된다.
도 5 내지 도 29는 실시예 5에 따른 바이설파이트 서열 결정 데이터의 매트릭스를 제공한다. 매트릭스의 각 칼럼은 한 샘플의 반복 실험에 대한 서열 결정 데이터를 나타내고, 각 샘플의 모든 반복 실험은 한 블록 내에 함께 무리를 지었다. 매트릭스의 각 횡렬은 단편 내의 단일 CpG 부위를 나타낸다. 증폭물의 CpG 수는 매트릭스의 왼쪽에 도시한다.
각 CpG 위치에서 측정된 메틸화의 양을 밝은 회색(0% 메틸화) 내지 중간 회색(50% 메틸화) 내지 어두운 회색(100% 메틸화)의 색상으로 나타낸다. 일부 증폭물, 샘플 또는 CpG 위치는 성공적으로 서열이 결정되지 못하였고, 이들은 백색으로 도시된다.
도 5 내지 도 12는 10% 내지 20%의 메틸화를 갖는 것으로 이미 정량된(헤비메틸 분석법에 의해) 4개의 샘플에서 표 21에 따른 게놈 서열의 바이설파이트 전환된 증폭물의 서열 결정의 개관을 제공한다.
도 13 내지 도 20은 20%보다 높은 메틸화를 갖는 것으로 이미 정량된(헤비메틸 분석법에 의해) 2개의 샘플에서 표 21에 따른 게놈 서열의 바이설파이트 전환된 증폭물의 서열 결정의 개관을 제공한다.
도 21 내지 도 22는 3명의 건강한 개체로부터의 혈액 샘플에서 표 21에 따른 게놈 서열의 바이설파이트 전환된 증폭물의 서열 결정의 개관을 제공한다.
도 23 내지 도 29는 10% 미만(0%보다는 높음)의 메틸화를 갖는 것으로 이미 정량된(헤비메틸 분석법에 의해) 6개의 샘플에서 표 21에 따른 게놈 서열의 바이설파이트 전환된 증폭물의 서열 결정의 개관을 제공한다.
실시예 6
서열 번호:159 내지 서열 번호:163에 따른 게놈 서열의 바이설파이트 처리된 변이형의 분석에 적합한 추가의 분석법이 표 22에 기재된다. 당해 분야에 공지되어 있는 프로토콜에 따라 게놈 DNA의 바이설파이트 처리를 수행할 수 있다[예를 들어, 올렉 등, A modified and improved methods for bisulfite based cytosine methylation analysis, Nucleic Acids Res . 24:5064-6, 1996]. 당해 분야의 숙련자는 적합한 사이클링 조건을 알 것이며, 이들 조건은 표 22에 도시되는 바와 같이 올리고머의 융점으로부터 유추될 수 있다.
Figure 112007081632685-PCT00004
Figure 112007081632685-PCT00005
Figure 112007081632685-PCT00006
Figure 112007081632685-PCT00007
Figure 112007081632685-PCT00008
Figure 112007081632685-PCT00009
Figure 112007081632685-PCT00010
Figure 112007081632685-PCT00011
Figure 112007081632685-PCT00012
Figure 112007081632685-PCT00013
Figure 112007081632685-PCT00014
Figure 112007081632685-PCT00015
Figure 112007081632685-PCT00016
Figure 112007081632685-PCT00017
Figure 112007081632685-PCT00018
Figure 112007081632685-PCT00019
Figure 112007081632685-PCT00020
Figure 112007081632685-PCT00021
Figure 112007081632685-PCT00022
Figure 112007081632685-PCT00023
Figure 112007081632685-PCT00024
Figure 112007081632685-PCT00025
Figure 112007081632685-PCT00026
Figure 112007081632685-PCT00027
Figure 112007081632685-PCT00028
Figure 112007081632685-PCT00029
Figure 112007081632685-PCT00030
Figure 112007081632685-PCT00031
Figure 112007081632685-PCT00032
Figure 112007081632685-PCT00033
Figure 112007081632685-PCT00034
Figure 112007081632685-PCT00035
Figure 112007081632685-PCT00036
Figure 112007081632685-PCT00037
Figure 112007081632685-PCT00038
Figure 112007081632685-PCT00039
Figure 112007081632685-PCT00040
<110> Epigenomics AG; Lofton-Day, Catherine; Sledziewski, Andrew; Lesche, Ralf; Schuster, Matthias; Distler, Juergen; Tetzner, Reimo; Hildmann, Thomas; Model, Fabian; Song, Xialong <120> METHODS AND NUCLEIC ACIDS FOR ANALYSES OF CELLULAR PROLIFERATIVE DISORDERS <130> 47675-187 <140> <141> 2006.04.17 <150> US 60/672,242 <151> 2005.04.15 <150> US 60/676,997 <151> 2005.05.02 <150> US 60/697,521 <151> 2005.07.08 <150> US 60/704,860 <151> 2005.08.01 <150> US 60/709,318 <151> 2005.08.17 <150> US 60/723,602 <151> 2005.10.04 <150> US 60/787,402 <151> 2006.03.30 <160> 390 <210> 1 <211> 219909 <212> DNA <213> Homo Sapiens <400> 1 cgttacccga gttgtaaagg gcggctccct gtgtctgccc cgctgcaccg atacaccgag 60 ctgcgcacgg tgcccagcgc agggagaaca aatgatcatc tgtccaacgc gcccatttac 120 aggtgaggaa actaaggctc caactcaatc gacgcactct gcccttttga ttaccagaaa 180 agtagcagga caggtgtcct gtcccgccct accccggccc actaagccgg caccccggct 240 ccgacccccg gctgtgcccg gcgccgccgc ggtgcccggc gccgccgcct cgcccggcgg 300 ggccgcccgg agcgcccgca cctccgcccg cttccacctg gccgggcccg ccccgcccgg 360 actcgggact gggaagtgcg gcgactcccg gaaccagcca ttggcgccag cgcggggagc 420 tgggggtgca gagctgcggg cgcggcgggc cacgcaggcg gcccccaccc ccggcctggc 480 ctggtctggt ctggtctgcg ctgccgcgcg ggggcgcccc ctcccaggcc cggcgcccgc 540 cagccccgct ccgccaggtg cagcgcagcg caggggtggg cgggggtggg gctcggcgcg 600 cacgttcacg gggcggggag ggggcgggtc aggggcggga ccacagccgg ctgggccggg 660 gttctatgcg catctccggg gaggggcggg gcgggggcgg ggccggggcg gggcccggtc 720 ggtgcactcc agacggcggg ccgccccctc ttcccgcctt cctactaccg gcccaggatt 780 agcgccctgg gagcgcgcgc cccgctgcct cgccgccaca ctttcctggg agcggcggcc 840 acggaggcac catgaagaag tcttactcag gtgggcttcg cgcccggggt ggggaggggt 900 cggtgtcccg ggaccagcgc tgctcacctg agtgcctgcg gccgggagtg gcgaggcgcc 960 cccggagctg agcgagtccc cgcggcgggc acactgcagg tcgagttcct cccaggacag 1020 ggccgctgtc gggccgcttt cgacctgagc cgaccgtccc ctgcgctgtc tccagccctt 1080 gctcgagtgt cggaggggct gccctggggg acgctccctc ttcctcgccc cttgcaccct 1140 cgcaggaatc gctgactttc caggtcggcc gggtgctttg ggtccctgtg cgtctgtgtg 1200 ggtgaatggg gtcggggcta ggtggagggg tgtccttggg ttcagcctct agggctggtg 1260 gtccaggccg cagcatcctt tcttcggatt ctcttcggtt tctcctctac ttagtggggc 1320 acgggacggc ctccagatgg gaccgtccag cagcgcccaa acttggcgac tcgggttcac 1380 gttttgcgct caggacgccg cccgcggctg acatcctcac tccaccctag cagggcccgc 1440 cttaagtagg cgaagggggc ctgacttggg cctcaccatg agccggttca ggagctttca 1500 tttcataaga ggctcccgct ctggcactct gaagttccat ttcacagatg ggcacaccga 1560 ggccacaagg gcaggttaag agaaatccag atcttcatta tttgtctttt ccttcctttt 1620 ttttttcctt tgtggttttc tccaaaggat ccaggcaggc aggatccttt gtcctcctca 1680 gtcctcaaat tataaatagc gtctcctctt ctaaatctag aaaccgtttg tttaatgtcc 1740 ctcctttaat tcattcagat agaaaggtac ctgccaagga tccatgaatt aatttttatt 1800 gataggagaa cagaatcatg ggccttagtt ggaggtgaag gagtcatcgg ggccatcccc 1860 ctgcctttgg gccattgtcg gtttcctctg gctttccata tttaggaacc aaaatgagtg 1920 ataaagtacc ttgtctcaaa gaggattact cagaacttcc ccgaaaatac ccttctgggt 1980 cagtagctta gaatttcaac tttcacccgg ttgttgcgaa caagatggcc ctctacgcac 2040 ccggagcaca gctctgtcag gagcgtgggt gggttggtgt gctggtgggc gggagcgggc 2100 ttccaggtgg cacatgcttg gttttggcac cggggcttcc tccccaacat gctccaaata 2160 cttgagattg ttgtggggat cgcgcggtgc atggcccttt ccaggggatc tctagcccgc 2220 ccagggaggg ccctttgccc ttggtttctt acactttacc tcccactggt gggtccagac 2280 agtgggggtg accggggtcc tcccaggtcg tgggtcctgg gttttttctg cggagaccct 2340 cctgcacaga tgccggaagg gccctgaggc aggcttggag tctctgcacc tgcggcttac 2400 tgggaggtgg ggagaccatc acttgtcctt ttctcctctc ctccacacac acctacccca 2460 cccctcactg ggtttctttt tttttttttt ttttaaaaaa aaggacagaa ccttttgcag 2520 taggtggaag tagagtttgt ggagtgagca ggaaccaact cttgtacagc agcctcggtg 2580 cctccttgtg tttacctaaa ggggcaggcc cctctgagga tgggggaagg gagggctcag 2640 accatttctg gtttgctccc tgcttggcag tggcccaagg tgtgctgggt cactgtgttg 2700 cagttgtatg gagtgggact ggagggggct gatggtgggg gtggcctctt gccctcattc 2760 tgagtgtcct ggagctgtct tggcaccagc ccttttccgg gtacgggcac tcgcaggagt 2820 caggctgacc ccccaacaag ccatcgacac catgaaatta aggaaagcag caaaagatgt 2880 taaaaatccc ccaaggctct gacaatccaa ggacaacagg aaggtcttta ttttttcatc 2940 tagactgtgc gggattattg cttccagacc tgtatgtggg cttcagaata aacggaatga 3000 ccataatgtt gttcccggta gacctggttt gaacattcgt gagcctctga aaaggagaaa 3060 gattttagaa ggatgtgttg gggcaatctc aagtaccgtg ggtctataga cagtcatcga 3120 agacacttta tgtgctgggc acacatggcc aagtctgagt gggtacagaa atggtaatga 3180 gatatagtcc ttgcctgcag agaacttaca ttctcaccgg gagtcaggat gagggcgaga 3240 caccagctca ttaacaccct tccctcctga gcagttcagc ctccaaatac tacaggaatg 3300 ccccggaggt tttaggtgga ggtgagattg agctgggcct tgaggaagga gaagtcttga 3360 gtagtggaga ataaaaaggg acttggccag gtgcgcttga agtcccagct actcaggagg 3420 ctgagacacg aggatcgctt gagcccagga ggctactcag gaggctgaga cacgaggatc 3480 gcttgagccc aggaggctac tcaggaggct gagacaggag gatcgcttga agccaggagt 3540 tcaaggctgc agccctgtga cagcgcctgg aaatagacac ggcactccag cctgggtggc 3600 gtcatgagac cccatctgta agaaggtctt ttccaatgcg gaaggcagca agggcccaca 3660 cagggcagct gcaggatcca gggggacact ggggacaggt tctctctggc agctccactg 3720 ctgctccagg ctttcccgat tgcctcaccc ggccttccaa tggggtggag gtagtggtag 3780 tctacaggca gtgtggtcca gtggttacac ttgggggctc agagccgcca gccccttggg 3840 attaaatctc accaggctgc gcctctccct gtggcacaag gttctcacct catgcatctc 3900 atttgcctca tttgtttttt tgtgtgtgtg gtgtttttta attttattta tttatttatt 3960 tttgagacgg agtctcactc tgtctcccag gctggagtgc aatggcatga tctcagctta 4020 ctgcaacctc cgcctcccag gttcaagtga ttctcctgcc tcagcctcct gagtggctgg 4080 gattgtagga acgtgccact gcgcccagct aatttttata tttttactag agatggggtt 4140 tcaccatgtt ggtcaggctg atctcgaact cctgacctcg tgatctgcct gccttggcct 4200 cccaaagtgc tgtgattaca ggcatgagcc accacgccca gcctgcctca tttgttaaat 4260 gggacagtgc tatgttgttg taaaggttaa acgagttcat atttgaaaaa gctgagaaat 4320 gcctgctctg taacctgtta gctgctgtca tgatcatgat tgtcattgac aggaggatgg 4380 agaaggctgg ggttacgcca ttgctaggac gttccagaag cctccatgat cttcccttac 4440 tgtggtcaga gcatggtgca gggtctctcc cccagcccct cagcactgga gccagctgca 4500 ctgtacccgc cctggctctc taggttctga gttttgggac tccctttgca tactaggtca 4560 catggaactt gccgtcattc ccaggctccc ctggaaactc tctgtgggtg gcagcggcag 4620 gaggacttac ccgaggccga tgagccacag aagcgggact gaggttgcgt cacaccccta 4680 ctggcacctg ggaattactc tggagattct ttttttattt tttatttttt tgagatggag 4740 tcttgctctg ttgcccaggc tggagtgcag tggcacgatc tcggttcact gcaacctctg 4800 cctcccaggt tcaagcaatt ctcatgcctc agcctcctga gtagctggga ttacaggcat 4860 gtgccaccgt gcccagctaa tttttgtatt ttttagtaga gatggggttt taccatactg 4920 gccaggctgg tctcgaactc cggacctcag gtgatccacc cgcctcagcc tcccaaagtg 4980 ctgggatcac aggcatgagc caccgtgccc agccactctg gagtttctct gtggctttca 5040 ggagattcct gaaggggcac cagccacgat taaaaagctc tatgctgtcg tgacttctga 5100 gtcctgggca gggagggagg ctgcacccac acaggaagca gcttctgccg tgattcagtg 5160 tgctggctcg ccgtggtgga cagggctgca ccctcaccca gcgccccggg agctgactta 5220 cgggaagggc aaggaattgc accctcagag aacacttccc cagtcagcta acccggtgac 5280 aggcgagcgt gggaagggca caagcacagg gtttcttcct cttctccccc agccccgtct 5340 ccgcgcctgt tctcgctgcc tcttgcctcc tcacgtccaa gcttgtctgc tctggcgcat 5400 tcaggggacc tggactggag agaaaaagcc acctcgtacg gttagtctgt ggctctgtct 5460 gacttgtgtc ctccgccgag gcccctcagt tgtgagacag ctggctgagc ctaagtcctg 5520 gggccagccc tctccctagt ctgttgcaaa ggtagaaagg catgcccagg caggggccac 5580 ctgccctgcc cgctcacgcc agaccgcagg cacttgcccg tcagatctcc ccggcctgcc 5640 cagagggatt ctgatagccg agggcaatgc acctggcagc ggagcattgc gtttgcgaca 5700 gtccaccttc ttcctggaac caccccccac aagtgtgacc agctcaagcc aggacaggta 5760 cagggggacc caggattgcc acttaggggc agtggtctgg aatccaggtc caggtgacat 5820 gggagccaac cctctgcttg gagatcccag gtgggtgttt gcagaggaca tctcacttga 5880 ggacccatgg aaggggacac ttcccacccc ctacctggtc cttgggctgc cctcctctga 5940 cactctcctg ccatcccagg cagccctgac agccccatgt gactgggacc tagaggtggc 6000 ccctgtttcc gccccagtgt ttgtccacag gcagtgttgc gtgggctctg aagtttgcct 6060 aagatggacc tgataagggg agttcagtac acatcagtgc aggcccggcc agggggtgat 6120 gatggcagtt cctgggcaga tccagctggc tttagggtag gaggggctcc agagagaggc 6180 tccaggcccc taggggtgtg aacctttggg gtgaggcggg aagtgacgcg ctgggttcct 6240 gcgcctctgt ttgttggagc tattaccttg gaaacatccc agctctaggc ggttgccagg 6300 gatttatggg gatcagtggg tgccaatccc tgggtgaagc cctcggggct tgtacacagc 6360 acacagcgct gtggccccat ggctcacttt gctgtgtgaa gtggctcagt ctccgggaga 6420 gtccttagcc aggcaggcct gacggcaact gccaggtcat ggtgatctgg aatcgctgac 6480 caaagggagt cagtcctggt gggtggaggg acttggtggg cagccatcgt gatgccaggc 6540 atggggatcg tgtgtcaccc aggcctgtgg gtgccgagct tctgtgggag cagtgaagtg 6600 cccccgtggc cgatgggctg gtcacccctg cccctttcct gatgtgacag ttgtgcctgg 6660 gccccgggaa atttgccagg aggcctggca ttggcctgct ctactggagc ggccctgctg 6720 agctgtgagc tgcccgtctc cctgaggttc ctagcccatt tcaactctcc atgtggattt 6780 ggtcattcat tccagaagcg tctgccgggc gctgctgagt gtcaggttct gtttgcctcc 6840 tctcctgtac gctggaggct ctgggcacca gctctgcagg gtggcctggc cttgggtctc 6900 cagggtagag catggcactc tctgctccca gcccagtttc tctctgcttt atctccctga 6960 ccccaccctg ggcatgggcc catttgcagc ccctgtgaag ggagacattg agctgttgct 7020 ggcagaggag gggcggctcc tgggcactgc ttgccaatgg cctctcggca gctctgtgac 7080 agctgagctt tgttcccagc ctaatctgac ctggttctcc aaagcatgac tgttggcagc 7140 ctgaaaacct ccaggacagg aaacaggagt ggcgcaggga atgtaagatg atcccagctt 7200 caagtcactg ggcggccctt agacccaggc tgcctgctgt ctctggcagg aactcaagtc 7260 gctggtcatc ctcagagcgg tgttggcccg gggccttcag tggcctttgt gtctgggtga 7320 gaggaaccct ggatggccac tctgccctga gtgtgtgggt ccccagaagt gctgggttag 7380 ggggcacgga gggccagaaa gtcccctttg gagcgctgga ctctctcgct gactcctacc 7440 ccaccccggc ctggggtttc agagaagggg tccaggcagg agtgtcatct tttctcaatg 7500 gggatgtggc ttcagtctct gtccaggtgg gtgcattgct ctctttccgg ctcctcccag 7560 gctgcttaaa tgacctgtga cgaggcctgc gccatggccg gggccctctg cttttcccag 7620 cgctgcacct gggaaccagg ggttgggccc cggaagccga ggatgtccct gaatgccatg 7680 cctgggcacc tgtcctggcc aggcgaggcg tgttggggca gcggctgaga tgggagcagc 7740 agcattgcct gccaggtttg agatgggccc cgggtgagtg tggttaccag gaagggctgg 7800 gcagagcagg cgggtgggcc gcccctgggg ccttgttccg cagatcaacc tgatccgcac 7860 cctggggccg gggcttcctt tcacagcctt cccatgaact atggctcctg tttccatccc 7920 aaatcagatc ccagaagagg aataatgtcc atgtaaccca agccagttgg aagtgggtta 7980 catccaaccc ctgtcatctt ccagcttgtt aaggacttga ctaactcaac ccagagggat 8040 ttggagggtt gtctgcaaaa cccactaata acagggaact ttagctctgt agccacaggg 8100 tctacagagg tgtcgggctg tcgggttatt gctgggaggt gagccggtgg cgtagacacc 8160 atggaggcac cggtagtgga agagctgcaa gtgcacacag aggccggcac cgaggggcgg 8220 ggaggaggag gtggtggatt tctcgccagt gttggcatca tgttgcctcc agcatcagag 8280 acccaaggtg tggctgacct tggctggggc gatgagtcat tggatagcag agccttcctg 8340 gtagctgggg gttaacgctt taactgccgg gactttgtat tatgccgctt cttttttttg 8400 ttttgtttgg tttggtttgg tttggttttt gagacggagt ctcactctgt cacccaggct 8460 ggagtgtggt ggctcaatct tggctcactg caacctctgc ctcctgggtt caagcaattc 8520 tcctgcctca gcctcctgaa tagctgggat tacaggcacg cgccaccatg cctggctaat 8580 ttttgtattt ttagtagaga tggggtttcg ccatgttggc cgggttggtt tcaaactcct 8640 gacctcaggt gatccacctg ccccggcctc ccaaagtgct gggattacag gcatgagcta 8700 ccgcgcccag cttgcattta tgcttttttt tttttttttt tgagatggag tttcgctctt 8760 gttgcccagg ctggagtgca aaggcgcgat ctcagctcac tgcaacctcc acctcccggg 8820 ttcaagcgat tctcttgcct cagcctccca agtagctggg attacaggcc tgcgtcacca 8880 tgcccggcta attttgtatt tttagtacag acggggtgtc cccatgttgg tcaggctggt 8940 ctcgaactcc cgacctcagg tgatccgccc gccttggcct cccaaagtgc tgggattaca 9000 ggcgtgagcc accgcacccg gcctatgctt tttattatta ttatttaatt ttttaaggaa 9060 agcaatctaa actgtacact gtatcttttc tttctctttt gctttttgtt gtcagttttc 9120 tgtattactt attgccaaac aacatgaaca ggaaattgaa aggaaaactt caacaatcat 9180 tggctgtagc atttcttctg tgttccattc agtgcttgtc tcctcaggaa catgacatag 9240 ggtttgattt aattatgaaa ggcgtatatt ttcagagttt tatactcccc atagaatgaa 9300 tgttgaattc tgttcttttc acttgaaatt agatctcagg catggatttc atgattatca 9360 ctataatggc tcttcagagt ggacattgca tcttgtaggg aaccaccctc tccccagctg 9420 ctggtgtgga cgctcctcct tgatggtgtg ggtctgggcc cctgaagggt ggtgtcctga 9480 gtaaagatgt tacagtagcc atgcttatag ctttgggcct ggggctaggt ggagactggc 9540 ttcaacccta gagcttgctg tcttaaaata aattcttttt tttttttttt tgagatggag 9600 tctcgctctg ttgcccaggc tggagtgcag tggcgcgatc tccgctcact gcaagctccg 9660 cctcccgggt tcacaccatt ctcctgcctc agcatcccgc atagctggga ctacaggcac 9720 ccgcccccac gcccggctaa ttttttgtat ttttttagta gaggcggggt ttcaccatgt 9780 tagccaggat ggtctcaatc ttctgacctc gtgatccact cgcctcagcc tccaaagtgc 9840 tgggataaaa taaattctta gggccgggag cggtggctca cacctgtaat cccagcactt 9900 tgagaggccg aggcgggcag atcacaaggt cagaagatcg agaccatggt gaaaccccgt 9960 ctctactaaa aatacaaaaa attagctggg tgcagtggcg ggcgcctgta gtcccagcta 10020 ctcgggaggc tgaggcagga gaatggcatg aacccggaag gcggagcttg cagtgagccg 10080 agattgcgcc agtgcactcc agcctgggcg acagagtgag accctgtctc ataaataaat 10140 aaataaataa ataaataaat aaattcttat acccacttgc attatttatt attattatta 10200 ttaaacaggg tcttgctgtg ttgcccaggt tggagtgcag tggcgtgatc atgacctccc 10260 agtctcgacc tcccagtttc aattggtcct cccttctcag cctcctgagt agctgggact 10320 acaggtgtgc gctgcatgcc tggctaattt tttttttttt tttttttttg agacagagtc 10380 ttactctgtt gcccaggctg gagtgccgtg gtgcaatctc ggctcactgc aacccccggc 10440 tcctggatta aagcaattct cctgcctcag cctcctgaat agctgcgatt acaggcatgt 10500 gccgccacac ctggctaatt tttgtatttt tagtagggac ggggtttcac catgttggtc 10560 aggctggtct caaactcctg acctcgtgat ccacctgcct tggcctccca aagtgctggg 10620 attacaggtg ggagccaccg cgcctggcat gcctggctaa tttttaaaaa atttttgtag 10680 cagccgggcg cggtggctca tgcctgtaat cctagcactt tgggaggcca aggaggtcgg 10740 gagttcgaga ccagcctgac caacatggag aaaccctgtc tctactaaaa ctacaaaatt 10800 agctgggcat ggtggcacat gcctgtaatc ccagctactc aggaggctga ggcaggagaa 10860 ttgcttgaat ctaggaggcg ggggttgcag tgagctgaga tcgtgccacg gcactccagc 10920 ctgggcaaag agagtgaaac tccgtctcaa aaaatttttg tttttgtttt tgtagcgaca 10980 gggtcttgtt ttgttgttgc ctaggctggt actgaatttc cagcctcaag cgatcctcct 11040 gcctcagcct cccaaagcgc tgggagtaca ggcgtgagtc actgtgcctg gcctccactt 11100 gctttggctg cctttctctg tcttaggtaa ccatacattt ctccaggtaa ttaagaaaag 11160 attgcgcatg atgagtccct tttctggtat ttctgggatt gcccccaaaa ccagacaagt 11220 gttcttacct tgacatttta ttaagacttt aatgaacaga atgccgtttg ccctcagtct 11280 gctggtcccc ctgcgaaggc ccagggcttc cttgtttgaa aagtcatccc cttgtcgagg 11340 tctttgattc cttttcacca cggcagtcat gccgagggtc cacagagcca ccccttcccc 11400 atctcttcct cggcccctca agacgcatct gtacccccgg agatgtctct ttgttttctt 11460 gggccacctc tcctggccgt cactcaccct gctgactcat tacttgtgca acagtttctt 11520 ctggaaccct caggctcctg ccacctaccc tctgcagtcc ccgttttgtt cctcttgcct 11580 cagtcttcct ccccatcacc cctctacctg ttggtctcca tctctgtcta tggcacatcc 11640 ctgtgttata ctctgatggc tggataaagg ttgagtgaaa cgcatctacc cctttggtga 11700 ctggggtgcc cattaatcag aagggatcca aggctggcgt agccttttcc cgcatcctgg 11760 ggtatcgtcc tgtggctctt ccttgttgga gtctgcagtt ttttgttttt ttttttttaa 11820 attttttgag atggagtctc gctctgtcgc ccaggctgga gtgcagtggt gagatcccag 11880 ctcactgcaa cctccgcctc ccgggttcaa ccaattctcc tgcttcagcc tcccaagtag 11940 ctgggactac aggcgcccgc caccatgcct ggccaatttt ggtattttta gtagagacgg 12000 ggtttcccta cattggccgg gctggtctcg aactcttgac ctcaggtgat aggctcgcgt 12060 cggcctccca aagtgctgag attacgggca tgagccacca ggcccggccg ttgagattac 12120 cttcataagc caccaggcct ggctgtagtt ggcagttttt gaccactggt ctcgctccac 12180 gtgatctgtg atcttcccct tggccccctg gccctgccct gttcatctgc tcacctttct 12240 catgcatgcg gtttgttcat agggtatgta atggggtcta accaggaaat ggaaaccgct 12300 tgagcattta tttatttatt tatttattta tttatttatt tatttttccc aagacaaggt 12360 ctcactctgt cacgcaagct gaagtgcagt ggtgtgatca cagctcatgg cagccttgaa 12420 ctcctgagct caagcgatcc tcccttctca gcctcccaag tagctcggac tataggtgca 12480 cactatatgc ctgcctaatt ttttctttta tttttgtaga gacagggtct tgctttgttg 12540 cccaggctgg tcctgaactc ccaacctcaa gcaatcctcc tgcctcagcc tcccaaagta 12600 ctggagctac aggcatgtgc catcacgcct tgctaatttt tgtatttttt gtgtgtgtgt 12660 aaagacaagg tcttactatg ttgcccaggt tggtcttgta ctcctgggtt tatgtgatcc 12720 tcctgcctgg gcctcccaaa gtgctgggat tacaggcggg agccacagtg cctggtccac 12780 ttgagcattt agaacagaag gacttaaagg cggggaacta gttacacaga tgatgggaga 12840 ggtgaaggcc agacagggaa cagagaggca atcagcagga aatcaaagtg gtgtgggctt 12900 atacagccct ctaaaggtat ggatgcaatg attcatttag aatgagaaaa taaataacag 12960 caaattataa attataagca gctgttaaat atcacaaaca tcactacatg cagaagagta 13020 ccagtcaact gtcagtcata tctccaaagt tctatttctc ccacattttt ggcattactt 13080 cttcaatatg atgactttgt aatatcgttt tctatttcga gaacagaaaa ctgatcaggc 13140 tggacacagt ggctcgtgcc tgtaatccca gcactttggg aggccaaggc aggtggatca 13200 cttgaggcca ggagttcaag accggtccgg gcagcgtggc gaaaccccgt ctctactaaa 13260 aatacaaaaa ctagcagggc atggtggcat acacctgtag tcccagttac ttaggaggct 13320 gaggtgggag gattgcttga gcccaggagg tcgaggctgc agtgagccgt gatcatgcca 13380 ctgcactcca gcctgggtga gagagtgaga ccatgtctca aaaaaaaaaa aaaaacaaca 13440 aaaaaaaaca taggctgggc gtggtggctc acgcctgtaa ttccagcact gtgggaggtt 13500 gagatgggcg gatcacttga ggtcaggagt ttgaaaccag cctggtcaac atggtgaaac 13560 cccatctcta ccaaaaacat aaaaaattag ccaggtgtga tgacgcacgc ctgtaatccc 13620 agctacttgg gaggctgagg caggagaatg gcttgaaccc aggaggcaga ggttgcagtg 13680 ggccaagatc gtgccattgc actccagcct gggcaacaga gtgagactcc atctcaaaaa 13740 taaataaata aataaagcga atgaatctcc ttagttgatc aaattttgtt tttatttttg 13800 gtagttggga tgtatacaaa agtggcggtc aacatggagt tggtggtgct gctacaattg 13860 ttttgttcaa gatacacagg aattctggta aatcctgttt ttttcttttt ttttaaatgt 13920 gattcccatc aagaaagaag taggaaaatg ggggagattt ctaactgcat atgaggcatt 13980 tgtgcatgta tttctgacca gagagacttt tctgttttga ctccacattg aaggaactga 14040 atcctttgct tacaacttca cctctggtga tgggagtaat tttccacaga tttgcttctg 14100 gacccgtgca tttcaaatct tgcttctctc cactgcgcac gtttttccgg cgccaggcac 14160 cgcaggatat gttcgtgtct tgtgattttt gattctgcgc ggtaggtgga attggaacgg 14220 tgagtggagc gagtattgct ggaatccgtt tccacaccgg gatagcgagc agtaactgaa 14280 ctatacatgg aaataaatgg gaactacata aatataaccc gaccaaagcc aaactaaata 14340 tctttccagt tcaacttctc cttagcagga gcccccacgt ggcagcaagc ctccgtttcc 14400 acctcacaca agagaaaatg tgacgggcag gaactcaaga ctggaaatga acggggacgt 14460 taattgattg tagggaaaat attttccatt ttgtaaattt tacaaaaaat gtttgaccct 14520 gtggacatgt ggttagggcc cttctcagtg ccttgagagg gaaccatgca ggtagaggga 14580 gggttcttag cattgtgggg gtgacctgga gattggcagc agggtgccac caccacccct 14640 aggtggggat gagagggagg aagtcctgtg accagagtcc aggggccaga gtcacctgct 14700 gggagcccaa acaaaggtgg gactctggca ggagctggaa ctacacagag gaccacctct 14760 cctgctggag aagctgtctg aggcagagga ggtggagagc tcccgcgccc tcccttgctt 14820 ccacctccca ggttcctccc aagcctctcg ttggttgaac ccagcccaaa gccagcaggc 14880 ctggggacct ggacacctga gccagcagag gtcggcgttt ctcccacaca aaggagggca 14940 caagaagtgg gaggcacgga gggggatcag gccaggaccc acacaggatg tgcaaacagg 15000 agctcccctc tcttcccacc ccaaatggca tctgcagccg gcctcacttc cctgctgtta 15060 gacaggaaga ggaaccttgt tcccggcacc agctgccccc accgcccccc accccacgga 15120 ggcccctttc ctctctggcc tttgcttgca atcattggcg acgctgatgg accatatctt 15180 ctggggagtt tggtcatgaa catggtttcc catttgttgt ggaccaaact gtgcccttcc 15240 ccttgaattc ctgcgttgaa gccctaactc ccaatgcagc tgtaattgaa gatagggctt 15300 ttagggaggt aattaaggtt aaatgaagtc atagggcagg accctaatct aataggattg 15360 atgtccttat aagaagaggg agagacacca gagatctctc ctcccccctc acttgtaaac 15420 agaggaaaaa tgacggagga cacagcaggg aggtgggtac aagccaggaa gaggggcctc 15480 gccgggaact aaccctgacg gcaccttgat ccgggacttt gggcctctca aactgagaaa 15540 tacatgtctg ttgtttaagt cactccctcc acagtaatct ggatggcagc ctgagcttac 15600 caaggcaccg tctgcatcag ccagggctct ccagggagac agccaatagg agatggatgg 15660 atggatggat ggctagatag acagacaagc ggacagagag agagagagac aggcagacac 15720 agacagacag gcagacaaat ggctagatag acaagcagac agagagatag agacagacag 15780 acacaaacag gcaaacagac aggcagacaa atggatagat agatgataga tagccaggca 15840 ggcagataga cacagacagg cagacagaca gacagacaga tgataggttg ggttcagtga 15900 ctcttacctg taataaccag cacattggta ggctgaggcc ggtggatcac ttgaggccag 15960 gagtttgaga ccagcctggc taacagggtg aaaccccatc tctactaaaa atagaaaaat 16020 tagctgggcg tggtggtgca tgtctgtaat cccagccact cgggaggctg aggcacgaga 16080 atcacttgaa cctgggaggt ggaggttgca gtgagctgag atcacgccac tgcactccag 16140 cctaggcgac aaagtgagac tccatctcaa aaagaaaaaa aagatagata gatgaatgga 16200 tagatagcta gatagatgac agatggatga taggtagata gataattgat aaatagatat 16260 aaatgaccga tggacaggca gacatagata cattgattag gtagatgata gatggataga 16320 tagaagatag atggtggatg ggtgggtaga taggcagata gacagttaga aagatagatg 16380 atagatagat aggaaggaat ttattagggg aattggctca taccattgtg gaggccaaga 16440 tgtaccacag aaggccgtcc gcaagctgga ggcccaggaa agccagtatc gtggctcagt 16500 ccaagtctgc aggcctcagg actgggaagc tgttgatgta actcttagtt taaggccaaa 16560 ggtttgagag cctggggaac tgctggagaa ctgggagttc taagtccaag ggcaggagag 16620 gaaggcatcc cacctccagg agaaagaggg aattcacctt ttctctgcct ttttgttgtc 16680 tggcaatgga atggtgtcat ccatattgag ggaggatctt taccactcag cccaccaact 16740 cacatgccca tctcctccag aaacaccctc acagacacac ccagaagcga tgcgttacca 16800 gccatccctt aatccagcca aactgacacc tgccgtcagc caccacacag gctcagaaga 16860 atcgtggttg catggtgatg gtctccatcc cgtctaaaga agttgaagat gaactgttgg 16920 cacaagccat cgttctttca ggctccttcc agtcgttcat tcttttaaaa atgtattcat 16980 tgagcacctg ctgcatgcca ggtgctgtga caagcactgg ggcacagcag tgagcaaaca 17040 aggactcttg tttcttggag tttacatgca gtagaaggaa acagaatcaa tgaattcatc 17100 agttctagaa actatcaaaa taggactaag agctgtggtg agaattaaga taaggtgatt 17160 gcatagaaag tgactgatgg ctgctttgga atgagtggtg aggggtcaca gagatgatga 17220 cagctgagtt gagattggga agacaggaag gagccagcag tgcaaggact aggctggaag 17280 caagcttggt gcattccagg aacagcaagg aggccagagg ggctgcagta gagcaggcga 17340 ggaggaggag ggagacgcag gtcaaagagg agcctggggc cagatggagg accctccctc 17400 caaagctcag tcatttcctc cttaaaggag aatgtgttac ctccaaaagt cacatatgcc 17460 agcacagtgt ctggctcatc atatgccttc agtaggcggt gagcatggct gttcttgtta 17520 ttactacatc acaattacta ggaataatgg agtcaccagg ctttgcattt acagcaatgt 17580 gagggagtca gcaagcttcc ctggggaacc catctcccct cactaagttc ataagagcct 17640 gataaccagg tcaatgtagt gagagctata gctgcccagt gtactggact ctttagccac 17700 gggccaggac actttcatct cagcagaaac ctctaagggg actggggagt gtgctgtgga 17760 tgtttctggg ttactcagac ctcctgggga gccttcccca ccgcagctgc tgcagggagc 17820 tcagctgcag tgatgaactg cggctcagcc ttgtttatgg gaaaacccta catgggagat 17880 gggacggttt cctgttggtt ctctcggcct caggttgctt tcacaagtgc agggattctc 17940 acctgggtgt gtgaatgggg ctcaggatgc cccaagggta tgtggagatg ggggtcagct 18000 gtcttctctg atgcctctga acctcctccc cctgcctttc tgcatctcat tgcttcctgg 18060 cctctctcac tttgggtgct ttggaacaac atgcaatcca atacacaggc tgactttatt 18120 attttgtttt gttttatttt attttatttt ggaaacaaag gctctgtcat tcagcctgga 18180 gtgcagcggt gcaattgcaa ctcactgcag ccttgaactt ctgggctcaa gtgattctct 18240 cgcctcagcc tctcaaagtg ctgggattac aggcatgagc tgctgtgcct ggcctaggct 18300 ggctttaaaa gctcctcact ctctctgcat cctgatgata cctacctcct ggagcaggct 18360 cccagccatt ggcttcggat actttgtagc tattattggc cagttgtggc atgtgaagct 18420 gaggctcagg agaagggcag tcctgtccaa ggccacacgg ctcagtgcta acactcagac 18480 ttcagtgttt ttatctccct cctggtcgct tccaccctta gtgcatctct ggaggcccaa 18540 gggagctaaa ggccaggctt tggtcagcta agaatttaaa aaagctgtct ctgtgctcct 18600 ctgtcaatcc atcactccat tatctccccc gacaatgaat tcagtttgaa tttcagataa 18660 acaaggatta atttttagta taagcatatc ccacaacaga cttgggatat acttatgcct 18720 aaaaatgatt cattgtttgc tggccttagt agctcatgcc tacaatccca gtgctttggg 18780 aggctacagt tggagaattg cttgagtcca ggagttcaag gttacagtga gccatgatca 18840 tgccactgag ctccagcttg ggtgaagcag caagatcctt atctcttcaa aaaattgttg 18900 attgtttatc tgaaatccag gtttaactga gcatcctgta ttttatatga gaaccctata 18960 taggtgagac ccagagtccc aatgcccact ggtaagcctt tgcagggagg ctctgtgggt 19020 ccttggctgg cactgatgcc ctgtgatgag cagggccatc tggcaaggtg gacgcctgct 19080 gcccatgcag gcagagcaag gccctgggca ggtatgagct gatctcacct tccccagcct 19140 gggagccaga tactgttggc agcttgccgt caagagaggg gctggtcacc aagagagggg 19200 cggcctccat gggccttctt tggcttttgg ctctccccca gccctcctcc taccccaaac 19260 agaggccaac ggcaccgcac cagaaccagt gtgctgcctc ctttggttgg cattttgtag 19320 ttgggtagac tgtttccttc tcacaggagc tggtggtgcc ccttccgctt cacagggagg 19380 atggctgaga cccctgacct tgacacaggg tgctgttctt tttttgtttt gagacagagt 19440 cttggtcttt tcacccaggt tggagtgcag tggcatgatg ttggctcact gcagcctcca 19500 cctcctgggt tctagcaatt cttctgcctc agcctcctga gtagctgaga ttacaggcgt 19560 gcaccaccac tgagaacaat gccttctaca gtgtttattc tcctgtagga gcaagttcct 19620 aaggcaagga ggttgctccc ctcatggatg aataaattga ctttgatcca cagccccacg 19680 tgtcagcctt gagggtgggg aaaggttgtt ctgtgtctag gcagggggtg ggggcaaggc 19740 caggagggcc tggtgcccag tgtacctctt caggacacaa ctccaggtag cagaggccaa 19800 ggacagaggg gaggagaaga gggaggtggc cattatctcc ttatctcagc ttcctttgga 19860 gataagcttg agtattttag ttgtccacta agtctggaga taagtctgga atttaaacct 19920 ttgactttga tccagccctt cacagctcct gtgagcaaac tgagcctcag aaaaagggag 19980 tgaagcctgt gcatcctgga cgcccccacc ccaggctcaa accgccccca ccccaggctc 20040 aaaccgcccc catcccagct caaaccgccc ccatcccagg ctcaaagcgc ccccatccca 20100 gctcaaagcg cccccatccc aggctcaaag tgcccccatc ccaggctcaa agcgccccca 20160 ccccaggctc aaaccgcccc catcccagct caaaccgccc ccatcccagc tcaaaccacc 20220 cccaacacag gctcaaacca ccctcaaccc aggctcaaag cacccccacc ccaggctcaa 20280 agcatcccca ccccaggctc aaagtgcccg caacccaggc ttaaagcgcc cccaccccag 20340 ctcaaaccgc cctatcccag gctcaaaccg ctcccacccc aggctcaaac cacccccatc 20400 ctaggctcaa accgccccca ccccaggctc aaagtgggaa ggagccacag ggaaacaaac 20460 gggggaggca cggatgacca ggatgagggt ctccatgacc cacctttccc caggggctat 20520 ctcaagagct ttttaaactt ttattatttt ttaatagaga tggggtcttg ctgtgttgcc 20580 caggctgatc tccaactcct agcctcaagc catcctccca cctcagcctc ccaaactgct 20640 gaggttacag gtgtgagcca ctgcacctgg cctctctcag gagtttcaag aaaaaaaatg 20700 ggaatagatt tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgttttga 20760 gaaagagttt cgctctgtca cccaggctgg agtgcaatgg cacgatctcg gctcactgca 20820 acctccgcct ctcgggctca agtgcttctt ctgcctcagc ttcctgagta gctgggatta 20880 caaacatgca ggctgatttt gtattttcat tagagacggg gtttcaccat gttggtcagg 20940 ctgatctcga actccggacc tcagatgatt tgcctgcctt ggcctctcaa agtgctggga 21000 ttacaggcct gagccaccgt gcccggccag gaatagattc ttttctgtag atgacttctg 21060 tcattattga aaatggatgt ttatgcacaa ttgaattgtc ataacgcctc atcctaaaaa 21120 gctccttttt gagaaaatgt gacttttgat agaggagaga ctgtccaggc ctcattcatt 21180 gtcagcacaa aggcagagca ggggtgtggc ggtgtcaccc tcctctgaga cagccccatc 21240 cctgctctgc ccaggggttc agaagtctgg tctattcgag cccacagagg ggtttggagt 21300 ggctgtctta catcacaggt ggggtctgta aggatctgaa atgacctttg agaaggcggg 21360 tgtggtgggt gcatttcaat cattaaagta acaacaatga tacatcaaat agtgtctgct 21420 cagattctga gtgcctgttt aaacatttcc atcttgtgac ttgccagatt ctagcataac 21480 aacccaggta aaagaaaaaa tagctgggcg tggtggcttg tgcctgtaat cccagcgtga 21540 ggccaaggca ggaggattgc ttgagaccag gagtttgaga ccagcctggg ccacctgaga 21600 ccccacctct gaaaataaac aaaccaataa aagaccttca tgctctatgt ctttcttata 21660 tctaggttcc ccaaattata tgcattgggg aaagtccatt aagagaagcc cctggccggg 21720 cgtggtggct cacgtctgta atcccagcac tttgggaggc caaggtggga ggatcacaag 21780 gtcaggagtt cgagaccagc ctggccaaca tggtgaaacc ccatctctac taaaaataca 21840 aaaattagcc gggcgtggta gtgcatgctt gtaatcccag ctacgcagga ggttgaggca 21900 ggagaatcac ttgaacctgg gaggtagagg ttgcagtgag ccaagttggt gccactgcac 21960 tccagcctgg gcgacagaaa aagactccat ctctaaataa ataaataaag ggagagaagc 22020 ctctgggctc ctagatacat gggtcagtgt ccacccctgc aaagctgctg tgcccaaaga 22080 ggggctgtac ttggtggaat tggggcaaaa gagcagggag ggcactgggc agttgacctg 22140 gtctccacta ctggaaaggg gctgtgctgc tggtgccctg agctggttcc acaaggaaga 22200 cactgcacag ggcgccctaa gtttgctctt tctgcctagg ctcacccttt cctctccagg 22260 accagggagc cccgctcgtc tcctgtcttc ggcatctgct ctctggcttg tgagcactgc 22320 atttctttct gcttggaacg ccggcccatg gtgggtcccc ggactcctgc cttctgctgt 22380 cttttgccat atctcgtcaa agtgtgtttt atttatttat tgttattatt ttttgaaaca 22440 gagtcttgct ctgtcgccca ggctggagtg caatggtgtg atctcggctc actgcaacct 22500 ccgtctcctg ggttcaagcg attctcctgc cttggcctcc cgagtagctg ggattacagg 22560 cgaatgccac cacgcccggc taatttttgt atttttagta gagatggggt ttccctatgt 22620 tggtcaggct ggtctcgaac tgacctcggg tgactggccc acgtcagcct cccaaattgc 22680 tgggattaca ggcgtgagtc accatgcctg gccaactatt ataatattga tattataata 22740 atatcacagc cagataacgg tgactaacgc ctgtaatccg aacactttgg gaggctgagg 22800 caggcagatc acctgaggtc agttcgagac cagcctggcc aacgtggtga aaccctgtct 22860 ctaccgaata tacaaaaatt agccggagcg tgatggcagg tgcctgtaat ctcagctact 22920 tgggaggcgg aggttgcggt gaactgagat cgtgccactg cagtccaacc tgggtgacag 22980 agcaagactc catctcaaaa gtagtaataa taataataat aataataata tcacttattg 23040 agttttaatt ttgtgccagg cactgtgcta gtacttgcgc catgtgacct cattgactcg 23100 gaacaaccta tgagtaagca ccatctctgt ccccaaggaa gctgagactc aggaaatgga 23160 agtcatctcc cagggcccac agcaagggcc tggcgaggtc tgcgttcaaa ttctgatcat 23220 ctgactccag gctttcctgc ctcctttgcc tcccaaaaac tcaaatactt tcatctggga 23280 tgactccaga cagctagatt tcaattgtct tctctccttc tgagtatgtt ttattttaaa 23340 atcacataaa gataactcac ttctcaactg gagccacgga atcgttagat gtcttggaga 23400 cttttctagc tacctctttg ctggactcag acacaggcct gaataattag gtccaaggag 23460 ctgaactgga gccgctcgtg gccagaggtc ccttcctggg aacagcagtg gcggcagcgg 23520 ctgcgctgag cctggcaatt tgttcaagag caggggatgc tcaggctgcg ctcgccccct 23580 tcttatgaac ggtttgcttt gcgtcttctc tgtgccaagg gctgccaggc accagatgcc 23640 cattttagga aatcagaaaa ataaacagtg taaataaaac aaaaactcca cccaagaaat 23700 ctgagacaga tgctgttttc cccaccgttt ctccaccccc atgctgggtt tggagagagt 23760 gggccagcat gtttcctacg gataagaggc cctggggtat ttaacctgga tggaacctct 23820 tctattttcc ttttgcctgg tgctaggggg cagaaggcag gggtggtgtc catctggccc 23880 agggaggagg atagggcagc ctttgtcgcc ggcatcccct gcagagatgt ctcagccaga 23940 agtgactcca tcctcaggaa cgtgtgtcct gttctttgct gggcggcccc tccttacccc 24000 ccattgtttc cacagtgggg tgtgctagat ttatgggcag agttctggtt cactctcagc 24060 cccggacagc agaatgtccc agtagtgcac tgatggtgtg tgcgtgggga tgtgtggaac 24120 aggggatagt gaccccgtgt gcgttatatg cagtgcggct tccagtcggg tgtgtgaagg 24180 gggtgctcat ggccatcgtg gaagtgagct cagctggggc tggagggtcc aggctcactg 24240 tatgccactc agcagccttg ggagtggggt tcatcctcct ccccgctcct ctcccctcct 24300 ggtcctgggc agcccaccgg agctgcactc tgggccatct ctcctggtct taaggaggct 24360 gtcatttctg ggaggcagat gctggccctt ccatccttgc ttcctggaga tctgcgccga 24420 ggtctgcctt tctgtctgga gggactggcc aggaacccct gggttttcct ggtggggttt 24480 ttgttgctta gcagtgagca gagtgagtgg gcaccaagag gaggatgctg ggtgaggtca 24540 cggacatggc tggggcaggc tgggggtgct ggaggtgaat tccgcagctg tgcgaccttg 24600 ggcagtttgc ccagccctgg gcctcgcttc ctcctctatg aaatggggcg ggagcacctg 24660 cctgctgggg ttgtgggttg ggtgaatcgg agctaaggta cagctcacag cctgccgtca 24720 gaccctcgca agcagaagtg ggtgtccctg ctcagcgtcc tccggtccct ccttcaaggc 24780 tcagctttgt cctcatctcc tccatgaagc ctccctggtt actccaggag tcacgaccca 24840 caccctcttt ggagccttgt gtcacacgca tttctcacgg tgttgctttc cctggaggat 24900 gggttcaact aaaattgggg cccatctggg ggttccctcc agcaccagag aagctcaggc 24960 ttagtagaga tgggtaccct gtcaatacta gttccgcgaa ggatacactg tgctcattct 25020 gctgccagtt gctgagtctg gtgtcctgta gttatggaac atgtgtacag gcctgggctg 25080 ctggacacga aggccagatg ggcagttcac tctgcctccg ctctgagcct ttagaaacaa 25140 gctggctgca cccatttcca tctggtcaca gtttaggagt ggggttgtgg aatggatgga 25200 aggaaggatg agtgggtggg tgggggggtg ggtgggtggg tggatggatg gatggatgat 25260 gggtggatgg gttgatggat gggtggatta ggtggacagg tgaatggatt ggtgggtggg 25320 tgggtgggtg aagggctgaa taggtgggtt gggtggatgg gtggatggat gtgtggaggg 25380 gtggtggggt ggatggggtc catgggtgaa tggatggatg gatgggtgaa tggagtaaat 25440 gagtgggtgg atggatggat ggatgctgca agagcctttc tggagggttc cagggaggaa 25500 ctggcatctt tgaccagcag ccagcatggt gatcagatac agggaggtgt ctgggtctgc 25560 ctgatccctt atctcactgt tggtgggact gggctggtta tgtgtccctg aagctctctg 25620 aagggtggct gtatggcatt gcccagggga catccccaga gtgccgtgct ctacagcaat 25680 agggtggccg cctgtgctcc cagggccgct cctcctggca gcctttcggg tttgcttggc 25740 ttagcacctc agcaaatctc ctcgagttag gacttgcctg ccatgagcct ctccaacaag 25800 cagccccagg ccaaggcctg tgtgtgggca gagggagcgc atgccgcggg aggctgcatt 25860 aatctgaggt tctgtttttg ttccctcctg gggcaaaagg taaaaatagc ctgtcccact 25920 ccatccccaa atccagcccg gctgcaccca gccctgggag tgaagggggc tgggtcagga 25980 ctgcccgtga gttgtagacc ctggtgtagg gaaaccctga ttcataagac gggtggacat 26040 ggaggaagga ggagactccg tccagcagag acacgcttgg gtgcagccca gcttggagtc 26100 tgatggacgt gggctcacct gtgtgcaact ctcattcact gtgtggccac agggaagtga 26160 cactctgtgg agactcagat tccttatctg caaaacaggg gtagtagggc ttgggggagg 26220 atgtgtgtga aggtttggcc cagggcccct ccagcagcca gacagcagtg gctgtcatcc 26280 ctccagcgtc cagggttacc tgggggagta gggcctctgt ccccagatgg gccccgtttc 26340 tggctctgga actcacagca ggagcaaagg cgaggacatt cctggtgtta atcatccacc 26400 cggagggaga gcgccagtgg ccttgtgtga cctttgccct ttgtctctgt ctttaggagg 26460 cacgcggacc tccagtggcc ggctccggag gcttggtgac tccagtggcc caggtaggtg 26520 gctcgctccg ctctggcccc acccagctca tgggtgtgtt tgtgctgggg tcccttcatt 26580 ctggtctggg acctgcctcc ccacctggct tccctggatg agtggggcca cttgcccatt 26640 tcccagggag acgcagtctt tgacggcttt ggactcaggt ggcttccagg cctgtcgacg 26700 ctgccctgct ggagatgatc cttgtggggg caggggcagc cacccccagg ctcagggagc 26760 aagcccgtgt gtgcgggaca gaggagagaa caggagatag atagggctgg atgatttggt 26820 ttgagatgct gaggggacag atgtgccatg gacaggtggc tttggccgtg agcctctcgg 26880 tgttggttca gtatctgtgg gctccctgca accttgcagg atggaagatg ctccaggata 26940 gagcagatac gtccggtgtt atctaggagg aaataagtgg gcctctggca gtggtcactg 27000 tgctactcct tgtgcttttt ccatgtgttt ggaaattttc cacactaacc agtagggaag 27060 ggaaacagat gcacccatca gagctctggg gctggccgtc caggacacga gttacagctt 27120 ataggcttga agggactcta ccaacactgg gtgcagcctg ggcaagggag tgggacagag 27180 aggtcagggc tctgcctcca gcccttgccc cccagggctg agtctgcgcg tcatcttctc 27240 cccactgggt gtccctgatc tcccctgcct gaccccagtg tggccatgct agtgcctctg 27300 tttctgggag cctacgttgt tcttggctgt cacttccagc ggccaggctg ggacaggtgc 27360 ccatctagtg gcttttctat ttggagagga tgatgggtca cagcaatgaa tggacttacc 27420 tcccctagga gacgaggagc tctgagaaga gcagagatgg cgtggtcacc tgtgcatatg 27480 tgctgggggc caactgggtg ccagacccct ggctgccatc atggtggcag acaggcaggg 27540 actgtgcctt catgaattag ccattctaga ggagacaaag ttaccaaagg acacggaccc 27600 ggagtcaaat ccacacaaat agagcgcctg tggaccaggg ctgccttcag aacaaggtga 27660 gacagccgtc ctgccaggac aaggcgccta cgggggcaag ggcatgtgcc catctggagc 27720 cgccacctcc atgctctaga ccagctccgt ctaatagaac cttctgtgat ggtgggtctg 27780 ttctatacat ctgcactccg ccatcctgta tggtagccgc ttagccgcct gggtctattg 27840 cacactcaaa gtataaatgt ttacgtttac tttattcact catttacttg catagaatta 27900 tttatttatt ttaaatggat ttccacttat atctacgtgt ggctagtggc tatgaaactg 27960 aacagttcca gaccacactg gcacctgaga cctcagaatt ctagacccaa agcctgcttc 28020 tgatcctgag cttgcttctg tggggacagc acagacgcct cctaagtctg ccttccagag 28080 gtggatgcag tgcccgtgga ctgtgcacca ccaggcctgg acagtggaga gggtggcttt 28140 ttacagggag tgggagtgga ggggatgccg tgtccacatt gagtgcatgt gaggcccctt 28200 gcagtacagg atgggactgt atgtgggaag aggggggtga tgctctggct ggaggcccct 28260 gggcagctgc atgattcagc gctgtggtta agaggggctc cgcccatcgc agtcatgttg 28320 ggcactaacc actggacagc ccagccgctg ctgtgtttct ggggagcttt tctccggctc 28380 cgcatctgat ctgcctctcc atctccttcc ctctcattgg ccagcttctg gtggaatggg 28440 tggggagggt cccccagttc ttgtgggggt tgcatcttgg gaacctggca ccctgggctg 28500 catggacaca gcctcccccg gcggttgctt ccctctgctc agactggctg gttctgtgct 28560 gtcagcactt ggcagccacg atcacagctc agcttggaag cctaaggcat aatttgctga 28620 atcccaaagc tgcaagctgg tgatctgggt ttgcgtggga ctgcctgctg acacacgggg 28680 tcctccctct gtgggcctct gtgggctctg gcccgagaca ccctttcctc atcttcttgg 28740 cttctttctt tctccctgcc tcccttttgc taagaccctg gtccaggcag gagttcattc 28800 ctagacgccc cagcatctcc ggcctcccca tttgacactc cccagacgac tgtctgccat 28860 cccatcctcc cagcccagct tctctgtaga tccacatctg gccaatctcc tatgtctggg 28920 actcttgccc tccccagaag gacgaaggct cttctcgagg ttgtgtttgg gactgggcca 28980 gggatgacat ttctggcaaa agcttaaatg acaccatgat caacgctttg gtcagctcac 29040 acactttctt tccttttaaa aaaaaaatgg aattcttaga gctacaaaac aaaaatgtaa 29100 agaataaggt aataaaacac ctgtgtactc accatcccgc ttaagaagtg agacattgca 29160 ggtgtagccg cagccctggg tgaccttctc catcctagcc ccactcctgc tgcggtgccc 29220 gcccctctgg attgggatct ggccccgggc aggcacatct gtgctgggca gtggtgtgtc 29280 tgagaagcct aggtctcctt tttttttttt ttgagataga gtctcgctct atcgcccagg 29340 ctggagtgca gtggcaccat ctcggctcac tgcaacctct gcctcctggg ttcaagcgat 29400 tcttctgcct cagcctcctc agtagccagg attacaggca cccgccacca tgtctggcta 29460 attttttttg tatttttagt agacacaggg tttcaccatg ttggtcaggc tggtctcata 29520 cccctgacct caggtgatcc acctgccttg gcctcccaaa gtgctgggat tataggtgtg 29580 agccaccgca tccggcctgg tctcctcttg catacggtca tcagcatcgt gtgactgagc 29640 agcctaggtc tgtctcctct tgaatgccgt catcagcatc acatccttgg tgcctcactg 29700 gagtcagtgg ctgccctgcc tgtgcccaca acgtgacggc gtggagactt atccgtgtag 29760 atccacgaag ccttggttca cttattttgg cagctagcga gtgttcctct gtgtggggag 29820 gcagagtttg cccgtcccgt ggcccactgg tgacatcgcc gaaggtcttc tctgttacta 29880 gtgctgccgg gaacgtgtgt ttccccaggt ggatttggct gggctgtgga gatgcgcttc 29940 tcagcccttc tagatgttac caccacgccc tcccgagtgg ccttctggta ggctctccca 30000 tgttcgctca ttttctgtgc ctcaggcagc cgcctctctg actgagcgtc cagcggactt 30060 ttgccctgtt tcccacggtg cacggagcat ttcatctcag tggtgcctga gcttccctcc 30120 ctctggccct cagaccccgg ctgggatcct tggagccaac tcctctgcct gacatcccgt 30180 gtcgctaggt cctgctcttc catcttccaa tacctctggg gtgtgtggcc ttttccccag 30240 tgcccccatc atcccttctg tcctaggttg aaccgtgtcc cccacaaact catgtccacc 30300 aaaaacctca gaatgtgacc tgggagttgg agatggggtc tttgcagatg taagtagtta 30360 aggatcttga gatgaggtca ttctggatta gggtgggccc taaatccaac aactggtgtc 30420 cttaaaagaa gcagagaggc cacagacaca ccggggagag ccacgtgaag gcaggagcag 30480 atgatggagt gacgcagccc caggccaggg agcgtctggg aagaggcaag gaaggacccc 30540 ccccccaccc caccccagag cctccctagg gagtgtggcc ttgctgacac cttgattttg 30600 gacctctggc ctccagcatg ggagagaacc cgcttccatt ttttcaagcc ccacagctgt 30660 ggtccattat ggcagccaca ggacactgat gcacctccca cctggccgct gtggatggac 30720 gaccccgccc gcaggaagtc tccctcaagc actgcaggtg tctctgccct cacaggggac 30780 gcctgcacaa gtaggtgtga aaaaagggcc ctgtgggggc aaggcctggg ctggtgctcg 30840 ctgcctccct tcatcctatg ctagttccca tgcctcttcc ggcaggagtg cctggctcca 30900 cctggtgaat cagagccaaa ctctcctgac aattggctgt cacttattta actgccacca 30960 tccccaggag acagaaaatg ccagaagggt ggggcctgtg cagtgcctcc tcgctatttc 31020 cccagggcac cgtgccacgt tgcctcaatg cacagagtag ctgctcaaag tgtgtcggac 31080 gaacaggtgc cccatgccca gccatgcaga caaaagtgtg ccacgtggag ggagctggtc 31140 gtggaagaga ccaccagcat cttggctgcc cgaggacctt gcccctgggc tcttgcaggc 31200 acccctagtt cattacttcc tctctcaccc atagctaccc actcttcctc tatttctctg 31260 atatcagcct tgccacccac ccaggtttgc aagcaggaaa tctcagagtt gaccttgacc 31320 tctgcctccc cagcaccccc aggtctcaac aggctgccaa gatctcatca actcgccctc 31380 tgcatactga cccttggaca ggctgccccg gtcacggtca tgtcttggtt gggcctccat 31440 catccctcct tggaccagca ggtgccatcc tccccacccc tgccctgctg tggctccttc 31500 ccctccacgg ccaacattta gaggacgatt accacttccc tccctgtgtg ctggggaccg 31560 ggtgatagga tccctccacc cgatcatttc cattagacct gggccgggtc ttcttactca 31620 tagagccctt agtttccgcc cccaaagcct cgagggtgga ttcgtgctgc cgcccagcct 31680 ggccctgata ccgctttcca gcctggagcc ccctgcttct gcgctcctgg ctctgagtgc 31740 tcgggccccc cctggatggg ttgccacttg tcctctggaa agcagggctt ccatgctcct 31800 ggacctccta gctgactcag tgactttggg ccatcttgtc acaccccttc tatcagcttg 31860 gccttggtta tttctgtgtc ctccatagcc tcggaccaga gccacggcgg gatgctttcc 31920 tggtgcgtgg caggcagtca ggaaatattg ctggactgac cttgatagga gatgcttggg 31980 agaattgccc aaaaaactag cttaaaatgc aaatattggc cttcttttgc gttggctaaa 32040 gagtagcatt tctccgtttg cctcccgggt aagaaattga tggcgaatgc aatgtctcta 32100 gggaggagaa gaaggtgaca aaaagggtct gtataacggg gcacacgcta ggcatttgtg 32160 actatttaag tttaaattat aacataaatg cgaaactctt tgccttggta gcccttccac 32220 attgcaagcg ttcactgcca catgtggctg ccatattgac tacggcagat acagaacatt 32280 gacatcattg cggagagttc tatggggggg cgctggttta gatcatcttc acgttggatc 32340 cacaaattca ttgtttatcc agtgaacggt tactgggcac ctactgagca agcaggatga 32400 aagacacccg ctctcggggg agtcttccgt tggctgcaga gaagcttaaa ctcaggggac 32460 ctggggcaaa ctctgcaagg gcccttggcc tctgcacccc cagacctccc tcgctctgca 32520 ggggcagtcg ggggccccct ctaggaatgg agcgccagct ccagctcctg tcaggctaca 32580 gcccagatgg ttggctgagc acgagcatgt gagagtggaa ttgggcccaa ccgggctgct 32640 tctccccgtt gtcttggttt ccttccacgc tgacctggaa ggactcctaa agcaacaggc 32700 ctgcccaggc ggtttgcacc agtaaaccct gcagcggccc caagggcaga gatagctgga 32760 ttgtatttat ttaggaacag ccaaagtctg aggcacaata aaaagtggag aaagattcca 32820 gagaggaatg cagctggcct cagcctggga atccgtcttg cttgggaggc tgtaggcggg 32880 ccaggctggg gccagcctgg agggtcttgg ctggctctgc tggcaggtac agtagcaggg 32940 tcagcaggag ggagtccagg acggagctcc ttcattttta attcagggaa gcaaacttca 33000 gtggttgagt ctgaggatga gcaggaaatg aatggaaaag tctttttttt ttcttttttc 33060 tttctaggca gggtctttct ctgtccccca ggctggagtg cagtggcaca attatagctc 33120 actgcagcct caacctgcca ggctcaaggg atcctcctgc cttagcctcc taagtagctg 33180 ggactacagt tgtgcgccac catgactggc taattcttaa aagaaatgtt ttcaggctag 33240 gcatggtgac ccatgcctgt aatcccagta cttttggagc cgaggtggga ggatcacttg 33300 agctcaggtg ctccagacca gcctgggcaa catgacgaga ccccgtcttg actaaaaata 33360 caaaaagtta gctgggcgtg gtggtacagc cctgtagttc cagctacccg ggaagctgag 33420 gctgcagtga gttgtgatca cgtcactgtc ctccagcctg ggcaaaggga gtaaggccct 33480 gtttcaaaaa aaaaaatttt tttttttttt gaggtggagt cttgctctgt tgcccaggct 33540 ggagtgcagt ggcatgatct tggctcactg caatctctgc ctcccaggtt caagtgattc 33600 tcctgcctca gcctcccaag tagctgggat tacaggcatg agccactgtg cctggacttt 33660 tttttttttt tttttttttt gtagagatgg gatttctcta tgttgcccag gctggtcttg 33720 aactcttggc ctcaagtgat cctcccactt tggcctccca aagtgttgga attacaggtg 33780 tgagccacca cacccagcag gaaaagtcac tttttaaagc gagaggttgt gcgtcctcta 33840 tagcttggcg ctcatcagca tggaggattt actggaacgt gtgttaggtg aggggacatg 33900 gaagatggca gcaaatccga gcccagagca tcagaaagca tgctttcagc caaagatgcg 33960 ttctctccac ctccgcgcag cacccttccc cagtgtgtac tcctggagca aggtggggcc 34020 gatcctacga agaccctttc ccgaaggccc ctgctgccca catcagtgtc acctggaccg 34080 cctgctccct tttctggatg gctggaccag ccccagggcc tcctggcctg gtgtggggag 34140 cacagtccac cctggggaat gcctggtatg tgtcccctcc ccactgggta ccaggggatg 34200 aagctgtgct tcgtggaagg ggacagaggc gctggtgccc aggatggtgc acctggggcg 34260 gctgaactgg acctggctcc tactgggccc ctgtggagcc cagattgttg tgagaagggg 34320 tggggaaagg caggtgatcc gcacctttca cttttgtttc acatgggaac aggggcttat 34380 cctgcacaca tattcagttt ggagtatgaa tttccatgaa gaggaaaatc tctattaggc 34440 tctgatgtca ggattgtccg tgagggccgg gccgtgttct ggggcaagga caggagtgga 34500 gggggcaacc agggaaggct tcctaatgga ggaggcattt gatagcatct tgaaaaagaa 34560 gcagttccta ggccaagcca gagactgaag aatgaccacc taacttcttt tttttttttt 34620 tgagatggaa tctcgcgctg tcgcccaggc tggagtgcag tggcgtgatc taggctcact 34680 gcaacctcca cctcccaggt tcaagcaatt ctcctgcctc agccttctga atagctggga 34740 ttacaggcat gcgccaccat gcccagctaa tttttgtatt tttagtagag acggggtttc 34800 accatgttgg tcaggctggt ctggaacccc tgaccttgtg atccacctgc ctcggcctcc 34860 caaagtgctg ggattacagg catgagccac tgcacccggc cacgaccacc taacttcttt 34920 ctacaagatg ccccctggct gacgcaaagc aggttgagtg agtgtgacac ttccttcctg 34980 tctgtgggtt ccggcctttc cagagcccgg ccagtgctat tggagacaaa gtggccttcg 35040 ctcttccttc ccgccctgcc aggcccagcc tgtgccgctg agccccactt tgcaattaag 35100 aggagctgtg aaccagtgat gctgatgtcg cagaaaagtg gccaggggtc tatggggggt 35160 gaaggacagg gatgccgccc tgagaactgt ctggaagggg cttttgggta acagtgccca 35220 ctccagggtg tgggcaggct ggggtggctg ggagctgggc tcataggctg gcacaaccag 35280 agtttcccaa agccgtgggc ctgagggccc tgccttcctg ggacagcaac ctttggtcca 35340 atttgggaaa aggtgggtta aaccaagccc ggctccctca ctgtaggatt actcagtgcg 35400 tttagtatgc aaatgtgcct ctgaatctaa gacaggacca cagaaacctc ttcagtgttc 35460 ctctggaggg agggaccgcg ggggatccac cgcaggggcc tgggtctgca ctggcctggt 35520 gaagtgcccc cttagtgctt acaccatgcg cggtgagagg ttggccctcg cctcccccac 35580 cctctgctgg ccttacctca ccacctctgc actcgcctcc cagccggctc atgactaact 35640 cctgcctctt cagagccaat cggtgctgcc aggttttcca tttcaagtga tcccccgcct 35700 gggccaaaat gtttggattt tcaggcacgg aggggagatg gacctcaggc caaaccatgc 35760 tgggtaaaac tgagggtcaa ggctgtgctc agcaagtgct ccagccctgg ccgtcaaacc 35820 catagtgtgc acagcgtgca ggaggtggct gggtgaatga actcagtcat agcccggccc 35880 ctcactcggg gctgttccca agttcccacc gccagccagg ctgggtcaga gcctcgtggg 35940 gccttcctgg gcttccctgc cccacagcag gagttcgtat ggagagtctc gagtgaggtt 36000 aatgggtttt cttcctcttc tttttttttt tttttaattt gagacagggt ctcactcttt 36060 ttacccagcc agggtgcagt agtgcaatta tagctcacag cagcctcgaa ctcctggctt 36120 caagcaatcc ttccgccgca gcctcccaaa gtgctgagat tacaggcacg tgccaccttg 36180 cccagctggg gtttctgctt tttacttttt ctcttgtttc taaactcaat acaaagaaag 36240 atattacatt tataatcaga aaaaccaaca aggaatatta tttcaaaatt ggaaaaggga 36300 ttaaagaaac aaaccaagaa acctctgcga ttcctgccca tcggagtcag tggttgttag 36360 tggttggctt aacacaatgt tttaggaaga aatagaataa cagaaagcaa ctccagtgag 36420 ctgagccctg gctccgtctg tggcgctgca tcagtttcct gcagctgctg taacgagtgg 36480 ccacaagctg gctgggtcac aacaacgccc agccatcctc tcacagctct gcaggccaca 36540 catccgagat cagggtcacc aggctgaaat cagggtgtcc actgggcata gccctctgga 36600 ggctctaggg caggggttcc cagccccgtg tgtcctatta ggaactggcc tgcacagcag 36660 gaggtgagtg actggcaagc gagcgaagct tcatctgtat ttacagtcac tccccattgc 36720 tcgcattact gcccaagctc tgcctcctgt ctgatcagcc atggcattgg attcttatag 36780 gagagtgaac cgtattgtga acggcacatg tgagggatct aggttgcgtg cttcttatga 36840 gaatctgatg cctgatgatc tgtcaccgtc tcccatcacc accagatggg accgtctggt 36900 tgcaggaaaa taagctcagg gctccaactg attctacatt atggtgagtt gtataattat 36960 ctcattatat attataataa taatagaaat aaagtgcaca atcaatacaa cgtgcttgtg 37020 gccgggtgca gtggctcaca cctgtaatcc cagagtgaaa ctctgtctca aaaaataaaa 37080 aataaaggcc aggcacagtg gcttatgcct gtaatcccag cactttggga ggccaaggct 37140 ggcggatcac gaggtcagga gttcaagatc agcctggcca atatggtgaa accccgtttc 37200 tactaaaaat acaaaaatta gccggacacg gtggcaggcg tctgtagtcc cagcttcttg 37260 ggaggctgag gcagaagaat tgcttgaacc caggtggcgg aggttgcagt gaactgagat 37320 agtgccactg tactccagcc tgggtggcag agcgagactc tgtctcaata aaataaaata 37380 aaataaaata ataaatataa tacacttgaa tcatctcaaa accatctccc cactccctgg 37440 tctgtggaaa aattgtcttc cctgaaaccg atcccaggtg ccaaaaaggt tgggggccac 37500 tgccttcatc gcctgcccct ttgagcctct ggtggctgtg ggtgtccctt ggcttgtggc 37560 tgcatggccc ttaccttcaa caccagcatc tacagatctc tccgggcccc atctccactt 37620 ggccatccct gtctgtgtca aatctccctc tgcccccgtc ttgtatgagc accgagactg 37680 cctttaggga ccacctagac catccagggt gctctcgcca cagcaagatc tgcaactgaa 37740 tcacagatgc aaaaactctt gttccaaaca aggtcccatt tgcaggtcta gggattagga 37800 catgctatcc ctggggccat tattcagcct tctctcgtga ctatgatccc tcccttcctc 37860 cccagcctcc cacctcggct gagatgctgt ccccacctcc ctcactgtct ggctgcctgt 37920 ggggctgtcc tccaggctct ttgggaggag gtggttgctt gatgtctccc agaaggctgg 37980 gaatggtcct ccccaccccc caggaagatg tcctttctgc caaggagatt gcatttgggg 38040 tcctatccca ggcagagagc ggacgggact gtggcctgaa gtggcacttc agggcctttg 38100 gctctgtcat ctagccgagg gctgtgcatg ggcctcacct ggtcacaggt aactcacctg 38160 gctctgtggg gcagggattg taaactcaga ggcctgcggg gtgtgtcgag gtagaggggt 38220 gcaaatattg taaatttgtt gggggccttg gggagcagca cagactgaaa agtgttttgt 38280 ctgaagagca gaactgtctt ataccagccc tgtgcggcca ggcaggaagg cttccgtggt 38340 gcggccacgc gtcctccctt tctcaacaga agctgacagt ctggagtttt cagagagatt 38400 gcctgagttc tcagccttgg cacaaacaca cattctcttt aaacaggctt gggccaacag 38460 aaccagcctc cgtgtctcgg gtttgaatga acccttgagg tgaagcttaa agacagagag 38520 gatgcccctg attcccaccc cagggaccca cattgtaaac ccccacctgc tctgctgagc 38580 ccttggcctc agcatggacc ctgaccatgt gctggtgggg accccccagg taagtaagca 38640 gcctctgagg accccggatg aacagtgggg aacagcactg atcccccagt ggggccccga 38700 gttcccggag aggaagactc gctccctccc aggggacggc tagagactca ctgactcatg 38760 cgtgtgtggt aggaatcttc caggaagtcc ccgtcccgtt cgccctctct gcctgggcgg 38820 ggacggcaac tgcctctgtc actgcagact aatgggacgg aggggggtga cttctcaggg 38880 ttcctcctgg gcaggtgctc cggaaccttt tctcagcacg ctggcctggg gcacggccgt 38940 tcctcctgcc cagccacgtt ggggtacagg gtgaagaagg gctggggcca gcccaggaca 39000 gaggaaggcg aggcaggcac gcaggaactg ggctttttaa acccttaagc ccaaggaaat 39060 cgtagcatcg cgggacaggg aaaatgaaag actttggaag tcgtcaggaa tttgactctg 39120 tgagttggtt tccaagagtc taagttaagc atctccaagt ggatattaaa aaggagcagc 39180 aagcctcggg gcggcggggg ctggaggagg tggagagagg aggctgccgg aagccgcact 39240 cgggacctct gcagccaccg accagaccgg gcggccggga ctctgggact ctcgcaggca 39300 gacccggtgg tctgccggac tcctcggggc ccacttcggg ccctctctcc tgcctcctat 39360 ttttggattt ctctcctttg ctcccttttt cctcccgttt tgaagagaca atgctacttc 39420 agtttggagc acaaacatat gatcagcaca tggaaatgtg gtaattcgga tgcattcgtg 39480 attgcaacag attgaagaaa ttagaccaga caaagagtgt ttttagagga ggaggaggag 39540 gaggaggagg ctgagagagg gagggcgacg ggggtgagaa aggggaggcc gcctctgagc 39600 gggacgccgg gactcccgcc gctgctaaat atatccgtag gaatggagag ggaccggatc 39660 tcaggtacgc agacagcccc ctccccatcg gccgcccccc actgccctgg actcggggct 39720 ttatttatgc ctgggggaat aagcatgcaa agggcgcttt tgctcatttt tcacagaaat 39780 atttcttttc tttttgacgg ttccaagctc gtgggatgaa ctccgtctca gaagctaagc 39840 tctcctgagt ctggctttta tttaaactcg gctctcctct ctcctggcta cttccctttc 39900 attttccagt gtgccattct tgcatgtcat ggccactgtc aatgctgagg ctgttggcgc 39960 cgaaaccttg ggagggtgtg ggggacctgc ccccctggct cgggtctggg gcggcggcgc 40020 ttggacctgg ctggtggttg gtttgtccac tgtgtggttt gttttttgct tccagccaaa 40080 gtctgtcttc aaggctgcct cggtctccta cctaaaatag catttctgtg ccttcctggc 40140 agttgattat agagggggaa gctcccggcg ctcagaggag cctggcgtgt gtgtgcacgt 40200 gtgtgtgcat gtgtgtgcgt gtgtccattc acgctggcag cccccttgcc gcaggcacag 40260 acccatcagg gcgtgaacag gcaaatgaag agaaaggggg ctcccctgcc tttagttcac 40320 cccagctttc caggccctcc ctcccaggcc cagcctcctt ggtcccttca ctcacatgcg 40380 gtgccgtggc tgccatctca cgtggccagc gccgtcatcg gtaattagca gtgatgacag 40440 tttctgccgc tcatgccgcc ctctgagccc agcgctggga gacatggggt ggctgagcca 40500 agctccaggc tttgggtatt ctgaagtgac ctacgggcca tggagcggga ggtcgctaag 40560 agtgtcaacc cctacgtgcc ttgggccctg gtctgttggt tgccactatg tgtgtgttgg 40620 ggggtccctg agaggcctga gagagggagg cccatctcgg tggctcctct ctaggacgtg 40680 tggtcccctc caccactgct cccagggcca catctttttt tttttttttc tttgagacgg 40740 agtctggctc tgttgcccag gctggagtgc agtggcgcga tctcagctca ctgcaagctc 40800 cgcctcccta gttcatgcca ttctcctgcc tcagcctccc aagcagctgg gactataggc 40860 gcccgccata tttttttgta tttttagtag agatggggtt tcaccgtgtc aaccaggatg 40920 gtctcgatct cctgatctcg tgatccgccc gcctcagcct cccaaagtgc tgggattaca 40980 ggcgtgagcc acggcgcccg gcctcagggc cacatcttga ttgtcacgtt gggactggtg 41040 gagcgggtgt gtgttgtgcc gctgagcaca cccagtcggg cacagcaggc ggacctcagg 41100 agggggccag gggagacggc agaaggcttg ggtggcagtg aaactgcatc ttatctgttt 41160 gagctcgggg gctcaggccc gctgggacgg gtgggtgtgg agcccagcgt cctgctctcc 41220 gcccagcagg agccgcaggg cagggagcgc tgagagggac cttcgtcagg cttgcacagt 41280 ggagccgtcc tcggagtgac caccccacca ggcagcctgg gcagaccaca gtgggtcccc 41340 tgcctcctgg gccaccagcc ccaggaggac gtcactccac ccgcctggct ggcaggggcc 41400 tcggggagcc tcgggttcgg ccttcacttt atagatgatc tagccgaggc ccagatgggt 41460 gaccagcagg ggatctgaga gctgagcaga gaggcgtggg tttgggggtg gtgctccctg 41520 gggagctgga agtgatggca ccctcccagg ctcacaaaac acgggctttt catgaactga 41580 acaaaacact ctttgaaagc agccagtgct gtgccccaga gaccactctg atccctgctg 41640 cccttggctg aggacagcac agccagggat gaagcgggga cctcccctcg ggctgtgcct 41700 tgatgaaaga tgctttctac aaaatcccat tcggatgtgt tttcatgtaa gaaaacgtac 41760 atttttagaa actcagttgt aaactggctg ccttccgaat gaacacgaca gtcccggagc 41820 tgtttccctt aatgaggttc tcgtcctggg caaactttag cgctggtctt taattgtcac 41880 tgaactcccg cacagtccct ggggaagtga cttccttcct gtccctgctg ggtggccttg 41940 agcaagccac ttggcagctc tgggccgcag ttccgtcatc tgcaaggtga ggggtgggag 42000 cggcacggcc cctaggcagc gcccccacct cctgcgggtt tctgcgcgtg tcctgagttt 42060 tgtgggcgcc tcttccctca ctgaggggct cttcttctct gcagggcatg gctcacgccg 42120 cgttgtcagg ctgcaagcca ctgcgagagc tgctctgatc cccaagcatg ctctggcctg 42180 aggaggagcc atggggagga cgctgtgcct gtgtgacaga ggcctgcccg gcagatgccg 42240 gcccgctgac ttccagacgt ggctgtgggt gcctcatgcc ccactgggct ggcgtgtgag 42300 gcgtgtccag ctcaggctgc cctacagctg cccaggaagg gtttgtggga gggggtggtc 42360 ctaccctggt gagtccacgg tggtctgcca gccccaggga aggcttagga gccccaagac 42420 ctgccctctt gtccctccct cggcagtgtc tggctccggt ctggtttgtg aacgggggcc 42480 tgggtactct cccgccctcc ctgggggctg tggccttccc ctgggaaggt gctggagggt 42540 ttgtcagcag ggccggcatg agtcatggag tggtgactgg ccgctgaggc atggaaggcc 42600 actccttcca gccaagggtc ggagcttttt ttttgttctg gaacggcttt gtggctttta 42660 caaattaagc agttttatct tgttccaaga gcttgtattt cagcagggag agagtctcca 42720 agaagggaac tttccactgg ggagctctgt tgggctggga ggctaggaac aggccacgag 42780 ggagggctgc aggcagggga agtggccgtc tgtgcatggt catgaatgca ggcccggggt 42840 cctggagggg gcttggccac gctgtcgctg gacgtctgtc cccaccaggg tccatctgat 42900 gcagtacggc acagggtaaa gcccagctcc tcttacgggg ttcctgggtc atcagtgggc 42960 ggggaaccga ggcctcctgg agggcggtgc ctcagccctc acccctccct cctgtccctc 43020 gctgtgctgt ccccgatggc ctctgccatc ccctgggagt tcttacccct ggacgctcgg 43080 tgcctgtccg gtctcaacct ctccagctct gcttttccat ctccgaggtg agaggcctgg 43140 cctgacgcgc tctgcacccg cttcctgccc agccccgtgg gaactctggt ccctgtagtg 43200 gtttcctggg gctgccatca ccaagtgcca caaactgggt ggctcaaaac accagacatt 43260 tcttctctcg ccgttctgga ggccagaagt ccgaaatcac ggcatcagca ggcctggttc 43320 tttccggagg ctccgagggg gagcctgctt ctcgcctctg gcagcttctg gcggctcccg 43380 aaacccttgg cgttccttgg ctcgtggcca caccactcga cctctgcctc cgttgtcacg 43440 gggcctcctt ctgtgcccta aatctccccc tgtctgtctc tcatacggac agtctttctc 43500 ggatttaggg cccactgggt aacccaaaat ggtcccatct caagatcctt aacttcataa 43560 cgtctgcaaa gacccttttt ccaaataggc catgttcata ggctctgggg tggatgtaaa 43620 ttttaggggc cacctttcat ccccctgttg tccccgtgtg tctggatgca cagcatggtt 43680 ccatgtccca gactccttgc tggacccctc tggccctttg gggtggcctt tggccttttc 43740 cactcgtttc tgtgctcctg gtgaggtgtc ggggtcgggc ttagcccctg caggaattct 43800 ggggacagca tggagccggc aactccccac caggcgtctt cctacctgcc cagagctcat 43860 ggttgtgagg ggtctctcct tgtggttttg atttgcaatt ccccagtggt tagtgatgtt 43920 gagcatcttt tcgtgtttat tgctcatttg cacatattct tgcagaaatg tctgtccaag 43980 tcctttacct gtgtttgatt tggatgattg ttgttgctga gtgttaggag atctgtagat 44040 taatatccag atactaatcc catatctgac ctatgatttg ctgccattcc atggattgcc 44100 ttctccccac gttgttagtg ccctttgata tgcaattttt tttttttttt ttgagatgga 44160 gtctgactct gttgcccagg ctggagtgca gtggcatgat cttggctcac tgcaacctcc 44220 gcctccctgg ttccagcgat tttcctgcct cagcctcctg agtagttggg attacaggca 44280 cccgccacca cacccagcta atttttgtat ttttagtaga gacggggttt cactgtgttg 44340 actaagttgg tctcgaactc ctgacctcaa gtaatccacc cgtctcggcc tcccaaagtg 44400 ccggagttac aggcgtgagt caccgcaccc aggctgatat gcaaatattt taaacttcta 44460 tgacgttcca ctttatctat ttgttcttct gttgcctgtg cttttggcgc catatccaag 44520 aaatcattgc caaatgcaac gtcaggaagc ttttcccctg tgttttcttc taagagtttt 44580 gtggttttag ctcttgagtt taggtctttg atgcaagttg agttgatttt tgcatgtggt 44640 gtaagggctg gtccagcctc atgctctggg ctcttgattc acttctcttc ttttctcacg 44700 cccagctggt tccgctgggt ggcggggagg agtggggaag tcccgggctg ggcctgcact 44760 cgatcatccc ctctcaggcc agccagggag tctcagctcc tgcccaggac ctggctggac 44820 gtgctcccta ccgggaaagc ctgggccgtc tttctaggct gatggcaggg ccagcccggg 44880 gcgtcctgag gcctgccctg cggacatgcc ccttgttcta ggtggtgtgg ctgcccggcc 44940 tgcgtgtgag accagctgtc tgtgcttcag gccatggagg ctgagtgttt ccagcctgtc 45000 cccttgctcg gctctccctc tggggaagcc cctgcagccc attctctgcc tccgcttctg 45060 ccatctgtgc ctttgtctgc ttcctgtttg gaggtggtca tccctggggc cacccctcat 45120 gatctggaca caagtctcca tcctgaagcc accacccaaa cccctgtgcc tcaaacccct 45180 cccacccacc acatgggttt ccactgtgac caactcagca gctgatgaag cttcccttgg 45240 ggctctccta gcaacgggga gctggctttc ccggaggcct ggcctctccc taagtggaag 45300 tggggcgtga gggtgtcagc ctttttctgc tgcctggtgc tctaggttgg cttgtcaccc 45360 ctggaagcac ttgccatcct tatacagcac cccacaccca cctccccgcc tcctacccct 45420 tcttccaagg ggtcatctct gcttccctcc ccacccaacc tcacccatgt ggtccgccca 45480 gcaacctttg acccccaaca tgacaaaata aacctccctt gccggtcact cattcattca 45540 ttcagcattg ggtgctccct gtggacttgg cgctggggtc ccgtggagga caaagccaga 45600 cacagtcctt gccctcatgg gactgcacaa gtgcaagacc acatcagtaa acgtgaaaca 45660 caggaagtga caggtgtgac aaaggggacc agtggcagga cagaacctgc ggttcgtagg 45720 accaggtcag gagggctgcc tcggggggac accttcgggc tgagcgcaga aggatgaggg 45780 gagtaaacca ggctcaaacc cagcaggcag aggcgatcgc tgcaggcaac cggcaatgtg 45840 ttcaaaggcc ctggggcgcg gggggctgag gccggcagca cggcaggaag taagactggg 45900 gttgaaagag actgactgtc atgttgtgaa atatacactt ggttttcatc tccatttcct 45960 ggcacacaac tcctaaaatc cttggaatct ccaaagtgat gtctttttgg atgctcatga 46020 ttgacagacc agctggcagc ttcaggatgg ttcccaggga agaccaggta gaatcacaag 46080 gttcagcacc accccgcaac ctccaggtag gggagagggg ctgaaggtta agcagatcat 46140 cagcggccaa tgattgaatc aatcatgcct tcgtaatgag gcctccgtga acactcagaa 46200 ggatggggtt ccgggagctt ctggatggat gagcatgtgg aggctcctgg agggtggagc 46260 gcctggggag cacatggaag ctctgcgtcc ctcccccata ccttgcccta cacatctctt 46320 cccctgtatc ctttgtaata tcctttataa taaactagta aattccatga gccccaggaa 46380 catgtgtaaa agaaaaaaaa aagaataaac catagctgct gtagcaagtt aatcctacca 46440 gcactggctc tcatctgccg accttacctc tggcaatgcc tccctctcct gggctcctgg 46500 gacccctccg gccccaccac ccctcctgta gtggtctcgc tggctgctgc cctcaggtta 46560 gtttattttt acccggcctg ctcccaccag gggctgaggc ctccttgctc actccagctt 46620 cctggcccgt ctcttgctct gggcaccccc ccactccgaa cggccagagc ttctgaagcc 46680 gctcgctgtg tgcccccgcc tggccccatg catcccgcac ggtgctcccc agggtctccc 46740 actggcaagg gcattggcat agattctggg gctgccttgg ttcaagccca ccctgacttg 46800 gagcctgagg gtccctgagg gggtcctgaa ggccagggca ggcaaggctg gcatgctctg 46860 ggcagtgggg gctgggtatg ggaggggatc gtgggtgggg agattcctct taaccagcgg 46920 cccacgtttg gagactgatt tgggctccag gctacgcctt gaaattggga cagagagtgg 46980 cgcagatctc agcccggaga ctccctctgc ctgtggacgc cctcatacct ccatccgtgg 47040 agccaccctc ctcttttttt ttctaaatgg ggaaactctg acttgaacac tgaataaaca 47100 acacaccctc gaaatcagcg aagaggcact ggctctgaaa ctttgccatg aaagcttgaa 47160 aatgctcttt ggaccgattt gctggaacag acgggtgtga tggggctgcg gggtttcagg 47220 tggcaggagg cgtccccgtg cctagggcat cccgatgctc agagtttccc cgtgcccagt 47280 gtgtccctgt atccagggca tccccatgcc cagggtgtcc ccgtgcctag tgtgtccctg 47340 tatccagggc atccccatgc ccagggtttc cccgtgccca gggtgtccct gtatccagag 47400 catccccatg cccagggtgt ccccgtaccc agggtgtccc cgttcccagg gcgtcctgtg 47460 cccagggtgt ccccgtgccc agtgtgtccc tgtatccagg gcgtccccat gcccagggtg 47520 tccccatgcc caggcactgc ctctccccac tttcctaatc tccctccacc aacaggtgtc 47580 agctgtgaaa tgcctgctgt gtgtgtcctt tggttgagtt catcttgtgc tcttaagttc 47640 ctgttagaca caggcaggct gctttagttc ttctggcaaa tgttttgttg ttgttgtttg 47700 atacggggtc tcactccgtc acccaggctg gagtgcagtg gcgccatctc gcctcactgc 47760 aacctccgcc tcccaggttc aagcgattct cctgcctcag cctcccaaat agctgggatg 47820 acaggcgtcc gccaccatgc ctggttaatt tttgtatttt tagtagagat ggggtttcac 47880 catgttggtc aggctggtcc cgatctcctg acctcaagtg atccacccag cttggcctcc 47940 caaagtgctg ggattacagg catgagccac cgtgcctggc ccgtctggtg aatgtttatt 48000 gaggcctact atgtgcagcc cctctcttag gtgcttggcc tgtaatgagg agcaacaaag 48060 acacagtcgc tggtcgcttg ttacttaaca gttggaactg agaggcagtc cacaaatgag 48120 caaatccata ggtggtttta gatgaggact gtgaagaagc taagaacagg ttgctggggg 48180 tgcatatctg tgtgtgtggc gaggggatta atggaagccc tttctgagtg gtgacactga 48240 gctgaagctg taatgaccag aaggacccag ccaggccaaa atccaaggga agagcaacct 48300 ggcaaaggaa acagcaggtg tgaaggcccg aggctggagc ctggggaagg tgggagtggc 48360 tggagtgtgt tttcagagac gggccatggt gacaccaatg cgacaggcag ggccaggtcg 48420 tgccgggcct tggaggccct ggtgagggct tgattttatt ctcactatgg tgggacctca 48480 gtgccctgtg gctgctgaga atggccaggg gcaggcaggg aggcctgcta gggaggaggc 48540 tgctgcaggc cctgcagctg gagagggagg atcaggatct ctttagagag gaagttggag 48600 agggaggatc tctttgattg ctggatggac ccacctgcct ggctgccccc gtcagcatcc 48660 agcagaggcc actggatgct gacaggtggc cggccctgcc cagccttgca ctgccctgtg 48720 ctgccctggt ggctgccggc tttaggagga gcgcttttgg tgtctgagcc cagtggtcct 48780 ggctgtggtt tggtacactt ggccgtgggt gaggccaagg tggtttggat cctgggaagg 48840 ttgggtacct ggcagcctca aggcaggagc tggggtgttg gaggaggaag cacgctcatc 48900 cctcgttcct tcctgtttcg tgggatgctg agtctctggg cagggacatg gtgagccctg 48960 gtgtgatgca cttaacacct gctggtgccc ccatccccaa gcaggaaccc tggtgcctgg 49020 tgcctgagga ctgctgtcca ccgtcccacc atccttcagg tttcttccca gcctctgact 49080 cggggcaagg ttcagatatc cagaacattc ttggctggct cttggagctg gggtgaggca 49140 gaacctccct cccatattta cagcaccagc caaggcttcg gggtttggac accatccctg 49200 ggaggggtga gcaggacaag tgaggtctcc agacttgggg tggcttcgga ctggccaggc 49260 aggtgggtgg gggctgcagt ccatgccccc gctccaggca acacagtcga gctgcagccc 49320 ccgctccatc cccagctggg gctccctgtg ctcaccttct gcttccttcc tctccctcgg 49380 aatggggggt ggacactcca agactagcct cccagccact ctccctgcct cctgcctcct 49440 ctccttcggg acagacccct gtgatcgctg ggtgttcctg atgctctgtc ccctctgcgt 49500 cctgtgccgt gggtgagaga gggcttcggg gggacttccc cctcttggag cacctgctgc 49560 tccgggtgcc tctgggggcg ggcccccacc tcacattgtg gagctggtgt aggaaggaag 49620 gtgccgggag ccagctccaa ttcacgtgct ggctgtggcc ctcaaggtgt ggatggcagg 49680 aggtggtgag acagggactc attgatcatg ggactgacac cccctcatgt tgatgtgggc 49740 cctgagccat aatctcacca gctcctgagt tttggcgctg ctcttggcga tggcgtggac 49800 tcagccaggc tctcgggcag cctttcctgg attcttcctc cgttctcccc tgggcagtgt 49860 ttctgttcac ctggaaagga tgggtaggac ttggagacaa cagggattca aagaagtcgg 49920 gagtgggggc acctgtgcag ctcaccctgc agaacagaca atttggttaa agcctaaagc 49980 ctgctgtcag gagcctcgct tgcctctcag agagcacatg gcttgaccat cacggggact 50040 gggggagagg cacaggcatg cctgtccggc agcagaaggg aaccccgggc ctgggcctct 50100 ccattctgtg gcgttgtctt tcctcagagt tgcactgtct ccttcactgt ccctgcctgg 50160 ccccagtgct catgtggctt gtggccctca gtctgggctt ggtctcccgc aattcaccct 50220 gcccagcccc acacagcttg tccctccagc tgggaatcgg agctcacctg gagtcccagg 50280 cagcagattc gatgcagtga tgcagggctg tcagccatgc cagcaggccc tgctgctcac 50340 agagggatgg gtattgctgt tgacaataat taaagaacta cggcttcagg ctgggtacag 50400 tggctcacac ctgcaatccc agaactttgg gaggccgagg caggagaatc aattgaatcc 50460 aggagttcca gaccaggctg ggcaacatag caaggctttg tctttacaaa aaataaaaaa 50520 taataataat aataaaaact acagcttcag aatgattgac ttcagcatgt ttataaagtc 50580 aagggtcttc agtgtcctgg gcctatgtca ctgcgtcaga gggagagagg aagaggctgg 50640 ggtgatgggc actggggctt atgctcctcc tggaatgggt ggtcttggac tgtgcctgtg 50700 tgatatgttt gtcgagcggg ggcggtgtcc actgaggact ggatgttgag gtgtgggtgg 50760 ggggaggtta tgaagcactg ggcatttccc gtgcaccagt gccccgagat tgcagagagg 50820 ggacccgccc agcctgggca gggaggcggg tggcagcgag gaaggggaga ggaactcggg 50880 tgcagaaagc ctttcctcca gcaggtggcg ccgcaagctc tcgagagtcc agctcctgcg 50940 gggtttgcat tttcactgaa tttgtgggca gaggctgcct gggtgtagtt tccgccaact 51000 gtgactgctc actgcgggcg aggggaagtg gagtgcagag aatgcaccgg agggcagatg 51060 accagccccc gcacaggcac gggggtgcct ccttccccgc acaggcacgg ggggcccgag 51120 cccttggggt tcctgtccta actgggcggg gaaagggagg gttggaagct gagttagggg 51180 gaaagggggt ggtctcctgc catctctttt attttatttt tcctattttt ggttgatagg 51240 tttcaatctt ttttacattt ttccaacttt ttgccgtaaa acttttcaaa catagaaaag 51300 atgaaagagg gctgagtgtg gtggctcatg actgtaatcc cagcactttg ggaggttgag 51360 gtaggaggat cacttgagcc caggagttca agaccagccc gggcaatata gtgagatccc 51420 atctctataa aggatacaaa aaattagtca ggcatggtgg tgcaggcttg gagtcccagc 51480 tactcggaag gttgaggtga gaggattgct tgaacctggg aggttgaggc tgcagtgagc 51540 tgggattgtg ccaatgcact ccagcctggg cgacagaaca aaaccctgtc tcaaaaacaa 51600 aacaaaacaa aaccacaaaa aagaaaccat gaaagattct aaagtaaaca cccatgcacc 51660 taccacctag attccacagc aaccattttg ctgtttgctt caccacaaat ccctctggcc 51720 accagcatcc acgctggttt tgatgcactt aaaataagct gcagaaatca gcacacaaca 51780 tcctgtcaac acctcagttt gcatttcatt aactagagtc cggcatttgt ctgtgattat 51840 ttttgttttt ctttgaagta aaatgtatat accctgagat gcacaggtgt gaaacgttcc 51900 gttctttgaa ttttaacaaa ggtatccacg tgtatcccag cctgaccaga acatagaaca 51960 tcactatcac cccagtaagt tcctcatgcc cctccaggtg catcacagtc cccaccttcc 52020 ccagggcaac cacaattgtg ctttttttcc accacgaaat aattttgcca gtttgagtgt 52080 ttcttagagc tacccatgtt gctgcaggtg ccagcgattt gttctgtttt attgctgagt 52140 aacgtccact gtgtgaacat tctgtgggtt tttagtcatt ctcttgttga aagacccctg 52200 gctgtttcca tctggaggct cttatgagta aacctgttac gctggttctt cttgtacaag 52260 tttttctgtg catatgggcg ttcatttatt ctgtagaaac acctagagta ggtatagggt 52320 aggtatacat ttagttttat aagaaactgc cagatctttt cccaaagtgg cccttccatt 52380 tcacactccc accagcaatg gatacgagtt ctagttgctc cacatcctgg ccaacatttg 52440 gtgctgtcac tctgtgaaat cttagtcatt ctggtgggcg tgtagtggta tcatctcatt 52500 atggctttaa tttgctttgg cctgatgact aatgcggttg agcacatttt catgattggc 52560 tcttcatata tttttccttt gtgaaatgtc ttttcaaatc tgttgctcat tttaaaattg 52620 ggttgcttga ctttttcttc tggatactga tcttttgtca gatacgtgtt ttacaaatat 52680 tttattccag tctgtggctt gcctgttcat tttctttcct ttttcaagaa caaggtctcg 52740 ctgtattgcc caagcaggtc tgaaactcct gggctcaagc tgtcctcctg cctctgcctc 52800 cccaagagcc ggttttacag gcatgagcca ccatgcccgg cctgttcatt ttcttagtgg 52860 tattttccaa taagcaaaag tgtgtcactt taatttttat gaagtctaat ttaacaaact 52920 cctttctttg tggttctctc tctgtgttct ttgtaagaaa cctttgccta ccctgccaaa 52980 ttgcaaagat atttatgttt tcctttagaa ggcttagagt tatatagctt ttatgaatta 53040 acttttgcat atggtgtgag gtagagggtc agggttcatt ttgttgtcgt tttatgtgtt 53100 tattcagttg ttccaaactt catttttttt taaagctttt attttgtatt ttcttggtga 53160 cttatgaggt cgcacaattt tccaagatcc ttgttggtca tttacgtatt ttcctttgta 53220 aaattatctg tccacgtctt acttcttttt aaaattatgt tgtttcaaga tcgagtgatt 53280 tctgaagcct tcattttata atgcttgaaa gaatgaacac cttgttcccc agctacaggc 53340 ttctgctctt tgtcctgcag ctgcacagtg gggtaagact tgggttttgt tttgttgctg 53400 ctttgttgtt tcttcatttg actgtttccc catgggtctc atttaaaaaa aaaattggcc 53460 gggcacagtg gctcacgcct gtaatcccag cactttggga ggccgaggcg ggcagatcac 53520 gaggtcagga gatcaagacc atcctggcta acacggtgaa accccatctc tactaaaaat 53580 acaaaaaatt agccgggcgt ggtggcgggc gcctgtagtc ccagataatc gggaggccga 53640 ggcaggaaaa tggtgtgaac ctgggaggcg gagcttgcag tgagccgaga ttgcaccact 53700 gcactccagc ctaggtgaca gagcaagact ctgtctcaaa aaaaaaaaaa aaaaaaaatg 53760 ttgtttcata tgttttttat atattctgga tataagtcct ttatcagata tatgtatcat 53820 aagttttttt ttccacattg ctcctttcct tttggttttc ttaatgatgt tatttaatga 53880 gcaagagtat tttgttttca taaagtccaa tttatcaact ttttccagtt tcgatttatg 53940 atttttgtga cctatggagg aaatctttgc ctacactaag gtcaaaagaa gttctcttat 54000 tttctagaaa ttttatagtt gtatattcta tgattccttt tattttttaa ttttttaaat 54060 ttttacattt tttaacctat tatagccgtc aggatgttgt atgatccatt ttaaatcagt 54120 ttttgtattt ggtttgaggt cagggttaat tcttgttttt ctatactcat atccagttct 54180 agcaccgttt gttgaaaaga cataccttac tctattgaat tacctgacac ctttgctaaa 54240 aatcattgac tgtatatgtg gccctatatt agtatatgta cgtatataca tgtaggccct 54300 gtgttgactg tatgtgtggt cctatattag tatatgtacg tatatacata ttggccctat 54360 gttgactgta tatgtggtcc tgtattagta tatacatatc agccctatat tgactgtata 54420 tgtggtcctg tattagtata tgtacatata tacatgtagg ccctatgttg actgtatatg 54480 tggtcctata ttagtatatg tacatttata catgtaggcc ctgtgttgac tgtatatgtg 54540 gtcctgtatt agtatatgta catatataca tataggcccc gtgttgactg tatatgtggt 54600 cctgtattag tatatgtaca tatatacatg taggccccat gttgactgta tatgtggtcc 54660 tgtattagta tatgtacata tatacatata ggccccgtgt tgactgtata tgtggtcctg 54720 tattagtata tgtacatata tacatgtagg ccccatgttg actgtatatg tggtcttgta 54780 ttagtatatg tacatatata catgtaggcc ctatgttgac tgtatatgta gtcctatatt 54840 agtatatgta catatataca tgtaggccct atgttgactg tatatgtagt cctatattag 54900 tatatgtaca tatatacatg taggccccat gttgactgta tatgtggtcc tgtattagta 54960 tatgtacata tatacatgta ggccctatgt tgactgtata tgtggtcctg tattagtata 55020 tgtacatata tacatgtagg ccctatgttg actgtatatg tggtcctgta ttagtatatg 55080 tacatatata catgtaggcc ctatgttgac tgtatatgtg gtcctgtatt agtatatgta 55140 catatataca tgtaggccct atgttgactg tatatatata tgtggtcctg tattagtata 55200 tgtacatata tacatgtagg ccccgtgttg actgtatatg tggtcctgta ttagtatatg 55260 tacatatata catgtaggtc ctatgttgac tgtatatgtg gtcctatatt agtatatgta 55320 ctgtatacat gtaggtccta tgttgactgt atatgtggtc ctatattagt atatgtactg 55380 tatacatgta ggccctgtgt tgagacacta ttgtgttttc ttgatatttt gtccattcct 55440 ttgctgatgc cacatcttga ttaatgtggc tttacagtaa gtcttaatat aaagtctctc 55500 aaatatctaa aatattactt tgaatattct aggtcctttg agtttcctta taaatttaag 55560 aagtagcttg ttgatgtcta caaaaatgca gtgtgaattt tggttgagat tgtgttgaat 55620 ctgtagatca attaaggaag aattggcatt ttaacaatat tgagtctttt gtatagatgg 55680 tatatctccg ttttaaaggt ccttttgtat ttcttttatt tctctactga aaaaaaatct 55740 ctacagaatt acattgtttt gtagttttca agaaaaagat cttgcatgcc atttgttaaa 55800 tttattccta agaattttac ttttggcact attttaagct gaaatagatt ttaaatttca 55860 tttttaatta tttgctgcta gtatgtaaaa atacaataga tttttgtatg taaatcttat 55920 atcctatgat cttttccaaa gtcatttatt actctggtaa tggttttgta ggtcttttag 55980 gatttaaata catagtttta cttctttctg atcttgatgc cttgtttttt tttcttgctt 56040 tattgcactg gttagagctg ccagttcagt attgaatagt agtgattagt ggacatcctt 56100 gcctgtgcca aacttataat gttaacttta gatttgtcat atatgacctt tgtcagattg 56160 aggaaattcc cttctattct taatttgctg aaatttttta acatgaatgg gtatgatttt 56220 agtaaatgct ttttctgcat ctatggaaat gatcattgtt ttgtctttta ttcgtttaat 56280 aggataaatt acaatgattg atttttgccc cccgtttttt tttttttttt ttttaaagaa 56340 acagagtctc actcttgccc aggctgtagc acagtggtgc catcgtagct cactgcagcc 56400 tgaactcctg gacttaagca atcctcccac ctcagcctcc taagtagcag ggactatagg 56460 cacatgccac catgccaagc taatttttaa tttttaaaat tttttgtaca gatggggtct 56520 cattgtgttg ctcaggctgg tctgcaattc ttgagcttaa gcaatactcc cacctctgcc 56580 tcccaaagtg ctgagattac aggtgtgagc cactgtgcag gcctgatttt ttaatattga 56640 accaaccttg catttctgga agaagtccaa cttgcttatg agatatcatc ctttttatat 56700 attgctaaat ttgatttgcc cagtttttaa ggatttttgc gtgttgattc atgagggata 56760 ttggtgtggt attttctttg tttgttagtt tgtttcggta atgtctttgt cagcctcatt 56820 ttggcttcat aaaattagtt tggaagtgtt cccttctctt tgttttctgt gttttcataa 56880 ggttgatgtt gtttcttcct taaatgtttg atagaatcca ccaagaaaac cgtctggacc 56940 tagaattttc tactaggaaa ggtgattgtt tgtttttaat cacaaattca atttaatgta 57000 tagaaagagt tattcaggtt tttttacttc cccttgtctt acttttggta agttgtactt 57060 tgaaggaatt tgtccctttc aggtaagttg ttgaatttac tcatttaaag ttgttcgtaa 57120 tacaagcata cctagggttt gcttccagac ctcggcaata aagcaaatat tgcaataaag 57180 cacgtcacac aaactttttg gtttcccagt acatataaaa gttatgttta ggccaggcat 57240 ggtggctcat gcctgtaatc ctagcccttt gggaggccaa ggtgggcgga tcatttgagg 57300 ttaggagttt gagaacagcc tggccaacat ggtgaaacct catctctatt agaaatacaa 57360 aaattagctg ggtgtggtgg cacatgcctg tagtcccagc tgcttgggag gctgaggtgg 57420 gagaattgct cgaacctggg aggtggaggt tgcggtgagc tgagatcaca ccactgtact 57480 ccagactggg tgacagggcg agactccatc tcaaaaaaaa aagaaaaaag ttatgtttac 57540 actatactat agtctattaa agtgtataag atcattatgt ctttttgcta aaaaatgcta 57600 ataatcatct gagccttcag caagccataa tctttttctt ggtagaaggt ctgcctcaat 57660 gttgatggct gctgaccagg tggtggttgc tgaaagttga aggtagctgt ggcagcagtt 57720 tctttgtttc ttttttcttt ttcttttttt ttgagacaga gtcttgctct attgcccagg 57780 ctggagtgca gtggcacgat ttcagctcac tgcaacctct gcctcccggg ttcaagcaat 57840 tctcctgcct cagcctcccg agtagctggg actacaggtg cctgccacca cgcctggcta 57900 atttttgtat ttttagtaga gacagggttt caccttgttg gccaggctgg tctcaaactc 57960 ctgacctcag gtgatccacc tgccttggcc tcccaaagtg ctgggattac aggcgtgagc 58020 cactgcacct ggccggcagt ttcttaactg aagtttttga catgggttga ctctttcttt 58080 catgaaagat ttttctgtgg cacgcattat gtttgatagc atcttaccca caatagagct 58140 tccttcaaaa ttagagtcaa ttctttcaac cctggccacg gattgatcaa ataagttgat 58200 gtaatattct aaatcttttg ttgtcatttc aacaatgttc acagcatctt cgcctggagt 58260 agatcccatc tccaggaacc actttgtctg ctcatccata agaagcaact cctcatctgt 58320 tcaagtttga tcatgggatt gcagcaatcc agtcccatct ccaggctcca cttctaattc 58380 tagttctctg ctatttccac cacatctgca gtgacttcct ctgctgaagt cttaaaccgc 58440 tcatccatga gggttggaat caacttcttc caaactcctg ttaatgttga tatttcaacc 58500 tcttcttgtg aatcacaagt gttcttaatg gcatctagaa tggggaatcc tttccagaag 58560 gttttcaatt tactttgccc agatccatta gaggaatcac taactatggc agatactgct 58620 ttataaaata tatttcttaa ataataagac ttgaaaatca aatttatccc ttctccatgg 58680 gctgcagaat gggtgttaca ttagcaggca tgaaaacaac attcatcttt acatacatct 58740 ccgtcagagc tcttgggtca caaggtgcat tgtcaatgag caataatatt ttgaaaggat 58800 tcttttttcc tgagcagtag gtctcaatga tttttttttt tttttgatgg agtctcgctg 58860 tgtcacccag aatggaatgc ggtggcatga tctcggctca ttgtaacctc tgcctcccgg 58920 gttcaagtga ttcttgtgcc tcagcctcct gagtagttgg gattacaggc acacaccacc 58980 atgcttggct agtttttgta ttttttgtag aaacagggtt tcaccatgtt ggccaggctg 59040 gtctcgaact cctgacctca ggtgatccac ctgcctcagc ctctcaaagc attgggacta 59100 caggcatgag ccactgcacc gggccctatt tgtttttttt ttgttgttgt tttttaattg 59160 agacagagtc tcgctttgtt gcctagactg gagtgcagca gcgctatctc agctcaccgc 59220 agcctccgcc tcccaggttc aagtgattct cctgcctcag cctcctgagt agctgggact 59280 gcaggtgtgc actaccatgc ctggctaatt tttgtatttt taatagagat gaggtttcac 59340 caccatgttg gccaggctgg tcttgaactc ctgaactcag gtgatttgcc tgccttggcc 59400 tcccaaaatg ctgggattac agctgtgagc caccgtgctt ggcccttttt tgtttttttg 59460 ttttttttca aattgagaca gagtctccct ctgttgccca ggctggagta cagtggcacg 59520 atctcggctc actgcaacct ccgcctcctg ggctcaagcg gttctcctgc ctcagcctcc 59580 caagtagctg gaattacagg cgtgtgacac catgcctgaa taatttttgt atttttagta 59640 gagatgcggt ttcaccatgt tggccaggct ggtctcgaac tcctgacctc aagtgatccc 59700 cccgccccag ccttcaaaag tgctgggatt acaggcgtga gttgccgcac caggcctcaa 59760 tgggttttta atattcagta aaccatgctg taaacagatg tgctgtcaag tagggcctgt 59820 tattccattt ctgaagcata gacagaatag atttggcaga attcttaagg gccctaggat 59880 ttttggaacg gtcaatgagt attggcttta acttacggtc aacagctgcg ttagcctctc 59940 atgagagtca gcctgtcctt tgaagcttta aagacaggca ttgacttctc ccctctagct 60000 atgaaaatcc tagatgacat cttcttccag tagaaggtgg gacatctatg ctgaaattct 60060 gttgcttagt gtagccacct tcatcagtgc tctgagctag atcttctggg taacttgctg 60120 ccgcttctcc atcagcacct gctgcttcac cttgcacttt tacattatag agatggcttc 60180 tttccttaaa cttcatgacc tgacctctgc tagcctcaaa ctttccttct ccagcttcct 60240 cacttctctt agccttcata ccattgaaga gagttagggc tttgccctgg attaggcttt 60300 tgtttaaggg aatgttgtgg ctgatttgat cttctatcca gaccactcaa actttcttca 60360 tatcagcatt aaggctgttt tgctttcttc ttcttcatgt gtgcactgga atcgcacttt 60420 taatttcttt caataacttt ttcttggcat tcacaacttg gctagctatt tggcataaga 60480 gatctcactt ttgcctgtct tggctttcga cacgccttcc tcactcagct taatcatttc 60540 tagcttttga tttaaagtga gagacgggtg actcttcctt tcacttgaac acttagaggc 60600 cattgtaggg ttattaattg gcctaatttc aatattgttg agtctcaggg aatagggatg 60660 cctgagcaga gggagagaga gcggggaaca gccagtcagt ggagcagtca gaacatacaa 60720 cgtttattga ataagttcac tgtcttatct ggatgtggct cgtcatgccc caaaaacaac 60780 tgcaataatg gcattgaaga tcactgatca ctgggcgcgg tggcccatgc ctgtaatccc 60840 agcactttgg gaggccgagg caggtggatc acctgaggtc aggagtttga gaccagcctg 60900 gccaacatgg tgaaacctcg tctctactaa aaataccaaa attagccagg cgtggtggcg 60960 ggtgcctgta gtcccagcta ctggggaagc tggggcagaa gagtcgcttg aacctgggag 61020 gtggaggttg cagtgagccg agatcacacc actgcactcc actgcactcc agcctgggca 61080 acagagcgag actccatctc aaaaaaaaaa aaaaagggcc gggcgcagtg gctcacgcct 61140 gtaatcccag cactttggga ggccgaggcg ggcagatcat gaggtcaggg gattgagacc 61200 atcctggcta acacgatgaa accccgtctc tactaaagat acgaaaaaaa tagccgggcg 61260 tggtggtggg tgcctgtagt cccagctact cgggaggctg aggcaggaga atggcgtgaa 61320 cccgggaggc ggagcttgca gtgagccgag atcgcgccgc tgcactccag acagagcaag 61380 actctgtctc aaaaaaaaaa aaacaaagaa agaaaaaaga aaaaagagat cacagatcac 61440 catagcagat ataataataa tgaaaaagtt tgaactattt caagaatcat caaactccta 61500 cacagagaca cagtgttaac atgttgttgg aaaaatggtg ccagcagact tacttgatgc 61560 agggctgcca cgaaccttca atttgtaaaa agtgcagtat ctgtgaagca caatgaaatg 61620 aggtgtgcct gtgttccttg tcactgtaat gtcggtagga tccgtaagga aaacacttca 61680 ttccttttat tgtgacttta tgttcgccat ctccctctca tcagcagcct ggctaggagg 61740 ttatcaatct agatcttttt aaagaaccag cattggactc cccttttctg gtgtccattt 61800 ccttgagttt ctctgttatc ttcattactt ccttccttgt acttgcttca gcgcattagt 61860 cagggcccag tcaggaaaca aaaaccacac cggcaatttg aatagcaact tgtaatataa 61920 agtgttctta actgtaagag gtagttaact attaaaggga tcacaaaggg gtgacattgt 61980 gatataagaa agatgtattt gggctgggct cggtgcagtg gctcatgttt gtaatcccag 62040 cactttggga ggctgaggca ggcggatccc ttgagctcag gagtttgaga ccagcctggg 62100 caacatggtg aaacctcatg tctaccaaaa atacaaaaaa ttatcctggc gtggcggtgt 62160 gtgcctgcgg ttccagctac ttgggaggtt gaggtgagag gatagtttga gcccgggaag 62220 gcagacgttg tggtgagccg agattgcact actgcactcc agcctggatg acagagggag 62280 actctgtctc aaaaatcaat gtatctgtct gtctgtctgt ctatctatct atctatctat 62340 ctatctatct atctatctag tctctgtccc ccaactttgt ttggcatgta gctcctaaaa 62400 ctcttgaaat ctccaaagtg atgggtgtct ttttgtttgc taaggaggcg actggtggct 62460 ggaggctcct ggacagcctg gggataaggg ctggttgcca ggggacccag ccttgtgatt 62520 agaaggctag aacttgcagc ctttcccatc cacctcctgc gaggcaagag gggatgaagg 62580 ttgagttgat catcaatggc caaagatttc atgtcatgct tatgtagtga agcctccctg 62640 aaaacccaaa aggatgaggt ttgtagagtt tcaggttgtt gaatacctgc aggtgctggg 62700 agggcagtgt accctcccgt ggaagctcca tgccgcttcc ttcatacctt tcttatgcat 62760 ctcttccagt tggctgttca tttgtatcct ttgaaatatc atttgtaata agtcagcaat 62820 tttaagtaaa ctgatttcct gggttctgtg agtcactcaa gcaaattatt gaacctgaga 62880 agggagttgt gaagacctca aatttgtagc caagtcagac agaagttatg ggtaacctgg 62940 tgtcttacca cttgcgactg atctctgaag ttgagggcag tcttgtgaga tggaaccctt 63000 aacctatggg atctgcacta actctggttg gtgtcagaat tgaactgaat tgcaggacac 63060 ccagttgggg actgctgagt attggagaat tgcttggggg tcggcgggag gaaaccacac 63120 atctggtgtc agagctgaag cactgagtgt tgtgaatgag agtggagaga tagagtttgt 63180 tttgccttat gcaagaggac tctaaggagt atagaaagag caaatatgag aagcagctac 63240 tttagaagaa aacataggag gaaagcttcg tgacattgga gttggcaatg ctttcttgga 63300 tgtgacaccg aaaatacaac aaaagaaata aatgataaat tggacttcac caaaacttaa 63360 aacttttgtg catcaaggaa tactaccaat ggcgtgaaaa ggaaatccac agaatggaag 63420 aaagtatttg aaaatcgtat atccgataaa ggactagtat ccagaatata taaagaactc 63480 ctacaactaa gccacaaaac aaaaaaaaac aacccagtga acagacattt ttccacagaa 63540 gacataccaa tggccaagaa gcacaggaag agatgcgcag tgtcactaat catcagggaa 63600 atgaaaatca aagccacaat aaaatatgat ttcacaccct ttaaggtggc tgttagccaa 63660 aacatggata acagcaagtg ttggcaagga tatggagaaa ttggagcccc gtgcactgct 63720 ggtgggaatg taaaatggtg cagctgctgt ggaaaagata taacaattgc tcaaaaaatt 63780 aaactcagaa tgaccataac atccagtgat tccacttcta gatgtatact ccaaagaact 63840 gacagcaggg acttgaacag gtgtgctaca ttcttgtttg tagcagcact tttcccataa 63900 ccaaaagatg caggcaaccc aggtgtccac cagcggatga atgaacagac aaaatgtggt 63960 ccatctgtac agtggaatat tattctgcct taaaaaggaa ggagaggcca ggtgtggtgg 64020 ctcacgcctg taatcccagc gctttggaag gccgaggtgg gcagatcact tgaggtcagg 64080 agtttgagac tagcctggcc agcatggcga aaccctgtct ctgctaaaaa tacaaaaatt 64140 agccaggcat gggggcatgt gcctgtaatc ccagctacta gggaggctga ggcaggagaa 64200 tcgcttgaac tagggaggtg gaggttgcag tgagccgaga ccatgccact gcactccagc 64260 ttgggcgaca gagcaagact gcctcaaaaa aaaaaaaaaa aaaaaaaaaa aaggagattc 64320 tgacacatgc tatagcatag atgagccttg aagacatgct aagtgacaga agccagacat 64380 gaaaagacaa atactgtatg atttcacttt tatgaggtcc ctagagtagt caaattcaga 64440 gagacagaaa gtgggatgga ggttgccaga ggctggggga agggagaatg aatgggaagt 64500 tggtgtttaa tggggataga attgcagttt gggaagatga gatggatggt ggtgatggtt 64560 acacaacagt gtgaatgtgc ttcatgccac caaactgcac acctgaaaat ggttaaaatg 64620 gtaaattttc tgtgatggat actttaaggc atgtatgcaa acacacagaa gcagttacta 64680 ccactggggt tgatggaaaa gaaaccaaga actcggagcg tcctccacac cttgccacgt 64740 cttacgttca ggccttgttg gagagtgtgt gactgccaca gaaacctgca gcctactggt 64800 aacaaaaagg ttcttgccag aaggtgtaga aagagtggat ctgcaggatc agcttactgg 64860 gtagccgaga aacctactag agggtatggg tgggcaggag ctgggtgtct gagaagtttg 64920 ctgaggtccc attgggctag agctggggtg ctggagaaac tcagtacaga gcaggcccca 64980 ctgggcacac gccactggca gctgtgcctt cagaggaaaa agagaccctg gaaccaggaa 65040 gagaagctgc tacctcagca aggcctggca gctccccaca gtgttgtccc ctgtggatag 65100 agcctgacat gactgtattt ggccaaggag aaagactcat aaggcctcgg tccagtatca 65160 cggagcgggg cctggcagga tgtatgcaga gttaagaggc aatacatggg taactggcat 65220 atttttccag attctttgtt ttttttgttg ttttgttttg ttttgttttg ttttgttttg 65280 ttttgagaga gcatcctgct ctgttgccca ggctggagtg cagtggcatg atctaggctc 65340 actgcaacct ccacctcccg ggttcaagcc attctcctgc ctcagccttc taagtagctg 65400 gagatgccca ccatgcccag ctaatttttg tatttttagt agagacaggg tttcaccatg 65460 ttggccaggc tggtcttgaa ctcctgatct caggtgatcc acctgccttg gcctcccaaa 65520 gtgctgggat tacaggcgtg agctacactg cacctggccc atttttccag attcttaaag 65580 cagatcctta ggtctttttt tttttttttt tttttttttt tttacttctt ttctaatata 65640 agcacttaca gtttccctct aagcactagc ttcagcctac gtattttagt atgctgtgtt 65700 ttcattatca tttcatttga aatattgtaa aatttttctt gtgatttcct ctttgactca 65760 tgggttattt agaagtatgt tgtttaattt gcaaatagtc aaggctcctc tgagtatctt 65820 agagctattg atttctaatt taatcttact ttggccagac aagcatattt tgcatgcttt 65880 taaaatttga gacttatggc ccagaatgtg tatcttggtg aatgcactgt tttcacttga 65940 gaaaaaaata tgtatatata ttctagactt cctgagtata gagctttata actgctgatt 66000 aggtcaattg ctagttacca gtgttcttca gattatctga tgcttgtttc tcagatgttg 66060 agagaatggt gtttgctatg gcctacctgt ttgtgtcccc caaaattcat atgttggagc 66120 ttaatctctg gtgcagtggt gttgggaatt ggggcatcag ggaagtattg gctcatgagg 66180 gcagagtcat cgtgaatggg attagtccct tctgccatgt ggggacacag caggaaaagg 66240 acatctctga agcagggagc tagctctcac cagacactga gcaccctgat tttggacttc 66300 ccagcctcta gaactgtgag cactacaatc tgtttataaa ttacccagcc taaggcattt 66360 tgttttaaca tcctgaatga actgaggtgg tgttaaaatc tccaactatg catccaggcg 66420 cagtggctca cacctgtaat cccagcactt caggaggcca aggcgggtgg atcacctgag 66480 gtcaggagtt tgagaccagc ctggacaaca tggtgaaacc ttgtctctac taaaaataca 66540 aaaattagct gggcgtggtg gcaggctcct gtaatcccag ctactcggga ggctgaggca 66600 ggagaatcgc ttgaacccag gaggtggagg ttgcagtgag ccgagattgc accattgtac 66660 tccagcctgg gcaacaagag tgaaactccg tctcaaaaaa aaaaaaaaag agtctccacc 66720 tatgattgtg gaattgccca tttctccctt taattctttc aggttttata tcatgtattt 66780 tgaagctcct ttggttaggt gcatacacat ttatgattat aatggtgtct cgatgaactg 66840 atcatttaac catgatgaat gtattccttt atctcgtaat aattttatct tggactcaac 66900 tttattgata tttatgtagc ctctccagcc ttcttaaaca tgctgtttgg gatgcataag 66960 aaggctggag aggcttatgg agaaacttat gatggtttga cttacagttt ttcaacttta 67020 ccatggtgcg aacgtggtat gtatacagta gaaactgtac tttaagtatg tgtgaaacca 67080 ttgtgtttct cactttcagt acagtattca ataacttaca tgagatagtc aacactttat 67140 tataaaatag gctttgtgtt tgttgatttt gctcaactgt aggctgaagt aagtgttcta 67200 atcatgttaa ggtaggctag gctaagctag aatgttcggt aagttagatg tattaagtgc 67260 atttttgaga tgatatttat tttccactta tgatgggttt gtcaagacat aactccatca 67320 tcattcaagc agcatcagta tgtctttttc caaacagaaa atttcaacct gtgtttatac 67380 tgaaacagca tcttttgtag atagtatata gttgagtctt gctattttat tcattctgac 67440 agcctccgcc ttttaattgg aatattcagg ctatttctgt ttaacatagt tatagatatg 67500 actgggttta gagctactac cttgctcttt gatatttatt tctttcatct tgctttcttg 67560 gcttctttta tgttaattaa gtatttttta gaattctatt ttaatttatg tttttttttt 67620 tttttttttt ttaagacaga gtctcactct gttgcccagg ctggagtgca atagcatgat 67680 cttggctcac tgcaacctct gcctcctggg ttcaagtgat tctcctgcct cagcttccct 67740 agtatactgg gattacagac gcctgccacc acggccggct aatttttgta tttttagtaa 67800 agacggggtt tcaccatgct ggccaggctg gcctcgaact cctgacctca ggcgatccgc 67860 ccaccctggc ctcccaaagt gctgggatta caagcgtgag ccactgagcc cggcctgttt 67920 tgacttttta attgtatctc tttgtattgc tattttagta gttactttat agattctatt 67980 gcacattctt agcttttcac agtctactta gaattaacat tgtttttctt catggaaaaa 68040 aagtgtaaga actaggcaat cctatgggtt catttaccac tttccatcct gtatgtgatg 68100 gttgttagat atttactaca tccatacaca ttgtaaacta gacaatacaa taaggaaatt 68160 tttgctttaa acagccccat gcattttaaa gaaattaaaa gtaaaacaga atcttttcta 68220 tttgcccatg tatttgctat atcctgtgct cttcattcct tcctgaagag ctgagttccc 68280 atctggtctc atttcccatg atcttggaga acttgcttca cggtttttgt agtgcaggtt 68340 tgcagacagc taattccctt tcattttcac ttatctgcaa atctttattt tgctgtcatt 68400 ctttcttttt ttatttttat ttttattttt gagacagagt ctcactctgt ctccccacag 68460 gctacagtgc aatggtgtga tttcaaaact cctgcccaat ctcaactcac caaccttctc 68520 ctcccgggct caaacgattc tcctgcctca gcctcccaag tagctgggac tacaggcatg 68580 tgccatcata cccagctaat ttttgtattt ttagtagaga tgggatttca ccatgatggc 68640 caggctggtc tcgaactcct gacctcaagt gatctgcctg ctttggcctc ctaaaatgct 68700 gggattatag gtgtgagcca ctgtgcccag cctgctgtca ttcttgaacc ataatttcac 68760 tggttataga attctgagtt gtcagttttt tctttcagga ctttaaaata tagggttcca 68820 gtgtctttgg cctccgttgt ttctgtcaag gaatcagcat tcatctagct attcccctgt 68880 agaccacatg ttgtttttcc ctggatgctt ttaagacttt ttatccaagt ttgattgctc 68940 agtacctacc tctgggcaaa aaagcctcca gaaaccagaa acttatctag ttttattccc 69000 ctctgtcagg tgtagactct actccagctt ctacctactt gagatattct atactgactc 69060 caggctgttg ttattttgtt ctttcaaata ttttgtccag agctataatg ttttctgcag 69120 aattgaccag atagcagcta ctctctgtga ccaggagcct tgatcttcca gacttgctga 69180 tgggctcaca aagctcctgc ccgtggccct cagttggcag tggcctctct gccttgaagt 69240 tgccatgagt gtgtaaaacc tacaggctca accttcctca ttagtacagt ccagaaaagt 69300 ggaattcctg gtctgggtgg ctatggtgcc ctagaccact ggctagacca gggtggtgac 69360 tgccagctgg ccgaatgtgg ggtctccagc ctagcaccct tggactctac cccaggagtt 69420 atggctgttt cagggccagg ggcctggcct cagcccctgt cccccttctc ttctcctcaa 69480 gttgcccagc atcaggtccc aaccagcatc ttttgcagac agggtgggtc ggctcctcac 69540 tagaggggca gggttgggcg ggaagcctgt tgagccctcc ttcctgtgca gcccacagcc 69600 ctggggttag ctccagaggg gtgcagaaag gagcccccaa aggcagaaac tcacccttct 69660 ctctgttctt gtgcttccag ggataaagga gaggtggtcc tagctggggg gctaccagtg 69720 gcatgcagga ggcccacatg accactgttt gctggggcct ttccttctct gtgagagaga 69780 cgagagagag gagagagagt gtgagtcagg gtagtgtctt cttccagtaa cgcagacttc 69840 tgcacgtgtt ctctaggaga aatcccgtca ctcgctagag ctctagatct ggaagaagct 69900 ctgcctctct tctctcctcc agtgcagtgt gtgtgtgtgt gtgtgtgtgt gtgtccccac 69960 atgcattaca cccttctaca gaggaaataa ttcccgtcca agtgcaaagg ttgggattgg 70020 agcaggcagc atgtgggcta aaggagcaga gaggaggaaa cgggggcggg ggtgagggtg 70080 ggaacaggag gtgggtagat gccacgaggc atgccttcca caactagaag ggctggtgga 70140 gatgaccaga atgctccaga cagacctttt atcaaacttc caaaattcaa tcttgtttca 70200 tgaagcctga ggaccctgca gagtgaaaga caaggaaggg ctttcctgca ggggggtgtg 70260 tgtgcctgtg tgtgcctgtg tgctgtgtgc ccccatgtgt gtgcacgtgt ggacctgtgt 70320 ggtgtgtgcc tgcacatgtg tgcacgtgtg gacctgtgtg gtgtgtgctg agtgtgtata 70380 tgtgtgtgcc tgtgtgctgt gtatgcactt gcacatgtgt acacagatct cattttcctt 70440 ttttctggct tactaagtgc cagaaagaat ttccgtgagc ctctccaccc ttcccaaggc 70500 tgcacatgga gggacttgcg caggcacatg tgcgcgtgca cacaacacac acacacacac 70560 acacacacac acacacacac acacacgagt caggggcgag cactcctgtg gattgtacct 70620 aggcctggca ggaaaccggg ttctgggaaa ctgtaggccc cacctttggc agaaaaccat 70680 gtttttgttg ctgctcgttg aagggaacat taagtggggc tggggacagt ttatgttgag 70740 aagagcaaat tttgcctatg gcactgggga cattgagtgg ctcctgtccc gggctctgga 70800 gggcttggga gacacgtctg cagctctggg catctctcaa ggtcacgggc ggccacactc 70860 aaggttaggc cctcctctgt gtgagctgcg gtcagcagga aggctgacct cagaggcggc 70920 cccagggccc ttggaggccc tgcccctgag acatgggcca aggtcagaga gccgagaagg 70980 ctgctgctga ggactctggt tggcgcccag cccagcggcc cttcaggcgg gccctgtgca 71040 ggggctgatg aagtcagctg ggaaatctgt gaaataaagc acaggtcccc caggcttgcc 71100 cagagccccg gcatcagatg aggtgcagag aagggaactg agctgccaag tgtgaacagg 71160 agagaggagc cccaggacca cacaggggcc ccgacatggc aggtgcttgg tcagcagcgg 71220 tgctgccctt actgctggac gtgggaaaat gcactgacac ttgctgacca gagccggggt 71280 gagcatctgg gtgaccctgc agatgagaca aaataagggc tgccgtgggg gaggggccct 71340 tgccgggcca ccctgctgag gccctgtgtt actgtcctgc ggctgtcata acaaaggacc 71400 acaaatgagg tgactcaaaa catccgaaat cggccacgtg cggtggctca tgcctgtaat 71460 cccagcactt tgggaggccg aggcggttgg atcacgaggt caggagatcg agaccatcct 71520 ggctaacatg gtgaaacccc gtctctacta aaaatacaaa aaaaaaaaaa aaattagccg 71580 ggcgtggtgg tgggtgcctg tagtcccagc tgctcaggag gctgaggcag gagaatggca 71640 tgaaccttgg aggtggaggt tgcagtgagc cgagatcgcg ccattgcact ccagcctggg 71700 tgacagagca agactccgtc tcaaaaacaa aaacaaaaac aaaaacaaaa acatccgaaa 71760 tgtcttccct aaagtttctg gagccagaaa tcccagaccg aggtgtctga aggttcattc 71820 ctcctggggg ttccgaggga gactgtccca tgcctttctc cgagctctgc ggcggccagc 71880 aacccctggt attcctcggc ttgcagctcg gcctaccccc cacctggcct tcaccctgtg 71940 tctcttcttg tgtctctgtc caaactgccc tctctgttgt ctttttaatt tatttttagg 72000 gacaggttct cattctgtcc tccaggctgg agtgcagtgg cgtgatcatg gctcactgca 72060 gcctcagcct cccaggctca agcaatcctc ccacctcagc cttccaagta gctgggacac 72120 aggcgcacgc caccatgcct ggctaatttt ttaatttttt tgtagagacg agggcccagg 72180 ctggtctcaa actcctgcgc tcaggcaatg agactttgcc tcccaaaaca ctgggattag 72240 agacatgagc tgctgtgccc agcctacctc tgtcttataa agacacctgt cattggattt 72300 agggcccact ctgattcaat atgccctcaa ataacccaat tacatcttca aagaccctat 72360 gtccatataa agtcacattc ataggtactg gggggtcagg acttgcatat gtcttttggg 72420 ggaacacaat tcaacccaca atgggtctca cccacagaac gaacggcctc tccagggtgt 72480 gcgcaggtgg gtgaggggcc caggagaggg acctgcgtgg caagagggct tgtgttcacg 72540 tcagagattc cagaaggaga ctggatgggg tggctgcatg gagcaagggg ctacagccac 72600 tgtctccaag tagttggtgg gttgtctggt agaaagggag catttatttt gagttccccc 72660 aagatatgaa gctagtacca ggtacctgga aggtgctagc gagtagagct tgactcttta 72720 cagaaagagg tgtttttctc acaatgttca cttgaggacg gtggaacagg ctatttcaca 72780 aggtagtgag ttccccatgc ctggaagcat tcaagcaggg gccatgtggg agttgttcag 72840 gagtgcatag aagggacctc agaggtccct gccaatacca tctttgcttg tcttatttta 72900 cgacaacttg aatttcagaa tgtaatgtta ttggggatat gtctactaga ggggcctcca 72960 gcatcaggcc ccacacacta tgcatcattt ttagggcagg gaatgagagc aggctccatt 73020 ctttttggtt gtctgtgagg accaggaggc ttgctgctga ggcagcttcc tgtggaaaca 73080 gtgtctcagc cccgcaatcc attcatcgga gctccaacat cttaatgaaa cactgtgtca 73140 gatgggttct gggcatgtgt gtgcagattg tcacaagtcc atgagaatgc acacacgcac 73200 attgcatgtg tgtgcacaca tgtatgcaca catgcacaag aacacgaaga cccgaggcag 73260 gtatagtccg tgagacagat ccctctaggc tgaaagactc cccacaaggg tccctagaac 73320 aaggctccag cctcggcagt ccctcccact tctggtggga ggatctccac agagaagaag 73380 ggtcaagaag cacagctctt gatgctcacg gtgtaccaag ctctgcttta agcttgtgtc 73440 ttatttttta cttatttagc aaatctgtcg ctcttgtttt gtgccagatg ctgttctcag 73500 cactttacaa atattgatgc atgtttgttt catgacaacc ctgtgaagta ggtagtgtta 73560 ccccgtttta tagatgagga aacaggcgta gagggataaa gggacttgcc caaggtctgt 73620 ctctacctta cacgcacatg aacgctcact catgcggcag gcgctagttt ccctctgatg 73680 tgagtcaggc cttgagctgg ttggggtctg ggtcccactt tggttgtgtt ttgctgtggg 73740 caccaaggaa gcttctagca gcctcatctc cctggtatga cctagctcca gggactggat 73800 ttccccaaat gctcctgccc agcctggagc ctcctttcca gctgggggag ggctgaacga 73860 cccctcactc ttggaggctg ccggagcccc tcctgcctgc atgcggccgc tgccgggtgg 73920 acaggcctgc ttgtgggttg aggctcccag cagctggggt ggatcatttc tcctcccaag 73980 aagctttggg agaagcagct gagggggcca gcgtcctcct gaggccaatt ccctgcctcc 74040 cccagcgcag gcgcgaagcc atctttgctt gtgtgtttgc cacagacagt ggagggcggt 74100 gcaatcgtga cgcctgcttg ttgcactttg cgtccttgag gacgttgacc cctggccggt 74160 gctgggcgct tgctcttcag tcatcttgcc ctgacctggc gtggcaggcc cgagcactgc 74220 tcttttacaa ggaaacaggc tcagaggcct tgagtcactt gcccgggctc ccccagccaa 74280 taattggctg agccaggatt tccatccagc tctgtgactc cagaagtcca agttcttccc 74340 atcacgtcag ggccaggaaa ggattagaat gcttttctac gtgccgatta tttggatgat 74400 ctgtgcagct tagctcgttg tagttgctca ataaaaatgt ggaatgaatg ggcctatatg 74460 tcccattgtg tgactcagag ccaatgactc tggctgatcc tcctgttttc attccgtggc 74520 ccagcatctc cctttggggt gtgtgacctt ggaagcagtg actctctcca tcccaccttg 74580 aatggtgtct gcgccgcagc aggggagcag ctggggattg ccagcgcctg ttgctggtgg 74640 gctgtgcgcc agatcccgtc ttggatgtgt gggtgattgt cagccacatg tgtgtgaagg 74700 gctgtgcgtg taggatttgt gcaaatgtgc ccctccctgc tgccagccca tgggaggctg 74760 tcaagattct gcccctgcac attagcccac actctctttg tggcccactg ctgtggctgt 74820 tcccttgtgt cacgtggctg caggcacagc ccccaagtgg atggggatcg tgggctgaat 74880 gtgcatcaga tgctcctgct tcttggtggg tggagaccct caacccatgc accgtggctg 74940 ccgcatctga aaggccttcc atggtgaagg acttggacct gagcaaccct ccgcagaggt 75000 cttagaagtg ctccctggcc gggcgcggtg gctcacacct gtaatcccag cactttggga 75060 ggccgaggtg ggcggatcac aaggtcagga gatcgagacc atcctggcta acacggtgaa 75120 accccgtctc tactaaaaat acaaaaaatt agccgggcgt ggtggcgggt gcctgtagtc 75180 ccagctactc gggaggctga ggcaggagaa tggcgtgaac ccaggaggcg gagcttgcag 75240 tgagccgaga tcgcgtcact gcactccagc ctgggcgaca gagcgagact ccgtctcaaa 75300 aaaaaaaaaa aaatgaagtg ctcccagctc ttcctcctgt ggtgaggttc tgagtttcca 75360 tcctcagaag aaaacctggc tggggagggc atctctagac ccggacataa acgccaggag 75420 accagggctg ccctctcagg tgaccaatca cagagactca gggaaagtca cgtttggaag 75480 aggcgacact gtgtctcagc ctcattcatt tctccatcct acagacactg cctggtgccc 75540 agcccgcacc gcgaggcttc ctaagcagct ctgggcaccg tgcacctggc atggcctcca 75600 gccccatctc cctgccttgg gagacccggt ggggactccg ggctgagctc ctgtggctgt 75660 ggaaccttgg tggtttattg tggtggctga gaacagggac gtggggttgg acgggttgag 75720 tgtaactccc agtggctccg tgaactgcct gggagccttg ggcagctctt tctcactctg 75780 tgcctccgct tcctgatgga aaaatggggg ccagggggga gcgaccttga aggtattcgt 75840 gggaaccaag cgaggtgata aatgtagtgt ccttggtaga gaactggaca cagagtccac 75900 ccccatgaag ggggctgctc ctcctccttc tatgtttcct cttgttctta tttctcctct 75960 tgtatcttct cttcctgctt tccctccccc tcccctcccc ccccacatgc aggcacactc 76020 catttggtgc cccaactgcc tttctccatt gtccttctgt aagtggttct ctaagtggga 76080 actcaggcct ggaaagggtg ggcaccctgt ctggtgggct ctggcaggcc aggcgctgag 76140 cagcctcagg agacacaacc ctaggaaaag gctcatgcag gctggctgtc atgacggact 76200 gttggtggga gaggggaagg cgccgtggta ggggaagctt tggaaacatc cactagtggc 76260 cttatttatg actcaggaca cctgccaggt cactagaaca cagctgagga agctgtcggc 76320 cagacgtcca gaagcatcaa cctggtggct gggctgtggg gggacctctc tggacaggca 76380 gacaaggtgt cggaggaagg ggctgacact cactcagtgt ctgtcatgca ctgagggcac 76440 aaagggcagg atggagagct ggcccacgcc acctgtggaa tcttccaggt gtgggggcag 76500 atggggaagc aagggggctt gaagacacat gcgctcatta aatgtcctta aatcccaaga 76560 agaagaacaa ggacacatcc acaggggcag ggctgaaagt ctgatgcatg gtgttttggg 76620 gtctgctcct gctgcaacag ctacagtggc tccctcttac ctttctcttc cctccattct 76680 gttgtgaaaa tgttcaaaac acatggtcaa gttgaaagca ttttacaggg aacacattca 76740 gccatcacct agattctacc actaacacca agctacacct gctttatcac ctcaccgtcc 76800 atctatccct ccttcgcctg gccatgaatc cattttattt ttattttttg gtgcatttca 76860 aagtaatttc aggtcatcct gattatctct ggaatcactg tcagaaattc cctcccttcc 76920 cctcccctct cctttccttt ccttttctga gatgggatct tgctaggtca cctaggctga 76980 agtgcggtgg tgcagtcata gcacactgca gcctccaact cccgagctca agcaatcctc 77040 ctgcctcagc ctcctgagta gctgggaccg caggcatcca ccaccacacc cagcttcatt 77100 ttcaaaattt ctcaccaact cctcactcct tgtattcacc caggaccact tctcacaaag 77160 ccagggtgct gcaggagggg tcagaacccc aagccctaat cctggctctg tcattaacac 77220 tgtgcgaccc tcagcaaatc attttgcctg tctaggtcct gttttcattc ctatgaaacg 77280 agggcgttaa actgtatgtt ataaataatg agggctacca gttaccaagc tcctatttta 77340 ggccaggcac ttttcacatg ttattatgag tcctttcaat ctaggtattg ttctcaatgg 77400 acagcttagt caacggaagc tcagagaggt ggtgtaactt gccaaaagtc ccactaccca 77460 gtgaatgtcc ccacggggtc tgcacccagg agtctgacac agagcccagg cctcagcacc 77520 tggcgatgtt ttgggggtgt gagcagccca gcctactctg ggcacgtgtt tacttgctgt 77580 tccttctgcc tcatgtttgt gtttgtcccc tctgaagctc agactgttat tttccagttc 77640 caaataccaa aactggctag gcacggtggc tcatgcctgt aatcccagca ctttgggaga 77700 ccaaggcggg tggatcactt gaagtcagga gttcaagacc agcctggcca acatggtaaa 77760 accccatctc tacaaaaaat acaaaaatta gccagacatg gtggcgtgca cctgtagtcc 77820 cagctactca aggagaaccc agctacccag ctactgaggc acgagaatca cttaaacctg 77880 ggaggtggag gttgcagtga gccgagatcg caccactcct ctctaggcta ggcaacaagt 77940 gtgagactct gtctcaaaaa taataaataa ataaaataaa ataaaaatta aaaccaaatg 78000 ccaaaaccaa cccacaaaat aaaccttggt taaagtagcc tgttcatttt gctttaacta 78060 tgtatattgc accagattct gccaggggct cagcgtataa agatgagacc cctgccctgc 78120 cagacaggtg ggatgatggc cataccttga gttagtcaag gcaccatctg gctgtgtaac 78180 aaaagctaaa acatcagagg ctgagcagca ctcggaccca cgtcccagtc caagtgtcag 78240 tcgttatggg ggcccaggac agcccggacc tagttcattc ctttggtgca tcctcgacac 78300 acagcttcca tctcttgagc tgagatggtt ccagctcctg ccgtcatgtc tgcactccag 78360 ccagagggaa gggaagaagg gagaggggaa agggcaagtg tccctcttta tttttaaggg 78420 catgacctga aagttaaaca cttcagctcc ttcccactgg ccagaaccca gttgtatggc 78480 cgctcctgtc atcagggagg ctgagcaatg tattcttcag ctgggcttcc ctgtgcacaa 78540 ccaaaacttc agttactata gaaaaaaggg agctcagata ttggggaaac aactagcatc 78600 tgtaccacat gcactgatag ctctctttgt atgaacagag ctgtggcagg ccctatgcca 78660 gggagaaagt aagattggaa aagagcttac caaggaggtg gcatttgcac tgtgcttaag 78720 gggcaagaaa aacgtcttcc aatcaggagc cacaaatgct tggctgaagt gctactgctc 78780 tttcatcctg gagctggaac agacgtcacc agtcaatcat gatggctgct gggtgcactg 78840 gctaacatct ataatcccag cactttgtga ggctgagggt gggaagattg cttggggcca 78900 ggagtttgag accagtttgg gcaaattgca agaccctgtc tctgcaaaaa aatataaaat 78960 gtagctgagt gtggtggcac ctgtagaccc agccccagct actcgagagg ctgagatggg 79020 aggatcgctt gggcctagga gttcgaggct gcagtgagct atgattgcac cactgcactc 79080 cagcctgggt gacagagcag gacctgtctc taaaaacaat aaaataaaat caaagtttta 79140 aaatggaaaa aaaatcatga gcacataact ccagatgtat cctcaagata gcaaacccgg 79200 gtgggcgcag tggctcatgc ctgtaatcct ggcactttgg gaggccaagg tgggtggatc 79260 acctgaggtc aggagtttga gactagcctg gccaacagcc ccatctgtac tacaaataca 79320 aaattagctg ggcatggtgg tgggcacctg tgatcccagc tacttggaag gctgaggcag 79380 gagaattgct tgaacccagg aggcggaggt tgcagtgagc caagatcaca ccattgcact 79440 ccagcctgga gaaaaaaagc aaaactctgt ctcaaaaaaa aaaaaaaaaa gcaaacccag 79500 ggccaggtct gtagccacat ggccaccttc ttccctgagc atggaggcag cctcagaaac 79560 ctgccccaca tcacatcagt gggcagttga ttgggtcagc ctgccagttg aaccctattt 79620 gccacagtca ttctccatag taaggggcat tctagacata ccccccttcc cagggaagaa 79680 taagccgtag ctgcctgagc gttttatcca gtggtgtgca tgtcttttcc caactctgtg 79740 tttagtgatg tcctgtttgt agcttgaaat ttgccacagt gggtgtgttt acaccacagg 79800 aattggcaaa cactacatat caggccttac ctcctgctcc ctactagggt aggttgtttt 79860 ttttttgttg tttttgtttt ttgtttcttt ttttttttga gacggagtct cgctctgtcg 79920 cccaggctgg cgtggagtga tgcgatctcc gctcactgca agctccgcct ccctggttca 79980 caccattctc ctgcctgagc ttccagaata gctgggacta caggcgcccg ccaccacacc 80040 cggctaattt tttgtatttt tagtagagac ggggtttcac cgtgttagcc aggatggtct 80100 cgatctcctg acctcgcaat ctgccctcct cggcctccca aaatgctggc attatgccac 80160 tgcgcccggc ctagggtagg ttgttagaaa tgtaccagcc tgccagtttc agccttgttt 80220 gtctttcatc cttttttttt tttttttttt ttttgagacg gggtctctct ctgttgcccc 80280 ccaggctgga gtgcagtggt gtgatcctgg ctcactgcaa cctctgcctc ctgggatcaa 80340 gtgattctcc tgcctcagcc tcccaagtag ctgggattac aggtgcccac caccacgtcc 80400 agctaaattt tgtattttta gtagagatgg ggtttcacca cattggccag gctggtatcg 80460 aactccttac ctaaggtgat ccacccgcct tggcctccca aagtgctggg attacaggcg 80520 tgagccaccg cactgggcct ctttcgttct ttcttaatga aaatcttcct gaaagatttg 80580 cctactgatg tctgtgtcaa taggtactgc ctgcgggaca gagcctgccc tccttttgaa 80640 ggtctttctc tgtctgggtg accatctgca tgtcactccc tgctgctcag aactaaagat 80700 gtagctatgc ctggggtagg ttgggaaaac ctgtgggaat cacagagctt gctgtcatgc 80760 tgtgttctgg atacctgaag cttggcaggc aggtgggatc gagggtgggc attaggaaag 80820 tgatgtggct ctataggaag gggacatagg tcctgagatt ttaggtcccc aattggacaa 80880 agctgttttt tttttctgga taaatgttct agcttattca taatcgagtg gtcagttttc 80940 ttttcttttc ttttcttttt ttttttgaga tggagtctcg ctctttcgcc caggctggag 81000 tgcagtggcg ctatctcggc tcactgcaag ctccgcctcc caggttcacg ccattctccc 81060 gcctcagcct ccggagtagc tgggactaca ggcgcctgcc accgcgtccg gctaattttt 81120 tgtattttta gtagagacag ggtttcaccg tgttagccag gatggtctcg atctcttgac 81180 ctcgtgatcc gcccgcctcg gcctcccaaa gtgctgggat tacaggcgtg agccaccgcg 81240 cccggccaag tggtcagttt tctcagctgc cgggtcttgc acaccttgct ggctctggag 81300 accatatgca ccatgtagac cccatttgtt tcctaccctc agtgttgggg gaggggccaa 81360 gggcctgtcg atgtgttgac acctggccat tcactggcct tgaatgtcca cattcacctc 81420 cttgaaatcg atgccccgta tcggaggctc catgtggatt tgggggcaga ggcctgtact 81480 ccagatggtg gggtggcctt caccaatcag gcagattccc tgccctgccc tgccctttgg 81540 gctctgtagc tccagatgtg tgctcaagat ctgtggccac atggatggga caagccacag 81600 agactcagac tccgtggtcc ctgtgaccag agtagccgtg gccctgtctg ggaatgttcc 81660 caccctgttg ctgaaggtga gaaatttctc tgtgctggag aacagctgtg ctgagaagtt 81720 ggcccatctg gcttgcagga ctgctggggc aagggaggtc tgctgccggt ctcttccttc 81780 ctcctctgac tgggtgctcc ttgtctaggt tccttgcagc aaaagaattc tctaatttat 81840 tttgttccct tattgagtct ctactccatg aagcccacct cctaatccca gctgactggc 81900 tcccacctcc tcaagaggaa ggccaggggc agacgaggct gaaggaggct gactcccctg 81960 tgccttcgca gtctgagctg atgctgctgt atgttcacag ggctccttca gcttttaaaa 82020 aggcttcaac acgttcgtca cacgcttgtg gctctcctgg atgccacact aactcagtaa 82080 ggcctgagtt agaggctgtt cctgaggctg tgaaaataga agaagggtcc agaggagaat 82140 cccttcatct gacgatccca ggaaggcttc ctagaagaag cagcctctga gctgagacct 82200 gaagacagat caggcctgag tcaggccagg gagggtgtga ggggcccacc aggcagaggg 82260 aacaggatag ggcaggcaca gaggtctggc acctggcttg tggggaagtg tgagcccctg 82320 ggcatgacca aggcggggag aagtggcgtg agaggaggca gatgtggctg gcaggagatc 82380 ggcggccccg gccttgctga gctccactct gtatgcacca ggtgacagag gctgcccagg 82440 acggtgggca gggaagtgac aggtcacatg gtcatcccac caacagccgg gagtccagct 82500 tggggggacc caagaccctg gggaaggcac gagtcagggg cctgctagag ccaggagcta 82560 gtgggagaag gaaacagtgt tgcttatgaa ttataaacag acactcccgc aactttctct 82620 gacgtgatac aatctcaaag tgggccaccc agaggtggga aggtgacttc tggctctcca 82680 ggccttgggc ctgtcttttt tttttttttt tttttttttt tgagatggag tctcactctg 82740 ttgcccaggc tggagtgcag tggtgtaatc ttggctcact accacctctg cctcctgcgt 82800 tcaagcaatc ctcctgcctc agcctcctga gtagctggga ttacaggcac ctgccaccac 82860 acccggctaa tttttgtatt tttagtagag atggtgtttc accatgttgg ccaggctggt 82920 ctcgaattcc tgacctcagg tgatccgccc accttggcct cccaaagtgc tgggattaca 82980 ggcatgagcc actgtgccca gccgagccca tcttcaagtt ctccctggcc ctcagtgttt 83040 ctgtattagt tcaccctttt ggctccctgc ttttaagagt ctcccttaag actgtcccca 83100 agtggacagg tccccagaac caaggagcag ccttaggagt ccccagttac agacactcca 83160 gggggtccgt gtggccctca gcctctggcc tggttccggc agccttggtc ctttgtgctg 83220 tctctcacat agcctggcca gagctggcca ggtcccttgg ctgggccgag tcatcgtggc 83280 cagtgactca tgcaggggga gaaaagtgag gagggggaac agagtgcgag ggggactgtg 83340 ttaataacaa acccattagg tccctgaggt cacttcacag gagggacaaa tggttcattt 83400 aggttgatct ggctgccggc tggcttccag agacactcag ggtggggaag atttcattat 83460 ctggggaaag caataccaga ttgtctggag gggcccagcc agcgcacccc gcgcttcctg 83520 tctgcctccc acgcagagcg ttctgttccc aaggcggcag gccaagagcg cgagccgagg 83580 ctcaggtgca aagaggggtg cggcatgggg gcactgcagg gcacggggtg catgcatttt 83640 tatttatttt tttactgagt gttagggtaa tttgttaatg gggtatattt ggtgacataa 83700 aaccttctgt cgattcatgg cagtctggaa cggagtggaa gcgtcccact cctggggaac 83760 ccccacacac atttggctgt gaacgtcggt gcctttgcac tggagcctct ttggagtgtg 83820 ctgggcagag cggagaggtt cctcttctct cttctccatc atcctgtgga ggtgtcaaca 83880 tgtagccaga gatggtcagt ggcagtgagg agaggggggc aggaagagac cagggctggg 83940 ggcttgccag cccacagttc tacccctgaa cacccatggc ctccctgttc aggtcagcga 84000 ggctgggggc agagacgggc aggggtcccc caatgttggg catctccccg ctccctcata 84060 ctctggattt gccctctgga gaaagctctg gagcacccag aagtcctggg gctgctggct 84120 gaggtgggga gcagagccca gctgtgcctg gaggctcccc acttccactc agcttccagg 84180 gacagtctca gctgtgcagg cccaggccgc tgaggctggc tccagaaatt tcttcacaac 84240 caccactgga tggaaaacca gttctctaaa gggccccaga gccagttttg tttcttcttc 84300 cacaggttcc catagttaga gcatcgggtc tttgttagag atgcagaaga gacgatgtcc 84360 ccagccctta tgtggttcgg tctccactgt ggatgttggt gatcttagtc tccttctcaa 84420 aaccaagagg gctgatgccc cacattccag gcccccagaa agagccgcca cccacccaca 84480 ccgctacatc ttctttccac ttttctgttc cggaaagagt agagtggata tgcgctcctg 84540 tagaaatcca tctacagcct gactgcagat gtattttgct cccttattga gtctctgctc 84600 catgaagcct gccttgtttg tacctctttc tctctctttc tctctttctt ccctctcttc 84660 cttcccttcc gttcccttcc tttttctttc cttcctgtct tattctttcc tctttctttc 84720 tttcctctct ctctctttcc ccctttctct gtctttccta tcttttcttt ctctctcttt 84780 cctctttttt gaacagccaa agatagaatg aatggcatag gtaggtactg agctccctgt 84840 aactggaggt gttcaagtgt agggtggatg ggcatttata gggcaggcat tgaggaagga 84900 tctccctggg attgtggatg gcaggacagg ccctgtggag ccttctgagc gggtgcagaa 84960 gagggagggc atgttcctgc tccctgccct tcccgggttg ccaggccgcc actcccaacc 85020 tccaccctct ttccttccac ctgctgggcc ttacgggatg ggcagaggca ttgttagaac 85080 atggagccgc ggtccacaga gggccagcag ggaggagagc tccctgggga ccacgtcgcc 85140 tcagtcactg tggtgacttt gaaaataaat gctttcttct ctgcttgagt ccctgttgtt 85200 cctgctgacg tggaactagg gcaggctggt gactcagccc tcatccctgc actgcatcgg 85260 tggcaagttg cctccagcct cagaccccac agagcagggt gccttcttca gaaaaacagt 85320 agggaggcca ggacaccaag ggccccaggg acagcctgtt tctcctggct ggcatgagtt 85380 ctagccaagc ctcctggtac cctgggggtg aggaggtacc agctgtgtgc tttagtcact 85440 ggctgctttg aggctgggtc ggtgccaggc tggccactcc ttcttgtccc ctagtgtgac 85500 tttgcagagc tcccggaagg gtcagagggt ttttttccat cactggtgtc catgggatac 85560 tgtgtcccca tctcattttt gtactccagt ctcagacggg tgctaggaag ttggagactt 85620 tagccatttc acgactgtgt cttgcggggc tggagtagga acaggagtag gaggaacgct 85680 ctggtcatgg gactgtgtga agagagaagg atcaggaaga aaacatgagc tatcatgtct 85740 gggttatacc tcagcagagc cgctggtggc ctcccaggca tctgaattta ctaatcacaa 85800 agctcaccag gtgtgcaaat aaacaaatgc tgttcaggag gcacagccag ggttctgctg 85860 gagagggatc atcttggagg ggtcatactt tccacccagt ccttcagtcc ttctgtcctg 85920 tgtgtgtgca gcccctgacc accaccatcc ctgcccctgc cacttgctcc cagggttcca 85980 tcaggttgga tgttattgca ataaaatgta gcaacagaag gtccaggcag tgctgcagtc 86040 cctggtggta tcatcagagc cagcaggcag cagggctggg gaactccaag ctgattcagt 86100 cccaagtgcc ggagcgggga gctcggatga ggtgggggtg gggaaccggg gagccatgga 86160 gcagagcatt tgctgtgctg aaggccagga gcctccttgg gagatcatga atttagaaca 86220 ctaatacttt gtttaaaaag tcccctgcct tggagataag agctcaggcc gctgtggtca 86280 ggttttgctg taaatgttct gcacaaagca ggctgggggg atcactggga agtctgggga 86340 acagattggt catgtgcttc tttgagtgaa accttatggt tgcattgaag cggccaggca 86400 gagggtgtga tggggtgtgg tagctgcaca ccggctcagt caggctgaat ggggaaatgc 86460 aaactcaggt ggcctgaaag agacttagtg gtccacagcc tggtggctgc tcccagtaca 86520 ggtgatgtaa agagagaagg ggttccgggg gcttggccca ggtggaaacc atgcactgtc 86580 tgtgatcctg ggcatgtcga ggctggagca ggtctgcttg gtggctggca gaacgcacat 86640 gaagaatcca tgtgtgttct gaacgtcccc tctgcccctt tgggctcatg ccccatcagg 86700 agtctcccga ctctgccatt ctgcaaagga aactgcgctt tgtcattgca caggatcgaa 86760 caggtgtgtg tggagtccct aaagccactg tctcaagggg tctcatggga caatgggaga 86820 gttgctgtga tgtttaagac taaagtgatg gctgggcgca gtggctcacg tctgtaatcc 86880 cagcactttg ggaggctgag gaggatggat cacttgaggc caggagttcg agactaccct 86940 ggccaacacg gtgaaacccc atctctacta aaaaaacaaa aattagccgg gcatggtagc 87000 gggtgcctgt aatcccagct actcgggagg ctgaggcagg agaattgctc cgatctggga 87060 ggcggaggtt gcagtgagcc gagatcacgc cactacacta cagcccgggc gacagagtga 87120 gactgtctaa aataataata atgctaataa taaataaaat aataataata aaataataaa 87180 agcaaggact tgaacaaata tttgcacacc catgtttgta gcagctttac tctcaattgc 87240 tcaaatgtgg aaggaatgga tatacaaagt gtgtgtacac acagtggaat atcattcagc 87300 cttcaaaagg aacggaattc tgtcactaca tgtgaacctt gaataatgaa ccttgaagac 87360 ctcatgctac gtaagcctgt ctcacaagga caaatattgt atgatttcac ttatgtgaag 87420 tcaaattcat agagaaattg gaatgacggt tgccagcagc taggggaagg aaggatgggg 87480 agttattgtt taatgaggac agagtttcag tttgggaagt tggaagaagt ttcggaggtg 87540 gatggtgttg atgggtgtac aatgtgaatg tacttaatgt cactaacatg gaaacttggt 87600 taaaatggta aatttgtctt ttttgttttt gttttttttt tttttgagac ggagtctcgc 87660 tctgtcgccc aggctggagt gcactggcgt gatcttggct cactgtaacc tccgcctccc 87720 aggttcaggc gattctcgtg cctcagcctc ccagagagct gggattatag gcgtttgcca 87780 ccacgcccgg ctgatttttg tatttttagt agagacaggg tttcaccatg ttggccaggc 87840 tggtcttgaa ctcctgacct caggtgatcc acccaccttg gccttccaaa gtgctgggat 87900 tacaggcgtg agccatggtg gctggccaaa aatggtaaat tttatattac atatatttta 87960 tcacagtaaa aatgcattgc tctattagaa aaatgataga tttttacaat atgaattaaa 88020 ttacaagtta tgaaggaaaa attaagcaaa acattaaaaa attacttata agtaattata 88080 tttaaaacaa aagataataa atacacaact ttcatcacct cttaggtttt ttgcaacatt 88140 taactattgt ctgtcctgtt gcggttatgt tcttgaggtt gtatttgtat gatagaaaca 88200 ctatattcgt ggtgactaaa catctcttct cagtctcacc tccaatgatg tcatacagat 88260 aacttgaaat tggccggctg ggcacgatgg ctcatgcctg taatcccagc actttgggag 88320 gccaaggcag gcagatcatc tgagttcaaa accagcctgg ccagcagggt gaatcctcat 88380 ctctagtaaa aatacaaaaa ttagccagga gtggtggcgg gtgcctgtaa tccgagctac 88440 ttgggaggct gaggcaggag aatcacttga acctgggagg tggagtttgc agtgagccag 88500 gattgcccca ctgcactcca gaccgggtga cagagtgaga ccctgtcaaa aaagaaaaga 88560 aaagaaagaa attggccaag gcaggaatat tgacaccaca ggaataggca agcgctacaa 88620 atcgggaaac tgagtgttgt tgcttttgct ggccccaggt ggccggttgt tgaccgttaa 88680 ctggcacact actggaggag ggaggttcag actgattcgc agagagacta gaggtagaaa 88740 cgcaccatgg tttggatgct gagggtgagg gaaagagagg agtcaacagt ggtgcccgga 88800 gacttggctt gagcaactag gtggatggta gcaccgtttc ctaagatgag gggctgtggg 88860 aacttgaggg gctgtggaag gctctgccac tgacggaccc agggctcggc agctctggga 88920 ggcctacttt gtgtcaggcc acgcagagat aagaccatct gggccctgcc cttgggaagt 88980 ctctgtctat gaggacacag cctgccacct aatggggtgt cccgtctgga gcctcagtgt 89040 tgctgggaga aagcccctca ccttccttcg ctctccgagc ctcttttgct tccctgccag 89100 ctgagcctct ccatggaggc tgtgcctgga ggggggtcat ggatatggat gtgtgcgcca 89160 aacgctgctt cctcgtggat ttcctcccca ctccgttccc acgctttgta agcttcattt 89220 ccccggggcc tgacctgtgg ggtttctctc cagacctgct ccttcccatt tccagaaagg 89280 cgtgcagggg tttcctatgg ctctcttccc tgtccccatc ccccttccct tgggacagtg 89340 atctgctgga cgggtgggct acccacaggg tttgtgattg cttagacatc tttgctgtat 89400 gaagctttga cctcaaggca tgatgcagat gggaataagg cacgagtttc tcctggctgc 89460 tgtaacaact gtcgaaactg ggtggcttat agcaagggga atgtgtcctc tcacagttct 89520 ggaggccaga agtctgaaat caaggtgcca gcagggccag cttcctctga agactccagg 89580 ggaaaacctt tctttgcctc ttccagcttc tggtggcccc aggtgttcct tggcctgtgg 89640 ctgcatcact ccggtctctg cctctgtctt cacaaggcct ttttctgtgt ctctgtactt 89700 tcttttctgt ctcttagaag gacacagcat tgaatttagg gcccacctta tcttgagatc 89760 cttgcctaaa ttctttctgc agagaccctt aaacagaatc aggtcacatt tgaggttcca 89820 agtgggcata tctttgtttt gggggggatc accggcccac tgtaggtctc gttgtgcact 89880 gaagacgcag gcggtccctt tggccaggcc tgcagtcggt cttgccttct tttgtgaccg 89940 tggaagaatg caccttgctg gatgcacagg cctttatagt tcttttgttc ttgccaaatt 90000 tcagctcagt ttcctctctg ctgccggcgt gcatcttctc tgcccagtgc cccttctggg 90060 actgtgtgtc caggccctga ggccctagaa aaggggggtg gagggcctcc tcactatcct 90120 gtagcaatga ggcctcatta aaatcctgga gccccagact ggacccagcc cttagctatg 90180 atcaaaggac agctcgggat atgattaaag ggctagagaa agatgattta ggctgagaaa 90240 gaggaggcca aggagcaact ggattgtcct tgaatgtgga aaaggtaatt atgacttgaa 90300 gggtggtgcc cagctgtttc ccatctcctc tgaggacagg aaaaaaaagg aaataaatga 90360 tgtacaatta gagcagttgg ttagatacga gggtgaactt cctggctggg agtatggcca 90420 agccctgatt tgggtttcct gaaagagctc ggggaacctc cttacctgga ggtttctagg 90480 cctggtcatg tggctctgag tgattacatt gaaggggcag tggctggggc tggagccggt 90540 gggctctgag cacagtcacg aaggcatgcg cactttctgg ctgctctcct gccattgtcc 90600 cttgggttcc cattttggtg aggcgtgcac cctggcggcg ctccccaggg aactaaatat 90660 gtttgctgca ctgtgcgtgg agatggagaa tgtacaattg gctgaccctg tgctaatctg 90720 gtggaactcc atgccagccc tgggaaagaa caattgcatg ggtgtgtcca cactcaccag 90780 gtgcttttta gaaaaacact cgagaataat gctgtggctt aggatggctg ttgtgccgga 90840 cccggcatct tcccaggggg gctgtgttgt tgggctgagt ttcttaggta ctggaccccc 90900 aaatccccaa atacggcgtg gacaggtggc ccagtagggg ctggactatc cgataggccc 90960 aggtgctgga gttcagacaa gacataccct ggcctggcgt ggaagatacg gggtgctatt 91020 aatggcagca atggctgcat ttctgaaacc cgggctccca ggccgacgag ggtgtgcacg 91080 catctgaaat gtctgtggtt ttgcagttcc catgtccaca aactcacttg gttgaaaata 91140 gttcaaaata tccaaagcat gagggaggga gtgcctgctt ttcttaaaaa ggaaggactt 91200 gatttcatct acttaaaaag ccacccaaac ctagaacatt ttccgcaaga gaccccctgc 91260 cccccgcctc tccagaatgg ctggagagtc tcagcactcc tgcacatttg ggatatttca 91320 gagggggtgg ggaggggcaa gtgggcagcg agcgacctca gacccaggat gagctgtcag 91380 gcgctccccg gccacacatt caagggaccg gagtgcagtt gtagcgttgc ggcctgctgc 91440 ttcgggggtg ggggtgttgt tccatgctgt gaattctcac atggcccctg actctgggca 91500 gaggccgagg gtctaaggga cggggtgaca gggagagcat gcaggagtgg gtttctggct 91560 ttccagggcg agtggaagaa gcgcctctct ctcttgtagg tgacagacct ggggggccct 91620 tcttgaggat gagagcctgt tgcttctcaa gttctgtgtc taacccaggt ccccaggtct 91680 accccagccc ctcggccctg cctgccttgt ggatgatata gtttaagggt agagaccgct 91740 ggcctggagg gaaggctagg cctcaggtta gggcccagaa gggagggaga agcccttggg 91800 gcagctccct ttctgctcac tcactgccta gctccttcct tcacaccttc cttcggaaac 91860 gtctgctcct gacaaggtct acttcctgct ctcaggaggc ccttattgtg gaggaaggga 91920 ggcgtcgccc gtccctggct tctctgacag ccgtgttcca tccccgccct gtgccccttc 91980 tcccggacag tgccttctcc agggctcacc caggagggtg cagcggtggc ccccggggcg 92040 gtggtcgtgg tgggggtgtt agctgcaggg gtgccctcgg tgggtgggag ttggtggcct 92100 ctcgctggtg ccatgggact cgcatgttcg ccctgcgccc ctcggctctt gagcccacag 92160 gccgggatcc tgcctgccag ccgcgtgcgc tgccgtttaa cccttgcagg cgcagagcgc 92220 gcggcggcgg tgacagagaa ctttgtttgg ctgcccaaat acagcctcct gcagaaggac 92280 cctgcgcccg gggaagggga ggaatctctt cccctctggg cgcccgccct cctcgccatg 92340 gcccggcctc cacatccgcc cacatctggc cgcagcgggg cgcccggggg gaggggctga 92400 ggccgcgtct ctcgccgtcc cctgggcgcg ggccaggcgg ggaggagggg ggcgctccgg 92460 tcgtgtgccc aggactgtcc cccagcggcc actcgggccc cagcccccca ggcctggcct 92520 tgacaggcgg gcggagcagc cagtgcgaga cagggaggcc ggtgcgggtg cgggaacctg 92580 atccgcccgg gaggcggggg cggggcgggg gcgcagcgcg cggggagggg ccggcgcccg 92640 ccttcctccc ccattcattc agctgagcca gggggcctag gggctcctcc ggcggctagc 92700 tctgcactgc aggagcgcgg gcgcggcgcc ccagccagcg cgcagggccc gggccccgcc 92760 gggggcgctt cctcgccgct gccctccgcg cgacccgctg cccaccagcc atcatgtcgg 92820 accccgcggt caacgcgcag ctggatggga tcatttcgga cttcgaaggt gggtgctggg 92880 ctggctgctg cggccgcgga cgtgctggag aggaccctgc gggtgggcct ggcgcgggac 92940 gggggtgcgc tgaggggaga cgggagtgcg ctgaggggag acgggacccc taatccaggc 93000 gccctcccgc tgagagcgcc gcgcgccccc ggccccgtgc ccgcgccgcc tacgtggggg 93060 accctgttag gggcacccgc gtagaccctg cgcgccctca caggaccctg tgctcgttct 93120 gcgcactgcc gcctgggttt ccttcctttt attgttgttt gtgtttgcca agcgacagcg 93180 acctcctcga gggctcgcga ggctgcctcg gaactctcca ggacgcacag tttcactctg 93240 ggaaatccat cggtcccctc cctttggctc tccccggcgg ctctcgggcc ccgcttggac 93300 ccggcaacgg gatagggagg tcgttcctca cctccgactg agtggacagc cgcgtcctgc 93360 tcgggtggac agccctcccc tcccccacgc cagtttcggg gccgccaagt tgtgcagccc 93420 gtgggccggg agcaccgaac ggacacagcc caggtcgtgg cagggtctag agtgggatgt 93480 cccatggccc ccatccaggc ctggggatat cctcatccgc ctcccagaat cgggccgtgg 93540 gggacagaag gggcctgcgt gcgggcaggg agagtatttt ggctctctcc tgtcttcggg 93600 gtttacaaag tgtgttggga cttgcggggc tgctctgtcc aagcctgggt ctggcgtccg 93660 cgtctctgag cctgtgagtg cgtgcgcttt cctgcgtcct cttgactgcc ggtgctgggg 93720 ctctgcgtcc tgcgtccgcg ggagtaaata cagcaggcga aggggaagct cacacaatgg 93780 tctccagcgc tctggggcag ggcttctgag gggcgggcct gcctctgccg ggacctggag 93840 cccccgcccc tcggagaggc tcctaggctg acttgggcag agccctctgg tgggccggga 93900 gggggaaagg ctgtgttgaa atgagcaaac tgtccaggtg tcaggccaag ctgggaggtg 93960 accagcctga ggtcctcccc gctccatggc cagaaccagg gctgacatct gggtgtcctg 94020 agcccagctg cccacacggc ccacctgggg tcagccctat ctgagtgggg gaggcggggc 94080 ctcctggggg accagaactt tggctggacg ccaagcagag tgccagtggc tgttcttcag 94140 ggctgggcct gaggagggtg tggggcggcg aagggacggg agggggttgt gatccagtgg 94200 ccactggcgc tgtgcagagt gtgagctgga aacatcgtag ttactttgtc agcttagtgg 94260 tgaaagccct ttttcaggct ctatcccttt gcatccctgc ttcccagagg gaggggaggt 94320 ctgggtctgc agagctggga gggcttgctg ttcccgcccc cctcccccac aacacctcct 94380 catctggaca tctttgggca catgctcata ctggggtctc cctaggtcca ctgtgttccg 94440 ttgagcctcc tgcagtcccc gagtgaatgt gacctccctg cccctgcctc tttgcaactc 94500 ctccctgcga ccgctcctcc aggggccttc cttgtcccaa atgtccaagt ggcacgactt 94560 agccggtctg accactttcc agtaagccct tatggagaga ggccctgtgt tgtgcagagc 94620 tctcctcctg cctgcgggat cgaggtctct gctctcagtt cctaacagaa agtgtcgggc 94680 ccccagtggg atttctgggg aagaactctc gtgtctcaac gggagccctg tggcgggagg 94740 ggaggccagg gtttggggtt gtgttcgttg tacagctgtc accatttgca ctatgaaagt 94800 tgttagtgcc ccttccttgg gtctctgggt gtaactccac ccttgccccc atgtgcctcc 94860 atctggagct gcttctgcgg ctgtctccca agccagtttt gtgaccctgt aatttagtcc 94920 aagacaatgg gctcattgag accatcctgg tgcagcagtt ggcaatcctt tggctctggg 94980 ggaaggtttc tcagtctcgg ggagtggggc ctcaatctgc tggttccctg tgtttatcag 95040 tctccccctt gtgtgtcctg aatggttttg ctgggaattc tggtcttaga gccatcaggt 95100 ggcccgagtc gataggcgtg agagagtgtg tgtgtgcatg agtgcgcatg tgcatggggg 95160 ctgacctggg gtatggaaag gtggccctcc ctggtgccca aggagcctgg agtatagttg 95220 gagggtgtgg gggtgtgtat atgggagttg gacaaccttg ggtggacaga cagacgtggg 95280 gaagggatga ttgaaggagg tggaggagag agtgtgattc agcccagcca ggggtgatgt 95340 ggacaggcag cttccgaatc agggtagaga aaagtcacca ctagctagca ggggagaagt 95400 cagtatggag gaggcggacc ttgagggaga gtaggaattg gattgcaaga ggaaggagag 95460 ccttctggcc agcagcagcc agcagcagtg ggggaggctg gaatgagctg gctggagagg 95520 gggctggggc ataaggaggg gcctgcctgt gaagatcata tgggccaggc tgcggagggc 95580 caggcatgcc cgccgggagt gcagctggtc cacgggaagc atctggagtg gctgggaatg 95640 ggcgcaggag cagcgccgtg ggagcacagg tctctttccc ggggcggctc acctggtgtc 95700 ttggttcctg caaggtaggc cgaaagggtg gggaggaaac tgccagctcc ttacagcgct 95760 gggatggtgg ccccagggtt cctgaggcca gcggatgtgg gtgcctgtca ccatgtgggt 95820 tgctgagggg cggagactcc aggggccacc ccaaagcagg acgagctctg agccacggca 95880 tctctggggg cagttttcca atcgagcaga cgtctaggcc tggaatcctg taacagaggc 95940 cacagggccc tgatcagggt gttctgggag gcttagaact agtggcagta tacagggtag 96000 acggcaagtg acctggcatg gggaaagagg caggtgccca ggccggcaca gcacacccgt 96060 aaggaacagg tagacgggaa gccgtccgtg ggcctgtgtg tgtgctcgga gttaaaattc 96120 tgccaatgtc ccatgtcctg ggcacatcta ccccctccct ggggagcacc tttctcttca 96180 ccttttcctt ccccgcctgt ccccttcacc cagggccttc cccatccctc ccgtcttggg 96240 gaccgagggc accatggctt tatgttccat caccgatgag ttgcacaggg attcagtcct 96300 tccgctgttc aggccgggtc cttcaggctc agggttccca ggaatggaga gggtatcagt 96360 gtcttccatg gactcaaact tcccgcatcc cgcctttgct cccccttcaa gataggtctc 96420 cgagcttcaa ggttttaggg ctctgtggag gccgccacgt agcagcaagg agaatgtttt 96480 gtatttggct gatgagattt ttagagtctc attttctact tttccactgt acaaacgggc 96540 ctccaggcga ctgcagcacc cgccactgcc cgtaataggg tgacaagagg gatgaccctt 96600 tcctctttct cccttctggt tggtggaggc acggggctgg cggacggcat gtgctttcgt 96660 gaattcaggc caaatctgtt atcgcaaaca cgattacaac tcgggtcttt gtgtaacaaa 96720 agcctttcca agtaccagct gttggcctgc tttgctcagc ggtgtttgct gtaaccagat 96780 ttgcacaccg agaaagaatc caaaagtcct tgatgtttgt tgaaacaatc tggcccagga 96840 cccacgtgct cagatcccag agctgtgtgg catctgagct tctcccgagc ccccactgtc 96900 gcccgaggag gacccccaga tctgtgttct ggaggcagag caggctgtgg gacgggcttc 96960 tgggtgggaa ggaccatgtg gatatgcctt cttgtctgag agtcccaaca cctccgggac 97020 gtgggagctg gcgcgctggc aggattcagg tgcctctttc ctctctagag aaaaaggccc 97080 cgttgcttgg taataggtgc agacctgtcc ctaattaatg ccagtaggcc tcttgcgtga 97140 tgaaccctgc ctttcagcca agactcaagg catcctgtga atactgcctc tctgcagttt 97200 gagcttttgt ggtgggaggc aggagccatg gggagtgggg gcaggcctct tacacgggtc 97260 ccacagccac tggcagcact gacttgatgc tctttgagtt cagagcccag ggccagacag 97320 acccactgtc ccgactacga gttggttcat ttagaggggg gcggacacag cacccaggca 97380 gcagatgcac tgtgatcagc cttgcagcgg ggctgtgggt tctctgggct ggatgtccgg 97440 gaagaggcag gtggaggtaa acgccaggac acccctgcag tgactgggtg actgcaggct 97500 ggaaatgctt tctgtgggct gtggctgtcc aggaaggttt tgaatggggc tagtggacag 97560 agtttgcatc cagaggggca gtgctttgga ggagtgaggg gtatggcagt gtagggatgc 97620 ccaggccgcc ctcactctgc cattggaaag ctgggcggct tcggtttctt cagtttcttc 97680 gcctgtttcc ctgcctgcaa agtggggtta gaaacagctc tctttgaggg ttgctggggg 97740 actctgagat gcagcccatg gcgctgagca cgggtcctgc ctcctacggg tgtggtgggt 97800 gtcgcggctg gtgtggcatc tgggcgggaa aagggggcat ttgcaaagga caggtaggtt 97860 tggatgctta aatatgcaga tctggggatg ggaggtctca ggcaagggcc tgtgtgatgc 97920 cactgtatga atgaggccgg acagcatggt caccactaat tatggaaagc acggcagaca 97980 ctagtgccag tagcgcccgc ctgggggtcc ctctgagccc gacaggtact caggctccca 98040 gtgcagccat gggacccccc ttttcctgcc tggctgacat tctggaggct ggcgtcatgt 98100 tggctgcagg ttcctcttac tgggaggttg tcctggtctt ccctgccacc atctaccccc 98160 acccccaccc tggagtgtca cagatgggtg gaccatatgc ccatctgcag ggccaagcgc 98220 tgacaatgag gtgagcactt gctggatgac cggaccatga ggacagcggg ggcgctggca 98280 gcctgcgttc ggctctgcag gctggccttt ccctgaaaag cggttgtggc agagtgtgca 98340 tcccagggag tggtgcctgc tgccctgaac attctcatcc agcaggcctc tgcaagggcc 98400 cagtcaagtg tggtgcagag ctgggctggc agctggaaca gtctcatctt gtctagtggt 98460 gagaccaagg gctgatgggc caaggctgcg tgctgcttgc ccagcccgtg gacccatcca 98520 ctgagcaccc ccatacccct acactgggcc cggggtgtca ggaggtggag gggggactgg 98580 gtgcctggaa aaacaagccc accgagagcc tgagccccca ggggtcagta tcaggcagtc 98640 accacggtgc ccggtacaca gtggccacct ggtctcgtcg gctgtcttgg tggtggagag 98700 cgtgcatggt ggccgtacgt gatgggcatc acccagggta atacagatat gcagactgtg 98760 catttgtctg taggagccag ggacttctca gcctggcaac ctgtgacctc tgcctacccg 98820 ttgggagaga ggtgctgttc cctgatagcc tggtgccggg agagcagaac tagggtctcc 98880 tcctcctttc tccacctccc atttcttaca tgcccaggca tcaggggagg tcacactcag 98940 ggatgagtct tggccactgg gttcagggcc tcactgttgc catctcttcc ctttgccagc 99000 cagccaaatg cccgtccatc atcgtgccgg ggatggggct ggcctgctcc tctgaagtct 99060 ccttggtgta tagcctaggc tggagccccg gacgattccg ccaccccctc ccccgacttt 99120 ttctttttat tttgattcat cccagaaacc cagccaaaaa ccaagttcct gtgctctccc 99180 ttgacaaagc cactgaggaa aaatggtcaa acactgcctt tctttccaaa gccctcttgg 99240 tttttcccaa atttggaggc tctgagttgc ttatgagacc aaagggtccg gaactctctg 99300 gaacacagtc ccagaagtgg gaggatttgt catctctcca gccaaacaga cccaccagtt 99360 ggcccctaga cacccccagg cgcctggggc atttctgggc tcaggctgtt taatttggtc 99420 tgcagagccc cgaggctccg tttagactgg gccagcagac agttctagag acttcaagtt 99480 tgttgtcgtt tttaaaagtc ctgccaatgc ccagaaactt agagggacaa gaagatgacc 99540 tcgatgtcag ccgggaccat aaacagtgag gcccgccccc ccccccaccc atgcctgcct 99600 ccactgctcc cgtagctggg tctccagggg attgcccgtg gccatggggg aggccgggaa 99660 tgcggggctc agactctact gggcttctcg tatttttttg tttttccttg tccatcttct 99720 ttctcggaaa tttctgaata tccccctaca gcctttggca ttctgtcact cctggcatct 99780 ctgggccaac tgggaaagcc atcatttgtc caatatccag aaaatcaagg ggcctggcct 99840 taaatacatt gcagtgccct cctccccaca tggcatcgaa tttcctgtgt cctcaaagcc 99900 aggagcctgt gccttggatg tgggcgatgg agccttgcag acacctggag cggctttcct 99960 gggagagtct ccctcgcctt cccatccacc cgcttcccct cccctgcccc aagctctggt 100020 cacagcctcg gaggggtcat ctgagtgtag gttgcctcca ggtgtacagt tggagggggg 100080 cagttacccc acatccccct gtctgctagg ggcaccccca gggactcagg tcttgaggga 100140 cagcggaagg gtggggtggg gagtaggccg ttgtctcgtg ccacctgggt gttatgtaga 100200 ctctgaatgg gcagttcctg ggagctggtt tttccttctc accccttcta cagtgctgcc 100260 cctctgaggg gctggagctc tctggagccc tttgcagcct gtggcaggtc tttctgattc 100320 tgtgcctggt ttcgcagcct ccaacccata gccagtggca tgaagaacat tcctggctgt 100380 ctctacctgt ggcctttgca ggcagcagtt ccctggggca gggcctgggg gtcctggcac 100440 ctccttgtgg gaccccttgg gtatgaggga gggagccacc tgggccacag atagaccccc 100500 ttcctgtatc caggaggttc aggatggacc tgtctcatct ttctttctgg tgggaagaga 100560 gcattcctgg ccatggggaa tgtggcctgg acagagccac ctagcctctc ccctccccca 100620 ggcagggccc tgaaagatgg agatggctct gctcctgcca ggtcaacagc cagcagtctg 100680 gtggatttcc atgcagtcca ggcaggatct ccttctgtcc ccacccccca ccccatgtgc 100740 aggaagctgg ttccaagcag ggacccttgg ccccgctttc cacgtgggtg ggcagtttcc 100800 ctgcgagggg caggccaggc ccctgcccta tgtcccccag agaccgatgt tatctacagt 100860 aagagcatac aagtcttttt ggctccaaac caggcctgga ggggtggtct tctcctctgt 100920 cctctgcctc ttgcccccca ttaaaggtca gggaatggag tgctctgtat gtttgctggg 100980 gttgggtttt ttcctttggt ttaaaatgaa gggctggaat ccctggtgca gactgcacgg 101040 tgagaggtgc tccttgggat ccactcgagg agcattactg ctgaatgccc tgccaggcca 101100 ggagcatcgc tgggggtggg agaggcagtt ggcttatttg tttatccaac agccatccat 101160 gggtacccca agggccagct ctgttctagg cactgggggt ctaggcatgg gctcaggaga 101220 aggggtagaa cgggagggct tcctggagga aggcttccta accagagacc ggggtaggag 101280 tttgccaggc aggtgatgct ggccagcttc tcttgccatt ttccttttct ttttttcttt 101340 ttctttcttt cttttttttt gagacagagt ttcgctcttg ttgcccaggc tgcagtgcag 101400 tggcgtgatc tcggctcact gcatcctccg cctcctgggt tcaagcgatt ctcctgcctc 101460 agcctcctga gtagctgaga ctccaggcac gcaccaccac gcccagctaa ttttttgtat 101520 ttttagtaga gacaaggttt catcctgttg gccaggctgg tctcaaactc cttacctcag 101580 gtgatccgcc caccttggct tcccaaagtg ctgggattac aggtgtgagc cactgcgctc 101640 ggccttctct tgccatttct gcagactcat agtgtgtgtg gaagactgta tgtctgtgcc 101700 tggcacagct gccctcggca ctcaggtggg aggtggggga gagggctgtt ggtgccagca 101760 caggtcatgg catgagacag gctcccgcag ccaagcgggg tgcaccgcag cattggaggg 101820 gccctgctgc gcacgagatc caggctctgc atctgtcctc ctccccagga ggcctggagg 101880 gctgggaggg accagggtgg tgaaataacc caggtgggag agaggcactg ttggagaggc 101940 agagggagct gcaggtttgt agcagcgagc tttaaaccct gggcctccac cagaaaacct 102000 cagaaagggc tgctttgctt ttttttctaa actacaaaag aaacccttgg ccgcctgggc 102060 cccttggggt cgggtggggg aggagatcct tcattcgcac ctttgcaggc ccagtactgt 102120 gcagagggag gagggtggag gcaaaggcga gggaggaggg tggaagcaaa ggcggggtcc 102180 ctccctagcc ccgctgccct gcctggttgc tgctctcaga cccctactcc tggcccggaa 102240 acatggaatc ttgggacagc tggggtaggg ggcacagaac ggagaccctg gtgagggagg 102300 aactctttct ccagccctgg ctgtggccac agcaaggcca ggctgggagg acctcactca 102360 aatatttaca tctctcctaa tatttaaatg atgaagcagg ctcctgcaca cagctgccct 102420 ggagccagct gttgcctgcc ctaccctccc tctctccctc cctctttctt tccctccctc 102480 tttctctccc tccctccttc tctccctccc tccctcttgc attctttgtc tctgacccaa 102540 gtccaggccc ttccagctgt tctctcctta cccacaggca cctcctgtga ctgagcttct 102600 ccttgttatt tttcataacc atttccttta attgagcacc tcctaggtgc caggccctgg 102660 gctggtactt tgtatacaag gtgtctttta atccccacga gagcccaaca aggtagattg 102720 ggctgctgag gctccagcgc tggaaggccg gcccgggtcc tcccagtccg cacctgcatc 102780 catccatcac tcccccactg tggagacctg ttccctggcc cctggctgag cacgatggaa 102840 atctctgtct actagtcctt ggagagtggg gatggctgag ggtcccgacc ctggggtctg 102900 acgggggctg cctctgcccc acttcagcct ggctgctctt ccactcaatg actgagtttg 102960 caaaaccaga ataacagtgc tacctggctg gtactttggg tggctgggag gcgtgggaga 103020 gggtgcacgg aggggctgag cgaggtgtca gcatcgtggg gatctccgag ggtagccttc 103080 ccaggcccag ggcggagtgt aggcagaggg cgcgatggcc cagcgtgccg gctcacatct 103140 ggccttgccc ttgcccacac ggcaatgtgg gggagtcatc agcctctcag tgcctcagtt 103200 tcccatctgt gcaatgggga caagagtaaa tcactgtctt caggtatggt aagcactcat 103260 acacattgac tattgcagaa tgaacacagt gagcccttct taggcttcta ctacatgcca 103320 ggcagggtgc caggccctag tggagagggg acaatgatgg gcaagctggc tcctgccctc 103380 aagggctgtc gagcagggag gaaggcggcg gctgccctga ctgtgacccg gagtggggtg 103440 attcgcaaag aggctggcgg gaggctggct gggggctggc tgggggctgc tccctctcct 103500 gcctgtgttc cgtggcaggg tattaaactg gcttttttca tggatttccg aggccctgac 103560 tgtgggacct cgggcaggtt ttgggacctt gtgactttgt tcccgcttgt cattcaggcc 103620 tttgtcctca gcagtgccca gcacacggcg acttctgcat gtccttcagt gtgtgactga 103680 ccctggagct gagacttggc agctgaggct ggacattgtc cttggataac tcccggggag 103740 gtgggggcag ggtggggctg tgagctggca actccgagtc cctagcagcc tccgaatgga 103800 ggctttcctc ttgtaggatt ctcggggagg aaggagggga tgggggagat gaggcttgtg 103860 agtcttcagg agggcagagg ttcacacctg cagcgcccca gaaacactcc ggggtgccca 103920 ggcttaccca gccctcctga gccagaacca ccaagagttg gggaccagca gtccattttt 103980 tagcaagatc cagaaatgat tctcctgaac agtccgagcc aagaatgaca tatctggaat 104040 cagaacatca gaactacaga ggaatcgaga gaacgggccc aaaatgtgta gggacctcag 104100 ccacatggcg ccacatggag gaaagcaccc aacatcatca ctgtatgaac ctgtttaaac 104160 acacacacac acacacacac acacacacac acacacacac acactcccca gtaaagagtg 104220 gaaagacatt tgtcagaata ttgatggaag ttacctgggt tgtgggttta tagatttttt 104280 ccctttgttt ttgtgcattt tgcaaatttt cggctttgtg cctaaattcc ttttacagtc 104340 aggaacaaag caatagatgt tattttttaa agttcatggg ctcgtgcccg taatcccaac 104400 actctgggag gctgaggcag gaggattcct taagcccagg agtttgagac cagcctgggc 104460 aacataggga gacccccacc tttttttttt tttttttttg acagagtttc actgtgtccc 104520 aggctgaagt ggcggtggca cgttcttggt tcactgcaac ctctgcctcc caggttcagg 104580 tgattctcat gcctcagcct cctgagtagc tggattacag acactcatat ttgtaggatt 104640 tgagaatcct acaagaggaa agcctccatt cggaggctgc tggggacttg gagttgccag 104700 ctcacatatt ttttagtaga gacagggttt caccatgttg accaggctgg tctcaaactc 104760 ctgtcctcaa gtgatccatc catctcggcc tcccaaggtt ccaggattac aggcgtgagc 104820 cactgcgccc ggccatggga gaccccctct taaaacaaga ataaaaataa aaataaataa 104880 aagtttactg tcaaaaagaa aaacacatca cccaacctaa tctcccccta ggattgagag 104940 atgaggaagc agaggccgga aagtgtcaca ttccctggtc gctggcagtc aggggacctg 105000 aggcctgggc tggttttctc gtgctccagg cctggggtgt caggtggagc ccctgctttg 105060 cccaaaggtc taggtgcctc tgccagcact gcttgcttct gcatttttgg ccacaaggaa 105120 tgtgggccaa aggcagggtc cttgacctct gcccaggagg gtgaagtggg ctggtcctcc 105180 ttgtccctgc tccaaggccc ctgcggctgt gcctttggaa actgctggcc cgagctagtg 105240 tgcggagctg ggacagacct caccgtggcc ctcgtggggt cattccatgt ccgggctgga 105300 agggatcttt cggtccagcc cttcctgttc ctcatcagga aactgagacc agagaggtca 105360 tctgcctggc ccggggtggg gtgtagatgg cgcttgtgac tcctgcatgc cacgtgcaga 105420 cagtccctca gctgtgggct tcccacgcaa gcagccatgc tggggataac ttggctgaaa 105480 cctgcgattt aatgaagaga agaatgactc ctcctgcagc cctgtgcccc acaggctccc 105540 tcctgccccc acccctcctg cagaggggcc tcatgctggt gggtgggtcc ctgttgctgc 105600 aatgggccca ggcagtttct gggcagtgga ggcttggctg tcttcctgcc caatgtcccc 105660 tgtagcccac gctgtccggg aagggcgggg aagcactcag ccactgggga cttcacaaga 105720 tgggtatctg ggagatgctg attggcaggc caggctcccg tggcccacag gcaggtcaga 105780 ggtcacagtg ctgagctggg ctgagttggc agctcagggc agtgggggtg ggggtacctt 105840 gctcagccat gggcctctct ggcacaaggg tttggagttt actgtaaaca actccttcag 105900 tttttccttc tctcataggc caccagcaga attgaggggc cctctgttga tgaggtgtgg 105960 cctgggaggg gctagttgtc tgtccacctg atccttgcgg acaggtgacc acaggcttcc 106020 tgccccaggg ggctggggga aagatcgggg aggcctctct ggcttcccca cttggaagga 106080 aaatacgggc ataggggaga cactttacag ggacacattt cagccagtac cctctggctg 106140 tgctgggggc acagtgcctg ccctgcccac aagaggggtc agttctctcc aggatttaac 106200 ttcagccttc agtgcagggc agatgagcac tcagaggccc agaggactca tatcacgaga 106260 gagaagctgt gaccacacag gcactgaagg ttaagcagaa gagtgggaca cacgggtgac 106320 ctgaaagtcc cagggtcagt gtggttagcc ccagatagct ggggagcttt gggtaccagg 106380 cttagcaggg gaggagggcc cccgtgacag tttgctgggg ctgctgcaac aaagccccac 106440 gaactttggg ggctgaagat ggttctagag gccagaagtc caaaatcaag gtgtcgacca 106500 ggctgatcct ttggggcctc tgcgggaggc tccggcccag gcctctctcc cagcttctgg 106560 tggctcccgg gtgctcctgg gcatgtagat gcgtcacgcc actccctgct ccgtcttcac 106620 atggcctttt ctctgtgtct ctgtgtctcg taaggatgct tgtcattgca tttagagccc 106680 accctaaatc caggatactc tcctcttgag atcctttatt gcatctgcaa agaccctatt 106740 ccaactcctg tcacattcac aggtccgagg gctagggctc tggcatgtct tttgggggtc 106800 actattcagt ccactgcggc agctgatctt aggggaagca gaatgttcta agcttggggt 106860 gagcggaggg aacgctgctg ggtggggagt gggagaccag gctcggagac accgcggatc 106920 tcctctgtct gatgagggcg tgatgaggtt ctcatctcag gtcctctgaa tggcggctgc 106980 ttctgaggag accctttccc ctggatctgc ccctccagaa acctccactt aggtccaggt 107040 cccaaggtgg atggtaagag gcggctgtcc ctgccacact tgatgggtga gtgtgtgaac 107100 ggggctggga gcaggacact tgtcacttct gtggacagat tccagaggct catgaatctg 107160 ctgctgggga aggtgcctga tctagcctga ccctccaccc ccacctcccc cttcccgccc 107220 cccttcacca gccctgttcc cagagcttca cttccccaaa ggcaggcgcc gtttcctgga 107280 cttctcagca gctaccccct accccagacc cctctcttgt aggcccctct ggtctcagcg 107340 cctactcctc cctgggcttc tgcccctcta ccgtgaggct tctgggcaga agtgtggggc 107400 cccctcgctg tgtctggctc tcgcggtata ccaggggtcc tcccaggggc ccgccctgcc 107460 cgctaggttt ccagggagct tttcaagttc ttagatgggc ttgatggagt ttcccaatgc 107520 gttgtctcag agcaggaggg gccccggctg agtccgagag tcccctcagt cacaccctgg 107580 gctgtttggg gcagccaggc agcccgtctt ctggaggtgc tgcctctctc tggttacccc 107640 ttctggaatc ttctgcgtcc agttgcggcc cctcctacac agcacaccca ccaccccctt 107700 ttacctgtga ctcttctttg tcaacctctt catgtctttg agaatggaga ccaggtcctc 107760 ctcaccctgg agttcagcag aacctaaacc aggcagatcc gtgtaggttc acgtgggggc 107820 tctgtggcca ctgtggctct gccgtcacct ccagcccagc ttggcgcgct ttggatcatg 107880 tcattcagtg ccggtcctcc aaacctctcc cctggctctg caggtctggg aagcagctgg 107940 ctcctgggtg cagctgtgac cggagcctga actctgctcc ctggggtcac cgtcccctgt 108000 aattaggctg cagctcatat tggctcgggc agaggccatc ggctgcccgc cttggggcca 108060 caacacagag agccccgtga ttaatggagg ctccacctgg gccaagtggc ccctggtgtt 108120 aggcgctttt tttttttttt tttttttttt gcatttttta agtgcttgta acatttcccc 108180 taatggacaa tgagacgagg agggagggag gggtggcttc tctgcccagg cagatcagga 108240 atggtcaccg cctgtgtgtg cagtgacagg tctgggaaca gacaagggag agcttgtccg 108300 ggaggctgga ccctcacacc gatgctgcct gtgcctggca gctctgtccc gggcctcaga 108360 acagacactg accaacacgc tcctcagggt ctccaggtcc gggtcctggt ccccggcaga 108420 gcttcccatc catgggaaga agcaccgagc agccttgctg gctcctcgca gggagctggg 108480 atgcatttct aagagcagca tgcgtgaagc ccggggtctg ggcaaaggag tgtttgggga 108540 agagtctgct gttgttggag ggtcggaagt agaggggaag gaggggcacg cggtaggctg 108600 aggaggtggc tggcgaccct gtggtgggga cgagggggct atgagcagac caggagccag 108660 catcacgttt ctctgtctcc agaatcgagg acggagagct gccagagagg ccctggcggg 108720 gtgtctgggg ccacctaaag ggcgtgggtg gattaaagct gaggaaagcc tcattttggg 108780 ggactccgta cttaaccttt gaggccctca gagctgcagc ctgtggtttt tcgaagtcaa 108840 tcacctccca gggcctcgct cctgccttca gcgacagcca tttatcaggg agtctttgac 108900 ccaaggagac ctgaaaggtc atctggtccc tctcctaccc ccaggcaggc cacacctaga 108960 ccctcccaca cagatccgtc ccacccttct gctgccttcc accagggacg gagggtgggc 109020 ggccctccca cccaggccct ggcggcccca ccccagccag gaaattcttc ctctttatct 109080 gcctcacatc tcttcccctg cggcttccgc ccatttcccc tcaatctgct cctagtggag 109140 cagccagcag ctggtttaga acccgggggt ggggggagcg ctagaccagt gcagcacatc 109200 tgagagtgtg ccagaggtgc tcccattccc atagctgatt tagtaaagaa aagaggaagt 109260 ccagcaactt agcgccactt taaagtccgc ctggaatgac cctgtggctg ccggaaccag 109320 gggcacgcgg tagatgacgg gagcaggcac agagaggcct tcgtcccgga tcagtcgctg 109380 ttgccctctt ggaggctggg ctgcctttca agaagaggac ccaaggccct gtgagcggtg 109440 gcctcctctg gagcctttac tgtggtcctg gttctgctct gcgtaaagag agatggcttg 109500 aagcagaagc tgctacgtgg ctgtcccagg caggcgcccg tagtcccagc tactcgggag 109560 gcggaggcag gagaatggca tgaacccggg aggcggagct tgcagtgagc agagatggca 109620 ccactgcacc gcagcctggg cgacagagca agactccgtc ttaaaaaaaa aaaaaaaaaa 109680 aaggagtaga gaaatctttc ccagaaggcc tgcagtcacc tccccttcat gtttcagagg 109740 taaaaaaaaa aaaaactgca catttcgctt tttttttttt tttttgagac ggagtctcgc 109800 tctgtcgccc aggctggagt gcagtggcgc gatctcggct cgctgcaagc tccgcctccc 109860 gggttcacgc cattctcctg cctcagcctc ccgagtagct gggactacag gcgcccgcca 109920 ccacgcccgg ctaatttttt gtgtttttag tagagacggg gtttcactgt gttagccagg 109980 atggtctcga tctcctgacc tcgtgatctg cccgcctctg cctcccaaag tgctgggatt 110040 acaggcgtga gccgccgcgc ccggccacac gtttctgttc ttgaacaggt ggctccctga 110100 ccctgggtgt ggttactcca agaccttgct ctggtggggc acaattctgg ccccaggtag 110160 ggcgaccgta taacttactg tcccttgggg gacacgttag tgaaagggac ccttgaatga 110220 ctacggtggg acaacagatg tgagctgggt ttgtcccagg aaggctggat gtatgggcct 110280 cttgagccag aggagacaac agcagaaagc tctgcggctg atgggaccga gcaggagaag 110340 ggccggcgga ggctggggca acaacgcact tgcccactgt gaagggcctg tgtgagctga 110400 tggctgatga gagggcagtg gggcgaggct gcctcctgcc aggctagacc agctccagga 110460 cacccatatc tccttttcag aaccggtgac tcagtggcta gaaggggctt cagaattgac 110520 gggacactga gggagtcgaa tggaatggct ggagtggcca cagcaggctc taggcctcct 110580 cccgtttctt ttctgtgttc tgttcctggg gtctatatcc tggggttgct gtaacagagt 110640 gccacaacct gggggcttac aaacatagct tccggcggct cctggagatt cctggcgttc 110700 cttggcctgc agacgcatca ccatcatctc tgatctctgg cccctgtctc cacgtggctt 110760 tctccccctg tctgtgtgtc tttctccttt tctgtctttt ataaagatgc tcaccattgg 110820 atttagggcc cactaaattc agaatgatct caccttgaga cccttacctt aattacatct 110880 gcaaagatcc gttttccaaa tgtgatcatg ttcgcaggtt ccaggagtta ggacttaaga 110940 catatcgttt tgggggacac tgttgaaccc actacattta ataaacccag agttggtgcc 111000 aatgtcccct gcggacacca tagcagattc tggaggttcc ttgtaaagga atccgtagga 111060 cttcttttcc cttctggagg gatgagactg tagctgggct ggggaaagct gctggttcaa 111120 gctggggctg gttcagctgg tgctggcttg ccaggttgtt agagagcttt atccagggag 111180 aaattaacat cacaaagttg ggggataaga gaaggtttgg aatcccaagg gctggctgtt 111240 gaggtcagct gcccacccct ttgtgttcca tcttacaggg acccaggcct gccagtgctc 111300 cgtttctgga aggaatgctg tgggctgctg tgccccatag gcagggtgga gggtcccctt 111360 gcagccagcg agctgctctt cctgtagcgt gcagagggaa ggaggaggct tgtttatttc 111420 tcttggcctc agccgaaaat ccaaccacag gctctggcac taggcagacc tgctcattct 111480 cacatcatca ttgcagagtg agccaggcct cttgggtggg gctgtgatga gcaggaagga 111540 cctccggagt gcctgggact tcttgggccc agggttgcca gaggcagaga gaaagaagcc 111600 tcctcctaac acttgagcaa agatagtcat cagaatccat cagagtggcc tcctgtggct 111660 cttccctggg tgctgacccc cctggtgcat ttgaagtttt cagggatact attgacgctc 111720 cctgcacctc catccagggg ttagtggaaa tggttctttt cctccttgtc cagaggtact 111780 gtggatgatg accccaggtc ccagacctca gtcattgggc cacgtgtgca gataagcctg 111840 ggcagtcagt aacctttggc caccaagctg gcctcctgcg gactgggccg gcactggagg 111900 cgggtcttag ctgctagcac tgtggcccag ccaggcctgg ccttgggaag gcagaggggg 111960 aggggactgg gaaagggatt gagctggggg tggggtggta ccctggttct tccctcccag 112020 acctttggca ggtttgaact atctggctgc ggctctctaa ggagggagcg cctcctccgc 112080 cttgatgtgg actttgcctt ctgttcacgt tgtccctgtc cctaaacaaa tgtggctctc 112140 tgtggggagc ctgggggccg ccctccactg acactgctgt ttcctggctt ccctttgcag 112200 gctccgctca gcttcactgc gcctattttt aagcctttcc ttttggacgg ttttgcttcc 112260 tgagaacaca cccctcccca tcaccccaac tgtgtcctcc tccctatccg gagcctgctc 112320 cacctgcccc aggagccacc tccctcctcc accaagcagc ccaggccaat tctggagggc 112380 taatttgtgt ccctccagaa gcaggtcctg agacagggat ttcagtggga ggggacacca 112440 ggggatgcct gagtgtggga atgggccagg cagggaatcc agccaataaa gggtgcctca 112500 ccagctcatt gtgaccacag gtggctgccc agcccccata ccgggcagca tggggagact 112560 gcagaccgtg cccccagcct tgtcccacct ggggttgggt aagggagctg gggtttttat 112620 acttcagttc ttggccaagg actgcactgc tcactccttc cagccttccg agggcttggg 112680 cactaggaaa ggctctgggt ggagacacgg aaataggcca tgtgaagtca gtgggcgtga 112740 ttggtagcag taaggccagg acagccttgg tcaccagcaa ggtgaccaca catttcagca 112800 tgcacagccc ccacagacac acacccagga gatggtaatt acaccagcaa cagtcacccc 112860 tgccgcgtgc catgcctgca cccagggaat cttatttttt atttatttat ttatttttat 112920 ttgagatgga gttgcgctct tgttgcccag gatagagtgc aatggcacaa tctcggctca 112980 ccacaacctc cgcctcctgg gttcaagcta ttctgcctca gcctcccgag tagctgggat 113040 tacaggcatg caccaccacg cctgactatt tttgtatttt tagtagagat ggggtttctc 113100 cattttggtc aggctggtct cgaactcctg acctcaggtg atccacccac ctcagcctcc 113160 caaagtgtta ggattacagg catgagccac cgcgcctggc ctcaggggca ccttattacc 113220 ccatcacctc ctacagcagg tgacactgag gacactgagg ctcagagtag actgtggtta 113280 tgtcactctc ctgtttggtt ctcctgctct cagccctgaa ataaagagca cggtccctgt 113340 gcaggcccat acgtcctgtc tccagccctg gagcagtcct taagctcctt gaaggcacac 113400 caggcctttg ggcctcgtcc cccaagtcct ggataaatag gaggtgaagg agcctttgca 113460 actggacccc actctgccag cgccaaggcc ctgcctgact acccacccca ccctacacag 113520 atcagggacc tgtgccaagg tccagtgtca caggagagtg aagacaagga ggtgcccatg 113580 gcgtacatgc tgctggactc actctgtaga tcctaagggt tatggggagt tatctgccag 113640 gtgaggtttt cccgtggctt tttcctgcag gctcagggta gcatacaggg aggtgcttcc 113700 ctactccttg gcaccatctg tccggcttcc ctgagccctg accctggctc ctagatagcc 113760 agtgtttctt cagggacaga acctgctttg ctgctgctca gaggagaccc agtttgacca 113820 gggctagcgt tcctggaacc tgagcctgga attccaccct gccctgggca gaggccacgt 113880 tgctccctcc tacgagagct gagctgcgca tgagattatt ctgaccttgg gctctaccat 113940 ttctttgcat gacatttgtc ccaggctgga gcagggctct gtggctcgct tggtgttccc 114000 tccccagact gaggcctgat atgtacacca ggaagtgctt gatctggttt caggagctgg 114060 gagcggtttg ccaggcagcc tgtggtcaga gcaggggcct taacaatggt cccttgtgcg 114120 gcacattcct ctctaaatag gcccaggtcc aggctgctcc tgtttcgacc ccgccatggg 114180 cctggagggg aaagtttgca tctggagggt ggcccactgt ggcctctttt tgtgtagcag 114240 ctgagaccgt aggtgcttga gaataggaga agccctgtgc ccatcctggg ctgtgagatg 114300 tttttccaga ggtggggatg gggatgggcc agcatgcagt tacccacacc ctccagcttg 114360 ttggcatcaa ggtctgtgta tgtgtgtgtt tttttttttt taattttgtt tttccaacat 114420 ggagtcttgc catttgccca ggctggtctc ggactcctgg ctcaagcgat cctctagcct 114480 caggttccca aagtgctggg attataggtg tgagccacca tgcccagcca gtaccaaggt 114540 gtgtttttta agagcaatat tggccgggtg cagtggctca cgcctgtaat cgcagcactt 114600 tgggaggccg aggcaggcgg atcatgaggt cagcagattg agaccatcct ggctaacacg 114660 gtgaaatcgt gtctctacta aaaatacaaa aaaattagcc agacgtggtg gccgggcacc 114720 tgtagtccca gctactcggg aggctgaggc aggagaatgg cgtgaacctg ggaggtggag 114780 cttgcggtga gccgagattg cgccactgca ctccagtctg ggcgacagag cgagactgtc 114840 tcaaaaaaaa aaaaaaaaaa gaacaatatc gatggtttta ttccctgaac atgctaagtg 114900 atccccatgt agtataagca tctcagaagg caggaaaatg taatgaacaa cacccaccgc 114960 cattcattcc atccagagat cgttattttc tgcccgggtg tgagtgtgtg tgtgcgtgca 115020 aactgcacat gtgtgtatga aatggaatta ggatctttgt atacatcttg tgtcctgcta 115080 tttttactta atattctcgg catttctcat cttcaaaaat gtgattttaa tgatggtgca 115140 ggcctttgac atatgggttt agaaaatctg cggaaacccg gactgtttcc aggttttgtc 115200 agtttaatgc tgatgcaaat gtcctcgtac gtaaatcttt ctgtacttct gattatttcc 115260 ttgggataaa ttcccagaag tgggccaaag cacatgaacg gtcttcaggc ttttggagca 115320 agttgagatc ggtggggatt ggagaaggga cccagggagg cttttgggag cttgcgagat 115380 tggagtctgg ctttagggga cttgaattca cagatgaagg agatggctgg caaaggtggg 115440 aacctcctgc tctatgggtg ggggggtgac actgctttac cttccagtga cagcatgggg 115500 atcctcccaa catgacctgg ctccgcatct ttctgacact gtgcacggtc cacagttgtg 115560 atgctcagct gggagcctct tctgtgtcct tcagttgcat taactccttg cagacagagg 115620 aggaagctgt ccggtgctcc tccctgctgc gtgggtcctt tgaatctgcc cagttgggcc 115680 tgtggatctg tgcagtcacg tacggggttc taaaatctgc aaaatgacaa gctcacgaac 115740 actctcgctt ctgtgggtga atgtggatac cccttggctg cgtctccctc cacagggaag 115800 atggagacgt gtaaagtgac aaggacctgc tacccctggg caggttatgc cggttccact 115860 gtgaggatgg tggcaggggg cttcccagga ggcctgcaca ttgggaagag aggggcgacc 115920 gtgtgtgact gcaggaccca gggcgcagtc ttaggactct gatgggggag gagatgctgg 115980 ggagccctgt tctgccagcc tggtgacaga catctcctaa tgtttcccgg ctgggtacaa 116040 ctcacaatgt cctccgtggg gaggcaattg cccatgaggc atccctggca gggatgatct 116100 tgtttcattg ccacatatcc cagcaatgaa acaagaatct agagtgatgt gattcctccg 116160 atgacttctc caaccatctg gggtttttgt gcgactccaa gaagggggaa ggaggcagct 116220 ctcgctcctc tgggctcctg atgtggcagc tctggaatgg ccacgtgtcc gttggcccac 116280 agtgggccat ttgtcgaatg tggttgtggt gggattgggg ctgggctgga gagtgggtga 116340 ccacaccagc tagcctcacc ctgggccact gtgcagccag gggtttcatc ttcccagggg 116400 tctcgttgtg agtgtcctgg ggctgctgga acaaattact ggaaaccaag tggcccaaca 116460 aagattgatt cgctcatggt tctggaggcc acaagtttga catcaaggta ttggcaggac 116520 cacactccct ccgacagctc gaggggagga cccttccttg cctcctccag cttgcgttgg 116580 cccaggcgct ccttggctct ggcagcatct gcagtctctg ctctcatcac gtagccctcc 116640 ccaccgtgtc tctttgtgtc ccaagtcccc ttctgccttt ctcctataag gacaccgagc 116700 actggattta gagcccatcc caaatccagg atagtctcat cccgggatcc ctaatcacat 116760 ctgcaaagac cctttttcca aataaggtca cattcgtggg ttcttggggt taggtattag 116820 acatgtcttt ttgggggtca ctagtcaacc ctctacagaa cctcagacga aagtgaatct 116880 tcacaggctg aaatgggggt gaaggtctag tgcgtccctc ctccttggga gctccctcag 116940 ggcttgtgcc tatcctgtga tcctgtgatc cagccttttt tttgagatga agtcttgctt 117000 tgtcgcccag gctggagtac tgtggcacga tctgggctca ctgcaacctc tgcctcccga 117060 atttaagtga ttcttctgcc tcagccttcc aagtagctgg gattacaggc gcccaccccc 117120 atgcctagct aattttttgt gtttttagta gagacagggt tttaccatgt tggccaggct 117180 ggtttcgaac tcctgacctc aggtgatccg cctgccttgg gcctgccttg gcctcccaaa 117240 gtgctgggat tacaggcatg agccaccacg cctggcattt agtaggtttt ggttgttttt 117300 tttttttgag acagagtctc actctgtcat ccaggctgga gtgtagtggt gtgatcatgg 117360 ctcactgcag ccttgatctc ctggcctcaa gtgatcctct cacctcagcc tctcgagtag 117420 ctgggattac aggcatatgc caccacccct ggccaatttt tgtattgttt agtggagtcg 117480 gggctttgcc atgttgccca ggtttgtctt gaactcctgg gctcaagcga tctgtccacc 117540 ttggcttccc aaagtgttgg ggttacaggc gtgagccacc acgcctggct tagtaggttt 117600 tctagaagcg cctgaggcct ggtgaaggca tggtgtcatg gagtagagaa cattcaactc 117660 tgttcccggg gagccggaac acacccctcg tagccaatct caacagtcat gacgtggcca 117720 ggatgacatg gggagggggt ggtgtggact gtgtgggagg ccagctcccc gggaaggggg 117780 ctggagtggg cttggctttg aggaggattc ccaagaggag gaggaggcgg tggcatgctc 117840 gtttgggggg atggcgtgag ccagggtggg cacctcttca tttaggtgtc accttcttga 117900 cattccagcc gggacatggt ttccttgggg aagatggaca cccccagagt ggggcatctc 117960 ctggggaaga tggacacctc cggaatgggg cgcctcctgt tctcactgtt cttctagcac 118020 acagttgtat tctcttgcag ttctggaggc tgtgagatct cctggctgtt atctagaaca 118080 aactcgcctt tgagcagcgc cgtcctgatg gtggggtggc ccctgcgggt ggaacagccc 118140 ctgctgtctc agagcttact gagagctagt gggcatggga gtggtgctgg accgaaacac 118200 ccagagggat catagagcca ggcagtaagc acagaggcca gctagtgggg agggagggac 118260 ccatccatga aaagacacca agcattgaaa gagaggagag gatggttggg gaccggcaca 118320 catgtgcatt ttgcgcagat ggccaaggtg gtgaggcgcc agccacgcag acaactggag 118380 gaaggaggag tgccctaggg gaggggccag ctccggttct agaatgatcc gcttgtgcac 118440 gtgggcctgg ctggaataaa tcattgcatc cgcaccgtag actcaatcgt aagctcacac 118500 cagggcagcc tctgctttgg tgcagtgtct tcgatcatga gttggccatg gtgggggtga 118560 ctccaagggg actcccaagg agggggttca ccggatctcc cagggaaggt catttgtttt 118620 cttgggttgg acctgggaca aggccttctc ctgtctagtt tctgttctcc aacttgaccg 118680 cacggaagga tgctgaggac acctggaagc cggcccctgc tctacagcac ccataggaca 118740 gaggcacacc atgtggggac agtttggaca gtgctcagga ggcagggagc agatcagagg 118800 accgcgggag gccctgggaa ccgcacgagg acccaggcat tgagctctgc actttctggc 118860 atcagcccga tgtacagtct ggctctgtgt ctaccccgta cttcactttc cccatctgta 118920 cgggggcggt aataatattc tttacagccc aggtttaagc gggtgtagat gtgatgagct 118980 tggtaagccc atctcattac attcagttct gggcattgaa ccctggactt tctggctggt 119040 agaagtggac attcaacctt tccttggggc cctggggctt ctgcagaatc agaacacagc 119100 cagcagtttg catgcagggt gcagagggac agagggacac catgtcggga gcccacacct 119160 ggcacacccc tgactctggg gctcagtgtc ctgctgccct gcggccacgt gatcagctag 119220 aggtcatggc tggacccata ggcgaataca gcctgtggat ttgattttgt ttggccctgc 119280 ggtgttttat tttattttta gttttagttt gtggagacag agtctcgctc tgtcagtcag 119340 gctgagtgca gtgacacgat ctcagctctg caacctctgc ctcccgggtt caagcgattc 119400 tcctgcctca gcctcctgag tagctgggac tataggcgag tgtcaccatg cccagctaat 119460 tttttatttt tagtaaagat ggggtttcac cacatcagcc aggctgctca gtgttttaaa 119520 aagggcttgt tttgctttgt gccagcattt aaagatcagg agatatcata taaagatcca 119580 gatttctact ctcttgagaa gtgaacagct ctggccacgc cgggcccata tcctctaggg 119640 cagtgacgga gctgagacag ggcctgtgac aactgagagt tctctggagt ccacacggct 119700 ccttgcccag cttctggtgg aggttgagct tagtgaccca ggatttcgtc tgtgtccacc 119760 aagaaggaga ggtgcctgtg gcttagagag ggcgcccaca ggagtgcctt gcccaggaag 119820 ctggcagctg aggcggccag ggttaggggg ttgggcttcc tcttcccctc cccagtgcct 119880 gagtgcattt ggaggaagag agacgggtga ggggaaggca ctgaaattgg tcctggagcg 119940 ctattattgg gggctgggga ccagctgtca tcccttttcc tgtgggcagg ggaggcagtg 120000 gtgggatccc atgagacccg gactctgtgg cctggtgagg cagggagcgg ctggggagac 120060 actgtgggtc tccacagggg tgcgctgtgg gtctggcctg gggaaggagc tggtgaatgt 120120 gcctgccatg tgggtccctc cctgctctgg ccctgataac caggagcggc tggctctcat 120180 ttggagtgcg gttgtgggga ctgtggaggt ggcagcttcc caggtaccat ccccactgcc 120240 tccgagggag cagaccctgg tggagaggca ggatggctgc agggcgggag ctggtggttg 120300 gcatcactgc acgggcttgt agtagtggat gggaagatgc aggagaggct gatgactgag 120360 aaagttggtt cctgtggact aagctggggg agccggacaa ccaagtggtt agaaccttgg 120420 gctctggtat cagcctgatg tacagtctgg ctctgtgtct accccgtgcc ccactttccc 120480 catctgtact gggggtactg gtattcttta catcccaggg ttaagcggct gcagatgtga 120540 tgagctcggt aggcccggcg cctcgccggc actgaaagct ccagtgtccg cccttagtgt 120600 cattgatggg gttttgttcc tgctgcggtt ctgattggtt acagttgcgg tcacttatta 120660 ttggaggcat gtcccccgct gtggctgatg gtagaggtgt gtttgctggt ggtgtcccag 120720 tgtgtgcctt ggctggaggt gaggagggat aaaaacagcc gcgacaagaa ggaaatcaag 120780 gccgggcacg gtggcgcacg cctgtaatcc cagcactttg ggaggccgag gcgggtggat 120840 cgcttgaggt caggagtccg agaccagact gaccaacatg gtgaaacccc atctctacta 120900 aaaatacaaa aattagccag gcatggtggc ccgtgcctat aatcccagct actggggagg 120960 ctgaggtagg agaatcgctt gaacccggga ggtgccgctg cactccagcc agggcaacag 121020 agcaagactc catctcaaaa aaaaaaagaa ggaaataaaa gtcttctctg gaactagaac 121080 gttcctatgt agacgtagct ggagggggag gctgtgtggt ttgcgccgtg gccatggcaa 121140 gacacgacgg gcagcatctt cccactccag cctgcatctc tgccccagaa ctcatgatgg 121200 ttctcctagg atggggctgt cccttccgct tgctgagaca tgaaggacgg gaagagaccc 121260 ccggccctca ccgccgcatc gcctgccttc ctctgctgct ccttagcagg aaacatgccg 121320 gagtgttccc tagccatcca ttcaccaatt gcatcccctc tctttatttt tcagccttga 121380 aaagatcttt tgaggtcgag gaggtcgaga cacccaactc caccccaccc cggagggtcc 121440 agactcccct actccgagcc actgtggcca gctccaccca gaaattccag gacctgggcg 121500 tgaagaactc agaaccctcg gcccgccatg tggactccct aagccaacgc tcccccaagg 121560 cgtccctgcg gagggtggag ctctcgggcc ccaaggcggc cgagccggtg tcccggcgca 121620 ctgagctgtc cattgacatc tcgtccaagc aggtggagaa cgccggggcc atcggcccgt 121680 cccggttcgg gctcaagagg gccgaggtgt tgggccacaa gacgccagaa ccggcccctc 121740 ggaggacgga gatcaccatc gtcaaacccc aggagtcagc ccaccggagg atggagcccc 121800 ctgcctccaa ggtccccgag gtgcccactg cccctgccac cgacgcagcc cccaagaggg 121860 tggagatcca gatgcccaag cctgctgagg cgcccaccgc ccccagccca gcccagacct 121920 tggagaattc agagcctgcc cctgtgtctc agctgcagag caggctggag cccaagcccc 121980 agccccctgt ggctgaggct acaccccgga gccaggaggg tgagtcgcag agcgctaggt 122040 cttggatgct gtggtaatgg ggggcctggt tgctggcttt gccacagaat cttggaggaa 122100 gaagctggat atggggtgga gggtgctacc ctggagaccc agaaagaccg gaatgcatgg 122160 gggtgggggt ctgcaagctc aggagaggtg gctctctctg tctgatggga acatgccaag 122220 atgccccaag cgggacttga atgagagttt ggaaagattt tctgggtttc aaggagcctc 122280 ctttatgggt caccgtgggc cttgctggga cctctgtctg ctgtgtgtcc ctggagggcc 122340 tgggaggctt agagaatgag gagccacgca ggaaccaggg caggctcatg caggggtgta 122400 ggacagggtg gagttgagac ccctagaagg gctgtcacat tctggtggct cctgcttgag 122460 gaattgcagg ctgcctggat atgcccagca gaggccgagg gcttggggaa gggaggaggg 122520 acgtatgcct cctgaggctt gcattggagc ccatggtctg gtcctcctcc cccaggaggg 122580 atggttgtgg cagagggagg ggaacatgag gagcacctta gcctgcagga caaaattctc 122640 agggcactgg gaaggggtgc ctggaccagg gggctgtgtg atagctgcac acggttttat 122700 ttgggggtgc ccttctggcg agaggagaga ggccatgggg ctccagcagc gtcctgggag 122760 ggctcaagcc cacagccgtg ctgacatgga gcttacaggc aggggattgg tgccagtcct 122820 gtgggacaca gggcctgttt ggaaatgcca ggctgtggga catggttggg tcccttctca 122880 gaagcgtgcc ccctggcccc agcagggatc gtggctccat ggggctatag taaggtgcca 122940 gctgggttag aagcccctca agagccaggt ctgattctgg gcacaggatc agaactcagt 123000 aatgctcagt aagccttctt taggttggac aaacagcaca gtctgggttt ttgatttagc 123060 tgctgcttct tatttctaac cgtggtgaaa tacacaacat acaatgtgca attttagcca 123120 ctttgcagtg tacgtttcag cggcattcag tacattcacg gtgttgcgca gctgccaccg 123180 ctgtccatct ccggtaccct tttcatcctc ccaaactgag ctccgtcccc gttagaccaa 123240 gctccccatg cccctccccc agctgctggc agccaccatt ctattttctg tctttattat 123300 gaatttattt gaccactcta ggaaccttgt gtgtgtggaa aaatacaata actgcccatt 123360 ttgtgtctgg ctcatttcac tcagcatgac gtcctaaagg ttcatccgtc gtgctgtagc 123420 atggggcaga atttccttcc tttcagaggc tgaataatat tctgttgtgc gatgcacttg 123480 tgttgtgtag ctgttcctcc atcggtggac ccttgggttg cttccacatc tctctaagtc 123540 cctctttcca tcttctttga cttttctttg acttttttga gacagggtct tgctctgtcc 123600 tccaggctgg cgtgcagtgg tgtgatcact gcttactgca acctctgccc cctgggctca 123660 agtgattccc cagcctcagc ctcccaagta cctaggacca caggttgcgc gccaccatgc 123720 ctggctaatt tttaaatttt ttttgtagag acaggttctc actaggttgc ccaggctggt 123780 ctcaaactcc tgggttcaaa tgagcctcct gcctcggcct cccaaagtgt tgggattata 123840 ggcatgagcc acccaacccc tttttggttt ttctttttga atgagagttc tccagtggtc 123900 agtgggcttg ggggctggga ggatgtgggg cctggagagg gtgtgggttt ggggggagac 123960 cagtgctcct catgctttca tgggcatgtg gagtgcacat ttgtcttggc gggtctgggg 124020 cctgggactc tgcatttcct acagaggggg catcggaaca cactgagtag ccagaggcta 124080 gtgggccttg gaaggtcctt tccggccctc agtgtgcgag tcccgtgttc cctctcccat 124140 ctctctaagc ttgactctga agagccaccc tgccccagcc acccagactc agtgacagtg 124200 gttgctggtg gcatggtgtc aggccaaagg catgggcagt ttgcagagtg gcaggaggct 124260 gtttcctccc ctgccttctg ttggtgcagg acctttgttt gacgtgccgg atacaccccc 124320 atcctgggtt gatgtgttca cactcagctg agtcaaacag gatgtggctg gggaggcggt 124380 tgtcaccgag ccatctaaat ctcggtgatg gctggtgctg gatgcacagg gacgtggtcc 124440 tggctctggg ggacaggtag ggggatgtcc atggggatgt acaagaacat tctcctccag 124500 gggcagacac agtttagccc ctaaattgtg ccagagactg tgccgggagc caggcccagg 124560 gacacaacct gcgggctctg ctttctggag ctcaccgagc cgtgagcagg atggctggga 124620 cacaaggagt gtccagggag cttccccagc agtggaagta caatttcatc aggccaggaa 124680 ggggagagaa aggcaggcca cgtggaggca gcagcgttca gagctgccag gaacctggcg 124740 ctctgggggg acggtggctt tctccatgga ataggatgta cacgttggag ccggggcatg 124800 ggagaaaacc atcagcatcc cagacccggc cacccacgga cagggacctg tgcaggtggg 124860 agtccagctc acgtggagag gtccgtgggc tgggctgaca gtcctgaggg cctaagcaag 124920 tccaggtgga ggaaatgcag ggacagacga gggcagggcc ttcccaatgg aggagtgctc 124980 ttgaaatccg atgggagtgg cttctcgggg ggcccaggcc tgagccccac tagttcttcc 125040 tccgaggcac cacctgcttg cttctccgtc ctccctctct gtgtcacgac cgttctggac 125100 acggatccag ttctctccaa ctcagcttcc tgcccatctt tccttcaggc ccatcccctt 125160 ctgcccctcc atgtggggct gggctgggag ttccctgagc cccgacatgc acagctctga 125220 ccaatctctg cggcccctct gtcccccgag caccagggat ccagctggca ccatggggaa 125280 aggaatcatg gagggagttc cgtgccctct gagcagacgc ccagcccctt ggcttctgcc 125340 tgcgggaggg catctgtgct gtggtttgtc tccaccccag agctgtgggt gcagggcagg 125400 gtctcctggg gccccagctg aattgctccc agactgactt ccccaaagca cagcactgct 125460 gagatctctt cccgtgctga gccttctctg ctcactcacc ataggcccct ccacggttga 125520 ttcactctcc tgctcagctc acacctctct ccttcccagc ttctcctgct ttggtcttcc 125580 cttggtctct cacacctttc ctcacaaccc ctttgccctg acctcctgaa ccctgacctc 125640 tgcttctctt tacatcactg ccttggtgaa ctcctatgca tccctcaaaa cctggtccaa 125700 atacctcgtg tttggcttgg gatataaatg atttgtgtat aaactttctt tcctctgcta 125760 gacttttttt tttaaatgtg aaagtagttt ttcagatcat aaaaagtaat cgagtaccct 125820 ttctttaaaa tgcaggaagt acagaaatga gaaagaacct aaaattcacc tgtaagccag 125880 cgatatccat gcttgaggtt ttgctgtata gtcttcaaaa ttcctttcat gcccccacta 125940 gattctgagg gtagggctgt tgtctttgtt tttttttgtg tttttttttt gttttttgtt 126000 ttttgagatg gagtctctct ctatcaccca ggctggagtg cagtggcatg atctcagctt 126060 actgcaacct ctgcctccca ggttcaagcg attcttctgc ctcagcctcc cgagtagctg 126120 ggactatagg cgtgggctac cacgcctggc taacttttgt atttttagta gagacggggt 126180 ttcaccatat aggccaggct ggtctcgaac tcctgacctc gtgacccacc cacctcagct 126240 tccctgacct cccaaagtgc tgggatcatg ccaccgtgcc cagcctgtct tggtttttat 126300 aaagaatccc ataaggggcc aggtgcagtg gctcatgcct gtaaatccag cactttggag 126360 gccgaagcag gcagattgct tgagcccagg agtttgggac tagcctgggc aacatagaga 126420 aaccctatct ttacaaaaaa tacaaaaaat tagccaggca tgatagcatg cgcttgtagt 126480 cccagctact ggggaggttg aggtgggagg accacctaag catgggaggt tgaggctgcg 126540 gtgagctgag attgtgccac tgcactccag cctaggagac agagtgagac cctgtctcaa 126600 aaaaaaaaaa aaaaaaaaaa aaaatcccat aagataccaa gtaagtgact tggacataat 126660 aggtgtgcca tgaaattatg ctgaaggagt gagccactgg tggtgagttg ggatggcttt 126720 tttgtggttc ttgtaggcag atgtagtgac ccccatgggt cgtccctaga gaccaagcag 126780 aaactttcct ggtcaacttt acccccagga cacctggtct ctcctctgga ggttgtgctg 126840 gagggctcag tgggtgggtg ttggcttcag tgtgggggtt ctggaaggag tcagcatttc 126900 aggagggagt gtgggcacct agatggttga aggggaggga gaggaagaga ggcgctgcag 126960 agggcagagg catccctgcc tgctcctccg ccccagggcc tggtgaggtc tgagctttat 127020 gctggtgggg tggattctcg gtttccgagg ctctggccct gcccctggac ttggcaccct 127080 ccttgctgtc ctcccacaga agggcgctca tcctttgggg tcatccctgg tcctctcagg 127140 ctctgggtgg ggacggcctt gcctcctctc ctggatccct gctcttttcc tgccccccaa 127200 catgggtgcc tctgggtgga gtggggtggg gctgggctgc agcacccagt actgagcctg 127260 caagggctgg ctgctggctc agagcccccc ccaccagagt tacccccctc cggctcctca 127320 gccacaccag ccaagtttct ccagagctgc cttataaggc gggtgctcag cgctcgttca 127380 tgggtctggt tctctgcctt cttgggatgc tcactggggg caagagggag gccaggccca 127440 gtgcccagct cagttctggg catgtcccag ctctgcccca tgagtcaact ggttctgaac 127500 tatcattcca cccctcccag cctcaatttc ttgatctgtc aaagaggcat ctgcagaggt 127560 ggctgggggc tgagctctca tgtatccacc caccccaaga accaagaagg gagtccacag 127620 tggttctggg gccacttgtg aacatggatg tgaaattggg gcggggtaga catggcagca 127680 tgtctcagta gttttcctgt gacccagagg gtctggaaat ctttgtcatg tgggtggagc 127740 gttgagggag cagggggtca ggcccccccg agctgatgat ggtgggcgtg gctcttcgca 127800 tacttggtcc gcaccgggcc gtgtgttcca ggggcagaac agggaggaat ctcagcacag 127860 acagcagggc tgccagtaca gcgttgagta tagggttaat caaagcacag ggctccctgg 127920 aaccacccaa cacagagcag tgaagaggtg gctttgggga aagtggggtc agagctgagc 127980 ctgagtgggg ggtggggagg gcgggcatca gcctgcaagg gagggacacc tactgggccc 128040 cagaagttcc tggtggggat cagggactgt gaagttgggg agagggtgac cactgtgatt 128100 tagggaggaa gggccccata gacagcccag cttctggccc cgtgtttaca ggacacccca 128160 cataggctct gagcctatcc ctggactgtg gactccctga ggcagggtgt gcaggttcgt 128220 ccagtaccag gtgtaaggca gggggccttg gtaagcgtcg agggactcac tggtgtctga 128280 tgaagcagtg agtttggatc gtgtcatgcc tcgggtcctg agcctgcagg atttttctgt 128340 ggggctgtgt gcttctgctt ctggaggtgt ccagaaggca ctgacgttcc tgccgggatg 128400 ccttactcgg aaggtcccgc tgctcccacc tcctcccatt ttcctgagct gcttgcagag 128460 ggcacccagg tcccctttta ctttgggatt gggtctcttt ctctttcccc ttctaagaac 128520 aagtaccctc cttctccgaa ctgtccctgg agcctctcag acctaggtct agagtgggaa 128580 gtcccgcatg tgctggggga acaggaatca atgcgggagg attggccagg cccggtgtgt 128640 ctccttcgtg gtgggacggg gtggggccag agaacagagc ctggctccag agcccaggaa 128700 gagaacccct cccctcgccg gcctgccaag caccgtgcag tggtgagagg aaaggagggc 128760 tggtccggga atgcagcggg tgccgagcag ctgtggaata ccttaaatag agcgcagctg 128820 cggggaaggg tggggccagg aggcaggcgc tgggggcggt ttctctgctc cgccccctgc 128880 agctctgtgg ccctgaccac ccagcctggc cccaggatgg agccccggcc cccagacaca 128940 tggcactggg tgaggccgcc tctcagcact tgtcccagga agtcagagca gctgccagaa 129000 gagagaggag ctgtgtctgt acccgccgcc tcccaggccc gggacagctg ccgggattga 129060 gggtctgcac aatggcgagc ctgtccggag gggcgcgccg cggccagaca gccatgctct 129120 gtgcggtgtg gacagagggc acattcagcc ctggaggagc gcactcagac tccccgcctc 129180 ggggcccaaa gtgtgggcag cccctaacca gaccctggat tccagcagac agcctgggag 129240 gatgccatgt ggtccaccct gacacactgt ctcacctgtg acctcatttc tgagagctgc 129300 agggaggcgc ttcctcagtt ggactccact tcctctccgg ggttttctgt gggtgttata 129360 agtgactctg tctccttcag tccaaggggg gctcctgggg tatgggctgt aactgacagg 129420 ctagagtagc ccatggccag ggctgagctt ccttcccgtt ctctctgaac actgggccca 129480 ggaaggggtt aaagtggaga tgctctgatt aaagttgagg gaggcatgga gctcccctga 129540 ccctgtcccc ccatcccact gctgctactg ggtgtactct gtggagcccc aggactctta 129600 aagaacccag agtggagatt cccggtctca tccagtgcag gtgaggggga aagtgatttg 129660 tccacagtta catggctacc atcagcacac ctgggtcaag ctcgattcca ctccacggcc 129720 cctgtctgaa acctggaact ggaaatggcc ctggaaatca ctgattccat ctgccgcctt 129780 ccaaaatggc ccgcagaggt taagatatag actcctgtaa tgccttgccc actcgtgtgt 129840 ggggaaatgg cagaggagca ccggctttgc cctcacactg cctgggctgc cgcccctgcc 129900 ctgcctagtg gctttcctct ctggtccgtt ttctcattgt ggaagtgggc acaattcttc 129960 ctgtgcagcg tggttagagt ggacagtgat gattcgtgaa gcagggtgga gcgcctgggg 130020 gattcgtgtt aaacaagcac ataaacaaaa gccaacacaa cccttactta atcagcaagc 130080 aggccttgtc tgaagcccct gggcagcacc tcatgccatc cctaggttcc aggccggtgg 130140 tgtcgccccg tgtctctctc acccgcaagc tggtgtttag aagccctgct ctgtgttctg 130200 gctcccattc tccctgtgac ctttcccttt cttcatccta aaaagcaatg cacgacgggg 130260 cgtggtggcg ggcacctgta gtcccagctg cttgggaggc tgaggcagga gaatcacttg 130320 aacccaggag gcggaggttg cagtgagctg agattgtgcc agtgcagtcc agcctgggca 130380 acagaacaag actcccatct gggaaaaaaa aaaaaaagcg atgcccagtc attcttagat 130440 agaaaatgaa gatcacatga aatttggaaa gaagtttttc tctcccattc cccaactctc 130500 tcccaagggg tggccatgtt gacagctggg tgtggcattc tcctgaattt tattcctgca 130560 gagtcattca gggcttgtgt aaaaaaagtc aatgtgtaaa tatagacttt tcaagaacac 130620 aaaggaaatc agacttctgc taccagcttt tattttttcc atttaacaac actgttgcca 130680 cttgtagatg tagcacgttc ctttttcttt ttcttttttt ttttttttga cagagcgtgg 130740 cccaggctgg agtgcagtgg tgcgatctca gctcactgtg gctcactgta acctccacct 130800 ttcgccttcc gctttcaagc gattctcctg cctcagcctc ccaagtagct gaaatcacag 130860 gtgcttgcca ccacacctgg ctaatttttg tatttttagt agagacgggg tttcaccatg 130920 ttggccaggc tgctcttgaa ctcctgacct tgagatccgc ccacctcggc ctcccaaagt 130980 agcacgttcc ttttaatggt tgtgtcatca gctgtcccat ggccctgcca ggcttgtcca 131040 gcttcccact gtgattgaga ggctgcaaca gatgttctcg cacttgtaca tgtgcacaca 131100 tgactgaagg atgagctctt agtgaatttc tgtgtcaagg atgtgtgcat ttaagttttg 131160 atctgctggg cacagtggct cacacctgta atcccagcac tttgggaggc caaggcgggc 131220 tgatcacttg aggtcaggag ttcaagacca gcctggccaa catggtgaaa ccccatctct 131280 actaaaaata caaaaattag ctgggcatgg tggcttgtgc ctgtagtccc agttactcag 131340 gaggctaagg caggagactt gcttgaaccc agcaggcaga ggttgcagtg agccaagatc 131400 gtgccattgc actccagcct gggtgacaga gcgagactcc ctatcaaaaa aaaaaaaaaa 131460 aaaaaaaaat tgatccttgt tcctgaattg gcctctaaag tggttactag aattttttag 131520 gacccctccc ctcgtcgacc tgctcagctg tctgctgggc cctgtgcagt gatggtccag 131580 cagggaggtc ctatgcccct tacccctggc tgagggccaa atgctctcca attggtgttt 131640 tattttgtgc atctcggtca agcgagaggg attatctctt cgtatgttat aggccagggc 131700 cctgtgttct cttttcattt ggaaggtgta tccttttctt gttgaaattt tttaaaaaga 131760 gttctttgta agccaggcgt gatggctaac acctataatc ccagcacttt gggaggctga 131820 agtgggcgga ttgcttgagc ttaggagttc gagaccagcc taggcaacat ggcaaaaccg 131880 catctctgca aaaattagct gggtgaggtg gtgcgcctgt agtcccggct actcgggagg 131940 ctgatgtggg aggatcattt gagtctggga gtttgaggct gctgtgagct gtggtcatac 132000 cactgcactc cagcctgggt gacagagtga gatcctgtct aaaaaaaaaa aagagttatt 132060 tgtacatctt tatcacagca ggtacgagta tcttgtcccc agctgcctac ttttgatttt 132120 gtttctggga tgttcttcta cacagaacat tttaatcctg atattgtcaa gtctctgctt 132180 tcccttttag cttttggaat tcacatcctg tttagaggtc tcctgcgttc tgaaattata 132240 ggaaagaatt tcacccacgt tttcttctag tacttctgtg gtttcatttt tacatgttga 132300 aatcatgaat ccattggaat gtattttggt ttcagcagcg aggtaggggt agatggtatt 132360 gcttggatac acagcagcga gcttggtctg gagcgggtgg ggcgtgtgtg tgtgtgtgtg 132420 tgtgtgtgtg tgtgtgtgct atttttatca gttttggtgt ctgcattgtg ctggcttagc 132480 aaaaacaatt tggatgcatt tcttttaccc tctgccttct ggaacatttt aagcagcaac 132540 ataataatct ctctgttaaa acttttcaag aattcactcg tgaaaccatc tgagcctgat 132600 acttttgggg gagtctagca ctttaaaaac ttaaactttt tccatgggtc tgtgagtttg 132660 ggagtttttc tttcttctta aaattcatta ctattttttt cctagaaaag tgtcttttag 132720 cttatttaaa atccgtcagc ttattccgag ggggttgctt tagctcgctt agtgaggaca 132780 gtgtgcagcg cggtgattga catgattgat cagcagagca cgatcgatca gtcggtgtgc 132840 aaacatgact gactgtggcc agcgtcctgg gatgctccat gttgaggcac atgtgtgcag 132900 tgcagggtga tgtgtattct gagaggggat gaagccacag gacccctgca cccttaggag 132960 agagcccccc tccccaaggc tgcagtcttg agtaggtagt gacgggactg ggtctagggg 133020 gctgagtggt cccagcaggc caagggcttc aggaattatg agaagtttgg agttgcccag 133080 agagcagctt tcaaaaccag tctggactgc agcctccaga aagacatgcg attgacacca 133140 cgaaccagga cacacctata tatggggtgg gggtggggat gggatgtatt aatgaaacca 133200 aatttccgtg atggaattct tacctttacc atgcgtgtgc tacactcagt attttctttt 133260 tttttttttt tttcccctct ctcttttttt ctttttgttt gtttgttttg gagagaggga 133320 aggctttttt tcattttttt ttaaacagct ttattgagat ccaagtaagc tactatacaa 133380 tccaccaatt tatttattta tttatttttt tgagacggag tttcactctt gtcgcctagg 133440 ctggagtgca gtggcgccat ctcggctgac tgcaacctcc gcctcctggg ttcaaccaat 133500 tctcctgcct cagcctcccg agtagctgag attacagaca tgtaccacta cgcccggcta 133560 attttgtatt tttagtagag acggggtttc tccatgttga ggctggtctc gaactcctga 133620 cctcaggtga tccacccgcc tcagcctccc aaagtgctgg gattacaggc atgagtcacc 133680 gcgtggccca atccacccat ttaaagtgca taattccatg gttttcagtc tattcagaga 133740 gtagtgcaac catcgtcacc acaaccaatt ttagaaaatt gaaaatttga gaaatttaga 133800 aaattttttt cttaagaaga aaccccgtag cctttagcta tcaatcctgc cctcctcctc 133860 catatttcct tcctatctgt gtggattctt tttttttttt tttttttttt tgagataggg 133920 tctcactctg tcacccaggc tggggtgcaa tggctcaatc tctgctcact gcaacctcca 133980 cctcccaggc tcaagccatc ctcccaccat ggcctcccga gtagctgaga ctacaggcct 134040 gtgccaccat gcccggctaa tttttgtatt ttttgtagag atggggtttc accatgttgc 134100 ccaggctggt cttgaactcc tgggctcaaa tgatcctcct gccttggcct cccaaagttc 134160 tggaattaca ggcgtgagct actgcgcctg gccgattcta gacatttctt gtacagagaa 134220 ttgcacgttt ggcctttgtg tctggcttct ccacttggtg tcatgtttcc aaggtccatc 134280 cacattgtgg caggtgccag tgcgtccctg agtaatattc caccatggca tggaccattc 134340 cattgtggac agacatgttg ccttcatcag ctgagggaca ttgggttgct gccaccgctg 134400 gtgagtgtat tcttttcaaa ttaaaaaaaa aatgctggtc accacccact agatcgtttt 134460 cttggcccac agggtgggac aagccggcct gggtgagggc caggaggtgg ccaggtggag 134520 gcggctggag cggccctggg ttgcctctgg gcgcagcagg cagaggtgca atggcagagt 134580 ctgagcaggt tccctgggcg gatctccatg ccggtaatgt ttgtttattc aagaagtctc 134640 ggccaggcgt ggtgcctcac acctgtaatc ccagcacttt gggaagttga ggcaggcaga 134700 tcacctgagg tcaggagttc gagaccagcc tggccaacat ggcaaaaccc cgtctctact 134760 aaaaatataa aaattagctg ggtgtggtgg cgtgtacctg tagtcccagc tactcggtag 134820 gctgaggcag gagaatctgc ttgattccag gaggcagagc ttgaacctag gaggtggagg 134880 ttgcagtgag ccaaaattgc gccactgcac tccagcctgg gtgacagagt gagactatgt 134940 ctcaaaaaaa aaaaaaaaaa gaaaaaaaaa gaaatctcca gtgctgccct gtgcccggca 135000 ccgaagccga gggaaggcag cattagtatg agctcccagc ccaccgggct cctgtctgga 135060 gctgacgtgc gaccaaggca cacgagggaa gcatggcgag gtggacggtg cggaggcata 135120 aggagcaaaa taaggcagat gcagtggctc agtggctcct ggtggctgcg aggagcgtgg 135180 gcaggacagc cccaggaggg cacctggaga gcagggccgg ctggggcaag gtgtgtcagg 135240 cacttgtcag gagcaaaatg taaggggaca ccaaagagct caggaatcaa cacagatagt 135300 atttaatgca gtatttttca atatcgaaat gatgcatagt aatctctatg atgaacaaat 135360 gttggaattt taaattaaga caggcccagc cctgcacgtg cacagccctg tcagagtttg 135420 ttcagcgtgg aatttgattt gtttaaaatg ttgcttcaaa atattgtttg attcctggat 135480 tttttggcac tgccttaact tttgcacctg gacgaaggcc tcaccctaat cccagctgga 135540 gagggtcaag ggctggtgaa tttggctttg gacctgcaga gcttgtggta cctgagaggt 135600 ggggccagga acaggaagga gctggtgaga acggcacccg gtatgggatg gggccagatc 135660 agagcagcac tgtggctctt tccaacccgt ggttttgctg ctggatgctt ggcgttggtg 135720 ctgagccccc ggccctctga acggagtgtg atgaataacg gggccgggga gctcttgggc 135780 ccctccctga agcagcagtg aagccaggga catgccggca gcaggcaggg agagggacgt 135840 ctggtctgtg cctggagcca gctgccccat ggaggagctg ggtgaggatg cggtgggagg 135900 aagaccttcc cagtcctgca tcctccgaag cataactgag tgcttgtgtg gcttgggggt 135960 cactctggtc cgaggacagt cttgctttgc ttagccaggc tttgaagagc caccgggata 136020 cggacagcag ccctgctggg tggcaggttg tccaccctcg cccactcaac gctggaactg 136080 gatgcagagc acctggatgg ccagtcccag agtgtctctg acactcccag tcacctcatc 136140 ccttagacca ggataagatg cgggatccca acctcgagcc tcccatgggc tccattccat 136200 gtgctcccat aagccactgg gcccacctcc tggctccagg gctgtctggc catttggcat 136260 cttggtttcc tcatctgtac aatgaaaata atagtcccag ccttctcgag gagttacaag 136320 atgcctttcg tgtgaaaaac tgggatttgg taccagacta tctggatttg aattttggcc 136380 ctacccctcc taacctgtgg ctttgggcca atctggcctc cctgtcctca gtttccccat 136440 ttatagagcc atctcattga gttgctggga ggatgaacat aaggaagtgt actcatgtgc 136500 ccagagcatt gtgattttac ttattattac caaacgaggc acacaataag tgcctaatag 136560 atgctcagtg tcatttcacg gattctgtgt gccttgtgtg tctccagcag ccaagctctg 136620 gaggtgggga agctgttgac gagttgcacg aggtaattag aaagaggagg ccacaggtgc 136680 aagggtttgg gtgacacctg tggacagaga gaggccgatg gaccctggca gaggggaagg 136740 gggcccttgc acatagaaaa tgtttcctgc atccaagatc cttgtgactc tggaacagag 136800 gcagcagagg tctgcaaatt ccaaatcata aacccagaaa gcatagaaca ttcgtagaga 136860 ggaccagaaa catcatatat cttagtgtgt atagaatttt ccacatagcc aaacaaaagc 136920 acgtttctaa ctgaagctgt tggagagttc ctgaggactt tataccagac aagggccggt 136980 aagtggaagt tcaatacgca ggagccattc cttttgttca caaatgtttg ccgtcttttc 137040 tgtctatatc cgcattcatg tgagggcact cataggtcca ccgtccagcc ccatgctttg 137100 tttgctacca aaaaatttct taagaattcc tcagctgcaa atcctcctac cggagggggg 137160 gttccaggaa cccagccttg ctcggggttg gggcacctca gcacctgctg cacaggcgtt 137220 ggtcattaaa ggtcatgtgc cgtatccgtg ggccctcggg gtctggtggc acctgggcac 137280 acagtccagt ggcggcctcc tacctgccag acactgggag tggggggctc ctcattcctg 137340 ttccctggcg gtggggggag tgccccgagc tgtcacacat cagaacccac cgactcacac 137400 gttgcggcac cttacagccc cttgacagcc tctcagcctg agagaccatc aaactgagtt 137460 cctggagagg gtggctgttg aggcctggac acaggtgtgg acaggatagc cctgcctcat 137520 ctcggagtcc cgctccggtt cagcctcttg tgggtctgaa gctcaggctg ggccagtccc 137580 tgcccctcag atggccggaa aggcagccca gccccacggc ctccttgtca ggctctgaga 137640 gccgcctggc ctccagctct gctctttttt tttcttaaga tggagtttta ctctgttgcc 137700 caggctggag tgcagtggtg ccatcttggc tcactgcaat ctccacctcc tgggttcaag 137760 caattctcct gcctcagcct cctgagtagc tgggactaca ggcgcgtgtc accatggcag 137820 gctagttttt gtatttttag cagggaccgg ttttcaccat gttggccagg ctggtcttga 137880 actcctgacc tcaagtgatc tgcccacctc ggcttcccaa agtgctggga ttacaggtgt 137940 gagccgccac gcccagcctc cagctctgcc ttgattttct cttaaggccg tgaggatgtc 138000 cacgcctcct cctttcctca cggcccattg atgtctccag atgctctgca aagccaccct 138060 cccctcggga gctccccagc tggtgacggg ggaccttttg gggatcactg cccaggtagt 138120 catgtaggtc tgtgggccgt gcttccaggc tggaccgaga cccggtgcat ggggtgcttc 138180 tggtctgagc tgaggcccct ggaagccaca gccaggaggc agcaagggac ggctgtcatg 138240 tcccctctcc cctgtctccc agggtccctg cgggacagat ttccctgcct gagcctcctg 138300 gttgcccata ccctggcctc ccaaagccca gcctgaagcc ttaggcaccc tacaacctgc 138360 ttcctctagc agcctgccct gtctcttctc tgccgatgtt cctgaaactt tcctgcctct 138420 ccttacctct tggccagaga gagactggag accctgtggg aacccccgag gggagggaga 138480 aggccgctgt ttgaacggag gtggtctttc cctctgcccc tccccaggcg ggtcacactt 138540 gcaggcccag cctcctgctg tggcagcgct tggggtgtcg gctgcctcct gggcacgagt 138600 tgggagctga gggaggcgct ttcaggaccg gagtggcaac ccagctggag gaggagtaac 138660 aggcccgtgg tcagcagcag ccgccgcagg gaccccggcg ctgtacctgt gccccagctg 138720 acccctcccg cttccctagg gtgggccggg gatggtggtc tgttgcccag cccaggaaga 138780 agaggggccg taatcagcag cagccacctc aggggacccc agcgctgtac ctgcgaccca 138840 gctgacccct cccccttccc cagggctggc tgggaatggt ggtctgttgc ccagcctagg 138900 aggaagaggg gctgtggctt ccactctaga ggtctctctc ccggtccctc ccccggtgct 138960 ggtctaactg caggcctgcc ttaggccgtg ccggcacctg ctgactgacg cttagcggat 139020 gctgatagga gagggctggg atggggaagc agcaagtccc ggtcactgtg ggctcgggtt 139080 acagatggtt gaggcacctc ctggccatcc ccaggaagca aggccccacg cagcctccga 139140 ctcacccact gcccgtgtgt atttcaggag gctgcatccc ccaaggcccc caccaggtaa 139200 cttcattggg ctgggtgtcg ctgcaaaacc acccattggg tgcggtggtc ttctggtggg 139260 gggcatggct ggggaggatg cggtggagga gaagccagct ccgtggttgg ggggagggcg 139320 gactatccgt ttcctgtctg tcccctgaac tggagctcat ggtccctccc ccaggtgcct 139380 gggccatgga agaggtcaca gccctgcctt attcctgtgg cagcctaggg gagccctggc 139440 cagtcccgtg tctcctggga gggcgacagc ctggtcaggc tgcagggcag gactggaatg 139500 cagacccctg cttggccatg ctgttgcctg gctgctctgt ctggggacct tctgttcagg 139560 aagagagaag cgggccggac agcccggctc agtgattgga agctcagctc cccatgttca 139620 gtccagcagg aagtttgcct cctcggaaca cttgcgtgct tctgcatgtg tcttcttggc 139680 tggtggttct gcgaggcccc tactgggctg cgtcatgtcc tctggccacc ctggccttgg 139740 tgcctggccc ctgtgaaaca gagatacctg ggcagtcccc cacttgtgct tgcaagcctg 139800 tgtggcttca gtgatggctg attctgctcc acccagagga cctgggaatc ctcagcccaa 139860 ctgtccagag gagtctttct cagtggggag agcctgagct gtcctcctgg tggacagtcc 139920 tttagatctc aggcggactt ccctgccggc cgttcctcct gctgcccctg ctcctctgtc 139980 ccccatctgt ctcccaccct ctcccctgca gcagccagct ggcacgggga cctccccttc 140040 cctctgggat tgtgaatgag acgactttcc tggtccttct gggtctagat ctttctggca 140100 acagtcagtg aaacccttgt ctcaggtggg aggagaaggc tcagtatgtg gtcacaacaa 140160 cggtcctaac cacatcactc tcaaacgctg gctttcactt accccttgcc ctgcccaaca 140220 gttactttca tcatcccatt ttccagatta ggaaatcaag gcgcagagag cttcagccac 140280 ttgcctgagg cccccacagt taagtgtctg gatttgaacc ctggagcagc ctggctgctg 140340 agctgtcctg gagacggggt actgtgcagt ggtcggggta ggggtggagc tctgccgtcg 140400 ctgactcccg ggctacctgg agtgataaca cagcccagtg tctgggcccc tgcctgagac 140460 tttggctgga tgccaggagc ccgagacctt ccagctcttt cctgtgtaag gcgccatggg 140520 gtgaaatgaa agaaaacccc agttagaagg tgtccccctc ttccttcagt ccctcagctg 140580 ccctggattt tgaaataaga caccgcccgt ctgtggggtg agcaggaaca gattggaacc 140640 gcatttctct ccccccagtc acagctgcca ggagctcatc tttctctgtc tcctccccct 140700 gccgcctctc cccacaagac tgggctggat gctgctggga aagtcaacag gaagtctttt 140760 ggctgcggtg gaggtggggg tctgtgcttc cctggggacc gagatgaggg ctccaggttg 140820 gctccggcaa gagcagggag gctcacgtct ctgcctgctg gttttgcttc ctgtcctggg 140880 agaaggtatc cacatgtccc agaatgcacc ctctgcgtgt acagggatgg cttttgggcc 140940 attcacctga ggtttattga tctttctctt tggaactgga gtggctcctc cacggtggat 141000 tgggctgagc tctctgcctc ggccgacgtc tttccccagg cacttcctct caccgtgcca 141060 gggtgcaggt tgctagtgga tgggtcttca ccctcgggga ttggcagctg ccacgctcat 141120 ttcacagtcg agacaccctg gccgaaggtt ctgctaagct ccatggagtg tagggatttt 141180 ttttgagacg gtctctctct gtcgcccagg ctggagttca atggcccaat gtcccgctca 141240 ctgtgatctc gacctcctag gctcagcagt cctcccatct cagcctacca agtagctggg 141300 actacaggtg tgtgccacca tgcctggtta attttttaat tttaattttt ttttgtagaa 141360 atggagtctt actatatttc ccaggctgaa ctccaactcc tgggcttaaa tgatcctcct 141420 gccttggcct gccaaagtgc tgggattcca ggcatgagcc attgtgctca gctggggttt 141480 tcctttaacc cttcctggcc cttcccaggt gcaggacccg ggcctcagcc ttatgtgttc 141540 ttgaacagct ctgggctctg tcctgtacct cctgggcgcg tggtcaggcc tctcgtgaca 141600 tcagcaggag actcaggtga agaagcaggc agaacggaat gcttgctcac ccagcctcgg 141660 ggccaggcgg ggcggccagg acagtagcag tggctggtgt ggcttcctgg gaggtcagcc 141720 cattggcgtg gccagcgaat ggggagggga gcttctcccc ttgtctcccc tcatttctgg 141780 tctctgggcc tccagggcca ggtctccaga gttctaggtg gaggatggag gtcagggaag 141840 ctggggtaag agcgggctgg gggtgggtgg tcaggcggat cctggaaaac catcctctgc 141900 aggtcccgct ttccccaggg agcactcagg gctggtcccg gggagccggg ctaatggtca 141960 cctcggatgg tgcaggggtc catccccatg aaaccgggcc catccccatg aaactgggcc 142020 cacagaagct tttggttccg gttctgttct gccccctggc tcttgcttcc aaagtaggac 142080 tcaggatagc tctgaattcc ctgccgaaat gcagcttcct gggccctaac ccagccctcc 142140 agaaccagag tctctggggt gggccctctg cttgtctagc agcctccagg ggacacttgt 142200 gcctgccaga gcaagtctaa taagcactgc tgtaaacccc tcgtccccac agccttctgg 142260 ttcgtctccc ttttcctgct gggatctgca tcaggattaa atgccaacat cagggatcag 142320 gttatacttg tgaaccctga gacaatacct gcatcttttt ttttcttgag gctgtcttgc 142380 tcgctctgtc atccaggctg aagtacaatg gtgtgatatc cactcatggc aacctccacc 142440 tccagggttc aagcaattct cctgtctcag cctcctgagt agctgggact acaggctcac 142500 accaccacac ctggctaatt tttgtatttt tagtagagat ggagtttcac catgttggcc 142560 aggctggtct cgaactcctg gcctcaagcg atccgcccgc ctcagcctcc caaagtgctg 142620 ggactacagg cgtgagccac tgcgcccggc ctgataccta tatcttgacc aagctgctgt 142680 ggaaacattg agttcccctt gatagttttg tccacagagt gaatgtttag gaaccggcga 142740 ggcatctctc acccccaccc agatggcggc ctggaggcag cgtttctgac cctgtgatgg 142800 gatttgtctc tcttgtccaa gagactttag agatgtggcc cctgaatgtg ggggcccctg 142860 ttggggtggg aacgggagct ggccctggcc attgtccagt gaccccatct cagtgcctcg 142920 atcctagcac cctcgatctc agcgcctccc cttccccggc tccgcgcgga gatcacgtgg 142980 cttgcgctga gcaatcctcc actgcccccg tcgcgttcct gctgcaggga agcctttcca 143040 gggagccagc tgacacattt ggcctccatt atttgttttt gaacaggaat gaaaggagag 143100 agtgagtaag aaagtggcag gaggtggggg ttgcagagta ggggaaggtc agagagaggg 143160 gaggaaagat ctggaaagtc caggcatgtg ctctggaagc aggtgccagc gatgagctca 143220 tctggagggt ggccgcccgc cctgagccct gcctggggcc agcagggaac actctgccag 143280 ggcatgtcgc tgggagcctg tccttggctc actttctgct gctttgagcg ctgagcagat 143340 ttgtttccat tttagggaca acgcaaggag gctgtcattc cacccctcac cttattaata 143400 tttcatgaat cataagtgac cacttactgc gtcctgacgt actccaggcg ctgggctcga 143460 agctttatgc gcttcatggg atgtatctgc actatcgccg tagaaaacgg ttcctgttac 143520 tactgcagag aaggcaccga ggcacagaga ggttgaggaa ctggcctcag gccacacagc 143580 tagaagcggc tgaccctggc tgtgaacaca gggctgcttg actccaaagc ctgagctggt 143640 ttgcagcgag gctcatggtt tctgtgccac tgtttgagcc tctggtcgag ccccttggct 143700 cagtgggggg cccagtgacc taccagctgt tccattatat gttgtggaca cctccacggc 143760 ccacctgggt gggagggaag gggcttcagg aggtgggagg ggtacaggga acacagtcca 143820 gcctgcttgg gcccaatacc ttgaccttca aggtacccct tgagggtagc atgaggctaa 143880 gctcttgttc tcctccagga ctctgttcct gtgagggcct cggggtccct tgcttttttc 143940 tgggggcctt gctggtcagg atcacagaga agctctttgc tgttgatctt tctgcctctg 144000 tatcttttgg caagccattt tatgactcag ttgctttgtc tgtaaaatgg gttgaataac 144060 attgtcctgc ctcggagggt ttttgggagg atcaaatgag acctgttgca cagaagccct 144120 ttgtaagcca tgctgactgg cggtcgccgg gcccccaagt gaatgggcat ccgggcactg 144180 agtgtgtgga ctcagtactc ggaaggaggg gctggggggt acctagaact cctgggaggc 144240 ttggacccct gctctgctca gattctgagc ttctccttgg ccagtttaat tcccatcagt 144300 agggtgaggg taaccaggac ttacgcatag ttgggcgaag tcgagtgacc acatgtggaa 144360 gtctagcgtc cttcatgcaa agtgggcagg cggccaaagt gagctctgct ccagtccccc 144420 cacccccggg gctgttcctg gcgccctgcc ctcccccaga gccccactga cctgcaccat 144480 gtgacccggg cctgggaaga tgggcccagc tgtgggaggt cgtgcgggct ggggactgag 144540 agtgccggag gagggcctcc caggaaaacc cagctgcaca ggaagccggg ccagcggcct 144600 ccggaagcct ctgggctttg caagctggac tccccagatc tgtggctgtg gggccctctc 144660 ctgcctgcag ctgagagccc ttgacccgca cctgagggct tcagaggtcc gggaggggga 144720 tgtgaccgtg tccccagggt gaagcccacc cgagtgtcac tctggataca gccctcacct 144780 cttcctggcc ccctctctgg tcatggggac gctgcctggg gggggttccc ttacatggaa 144840 ggagctgcag ctgagctggc gggcctcgca cacccccaag gccgcctgac ttccagcctc 144900 caagtggggt tgcattcacc actcaggacc tggagcctca gccagagagg gaccctccac 144960 tgcctctttc tctgtctctt gggaaaggta gggtctttgt gccccctccc acccagggac 145020 ctggcatgtt gggaggctaa gaggaagctg ccccccgctc atctaccccc caaccctccc 145080 agccagcaga gttttacctg tgtgcttaga atctgtgcgt ggagccagaa gtcacaaggt 145140 tggcccagct gtgtctgacc ctggttgtgc ggtcttggac agtcccagcc ctcctggagc 145200 tgagcatcct gatctgtaga ggagaggctg ctgtgccggc cccgcagggc cctgtgcaga 145260 ggggagtgtg tgcggctgtg agttcaggcc atgccctcag actggaggat aggatcggaa 145320 cagtgggtca ggatggccag agggtcccag cctcaggagg aggcctccac acctcccagc 145380 acctccacac caggaaatgc agccaggccc ccaggcctcc catgtcagga agcagcaccc 145440 cgccccccac ctctggttgc ctgggcctga gaagttgagc actcctcccg aatccgagtg 145500 ccctctgacc cctgcttggg tagttgtccc tcctgaactg accgcctgtc ctacacagtc 145560 ccctgtggtt tgcccgacag ggtggccagc gagtcccctg cacagcacac ctcccccagg 145620 agtgctgcct gtgatgatgg tgtaaagggt gcccccccga gcccccggag gcatgcagtg 145680 gcgcaacagc gtgagcccag gagccccggt gagctcctgg atggagaatc tgttcagatc 145740 actccccagc ctaaaccttc cctgggtgtc tgctgtgctt ggggcgctga ctcatcgtgg 145800 ggcggcctgt gagaccctac gtcacctggc cactcccctc agcccctgtt cactgcaccg 145860 gtcccctggc ctggctgctc ctggaacatg agggctcatc ctcacggaag aatattcact 145920 tgttccctcc tggaaagtcc ctccctagac ctcctggccg cctcattcag gtcttgctga 145980 agcgctgcca tcttggagag gcctccctgt cacccgcagt taaaacagcc ctcccatgcc 146040 tgtgggtggc tttctatggg gcatggatga gtattggaga gtcttgccgt ttatttgttc 146100 atatgccctc tgggagggca ggggacactg acttgtgttg tgggtgcctt gcatgtcacg 146160 ggtgctcagt gaatgcctgt taagcattag gggagcacaa aggagggaag cctctgtcca 146220 actggagcag tcagggaaga cttcctggag gaagtggtat ctggtctgct tagaatgtgg 146280 cgatttgtct gtatgcagac attagattag agggcaaagg ccattatcat aacttagcag 146340 acagctacaa gcagctaagg aattgctatg acatggactg ctcgtgattg gagctaagaa 146400 ggagtcagag acagaggtcc ctgtgctctg gcgtgagtcc ttgggggagg ctgagctccc 146460 agaatgtggg gccgcctgtg cagaggccgg aggtgggaga cacacctgtg agtgccggtg 146520 agtgtggggt gagccactgg ggctggatca gaagatggga atccctaaac ccaccaacca 146580 gccttggtgc cctgggagtg acaggagacg gggcttctgg gggactaacc cagcacaagt 146640 ggacgagatg ggatgcaggg gaaaggacaa agctctctga ggctttggga agctgagtta 146700 gggtagagcc atgacagggt gagttccaga agcaacacaa gaaaaaatag ctagactggg 146760 ttttcccttc actgtgggag atgccccacc tcacttcccc cgtcctccgg gctctggcaa 146820 tgggctgggc acagtgaatg ggttccatct gcaggagtgg tcacacccct tgggcacagc 146880 tgcctcatac actgtattga gatgggatcc gaggccggga agaacagctt cttctgtagg 146940 ttgacattgt cagccttcgg ggagggaagg acggcagggg gcctggagca tctccttttg 147000 ccatccacac tctgtgcctg cctgcagggt cttgagccct gtctgttctg cctcagtcct 147060 ggtcaggaac ttgttggagc ccataggggc agtcaggctg gaacaggagg agaccaggcc 147120 ggcaggggag ccgagagggg gccctggaca gcacccaggg ctgagtcatc ctgggcctgc 147180 ccgacttgct atttggagct gttcccgctt gctcatcatg tgcaaggtcc tgatccactc 147240 gggtctgttt aaccagcgcc cctccccagg cccagttagc ctggttttcg ttcgattcat 147300 ttattgtcat cagtgccatc cttgcaccac gtaactagcc tttgcagcat gccagccacc 147360 aagctcaggg ccctctgtgc atctcctgta accctcacag caacccggga ggcacagaga 147420 ggctgagtcg ctggcccata gtcacacagc aggtatgggg cattgccagg atttagccgg 147480 atctctgact ccagggcctt tccagggcct tgggtgggac actggcaagg aagcaaggta 147540 tgaacactgg ccctgccttg gacagagctc ggggacggtg gcctggcagg cccagctgac 147600 acagtgaccc tggtgcaggt tcaaccattg gcaaagtgtt caagtacaca cagaatctca 147660 actggggaga caggcgaagc ggtcaaggga gggctgtgag tgacaggtgg acactgtacc 147720 tactggcaga tcagctgacc ttggtgcctt ctggagcctt tcaacttcct tatccagaaa 147780 aagaggaact aacagttcca cccccaaact gggtgggagt accacattcg aaattgaagc 147840 aaagctggtc gtgtcacagg ctcggcagat gttagctgtg caggcaactt agtgaccatt 147900 tgaagtaggc tgtgcggcgg catcctcatc ttgcagatgt agtccagaga ggttagggca 147960 ctaaccctgg gtcacacagc gacagctcag gctacagaga gcagtgctgg atgggagggt 148020 gttggcagct tcaggcacag gctgggaggg ctgtggggtc agcagaggga gggcacactt 148080 cccagctggt ggggttccct tgtgcctcag tactcatgtg ggcccaaagg agctggaagg 148140 agggaggtta gagccaccca tgggttcaga agctgataag caggttattg actctgaatt 148200 tgcctcatcg tatgtaaatt ggggacaaat ttggggattt aatgatataa tgtaagaagc 148260 agacatgtca cagccctggt tatacagtca gtgtataata agtggtaagc cgtcagagga 148320 ggcagccggt gagaatggga gcatctcagc agccctccgc cccctgctcc tggttgcaga 148380 tgtacctgtt cttggctatt tgtgccccag ctccgtgtcc tccggtgtgt gtgaggccaa 148440 gctcctgggg tggggacttg ggggtgtgtc tgcagctcct gaggccaaga ccaaggctga 148500 ggccgaggct gaggctgagg ccaccttggt gaggaggaaa ttgcaggtgg agaagctcgt 148560 tgaccgtgac cttgatctga ccgtaatttt gatggtgccg atgccgtcag cacgcaggcc 148620 tcctgccctc gccacgactg gctcctgcag cccacctggc tgagaggtgt gctggctctc 148680 gcaggttgca aaatggggac atcaccgtcc gcctgggcta cagcgtgctc gccgattgca 148740 tttggggagg gactgagggc tgattgtgtt gtggggatgt tggcagagaa tcagagaggg 148800 catccaaaaa ggccaacagt tcggtgggga gaggaggcgc aaggctggtt cctgttttct 148860 gggctttgat cgaaagggaa caggggacac atctggggac agtctccttc ctggaggaag 148920 aagggcttag ggtgctggtg tggagtttgc acagatgggg ataatgagct ggagggtgct 148980 gggcaggagc tggccagtaa taggctgacg agggaggccc tgctggctgg gcctggtttt 149040 caagtgagca tcctgagctg cggggaccca gggggtctta gagacctcag agctgagact 149100 cgggaccaca gaggggtggg ctgtgctcag ggcaacacag cggatggggc agatgttgcg 149160 aaacctgtct ctctgcctct ctttctcctg ctacagaact ggatcctccc agctcatggc 149220 tgtcaaatcc tttagatgct tctgggttcc atgggcgcct tacactggct tccctgtagg 149280 acagcagacc ctgggggttg gctctgatgg tattcaccat ggggtacccc atgcaagcac 149340 agtgctttca cgcccagcct cccagcctgt ggagtaggcc tgtgtctggc cagcctcact 149400 ttgtggccag aggagggaga cagtggttct ggagacagga gctggcctgg ggctgccctc 149460 ccagcccctg ttctcccagc tcatctcctt gccttgcggg tgctggccac cctccccccg 149520 ccagctccat ccccagcttt ctctgcccga gccgtgacct gtcagtaggg ggcagtggag 149580 gccttgaaag tccttggaga ggactttgaa gcagttttta caaatctgtc cctggaaagt 149640 ctctcctgtc acacccccag cggctccctc cctcctaaca tttttcctgg ggttgtcatg 149700 cagcgggggg tggaggaacc cactaggccg tggatagagc agagccatgt tgacacaaac 149760 cctggctgaa cccacatgct ccctacagcc agcggccgat cactggaacc agggaagtga 149820 cctcatagca agggcccgca gagcagccat cacgcattcc cgatcttggt ttctggaccc 149880 agctctggaa aagaagccag atcctagcca cttggagctg cctagggaag accccagcct 149940 ggtgccggct gacagctcac tggaactttt catctgcttg gccaggtgat gccaaggggc 150000 agaggttaga agtgctaaga agcaggccga gggtggtggc tcacgcatgt aatcccaaca 150060 ctttgggagg ccaaggcggg tgaatccctt aaggtcagga gttcaagacc aggctggtca 150120 acatggcgaa accccatctc tactgaaaat acaaaaatta gccaggtatg gtggtgcacg 150180 cttgtaatcc cagctactct ggaggctgag gcaggagaat ctcttgaacc cgggaggcag 150240 aggttgcagt gagccgagac tgtgctactg cactccagcc tgggcaacag agcaatactc 150300 cgtatcaaaa aaaaaaaaaa gaagaagaac aagaagtgct aagaagcatc tgtcttcctg 150360 attgaaaagc aatctttgct gggcgtggtg gctcacgcct gtaatcccag ctttgggagg 150420 ctgcggtggg agagtcgctt gaggccaggc gttcgagacc agtctgggca acagaggtgc 150480 taggggtagt ggcgcttgcc tgtagtccca gctcctcagg aggctcaggt aggaggattg 150540 cttgagttag gagtttgagg ctgcagtgag ctatgaccac accactgtac tccagctcct 150600 gggtgacagg atgagaccct gtctcaaaaa acaaaacaca aacaaaaaac caacgtttat 150660 cttttgtgat tttaaaaatc acacctactt gtgacaaaat aattaaatta gaaaatgtaa 150720 aggaaatgat caataataat tgcgtcctcc agacaaacac tgttaacatg ttcacgtttc 150780 cttctagtct ttttctacat agacactcaa tacttattaa tttgttttga actaaagatg 150840 gttttctctg ctttgtatga gaaccacctc agccaggcac ggtggttcac gtctataatc 150900 ccagaaagct gaggcaggca gattgcttga gcccacgagt ttgagaccag cctgggcaac 150960 atggcgaaac tccatctcta caaaaaaaca caaaaattag cctggtgtgg tggcacatgc 151020 ctgtgctccc agctcctcag gaggctgagg caggagaata gcttgagccc gggaggtaga 151080 ggttgcagtg agccaagatc gtgccactgc attccagcct aggcaacggg agtgaaatgc 151140 tgtctcaaaa aaaaaaaaaa aaaaaaaaaa gttgccacgt tgtcacctct ctcagggatt 151200 ttcatccttt ctacttttcg cccaagactt gccctgtaaa aggatgaggc caaatagcca 151260 tgggagggtg gtactggatg ttcaaaaaaa tgtttcgtgg ctggcgggac ttagaaacag 151320 gttggggagg tttcagcaga gggtggaccc cagctggggg tggggggcag caggggggcc 151380 cctcacatgc tctctctgcg tgtttcatgg ggctgcctgt gaggccgtgt gaaccagagc 151440 ccggctggga agccacatgc tacctggact ctgacctttc ctggcagcat gaccttagcc 151500 aatacgctca actatgttcc cctctgtaaa atgggctaat agaaatgtcc actcgagaca 151560 tgatgagaaa caaaggtgtt catagagcaa agtgcttaga acggtcctgg catgacagga 151620 gcccacatgt cagtgctgcc gttggcatcg tcatcatcac ggcggcattg gctgctttgt 151680 ttctcccttg tccctgtcac cttcttccct cagcaggctc tcattcactt gttcatttat 151740 tcatggccga ggccccgtct gtgtcaggcc tggtgctgag aacgggggta gagagatggg 151800 ggctgtgccc tgctccctga cccaagggtt ccctttgcaa tgtgaagttc ttggagactg 151860 gaccctcagg ctgttccacc agcccctcct caggccagct taacccttcc gtgctcgttt 151920 tctgagctgt tagaggaaga gagcgggagg aaggatggag tggggttttt gtggggactg 151980 agcggggggt gtgtgaggcc ctggaaatgg tgcctgcggc actcacgcag cattagcttt 152040 tgctgcagtt gctgtttgga gaatattctt ggatttcagg acactgatga cagaaggtgg 152100 aacgcttttt ctggaagcca tcaagagggg accaccgcgg cggctgagca gagttgctga 152160 cttgtgagct gtggcctgac cacagtcact gttctcatga gcgaggcccc ctgtggtccc 152220 cctcccagga atttctggcc ccttggcagg ggacagttca gggctggggg tgggtagtgg 152280 tgtctgcagg ccctcttgga gtcagagaat cccctgtcgc cgtggcgggg ctgttccctc 152340 ctgcccctcc cctcccgctg tgctctcagc tgctccgaca ggatgctttt ggcctgagag 152400 acagaaaccc caactctgaa tggcttcagc cctcaagaga atttggagct tttttgtgca 152460 aaatgagatg ttctgagcat cgaggatgct gtgggggatc ctccatccca ccatctccag 152520 ccgtggtgtc cctctcggtc acaggatgct gcagccacgt tgcagggaag gagagcctcc 152580 cttcctgtga gcctagggag cccctccatg cagccccttc actggccatt gcctgagacc 152640 cgacctggtg gctcctgccc caaggagcag aaagggggtt cgctaggtca gggtggggct 152700 gggtgcgagg accccccccg gccaacaggg tctgcttagg tgtccgtcct gttggggcag 152760 cagggaaggg acccacatgt ggcactggga cacggagagg cttttgtgcc tgtgacggcc 152820 aaaagggatg gcgccccagc cacgttccca cccaccccga ggcccagcat ggccatgccg 152880 gaaatagcag catcgtcccc ctcactgtcc tggcttgctt tcaataggcc agaggggtgg 152940 ggctggagcg ggcgtctgac ctgtggctgg atctagctgc ccgtggacag gctgtgagtg 153000 aatctgcaga ggaagggaga tgggaatgcc gggaccttct cctgcacctc ccgaaccccc 153060 gttccctgtg agttagatgg ggagtgcacc cctgccctcc cctcctgggt atcccctgcg 153120 ccccccgccc caggcacttg atgttgcctg ttcattttcc ctctctgccc ctcccgctgg 153180 cccttcccat atggtcctaa ttaggacctt ccgcccgttg gtggatgggc agagagggga 153240 gcttgctgtg gggcctcccc cgatcggggg acttcccagc acagagcttt ctggcctctg 153300 cagggacgct gtgtgtgcct gtgtgagtct ggcgtgttag aagcgctaag ctgcagctgt 153360 tctgtgcgtt tttcacattt ctcacttctc aaaggccctg ggtttggtgt ctgtgggctg 153420 gggatctgtg ttggggtctc caggaggccc ttggtgggag aggcagggcc ccttcccctt 153480 taatctgggc aaccttgctt tggcctgctg tctgcggaaa gtgccctagg atacggtggc 153540 aggactggct ggggttctgg ctccaggccc agccccagcc cctgtcagac ttaccctcct 153600 tgtgcctccg ttcaccctgt ccacccgcag ggcctgcagg agcatcctga gagttggtag 153660 ggtggcctgc ccggcgtccg cacagggtct gctggtgggt ggctgaggct gcggtgaggt 153720 ctccatggct ccctcgtcct gcacatcctt cccttgttgt gttgtctcgc tagcatatga 153780 gcccgtactg cctctgagtc tgcagcctgt tttccttacc aggtggctaa gcagggtggc 153840 agccagggtg gcagagtccc attggcctgc aggggaccct ctgtgggctg caggtagtcc 153900 cctgtggttg aaggtgccct ggcaggacct gcaccatgac ccccgtcaaa gctcacgtcc 153960 aaggcatttg tgggcacccc cgccccagac gtgagggttg gcatcttctc ttgcacgtga 154020 agcaaaggcc tgtttgaagg agcgtgtgga agcctgggtg tgatgaaggc aaggaccggt 154080 ggctcacccc tcttgcacct ggaccttggg tggcaggcct ggggccttca gtccttaatt 154140 caggagggta gccagtcgct ggaactaaga gtgaacttca gctgttgttg ccatagctgg 154200 agggaagagg ggaaaggagg cgctgcaggg gagcagagac ctcacccttc ctctgccgac 154260 atcaggctgc cggtgctgga cggggccctg gcaaccgtgg caggagtggt gatgtccgat 154320 gatggtaaca agggcttcct gaggaccccg agctgtctta agggctcttt acctggagta 154380 agtatcccct ttaatcctcc caacaacact gtgaaattga ttctgttgtt attcccattt 154440 caccgatgag gaacccacag cccagagatg ttaagtaacc tgcccaagcc tccctctgag 154500 catggcagag ggagggtccg aatgcggaaa gtctggcttc agtgccccca tccctaacca 154560 ctgtcattta cctcttcggc cagccctctg attgcaaaac ctgaggccca gaggagtgca 154620 gtgacttggc cagcttcgca cggcaggtta gtggcagagc tgagcagtgt ctcccatgcc 154680 ctgattctgt ggcttcttga ggtggctcac ccctaaacac gccccccatg gtggctctgt 154740 ttcctcctct cctctgaacc tgccagcctg tgctcaggca gggggagaag tagagcaacc 154800 atgccgggcg ggtcgtcgtg ccccagtgcc gcctgcccta cacctgattg gcagcagagt 154860 ggcccctcct tggtgtggtc tggaggtgcc agtggtcact catcagcaca gcccagtctc 154920 acacatgtca ctcccaaagg atgttgacac agaatgaagc agctagggga ggcggacgct 154980 ttggcacgag ggtggcgttt ctggtaatcc gtagtgctgt tgtctgtggc tgcctttggc 155040 tggcatctca cctcctcctg gctgtcctgc agccacctga gggaggtcag catgtcgcct 155100 tcatcccagg acagtgtgaa tgcagcagcg caagcttgcc agcgccgcac tgcgggatct 155160 ggaggccttt gctcctgagc cctgcctctg tgtaatccct aaagcacgga cttcttaggg 155220 gcttccattc ctccacctgg aaaaacctta caccgtttag ggcttgaggc agggctagag 155280 catggagacg ttgctggagg accaagggag aactgagcgc gtgttctctt ggcctcagcc 155340 tcgtgtgtgt gtttatgcat gggtactttg ccatccacac tggcttccac ggctgggtgg 155400 gagttgagtt gagctcggcg gctgcctttc caccctgcgg gcctggttgg ggagtgtgag 155460 gatgcctgct ggaagccaac gtgcacgaaa gagttaatgg tggatcccat ttcctcagcc 155520 ccctctccag ctttcccagg gaaagggcag gaacagagag gccttatctt cagaggaagg 155580 ggtgggcggg gacacagcgc tgttcggcac agtcccctct gagccaccct gcatgtttca 155640 ttccaccgac ttctgcagcc cagctgttca gagcggatcc agaaggtgga gagagggttt 155700 ccaataagca gaggatggag tgaatgtgag attcattact gggatttggc aaagcaaaga 155760 gcctcacttt ctccccgcag atgggacggg ggcggggctg gagccagcgg ggtgggggta 155820 tccagcaaga gctccttccc atcctcccac ttcctttgcc atgggccccc tcctccacgc 155880 agaccctcag cctggaatga tcagtgtcca gcttttctcg cccctctcct gccccgctgg 155940 agggagtgac ctggcccctg gccccggcca cctacacctc ctgttttgct gcactagcct 156000 cgtggtaggg gctgcggcgg aggtgggcaa aagccgcttc cgggcagcca gcccccatcc 156060 tgggagtgac tgaaagtcct tgggggttcc tgcagggtga gctgcccatt ctggccctgg 156120 taaggacacc caggagaggg ccagggtgcc tgtatttggg gcacagcata aagaacagcc 156180 gtaagtgttt ctcaggcagg agggtgccga agcattggga agctgggatt tagaagcatt 156240 gtttggggtg gtgagtggaa gatgcaggac acagattcac gcgattgtgc agatcacctg 156300 gcctcactcc ctcggtttac agtggaggaa actagaggcc gagagaggtg aagtgagttc 156360 cctggggtca cacagcctag ccaggcccag ggcgccgacc tcctgctctg ccttcccgtg 156420 cccattcggt tggcatcagc atccctgcct tgacaccccc gtgtggcagc tgctgtgatt 156480 ctgtgactcc tcctcacccc accccagtgg ggccctgcga gggaaagaag aatgccctat 156540 gcagaagtgg ttggaaagca agaagcctgg agagaagtga ggcctctgtg gtttggcctg 156600 agtccaggac tcatggcctg gttcccaggg atggagcacc gacccctccc ttctacaccc 156660 ccaccccacg cccccaggag ctccctatgg ggaagccgga atggacctgg gctcagagat 156720 tgtaaattca tcttgctgga tgtgtggctg cctttatgta accaactctc tcacggagaa 156780 gccaggggat ggctctcagt actctcgggg gtctctcagt gaggtgggag gacctcgaga 156840 ggtcaggagg ctgctcaaga ccttctgccc ctcagggacc aggtgagggc ttgtcgactg 156900 ctctgacctc ctgatgcttc tggtggggag acctcagagg ggcctgccgt caccatcgcc 156960 agtggccctg gcctgcccag tcatccttct ggggtggcca aactccatgc tgcaaaagcc 157020 caagtgaacc ccagtagtgg cctgggagaa tcatctgtca cgagccaagg atggagtttc 157080 tggggaggac tttctgctgc cccccaaccc ctttcgggta cattctcctg tagccccact 157140 ccctgtaaga aagtcaggtg cctcccgaag cttctccctg gccccaggcc agaggtgaca 157200 gtgggggccc cttgcttgcg ctggtgactg tggctggttg ttggtgcctg gccctgccct 157260 gcactgtgca cccattgaag gcggcatcat ccgggcctct ccggtggcca tgcatgggtg 157320 agcagcccac gacacatctg cttccagcat cgtgtgggcc ggggctttca gaggggctga 157380 gggcttggat ggccctgcag gggggtgctc ctggccttgt gaccgaaagg agctgaaggt 157440 ttggagaagc cgttgggccg aggtcagttc ttatagattt ggcgaggagg gaacagatgc 157500 tcacggagct gctccaggca ctgcacacac tgcctcactc tgcgctgaca gccaagaggc 157560 tggttccccg ccgaccccca ttttacagat aatgtgctcc cccagttcct tagtggtgga 157620 gccaggattc gaacccacgc aggcagcctc ctgggcctgt agtcctaccc ttcatctccc 157680 tccaggacct atgtcttggg gttggcagga taatgactcc cagagttgag cacatcctaa 157740 tccccagcac ctgggactac gttaggtgac atggcagggc cagctaaggt cactaatcag 157800 ctggtcttaa aatagggaga tgatcctgga tgatccacac gggcccgctg tcatcacaag 157860 agtttttaaa agcgcaatag accatctgag gggtgcagtg ggagaggctt ggaaggagga 157920 aggaggccac aagccaagaa atgcaggtga acagaaaatg caggaaaacg cagtctcccc 157980 tgcagcctcg ggagggtgcg cagccctgtg gacaccttcc ctgtagccta gtgaggtgga 158040 gtgtgggact aatctgtgtt gtttgacatc acaagtgtgt ggtcatttgc tacagcagtg 158100 atgggaattg aatgccatta ggcagcagtg cttctatccc ggaagaatta ggataaattc 158160 ccctgtggat ctcaagctct gggagattct gggctcctct ggactgctcc agttctgcaa 158220 tcataggaaa ggtctcccat gtctgtttgg gagaagaaaa ccccgtagca aatccatttc 158280 cccttttgac aaatgaaggc gagggtgtgg gctggacaca tgtttccttt ttgtggattt 158340 tttttgtttt aacacttaga attctgtagc tgaaggagac tttggggggt tgtctgcctg 158400 atttgcaagt gaagaaatgg aggcccaggg aagttaagtg actggcccag ggtcatgcag 158460 agtcatgctg gaatatcaag ctagatagcc cagttcctgc tccaaagtgc tttcctccct 158520 ggttggggag gagggttgga gggagtggac cccgagcaac agcagcattg gcaggggttg 158580 gaagagtagc tactgtatcc aggtgctgga gcctctggcc acttcctgca ggaaccaggt 158640 gacccaccat ggcacaggcc tctccctgtc tatctgcagc cctgggggcc ccagggacca 158700 gaggacactc tggcctgagg gctggggcct gagagaagag atggaagtac ccctagtctg 158760 gcctgccccc gtggcgtcct gcaggcatat ccggcagccc aggggtccta gagaacttgg 158820 ctggtgggcg tccccacctt gccgcagctg caccctgtgg ccagcagctt gcaggacttg 158880 ggctgttgcc tgtggccctg aaacagtcat tttctgagct gagtggggat caggtgagca 158940 gatccccaca ccttaactgc tgtgatcttt ctgtcctgga ggctggtggg cagcctggtt 159000 ggtgcttcat ggcactttat gaccggccct gtcaccaggc tcgtgagttg ctcccctcct 159060 ttcgggcatc ctgaacggct tccctgagag ccccgccctg ggccttcgcc tctgcaggcc 159120 cccgctgcct ggggcgcctc cttcccctgg aagctgggcc tctttgggga ctcattaaga 159180 agggccttgc cgagtgctgc caaattgccc catctggtcc ccatttgttc cacttaccac 159240 cctattttaa cttttatgtc tcctccttgg ctctaagatc tgagcaggca gggcctgtga 159300 ggcaccccag gtcccctgat gctgccagca cccaggggac tgttagtaca tatgcaggga 159360 gggaaggaat gaaggaagag atgacttggg gagtcctcca gttcccattt gtaactggca 159420 cattgcgaca aaacactcat ggcattttac ctttttcata tacctttttt ttaaatttat 159480 ttttatttga gatggagtct cgctccgtca cctaggctgg agtgcagtag cacaatcttg 159540 gctcactgca acctccacct ctcgggttca agcgagtctc ctgcctcagc ctcctaagta 159600 gctgggatta taggcgccca ccaccacgcc cggcgaattt ttgtattttt agtagagatg 159660 gggtttcacc aagttggcca ggctggtctc gaactcccga cttcaggtga tccgcctgcc 159720 ttcgcctccc aaagtgttgg gattacaggc gtgagccact gcacctggct ttcgtatatc 159780 tataaaagag aatttgccca gaaaatcttt cagatgcacc tttagggttt taaggcacag 159840 atacatgaag cttgtcagtg agcagctgct gcttattcct ttttctcttc caattcagag 159900 cggcctgcgt cccaagcgga cagctgctcc cttcctcttg gctccctgct gcccacgctc 159960 ccacagaagc agggagaaga ggcaggaagg tgacgcgtga tcatccgctg ggcgcccgca 160020 cagtgccgtc tgcacaggtg ccatctcctt tacttgtcac tctcctcgct gagccctttc 160080 ccctttttgc agatgagaga gcattgcctc ccagaggtta agaaatgggc ccagagtcac 160140 tcagctgatc agcgtgcagc cagatttgaa ccacatcctg ctgatctcca tgcctgcagg 160200 cctggcctga tgagatggac agctgggtgg tggagacctt gagaccctgg atggctccca 160260 aatagggcct gtagctcctg gacagggaga gtctggcaca aagggtttgt ggagtgagct 160320 gggggagaag gtggcttagg gtccctgtct ctgaacaaac agatggaggg gctattccag 160380 cgttttctca gcctctggtg tgctgggctc ctggttctgg gaggagagaa tggagctggc 160440 ctccattctg ggctgggctg gtttgggccc aattcagaca agcttcttag tttgccatga 160500 gtgacacttt tgcctgccct ggtgtctctg ccaaaaatat gaagggtttc agaaccccca 160560 ccccggcctg cttccctccc agacttggag tgggtctggg gctgacaaca gtctcatgcc 160620 agatagcctg agcagccacc agtgccatca ggtctgacac tgcggcccct gccccggagg 160680 gaaaaacaag gccctctctg ggggattttc tgccagcttg tgaaaacagg cctggagtca 160740 gccagcgccc ccatgcttag acacttcgtg tggttttcaa agtgctttta tgttgctagc 160800 tcatatgatc ttccccaaaa ccccataagg gagggcagga agtttgagca acagcctgtc 160860 aagcacccat acagcaggtg gtttcattgc cctccattta cagacaagta aactgagctt 160920 cagggtggct accgcttgtc tcccaagcca cccagccatt tagccacgga agaggtcatg 160980 actttttaca ccccagtgaa gctgaagatt tttctttccg tttttaaaaa tgtttactcc 161040 ccagggcagt gaacacctgg tgcctctgtc tagcgcaaga ggtgaacgtt tgccacttcc 161100 gtttctttcc tcctaccaga cctgaccctc cttttgtgac gggaacatcc tgcaggcagt 161160 ctgtcctgct ttcatagact ttgagaaacg gggtccaaat tgccggctgt gggtgggaca 161220 ggcgacactg cagtgaagag gtggagtatt tttgtagcgg ggaagaaata catttcctct 161280 accctcttag gttcagtgtt tgggggtctg tgaattaaac tcactcaaga taaattaatg 161340 agagaaaaga cagatttaat cacatacgta tgggatttca ctgaaaaacg tgactcaaaa 161400 gagcaggtag aaggtggggc ccgtgactgg tccgaaggta gtgagttatc tcagttgatt 161460 gttcacagtc agttacagat tagactcctt gttccactgt ctcccctctt cccacttgtt 161520 ttgttttttt tgagtcagag tcttgcactg ttgcctgggc tggagtgcaa tggcacgatc 161580 tcggctcact ctaacctccg cctcccgggt tcaagcgatt cccctgcctc agcctcccga 161640 gtagctagga ttacaggcac ccaccaccac gcctggctaa ttttttgtat ttttagtaga 161700 gacagggttt cactatgttg gccaggctgg tctcaaactc ctgacctcgt gatctgccta 161760 cctcggcctc ccaaagtggt gggattacag gcatgagcca ctgcacccag ccaactagtc 161820 ttaaaaaaaa aaaaaaaaaa aaaagaactt agggcccgta tactatctta ataggaaaaa 161880 aggaaggggt gaaagcacat attatgggcc gggtgcgatg gctcacgcct gtaatcccgg 161940 cacttcggga ggccgaggca ggtggatcac ctgaggtcgg gaattcaaga ccagcctggc 162000 caacatggtg aaaccccgtc tctactaaaa atacaaaaat tagccgggta tggtggtgca 162060 cacctgtaat cccagctact tgggaagctg aggcaggaga attgcttgaa cccacgaggc 162120 ggaggttgca gtgagctgag atcataccat tgcattccag tctgggcaac agagtgagac 162180 tgtgtcttaa aaaaacaaat aaaaaaaaaa aagcacatat tatggcaaaa caaatgagtt 162240 tttggaaaga taaataggcc cttaggagct gagatgggag atgtgaagtc ttgtgacaat 162300 gtcttcttag gtgtggtgtg gaaactactc acatcttcca gggaagagtc agttgctccc 162360 agggagcaga tttgggcctg tataccatct taatagggga aatggaaggg gcaaaagcac 162420 atattatggg ctgggtgcaa tgtgcccagt gcaggaggca gacgtggttt atggttgctg 162480 ttgaaaccag tgcagggccc gattgctttg tattgagtgt tgaggatcct ggttttgtat 162540 cagccatgag tttgcagctc tgggacacac ttgatgttgg ctcaagggga aatgaggttg 162600 gaggggcagg gtggttggat tggatgtggg cctggggcca ttgctgatct acaaagtggt 162660 catcacacgg gaataataga gctggctaca gaccacaacc agcaatatta tttaaaagta 162720 aggtcacact tttaataata agtcacattt taagttatta tcaatttata aaacacactg 162780 ttggtataat gatagctttt caagaaggat ataaaaaggc atgttgggct gggtgcagtg 162840 actcacgcct ataatcccag cactttgaga ggctgaggtc ggcggatcac ttcaagccag 162900 gagtttgaga ccagcctggc caacatggtg aaaccctgtc tctgctaaaa atacaaaaaa 162960 aaattagctt ggcgtggcgg cgcatgcttg taatcccagc tacgggggag gctgtggcag 163020 aagaatcact taaaacctgg gaggtggagg ttgcagtgag ctgagatcgc gccactacac 163080 tccagcctgg gcaacagagc cagactccgt ctcaaaaaaa aagaaaaaaa agaaaaaaag 163140 taaaaaggca tgttgaaggt acctgcttgt ggaaagttgc aacttgacgg gaggtagggc 163200 gagcacttct tagaaaggtg gaaatgggcc ctcctgctac agagacccac aaacatagac 163260 tgaggcctgc agcctaggag actcaaaaga ggcaaaggtg aataagagtc aaggtctcca 163320 agtcagggtc tgactctggg ggtgggggtc acatatgatg gaggatgtca ggagggcttc 163380 ctggaggtgg tgacatttac caggggggat tttaggtggg gtttgcgaga cagtaggacc 163440 tggctgaaga gcgtaggctc cttagacagg agtgggaatt caggcttgaa aatgagttgg 163500 ccagattgca ggggtcctcg aatgcaaggg aagaatttca actttaacag aggagcctgg 163560 gaagctgttt gggaaaagga gtgataaagc gggaggggtc ctccagcaga gccctgcatg 163620 ggcaggaggg agcgagatgg gaggtgggtg ttggtaaggg atgatcccag tggtccaggg 163680 gagcagtcat agggtggaaa ctaaccttgt ggggtctggg caggaaggga ctgatttgag 163740 acaccgggaa gaaacagcca gtaggacttt ggtgagaggg ctgggggtcg gggagggggg 163800 tgtggagagt gggagcttga gtctctgaaa acagacagtg ttccaagggg gagacctgag 163860 gcaagatgtg gagaggcagc tgagctggga agctggaacg gaggtgtggt cactccagga 163920 gactaagtca gggggcgagg ggacccttgg gagctatcta gaccccagca ctagggaata 163980 cggaggggag aaggagggga gaagaaccag ctggtgcgtg tcaggcactg ccctcgaggt 164040 cagatggggt ggggctggat actggccatg aggatttttt caagagctgg gttaatagtg 164100 agacgggcgg acaccagatg gctcgggcta agaagtaagt gggcggtggg aagctagaag 164160 ccgtggtgta gacctacttt gagaggttgg gctgttcaga cagggagaaa gttcacagtt 164220 tgaggaggta gataggtcaa aggaagaggg tttgcttgtt tttgagattg gggcatcctg 164280 aacgttctcc caggccaagt gagaagaaac cagaagagga acatgtcacc caaatgtgct 164340 gaaacagccc agcagctgcg ctgcctcaca gaaaatgtgc agaggcccct ctgtcccacc 164400 atgcctgcct ggggacggcc ttcactcggg ctactcaggg tttccccagc ctgccaaccc 164460 aagggtggca ggagctgtgg gtgctcccag ccccttctca aggttggtct gtgggtagaa 164520 atgtgggctg cctcggggcg tcacagctac aaatgcatac cagccctcag aaccacattc 164580 ctgctcccca gccctttcct ccgcaccccc atgcagaagc gcggccgcca gctcacaaag 164640 gatagggagg gatattgctc ttggcatttg atgggaagca tctgctgcat cccattgggg 164700 tgttgcccag gatggattgg aaaagagttg gcaggaaggc tgagctctgt gctcacaacc 164760 tggcttggtg gtggccgagg agcttggcag gagcagagtg caggacctgg gaactggggg 164820 ttggtgcatg tgtgcacgca cgtgtgtgtg tgtgtgcgtg cgtgctgggt gggtagggag 164880 gaagctgtga aaccacatcc cctcctctct gctgctgtgt tgctgtgtgt ttcagcagca 164940 cgtgggtgtc accacacttc ctagcaggtg tcaacctcca agactgttct gggctcttct 165000 cccagttggc tgagttggag gtgggagtcc caactgtccc ctgtggcttc cagagtggga 165060 ccttgctgtg ggataggctg gccaatggtg ctccctcccc tgtgaccctt ctgttgggtg 165120 ggtcacgagg aaggactgtg ggtgttgccc acagacaggt ggacatgtgg caaggacacc 165180 ttgggacctt ctttctgacg ccccttgaag ggggcacttt ctcagctttg agatgagtct 165240 ctgtggatgt gggaagttca ctatctcaag agcagcagcc ttggaaaatc caacacagaa 165300 ccccgagtag gggcgggaag gggtcctgtc ccgctcactg gctgcctggc agagttctgc 165360 acaaggaagc gcctgtgttg ctgtgggcgg aggaatggac tgagggctac attcgcttcc 165420 tgttgccgct gtaactgctt atcacaaact cagtggctta aagcaacaga ggctccttcc 165480 tttacagtgc taagggtcag aagccgatca gtctcaccgg actaaagtca aggtgttggc 165540 agaatccatt cctgcctctt ccagctttgg gtgggaggct ctgctggagt tccttggctt 165600 gcggctgcat ccctccagcc tctgcctcca tcctcctaca gcctcctcct tctctgcagt 165660 cagatctccc tctgccttcc tctttttttt ttttgagacg gagtcaccca ggctggagtg 165720 cagtggcaca atcttggctc actgcagcct ccgcctcctg ggttcaagcg attctcctgc 165780 ctcagcttcc cgagtagctg ggattacagg catgtgctac tacacctggc taatttttgt 165840 atttttagta gagacagggt tttgccatgt tggccaggct ggtcttgaac tcctgacctc 165900 aggtgatctg cctgcctcag cctcccaaag tgctgggatt gcagccatga gccatcacac 165960 ctggcctgcc tccctcttaa aggacgcttg tgatttgggg cccacctggg taatctcttc 166020 atctcaacat cttcagttac atctacagag tccctgttgc cacatgaggt aacacagttt 166080 gggaagggag agttattcag cctaccctag gggcctgtgg tgtatctcag ggcccttctg 166140 attttaagat ataaagcaag aaaacaaact ggctcaaggg gaaaaaagga cacgttgaat 166200 tctgttgctt taaatgtata tttttttatt gtgctaaaat gcacagaaca taaaatttgc 166260 cattagtaac actgagtaca ttcacagtgt cgtgcaacca tcagcactgt ctagcgccag 166320 aactttttca tcaccccaaa gggaaacccc gtatccatga aggactcact ccccattcgc 166380 cctctccagc ccttggcagc caccagaatg ctttctgtct ccataaattc atttttaata 166440 agtgcaattc tgtgtgactt taaaataaat aaacatgagc acgatgagtt gcttattgga 166500 aggatatcca tgcggggagg ccggcgtgtg gagtgcgtag gcctccggac gggcaggagt 166560 tgaaggggcg tggatgtgcc gccctctcct ccccttgctc tttccttggg gtcactgcct 166620 gagtatccct ctttgcaaat ggccccaaat aatgtctcag cccccacgtc tgcatcgcct 166680 cctagcttca ggaccctcca ccaaaaaaca ttccaagctt cagactcact cctgggaaaa 166740 ttccaatggc ctcactctcc cttttgagcc agccagatcc catggcctgt ggcgggctgc 166800 ctttgagtcc tgagcacctg tgagctaggg aagcaggaca ggcacaccca gggaagggga 166860 agagtcgtcg tcagtcacag taattgatat ctttggaatc gtctaagaga tacttagcgt 166920 gtgcctaaaa cattcatttc tttttttgtt tgttttttga gacgaagtct cgctctgtcg 166980 cccaggctgg agtgcagtgg cgtgatctca gctcaccgca acctcctcct cccgggttca 167040 agcgattctc ctgcctcaac ctcctgagtg gctgggacta caggcacaca ctaccacgcc 167100 tggcgaattt ttgtattttt agtagtgact gggtttcacc atgttggtca ggctggtctt 167160 gaactcctga cctcaggcaa tgtgctcgcc ttggcctccc aaagtgctgg gatgacaggt 167220 gtgagccaac acacctggcc acattcattt cttaggagaa gctctgcatt ttctgaaagt 167280 gaaatgtccc caggcgggtg acactgatgg tgggatctgt ggcctcacca gtgtcttatg 167340 agagatgccg ctgtgtgttt caccaagctg tatcctattg tcctctaaat gtggcttgta 167400 gacatggtgc cgagaatgat ctgggaggtt caaatcataa tatggtccaa atcaacagct 167460 ctctgatgac ctggtattat cctaggatca aattgagact atccgaggat gggcgtggtg 167520 gctcacgcgt gtaatctcag cacttcagga ggctgaggcg ggcggatcaa ttgaggtctg 167580 tagtttgaga ccagcctggc caacatggtg aaaccccatc tctactaaaa atacaaaaag 167640 tagccgccgg acatggtggt gtacgcctgt agtcccagct acttgggagg ctgaggcggg 167700 agaattgctt gaactcagga gacggaggtt gcagtgagcc aagatcacgc cattgcgctc 167760 cagcctgggt gacagagcaa gactctgttc cccggcaacc aaaaaaaaaa aaaaaaattg 167820 agactctccg agctgcactg tccagcatga tagccactgg ctgcacgggg ccatttgaac 167880 acctgaaatg tggtgattcc aagtggagag gtgccgtgtg tgtgaagtgc actctgggtt 167940 tcagagtcct agcaaggggg aaagaaaaga atatcaaata tctgtcattt ttacattgat 168000 tacatgttga attgataata ttttgggctc tgttaagtga atgatattaa aattaatatc 168060 acctgttctt acatttttta atgatttcct ttttcttttc ttttcttttt ttttttaaat 168120 atggggtctc acactgttgc ccaggctgga gtgcagtggc acgatctcgg ctcactgcaa 168180 cctttgcctc ccaggtttga gcgattctcc tgcctcagcc tcccaagtag ctgggattac 168240 aggtggctgc taccatgcct ggctaatttt tgtattttta gtagagacag ggttttgcca 168300 tgttggccag gctggttttg aactcctgac ctcaggtgat ctgcccacct cagcctccca 168360 aagtgctggt atgacaggcg tgagccactg tgcctggctt gttcttacat tttttattgt 168420 aggtgctgga aaatgtaagg ttgcgtctgt ggcccatgtg ccgtttctgc tggagggttg 168480 gaccgagggc cagccgagaa ggctctgggg ctgctctacc tgaatgctga gtgtgtgctg 168540 agcggtagag aactttgaga agtgctgaag gacagaggct ttgtgtgggg gatgcagccc 168600 caggccggag atgccttctc tgtgctctgg agaccctcat ttggtgacag caagaggaac 168660 cactgcaaga ggggcggcca cctcagcaaa gcacccagga tgctggcctc ccagctcagg 168720 aatccagagg cagaggaggg gaggaggctg ggcttggagg agagcagggt cttgggccct 168780 gggaaaagcc tggggggcca gaaagctggg ggacagattg aggccagagg caaagagaag 168840 aaggttcgga gaggagggcc aaggaagaag ggttctgccc acggggaggg agaggcccac 168900 ggggcagggg cgtggtggga gctgcatcct cgaggctttc tgttgaccct gacacctggc 168960 cagaaaggag ttccttctgg catcctttgt cagcggtttc tggagctgcc ctttaggggc 169020 cagtgatgag ggtgccctgg gctgggctgc agacagtgga aaagacaggc tcttctcact 169080 cccagtgctg gggaaattag cttcttggag gaagggggag ctgtattttc tgagtggccg 169140 cacttcctgg cctagacgtg tgtgtcttgc tgtaattttg gcgactggtg ttggtggtgc 169200 ccattttatg gatggggaag gtcaaattcc acagatattg agtgacaggc ccagggcctt 169260 ggatttcagt gtttgactca gaacccaggt ctctgatctg ccaccagcct ccctcccatt 169320 cagatgggaa cagggactcc gggcatgcag tcttctccca gacactcccc cggctctggc 169380 ctggcgcccg gagaccagta gcagcagctc cccacggccg ttcactgtga gggtggggag 169440 ggccgtggga ccaggaggcc ttagggggaa agttggccat gaggagtggg aagcgacggg 169500 tcagatgcca gtgactgctg gctggggagc cgctggacgt ggctggcctg tttggccagt 169560 gtggcgggtg ccccggggct tcagtcaccc ccagccacgt gtgggggtgc gggatgggaa 169620 aggtaagagt gtgtggagcc cagtcagcac tcaacatgag gtcccgtggg ggctgcctga 169680 gggcgtagct tccagaattc agcccctggc cctcagaagg tgtcaccaaa ggcttctttc 169740 catttgagtg aatccctccc agcccccagc aagccctcgg aacgagccca ctcccaggcg 169800 ctctctccta gtgtgggagt ggccacgccc ctgctgggag tgactcactt gggttcagag 169860 gtcgtggcac tgagatgggt ctggcagatc ccagcgtcca ggcccagccc ctatagtgtc 169920 agctccctcc tctggggacc cccttgcttg tgcccctctg ggtcccagca catcccaggc 169980 ctgcagggag ggggagagga agagactgac tcactggcca ggtcccccag gggctggaga 170040 ggctggagag gcaggagctg gatcagatct gaatccagag gctctcggag gaagagctca 170100 gggtgagctg cgcccccatc ccctgcccct cctctcctgc tccttctccc ttccatggtc 170160 ccagccagca agcacctggg gtagagggga caaacccagg tggctgtgtt ccagccctgg 170220 ctgcaggtct gaatggcttt ctggggtggc tggccatgct ccctgagagc ccagctgtgg 170280 cgatgtctga gcaggtaggt gggggagcac ctaggaagca ggggtgtcag gcagagcaca 170340 aggagagagg gtgtccaggt cagtttcagg acctggctga gaggaggggg ctcctcacgg 170400 gcaccgcctc tggcaagcac agggacaagg gcaaggacgg catggccaga ggtccctggg 170460 agcctcttcc cctctcttct tcctagcagc tccccctcac tcttcccagg gaccctgtca 170520 ctttccttta gcgtgtggca gctccttggc gtccctcccg tgccttcagg ttgcttctgc 170580 gccgggcctg ccgctgggcg cccctatctc tgcctgcccc ctcctcctgc tcccctcgcc 170640 ctgccccctt ggagcaattc cccaccgagc ctcccttccc aggcagtcga ggtccctccc 170700 tacctctgcc ccgcgctctg ggaggctcct tgttccgcga ccacaaagcc cctttgatcc 170760 tctgctcggc tctgagccat gtgacccggt gggcgggccg cggctctcgg cgcgtccagc 170820 gcagcccgac gttccgctgc tggggtgagt cctgctcctt tgttcttccc agccttgcac 170880 cactggctcg ggggctctca ggtggcgcgg ccgcgaggcg gaccctgatg gccatggtgg 170940 cggtgccggg agccacgctg tccctgggcc ccggcccgag gccggcagga ccgagcgggg 171000 tccccaggag aggggtggcg gggagctcga tctccacgcg gggaccagat tttcggcctc 171060 aaaatagaag aatagggctt tgtgtggtca cagctatctc tttgtaaata tttggccaac 171120 taagctgagt ggctaagttc tcctgctgcc cggagcttct tggaacatgt ttccttttcg 171180 caaggggttt ccctggcttc caggagggcc aggaagaaat tcgaattggc caccgctttc 171240 tctaaaatca ctccgctcaa gttatcaccc ctctgggctc ccgaagaccg gctggctgga 171300 ggctggagat agtctcaatg ctcgaaatgc cgtaaccgaa gctccccgcg gcgccggcac 171360 tgggatccag ggagctgctg ctacagcgca gctctggatt cctggatgtg ttggatatgt 171420 gcagggcgtt cctgggagga gcggggaggg agggtgctgc tggcggggct ggtctgcgtg 171480 tgctttgctt ctctacaatg gcatgctgcg tgtcggccat gcagaggcat gtcagtgagc 171540 aggggctgag ggatctccct aacggacctg ctttcagagg gtcttttcat gctgggagaa 171600 ccccagagac taaatcatgc agccaacggg gtggtccccg gcctcaaagc agggaggggc 171660 gaggagcttt gtaggcaatg ccatctgctc ctgaaacgcc gtcccagtga ctctggggac 171720 tgactcagcc tccagcctgc tgcacttcat ccctggcccc tctctctttg ctttttcatg 171780 tgaaatctgc tgtgttttgg tcagaggttt ggggaacagc tctctgctca tctaagataa 171840 gtttgtaatt cctttcctgg agaaaaatat gccacccgga agcaggttga gcagtggttt 171900 tctggcaggt ctgttcgggg ctgtggagac agcacctgct ggatcaggat ggagttggaa 171960 tttggtttgg atcccacatg agaaaacccg ttggaagagg aggaagcaga aaaaggcccc 172020 attccctaat aatgctgtgg gttttcctcc tccattcatt gccaccttgc cttgaaactt 172080 aatggggcca cgtgtgtttc catgaatgtc attctctttg gccaactccc ccggcagccc 172140 caggagctcc ttttcaggaa aaggaagaag gtgtttgctt agcatctagt atacgagtcc 172200 ttgttggaaa ggtgggattc ttgtttctcc ttgggtctct tttaggctga gatgtggtca 172260 aggaaggcct gtggtgtggc tcgccttttt taatgctcgt ctctggagac ctgagttgct 172320 gctgactccc agcttgcccc ttctgtcccc tggccatttc tgtgtcgggg tggctgagac 172380 actattgcat tggccacttt gtgttcccac tagcccccgc ccctgtaggc tgtcattgtg 172440 atggtgatgg ggccaattca gctgcggtgg ggaggaccca ctgtgtgcgc ctggggggtg 172500 gcgtggggca ctctgggatg agaagatgcg acttctgccc tgagagccct gctttaatgg 172560 aaggcggggg catagttgca ggcagaagcc atcaagcact gtggtcagac cagcattcca 172620 tgtcaaaaat ggccttgttg gccgggcgca gtggctcatg cctgtaatcc caacacttca 172680 ggaggccaag gcaggcagat cacctgaggt caagagttcg agaccagcct ggccaacatg 172740 gtgaaaccct gtctctacta aaaatactgg ctaatccggg catggtggcg cgtgcctgta 172800 atggcagcta ctcgggaggc tgagacagga gaatcacttg aacctgggag gtggaggttg 172860 cagtgagctg agattgtgct actgcactcc agtctgggca acaagagtga aactctgtct 172920 caaaaaaaaa aaaaaaaagc cttatctggg cctgggatct gtcctccgaa cactgggtcc 172980 actgtgctcc acaaggactt tcaccccgga agccctagac ccacttgggc aaccagagtc 173040 tctgggttga ccactcccca gccctggcca gcctcctggg ccaccgtatt ctcccaactt 173100 cctgttgtgc cacggctggt ccaagctgct cttatcagac aatgcgaggc acttccacag 173160 gaggggacaa ccccgtcctt aggagcccct tctccctgcc cccaggcctg gtgcagtgtg 173220 tggcttccct gccggtgtca aaggtctcaa ggccccttta agaagcctgt caccaccacc 173280 agcagcttcc gttatctggt tcttctgtac atgtaagcct ttcccataca ccccggatgt 173340 ttagggcttc cgccctctct ccctggccgg gagtgtggga agagggcttt atttcaatgc 173400 ttgagagtag ggtcaatggc cagggtaagc tgtgggggct cctccccgcc ggcccctctc 173460 tgcagccctc accttaacac agagcatcga taccacctgg gctttgggaa gacctggagg 173520 ctgaccaccc tggaggctcc cagcgtccca cagccactct ttggggaaga ggcttcctga 173580 gggacttgtg gcccttggct gggactctag tcccagagtt ctgccttccg gcgccgagct 173640 ttgatttgtt tattgagtgc cagcccggtt cccggacagg tagggacctg ttcccggagc 173700 tcagcagagc cttgggaagc tttcccagga gggctcccga gggtggcggc catgcccagt 173760 ccgctgtacg tgtgagtttg tttgatgagg aattggctgg gaaggcgcgg gtctaattac 173820 aggcccatga gggtccctct cgcccccacc caggaagcag cggagatcct ggcacactca 173880 gcacctgggc ctgtgcctgc ccagctgctg gtggaatcat gggagccttg ctccggggcc 173940 tgtagagcag cagtgggaac cttccccacc tcagcccctc ccagagttgg ctgttcaaac 174000 tcgccgccgc tcagcctctt cctcctctct ttcatcaacc ctgggaatcg cacactgccc 174060 accccaccgg gccccggagc gggtgcagga agagagagct taacacccag aggtctgggc 174120 cttctgcagg cgcctgagct gctgtggcct gagctgggtt ccctgctgga accatcacag 174180 tagacctaat gatctgcctg caggagttgc ttcatcccag ccgactccgg ggctgcggga 174240 aggggctggg ccttggtttt gctgggggtg gggggtcagt gcaaagggcc tgaaaagtgg 174300 cagaggtgat ggcccatctg tcctccccct ggccggccgg cctaaacgcg attggctctc 174360 tttctttttt ttttttccct cccttttccc tataaataac actaaatgcg atttgtcaat 174420 gcattcattt gggttcagta gttggaccat gggcagaagc actccagatt tgtcactttc 174480 cctaagctaa gggtggggaa caccctctgt gagatcttgg ctcctgagcg cccaagactg 174540 ctcttggaac cccaactctg ggtcggtctc aggggactga cgttgatgga gttgctgaca 174600 ttgacctccg gcctctgcat ggccttcagg aagggggccc ttcgctctct gtcccgtcga 174660 gcctggctgg cagcactccc ttctcaggcc tgtgcccccg gcagggcctg ctgcccccgc 174720 cctgctctgt gggtgccagg ctccaagcac caggtgactc ggtcactgaa tggtcactga 174780 acagtcatcc ttgctggtgt ccccagtgga atgtgcatgg acgtcctccc tcccccagat 174840 ccttgtcttt tatctctcag cctttgttcc aggggccacc acaggaccag gaggtacgca 174900 gacgtgggtg gcacatccac tgggcagatt cagccctgaa cctgcacgcc ccctccaagg 174960 gggcccccag cgggcggggt tgatggtgcc gtctctctct ctgtcactag aacggacatg 175020 aggattgtgt cttgtcgatc cacgtcctga gttcccagac gtcataggtg cttgctcaac 175080 gagtgtttga atgaatggtc agcattgtgt gaccgcagat tttcaacttt tatccaaata 175140 gtttgtggtt tctgtgaggc tatcccgaga cagtctcaca agaatctcca ttctccctgc 175200 acgctccgca caaggtctcc ttggggggtt tttcagaaaa agggccaaag agcagcattt 175260 cctcggggat ttgaacacga tctcccccgg ggcaggggac tgccctggaa gattcccggc 175320 accgcttccc atgcgccacg tgactaggag ggtcttgggg caggatggtg tcttttgtgc 175380 cttgtgtgct ggggccggag gaaacactgc ccgtggccgg tgtcatctgc cagccctgaa 175440 gactaatgat gggctggaca gtggccccat tgagtgggag ggagaatcgc tgctgtctgt 175500 agctgggggg ccgggtgggt gggagccgag gccagggaga acagcgcaga cctggcacgg 175560 agaggcctgg aggaggagca gggggtctca gccacccagg gtgcagggac gccacacgag 175620 gagcaggtgt ggtgtgcgtc ctcctgcggg ttctccacct cttggcttcg ttacctgcac 175680 taggctttgt ggtgagaggg cacagagtgg aggaaggtgc cgtggctagg gcaggccaca 175740 cgctgtgcta atggattgct gttacctgtc gcctctgtgg ttttgctgtc aggatcctcc 175800 agcaccaggt ccccaccacc aggtatgggc cccacaggca ctactggctc cccgaagcca 175860 gggacagacc ccatagacaa tactgagtcc ctgcagccag ggatgggccc ccacggccag 175920 taccagatct cagggaccag caccgggtac ccacagccag ggacaggcct ccatggccag 175980 taccaggtct cagggaccag caccgggtac ccacagccag ggacgggccc ccatggccag 176040 taccagatct cagggaccag caccgggtac ccacagccag ggacgggtcc ccatggccag 176100 taccaggtct cagggaccag cgctgggtcc ccacagccaa ggacaagtcc ccacggccaa 176160 taccagatcc cagtgaccag cactagatgt ccacagccag agatgggccc ctatggccag 176220 taccaggtct cagggaccag cgctgggacc ctggatgact gaaggagggc acggttgact 176280 aaagctgcag gagccagcct ggccatcctg aggcactaag ccatcactgc ggtctcaggg 176340 gactcagact cctctacttg tcttcttgaa ttctggaatc agacacacct gggtccagcc 176400 tttgcccccg gggctgtgtg cctgggatgg ttgcctcacc tccctgaagc tcagtgagat 176460 ggggacggct gcacagggcc cggcacagat ggcacccgat ggcacagggt cacctgcttg 176520 catccataca gcctcggccc tcgctctggc tgcgtaccga gagtcccatg cccagacctc 176580 tgctgagtct ccaagctcct ggtcatgcct caggcctccc gtgagaagca tcactgcatg 176640 gaccatgcct cgggacctca ccttgggctg ggaagcttgc tccatctccc caagtctccc 176700 ctagaggcgc cccatgtccc atcactctca ctgcttgagg ggtcagatag gggaacccag 176760 tgtgggaggc ccagaggtgc cggagcagac gttaagcgag ttccgtgttt atgcgctggg 176820 ccttggcaga caccctgaat gagcctcttc cccaggaagg agattggggt cccagtccaa 176880 gttgtggcct caaaccctgt gaccaagagt ggagaaaagg caagacccct cctcccagtc 176940 ttccagaaca gccgatagtg gtggaaacat ggggttcaca ctgaatttcc ttgtaacttg 177000 ttgaagagaa tttagcccac attttcaggg gtggaggtct ggccgatttg gcagtgtgcc 177060 cgtccccctg gccacagttt actctggacc gggcaccctg gtgccctccc tcagtgacgc 177120 agtgaagtca ctatgacgtg tttagttggt gagaaagtgc ctcctgtaat gttttactct 177180 tcttagaggg tgaataagcc ttgtttatta taaataatta tttacagaat acatgaggtt 177240 taacctaact ctgggccacg gcagcgtccc ctgggtaaac ccacgcgcca ccctagctag 177300 agcctgtgcc cccacaggct tcctggactc accctgaagg ggggctggat tttctgcctg 177360 tcccgatgag agggctgcag gacagtcccc agcgagccct tctgagggct gtaacctctt 177420 cccctggtat tttcctgctc gccaggaatg tttcaagctt ccagcagaag cctacccacc 177480 atagtcgctt tccaccctgc tcaccatccc tcctgccctc actcattcag cagaccccgt 177540 gcacagccca gtgcaggact cagggtggga aggtgtcccg ggtgggctgg agcaaggttc 177600 ccagccaggg cggggtccca aggtgggtcc acagccagga ctgtgatttg ggaggcccct 177660 ccctgccttg ttccagcccc ggcaccgccg ctgtccttgt gctcagtgga gactcactgg 177720 ctccaggctc taaaacctca gcgaggtctg cagacaggga ggagccccac tcgagggtag 177780 agtgactgcc gggtccattt gcctgttacg aaccacgtgg cctcagacct gccattcctc 177840 ctctcctaga gctatggtct tttgtctgaa aaatggataa tgatggttac catgtcaggg 177900 accattttga ggacaaacgg ggatgaaact gaagaggctc agcacggaac ctggacacag 177960 aagtgctaat tgtgtgttac cagctgcggt ggctgccaag gcccaaccac atggcagcca 178020 cgggctgagt ggcgggcggg aagtggggag caggagcatg caagatgggc attcctgaag 178080 tttctgatcc agtgagataa gtacacaccc agctctaaga tggagtgtcc caggaaggtg 178140 gagactgcaa aggccttgtg gcgcaggagt gtgagctgca cctctgggct ctctagaatt 178200 tcaccagagc tcagggagga ggtcagctca gatatagggg caacgggaga gatgggagtg 178260 agaaaatggc ttggcgtctg gaagtggagc ctggaaaggt gggcgtgggg acagaggagg 178320 gccttggggg ccatgggccc atgcgtccag gaggtggagg cagtgaacgg ggccacggtc 178380 ggccccacac gtggcaccac cagccctgct gagcctgcac ctgctcctca ggccccctga 178440 gtgccactac cacctggcac cccttggtct gattcctgct tcctgcccgc ctgggaagag 178500 tgagaccact tgcctaaagt cccttagctg tccttaacca ttctggctgc ctcctggccc 178560 tgtccagggt tagccgttga cctgaactgc ctggtgccac ctccccagac tcctggggcc 178620 ttgccctggc accaacagcc acctccatct tcatcattca ctcgcacatt cacccagcag 178680 tgctttttgg gcatccactc agcaatatca aggcgctgag atgcggctgt ggttaagacc 178740 cgggcccggt ctgtgaggac ctcgcagttg ccatttcccc agagcacagc cccagccagg 178800 cacactgtgg ggtccagaaa gagaaactaa tacattgtgt tcgtccattt tgagttgcta 178860 taaggaatag ccgaggctgg ggggttattt gactcacggt tctgcaggct gtacaagtgg 178920 tgccagcatc tgcttggctt ctggggaggc cccaggaagc ttttcctcat ggtagaaggt 178980 gaagggggag ctggcacgtc acatggcgag agagagaact cccagactct tttttttttt 179040 gaaatggagt ctcgctgtgt cagccaggct ggagtgcagt ggcacaatcc tcggctcact 179100 gcaacctcag cctcctgagt agctgggatt acaggcgcat gccaccgcgc ccggctaatt 179160 tttttgtatt tttactagag atggggtttc accatgttgg tcgggctggt cccaaactcc 179220 taaccttgtg atccacccac cttggcctcc caaagtgctg ggattacagg tgtgagccac 179280 ctcacccagc cctcccagac tctatagcaa tcagatctcc cggactttgt gaccgtgggg 179340 agggcaccaa accatccatg agggatccac ccccatgacc caagccccac cccccccagg 179400 ccttacctcc aacatcaggg atcacatttc agcatgagat ttggagggga caacgtccaa 179460 accatatcac acgtgacctc tctgtgcgtg cgtcagtttc tacatctggt taagcagtag 179520 aagctccttc tctgttcctt gttgagagag cggtggggga gaaatgactc agggatggga 179580 ggctggtccc ccgaggggcc ctggtgtttg tggagtggga gtgcgggaag gcccctacgt 179640 tgtgtgtgcc gtgctgggct ggctcctcac agctcaccgt ggtgctcccc gaggactgct 179700 ggggaggaaa gagctaatta acttggggac ccagctgctg aagttatcat taaacttgag 179760 cagtccaggg gcccctctcc ttctgggtcc tatgtcaccc agcacagtgg ggcttaattg 179820 aattttttct catcccccaa ggctcctggc tggcgtggct ggggtttggg atacggggag 179880 cgagagggct tgggcctctt ccagatttgg agtgggttca ccagaaatgg cccaggaaac 179940 cgcgggggcc acccccagca gctgggggct cctgtggtca tttcctcttg gtcctgttga 180000 gcagccctgg cccctggagc cctcagcaag ggatgtgggg gcctgccagg ccagggtcct 180060 cactgctgcc gctatgcaca gctgcatctt gcatccgggg agtggggtgc cgagtggggt 180120 gtttgggagg caggttttcc cttgtccctt ctgcccagag accttgggga tgagttgagt 180180 gagacccttc cggcttctga ctggctgtgt ttctgttgcc atcccccact ccttttaagt 180240 ggaggtttat gacttccttc tttatttaaa agggtcattt agtgacttag cagatcccag 180300 tctgtgttac ccagggccct tttaaaaatc tgtggggagg ctgggcttgg tggctcacac 180360 ctctaatccc agcactttgg gaggctgagg cgggtggatc acctgaagtc aggagttcga 180420 gaccagcctg gccaacatgg agaaacccta cctctagtaa aaatacaaaa aattggctgg 180480 gtgtggtggc acgtgcctgt aatcccagtt actcgggagg ctgaggcagg agaatcactc 180540 aaatccagga ggcggaggtt gcagtgagcc gagatcacac cactgcactc cagcctggac 180600 gacagagtga gactctgtct caaaaaaata aaaataaata aataaaaata aaaatccatg 180660 gggggacctc tgtgtccatt ggctggtgtg aggagagggt gaggagctgc agagaaggta 180720 ccaggctgag gaccgccccc acccttgggc tacagaattg aaggagggga cacatgaaag 180780 atgttcctag actcgggctg gaggctgggg acatccgagg gcaaggacga cgctgtccct 180840 gctcttgttt gcagaggagt gcacagggct caccagcttc ttgttgctgt ttaagtgata 180900 gctttatgga gatagaattc acatactgtg acgttgacct ttttaaaatc tacagttcaa 180960 tggttttgct gtattcacaa agtgattgta ttagggtcat ccagagaaac agaaccaata 181020 gaaggtgtgt acgtgtgttt agataaagag atttattatt atgaggagtt ggctcacctc 181080 attacagagg ttggcaagtg ccaagattgg cagagtaaat cagcaggctg gagacacggg 181140 agagcccatg ttgcggctct ggtgtccacc tgaaggccca agacccagga gagccaatgg 181200 cgtcgttcca gtcccgagac ccaggaaaag cgcatgtgtc agtttgagtc tgaagcagga 181260 aaaatctgat gttccaggtt gaaggcggtt aagcgggaag aattctctct cactcaggcc 181320 ttgtgtcctc ctattcagac cttcaggcct ttgtcacaaa attacaaaga cctgatcaga 181380 acaaaatctg agaaaaaacc ctttccttct atcggttttg gattcattgg ctgggaccct 181440 ggaaattaga ctgacagaga ttaacaggaa acaagcataa caattcaagt aagttttact 181500 tgacaccgag ccttcataag gaaatgaaga cccagagaaa ccgttagcct gagcggtttt 181560 tgttttgttt tgagacaaag tctcactctg tcgcacgtcc aggctggaga gcagtggccc 181620 gatcacggct cactgcagcc ttgacttcct gggctcaagc tggggcccag ctgccggccc 181680 cgggagctgc tctgaaccca ctcttaagtc ccagctcaga ctcccaagta gctgggacta 181740 caggcatgtg ccaccccgcc tggctaattt tttatttttt gtagagacag ggtcccacta 181800 tgttgcccgg gctggtctca aactcctggg ctcgagcaat cctcctgcct tggcctccca 181860 aagtgctggg gttacaggtg tgagccactg tgcccggcct aggcctgaac agtttttatt 181920 tgttttgctt gttttttaaa tttgtttgtt gcttgttttg agcagttttt ttgtttattt 181980 cttttgcttg tcttttgccc aggctggagt gcagtggcat gatctctgct cactgcaacc 182040 tctgtctcct gggttcaagc cattctcatg cctcagcctc ccaagtagct gcgactacag 182100 gcgtgtgcca ccacacccgg ctgatttttg tatttttagt agggatgggg ttttaccatg 182160 ttggccaggc tgttcttcaa ctcctgacct caagtgatct ggccaccttg gccttccaaa 182220 gtgctgggat tgtaggtgtg agctgctgtg cctagcctag gcctgagcgt ttttatgctg 182280 ggtttgatga agagtggaaa gtcgtgggaa actgtgacag agcaacaaaa gatgagctga 182340 acagtgagcc cgtgggggtc tcggcaagac ctgtgtactg gggcccctct cagatcctct 182400 gtctctggag atgaggctgt tcctttccgc tgggtgtagg gagggcacct cttacgtgag 182460 gggcttatga tctacttcag agaaggggca ggtcagtgag ttcttcttgg acctgccatt 182520 tcttaaattc cttcagctga aaatatttac tatgccaagg cactgtatct tggagtgtgc 182580 gttccaagcc ctgttgcctt caactgatcg ggtgaggccc acccccatca gagcacacag 182640 tctgctttac ccaggctcct gattgcaccc ttttcctgtt tgccccgaga atactcacca 182700 gcagtgcttg tggctgcagc gttcacccca agataaattt gccgggaagt atcttgcttt 182760 tattattatt ttcacatcac tctagtatat cgactttgga aacaaaagac atcattctgt 182820 ttatagcatt ccatttttag tagtggtatt tcctttaaaa aaaaatggta attctcagct 182880 gggtgtggtg gctcatgcct gtaatcctag cacttgggaa agctgaggca ggctgatcac 182940 ctgaggccag gagttggaga ccagcctggc caacatggtg aaatcccatc tctactaaaa 183000 atacaaaaat tagccaggcg tggtggtagg cacctgtaat cccagctact tgggaggccg 183060 aggccggaga attgcttgaa cccgggaggc agaggttgca gtgagccgag atcgcgccat 183120 tgcattccag cctggacgac agagcaagat tccatctcaa aaaataaata aataaataaa 183180 atttaaaaaa aaatagtaat tctcgatcgc tgaaaatgtc aaatcctaga gaacacagca 183240 ttcctacaag tgatgttaac attgttcttg atcagttgtt ggctgaagat tcatttgatg 183300 aatctgattt ttccagaata gacgactcag atgactctgt tgttttgctt agaaataact 183360 gcaggaacaa tttaaaaaat tttttttctt tttaattttt ttgttttttg agacggactc 183420 tctctgttgc ccaggctgga gtgcagtggc acgatctcgg cttactgcaa cctctgcctc 183480 ctgggttcaa gtgattctcc agtcttagcc tcctgagttt agctgggatt acaaggtgcc 183540 tgccaccaca cgtggctaat tttttgtatt tttagtagag acggtgtttc accaggttga 183600 ccaggctagt ctcgaacccc tgacctcaaa taattggccc atgtcggctt cccaaagcgc 183660 tgggattaca ggcgtgagcc accacgcctg gccagttttt atatttaatt ttcacacaga 183720 gcatccagtc agatttgctt cagcctcaaa gagcgtgttt atgtaaaatt aagtgagtgc 183780 tggcagtgag ctgaactttc taaaaggtaa aagggttaaa tattaaactc atccaaaaac 183840 accttcacag acacactcag aataatgttt gaccggttac ctaggtgccc catagcccag 183900 tccagttgac acagaaattt tttttttttt ttttgagacg gagtctcgct ctgtcgccca 183960 ggctggagtg cagtggcgcg atcttggctc actgcaagct tcgcctccca ggttcacgcc 184020 attctcctgc ctcagcctcc cgagtagctg ggactacagg tgcccaccac cacacccggc 184080 taattttttt ttttgtattt ttagtagaga tggggtttca ccgtggtctc aatctcctga 184140 cctcgtgatc cacccgcctc agcctcccaa agtgctggga ttacaggcat gagccactgc 184200 gcccggctga cacaggaaat taaccatcac agttacacag ccatcgccat taatcccagc 184260 acatttcatc atccccaaaa gagaccctgc ccccattagc caatccccat tcccaactcc 184320 gggctctcag cccctagcca ccgctcatct gccttcgtct ctatgaattc acctgttcta 184380 gatagtttgt ataagtggaa tcgtacagta tgtggccttg gtgtctggct cctttcactt 184440 ggtagaatat tttcaaggct catccacatt gtagcaggtg ctggtgcttc attctttttc 184500 atggccgaat aatattccat cgtggataga ccacactgtg tatctcttca tctgctgatg 184560 gacatttggg ttgtttctgc tttttggcat aattctgttg tgaagaattc tgcagtgagt 184620 gctggtctac aggtttttgt gtgaacatgt tttcatttct cttgggtaat tgcaagatca 184680 tgtggtttag ccaaccagcc tttaagccat gtgtctgctg agggacccag gcctggtggg 184740 ggtgcattgc tgtgcttggc cagccaggtg ctgcgagtcc gtgtcgcagc catttctctg 184800 tgctgtgctc tgaggttgtc tcgccggcac cgggcactgt gagccccagg aggccaaagc 184860 cccctttgtt ttatcttgag tccaggcctc gctccatgaa ctaggatgaa tggacattga 184920 atcaacgcag ggatgggtgg ggctggggtg gggacgcaga gtgaccccgg gggcctgcag 184980 ctgggtcctg gctgctgact tccagtttcc tttgcctgtt ggagcccaga acaagtcaga 185040 aaggggaaat gcaaagttcg agtgtctttt ctgtggtaga ctggcaggcc tgggtgggtg 185100 agccacttgc agctagttgc agcgtgagag aggaagtggg aggggaggga gagggtgagt 185160 ttggtgtaac tcacccctgg aaggaggctg ggctgaggct gggggaagtg acttttattt 185220 ttctgagagg attcttccct ggggccaact tcaaaccaag ggagacaaga ccttcctggg 185280 ggaggctgga agtgctgggg cccccaggtg ggcaggtctc ccagggccaa cgtcttgggg 185340 aagctataag ttaccatgtt tctggactgt cacacacaca cacacacaca cacacacaca 185400 cacacacaca cacacacaca cacgagtaaa ctgtaacaca aatgtgtgcc catgaaagtg 185460 cccactttaa accaccacac agcctgtaaa gcgaaggccc tggcccgcat ctgggcaccc 185520 actgcccagc cagccggtag gcagtttgca ctgtagtctg ttaccatccc tcagagatgc 185580 agccgaggag cccagctggc ttggagggcc cagtgggcgc agcctcagga aagtggtcag 185640 gcccgggcca ggccccttcc ccctcccagc cttgggagaa attaccatat gaatgtagct 185700 ccttcccgga gttcgggctg gaagggcctg ggaggggaca ggctcccacc ccaggagctt 185760 ccaggttccg gctgctgcct gtgttagctg cgtgagcgtg agcgagccag gggtcactac 185820 tgggtggaag gaagaagcgg gcatttcttc caggaggtca ccgttggagt cccacagtag 185880 gtcaacccca ggccctgggt cctcgggagg aggagaaaga agagaagcag gaggtgtgga 185940 gggtaggcca ggaccagaag gcacacaggg tcggggcagt gtgggagacc ctgggggctc 186000 cctcatttaa ccagctaaca tcacagcgtt cataagaaca cgctattact gcagttttat 186060 tactttgctc tgatttcaga aggcacaact gatgacttta gggaacggag aatctgagga 186120 aggcctcgca ggagagggtc agatgcgatc gagtaaatgt gagccgtctg taaactgtag 186180 agtgcacgca cagcaccggt cagccctggg gtcagtgttc ccctggtgct cagctcggcc 186240 tctgcacctt ttagtgctcg gctgggctct gtgggggtca gggctgggtc tggtacatta 186300 gaggacttct accaagcccc tggcagtgtc tcagttacta aatccagttt gccagttact 186360 aaatccgctc tgccggttcc cgaatcactc ttccgctggg gccggccatg tcacgtcagg 186420 cttttcatgc aggacggcag atggatagac gctgggacca agtcatcctt gggccgcgag 186480 acgtctgacc ttctgctggt gtctcagaag atgctagctc tccgtggcat gtcttccacg 186540 cggtgcttgg ggaccagtgg cctctaaggg gcccccctgc ctcagcgtgg ggagtggcct 186600 ggccaaggtc tcagtgtctg gttggagcca ggcataggct caggtgtact ggctggaggc 186660 ctcctgccca tgggctctgc ctgtcctgtg tccctggtcc ttactgtgtc ttctgtgttc 186720 ctgggagaga ccccaggggc cctgagccca gcactggggt tggggagtgg gcggggaaga 186780 gggtggggat tagggtccct ggctgcagaa cagccaggcc ccaagtcccc actccactcc 186840 cctcccaccg ggcgcctcat cccacactga ccatttcctg aagaaaattt cctgaaccgg 186900 cctcccaccc cggctgtccc aggaagccca tccatccttc cgccttaatg ctttgtggct 186960 ccagaaggat ggtggaagcc ggaaatcatg agtctcattc acaggcggcc acacaccgaa 187020 gccgcggaga cgccgtggga aaggactctg gccagcgcgg ccggcacaga gggagcggtg 187080 ttaccggggt agacgggaac cgtggctgcc cccatgctgg tctgggagag acgaggggcc 187140 ggacgaaagg acagcagact ggccattcat tcatttattc attcactcat tcacagcgtc 187200 ttactgggtg cttcggacgt gtaaggtttt gtgggtagtg aatgcgacag accccagaca 187260 gcaatcggag ggccacgtgt gtaagaactg agggacctag gctgggcgtg gtgtctcaag 187320 cctgtaatct cagcactttg ggaggcagag gcgggcggat tacgaggtca ggagatcgag 187380 accatcctgg ctaacacggt gaaaccccgt ttctactaaa aatataaaaa attagccggg 187440 cgtggtggcg ggcgcctgta atcccagcta ctcaggaggc tgaggcagga gaatggcgtg 187500 aacccgggag gcagagcttg cagtgagccc agatagtgcc actgcactcc agcctgggcg 187560 acagagtgag actccatctc aaaaaaaaca aaacaaaaca aaacaaaaca aaaactgagg 187620 aacccagtgt agatgagcta tcccgggaaa acaagtggga gttctaggaa cagcatgggg 187680 aagggatggt cccggcaggg aggacctctg tgggtagcct tgttggaaga gctgaaaggc 187740 agccagagag gctgtgcgtg gatggaagct gaagagtagg ttaggggcgt gtgttttgtt 187800 aacaaagact tcaagcattt actgaccagg cacaacacta tgtgcttcat aaataaatat 187860 ctcatttgat ccccagcatt cttatgagac agatgttatt atcccatttc acatgtaaga 187920 acattgaggc acagagtggt taagttactt gctcagggtc acacagcacg tcggtggtag 187980 gcaggattct ggagccacag gaatctggta tatcccaggt gcaatggaaa ccagtcacgg 188040 cttcatagag ggaaatcatc agattagtaa attttacaca cgccccctgg tgctttgagg 188100 aggagggatt cggacagggg cagctaatgg tggtggctgt gagatgtgtt gggttaacat 188160 tgatgagagt ttgggatgga tgagtggatt cggagtaatg gaaatggagg gcccaggccc 188220 ggcccctgga gatctagctg caatagctgt tggctggaga ggctgttcac ttagatgggg 188280 gatggggtgg gaggcaggtg agatgagagc tccagagttc agcctggggc acggtcattg 188340 ggttcaagat gccttcagat gttggggctt gacagtgaca gtggctgcag atacccagga 188400 cccagcagag ggcctggcac agcggggccc agggacacgt ctgtgagtca ggctggcact 188460 caagtgtgaa tctggacaaa gaaggtggca ttgttggcat tgaatgctca ggggctgggt 188520 gaagtcagct agggagaggg gctctcaagg caccaggact gactccgtgg gtgagggcgg 188580 aggaggagac ggcagaggct gagagaatag ccagagacag gaggaaggtc agcagagcca 188640 tgcacagaag cctggagaag atttgaggaa aggaagggct gggtggtcgt cattccctgc 188700 agctaggagg caagggtgac ccctgtgtgt ttcattcttc agaggattgg tggctccatc 188760 tggtcagaac cccaagtcca gagatgcatc tgagcttcat gccatggtgc aggcagcagg 188820 agccatggag caggcctgcg gggtcacggc ctgcctgctg cttcctggtg tctctaccct 188880 gagctcaggg gttgcttgga tgccctgtgc tgcatccccc caggcggtgt tccagagagg 188940 atgaaagtgg ctatctcaag gtgtgaccag gtagcggtcc atgcacactg ctttttcctg 189000 gggagagtct gggatggaag ggtatgtgtg tgtttctgag actccttgaa taggctccat 189060 gtacctatcc acccatctta ccacccaccc acccatccac tcactcaccc atccacgcac 189120 ccacccatcc acccatccac tcatccacct gtcaacccat ctatccactc attcacccat 189180 ccactcatcc acctatctac agtcattcac tcatccaccc atccactcat ttacccatct 189240 atccatccac tcatccacct gcccatccac tcacccaccc atccactcat ccacccatcc 189300 acccatctat ctatgcactc atccacccat ccactcatcc acctatccac tcattcactc 189360 attcactcat ccacccatcc actcattcac ccatctatcc atccactcat ccacccatcc 189420 actcattcac tcatctgtcc atccactcat ctacccatcc actcattcac ccatttatcc 189480 atccactcaa ccatccactc atccacccat ccactcatca tccgtccact cacccatcta 189540 tccacccatg tatccatcca ctcatccacc catccactca tctgtccatc cacttatcca 189600 cccatctact cacccaccca tccactcacc catccatcta cccatcctct catctatcca 189660 tccactcatc tacccatcca cttatccatc catccactca tccgtccatc cactcatcca 189720 cgcatccact cacccatcca tctacccatc cactcatcca cccatccact tgtctactca 189780 tccactcacc cacccatcca ctcatccacc cattcactca tctactcatc cactcatcca 189840 tctatccact catccaccaa ttcactcatc cacctatcta ctcatccacc catccatcca 189900 gtcattcatc catttgctca ttcatccgcc aacccatcca ttcacctgcc tgttcatcca 189960 cctacccatc cattcatcca tctgtccatc catccaccca cccactcacc cattcacaca 190020 cccatacacc catccattta tccaaccatc catccccatc cttacttcag aaagcatttg 190080 aagttgctgg ggtgtgcact tggaaaatgc gtcataagct ttcataggcc tctctttggc 190140 ttcctcactt ctttgattgg tctttctttc ggacatgcag gattctgagc agctcttctg 190200 ggaggtgggt gcagtccagg taggctgcct gcaaagctag gaccgaggga gccacatcca 190260 aggcactgtg ggttcccaag gcgatggcac tgtgggccca ctgcttccag acctcctcaa 190320 ctcccaggct cctgagcagg aggactcctg gggcagggcc tggagacggg aagagaaaac 190380 aattccagtc tctcaactct tgtcagtcca ggtgggtgct gcatggattg ggggcacctg 190440 gaacagttgg ccccttcacc cctttccccc acctttccag cccctctggc tataatcaga 190500 cagttgtgtg cgatgtcttt ctccctcctg aaggggtcat ttagtcaggc tcctactcat 190560 ggcccaggaa tgtgcccctc cctgcctgtc ccctaccccc aagcaggccg tgcctccagc 190620 cccctgctgt ctctgaaggg cctgggcatg gggcagcctc tgcagcatcc ccagggcccg 190680 agctgatctg cacagcagaa gggaattggg ggaaagcttt ttttctaccc agcacctggc 190740 agggggccac cctgttgcac cccagagacc cttgtctaag ttttgttatt tcagatgatt 190800 tcataagttg ggggaggcgg agccccagcc cccacagccc ctgttgttgc ctcactgctg 190860 agctctgctg tgtatctgct gacaggtctg ctgatagcag aaggggctgg agagagggaa 190920 gctctgggcc ctgccctccc caacccctgc ttaggggaca tccctgataa gaggaaattc 190980 cagcctgtga cagatggcca gtgtccaccc acccacgggg gaacttttct ttctctttgt 191040 aagtttgcag atttgccagg aactaaagga atctctggtt gacaggccac tgtggacatg 191100 gctggagggc tggcacgggc tggatcttgg ggttgctttg aggtaggggc cgctcctgct 191160 ggaaggttcc ttggggtggg gaaggcatca gggccattcc ctgaccctcc ctctgcagtg 191220 gatccacttc agagcctgag acaaggcaag ggggcagcag aaaacagaat ataaaatagc 191280 cccccccacc acacaccgca ccagaagtca gaggattcat ccttggcctg ccctccctgc 191340 agcctaagtt ctgagagtgg ctctttagga agtgaatggt gatggtttgc aggtcagagc 191400 ttgctctggc ccaagattga tgtctcaata ggccgcggag cctgggtgaa aaaactcagg 191460 ctagggaggt ggtgggttgc aaatgaaaga acagaggagg gcctcttcca gaaagcggcg 191520 ggtggtgtga ggagcccttg gaccttgtcc aaatttgact ttaccgactg gggccaattg 191580 aaaccgtgct ggcagaaagg caaaactgct tgagattcct tcctccacaa tagaggagag 191640 gtttgcttga aagggtttgg cgagggaaaa gctggaggaa ccttggccgg cagtaaaagt 191700 ggggaccccc gccccctgcc tcgggggcgc ctcggcccct gaatgaatga aagaggaggc 191760 tggatggaga cagactcaca ccacctgtcc cttccaggtc ctgcaaagga gcacacaggg 191820 ttcttgttgg ctcttccacc ttgttagtca ccaagaagga gaaaacacca acaggggaac 191880 tgtaaagctg cagttttgtt taagccccat agtggaaacc ggaaagagct ccagctcgga 191940 gaaaaatgca gctctttgcc tttgcaaatc cgtgtctttc tctgggaggc cagagccatt 192000 gtgctcgatt tctaagcagg gtttcagagt gtctcaggag gggaaggcag agtctcagat 192060 ttccggcatc ccaggtccta accaggcttt gaggagacgc ttcctgtccc atacaaagtg 192120 tgaagtgtaa tttgatttgg agttagttaa caaattagat gagctgtgtg cattttaaaa 192180 attcagtcct tgatccccca cccacacaca tttgcacaat ttggtcattt atattcagtg 192240 tttccatctt tagaagagaa caggaagtcc ccagtgacat ttatggagtg tttgtagtag 192300 cttgggtagg tcagtaggaa cacaatgcag tgaaaagcag agttgagatg ggaaaatatc 192360 ctgttttcag agccccccag ggatgacatt ccttatcgtc tctgtccacc cgctctggag 192420 tccactccgc aaacagcaac ttgttctcac ttgagagctt cctcctgccg gagctcaggg 192480 atggagagca gctggcctca gtcttctcct cttacctctt tgtttctcag actcatcttc 192540 caccttgaat aattgttttt aacctgctct ccctcttctc tagctgtaga acccagaact 192600 ttgtgtgtgt ggtcaaaagt ttagagagtg ctgcaggtaa tgctgagata accctattaa 192660 attctgtaag ttctcatcac accaagtttg tttgtttttt ttaattctca ttttatttta 192720 tttcatttta tagggatggg gtctcgctac gttgcccagg ctggtcttga actcctgggc 192780 tcaaacgatc ctcccgcctc ggcctcccag agtgccaagt tattttttta actgggatcc 192840 acgggcctag ggattctttg atgaaccgtt caaaatacgt gtgtgtctgt ctgtctgtct 192900 tcaatgtata cttttctagg gagagtcttt acttttcacc agaggtttgt ggcacacaca 192960 tgtcctgtac tactgtatca gattgtgaat tccttacatg ttaaagactg cttcaaatct 193020 gtccggaagt ctcggctaat aaacatttaa ataaatgaac ttcaaattcc catgtgccac 193080 cactgttttc attctgacta ctctcaagcc tgtagtgtca tctttttgtt actgtgaagt 193140 agacactcaa taaatacttg tcaaatgaat caatgttatg gtcctggtcc actaggaccc 193200 caggatcatc gtctaccatt attgtctata gtttctttac catcttgttc cagagcagtt 193260 ctttctctga ggtctgctca cctctgcacg tgtgtctagt ttccagccct gtcgccttac 193320 cattctcttt cctttacctg catttcctga actgttaata gttaacaata gcttctccct 193380 ccacccactc actcatacct gaagtgagaa gtcatcattg aggtctctgt ggattttgtc 193440 agcccaacct ggggcggcct cctggaggtg gagttttcag atgagggatg gacattttgg 193500 tgtctgctgg gtagatctac ctgggagctt tggcaggggc cccagggcag ctctgcctct 193560 ttattttggc tgtgggaccc ctggtgcact agggtttctc aagtaagcat ctgtgtcctg 193620 ggagagccat aggcaggcct gagagggccc ctggaatctg ggacccccag cccggcccag 193680 tagctggtac catcatcttt cttgcaaggg aagttatgga aactaagatg ctaatgtgct 193740 ttgataggcc tggggtggct ctaagccctg ggaagagccc tggcaacttt ccctggctgg 193800 cgggtagaat cttctcctgg cagttcaggg ctctgcctcc agctccctgg gggagagcaa 193860 ctgagggagg agctggaggc caaggcctca gtgctgagct gcctgcaccg cagctgcacc 193920 ttctgggtcc tggctgcagg aaccccatac ttctccagcc tttccatggt tcccgaagac 193980 ctggcctggg gagggggtca gcagcctggg gctcacctac ctggcttcaa atcctggctc 194040 taccgcttac tcgctttgcg accctcataa ttgacaaaag ccctctcggt ctcggtttcc 194100 ttatctgtga aatgggacaa taacagtggc taccttatag gattgtgtga tgatccatca 194160 gttataatag ctcctgagca gcgtttagag taacacctgg ggctcggtgc agtggcttat 194220 gtctataatc ccagcacttt gggaggccaa ggtgggagga tcgcttgagg ccaggagttt 194280 gaaaccagcc tgaccaacat tagtgagacc cactctctaa aaaaaaaaat tagagtaacg 194340 cctggcacag agagccccca gtaaacctcg gctgctgtga tgagctttgt ttcttcattt 194400 gttcattcat tcaccagact ttttgccggg gcttgccgtg agccctacgc tgctctgaag 194460 aaagccgggc tggggtgagc gtgatggatg aggtgtctgg cttcacaaac cctgtgtggg 194520 ggggttgtgg tgagaggaaa ccgcacacat cattattcag ttaccatcgt ggggagactg 194580 tctggacgca gagagcaggc tctgtgtggg agcggggagg gcaagccctg gttgcgaggc 194640 agggcttccc caggattcag cagggatctg aaggactttg caggcaccca gggagatagg 194700 agaggaggag ggagcagccc tggccggaca ctgtcctcct agcattgcct gcatcaggga 194760 ctcactcagc tttaagaagc ccctttgtgg gggacaggga gcatctgtta gtttatagga 194820 cctgaagtgc ccccatgggc tcaagtttct gggaaggcct gcaggtggcc gtagggctgc 194880 cgcaggggtg ctggccccag ggtctggatt caggggagcc tgcagaggga gggcagctgg 194940 aggctgctcc agtgtgcatt gttacgaggc aaagtaagga gactgctggg cccacgctgg 195000 gccggggtgg atggaggcaa ggaagtcttc gccggggcaa gggcaccagc tgtagatgcc 195060 ggcagctttc tcctggacac gggcctggaa ggctgacagg gtgtggtgag tgccaccggc 195120 tcccctgccg tggcctggtc agtggcttca caggcctccg tgggcaggag gaggatgacc 195180 ttgcattctg cttggccacc attggcagtg acagacaagg tgtgtgggga tgtggccatt 195240 tcggtccgtg ctctgagagc caggtgtggg ttgggtttgg ggaagacagg ggaatggcat 195300 tgacttgacc ctgagcactt tgtcctgggg tgcaggcccg gctgtcactc ccctggagct 195360 gggaatggca ttgggcggtg gctcagggtc ccttgcccca gcggcaccat ctctgcattt 195420 ggccagcaag gctgatggga cttgtgtgga catttctggg acgtagacca ggcagcatga 195480 cacacaggga ggggtaggca gagaagggcg gcccctgggt cttggtttcc aagtcaggct 195540 ttgcaagcct gctgtgtcaa gccctctctc ggcaccaggc caggtgggcc agggtcagcc 195600 ctggggctgt gatgagtgtg agtgccccta aagtgtgtca tgtccaatag ctgcctcctc 195660 tctgggcact gcctcccagc cagatatcct acagcccccg tcccagccac agacagcaat 195720 ctgattccct catcctcggc aggtcctggg gttggggtaa gaatttgtca ctaagtgcag 195780 atgttcccag agggtgctgg ctcagggctg cgtggattac agccctttca tccctgcctt 195840 agacccacct gcaactctgg agaaaagatg gcccagtgga cgcctgcggg gaggagggag 195900 ctggtcccca ggatgagcag atttgggggc agtccccatc acgggaccgg tgacctactg 195960 ccaccagcgc cagtgaatgg cagaggggcc ctggcataag gcctgggttc agaatgggaa 196020 cctgcagaga aactgtcaag gtctcccgcc acctgacacc tccgcctggc tgccacccta 196080 gaaacaccct tgctgcaaga agatggggga gtttgtctgg ggcatggtct ggcgacacca 196140 acttgagaac ctcaggccta agtgttggcc tctgggcctc agctgtcctc tgagctgtaa 196200 agctggctcc tgggcacttg tggaaaacac tggactcttt attttatttt actttacatt 196260 ctgggataca tgtgcagaac gtgcaggttt gttacatagg aatacaagtg ccatagtggt 196320 ttgctgcacc cattggactc ttcaatccag ctccactaga aatgactgcc ttctttccct 196380 tcttccgtcc ctccctcctc ccctcccttt tttccttcct tccctgtttc cttccccctc 196440 cctccttccc ttctttccct tcctctcccg tcctcatggg gatataattt ccatattaca 196500 ccatccgccg attcagaaag cacagttgag tggcattttt tcacaacctt ctataagcat 196560 cacctctaat tccagaacgt tttcctcacc ccaaaaggaa acgccatcct cggtacacag 196620 tcactccccc tcccccagcc cctggaaatc accaatctgc gctttgtccc tacagatgta 196680 cttattctga acatatgact agaaccctaa aagatgtgac tttttgtgct tggtttcttg 196740 cagttggaat gttttcagag ttcatctgtg ttggcgcacg ctcgtgcctt tttatggctg 196800 agaaatagtc cgctgtgttg actcagcacg ttgggtttct ccacgcatct gttggcggat 196860 gtgttagtta tttctggagc cgggtgtgtt gtgctactca cgggctgcac taggagctgg 196920 ggatatcact gagtaagcca cagcctcggg cacccaggag ctcgcagagc aggagctggg 196980 agggaggtca ggaggtgcat ggcctgtttg ccaggctgga gagacttgca aaaagtcact 197040 ttgagccaga aaccagagcc tgaggcctct gactcccagc tgcggagccg ggagggaagc 197100 tctgcatttt gctttgactg tggggtgacg tgtcagttac tgtccaaatc agaacctttc 197160 tgagagtcga cgtgggtact gctgataatt agtctggata cccgaaagaa tggaaagcag 197220 ggacccagac agatccttgc acaaccgtgt tcgtagcagg gcgaggcctg gaggtgcgat 197280 ggggatctca acggggcagc tgccgtcttg ctggagccca cggtctttgg ggggggtcac 197340 aggtgttaac cgcatatcat acaagcagga gtgtgaaatt tcagggttgc caaattcagt 197400 gagggtcttg tgctggcctg gccacttaca gtggcatttc aggaaaaaaa atcactctat 197460 ggacctcagt ttccccatta gtaaagagta ggttggactg gaattctgta ccatccagta 197520 tagttgccat ttatgaaatg tggctattta aatttaaata aaaatagaaa ttccgttcct 197580 cagttggact agctcagtgt caagtgctca gaagtcactt gtgaacacac tgtggcaatt 197640 cctcaaaaaa cgaaaactag aaccaccgta gcatcccata attccacttc tgggtgtgga 197700 ttcaaaagaa tgcacagcat cttaaagagc tagagatatt tgtacaccca cattcatagc 197760 ggctctgttc acagtagcca gcgggtagaa acaacccgaa tgcccgcggt caaatgaatg 197820 gagaaatcaa aggcgggaca ggccgggcgt ggtggctcac gcctgtaatc tcagcacttt 197880 gggaggccga ggcgggtgga tcatctgagg tcacaagttc aagaccagcc tgaccagcat 197940 ggagaaaccc cgtctctact aaaacaaaat tagccgggca tggtggcggg tgcctgtaat 198000 cccagctact tgagaggctg aggcaggaga attgcttgaa cctggggagg cagaggtttc 198060 ggtgagccga gatcgcgcca ttgcactcca gcctgggcaa caagagcaaa actctgtcta 198120 aaaaaaaaaa aaaaaagggt ggaacataca aggaatttga ctcagccgta aagaggaagt 198180 taggatacct gcaacagcaa gggtgaacct ttcgggtatt acgctaagtg aaataatttg 198240 gtcacaaaag gacaatcctg taggattcca cttataccag gtccgtagag tagtcagatt 198300 cagaaaaaca gcagaatgga ggttgccaga ggcttggggg atggggctgg ggagttgttt 198360 aatgaggaca gtttgtttta caagatgaaa aagttctgga gatttgttac acaacaatgc 198420 gaatgtactt aacaccactg gactgcacac ttcaaaatag tgaccgtggc aaacgttatg 198480 acaattaaaa ggaaaagtca cgtggccagt ggctaccacg ctgagcagcg caggcctcgg 198540 acggtgtcgt ggtcacagac aatggagtgg gtgatcttta ccattgtttc cagctgtctg 198600 agcaccatgg tgtcctgggg ccaggatgaa agtgtctctg ggtatggggg tctctgcttt 198660 tcccacttgg gagtcctgaa ggcagacccc aaagctcacc tggccaggta ggagagcgag 198720 gcgggctctt gcattgctct ctgcgtgcgt gcctgcctgc gggccagccg gggcctgcaa 198780 ggccgcctct cgagggaggg gttgcaggaa tggctctcac ctgtgcagaa ggcaagccac 198840 tgccctacgt caatggcaaa gatggggctc ggctgcgttg tattattatt tctcaagcgg 198900 ggcccctggt gggcaggatg tttggtttga tttgagtttc tgcagtgagt gctggtgcct 198960 gtggagggac ccagctgcag ctgagccggc ccctccctcg ctctgggctc caggggcgtt 199020 gggggcgaga aaggagagtt cagggggcag cgcctccccc caggtcctgc tggggagggt 199080 tgagggatgc tggggggagg tgggggcggg taggggctgg tcccagtccc aggcaaaatg 199140 gctctcagac ccacaggcag atggaagcga ttttcggtca cgtgggtggg gactgaactg 199200 ctgccccgca aggcaaggcc ccatgtctgg cttcaggaag cggccccaaa gccacatggt 199260 ccatggccag atgcagggct gtgtctttgt ttatttaaag gtcctggaag cccaggggag 199320 agtatttctg aagggggagc aggagcagga gcaaagccct gaaggcttcc aggctgcgtg 199380 gcctgggtgg gggccacgtg ggggcacaga gagaggagcc ctggcctcca ggtccgcctg 199440 tgggtattgc tctcagcagt ggagatgtgt ggaccccccc ttggcatttc ccaacaagga 199500 attatattgt tcctttgttc ccccaattcc ataagatagg aattcctgtg ccctgtggag 199560 gctgagaaga cggggaggtg cctgtgagga taaaccagcc cccagtttct ggcttccaga 199620 gtcttttcct ctctcacctc tgatgcctca ggcctgggga gcctccctcc gacaccctct 199680 gaccgctcca gtgaaatagg ccgagaggga tggcttgaat cggctgggga tgcaggctgc 199740 agccaggggg ctcagtgggc atttcctgag ttcggttctt gccccgcaag tggaagggca 199800 gttgaactga agtctcccac tgcccctcct ggcctggaag cctgcctccc accttctggg 199860 cagagtgagg agtgggcgtg ggccgggagg gctgcctcct gtctgggagg gctgctcact 199920 tgcctgtcac gggggatgag ccccctgcag cctcccgtgc tgtggccctg gctcccacgc 199980 cggctccact cccctgtggc tgcccctgct gggtgcccac cggtcccagg gaaaagccac 200040 tcccctcccg gaggactggc gggaggggcc ctgcctggga gcgtgccgtg tggtccctgt 200100 cttagcgcag gatgcctgag gccagatcct ccctgggagg caggatgggg caaaagtctc 200160 cccgcaggca gagcagggcc tggatgggcc caagcaggga cgggggcaca gaacagcagc 200220 cgcccagcct gcgtgggagc tgagggccac caagggcagc tccagcctgt ggggactagc 200280 agaggcacca cctctgtgac cagcgagttg tctgcacctg catgcgcatg caccagtgag 200340 tgtggcgagt ctgaggtgtg ctgggacctg gcccgtgtac cagccagccc tgatgggaac 200400 cagccccatc ctgggtaccc ctggaacccc actgtgtggg agcacctggg tcctcagcag 200460 gcgtcttccg ggcgtccgcc cccagcccca ggcctctgac ccgtgtgtgg tgtcttaaca 200520 gcagccagga gcagggccat cgaagggacc tacagacaga agaggcttta gtgatttcgg 200580 gaagttcagc tccacgtgcc ccacataccc aagagtaaaa cttggtcttg gcctgtgggt 200640 gtgcagcccg tgggcgctgg ccaggcacac aagacggccg cctgggtcag tccaggggga 200700 ggcagatgtg gtgcaggggc ccccctcctc catgagccca ggaacagctc tgcatccagg 200760 cacccgccct gcacccagca cttttccttc tcccaggact gctggctcgt tctatgggat 200820 tgaacacaca actccatggg gaccgacgct ggttctatcc ccctttctta caagaccatc 200880 catggggatg tgggaggcgg ggacacacgc tggttctatc cccgtttctt acaagaccat 200940 ccctcctgtg tcttggctcg tggatcggct tctaaggcct ttgagtggca gcaggcggta 201000 cagcttatct gagtagaggt gaaggagagg gccaggtcca cctgggtggc ccgaggcagt 201060 gtggagggcc aggagaggag agcaccctcc acccttgtct gagcagccct ccagggtacg 201120 gagacaggag ttcagggtca gccctgcctt ggagcgcagg gggcccccag cttggcacag 201180 ctcctagaag aggagatgaa aaagcctggc cttgggagtc tggggatgga gctttgctgg 201240 ggaggcagcg tggctgcagg atggcagctt tttagaggac accacggcca gggacatcca 201300 cccgggggaa ttctcagggg tcgcctgggc aagtcgctta gcctttctga gcctcagtgc 201360 ctcagtttcc ccatccaagg atgggtgtga caaccacctg gcaggcgcct gtgtgtgagc 201420 ccctgttccg ctctaactcc tctgctgttc cttccccagc cactgaggcg gctcccagct 201480 gcgttggcga catggccgac acccccagag atgccgggct caagcaggcg cctgcatcac 201540 ggaacgagaa ggccccggtg gacttcggct acgtggggat tgactccatc ctggagcaga 201600 tgcgccggaa ggccatgaag cagggcttcg agttcaacat catggtggtc ggtgagtcct 201660 caccttgcat gccactcaac caatgccgga aaccagcctc agcccccagg gcggcccaca 201720 agcctttggg cttggtcttc ccttctgtaa aatggggcag caaccctgac ctcaaggacg 201780 gattgccagt gacattgcgt gtgcatgcat gcgcctggga ggagcccaca gcctccagcg 201840 gctcctcaga ggggcctgtc ctgcacatcc agggcccctg agatgacttt ggggagccca 201900 ggccggcctg gagcaggtcc tgatgagtgg tcgctgcctc tgagcaatga cgtcagcttg 201960 tgcagagggt tctgtggcag ctgtcccctc actgttgctc cagcctggcc ctccaggctc 202020 cccaccgcac cccaccgcac cccggccaga ggcttcccag cagctcagct tcagctctgc 202080 cctggaattg gggcctcgtg gcttccacac cccctggtgg ccccggagag ctggaggtca 202140 ccacgggagg tcgtcgatca gcacgacctg ggcagggtga gggggccagg ctggagtcta 202200 cagtgggccg cctgttgttt ccaaagcccc ccaggtccca ttcaaacctc acagggaccc 202260 tgtgaagggg gcgtcccgtt ttccaggcag aagcgaggct cagggaaggc tgccaaggtt 202320 ccttagctca cagggcagag aaccgcagcc accgttttga ctcccagaac tgtgttctgc 202380 ccactccacg gggtccaggg aggggtctgg ggaagtgccc ccgccaggtc acaccctaaa 202440 caaaggtgag cttgcggggt ttctgcaagg tgtctgggca cctctcaggc cgggcctgtt 202500 tctctgacct ttgccagccg tgcacgtcct tcctgcccag ctctgtggac gcaaacccac 202560 acctgccagc ccgacacctt tctttcctct tctgcactga tctgggccct ggctcccctg 202620 gggtcttggt gtcctctctg cttcctgtag cctcatggga cccggctgct catggccctg 202680 ctgtgctcac agctgcctgg aagctggcag cctgcttcaa gggagggcgg aggtgtgggg 202740 tcccctccta cggcccccac cctgttctgc ctgttgtggg ggacgtgctt gtaccctgag 202800 gattcagggc tgcctcccgg gaagatggct ggagagaaag agaggggaga ggcccaaagg 202860 cagtggccag gctgggactc atctctgtgg gctacggagg ggctgccctg ctccctagcc 202920 agggacaggg tgagaaggac ctgggaacct ctgcgtccca gccatggcac aggccttctt 202980 ccggagcttt ggccccaagg agagggagag gcagcccagc agccctcgcc ttccgtggct 203040 gccactgtga cagccttgcc ctctgggaat ggtgcgcagg aggccacttc acctgtctgg 203100 gcctcttcgc cctttcaacc ctgagaagaa cagtggtcct gattccccac aaaatcactc 203160 cctcccaggg atgccgagtg aggaacaaga cgtggggcag ctctgctctc ctccctcctc 203220 cctcccatgg cagctgtgcc cacctgcaga ggtgcaggca aggtggaggg gcacctgttt 203280 ggaggtccac agaccccggg gagaatccca gctttgtcct aactcagcgg ggtgaggctt 203340 gtgtgtcttc ccctgggctc ctcctctgtg agccttagct tcctcgtcca taaaatggga 203400 tcatcccata aagtgagatc aagcgagcta ggccccgggc agggtcccca acaggttgtg 203460 gttgttcgag aatttgcagc agtggtgatg gtggttgtgg tgatgaggat gatgggggtg 203520 gtaatgacgg tgatgatgat ggggtgatgg tgctagtgga gatgatgggg atgatggtga 203580 tggtggtggt gatagtggtg ggatggtagt ggtgatgtgg gtgatggtga ttgtgatggt 203640 ggtggtggtg gtgatggagg tgatggtgat agtgatcatg agggtgatgg ggatggtggt 203700 ggtggtgatg gtgacagtgg tgggatggta gtgatgatgt gggtgatggt gatggtggtg 203760 atggtggtgg tggtgattgt ggtggtggtg gtgatgatgg tggtgatgat ggtgattgtg 203820 gtgatggtga tggtggtaat tgtgatggtg gtggtggtga tggtggtgat gatggtgatt 203880 gtggtgatgg tggttatgat ggtggtaatt gtgatggtgg tggtgatggt ggtgatgggg 203940 atgatgatgg tgattgtgat gggggtggtg gtggtgattg tgatggtggt gatgtgggtg 204000 gtggtggtga ttgtgatggt ggtgatgtgg gtggtggtgg tgattgtgat ggtggtggtg 204060 gtggttgtga tggtggtgat gtgggtggtg gtggtgattg tgatggtggt gatgtgggtg 204120 gtggtggtga ttgtgatggt ggtggcgatg gtggttgtga tggtggtgat gtgggtggtg 204180 gtgattgtga tggttgtgat tgtgatggtg gtggtggtga tggtgatgat ggtggtgatt 204240 gtgatggtgg tgatgggagt gatgctggtg attgtggtgg tgaagggggt gatggtggtg 204300 attgtgatgg tggtgaaggg ggtgatggtg gtgattgtga tggtggtgaa gggggtgatg 204360 gtggtgattg tggtggtggt aatggtgatg gtggtaaagg ggtgatggtg gtgattgtgg 204420 tgatgtgggt ggtggtggtg atgtgggtgg tggtggtgat tgtgatgggg gtgatgatgg 204480 taatgtgggt gatggtgatt gtggtggtgg tggtgatggt gatgattgtg atggtggtga 204540 agggggtgat ggtggtgatt gtgatggtgg tgattgtgat ggtgatgtgg gtgatggtgg 204600 tgttgatggg ggtgatgatg ttagtagtgg tggtgatagt gatggggatg atggtggtgt 204660 tgatggtgat agtggtggga tggtagtggt gatgtggttg atgatggtgc tggtgctgat 204720 gattgtgatg acagtggtgg tggtgatgag ggtgacggaa gtggtgatga tggcgggagt 204780 gatgggatga tggtaatagc agtgatggta ttgtgatgat ggtgctgatg gggatggtgg 204840 tgatgataag ggtgatgatg atggtgatga taataataaa agtaacaata ataaagggat 204900 acaccttgca gtatcccagt tggcatctcc tagatctaag gtgtcgtggc tggaacattg 204960 acataactcc tgacctgagg ttggccagga cacagacctg gtggacagag agagatggac 205020 gaggagtgtc cgtccttggg ctactaaaca gttcaggcca gggattccca gcaccagcct 205080 ctgtcctccc aggagcccac acttttccta gaaaggtgtt atcaaagtca gaacatcagt 205140 gtaatttagg gtgttttttg tgttgtgttt ttttgagaca gggtctcatt gttgcccagg 205200 ctggagtgca gtggcatggt cttgactcac tgcagcctcc acatcctggg ttcaagtgat 205260 tctcgtgcct caggcatgtg ccaccatacc tggctaattt ttgtgttttt tggtagagac 205320 agggtttcac catgttggcc aagctggtct cgaactcctg acctcaagta atccaccctc 205380 ctcagcctcc caaagtgctg ggattacagg cgtgagccat ctcgcctggc cgatttttgt 205440 ttttttaaaa gacagggtct ctgtcactct ggagtggcaa tgatcctagc tcactgcagc 205500 ctcgcactcc tgggcttgag caattctcct acttcagcct cctgcgtagc tgggactata 205560 ggtgctcgcc actacaccta gccaatgttt acattttgat gtagagacag ggtctctctg 205620 tgttgcccag gctggtcttg aactcctggg ctcaagcaat cctcctgcct cagcctccca 205680 aagtgctggg actacaggca tgagccacca cacctggcct agggtatttt ttttggtgtg 205740 ttgctagcgt agcccaaggc agctctgtgc agggtaaagc aatggggctc cgagtctgga 205800 ggggtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgcg cgcacgcgcg cgcgtgttat 205860 atgtgatttg tttgtgtgtg ttgtgagagt tgtgtgtgag gtatgtgtaa gaggtatgtt 205920 tgaggtgagt tgtgtgtgtg ttgtgagttg tgcatgtgaa gtgtgtgtgt tgtgaggtgt 205980 gtgtatgagg tgtatgtgag ttgtgtgtgt tgtgttgcat atgaatgcta cttcctcatc 206040 ctcgtttgtc tcagtcacct gtggactggc tgtctgcaca cacggtcact gtccctcgag 206100 tggcaccacc ctgcaggcca gcgcccccta gcacatggcc ccacagaccc catgggacat 206160 gcgtgagcct gcctgatgct cacaccagct ccacggggga aggactgttt atcccatttt 206220 gcagatcagg aaactgagac acggtgaggt caggtgactt gcccaggccc tggccggtca 206280 gggaggagca gtttgaacac ctgggctttg gttgcaacca ccctggtgaa ctgcaggaat 206340 cccggccacc tggtgcaccc tgggcagccc tgggctcctc cgccagcccg gcctctgtcc 206400 tgtccaaaat ctgagccacc aggagacctc ctgtccagaa agcacaaggg gcacaagaga 206460 tgccgactct cccaggcccg gctcacctct caggagagga ctgtggcctg ggttgtgctg 206520 gcatcagagc ccggctgtgt gggtttacac agtcactgga cacccggctc gagggtgaag 206580 tcctcggggg ctgcttggca gggatattgc cgggaggtag cccaggcact gctgaatctc 206640 agactggaga gcctcgtgcc tgggtgggag gggccccatg tgcagaccct gctggtctct 206700 ccggagagac ccctgaccgg cctcccatcc tctccccagg gcagagcggc ttgggtaaat 206760 ccaccttaat caacaccctc ttcaaatcca aaatcagccg gaagtcggtg cagcccacct 206820 cagaggagcg catccccaag accatcgaga tcaagtccat cacgcacggt cagtggccgg 206880 gagtgggctg ggggtgcagg acgcccctgc cttcctggag cacaggggtt gggggtcaag 206940 accatcacac acagtcagtg gccaggggcg ggctgggggt gcaggactcc tctgccttcc 207000 tggagcacag agtggggggt caagaccatc acacacagtc agtggccggg agtgggctgg 207060 ggatgcagga cgcccctgcc ttcctggagc acaggggttg ggggtcaaga ccatcacaca 207120 cggtcagtgg ctggggatgg gctggggatg tgggataccc atgccttcct ggagcactgg 207180 tgcggtgtga gggtgcccga gtcaggcaat cccaggtccc caagacgggg actcgctgtg 207240 cccaccatcc ccagcatgtt gagcatgttg gggctctggc tgtgatgggt cagtgtcccg 207300 gacccctgtg ggccccgtca cactgagctc cccacagaca actgagtttt ccaccaaaag 207360 tctgacaggc aaggggctcc caggggaacc gtcaccggcc tgtgccggag ttggctgagg 207420 aaggccatta atttcccggt gtctccttgg ttgtcatcgc tgcctacctg gggttgcccc 207480 ggggtcagtc aggtgtgggg tgtctgtgag ggtcttccgt ctcccctctg actctgcgtc 207540 cgtggctctg tgcagatatt gaggagaaag gcgtccggat gaagctgaca gtgattgaca 207600 caccagggtt cggggaccac atcaacaacg agaactggtg aggcccctcc agggggagga 207660 gcactagcgg gggcttcagg gctccctgga ccccacccag agtcagccct agaggtttcc 207720 cggcccgcgg gggtgcaggg cccacctcct gggacctgac atgctgccaa agccgcacgt 207780 ctcaggggcc tgaaaattct ggaccaaagc agaattacct ggggaatctt gctgtcccca 207840 actcatcacc tgaggccagc ccggggaggc tggtttggga ggccgagggt aaggctgtgg 207900 catctccgct cagcaagcca gacctcccag ggcatgcatt tcattggaag gtggggtgtt 207960 gggctctgag tcctgggaat gcacgacctg cttggggagg gcatctcatg tgcctgctga 208020 ctcgtcccca tcccccacgc agctggcagc ccatcatgaa gttcatcaat gaccagtacg 208080 agaaatacct gcaggaggag gtcaacatca accgcaagaa gcgcatcccg gacacccgcg 208140 tccactgctg cctctacttc atccccgcca ccggccactc gtacgtccct gcagtgtcgg 208200 cgtcctcatg ccgggtgccc tgggttccct ctgtcccctg ggactgcaag acggtgctgt 208260 ctgccctgct gctgggtgca gaggggctga gtcaggggcc atggccgcca gctatgaagt 208320 tgggggtgtg ccatgtctgc acctccaaag cctcacactg acccctatgc aagtgtcctg 208380 cccagccccc atccttcagc tgcgtcttgg ggagctgagg gtcaggcagg ccctgggctg 208440 ttctggagcc tggtggtctg tgtcctgcct tctcaggcca ggctctggca ggtggagtgg 208500 gagcccccag ccaagcaccc gtagcggtga ctgaccttct catccgggcc ctgcctcatg 208560 ggacccctta gagggtttgg tgcgttctta gacgggaagc acagagatca gtgctggccc 208620 cttccagggc tggacggggc tgctgttggt gttggtgaga gccctttcct cccgccggct 208680 ctgtccgcac ctgacgtcgc ccctagagat cagcaagggc gggaggctgc atgtaccctg 208740 gcaggtggac tcttcatggc ctcacggacc ctctgtcctc agctccctgt gcaccccctg 208800 ccagacacct gtggctcacc ctgagccagg gctgggagga ggaggaccag aggccagcag 208860 gagtggctgg tggaggcagc cgtgggtggc ttgtctgcat gggtgggtgg agaaggtcct 208920 tcgcacctgc tgtcccagat gtacttccct gggcggagga agcccagggg tttggggaaa 208980 ccatactctg tgggcaccag gtgcaggaag gagcctggct ggtgggcagc gggcctcacc 209040 cagagtctgt gggaaaaccc aagccggagt tttcgagccc accctctggc atcatcctct 209100 gtgggccagc aggagtcagg ggcagggggc cagcccgctg tccatgggcc tctcctgaac 209160 tgaacatctg ccctcccagg cagaacggct cacctgcggt cctgtggcag ctgttccagc 209220 tgctccaagc tttgcctcag ctgaggctga tggcaggagg cagaagcctc tcctgatgcc 209280 agctgggcaa gccgagggcg ggcgggcggt ctgtggcact tctgccactc cccagcactg 209340 accctttggc tgggactcca gctaggcatg ttgcctggtc ccgcccaagg cgtccagtcc 209400 catggggcag gggcgggcct tggccatctc tgcttaaact tctgcccgga gcgggcttct 209460 ccccagccat gtgtgtgacc gatttattct cactgtggga aaagctcggc tccagaactg 209520 gggaagatgg tgccccagtt ccagggccct gccagcccct gccacccaca gctttcccca 209580 catcagaccc caggctcact ggggccaagc aggcaagggg agcagcccgc ctggtgcagg 209640 ggagcagccc gcctggtgca ggggcaccgc acactggtgc tagcttctat ttctcttgcc 209700 tctcccctcc cagccaaagc cccacagcaa gacggctgct gagccaacga cagcccttct 209760 gtgtggacat gtaggggtgt ggttgggacc ccagaactca tggacgaggg tgcttggagc 209820 tggccctggc ccgcctggcc tgtgcagtgg tgtcacctgt gtctgggaca cacccgtgtc 209880 cttcctctgc cccacactca cagcgtggcc gactcggccc ggggccctgt ccttgccagc 209940 agggaccccc gtgagccccg agccagcacc tgagagtgtc gacacctgct tgggggtggg 210000 tgccccccca ctgccccgct cccccagatg agcctcacgc acatccctct gcttcagcct 210060 caggcccctg gacatcgagt ttatgaaacg cctgagcaag gtggtcaaca tcgtccctgt 210120 catcgccaag gcggacacac tcaccctgga ggagagggtc cacttcaaac agcgggtagg 210180 gttccatctc tacttgcccc agcccttctg tgcaacctgg agacgctgca ggcctggcag 210240 gggccacccc gtctaaagga gtcacactgt cagggagacc gaaccgctgg tcactctccc 210300 cagcgggtgg ctggcctggt ggtccctggc ccaggtggct gctgggggcc gtccctgaga 210360 tggcctctcc agctccccca tatctcaaaa gcagctttgt gggagtgcca attctccagc 210420 agagtctctg aggggggttt tggagaagac ctggaccagg cagatggtga atctctcttc 210480 cagggagtga ggccgagcag gggccgtgcg acatggccca ccttgtttta tgccccccct 210540 tttttttttt gagaaagggt ctggctcagt tgccaaggtt gcaatgtagt ggcacaatca 210600 tggctcactg cagcctccac ctcccaggct cagtccccga gtagctggaa ttacagacgc 210660 acaccaccat gtctggctaa tttttgtatt tttagtagag acgaggtttt gccatgttgc 210720 ccaggctggt ctctaaccct tgggctcaag ggatcctcct gcctcagcct cccaaagtgc 210780 tggggttaca ggcatgagcc acctcacctc gccctgcctg gtttttatta gatggaagag 210840 aagctgggcc aggtgtggtg gctcacgcct gtaatcccag cactttggga ggccgaggcg 210900 ggcagatcac ttgaggtcag gagtttgagg ccaacatgat gaaaccccat ctctactaaa 210960 aatacaaaaa tattagtcgg gcatggtggc gggcgcctgt agtcccagct acttgggagg 211020 ctgaggcagg agaatctctt gaacccggga ggcggaggct tcagtgagcc gagattgagc 211080 cactgcactc cagcctgggt gacagagcga gactccatct caaaaaaaaa aaaaaaaaaa 211140 aaagtttcag gagggatggt ctctgccacc ttcttctccg ccaccgtctg aggcccctgc 211200 tgtgggatag ggaggggcat ccaagcaaga gggcagccct gggctcttcc tcctgacagg 211260 gcagcacatc agagccacat ggggtgcctt tcaaaatgaa accgaggtgc ctgggctgcg 211320 gcaccacatc tgcctcggtg ggtgtgggtg gggcctgtaa cctactccgt cctggggcca 211380 ggtgtcaggg accttcccag catgtgcagg ggaagacagt ccacacaaag tgggtgtgtc 211440 tgccggaggc tacacacggg ctgtggtctg tgcctgggca ggcgagcagc cgctcactgg 211500 gatgtttctg ttgcacgtac ccatgtcggg ctgctggcag ggagctgaga ggttactgca 211560 ggcggggccc ctgctggaac tggggactgt gacgagggtt ttttaggaag ggtttcagga 211620 ggggaggtct cggtaaccct gagtactttc ttggggctgt gatgagcagg agaagagagg 211680 tgggaggtgc tcaggacgat gaccttaagc ccctggggag ttgcagcgtc gctcaggaca 211740 gcaggtgcac ctgcagctgc ccctcttccc tccaggaggc acaggagttg gaggtgattg 211800 gtgtcacagc cccccagagc ctgcccttga acccgagcct ggggcagcac acagtgtgga 211860 ggtcatgtgg caaacaccag tgggtgggta gagcttgcca cagggatggg cccatctctc 211920 tccctcctta tcccagatca ccgcagacct gctgtccaac ggcatcgacg tgtaccccca 211980 gaaggaattt gatgaggact cggaggaccg gctggtgaac gagaagttcc gggtgagtgg 212040 atccactagg atgttgttcc caggggaccc ccagttcctg ctgaagggtg ggttgggggt 212100 ttggaggacc ttaagccatg aaattatatt cttggggcca gagggcactg agcccaggtg 212160 tctgtaccca gtgctgtcag gctgaggctc tcgtttttgg gggaccccag gctcagggca 212220 gctcctcccg ggggcccagg ggagggaatt gccttcccgc acatgtgtaa ccaataccgt 212280 ctgcccgttc cccaggagat gatcccattt gctgtggtgg gcagtgacca cgagtaccag 212340 gtcaacggca agaggatcct tgggaggaag accaagtggg gtaccatcga aggtactcgc 212400 cgcaggcgcc ggggctccag acagatggga agacagtctc ttctgctgac ccagagcctg 212460 tgggccacgc ctgagccagg gactcgtgga acctcatcca ctgccttgcc ccacccagag 212520 ggaggggtct ccttgtcccc attcaaccct tgggaaagtg agagggcaag tggcctgtgc 212580 agatgcctcc accccagacc tccccccggg cagggaaaga ttcagggaga caggagctgg 212640 gatgggggcc gccaagttct ggatcctggt gcaggctctt tcataggcac ctgtgtggcc 212700 ctggacaaat cgcccaacct ctctgggcct agaaaagggg tgggctgtag ctctgtgagc 212760 cagatggacc ctcggcccct taccctgctg aagttcctgg gaccctcaca ccttagtctc 212820 ttgagtggct gttgtaacca attagcacaa acgaggggac ttaaaacaac acaaacgtat 212880 tttcacagtt ccagaggcca gaggtccgaa atcaggggct gtttccttct gaggccctga 212940 ggaccagcct catccatgcc ttcctccttc tggtggcgcc tggcattcct agttgtattg 213000 taaaggcatc acatgctcta atctctgccc cattgtcaca gggccttctt ccctgtgtct 213060 ctgtcccgtc cctcctcttc cttttttttt tttttttttt ttgtttgaga cggagtctcg 213120 ttctgtcacc caggctggag tgcagtgttg caatctcagc tcactgcaac ctctgcctcc 213180 tgggttcaag taattctcct gcctcagcct cccgagtatc tgggattaca gtcacgtacc 213240 acccacctga cttaattttt gtatttttag tagagacagg atttcgccat gttggccagg 213300 ctggtcttaa actcctgacc tcaggtgatc tgcccacctt gcttggcctc ccaaagtgct 213360 gggattacag gaatgagcca ccgagcctgc cctctttcct tcttgtcttt ggacaaggat 213420 gcctgtcttt ggacttaggg cctaccctaa gtggatgatc ccatttggag atccttaatg 213480 aatctataaa gaaagacgtt ttccaagtaa ggtcacaatc atgggttcca aggcctggac 213540 cttgaccatg tctttgaatg gatgggagcc cctggggggc cacagttcaa cccactcctg 213600 gcggtgacac cccgggaggg atgggcccga acgtttcctt ccccttcctc tctctgtccc 213660 ttcatttctc attagaatgg aagaggggaa ggtgcagagg gaaatgcagc aggaaaagcc 213720 actttgttct gggagagcac ttggctgaaa ggcccagtag agcaggaagc acaagtctct 213780 taatcttcca gggcctcagt tttcatcatc cacaaagtgg gtgcagtgtg ccaagatttt 213840 agtgagttga gagactgtcc caaagaccac agagcttttt gggaagctgt tgctctaaaa 213900 aaatggtcat aatgacaatt accaggaggc atcagacact cctgtgccac tggctagaca 213960 tgggttatct cgtttcatgt ccgaagctcc ccgcacccac cctccttgca gagttgaaga 214020 ggtgctgtga gcagaaaacc tgccaaggga cccagaacgg gaggcggctc tagaatctac 214080 agctccagcc ctgcaccaga ctccctcgag atgggagttc atgcctggag gagggtgtgg 214140 agaggcacac gggcctttcc cctgtctgca ctcctcccct accaccaccc ctgccgggcc 214200 caccctgcgg gagctgccca gctgggtgca gcctgggtgt tttccagtat ccgcctgtgg 214260 tgtcaggctg gcttgcctcc ccttggcccc tctgcctgca gttcctctct tcctctctgc 214320 ccaaagagtt cttgctgttt aggaaacttt ttatgaaagg caggtttggg agagttaggg 214380 atggatgggc ctgggacggg ccggcggctt tgctatgggc gtgcctctgc tgcaccctgg 214440 tggccaacct tgagtaccgc aggtggccgg tgacagaaac tgtcaggaaa tgcacaagag 214500 agaggtcccc gcacctctct gacctgtgcg ttgttgagca ccactggctc cagctgagga 214560 agagtctgga acctgtcagg acagttgtga ggtggtgggg cccactttcc agcagtctta 214620 tatgaggacc ctggaaatgt gccttcagca ctgctgggtt tttatatcag gggccccatg 214680 agttcatagc tgacctgaca cccggactag taagggctgt gccttgttct tgcctcccac 214740 ttggtgaaca gcatcttgag gtatctttcc catccttaga aaccacccca agtattgtca 214800 atagaaatgt ggggtgtaat tgatcacgcc atgaactcat ttaatcctca tgtccctgag 214860 aggcgggtga cgttattatc cacattttat ggatgaggaa actgagggaa tgagagtaac 214920 ttgcccgagc cagggagtgg cgatcacaca ctccaactcc agcctgagag ccccattctt 214980 cctgccggct ctcgctgccc gtcagtgtta gatgagagtg ctgctggtca gtctgcagga 215040 ggttctagtg tggacaccgc cctacacagg gccgtggcag gagggcctag gcaaaggcaa 215100 ccggcatagc actgagagca cttgagggct gggcaaggtg gaggccccgg ccctgcctgc 215160 tggcctacca agtaaaaact agacattttt aacttgggga aaagccatgt ggctctgcga 215220 tggggcagcc tggagccagg tgtatgggtt ctgcatcccg ctccagcctt atgcactgtg 215280 gagctgagac agacacagtt cttgcgttct ctatgcctca ttttcttttc ttttcttttt 215340 ctttttcttt tttttttttt ttgagacgaa gtttcactct tttgcccagg ctggagtgcc 215400 gtggcgtgat cttggctcac cacaacctcc acctcctggg ttccagtgat tctcctgcct 215460 cagcctcctg agtagctggg attacaggcg cctggtacca ggcctggcta atttttgtat 215520 ttttaacaga gacgagattt catcatgttg gccaggctgg tctcgaactc ctgacctcgt 215580 gatccaccca cctcagcctc ccaaagtgct gggattgcag acgtgagccg tggtgcccag 215640 cgtctacgcc ccattttcgt aagataatgg ggataacaaa ggaatcacaa gagacacttg 215700 caggtgtgtg aagacgaagt tcatcacatg ggagggcacc gggtgtcttt atttgccttc 215760 cctgcccggc tccccacctc cagtgatgcc gttcactgcc ctccttgtta aaaggccttc 215820 tgttatataa cagttacaca tgccaggcac cgcgtgttca tataggagtt acgaagcaca 215880 gcaataaaat gaccactctg agatggccac cagctcgagc ccgagggcac ttgtgggtgc 215940 ccgtggtctc ctgcccagtc tccctgagaa gtggccactg tcccgagctt gggcttgtat 216000 gtattgtgtg aagtgcacat gtccctgagc aatgtttagc attgctgatt cttgagcttg 216060 tgaatggtcg tccacagtac gtagcccctg tgtgtgtccc tgtgtgtgtg tgctctgagc 216120 gcacacaagg tggatggggc cgtgggggta acaccctgtg ggccacaggt tttctttaaa 216180 atcccagctc cgattcctgc ttcatcccat tcccagcagc ccagccccct gcctgtcttc 216240 aggcccctgc tgggacgtcc tgctctccct ggtcacccca gtggtgcggg ggcccactgc 216300 cctggcttct ccactgtggc ttccttccat gctcctattt ggcctggtca ctgtgccatc 216360 tcccattagc caggaacttt ctggagagca ggagctgagc tgtccaggag caggagctgg 216420 tgctggtcac tccagtatcc cccagactga gggcagtgcc aggtgtccta tactcagctg 216480 cagagcaggt ggttcccctg ccctcctgcc catggggctg ccctcagact ctgcttttgg 216540 caccagcatt tctgggcagg gggagagagg tggggtccgg gcagagtttc tccactggga 216600 cattaaagcc cctcctgtct cctctcctag ttgaaaacac cacacactgt gagtttgcct 216660 acctgcggga ccttctcatc aggtgagaga cagggtgctt gggtggggct gacggcttca 216720 cccctaagag ggccctacag cgggtggggg cagtgggtgt ggggccgaag ccctgggcag 216780 agtgggtgcc ccctgccacc tgcctgccct gccctcggga agatcttgga agcccatctt 216840 ctgaaaaaga aaacccactg ggaaatgaag caggcagtga agatcctttt caacccctgc 216900 gaagttggct ggatgggaag gctgagcttt gatccactgt ggtctggccc gttagagctg 216960 cccggtggcc actaagggcc cagtgaggcc tcatgtgcag gccctgccgg cagcgtgggg 217020 cgtctccagc tccgatccca ctggcctctg acccctaccc ctttcacctg gctgaggctt 217080 ctccttgttt cccttgagtc caggcaagga ggggaagccc tgatggagag ggtgctgggt 217140 gggtggtccc tggagtgtgg gccctggcct gggcaggttc ttcctcagca agcagctggc 217200 atggatgatg ggaatgttat caagaggagg ggcctccagg ttggcggggg caggggtggg 217260 gggattccgg gagccgttct gccattgtgg ggatactggg ctttccaacc tccctccaga 217320 ttattcctcc tgagctgcag aggaatgaaa atccgagccc aggacttttt tttcctgggg 217380 acaagggcaa cccagccctt tgccccaggc cacctgcctg ccacaggcca tagtcctgga 217440 ggccggtggt cacccactgc ttccaccctg ccagcaccct ggacaccggc ctggagcaac 217500 aatgctccag ccctgtccct ctgagtctat gcactgtccc tgggccctgg acccagggcc 217560 atagggtgga cccagaggga gacacatgca ctggaatatg tgtgttctga ccgagtctgg 217620 gcttaccagg gggactgacc cttcccccaa aacgtgtacc agatctggtc caacatggtg 217680 ggcctggggg accccatggg gagccaagca gtcgggatgg ggagtggggg tgggggcagg 217740 cgggcctgag tccgaggcag gccgagcagg gcccctgccc cgctgccccc accccgctgc 217800 gcccacctca ctgacccgcc cgccccccac ccccacagga cgcacatgca gaacatcaag 217860 gacatcacca gcagcatcca cttcgaggcg taccgtgtga agcgcctcaa cgagggcagc 217920 agcgccatgg ccaacggcat ggaggagaag gagccagaag ccccggagat gtagacgcca 217980 ccctgcccac ccccgggatc ctgcccccaa gtcatttccg tcccccccca ggccctccca 218040 ccaccccatt ttattttata tgattttctc catttgtcat cgttccccac cccttcgaca 218100 tgctgccagg aaacaaggga aggggcctcc ctccgagtga gtcagtgatg aggccgcggc 218160 ctccccgagg ttgtggggag gctgcactgg agccacaggc aggggtgaga gcacccactg 218220 aattgacatg accctctgtc cccaggcctg gctccccgag ggctcagaag agcagcttcg 218280 gtgtgcagat catccgtctg tgtggggttc tcagtgccgg aggccttggg gtgggggcca 218340 ggcctcgcac ttgcagagga gcccagtggg ctgcacgctc ccctccatcc ccatcggccc 218400 tgtcccctgg agtgtgtcag agcccagggg agaatgcagc ccaccaggag cacctggacc 218460 ccctgcccgc cacatggtgt ggccatcact cagcccctac ccctgccctg ctcctaaggg 218520 tagaaaactc cagggtcccc tgccaccgac tgcccagcca ctccaagccc cctggcagct 218580 gcccctcctg gagcagaaag tgcctttatc tcagccatcc gcagactgct tggccagatg 218640 cggggacagg ctggaatgag ggaggcgtct tcatctccct gccatccccc tctcacgcca 218700 cccccgcccc caccgggctg caggtgctgc tgatgcgctg ggatctgatt gaggataaaa 218760 aggaaggaga gatgacccct accccctcat cccccagttt tgaaaaggtc taagcaagtg 218820 agtctggtgg aggagctgag ggagggagcc atggaaggtg ccagaaggaa ggttggcggg 218880 ggcacgtgtg ggccgtggct tgggctggtc agagtggcgt gagctgcccg gcgcctgccc 218940 tgcccaagtg accagggaag tgtgtgtgtg tccatgtgta tgcgtgtccg tctgtctgtc 219000 tagtgtctgg gtttggccca agactgggct gtagttacat taatgcccag ccagccaccc 219060 ctgccactca cccttcctgg cccaggcctt gctgactctc tgagctgggg aggtgggagg 219120 ccaggcgagc ctgactctgt tgatctaccc gtgcctgggc ccctcccctc agagcccatg 219180 gtaacgaacc cctagaaagg agagaacggg cgtcaggggt gcacagtcca cagctgaaga 219240 gcaaggtttc gtggcagcac ggcccggccc ctcaccctct gtccccacga ggggacccat 219300 gggggctgtc tttgcagggc acagatgacc aaagtccctt cctgcttcct gttacctgtc 219360 ttgctcctgg ggagaaagag gggcctgatg agactccact caggtgcaca catcaccagg 219420 tgcatctgca ggcaccgggc tggctgcttg cagccaggag aaggtcagcg agaaggagtg 219480 tatgagtgtg agtgtgtgtg catggaagtt ggggcactgg gcgtctgact ccctccccac 219540 ccaagagagg aaggacccct caccaccccc actggtgaga cagtttactt tgccaacttg 219600 ccatgttttt gccaaaacca agattttgaa ggaaatgagt ggccagcgcc agggcccagg 219660 ccatgtggcc tgcccagcct caatgtcact tggtggcggg gtggggtggg ggtgggcagc 219720 agcatcccag ccttgagatg cttcactttc cttctctgta accagacttt gaaaaattgt 219780 tcgtttcatc aggctctgtt cctcaatggc cttttgctac gtgcctcccg agaaatttgt 219840 ctttttgtat aaatgacaaa gtgttgaaaa tgtatttcct gaaataaatg tttcaaatgc 219900 agaaaccca 219909 <210> 2 <211> 1405 <212> DNA <213> Homo Sapiens <400> 2 cgttacccga gttgtaaagg gcggctccct gtgtctgccc cgctgcaccg atacaccgag 60 ctgcgcacgg tgcccagcgc agggagaaca aatgatcatc tgtccaacgc gcccatttac 120 aggtgaggaa actaaggctc caactcaatc gacgcactct gcccttttga ttaccagaaa 180 agtagcagga caggtgtcct gtcccgccct accccggccc actaagccgg caccccggct 240 ccgacccccg gctgtgcccg gcgccgccgc ggtgcccggc gccgccgcct cgcccggcgg 300 ggccgcccgg agcgcccgca cctccgcccg cttccacctg gccgggcccg ccccgcccgg 360 actcgggact gggaagtgcg gcgactcccg gaaccagcca ttggcgccag cgcggggagc 420 tgggggtgca gagctgcggg cgcggcgggc cacgcaggcg gcccccaccc ccggcctggc 480 ctggtctggt ctggtctgcg ctgccgcgcg ggggcgcccc ctcccaggcc cggcgcccgc 540 cagccccgct ccgccaggtg cagcgcagcg caggggtggg cgggggtggg gctcggcgcg 600 cacgttcacg gggcggggag ggggcgggtc aggggcggga ccacagccgg ctgggccggg 660 gttctatgcg catctccggg gaggggcggg gcgggggcgg ggccggggcg gggcccggtc 720 ggtgcactcc agacggcggg ccgccccctc ttcccgcctt cctactaccg gcccaggatt 780 agcgccctgg gagcgcgcgc cccgctgcct cgccgccaca ctttcctggg agcggcggcc 840 acggaggcac catgaagaag tcttactcag gtgggcttcg cgcccggggt ggggaggggt 900 cggtgtcccg ggaccagcgc tgctcacctg agtgcctgcg gccgggagtg gcgaggcgcc 960 cccggagctg agcgagtccc cgcggcgggc acactgcagg tcgagttcct cccaggacag 1020 ggccgctgtc gggccgcttt cgacctgagc cgaccgtccc ctgcgctgtc tccagccctt 1080 gctcgagtgt cggaggggct gccctggggg acgctccctc ttcctcgccc cttgcaccct 1140 cgcaggaatc gctgactttc caggtcggcc gggtgctttg ggtccctgtg cgtctgtgtg 1200 ggtgaatggg gtcggggcta ggtggagggg tgtccttggg ttcagcctct agggctggtg 1260 gtccaggccg cagcatcctt tcttcggatt ctcttcggtt tctcctctac ttagtggggc 1320 acgggacggc ctccagatgg gaccgtccag cagcgcccaa acttggcgac tcgggttcac 1380 gttttgcgct caggacgccg cccgc 1405 <210> 3 <211> 2365 <212> DNA <213> Homo Sapiens <400> 3 gtggtcgtgg tgggggtgtt agctgcaggg gtgccctcgg tgggtgggag ttggtggcct 60 ctcgctggtg ccatgggact cgcatgttcg ccctgcgccc ctcggctctt gagcccacag 120 gccgggatcc tgcctgccag ccgcgtgcgc tgccgtttaa cccttgcagg cgcagagcgc 180 gcggcggcgg tgacagagaa ctttgtttgg ctgcccaaat acagcctcct gcagaaggac 240 cctgcgcccg gggaagggga ggaatctctt cccctctggg cgcccgccct cctcgccatg 300 gcccggcctc cacatccgcc cacatctggc cgcagcgggg cgcccggggg gaggggctga 360 ggccgcgtct ctcgccgtcc cctgggcgcg ggccaggcgg ggaggagggg ggcgctccgg 420 tcgtgtgccc aggactgtcc cccagcggcc actcgggccc cagcccccca ggcctggcct 480 tgacaggcgg gcggagcagc cagtgcgaga cagggaggcc ggtgcgggtg cgggaacctg 540 atccgcccgg gaggcggggg cggggcgggg gcgcagcgcg cggggagggg ccggcgcccg 600 ccttcctccc ccattcattc agctgagcca gggggcctag gggctcctcc ggcggctagc 660 tctgcactgc aggagcgcgg gcgcggcgcc ccagccagcg cgcagggccc gggccccgcc 720 gggggcgctt cctcgccgct gccctccgcg cgacccgctg cccaccagcc atcatgtcgg 780 accccgcggt caacgcgcag ctggatggga tcatttcgga cttcgaaggt gggtgctggg 840 ctggctgctg cggccgcgga cgtgctggag aggaccctgc gggtgggcct ggcgcgggac 900 gggggtgcgc tgaggggaga cgggagtgcg ctgaggggag acgggacccc taatccaggc 960 gccctcccgc tgagagcgcc gcgcgccccc ggccccgtgc ccgcgccgcc tacgtggggg 1020 accctgttag gggcacccgc gtagaccctg cgcgccctca caggaccctg tgctcgttct 1080 gcgcactgcc gcctgggttt ccttcctttt attgttgttt gtgtttgcca agcgacagcg 1140 acctcctcga gggctcgcga ggctgcctcg gaactctcca ggacgcacag tttcactctg 1200 ggaaatccat cggtcccctc cctttggctc tccccggcgg ctctcgggcc ccgcttggac 1260 ccggcaacgg gatagggagg tcgttcctca cctccgactg agtggacagc cgcgtcctgc 1320 tcgggtggac agccctcccc tcccccacgc cagtttcggg gccgccaagt tgtgcagccc 1380 gtgggccggg agcaccgaac ggacacagcc caggtcgtgg cagggtctag agtgggatgt 1440 cccatggccc ccatccaggc ctggggatat cctcatccgc ctcccagaat cgggccgtgg 1500 gggacagaag gggcctgcgt gcgggcaggg agagtatttt ggctctctcc tgtcttcggg 1560 gtttacaaag tgtgttggga cttgcggggc tgctctgtcc aagcctgggt ctggcgtccg 1620 cgtctctgag cctgtgagtg cgtgcgcttt cctgcgtcct cttgactgcc ggtgctgggg 1680 ctctgcgtcc tgcgtccgcg ggagtaaata cagcaggcga aggggaagct cacacaatgg 1740 tctccagcgc tctggggcag ggcttctgag gggcgggcct gcctctgccg ggacctggag 1800 cccccgcccc tcggagaggc tcctaggctg acttgggcag agccctctgg tgggccggga 1860 gggggaaagg ctgtgttgaa atgagcaaac tgtccaggtg tcaggccaag ctgggaggtg 1920 accagcctga ggtcctcccc gctccatggc cagaaccagg gctgacatct gggtgtcctg 1980 agcccagctg cccacacggc ccacctgggg tcagccctat ctgagtgggg gaggcggggc 2040 ctcctggggg accagaactt tggctggacg ccaagcagag tgccagtggc tgttcttcag 2100 ggctgggcct gaggagggtg tggggcggcg aagggacggg agggggttgt gatccagtgg 2160 ccactggcgc tgtgcagagt gtgagctgga aacatcgtag ttactttgtc agcttagtgg 2220 tgaaagccct ttttcaggct ctatcccttt gcatccctgc ttcccagagg gaggggaggt 2280 ctgggtctgc agagctggga gggcttgctg ttcccgcccc cctcccccac aacacctcct 2340 catctggaca tctttgggca catgc 2365 <210> 4 <211> 219909 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 4 cgttattcga gttgtaaagg gcggtttttt gtgtttgttt cgttgtatcg atatatcgag 60 ttgcgtacgg tgtttagcgt agggagaata aatgattatt tgtttaacgc gtttatttat 120 aggtgaggaa attaaggttt taatttaatc gacgtatttt gtttttttga ttattagaaa 180 agtagtagga taggtgtttt gtttcgtttt atttcggttt attaagtcgg tatttcggtt 240 tcgattttcg gttgtgttcg gcgtcgtcgc ggtgttcggc gtcgtcgttt cgttcggcgg 300 ggtcgttcgg agcgttcgta ttttcgttcg tttttatttg gtcgggttcg tttcgttcgg 360 attcgggatt gggaagtgcg gcgattttcg gaattagtta ttggcgttag cgcggggagt 420 tgggggtgta gagttgcggg cgcggcgggt tacgtaggcg gtttttattt tcggtttggt 480 ttggtttggt ttggtttgcg ttgtcgcgcg ggggcgtttt tttttaggtt cggcgttcgt 540 tagtttcgtt tcgttaggtg tagcgtagcg taggggtggg cgggggtggg gttcggcgcg 600 tacgtttacg gggcggggag ggggcgggtt aggggcggga ttatagtcgg ttgggtcggg 660 gttttatgcg tattttcggg gaggggcggg gcgggggcgg ggtcggggcg gggttcggtc 720 ggtgtatttt agacggcggg tcgttttttt ttttcgtttt tttattatcg gtttaggatt 780 agcgttttgg gagcgcgcgt ttcgttgttt cgtcgttata tttttttggg agcggcggtt 840 acggaggtat tatgaagaag ttttatttag gtgggtttcg cgttcggggt ggggaggggt 900 cggtgtttcg ggattagcgt tgtttatttg agtgtttgcg gtcgggagtg gcgaggcgtt 960 ttcggagttg agcgagtttt cgcggcgggt atattgtagg tcgagttttt tttaggatag 1020 ggtcgttgtc gggtcgtttt cgatttgagt cgatcgtttt ttgcgttgtt tttagttttt 1080 gttcgagtgt cggaggggtt gttttggggg acgttttttt tttttcgttt tttgtatttt 1140 cgtaggaatc gttgattttt taggtcggtc gggtgttttg ggtttttgtg cgtttgtgtg 1200 ggtgaatggg gtcggggtta ggtggagggg tgtttttggg tttagttttt agggttggtg 1260 gtttaggtcg tagtattttt ttttcggatt tttttcggtt ttttttttat ttagtggggt 1320 acgggacggt ttttagatgg gatcgtttag tagcgtttaa atttggcgat tcgggtttac 1380 gttttgcgtt taggacgtcg ttcgcggttg atatttttat tttattttag tagggttcgt 1440 tttaagtagg cgaagggggt ttgatttggg ttttattatg agtcggttta ggagttttta 1500 ttttataaga ggttttcgtt ttggtatttt gaagttttat tttatagatg ggtatatcga 1560 ggttataagg gtaggttaag agaaatttag atttttatta tttgtttttt tttttttttt 1620 tttttttttt tgtggttttt tttaaaggat ttaggtaggt aggatttttt gtttttttta 1680 gtttttaaat tataaatagc gttttttttt ttaaatttag aaatcgtttg tttaatgttt 1740 tttttttaat ttatttagat agaaaggtat ttgttaagga tttatgaatt aatttttatt 1800 gataggagaa tagaattatg ggttttagtt ggaggtgaag gagttatcgg ggttattttt 1860 ttgtttttgg gttattgtcg gttttttttg gttttttata tttaggaatt aaaatgagtg 1920 ataaagtatt ttgttttaaa gaggattatt tagaattttt tcgaaaatat ttttttgggt 1980 tagtagttta gaattttaat ttttattcgg ttgttgcgaa taagatggtt ttttacgtat 2040 tcggagtata gttttgttag gagcgtgggt gggttggtgt gttggtgggc gggagcgggt 2100 ttttaggtgg tatatgtttg gttttggtat cggggttttt tttttaatat gttttaaata 2160 tttgagattg ttgtggggat cgcgcggtgt atggtttttt ttaggggatt tttagttcgt 2220 ttagggaggg ttttttgttt ttggtttttt atattttatt ttttattggt gggtttagat 2280 agtgggggtg atcggggttt ttttaggtcg tgggttttgg gttttttttg cggagatttt 2340 tttgtataga tgtcggaagg gttttgaggt aggtttggag tttttgtatt tgcggtttat 2400 tgggaggtgg ggagattatt atttgttttt tttttttttt ttttatatat atttatttta 2460 ttttttattg ggtttttttt tttttttttt ttttaaaaaa aaggatagaa ttttttgtag 2520 taggtggaag tagagtttgt ggagtgagta ggaattaatt tttgtatagt agtttcggtg 2580 tttttttgtg tttatttaaa ggggtaggtt tttttgagga tgggggaagg gagggtttag 2640 attatttttg gtttgttttt tgtttggtag tggtttaagg tgtgttgggt tattgtgttg 2700 tagttgtatg gagtgggatt ggagggggtt gatggtgggg gtggtttttt gtttttattt 2760 tgagtgtttt ggagttgttt tggtattagt tttttttcgg gtacgggtat tcgtaggagt 2820 taggttgatt ttttaataag ttatcgatat tatgaaatta aggaaagtag taaaagatgt 2880 taaaaatttt ttaaggtttt gataatttaa ggataatagg aaggttttta tttttttatt 2940 tagattgtgc gggattattg tttttagatt tgtatgtggg ttttagaata aacggaatga 3000 ttataatgtt gttttcggta gatttggttt gaatattcgt gagtttttga aaaggagaaa 3060 gattttagaa ggatgtgttg gggtaatttt aagtatcgtg ggtttataga tagttatcga 3120 agatatttta tgtgttgggt atatatggtt aagtttgagt gggtatagaa atggtaatga 3180 gatatagttt ttgtttgtag agaatttata tttttatcgg gagttaggat gagggcgaga 3240 tattagttta ttaatatttt ttttttttga gtagtttagt ttttaaatat tataggaatg 3300 tttcggaggt tttaggtgga ggtgagattg agttgggttt tgaggaagga gaagttttga 3360 gtagtggaga ataaaaaggg atttggttag gtgcgtttga agttttagtt atttaggagg 3420 ttgagatacg aggatcgttt gagtttagga ggttatttag gaggttgaga tacgaggatc 3480 gtttgagttt aggaggttat ttaggaggtt gagataggag gatcgtttga agttaggagt 3540 ttaaggttgt agttttgtga tagcgtttgg aaatagatac ggtattttag tttgggtggc 3600 gttatgagat tttatttgta agaaggtttt ttttaatgcg gaaggtagta agggtttata 3660 tagggtagtt gtaggattta gggggatatt ggggataggt tttttttggt agttttattg 3720 ttgttttagg ttttttcgat tgttttattc ggttttttaa tggggtggag gtagtggtag 3780 tttataggta gtgtggttta gtggttatat ttgggggttt agagtcgtta gttttttggg 3840 attaaatttt attaggttgc gttttttttt gtggtataag gtttttattt tatgtatttt 3900 atttgtttta tttgtttttt tgtgtgtgtg gtgtttttta attttattta tttatttatt 3960 tttgagacgg agttttattt tgttttttag gttggagtgt aatggtatga ttttagttta 4020 ttgtaatttt cgttttttag gtttaagtga tttttttgtt ttagtttttt gagtggttgg 4080 gattgtagga acgtgttatt gcgtttagtt aatttttata tttttattag agatggggtt 4140 ttattatgtt ggttaggttg atttcgaatt tttgatttcg tgatttgttt gttttggttt 4200 tttaaagtgt tgtgattata ggtatgagtt attacgttta gtttgtttta tttgttaaat 4260 gggatagtgt tatgttgttg taaaggttaa acgagtttat atttgaaaaa gttgagaaat 4320 gtttgttttg taatttgtta gttgttgtta tgattatgat tgttattgat aggaggatgg 4380 agaaggttgg ggttacgtta ttgttaggac gttttagaag tttttatgat ttttttttat 4440 tgtggttaga gtatggtgta gggttttttt tttagttttt tagtattgga gttagttgta 4500 ttgtattcgt tttggttttt taggttttga gttttgggat tttttttgta tattaggtta 4560 tatggaattt gtcgttattt ttaggttttt ttggaaattt tttgtgggtg gtagcggtag 4620 gaggatttat tcgaggtcga tgagttatag aagcgggatt gaggttgcgt tatattttta 4680 ttggtatttg ggaattattt tggagatttt ttttttattt tttatttttt tgagatggag 4740 ttttgttttg ttgtttaggt tggagtgtag tggtacgatt tcggtttatt gtaatttttg 4800 ttttttaggt ttaagtaatt tttatgtttt agttttttga gtagttggga ttataggtat 4860 gtgttatcgt gtttagttaa tttttgtatt ttttagtaga gatggggttt tattatattg 4920 gttaggttgg tttcgaattt cggattttag gtgatttatt cgttttagtt ttttaaagtg 4980 ttgggattat aggtatgagt tatcgtgttt agttattttg gagttttttt gtggttttta 5040 ggagattttt gaaggggtat tagttacgat taaaaagttt tatgttgtcg tgatttttga 5100 gttttgggta gggagggagg ttgtatttat ataggaagta gtttttgtcg tgatttagtg 5160 tgttggttcg tcgtggtgga tagggttgta tttttattta gcgtttcggg agttgattta 5220 cgggaagggt aaggaattgt atttttagag aatatttttt tagttagtta attcggtgat 5280 aggcgagcgt gggaagggta taagtatagg gttttttttt tttttttttt agtttcgttt 5340 tcgcgtttgt tttcgttgtt ttttgttttt ttacgtttaa gtttgtttgt tttggcgtat 5400 ttaggggatt tggattggag agaaaaagtt atttcgtacg gttagtttgt ggttttgttt 5460 gatttgtgtt tttcgtcgag gttttttagt tgtgagatag ttggttgagt ttaagttttg 5520 gggttagttt tttttttagt ttgttgtaaa ggtagaaagg tatgtttagg taggggttat 5580 ttgttttgtt cgtttacgtt agatcgtagg tatttgttcg ttagattttt tcggtttgtt 5640 tagagggatt ttgatagtcg agggtaatgt atttggtagc ggagtattgc gtttgcgata 5700 gtttattttt tttttggaat tattttttat aagtgtgatt agtttaagtt aggataggta 5760 tagggggatt taggattgtt atttaggggt agtggtttgg aatttaggtt taggtgatat 5820 gggagttaat tttttgtttg gagattttag gtgggtgttt gtagaggata ttttatttga 5880 ggatttatgg aaggggatat tttttatttt ttatttggtt tttgggttgt ttttttttga 5940 tatttttttg ttattttagg tagttttgat agttttatgt gattgggatt tagaggtggt 6000 ttttgttttc gttttagtgt ttgtttatag gtagtgttgc gtgggttttg aagtttgttt 6060 aagatggatt tgataagggg agtttagtat atattagtgt aggttcggtt agggggtgat 6120 gatggtagtt tttgggtaga tttagttggt tttagggtag gaggggtttt agagagaggt 6180 tttaggtttt taggggtgtg aatttttggg gtgaggcggg aagtgacgcg ttgggttttt 6240 gcgtttttgt ttgttggagt tattattttg gaaatatttt agttttaggc ggttgttagg 6300 gatttatggg gattagtggg tgttaatttt tgggtgaagt tttcggggtt tgtatatagt 6360 atatagcgtt gtggttttat ggtttatttt gttgtgtgaa gtggtttagt tttcgggaga 6420 gtttttagtt aggtaggttt gacggtaatt gttaggttat ggtgatttgg aatcgttgat 6480 taaagggagt tagttttggt gggtggaggg atttggtggg tagttatcgt gatgttaggt 6540 atggggatcg tgtgttattt aggtttgtgg gtgtcgagtt tttgtgggag tagtgaagtg 6600 ttttcgtggt cgatgggttg gttatttttg tttttttttt gatgtgatag ttgtgtttgg 6660 gtttcgggaa atttgttagg aggtttggta ttggtttgtt ttattggagc ggttttgttg 6720 agttgtgagt tgttcgtttt tttgaggttt ttagtttatt ttaatttttt atgtggattt 6780 ggttatttat tttagaagcg tttgtcgggc gttgttgagt gttaggtttt gtttgttttt 6840 ttttttgtac gttggaggtt ttgggtatta gttttgtagg gtggtttggt tttgggtttt 6900 tagggtagag tatggtattt tttgttttta gtttagtttt tttttgtttt atttttttga 6960 ttttattttg ggtatgggtt tatttgtagt ttttgtgaag ggagatattg agttgttgtt 7020 ggtagaggag gggcggtttt tgggtattgt ttgttaatgg tttttcggta gttttgtgat 7080 agttgagttt tgtttttagt ttaatttgat ttggtttttt aaagtatgat tgttggtagt 7140 ttgaaaattt ttaggatagg aaataggagt ggcgtaggga atgtaagatg attttagttt 7200 taagttattg ggcggttttt agatttaggt tgtttgttgt ttttggtagg aatttaagtc 7260 gttggttatt tttagagcgg tgttggttcg gggtttttag tggtttttgt gtttgggtga 7320 gaggaatttt ggatggttat tttgttttga gtgtgtgggt ttttagaagt gttgggttag 7380 ggggtacgga gggttagaaa gttttttttg gagcgttgga ttttttcgtt gatttttatt 7440 ttatttcggt ttggggtttt agagaagggg tttaggtagg agtgttattt ttttttaatg 7500 gggatgtggt tttagttttt gtttaggtgg gtgtattgtt tttttttcgg ttttttttag 7560 gttgtttaaa tgatttgtga cgaggtttgc gttatggtcg gggttttttg ttttttttag 7620 cgttgtattt gggaattagg ggttgggttt cggaagtcga ggatgttttt gaatgttatg 7680 tttgggtatt tgttttggtt aggcgaggcg tgttggggta gcggttgaga tgggagtagt 7740 agtattgttt gttaggtttg agatgggttt cgggtgagtg tggttattag gaagggttgg 7800 gtagagtagg cgggtgggtc gtttttgggg ttttgtttcg tagattaatt tgattcgtat 7860 tttggggtcg gggttttttt ttatagtttt tttatgaatt atggtttttg tttttatttt 7920 aaattagatt ttagaagagg aataatgttt atgtaattta agttagttgg aagtgggtta 7980 tatttaattt ttgttatttt ttagtttgtt aaggatttga ttaatttaat ttagagggat 8040 ttggagggtt gtttgtaaaa tttattaata atagggaatt ttagttttgt agttataggg 8100 tttatagagg tgtcgggttg tcgggttatt gttgggaggt gagtcggtgg cgtagatatt 8160 atggaggtat cggtagtgga agagttgtaa gtgtatatag aggtcggtat cgaggggcgg 8220 ggaggaggag gtggtggatt tttcgttagt gttggtatta tgttgttttt agtattagag 8280 atttaaggtg tggttgattt tggttggggc gatgagttat tggatagtag agtttttttg 8340 gtagttgggg gttaacgttt taattgtcgg gattttgtat tatgtcgttt tttttttttg 8400 ttttgtttgg tttggtttgg tttggttttt gagacggagt tttattttgt tatttaggtt 8460 ggagtgtggt ggtttaattt tggtttattg taatttttgt tttttgggtt taagtaattt 8520 ttttgtttta gttttttgaa tagttgggat tataggtacg cgttattatg tttggttaat 8580 ttttgtattt ttagtagaga tggggtttcg ttatgttggt cgggttggtt ttaaattttt 8640 gattttaggt gatttatttg tttcggtttt ttaaagtgtt gggattatag gtatgagtta 8700 tcgcgtttag tttgtattta tgtttttttt tttttttttt tgagatggag tttcgttttt 8760 gttgtttagg ttggagtgta aaggcgcgat tttagtttat tgtaattttt atttttcggg 8820 tttaagcgat ttttttgttt tagtttttta agtagttggg attataggtt tgcgttatta 8880 tgttcggtta attttgtatt tttagtatag acggggtgtt tttatgttgg ttaggttggt 8940 ttcgaatttt cgattttagg tgattcgttc gttttggttt tttaaagtgt tgggattata 9000 ggcgtgagtt atcgtattcg gtttatgttt tttattatta ttatttaatt ttttaaggaa 9060 agtaatttaa attgtatatt gtattttttt tttttttttt gttttttgtt gttagttttt 9120 tgtattattt attgttaaat aatatgaata ggaaattgaa aggaaaattt taataattat 9180 tggttgtagt attttttttg tgttttattt agtgtttgtt tttttaggaa tatgatatag 9240 ggtttgattt aattatgaaa ggcgtatatt tttagagttt tatatttttt atagaatgaa 9300 tgttgaattt tgtttttttt atttgaaatt agattttagg tatggatttt atgattatta 9360 ttataatggt tttttagagt ggatattgta ttttgtaggg aattattttt tttttagttg 9420 ttggtgtgga cgtttttttt tgatggtgtg ggtttgggtt tttgaagggt ggtgttttga 9480 gtaaagatgt tatagtagtt atgtttatag ttttgggttt ggggttaggt ggagattggt 9540 tttaatttta gagtttgttg ttttaaaata aatttttttt tttttttttt tgagatggag 9600 tttcgttttg ttgtttaggt tggagtgtag tggcgcgatt ttcgtttatt gtaagtttcg 9660 tttttcgggt ttatattatt tttttgtttt agtatttcgt atagttggga ttataggtat 9720 tcgtttttac gttcggttaa ttttttgtat ttttttagta gaggcggggt tttattatgt 9780 tagttaggat ggttttaatt ttttgatttc gtgatttatt cgttttagtt tttaaagtgt 9840 tgggataaaa taaattttta gggtcgggag cggtggttta tatttgtaat tttagtattt 9900 tgagaggtcg aggcgggtag attataaggt tagaagatcg agattatggt gaaatttcgt 9960 ttttattaaa aatataaaaa attagttggg tgtagtggcg ggcgtttgta gttttagtta 10020 ttcgggaggt tgaggtagga gaatggtatg aattcggaag gcggagtttg tagtgagtcg 10080 agattgcgtt agtgtatttt agtttgggcg atagagtgag attttgtttt ataaataaat 10140 aaataaataa ataaataaat aaatttttat atttatttgt attatttatt attattatta 10200 ttaaataggg ttttgttgtg ttgtttaggt tggagtgtag tggcgtgatt atgatttttt 10260 agtttcgatt ttttagtttt aattggtttt ttttttttag ttttttgagt agttgggatt 10320 ataggtgtgc gttgtatgtt tggttaattt tttttttttt tttttttttg agatagagtt 10380 ttattttgtt gtttaggttg gagtgtcgtg gtgtaatttc ggtttattgt aattttcggt 10440 ttttggatta aagtaatttt tttgttttag ttttttgaat agttgcgatt ataggtatgt 10500 gtcgttatat ttggttaatt tttgtatttt tagtagggac ggggttttat tatgttggtt 10560 aggttggttt taaatttttg atttcgtgat ttatttgttt tggtttttta aagtgttggg 10620 attataggtg ggagttatcg cgtttggtat gtttggttaa tttttaaaaa atttttgtag 10680 tagtcgggcg cggtggttta tgtttgtaat tttagtattt tgggaggtta aggaggtcgg 10740 gagttcgaga ttagtttgat taatatggag aaattttgtt tttattaaaa ttataaaatt 10800 agttgggtat ggtggtatat gtttgtaatt ttagttattt aggaggttga ggtaggagaa 10860 ttgtttgaat ttaggaggcg ggggttgtag tgagttgaga tcgtgttacg gtattttagt 10920 ttgggtaaag agagtgaaat ttcgttttaa aaaatttttg tttttgtttt tgtagcgata 10980 gggttttgtt ttgttgttgt ttaggttggt attgaatttt tagttttaag cgattttttt 11040 gttttagttt tttaaagcgt tgggagtata ggcgtgagtt attgtgtttg gtttttattt 11100 gttttggttg tttttttttg ttttaggtaa ttatatattt ttttaggtaa ttaagaaaag 11160 attgcgtatg atgagttttt tttttggtat ttttgggatt gtttttaaaa ttagataagt 11220 gtttttattt tgatatttta ttaagatttt aatgaataga atgtcgtttg tttttagttt 11280 gttggttttt ttgcgaaggt ttagggtttt tttgtttgaa aagttatttt tttgtcgagg 11340 tttttgattt ttttttatta cggtagttat gtcgagggtt tatagagtta tttttttttt 11400 attttttttt cggtttttta agacgtattt gtattttcgg agatgttttt ttgttttttt 11460 gggttatttt ttttggtcgt tatttatttt gttgatttat tatttgtgta atagtttttt 11520 ttggaatttt taggtttttg ttatttattt tttgtagttt tcgttttgtt ttttttgttt 11580 tagttttttt ttttattatt tttttatttg ttggttttta tttttgttta tggtatattt 11640 ttgtgttata ttttgatggt tggataaagg ttgagtgaaa cgtatttatt tttttggtga 11700 ttggggtgtt tattaattag aagggattta aggttggcgt agtttttttt cgtattttgg 11760 ggtatcgttt tgtggttttt ttttgttgga gtttgtagtt ttttgttttt ttttttttaa 11820 attttttgag atggagtttc gttttgtcgt ttaggttgga gtgtagtggt gagattttag 11880 tttattgtaa ttttcgtttt tcgggtttaa ttaatttttt tgttttagtt ttttaagtag 11940 ttgggattat aggcgttcgt tattatgttt ggttaatttt ggtattttta gtagagacgg 12000 ggttttttta tattggtcgg gttggtttcg aatttttgat tttaggtgat aggttcgcgt 12060 cggtttttta aagtgttgag attacgggta tgagttatta ggttcggtcg ttgagattat 12120 ttttataagt tattaggttt ggttgtagtt ggtagttttt gattattggt ttcgttttac 12180 gtgatttgtg attttttttt tggttttttg gttttgtttt gtttatttgt ttattttttt 12240 tatgtatgcg gtttgtttat agggtatgta atggggttta attaggaaat ggaaatcgtt 12300 tgagtattta tttatttatt tatttattta tttatttatt tatttttttt aagataaggt 12360 tttattttgt tacgtaagtt gaagtgtagt ggtgtgatta tagtttatgg tagttttgaa 12420 tttttgagtt taagcgattt ttttttttta gttttttaag tagttcggat tataggtgta 12480 tattatatgt ttgtttaatt ttttttttta tttttgtaga gatagggttt tgttttgttg 12540 tttaggttgg ttttgaattt ttaattttaa gtaatttttt tgttttagtt ttttaaagta 12600 ttggagttat aggtatgtgt tattacgttt tgttaatttt tgtatttttt gtgtgtgtgt 12660 aaagataagg ttttattatg ttgtttaggt tggttttgta tttttgggtt tatgtgattt 12720 ttttgtttgg gttttttaaa gtgttgggat tataggcggg agttatagtg tttggtttat 12780 ttgagtattt agaatagaag gatttaaagg cggggaatta gttatataga tgatgggaga 12840 ggtgaaggtt agatagggaa tagagaggta attagtagga aattaaagtg gtgtgggttt 12900 atatagtttt ttaaaggtat ggatgtaatg atttatttag aatgagaaaa taaataatag 12960 taaattataa attataagta gttgttaaat attataaata ttattatatg tagaagagta 13020 ttagttaatt gttagttata tttttaaagt tttatttttt ttatattttt ggtattattt 13080 ttttaatatg atgattttgt aatatcgttt tttatttcga gaatagaaaa ttgattaggt 13140 tggatatagt ggttcgtgtt tgtaatttta gtattttggg aggttaaggt aggtggatta 13200 tttgaggtta ggagtttaag atcggttcgg gtagcgtggc gaaatttcgt ttttattaaa 13260 aatataaaaa ttagtagggt atggtggtat atatttgtag ttttagttat ttaggaggtt 13320 gaggtgggag gattgtttga gtttaggagg tcgaggttgt agtgagtcgt gattatgtta 13380 ttgtatttta gtttgggtga gagagtgaga ttatgtttta aaaaaaaaaa aaaaataata 13440 aaaaaaaata taggttgggc gtggtggttt acgtttgtaa ttttagtatt gtgggaggtt 13500 gagatgggcg gattatttga ggttaggagt ttgaaattag tttggttaat atggtgaaat 13560 tttattttta ttaaaaatat aaaaaattag ttaggtgtga tgacgtacgt ttgtaatttt 13620 agttatttgg gaggttgagg taggagaatg gtttgaattt aggaggtaga ggttgtagtg 13680 ggttaagatc gtgttattgt attttagttt gggtaataga gtgagatttt attttaaaaa 13740 taaataaata aataaagcga atgaattttt ttagttgatt aaattttgtt tttatttttg 13800 gtagttggga tgtatataaa agtggcggtt aatatggagt tggtggtgtt gttataattg 13860 ttttgtttaa gatatatagg aattttggta aattttgttt tttttttttt ttttaaatgt 13920 gatttttatt aagaaagaag taggaaaatg ggggagattt ttaattgtat atgaggtatt 13980 tgtgtatgta tttttgatta gagagatttt tttgttttga ttttatattg aaggaattga 14040 attttttgtt tataatttta tttttggtga tgggagtaat tttttataga tttgtttttg 14100 gattcgtgta ttttaaattt tgtttttttt tattgcgtac gttttttcgg cgttaggtat 14160 cgtaggatat gttcgtgttt tgtgattttt gattttgcgc ggtaggtgga attggaacgg 14220 tgagtggagc gagtattgtt ggaattcgtt tttatatcgg gatagcgagt agtaattgaa 14280 ttatatatgg aaataaatgg gaattatata aatataattc gattaaagtt aaattaaata 14340 tttttttagt ttaatttttt tttagtagga gtttttacgt ggtagtaagt tttcgttttt 14400 attttatata agagaaaatg tgacgggtag gaatttaaga ttggaaatga acggggacgt 14460 taattgattg tagggaaaat attttttatt ttgtaaattt tataaaaaat gtttgatttt 14520 gtggatatgt ggttagggtt ttttttagtg ttttgagagg gaattatgta ggtagaggga 14580 gggtttttag tattgtgggg gtgatttgga gattggtagt agggtgttat tattattttt 14640 aggtggggat gagagggagg aagttttgtg attagagttt aggggttaga gttatttgtt 14700 gggagtttaa ataaaggtgg gattttggta ggagttggaa ttatatagag gattattttt 14760 tttgttggag aagttgtttg aggtagagga ggtggagagt tttcgcgttt ttttttgttt 14820 ttatttttta ggtttttttt aagtttttcg ttggttgaat ttagtttaaa gttagtaggt 14880 ttggggattt ggatatttga gttagtagag gtcggcgttt tttttatata aaggagggta 14940 taagaagtgg gaggtacgga gggggattag gttaggattt atataggatg tgtaaatagg 15000 agtttttttt tttttttatt ttaaatggta tttgtagtcg gttttatttt tttgttgtta 15060 gataggaaga ggaattttgt tttcggtatt agttgttttt atcgtttttt attttacgga 15120 ggtttttttt ttttttggtt tttgtttgta attattggcg acgttgatgg attatatttt 15180 ttggggagtt tggttatgaa tatggttttt tatttgttgt ggattaaatt gtgttttttt 15240 ttttgaattt ttgcgttgaa gttttaattt ttaatgtagt tgtaattgaa gatagggttt 15300 ttagggaggt aattaaggtt aaatgaagtt atagggtagg attttaattt aataggattg 15360 atgtttttat aagaagaggg agagatatta gagatttttt tttttttttt atttgtaaat 15420 agaggaaaaa tgacggagga tatagtaggg aggtgggtat aagttaggaa gaggggtttc 15480 gtcgggaatt aattttgacg gtattttgat tcgggatttt gggtttttta aattgagaaa 15540 tatatgtttg ttgtttaagt tatttttttt atagtaattt ggatggtagt ttgagtttat 15600 taaggtatcg tttgtattag ttagggtttt ttagggagat agttaatagg agatggatgg 15660 atggatggat ggttagatag atagataagc ggatagagag agagagagat aggtagatat 15720 agatagatag gtagataaat ggttagatag ataagtagat agagagatag agatagatag 15780 atataaatag gtaaatagat aggtagataa atggatagat agatgataga tagttaggta 15840 ggtagataga tatagatagg tagatagata gatagataga tgataggttg ggtttagtga 15900 tttttatttg taataattag tatattggta ggttgaggtc ggtggattat ttgaggttag 15960 gagtttgaga ttagtttggt taatagggtg aaattttatt tttattaaaa atagaaaaat 16020 tagttgggcg tggtggtgta tgtttgtaat tttagttatt cgggaggttg aggtacgaga 16080 attatttgaa tttgggaggt ggaggttgta gtgagttgag attacgttat tgtattttag 16140 tttaggcgat aaagtgagat tttattttaa aaagaaaaaa aagatagata gatgaatgga 16200 tagatagtta gatagatgat agatggatga taggtagata gataattgat aaatagatat 16260 aaatgatcga tggataggta gatatagata tattgattag gtagatgata gatggataga 16320 tagaagatag atggtggatg ggtgggtaga taggtagata gatagttaga aagatagatg 16380 atagatagat aggaaggaat ttattagggg aattggttta tattattgtg gaggttaaga 16440 tgtattatag aaggtcgttc gtaagttgga ggtttaggaa agttagtatc gtggtttagt 16500 ttaagtttgt aggttttagg attgggaagt tgttgatgta atttttagtt taaggttaaa 16560 ggtttgagag tttggggaat tgttggagaa ttgggagttt taagtttaag ggtaggagag 16620 gaaggtattt tatttttagg agaaagaggg aatttatttt ttttttgttt ttttgttgtt 16680 tggtaatgga atggtgttat ttatattgag ggaggatttt tattatttag tttattaatt 16740 tatatgttta ttttttttag aaatattttt atagatatat ttagaagcga tgcgttatta 16800 gttatttttt aatttagtta aattgatatt tgtcgttagt tattatatag gtttagaaga 16860 atcgtggttg tatggtgatg gtttttattt cgtttaaaga agttgaagat gaattgttgg 16920 tataagttat cgttttttta ggtttttttt agtcgtttat ttttttaaaa atgtatttat 16980 tgagtatttg ttgtatgtta ggtgttgtga taagtattgg ggtatagtag tgagtaaata 17040 aggatttttg ttttttggag tttatatgta gtagaaggaa atagaattaa tgaatttatt 17100 agttttagaa attattaaaa taggattaag agttgtggtg agaattaaga taaggtgatt 17160 gtatagaaag tgattgatgg ttgttttgga atgagtggtg aggggttata gagatgatga 17220 tagttgagtt gagattggga agataggaag gagttagtag tgtaaggatt aggttggaag 17280 taagtttggt gtattttagg aatagtaagg aggttagagg ggttgtagta gagtaggcga 17340 ggaggaggag ggagacgtag gttaaagagg agtttggggt tagatggagg attttttttt 17400 taaagtttag ttattttttt tttaaaggag aatgtgttat ttttaaaagt tatatatgtt 17460 agtatagtgt ttggtttatt atatgttttt agtaggcggt gagtatggtt gtttttgtta 17520 ttattatatt ataattatta ggaataatgg agttattagg ttttgtattt atagtaatgt 17580 gagggagtta gtaagttttt ttggggaatt tatttttttt tattaagttt ataagagttt 17640 gataattagg ttaatgtagt gagagttata gttgtttagt gtattggatt ttttagttac 17700 gggttaggat atttttattt tagtagaaat ttttaagggg attggggagt gtgttgtgga 17760 tgtttttggg ttatttagat tttttgggga gtttttttta tcgtagttgt tgtagggagt 17820 ttagttgtag tgatgaattg cggtttagtt ttgtttatgg gaaaatttta tatgggagat 17880 gggacggttt tttgttggtt ttttcggttt taggttgttt ttataagtgt agggattttt 17940 atttgggtgt gtgaatgggg tttaggatgt tttaagggta tgtggagatg ggggttagtt 18000 gttttttttg atgtttttga attttttttt tttgtttttt tgtattttat tgttttttgg 18060 ttttttttat tttgggtgtt ttggaataat atgtaattta atatataggt tgattttatt 18120 attttgtttt gttttatttt attttatttt ggaaataaag gttttgttat ttagtttgga 18180 gtgtagcggt gtaattgtaa tttattgtag ttttgaattt ttgggtttaa gtgatttttt 18240 cgttttagtt ttttaaagtg ttgggattat aggtatgagt tgttgtgttt ggtttaggtt 18300 ggttttaaaa gttttttatt ttttttgtat tttgatgata tttatttttt ggagtaggtt 18360 tttagttatt ggtttcggat attttgtagt tattattggt tagttgtggt atgtgaagtt 18420 gaggtttagg agaagggtag ttttgtttaa ggttatacgg tttagtgtta atatttagat 18480 tttagtgttt ttattttttt tttggtcgtt tttattttta gtgtattttt ggaggtttaa 18540 gggagttaaa ggttaggttt tggttagtta agaatttaaa aaagttgttt ttgtgttttt 18600 ttgttaattt attattttat tatttttttc gataatgaat ttagtttgaa ttttagataa 18660 ataaggatta atttttagta taagtatatt ttataataga tttgggatat atttatgttt 18720 aaaaatgatt tattgtttgt tggttttagt agtttatgtt tataatttta gtgttttggg 18780 aggttatagt tggagaattg tttgagttta ggagtttaag gttatagtga gttatgatta 18840 tgttattgag ttttagtttg ggtgaagtag taagattttt atttttttaa aaaattgttg 18900 attgtttatt tgaaatttag gtttaattga gtattttgta ttttatatga gaattttata 18960 taggtgagat ttagagtttt aatgtttatt ggtaagtttt tgtagggagg ttttgtgggt 19020 ttttggttgg tattgatgtt ttgtgatgag tagggttatt tggtaaggtg gacgtttgtt 19080 gtttatgtag gtagagtaag gttttgggta ggtatgagtt gattttattt tttttagttt 19140 gggagttaga tattgttggt agtttgtcgt taagagaggg gttggttatt aagagagggg 19200 cggtttttat gggttttttt tggtttttgg ttttttttta gttttttttt tattttaaat 19260 agaggttaac ggtatcgtat tagaattagt gtgttgtttt ttttggttgg tattttgtag 19320 ttgggtagat tgtttttttt ttataggagt tggtggtgtt tttttcgttt tatagggagg 19380 atggttgaga tttttgattt tgatataggg tgttgttttt tttttgtttt gagatagagt 19440 tttggttttt ttatttaggt tggagtgtag tggtatgatg ttggtttatt gtagttttta 19500 ttttttgggt tttagtaatt tttttgtttt agttttttga gtagttgaga ttataggcgt 19560 gtattattat tgagaataat gttttttata gtgtttattt ttttgtagga gtaagttttt 19620 aaggtaagga ggttgttttt tttatggatg aataaattga ttttgattta tagttttacg 19680 tgttagtttt gagggtgggg aaaggttgtt ttgtgtttag gtagggggtg ggggtaaggt 19740 taggagggtt tggtgtttag tgtatttttt taggatataa ttttaggtag tagaggttaa 19800 ggatagaggg gaggagaaga gggaggtggt tattattttt ttattttagt tttttttgga 19860 gataagtttg agtattttag ttgtttatta agtttggaga taagtttgga atttaaattt 19920 ttgattttga tttagttttt tatagttttt gtgagtaaat tgagttttag aaaaagggag 19980 tgaagtttgt gtattttgga cgtttttatt ttaggtttaa atcgttttta ttttaggttt 20040 aaatcgtttt tattttagtt taaatcgttt ttattttagg tttaaagcgt ttttatttta 20100 gtttaaagcg tttttatttt aggtttaaag tgtttttatt ttaggtttaa agcgttttta 20160 ttttaggttt aaatcgtttt tattttagtt taaatcgttt ttattttagt ttaaattatt 20220 tttaatatag gtttaaatta tttttaattt aggtttaaag tatttttatt ttaggtttaa 20280 agtattttta ttttaggttt aaagtgttcg taatttaggt ttaaagcgtt tttattttag 20340 tttaaatcgt tttattttag gtttaaatcg tttttatttt aggtttaaat tatttttatt 20400 ttaggtttaa atcgttttta ttttaggttt aaagtgggaa ggagttatag ggaaataaac 20460 gggggaggta cggatgatta ggatgagggt ttttatgatt tatttttttt taggggttat 20520 tttaagagtt ttttaaattt ttattatttt ttaatagaga tggggttttg ttgtgttgtt 20580 taggttgatt tttaattttt agttttaagt tattttttta ttttagtttt ttaaattgtt 20640 gaggttatag gtgtgagtta ttgtatttgg ttttttttag gagttttaag aaaaaaaatg 20700 ggaatagatt tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgttttga 20760 gaaagagttt cgttttgtta tttaggttgg agtgtaatgg tacgatttcg gtttattgta 20820 attttcgttt ttcgggttta agtgtttttt ttgttttagt tttttgagta gttgggatta 20880 taaatatgta ggttgatttt gtatttttat tagagacggg gttttattat gttggttagg 20940 ttgatttcga atttcggatt ttagatgatt tgtttgtttt ggttttttaa agtgttggga 21000 ttataggttt gagttatcgt gttcggttag gaatagattt ttttttgtag atgatttttg 21060 ttattattga aaatggatgt ttatgtataa ttgaattgtt ataacgtttt attttaaaaa 21120 gttttttttt gagaaaatgt gatttttgat agaggagaga ttgtttaggt tttatttatt 21180 gttagtataa aggtagagta ggggtgtggc ggtgttattt ttttttgaga tagttttatt 21240 tttgttttgt ttaggggttt agaagtttgg tttattcgag tttatagagg ggtttggagt 21300 ggttgtttta tattataggt ggggtttgta aggatttgaa atgatttttg agaaggcggg 21360 tgtggtgggt gtattttaat tattaaagta ataataatga tatattaaat agtgtttgtt 21420 tagattttga gtgtttgttt aaatattttt attttgtgat ttgttagatt ttagtataat 21480 aatttaggta aaagaaaaaa tagttgggcg tggtggtttg tgtttgtaat tttagcgtga 21540 ggttaaggta ggaggattgt ttgagattag gagtttgaga ttagtttggg ttatttgaga 21600 ttttattttt gaaaataaat aaattaataa aagattttta tgttttatgt tttttttata 21660 tttaggtttt ttaaattata tgtattgggg aaagtttatt aagagaagtt tttggtcggg 21720 cgtggtggtt tacgtttgta attttagtat tttgggaggt taaggtggga ggattataag 21780 gttaggagtt cgagattagt ttggttaata tggtgaaatt ttatttttat taaaaatata 21840 aaaattagtc gggcgtggta gtgtatgttt gtaattttag ttacgtagga ggttgaggta 21900 ggagaattat ttgaatttgg gaggtagagg ttgtagtgag ttaagttggt gttattgtat 21960 tttagtttgg gcgatagaaa aagattttat ttttaaataa ataaataaag ggagagaagt 22020 ttttgggttt ttagatatat gggttagtgt ttatttttgt aaagttgttg tgtttaaaga 22080 ggggttgtat ttggtggaat tggggtaaaa gagtagggag ggtattgggt agttgatttg 22140 gtttttatta ttggaaaggg gttgtgttgt tggtgttttg agttggtttt ataaggaaga 22200 tattgtatag ggcgttttaa gtttgttttt tttgtttagg tttatttttt tttttttagg 22260 attagggagt ttcgttcgtt ttttgttttc ggtatttgtt ttttggtttg tgagtattgt 22320 attttttttt gtttggaacg tcggtttatg gtgggttttc ggatttttgt tttttgttgt 22380 tttttgttat atttcgttaa agtgtgtttt atttatttat tgttattatt ttttgaaata 22440 gagttttgtt ttgtcgttta ggttggagtg taatggtgtg atttcggttt attgtaattt 22500 tcgttttttg ggtttaagcg atttttttgt tttggttttt cgagtagttg ggattatagg 22560 cgaatgttat tacgttcggt taatttttgt atttttagta gagatggggt ttttttatgt 22620 tggttaggtt ggtttcgaat tgatttcggg tgattggttt acgttagttt tttaaattgt 22680 tgggattata ggcgtgagtt attatgtttg gttaattatt ataatattga tattataata 22740 atattatagt tagataacgg tgattaacgt ttgtaattcg aatattttgg gaggttgagg 22800 taggtagatt atttgaggtt agttcgagat tagtttggtt aacgtggtga aattttgttt 22860 ttatcgaata tataaaaatt agtcggagcg tgatggtagg tgtttgtaat tttagttatt 22920 tgggaggcgg aggttgcggt gaattgagat cgtgttattg tagtttaatt tgggtgatag 22980 agtaagattt tattttaaaa gtagtaataa taataataat aataataata ttatttattg 23040 agttttaatt ttgtgttagg tattgtgtta gtatttgcgt tatgtgattt tattgattcg 23100 gaataattta tgagtaagta ttatttttgt ttttaaggaa gttgagattt aggaaatgga 23160 agttattttt tagggtttat agtaagggtt tggcgaggtt tgcgtttaaa ttttgattat 23220 ttgattttag gtttttttgt tttttttgtt ttttaaaaat ttaaatattt ttatttggga 23280 tgattttaga tagttagatt ttaattgttt tttttttttt tgagtatgtt ttattttaaa 23340 attatataaa gataatttat tttttaattg gagttacgga atcgttagat gttttggaga 23400 tttttttagt tatttttttg ttggatttag atataggttt gaataattag gtttaaggag 23460 ttgaattgga gtcgttcgtg gttagaggtt tttttttggg aatagtagtg gcggtagcgg 23520 ttgcgttgag tttggtaatt tgtttaagag taggggatgt ttaggttgcg ttcgtttttt 23580 ttttatgaac ggtttgtttt gcgttttttt tgtgttaagg gttgttaggt attagatgtt 23640 tattttagga aattagaaaa ataaatagtg taaataaaat aaaaatttta tttaagaaat 23700 ttgagataga tgttgttttt tttatcgttt ttttattttt atgttgggtt tggagagagt 23760 gggttagtat gttttttacg gataagaggt tttggggtat ttaatttgga tggaattttt 23820 tttatttttt ttttgtttgg tgttaggggg tagaaggtag gggtggtgtt tatttggttt 23880 agggaggagg atagggtagt ttttgtcgtc ggtatttttt gtagagatgt tttagttaga 23940 agtgatttta tttttaggaa cgtgtgtttt gttttttgtt gggcggtttt tttttatttt 24000 ttattgtttt tatagtgggg tgtgttagat ttatgggtag agttttggtt tatttttagt 24060 ttcggatagt agaatgtttt agtagtgtat tgatggtgtg tgcgtgggga tgtgtggaat 24120 aggggatagt gatttcgtgt gcgttatatg tagtgcggtt tttagtcggg tgtgtgaagg 24180 gggtgtttat ggttatcgtg gaagtgagtt tagttggggt tggagggttt aggtttattg 24240 tatgttattt agtagttttg ggagtggggt ttattttttt tttcgttttt tttttttttt 24300 ggttttgggt agtttatcgg agttgtattt tgggttattt tttttggttt taaggaggtt 24360 gttatttttg ggaggtagat gttggttttt ttatttttgt tttttggaga tttgcgtcga 24420 ggtttgtttt tttgtttgga gggattggtt aggaattttt gggttttttt ggtggggttt 24480 ttgttgttta gtagtgagta gagtgagtgg gtattaagag gaggatgttg ggtgaggtta 24540 cggatatggt tggggtaggt tgggggtgtt ggaggtgaat ttcgtagttg tgcgattttg 24600 ggtagtttgt ttagttttgg gtttcgtttt tttttttatg aaatggggcg ggagtatttg 24660 tttgttgggg ttgtgggttg ggtgaatcgg agttaaggta tagtttatag tttgtcgtta 24720 gattttcgta agtagaagtg ggtgtttttg tttagcgttt ttcggttttt tttttaaggt 24780 ttagttttgt ttttattttt tttatgaagt ttttttggtt attttaggag ttacgattta 24840 tatttttttt ggagttttgt gttatacgta ttttttacgg tgttgttttt tttggaggat 24900 gggtttaatt aaaattgggg tttatttggg ggtttttttt agtattagag aagtttaggt 24960 ttagtagaga tgggtatttt gttaatatta gtttcgcgaa ggatatattg tgtttatttt 25020 gttgttagtt gttgagtttg gtgttttgta gttatggaat atgtgtatag gtttgggttg 25080 ttggatacga aggttagatg ggtagtttat tttgttttcg ttttgagttt ttagaaataa 25140 gttggttgta tttattttta tttggttata gtttaggagt ggggttgtgg aatggatgga 25200 aggaaggatg agtgggtggg tgggggggtg ggtgggtggg tggatggatg gatggatgat 25260 gggtggatgg gttgatggat gggtggatta ggtggatagg tgaatggatt ggtgggtggg 25320 tgggtgggtg aagggttgaa taggtgggtt gggtggatgg gtggatggat gtgtggaggg 25380 gtggtggggt ggatggggtt tatgggtgaa tggatggatg gatgggtgaa tggagtaaat 25440 gagtgggtgg atggatggat ggatgttgta agagtttttt tggagggttt tagggaggaa 25500 ttggtatttt tgattagtag ttagtatggt gattagatat agggaggtgt ttgggtttgt 25560 ttgatttttt attttattgt tggtgggatt gggttggtta tgtgtttttg aagttttttg 25620 aagggtggtt gtatggtatt gtttagggga tatttttaga gtgtcgtgtt ttatagtaat 25680 agggtggtcg tttgtgtttt tagggtcgtt ttttttggta gtttttcggg tttgtttggt 25740 ttagtatttt agtaaatttt ttcgagttag gatttgtttg ttatgagttt ttttaataag 25800 tagttttagg ttaaggtttg tgtgtgggta gagggagcgt atgtcgcggg aggttgtatt 25860 aatttgaggt tttgtttttg tttttttttg gggtaaaagg taaaaatagt ttgttttatt 25920 ttatttttaa atttagttcg gttgtattta gttttgggag tgaagggggt tgggttagga 25980 ttgttcgtga gttgtagatt ttggtgtagg gaaattttga tttataagac gggtggatat 26040 ggaggaagga ggagatttcg tttagtagag atacgtttgg gtgtagttta gtttggagtt 26100 tgatggacgt gggtttattt gtgtgtaatt tttatttatt gtgtggttat agggaagtga 26160 tattttgtgg agatttagat tttttatttg taaaataggg gtagtagggt ttgggggagg 26220 atgtgtgtga aggtttggtt tagggttttt ttagtagtta gatagtagtg gttgttattt 26280 ttttagcgtt tagggttatt tgggggagta gggtttttgt ttttagatgg gtttcgtttt 26340 tggttttgga atttatagta ggagtaaagg cgaggatatt tttggtgtta attatttatt 26400 cggagggaga gcgttagtgg ttttgtgtga tttttgtttt ttgtttttgt ttttaggagg 26460 tacgcggatt tttagtggtc ggtttcggag gtttggtgat tttagtggtt taggtaggtg 26520 gttcgtttcg ttttggtttt atttagttta tgggtgtgtt tgtgttgggg tttttttatt 26580 ttggtttggg atttgttttt ttatttggtt tttttggatg agtggggtta tttgtttatt 26640 ttttagggag acgtagtttt tgacggtttt ggatttaggt ggtttttagg tttgtcgacg 26700 ttgttttgtt ggagatgatt tttgtggggg taggggtagt tatttttagg tttagggagt 26760 aagttcgtgt gtgcgggata gaggagagaa taggagatag atagggttgg atgatttggt 26820 ttgagatgtt gaggggatag atgtgttatg gataggtggt tttggtcgtg agtttttcgg 26880 tgttggttta gtatttgtgg gttttttgta attttgtagg atggaagatg ttttaggata 26940 gagtagatac gttcggtgtt atttaggagg aaataagtgg gtttttggta gtggttattg 27000 tgttattttt tgtgtttttt ttatgtgttt ggaaattttt tatattaatt agtagggaag 27060 ggaaatagat gtatttatta gagttttggg gttggtcgtt taggatacga gttatagttt 27120 ataggtttga agggatttta ttaatattgg gtgtagtttg ggtaagggag tgggatagag 27180 aggttagggt tttgttttta gtttttgttt tttagggttg agtttgcgcg ttattttttt 27240 tttattgggt gtttttgatt ttttttgttt gattttagtg tggttatgtt agtgtttttg 27300 tttttgggag tttacgttgt ttttggttgt tatttttagc ggttaggttg ggataggtgt 27360 ttatttagtg gtttttttat ttggagagga tgatgggtta tagtaatgaa tggatttatt 27420 ttttttagga gacgaggagt tttgagaaga gtagagatgg cgtggttatt tgtgtatatg 27480 tgttgggggt taattgggtg ttagattttt ggttgttatt atggtggtag ataggtaggg 27540 attgtgtttt tatgaattag ttattttaga ggagataaag ttattaaagg atacggattc 27600 ggagttaaat ttatataaat agagcgtttg tggattaggg ttgtttttag aataaggtga 27660 gatagtcgtt ttgttaggat aaggcgttta cgggggtaag ggtatgtgtt tatttggagt 27720 cgttattttt atgttttaga ttagtttcgt ttaatagaat tttttgtgat ggtgggtttg 27780 ttttatatat ttgtatttcg ttattttgta tggtagtcgt ttagtcgttt gggtttattg 27840 tatatttaaa gtataaatgt ttacgtttat tttatttatt tatttatttg tatagaatta 27900 tttatttatt ttaaatggat ttttatttat atttacgtgt ggttagtggt tatgaaattg 27960 aatagtttta gattatattg gtatttgaga ttttagaatt ttagatttaa agtttgtttt 28020 tgattttgag tttgtttttg tggggatagt atagacgttt tttaagtttg ttttttagag 28080 gtggatgtag tgttcgtgga ttgtgtatta ttaggtttgg atagtggaga gggtggtttt 28140 ttatagggag tgggagtgga ggggatgtcg tgtttatatt gagtgtatgt gaggtttttt 28200 gtagtatagg atgggattgt atgtgggaag aggggggtga tgttttggtt ggaggttttt 28260 gggtagttgt atgatttagc gttgtggtta agaggggttt cgtttatcgt agttatgttg 28320 ggtattaatt attggatagt ttagtcgttg ttgtgttttt ggggagtttt ttttcggttt 28380 cgtatttgat ttgttttttt attttttttt tttttattgg ttagtttttg gtggaatggg 28440 tggggagggt tttttagttt ttgtgggggt tgtattttgg gaatttggta ttttgggttg 28500 tatggatata gtttttttcg gcggttgttt ttttttgttt agattggttg gttttgtgtt 28560 gttagtattt ggtagttacg attatagttt agtttggaag tttaaggtat aatttgttga 28620 attttaaagt tgtaagttgg tgatttgggt ttgcgtggga ttgtttgttg atatacgggg 28680 tttttttttt gtgggttttt gtgggttttg gttcgagata tttttttttt atttttttgg 28740 tttttttttt tttttttgtt ttttttttgt taagattttg gtttaggtag gagtttattt 28800 ttagacgttt tagtattttc ggttttttta tttgatattt tttagacgat tgtttgttat 28860 tttatttttt tagtttagtt tttttgtaga tttatatttg gttaattttt tatgtttggg 28920 atttttgttt tttttagaag gacgaaggtt tttttcgagg ttgtgtttgg gattgggtta 28980 gggatgatat ttttggtaaa agtttaaatg atattatgat taacgttttg gttagtttat 29040 atattttttt tttttttaaa aaaaaaatgg aatttttaga gttataaaat aaaaatgtaa 29100 agaataaggt aataaaatat ttgtgtattt attatttcgt ttaagaagtg agatattgta 29160 ggtgtagtcg tagttttggg tgattttttt tattttagtt ttatttttgt tgcggtgttc 29220 gtttttttgg attgggattt ggtttcgggt aggtatattt gtgttgggta gtggtgtgtt 29280 tgagaagttt aggttttttt tttttttttt ttgagataga gtttcgtttt atcgtttagg 29340 ttggagtgta gtggtattat ttcggtttat tgtaattttt gttttttggg tttaagcgat 29400 ttttttgttt tagttttttt agtagttagg attataggta ttcgttatta tgtttggtta 29460 attttttttg tatttttagt agatataggg ttttattatg ttggttaggt tggttttata 29520 tttttgattt taggtgattt atttgttttg gttttttaaa gtgttgggat tataggtgtg 29580 agttatcgta ttcggtttgg tttttttttg tatacggtta ttagtatcgt gtgattgagt 29640 agtttaggtt tgtttttttt tgaatgtcgt tattagtatt atatttttgg tgttttattg 29700 gagttagtgg ttgttttgtt tgtgtttata acgtgacggc gtggagattt attcgtgtag 29760 atttacgaag ttttggttta tttattttgg tagttagcga gtgttttttt gtgtggggag 29820 gtagagtttg ttcgtttcgt ggtttattgg tgatatcgtc gaaggttttt tttgttatta 29880 gtgttgtcgg gaacgtgtgt ttttttaggt ggatttggtt gggttgtgga gatgcgtttt 29940 ttagtttttt tagatgttat tattacgttt tttcgagtgg ttttttggta ggttttttta 30000 tgttcgttta ttttttgtgt tttaggtagt cgtttttttg attgagcgtt tagcggattt 30060 ttgttttgtt ttttacggtg tacggagtat tttattttag tggtgtttga gttttttttt 30120 ttttggtttt tagatttcgg ttgggatttt tggagttaat ttttttgttt gatatttcgt 30180 gtcgttaggt tttgtttttt tattttttaa tatttttggg gtgtgtggtt ttttttttag 30240 tgtttttatt attttttttg ttttaggttg aatcgtgttt tttataaatt tatgtttatt 30300 aaaaatttta gaatgtgatt tgggagttgg agatggggtt tttgtagatg taagtagtta 30360 aggattttga gatgaggtta ttttggatta gggtgggttt taaatttaat aattggtgtt 30420 tttaaaagaa gtagagaggt tatagatata tcggggagag ttacgtgaag gtaggagtag 30480 atgatggagt gacgtagttt taggttaggg agcgtttggg aagaggtaag gaaggatttt 30540 ttttttattt tattttagag tttttttagg gagtgtggtt ttgttgatat tttgattttg 30600 gatttttggt ttttagtatg ggagagaatt cgtttttatt tttttaagtt ttatagttgt 30660 ggtttattat ggtagttata ggatattgat gtatttttta tttggtcgtt gtggatggac 30720 gatttcgttc gtaggaagtt ttttttaagt attgtaggtg tttttgtttt tataggggac 30780 gtttgtataa gtaggtgtga aaaaagggtt ttgtgggggt aaggtttggg ttggtgttcg 30840 ttgttttttt ttattttatg ttagttttta tgtttttttc ggtaggagtg tttggtttta 30900 tttggtgaat tagagttaaa tttttttgat aattggttgt tatttattta attgttatta 30960 tttttaggag atagaaaatg ttagaagggt ggggtttgtg tagtgttttt tcgttatttt 31020 tttagggtat cgtgttacgt tgttttaatg tatagagtag ttgtttaaag tgtgtcggac 31080 gaataggtgt tttatgttta gttatgtaga taaaagtgtg ttacgtggag ggagttggtc 31140 gtggaagaga ttattagtat tttggttgtt cgaggatttt gtttttgggt ttttgtaggt 31200 atttttagtt tattattttt ttttttattt atagttattt attttttttt tatttttttg 31260 atattagttt tgttatttat ttaggtttgt aagtaggaaa ttttagagtt gattttgatt 31320 tttgtttttt tagtattttt aggttttaat aggttgttaa gattttatta attcgttttt 31380 tgtatattga tttttggata ggttgtttcg gttacggtta tgttttggtt gggtttttat 31440 tatttttttt tggattagta ggtgttattt tttttatttt tgttttgttg tggttttttt 31500 ttttttacgg ttaatattta gaggacgatt attatttttt tttttgtgtg ttggggatcg 31560 ggtgatagga tttttttatt cgattatttt tattagattt gggtcgggtt tttttattta 31620 tagagttttt agttttcgtt tttaaagttt cgagggtgga ttcgtgttgt cgtttagttt 31680 ggttttgata tcgtttttta gtttggagtt ttttgttttt gcgtttttgg ttttgagtgt 31740 tcgggttttt tttggatggg ttgttatttg ttttttggaa agtagggttt ttatgttttt 31800 ggatttttta gttgatttag tgattttggg ttattttgtt atattttttt tattagtttg 31860 gttttggtta tttttgtgtt ttttatagtt tcggattaga gttacggcgg gatgtttttt 31920 tggtgcgtgg taggtagtta ggaaatattg ttggattgat tttgatagga gatgtttggg 31980 agaattgttt aaaaaattag tttaaaatgt aaatattggt ttttttttgc gttggttaaa 32040 gagtagtatt ttttcgtttg tttttcgggt aagaaattga tggcgaatgt aatgttttta 32100 gggaggagaa gaaggtgata aaaagggttt gtataacggg gtatacgtta ggtatttgtg 32160 attatttaag tttaaattat aatataaatg cgaaattttt tgttttggta gtttttttat 32220 attgtaagcg tttattgtta tatgtggttg ttatattgat tacggtagat atagaatatt 32280 gatattattg cggagagttt tatggggggg cgttggttta gattattttt acgttggatt 32340 tataaattta ttgtttattt agtgaacggt tattgggtat ttattgagta agtaggatga 32400 aagatattcg ttttcggggg agtttttcgt tggttgtaga gaagtttaaa tttaggggat 32460 ttggggtaaa ttttgtaagg gtttttggtt tttgtatttt tagatttttt tcgttttgta 32520 ggggtagtcg ggggtttttt ttaggaatgg agcgttagtt ttagtttttg ttaggttata 32580 gtttagatgg ttggttgagt acgagtatgt gagagtggaa ttgggtttaa tcgggttgtt 32640 ttttttcgtt gttttggttt ttttttacgt tgatttggaa ggatttttaa agtaataggt 32700 ttgtttaggc ggtttgtatt agtaaatttt gtagcggttt taagggtaga gatagttgga 32760 ttgtatttat ttaggaatag ttaaagtttg aggtataata aaaagtggag aaagatttta 32820 gagaggaatg tagttggttt tagtttggga attcgttttg tttgggaggt tgtaggcggg 32880 ttaggttggg gttagtttgg agggttttgg ttggttttgt tggtaggtat agtagtaggg 32940 ttagtaggag ggagtttagg acggagtttt tttattttta atttagggaa gtaaatttta 33000 gtggttgagt ttgaggatga gtaggaaatg aatggaaaag tttttttttt tttttttttt 33060 tttttaggta gggttttttt ttgtttttta ggttggagtg tagtggtata attatagttt 33120 attgtagttt taatttgtta ggtttaaggg atttttttgt tttagttttt taagtagttg 33180 ggattatagt tgtgcgttat tatgattggt taatttttaa aagaaatgtt tttaggttag 33240 gtatggtgat ttatgtttgt aattttagta tttttggagt cgaggtggga ggattatttg 33300 agtttaggtg ttttagatta gtttgggtaa tatgacgaga tttcgttttg attaaaaata 33360 taaaaagtta gttgggcgtg gtggtatagt tttgtagttt tagttattcg ggaagttgag 33420 gttgtagtga gttgtgatta cgttattgtt ttttagtttg ggtaaaggga gtaaggtttt 33480 gttttaaaaa aaaaaatttt tttttttttt gaggtggagt tttgttttgt tgtttaggtt 33540 ggagtgtagt ggtatgattt tggtttattg taatttttgt tttttaggtt taagtgattt 33600 ttttgtttta gttttttaag tagttgggat tataggtatg agttattgtg tttggatttt 33660 tttttttttt tttttttttt gtagagatgg gattttttta tgttgtttag gttggttttg 33720 aatttttggt tttaagtgat ttttttattt tggtttttta aagtgttgga attataggtg 33780 tgagttatta tatttagtag gaaaagttat tttttaaagc gagaggttgt gcgtttttta 33840 tagtttggcg tttattagta tggaggattt attggaacgt gtgttaggtg aggggatatg 33900 gaagatggta gtaaattcga gtttagagta ttagaaagta tgtttttagt taaagatgcg 33960 ttttttttat tttcgcgtag tatttttttt tagtgtgtat ttttggagta aggtggggtc 34020 gattttacga agattttttt tcgaaggttt ttgttgttta tattagtgtt atttggatcg 34080 tttgtttttt tttttggatg gttggattag ttttagggtt ttttggtttg gtgtggggag 34140 tatagtttat tttggggaat gtttggtatg tgtttttttt ttattgggta ttaggggatg 34200 aagttgtgtt tcgtggaagg ggatagaggc gttggtgttt aggatggtgt atttggggcg 34260 gttgaattgg atttggtttt tattgggttt ttgtggagtt tagattgttg tgagaagggg 34320 tggggaaagg taggtgattc gtatttttta tttttgtttt atatgggaat aggggtttat 34380 tttgtatata tatttagttt ggagtatgaa tttttatgaa gaggaaaatt tttattaggt 34440 tttgatgtta ggattgttcg tgagggtcgg gtcgtgtttt ggggtaagga taggagtgga 34500 gggggtaatt agggaaggtt ttttaatgga ggaggtattt gatagtattt tgaaaaagaa 34560 gtagttttta ggttaagtta gagattgaag aatgattatt taattttttt tttttttttt 34620 tgagatggaa tttcgcgttg tcgtttaggt tggagtgtag tggcgtgatt taggtttatt 34680 gtaattttta ttttttaggt ttaagtaatt tttttgtttt agttttttga atagttggga 34740 ttataggtat gcgttattat gtttagttaa tttttgtatt tttagtagag acggggtttt 34800 attatgttgg ttaggttggt ttggaatttt tgattttgtg atttatttgt ttcggttttt 34860 taaagtgttg ggattatagg tatgagttat tgtattcggt tacgattatt taattttttt 34920 ttataagatg ttttttggtt gacgtaaagt aggttgagtg agtgtgatat tttttttttg 34980 tttgtgggtt tcggtttttt tagagttcgg ttagtgttat tggagataaa gtggttttcg 35040 tttttttttt tcgttttgtt aggtttagtt tgtgtcgttg agttttattt tgtaattaag 35100 aggagttgtg aattagtgat gttgatgtcg tagaaaagtg gttaggggtt tatggggggt 35160 gaaggatagg gatgtcgttt tgagaattgt ttggaagggg tttttgggta atagtgttta 35220 ttttagggtg tgggtaggtt ggggtggttg ggagttgggt ttataggttg gtataattag 35280 agttttttaa agtcgtgggt ttgagggttt tgtttttttg ggatagtaat ttttggttta 35340 atttgggaaa aggtgggtta aattaagttc ggttttttta ttgtaggatt atttagtgcg 35400 tttagtatgt aaatgtgttt ttgaatttaa gataggatta tagaaatttt tttagtgttt 35460 ttttggaggg agggatcgcg ggggatttat cgtaggggtt tgggtttgta ttggtttggt 35520 gaagtgtttt tttagtgttt atattatgcg cggtgagagg ttggttttcg ttttttttat 35580 tttttgttgg ttttatttta ttatttttgt attcgttttt tagtcggttt atgattaatt 35640 tttgtttttt tagagttaat cggtgttgtt aggtttttta ttttaagtga tttttcgttt 35700 gggttaaaat gtttggattt ttaggtacgg aggggagatg gattttaggt taaattatgt 35760 tgggtaaaat tgagggttaa ggttgtgttt agtaagtgtt ttagttttgg tcgttaaatt 35820 tatagtgtgt atagcgtgta ggaggtggtt gggtgaatga atttagttat agttcggttt 35880 tttattcggg gttgttttta agtttttatc gttagttagg ttgggttaga gtttcgtggg 35940 gtttttttgg gtttttttgt tttatagtag gagttcgtat ggagagtttc gagtgaggtt 36000 aatgggtttt tttttttttt tttttttttt tttttaattt gagatagggt tttatttttt 36060 ttatttagtt agggtgtagt agtgtaatta tagtttatag tagtttcgaa tttttggttt 36120 taagtaattt tttcgtcgta gttttttaaa gtgttgagat tataggtacg tgttattttg 36180 tttagttggg gtttttgttt tttatttttt tttttgtttt taaatttaat ataaagaaag 36240 atattatatt tataattaga aaaattaata aggaatatta ttttaaaatt ggaaaaggga 36300 ttaaagaaat aaattaagaa atttttgcga tttttgttta tcggagttag tggttgttag 36360 tggttggttt aatataatgt tttaggaaga aatagaataa tagaaagtaa ttttagtgag 36420 ttgagttttg gtttcgtttg tggcgttgta ttagtttttt gtagttgttg taacgagtgg 36480 ttataagttg gttgggttat aataacgttt agttattttt ttatagtttt gtaggttata 36540 tattcgagat tagggttatt aggttgaaat tagggtgttt attgggtata gttttttgga 36600 ggttttaggg taggggtttt tagtttcgtg tgttttatta ggaattggtt tgtatagtag 36660 gaggtgagtg attggtaagc gagcgaagtt ttatttgtat ttatagttat tttttattgt 36720 tcgtattatt gtttaagttt tgttttttgt ttgattagtt atggtattgg atttttatag 36780 gagagtgaat cgtattgtga acggtatatg tgagggattt aggttgcgtg ttttttatga 36840 gaatttgatg tttgatgatt tgttatcgtt ttttattatt attagatggg atcgtttggt 36900 tgtaggaaaa taagtttagg gttttaattg attttatatt atggtgagtt gtataattat 36960 tttattatat attataataa taatagaaat aaagtgtata attaatataa cgtgtttgtg 37020 gtcgggtgta gtggtttata tttgtaattt tagagtgaaa ttttgtttta aaaaataaaa 37080 aataaaggtt aggtatagtg gtttatgttt gtaattttag tattttggga ggttaaggtt 37140 ggcggattac gaggttagga gtttaagatt agtttggtta atatggtgaa atttcgtttt 37200 tattaaaaat ataaaaatta gtcggatacg gtggtaggcg tttgtagttt tagttttttg 37260 ggaggttgag gtagaagaat tgtttgaatt taggtggcgg aggttgtagt gaattgagat 37320 agtgttattg tattttagtt tgggtggtag agcgagattt tgttttaata aaataaaata 37380 aaataaaata ataaatataa tatatttgaa ttattttaaa attatttttt tattttttgg 37440 tttgtggaaa aattgttttt tttgaaatcg attttaggtg ttaaaaaggt tgggggttat 37500 tgtttttatc gtttgttttt ttgagttttt ggtggttgtg ggtgtttttt ggtttgtggt 37560 tgtatggttt ttatttttaa tattagtatt tatagatttt ttcgggtttt atttttattt 37620 ggttattttt gtttgtgtta aatttttttt tgttttcgtt ttgtatgagt atcgagattg 37680 tttttaggga ttatttagat tatttagggt gttttcgtta tagtaagatt tgtaattgaa 37740 ttatagatgt aaaaattttt gttttaaata aggttttatt tgtaggttta gggattagga 37800 tatgttattt ttggggttat tatttagttt tttttcgtga ttatgatttt tttttttttt 37860 tttagttttt tatttcggtt gagatgttgt ttttattttt tttattgttt ggttgtttgt 37920 ggggttgttt tttaggtttt ttgggaggag gtggttgttt gatgtttttt agaaggttgg 37980 gaatggtttt ttttattttt taggaagatg ttttttttgt taaggagatt gtatttgggg 38040 ttttatttta ggtagagagc ggacgggatt gtggtttgaa gtggtatttt agggtttttg 38100 gttttgttat ttagtcgagg gttgtgtatg ggttttattt ggttataggt aatttatttg 38160 gttttgtggg gtagggattg taaatttaga ggtttgcggg gtgtgtcgag gtagaggggt 38220 gtaaatattg taaatttgtt gggggttttg gggagtagta tagattgaaa agtgttttgt 38280 ttgaagagta gaattgtttt atattagttt tgtgcggtta ggtaggaagg ttttcgtggt 38340 gcggttacgc gttttttttt ttttaataga agttgatagt ttggagtttt tagagagatt 38400 gtttgagttt ttagttttgg tataaatata tatttttttt aaataggttt gggttaatag 38460 aattagtttt cgtgtttcgg gtttgaatga atttttgagg tgaagtttaa agatagagag 38520 gatgtttttg atttttattt tagggattta tattgtaaat ttttatttgt tttgttgagt 38580 ttttggtttt agtatggatt ttgattatgt gttggtgggg attttttagg taagtaagta 38640 gtttttgagg atttcggatg aatagtgggg aatagtattg attttttagt ggggtttcga 38700 gttttcggag aggaagattc gttttttttt aggggacggt tagagattta ttgatttatg 38760 cgtgtgtggt aggaattttt taggaagttt tcgtttcgtt cgtttttttt gtttgggcgg 38820 ggacggtaat tgtttttgtt attgtagatt aatgggacgg aggggggtga ttttttaggg 38880 ttttttttgg gtaggtgttt cggaattttt ttttagtacg ttggtttggg gtacggtcgt 38940 tttttttgtt tagttacgtt ggggtatagg gtgaagaagg gttggggtta gtttaggata 39000 gaggaaggcg aggtaggtac gtaggaattg ggttttttaa atttttaagt ttaaggaaat 39060 cgtagtatcg cgggataggg aaaatgaaag attttggaag tcgttaggaa tttgattttg 39120 tgagttggtt tttaagagtt taagttaagt atttttaagt ggatattaaa aaggagtagt 39180 aagtttcggg gcggcggggg ttggaggagg tggagagagg aggttgtcgg aagtcgtatt 39240 cgggattttt gtagttatcg attagatcgg gcggtcggga ttttgggatt ttcgtaggta 39300 gattcggtgg tttgtcggat ttttcggggt ttatttcggg tttttttttt tgttttttat 39360 ttttggattt tttttttttg tttttttttt tttttcgttt tgaagagata atgttatttt 39420 agtttggagt ataaatatat gattagtata tggaaatgtg gtaattcgga tgtattcgtg 39480 attgtaatag attgaagaaa ttagattaga taaagagtgt ttttagagga ggaggaggag 39540 gaggaggagg ttgagagagg gagggcgacg ggggtgagaa aggggaggtc gtttttgagc 39600 gggacgtcgg gattttcgtc gttgttaaat atattcgtag gaatggagag ggatcggatt 39660 ttaggtacgt agatagtttt ttttttatcg gtcgtttttt attgttttgg attcggggtt 39720 ttatttatgt ttgggggaat aagtatgtaa agggcgtttt tgtttatttt ttatagaaat 39780 attttttttt tttttgacgg ttttaagttc gtgggatgaa tttcgtttta gaagttaagt 39840 ttttttgagt ttggttttta tttaaattcg gttttttttt tttttggtta tttttttttt 39900 attttttagt gtgttatttt tgtatgttat ggttattgtt aatgttgagg ttgttggcgt 39960 cgaaattttg ggagggtgtg ggggatttgt ttttttggtt cgggtttggg gcggcggcgt 40020 ttggatttgg ttggtggttg gtttgtttat tgtgtggttt gttttttgtt tttagttaaa 40080 gtttgttttt aaggttgttt cggtttttta tttaaaatag tatttttgtg tttttttggt 40140 agttgattat agagggggaa gttttcggcg tttagaggag tttggcgtgt gtgtgtacgt 40200 gtgtgtgtat gtgtgtgcgt gtgtttattt acgttggtag tttttttgtc gtaggtatag 40260 atttattagg gcgtgaatag gtaaatgaag agaaaggggg tttttttgtt tttagtttat 40320 tttagttttt taggtttttt tttttaggtt tagttttttt ggttttttta tttatatgcg 40380 gtgtcgtggt tgttatttta cgtggttagc gtcgttatcg gtaattagta gtgatgatag 40440 tttttgtcgt ttatgtcgtt ttttgagttt agcgttggga gatatggggt ggttgagtta 40500 agttttaggt tttgggtatt ttgaagtgat ttacgggtta tggagcggga ggtcgttaag 40560 agtgttaatt tttacgtgtt ttgggttttg gtttgttggt tgttattatg tgtgtgttgg 40620 ggggtttttg agaggtttga gagagggagg tttatttcgg tggttttttt ttaggacgtg 40680 tggttttttt tattattgtt tttagggtta tatttttttt tttttttttt tttgagacgg 40740 agtttggttt tgttgtttag gttggagtgt agtggcgcga ttttagttta ttgtaagttt 40800 cgttttttta gtttatgtta tttttttgtt ttagtttttt aagtagttgg gattataggc 40860 gttcgttata tttttttgta tttttagtag agatggggtt ttatcgtgtt aattaggatg 40920 gtttcgattt tttgatttcg tgattcgttc gttttagttt tttaaagtgt tgggattata 40980 ggcgtgagtt acggcgttcg gttttagggt tatattttga ttgttacgtt gggattggtg 41040 gagcgggtgt gtgttgtgtc gttgagtata tttagtcggg tatagtaggc ggattttagg 41100 agggggttag gggagacggt agaaggtttg ggtggtagtg aaattgtatt ttatttgttt 41160 gagttcgggg gtttaggttc gttgggacgg gtgggtgtgg agtttagcgt tttgtttttc 41220 gtttagtagg agtcgtaggg tagggagcgt tgagagggat tttcgttagg tttgtatagt 41280 ggagtcgttt tcggagtgat tattttatta ggtagtttgg gtagattata gtgggttttt 41340 tgttttttgg gttattagtt ttaggaggac gttattttat tcgtttggtt ggtaggggtt 41400 tcggggagtt tcgggttcgg tttttatttt atagatgatt tagtcgaggt ttagatgggt 41460 gattagtagg ggatttgaga gttgagtaga gaggcgtggg tttgggggtg gtgttttttg 41520 gggagttgga agtgatggta tttttttagg tttataaaat acgggttttt tatgaattga 41580 ataaaatatt ttttgaaagt agttagtgtt gtgttttaga gattattttg atttttgttg 41640 tttttggttg aggatagtat agttagggat gaagcgggga ttttttttcg ggttgtgttt 41700 tgatgaaaga tgttttttat aaaattttat tcggatgtgt ttttatgtaa gaaaacgtat 41760 atttttagaa atttagttgt aaattggttg tttttcgaat gaatacgata gtttcggagt 41820 tgtttttttt aatgaggttt tcgttttggg taaattttag cgttggtttt taattgttat 41880 tgaattttcg tatagttttt ggggaagtga tttttttttt gtttttgttg ggtggttttg 41940 agtaagttat ttggtagttt tgggtcgtag tttcgttatt tgtaaggtga ggggtgggag 42000 cggtacggtt tttaggtagc gtttttattt tttgcgggtt tttgcgcgtg ttttgagttt 42060 tgtgggcgtt ttttttttta ttgaggggtt tttttttttt gtagggtatg gtttacgtcg 42120 cgttgttagg ttgtaagtta ttgcgagagt tgttttgatt tttaagtatg ttttggtttg 42180 aggaggagtt atggggagga cgttgtgttt gtgtgataga ggtttgttcg gtagatgtcg 42240 gttcgttgat ttttagacgt ggttgtgggt gttttatgtt ttattgggtt ggcgtgtgag 42300 gcgtgtttag tttaggttgt tttatagttg tttaggaagg gtttgtggga gggggtggtt 42360 ttattttggt gagtttacgg tggtttgtta gttttaggga aggtttagga gttttaagat 42420 ttgttttttt gttttttttt cggtagtgtt tggtttcggt ttggtttgtg aacgggggtt 42480 tgggtatttt ttcgtttttt ttgggggttg tggttttttt ttgggaaggt gttggagggt 42540 ttgttagtag ggtcggtatg agttatggag tggtgattgg tcgttgaggt atggaaggtt 42600 atttttttta gttaagggtc ggagtttttt ttttgttttg gaacggtttt gtggttttta 42660 taaattaagt agttttattt tgttttaaga gtttgtattt tagtagggag agagttttta 42720 agaagggaat tttttattgg ggagttttgt tgggttggga ggttaggaat aggttacgag 42780 ggagggttgt aggtagggga agtggtcgtt tgtgtatggt tatgaatgta ggttcggggt 42840 tttggagggg gtttggttac gttgtcgttg gacgtttgtt tttattaggg tttatttgat 42900 gtagtacggt atagggtaaa gtttagtttt ttttacgggg tttttgggtt attagtgggc 42960 ggggaatcga ggttttttgg agggcggtgt tttagttttt attttttttt tttgtttttc 43020 gttgtgttgt tttcgatggt ttttgttatt ttttgggagt ttttattttt ggacgttcgg 43080 tgtttgttcg gttttaattt ttttagtttt gtttttttat tttcgaggtg agaggtttgg 43140 tttgacgcgt tttgtattcg ttttttgttt agtttcgtgg gaattttggt ttttgtagtg 43200 gttttttggg gttgttatta ttaagtgtta taaattgggt ggtttaaaat attagatatt 43260 ttttttttcg tcgttttgga ggttagaagt tcgaaattac ggtattagta ggtttggttt 43320 ttttcggagg tttcgagggg gagtttgttt ttcgtttttg gtagtttttg gcggttttcg 43380 aaatttttgg cgttttttgg ttcgtggtta tattattcga tttttgtttt cgttgttacg 43440 gggttttttt ttgtgtttta aatttttttt tgtttgtttt ttatacggat agtttttttc 43500 ggatttaggg tttattgggt aatttaaaat ggttttattt taagattttt aattttataa 43560 cgtttgtaaa gatttttttt ttaaataggt tatgtttata ggttttgggg tggatgtaaa 43620 ttttaggggt tattttttat ttttttgttg ttttcgtgtg tttggatgta tagtatggtt 43680 ttatgtttta gattttttgt tggatttttt tggttttttg gggtggtttt tggttttttt 43740 tattcgtttt tgtgtttttg gtgaggtgtc ggggtcgggt ttagtttttg taggaatttt 43800 ggggatagta tggagtcggt aattttttat taggcgtttt tttatttgtt tagagtttat 43860 ggttgtgagg ggtttttttt tgtggttttg atttgtaatt ttttagtggt tagtgatgtt 43920 gagtattttt tcgtgtttat tgtttatttg tatatatttt tgtagaaatg tttgtttaag 43980 ttttttattt gtgtttgatt tggatgattg ttgttgttga gtgttaggag atttgtagat 44040 taatatttag atattaattt tatatttgat ttatgatttg ttgttatttt atggattgtt 44100 ttttttttac gttgttagtg ttttttgata tgtaattttt tttttttttt ttgagatgga 44160 gtttgatttt gttgtttagg ttggagtgta gtggtatgat tttggtttat tgtaattttc 44220 gtttttttgg ttttagcgat ttttttgttt tagttttttg agtagttggg attataggta 44280 ttcgttatta tatttagtta atttttgtat ttttagtaga gacggggttt tattgtgttg 44340 attaagttgg tttcgaattt ttgattttaa gtaatttatt cgtttcggtt ttttaaagtg 44400 tcggagttat aggcgtgagt tatcgtattt aggttgatat gtaaatattt taaattttta 44460 tgacgtttta ttttatttat ttgttttttt gttgtttgtg tttttggcgt tatatttaag 44520 aaattattgt taaatgtaac gttaggaagt tttttttttg tgtttttttt taagagtttt 44580 gtggttttag tttttgagtt taggtttttg atgtaagttg agttgatttt tgtatgtggt 44640 gtaagggttg gtttagtttt atgttttggg tttttgattt attttttttt tttttttacg 44700 tttagttggt ttcgttgggt ggcggggagg agtggggaag tttcgggttg ggtttgtatt 44760 cgattatttt tttttaggtt agttagggag ttttagtttt tgtttaggat ttggttggac 44820 gtgtttttta tcgggaaagt ttgggtcgtt tttttaggtt gatggtaggg ttagttcggg 44880 gcgttttgag gtttgttttg cggatatgtt ttttgtttta ggtggtgtgg ttgttcggtt 44940 tgcgtgtgag attagttgtt tgtgttttag gttatggagg ttgagtgttt ttagtttgtt 45000 tttttgttcg gttttttttt tggggaagtt tttgtagttt attttttgtt ttcgtttttg 45060 ttatttgtgt ttttgtttgt tttttgtttg gaggtggtta tttttggggt tattttttat 45120 gatttggata taagttttta ttttgaagtt attatttaaa tttttgtgtt ttaaattttt 45180 tttatttatt atatgggttt ttattgtgat taatttagta gttgatgaag ttttttttgg 45240 ggttttttta gtaacgggga gttggttttt tcggaggttt ggtttttttt taagtggaag 45300 tggggcgtga gggtgttagt ttttttttgt tgtttggtgt tttaggttgg tttgttattt 45360 ttggaagtat ttgttatttt tatatagtat tttatattta ttttttcgtt ttttattttt 45420 ttttttaagg ggttattttt gttttttttt ttatttaatt ttatttatgt ggttcgttta 45480 gtaatttttg atttttaata tgataaaata aatttttttt gtcggttatt tatttattta 45540 tttagtattg ggtgtttttt gtggatttgg cgttggggtt tcgtggagga taaagttaga 45600 tatagttttt gtttttatgg gattgtataa gtgtaagatt atattagtaa acgtgaaata 45660 taggaagtga taggtgtgat aaaggggatt agtggtagga tagaatttgc ggttcgtagg 45720 attaggttag gagggttgtt tcggggggat attttcgggt tgagcgtaga aggatgaggg 45780 gagtaaatta ggtttaaatt tagtaggtag aggcgatcgt tgtaggtaat cggtaatgtg 45840 tttaaaggtt ttggggcgcg gggggttgag gtcggtagta cggtaggaag taagattggg 45900 gttgaaagag attgattgtt atgttgtgaa atatatattt ggtttttatt tttatttttt 45960 ggtatataat ttttaaaatt tttggaattt ttaaagtgat gtttttttgg atgtttatga 46020 ttgatagatt agttggtagt tttaggatgg tttttaggga agattaggta gaattataag 46080 gtttagtatt atttcgtaat ttttaggtag gggagagggg ttgaaggtta agtagattat 46140 tagcggttaa tgattgaatt aattatgttt tcgtaatgag gttttcgtga atatttagaa 46200 ggatggggtt tcgggagttt ttggatggat gagtatgtgg aggtttttgg agggtggagc 46260 gtttggggag tatatggaag ttttgcgttt tttttttata ttttgtttta tatatttttt 46320 tttttgtatt ttttgtaata ttttttataa taaattagta aattttatga gttttaggaa 46380 tatgtgtaaa agaaaaaaaa aagaataaat tatagttgtt gtagtaagtt aattttatta 46440 gtattggttt ttatttgtcg attttatttt tggtaatgtt tttttttttt gggtttttgg 46500 gattttttcg gttttattat tttttttgta gtggtttcgt tggttgttgt ttttaggtta 46560 gtttattttt attcggtttg tttttattag gggttgaggt ttttttgttt attttagttt 46620 tttggttcgt tttttgtttt gggtattttt ttatttcgaa cggttagagt ttttgaagtc 46680 gttcgttgtg tgttttcgtt tggttttatg tatttcgtac ggtgtttttt agggtttttt 46740 attggtaagg gtattggtat agattttggg gttgttttgg tttaagttta ttttgatttg 46800 gagtttgagg gtttttgagg gggttttgaa ggttagggta ggtaaggttg gtatgttttg 46860 ggtagtgggg gttgggtatg ggaggggatc gtgggtgggg agattttttt taattagcgg 46920 tttacgtttg gagattgatt tgggttttag gttacgtttt gaaattggga tagagagtgg 46980 cgtagatttt agttcggaga ttttttttgt ttgtggacgt ttttatattt ttattcgtgg 47040 agttattttt tttttttttt ttttaaatgg ggaaattttg atttgaatat tgaataaata 47100 atatattttc gaaattagcg aagaggtatt ggttttgaaa ttttgttatg aaagtttgaa 47160 aatgtttttt ggatcgattt gttggaatag acgggtgtga tggggttgcg gggttttagg 47220 tggtaggagg cgttttcgtg tttagggtat ttcgatgttt agagtttttt cgtgtttagt 47280 gtgtttttgt atttagggta tttttatgtt tagggtgttt tcgtgtttag tgtgtttttg 47340 tatttagggt atttttatgt ttagggtttt ttcgtgttta gggtgttttt gtatttagag 47400 tatttttatg tttagggtgt tttcgtattt agggtgtttt cgtttttagg gcgttttgtg 47460 tttagggtgt tttcgtgttt agtgtgtttt tgtatttagg gcgtttttat gtttagggtg 47520 tttttatgtt taggtattgt ttttttttat ttttttaatt tttttttatt aataggtgtt 47580 agttgtgaaa tgtttgttgt gtgtgttttt tggttgagtt tattttgtgt ttttaagttt 47640 ttgttagata taggtaggtt gttttagttt ttttggtaaa tgttttgttg ttgttgtttg 47700 atacggggtt ttatttcgtt atttaggttg gagtgtagtg gcgttatttc gttttattgt 47760 aattttcgtt ttttaggttt aagcgatttt tttgttttag ttttttaaat agttgggatg 47820 ataggcgttc gttattatgt ttggttaatt tttgtatttt tagtagagat ggggttttat 47880 tatgttggtt aggttggttt cgattttttg attttaagtg atttatttag tttggttttt 47940 taaagtgttg ggattatagg tatgagttat cgtgtttggt tcgtttggtg aatgtttatt 48000 gaggtttatt atgtgtagtt ttttttttag gtgtttggtt tgtaatgagg agtaataaag 48060 atatagtcgt tggtcgtttg ttatttaata gttggaattg agaggtagtt tataaatgag 48120 taaatttata ggtggtttta gatgaggatt gtgaagaagt taagaatagg ttgttggggg 48180 tgtatatttg tgtgtgtggc gaggggatta atggaagttt tttttgagtg gtgatattga 48240 gttgaagttg taatgattag aaggatttag ttaggttaaa atttaaggga agagtaattt 48300 ggtaaaggaa atagtaggtg tgaaggttcg aggttggagt ttggggaagg tgggagtggt 48360 tggagtgtgt ttttagagac gggttatggt gatattaatg cgataggtag ggttaggtcg 48420 tgtcgggttt tggaggtttt ggtgagggtt tgattttatt tttattatgg tgggatttta 48480 gtgttttgtg gttgttgaga atggttaggg gtaggtaggg aggtttgtta gggaggaggt 48540 tgttgtaggt tttgtagttg gagagggagg attaggattt ttttagagag gaagttggag 48600 agggaggatt tttttgattg ttggatggat ttatttgttt ggttgttttc gttagtattt 48660 agtagaggtt attggatgtt gataggtggt cggttttgtt tagttttgta ttgttttgtg 48720 ttgttttggt ggttgtcggt tttaggagga gcgtttttgg tgtttgagtt tagtggtttt 48780 ggttgtggtt tggtatattt ggtcgtgggt gaggttaagg tggtttggat tttgggaagg 48840 ttgggtattt ggtagtttta aggtaggagt tggggtgttg gaggaggaag tacgtttatt 48900 tttcgttttt ttttgtttcg tgggatgttg agtttttggg tagggatatg gtgagttttg 48960 gtgtgatgta tttaatattt gttggtgttt ttatttttaa gtaggaattt tggtgtttgg 49020 tgtttgagga ttgttgttta tcgttttatt attttttagg ttttttttta gtttttgatt 49080 cggggtaagg tttagatatt tagaatattt ttggttggtt tttggagttg gggtgaggta 49140 gaattttttt tttatattta tagtattagt taaggtttcg gggtttggat attatttttg 49200 ggaggggtga gtaggataag tgaggttttt agatttgggg tggtttcgga ttggttaggt 49260 aggtgggtgg gggttgtagt ttatgttttc gttttaggta atatagtcga gttgtagttt 49320 tcgttttatt tttagttggg gttttttgtg tttatttttt gttttttttt tttttttcgg 49380 aatggggggt ggatatttta agattagttt tttagttatt ttttttgttt tttgtttttt 49440 ttttttcggg atagattttt gtgatcgttg ggtgtttttg atgttttgtt ttttttgcgt 49500 tttgtgtcgt gggtgagaga gggtttcggg gggatttttt ttttttggag tatttgttgt 49560 ttcgggtgtt tttgggggcg ggtttttatt ttatattgtg gagttggtgt aggaaggaag 49620 gtgtcgggag ttagttttaa tttacgtgtt ggttgtggtt tttaaggtgt ggatggtagg 49680 aggtggtgag atagggattt attgattatg ggattgatat ttttttatgt tgatgtgggt 49740 tttgagttat aattttatta gtttttgagt tttggcgttg tttttggcga tggcgtggat 49800 ttagttaggt tttcgggtag ttttttttgg attttttttt cgtttttttt tgggtagtgt 49860 ttttgtttat ttggaaagga tgggtaggat ttggagataa tagggattta aagaagtcgg 49920 gagtgggggt atttgtgtag tttattttgt agaatagata atttggttaa agtttaaagt 49980 ttgttgttag gagtttcgtt tgttttttag agagtatatg gtttgattat tacggggatt 50040 gggggagagg tataggtatg tttgttcggt agtagaaggg aatttcgggt ttgggttttt 50100 ttattttgtg gcgttgtttt tttttagagt tgtattgttt tttttattgt ttttgtttgg 50160 ttttagtgtt tatgtggttt gtggttttta gtttgggttt ggtttttcgt aatttatttt 50220 gtttagtttt atatagtttg tttttttagt tgggaatcgg agtttatttg gagttttagg 50280 tagtagattc gatgtagtga tgtagggttg ttagttatgt tagtaggttt tgttgtttat 50340 agagggatgg gtattgttgt tgataataat taaagaatta cggttttagg ttgggtatag 50400 tggtttatat ttgtaatttt agaattttgg gaggtcgagg taggagaatt aattgaattt 50460 aggagtttta gattaggttg ggtaatatag taaggttttg tttttataaa aaataaaaaa 50520 taataataat aataaaaatt atagttttag aatgattgat tttagtatgt ttataaagtt 50580 aagggttttt agtgttttgg gtttatgtta ttgcgttaga gggagagagg aagaggttgg 50640 ggtgatgggt attggggttt atgttttttt tggaatgggt ggttttggat tgtgtttgtg 50700 tgatatgttt gtcgagcggg ggcggtgttt attgaggatt ggatgttgag gtgtgggtgg 50760 ggggaggtta tgaagtattg ggtatttttc gtgtattagt gtttcgagat tgtagagagg 50820 ggattcgttt agtttgggta gggaggcggg tggtagcgag gaaggggaga ggaattcggg 50880 tgtagaaagt ttttttttta gtaggtggcg tcgtaagttt tcgagagttt agtttttgcg 50940 gggtttgtat ttttattgaa tttgtgggta gaggttgttt gggtgtagtt ttcgttaatt 51000 gtgattgttt attgcgggcg aggggaagtg gagtgtagag aatgtatcgg agggtagatg 51060 attagttttc gtataggtac gggggtgttt tttttttcgt ataggtacgg ggggttcgag 51120 tttttggggt ttttgtttta attgggcggg gaaagggagg gttggaagtt gagttagggg 51180 gaaagggggt ggttttttgt tatttttttt attttatttt ttttattttt ggttgatagg 51240 ttttaatttt ttttatattt ttttaatttt ttgtcgtaaa attttttaaa tatagaaaag 51300 atgaaagagg gttgagtgtg gtggtttatg attgtaattt tagtattttg ggaggttgag 51360 gtaggaggat tatttgagtt taggagttta agattagttc gggtaatata gtgagatttt 51420 atttttataa aggatataaa aaattagtta ggtatggtgg tgtaggtttg gagttttagt 51480 tattcggaag gttgaggtga gaggattgtt tgaatttggg aggttgaggt tgtagtgagt 51540 tgggattgtg ttaatgtatt ttagtttggg cgatagaata aaattttgtt ttaaaaataa 51600 aataaaataa aattataaaa aagaaattat gaaagatttt aaagtaaata tttatgtatt 51660 tattatttag attttatagt aattattttg ttgtttgttt tattataaat ttttttggtt 51720 attagtattt acgttggttt tgatgtattt aaaataagtt gtagaaatta gtatataata 51780 ttttgttaat attttagttt gtattttatt aattagagtt cggtatttgt ttgtgattat 51840 ttttgttttt ttttgaagta aaatgtatat attttgagat gtataggtgt gaaacgtttc 51900 gttttttgaa ttttaataaa ggtatttacg tgtattttag tttgattaga atatagaata 51960 ttattattat tttagtaagt tttttatgtt tttttaggtg tattatagtt tttatttttt 52020 ttagggtaat tataattgtg tttttttttt attacgaaat aattttgtta gtttgagtgt 52080 tttttagagt tatttatgtt gttgtaggtg ttagcgattt gttttgtttt attgttgagt 52140 aacgtttatt gtgtgaatat tttgtgggtt tttagttatt tttttgttga aagatttttg 52200 gttgttttta tttggaggtt tttatgagta aatttgttac gttggttttt tttgtataag 52260 tttttttgtg tatatgggcg tttatttatt ttgtagaaat atttagagta ggtatagggt 52320 aggtatatat ttagttttat aagaaattgt tagatttttt tttaaagtgg tttttttatt 52380 ttatattttt attagtaatg gatacgagtt ttagttgttt tatattttgg ttaatatttg 52440 gtgttgttat tttgtgaaat tttagttatt ttggtgggcg tgtagtggta ttattttatt 52500 atggttttaa tttgttttgg tttgatgatt aatgcggttg agtatatttt tatgattggt 52560 tttttatata tttttttttt gtgaaatgtt tttttaaatt tgttgtttat tttaaaattg 52620 ggttgtttga tttttttttt tggatattga ttttttgtta gatacgtgtt ttataaatat 52680 tttattttag tttgtggttt gtttgtttat tttttttttt tttttaagaa taaggtttcg 52740 ttgtattgtt taagtaggtt tgaaattttt gggtttaagt tgtttttttg tttttgtttt 52800 tttaagagtc ggttttatag gtatgagtta ttatgttcgg tttgtttatt tttttagtgg 52860 tattttttaa taagtaaaag tgtgttattt taatttttat gaagtttaat ttaataaatt 52920 tttttttttg tggttttttt tttgtgtttt ttgtaagaaa tttttgttta ttttgttaaa 52980 ttgtaaagat atttatgttt ttttttagaa ggtttagagt tatatagttt ttatgaatta 53040 atttttgtat atggtgtgag gtagagggtt agggtttatt ttgttgtcgt tttatgtgtt 53100 tatttagttg ttttaaattt tatttttttt taaagttttt attttgtatt tttttggtga 53160 tttatgaggt cgtataattt tttaagattt ttgttggtta tttacgtatt tttttttgta 53220 aaattatttg tttacgtttt attttttttt aaaattatgt tgttttaaga tcgagtgatt 53280 tttgaagttt ttattttata atgtttgaaa gaatgaatat tttgtttttt agttataggt 53340 ttttgttttt tgttttgtag ttgtatagtg gggtaagatt tgggttttgt tttgttgttg 53400 ttttgttgtt tttttatttg attgtttttt tatgggtttt atttaaaaaa aaaattggtc 53460 gggtatagtg gtttacgttt gtaattttag tattttggga ggtcgaggcg ggtagattac 53520 gaggttagga gattaagatt attttggtta atacggtgaa attttatttt tattaaaaat 53580 ataaaaaatt agtcgggcgt ggtggcgggc gtttgtagtt ttagataatc gggaggtcga 53640 ggtaggaaaa tggtgtgaat ttgggaggcg gagtttgtag tgagtcgaga ttgtattatt 53700 gtattttagt ttaggtgata gagtaagatt ttgttttaaa aaaaaaaaaa aaaaaaaatg 53760 ttgttttata tgttttttat atattttgga tataagtttt ttattagata tatgtattat 53820 aagttttttt ttttatattg tttttttttt tttggttttt ttaatgatgt tatttaatga 53880 gtaagagtat tttgttttta taaagtttaa tttattaatt ttttttagtt tcgatttatg 53940 atttttgtga tttatggagg aaatttttgt ttatattaag gttaaaagaa gtttttttat 54000 tttttagaaa ttttatagtt gtatatttta tgattttttt tattttttaa ttttttaaat 54060 ttttatattt tttaatttat tatagtcgtt aggatgttgt atgatttatt ttaaattagt 54120 ttttgtattt ggtttgaggt tagggttaat ttttgttttt ttatatttat atttagtttt 54180 agtatcgttt gttgaaaaga tatattttat tttattgaat tatttgatat ttttgttaaa 54240 aattattgat tgtatatgtg gttttatatt agtatatgta cgtatatata tgtaggtttt 54300 gtgttgattg tatgtgtggt tttatattag tatatgtacg tatatatata ttggttttat 54360 gttgattgta tatgtggttt tgtattagta tatatatatt agttttatat tgattgtata 54420 tgtggttttg tattagtata tgtatatata tatatgtagg ttttatgttg attgtatatg 54480 tggttttata ttagtatatg tatatttata tatgtaggtt ttgtgttgat tgtatatgtg 54540 gttttgtatt agtatatgta tatatatata tataggtttc gtgttgattg tatatgtggt 54600 tttgtattag tatatgtata tatatatatg taggttttat gttgattgta tatgtggttt 54660 tgtattagta tatgtatata tatatatata ggtttcgtgt tgattgtata tgtggttttg 54720 tattagtata tgtatatata tatatgtagg ttttatgttg attgtatatg tggttttgta 54780 ttagtatatg tatatatata tatgtaggtt ttatgttgat tgtatatgta gttttatatt 54840 agtatatgta tatatatata tgtaggtttt atgttgattg tatatgtagt tttatattag 54900 tatatgtata tatatatatg taggttttat gttgattgta tatgtggttt tgtattagta 54960 tatgtatata tatatatgta ggttttatgt tgattgtata tgtggttttg tattagtata 55020 tgtatatata tatatgtagg ttttatgttg attgtatatg tggttttgta ttagtatatg 55080 tatatatata tatgtaggtt ttatgttgat tgtatatgtg gttttgtatt agtatatgta 55140 tatatatata tgtaggtttt atgttgattg tatatatata tgtggttttg tattagtata 55200 tgtatatata tatatgtagg tttcgtgttg attgtatatg tggttttgta ttagtatatg 55260 tatatatata tatgtaggtt ttatgttgat tgtatatgtg gttttatatt agtatatgta 55320 ttgtatatat gtaggtttta tgttgattgt atatgtggtt ttatattagt atatgtattg 55380 tatatatgta ggttttgtgt tgagatatta ttgtgttttt ttgatatttt gtttattttt 55440 ttgttgatgt tatattttga ttaatgtggt tttatagtaa gttttaatat aaagtttttt 55500 aaatatttaa aatattattt tgaatatttt aggttttttg agttttttta taaatttaag 55560 aagtagtttg ttgatgttta taaaaatgta gtgtgaattt tggttgagat tgtgttgaat 55620 ttgtagatta attaaggaag aattggtatt ttaataatat tgagtttttt gtatagatgg 55680 tatattttcg ttttaaaggt ttttttgtat tttttttatt tttttattga aaaaaaattt 55740 ttatagaatt atattgtttt gtagttttta agaaaaagat tttgtatgtt atttgttaaa 55800 tttattttta agaattttat ttttggtatt attttaagtt gaaatagatt ttaaatttta 55860 tttttaatta tttgttgtta gtatgtaaaa atataataga tttttgtatg taaattttat 55920 attttatgat tttttttaaa gttatttatt attttggtaa tggttttgta ggttttttag 55980 gatttaaata tatagtttta tttttttttg attttgatgt tttgtttttt ttttttgttt 56040 tattgtattg gttagagttg ttagtttagt attgaatagt agtgattagt ggatattttt 56100 gtttgtgtta aatttataat gttaatttta gatttgttat atatgatttt tgttagattg 56160 aggaaatttt tttttatttt taatttgttg aaatttttta atatgaatgg gtatgatttt 56220 agtaaatgtt ttttttgtat ttatggaaat gattattgtt ttgtttttta ttcgtttaat 56280 aggataaatt ataatgattg atttttgttt ttcgtttttt tttttttttt ttttaaagaa 56340 atagagtttt atttttgttt aggttgtagt atagtggtgt tatcgtagtt tattgtagtt 56400 tgaatttttg gatttaagta atttttttat tttagttttt taagtagtag ggattatagg 56460 tatatgttat tatgttaagt taatttttaa tttttaaaat tttttgtata gatggggttt 56520 tattgtgttg tttaggttgg tttgtaattt ttgagtttaa gtaatatttt tatttttgtt 56580 ttttaaagtg ttgagattat aggtgtgagt tattgtgtag gtttgatttt ttaatattga 56640 attaattttg tatttttgga agaagtttaa tttgtttatg agatattatt ttttttatat 56700 attgttaaat ttgatttgtt tagtttttaa ggatttttgc gtgttgattt atgagggata 56760 ttggtgtggt attttttttg tttgttagtt tgtttcggta atgtttttgt tagttttatt 56820 ttggttttat aaaattagtt tggaagtgtt tttttttttt tgttttttgt gtttttataa 56880 ggttgatgtt gttttttttt taaatgtttg atagaattta ttaagaaaat cgtttggatt 56940 tagaattttt tattaggaaa ggtgattgtt tgtttttaat tataaattta atttaatgta 57000 tagaaagagt tatttaggtt tttttatttt tttttgtttt atttttggta agttgtattt 57060 tgaaggaatt tgtttttttt aggtaagttg ttgaatttat ttatttaaag ttgttcgtaa 57120 tataagtata tttagggttt gtttttagat ttcggtaata aagtaaatat tgtaataaag 57180 tacgttatat aaattttttg gttttttagt atatataaaa gttatgttta ggttaggtat 57240 ggtggtttat gtttgtaatt ttagtttttt gggaggttaa ggtgggcgga ttatttgagg 57300 ttaggagttt gagaatagtt tggttaatat ggtgaaattt tatttttatt agaaatataa 57360 aaattagttg ggtgtggtgg tatatgtttg tagttttagt tgtttgggag gttgaggtgg 57420 gagaattgtt cgaatttggg aggtggaggt tgcggtgagt tgagattata ttattgtatt 57480 ttagattggg tgatagggcg agattttatt ttaaaaaaaa aagaaaaaag ttatgtttat 57540 attatattat agtttattaa agtgtataag attattatgt ttttttgtta aaaaatgtta 57600 ataattattt gagtttttag taagttataa tttttttttt ggtagaaggt ttgttttaat 57660 gttgatggtt gttgattagg tggtggttgt tgaaagttga aggtagttgt ggtagtagtt 57720 tttttgtttt tttttttttt tttttttttt ttgagataga gttttgtttt attgtttagg 57780 ttggagtgta gtggtacgat tttagtttat tgtaattttt gtttttcggg tttaagtaat 57840 ttttttgttt tagtttttcg agtagttggg attataggtg tttgttatta cgtttggtta 57900 atttttgtat ttttagtaga gatagggttt tattttgttg gttaggttgg ttttaaattt 57960 ttgattttag gtgatttatt tgttttggtt ttttaaagtg ttgggattat aggcgtgagt 58020 tattgtattt ggtcggtagt tttttaattg aagtttttga tatgggttga tttttttttt 58080 tatgaaagat ttttttgtgg tacgtattat gtttgatagt attttattta taatagagtt 58140 ttttttaaaa ttagagttaa tttttttaat tttggttacg gattgattaa ataagttgat 58200 gtaatatttt aaattttttg ttgttatttt aataatgttt atagtatttt cgtttggagt 58260 agattttatt tttaggaatt attttgtttg tttatttata agaagtaatt ttttatttgt 58320 ttaagtttga ttatgggatt gtagtaattt agttttattt ttaggtttta tttttaattt 58380 tagttttttg ttatttttat tatatttgta gtgatttttt ttgttgaagt tttaaatcgt 58440 ttatttatga gggttggaat taattttttt taaatttttg ttaatgttga tattttaatt 58500 tttttttgtg aattataagt gtttttaatg gtatttagaa tggggaattt tttttagaag 58560 gtttttaatt tattttgttt agatttatta gaggaattat taattatggt agatattgtt 58620 ttataaaata tattttttaa ataataagat ttgaaaatta aatttatttt ttttttatgg 58680 gttgtagaat gggtgttata ttagtaggta tgaaaataat atttattttt atatatattt 58740 tcgttagagt ttttgggtta taaggtgtat tgttaatgag taataatatt ttgaaaggat 58800 tttttttttt tgagtagtag gttttaatga tttttttttt tttttgatgg agtttcgttg 58860 tgttatttag aatggaatgc ggtggtatga tttcggttta ttgtaatttt tgtttttcgg 58920 gtttaagtga tttttgtgtt ttagtttttt gagtagttgg gattataggt atatattatt 58980 atgtttggtt agtttttgta ttttttgtag aaatagggtt ttattatgtt ggttaggttg 59040 gtttcgaatt tttgatttta ggtgatttat ttgttttagt tttttaaagt attgggatta 59100 taggtatgag ttattgtatc gggttttatt tgtttttttt ttgttgttgt tttttaattg 59160 agatagagtt tcgttttgtt gtttagattg gagtgtagta gcgttatttt agtttatcgt 59220 agttttcgtt ttttaggttt aagtgatttt tttgttttag ttttttgagt agttgggatt 59280 gtaggtgtgt attattatgt ttggttaatt tttgtatttt taatagagat gaggttttat 59340 tattatgttg gttaggttgg ttttgaattt ttgaatttag gtgatttgtt tgttttggtt 59400 ttttaaaatg ttgggattat agttgtgagt tatcgtgttt ggtttttttt tgtttttttg 59460 ttttttttta aattgagata gagttttttt ttgttgttta ggttggagta tagtggtacg 59520 atttcggttt attgtaattt tcgttttttg ggtttaagcg gtttttttgt tttagttttt 59580 taagtagttg gaattatagg cgtgtgatat tatgtttgaa taatttttgt atttttagta 59640 gagatgcggt tttattatgt tggttaggtt ggtttcgaat ttttgatttt aagtgatttt 59700 ttcgttttag tttttaaaag tgttgggatt ataggcgtga gttgtcgtat taggttttaa 59760 tgggttttta atatttagta aattatgttg taaatagatg tgttgttaag tagggtttgt 59820 tattttattt ttgaagtata gatagaatag atttggtaga atttttaagg gttttaggat 59880 ttttggaacg gttaatgagt attggtttta atttacggtt aatagttgcg ttagtttttt 59940 atgagagtta gtttgttttt tgaagtttta aagataggta ttgatttttt ttttttagtt 60000 atgaaaattt tagatgatat ttttttttag tagaaggtgg gatatttatg ttgaaatttt 60060 gttgtttagt gtagttattt ttattagtgt tttgagttag attttttggg taatttgttg 60120 tcgttttttt attagtattt gttgttttat tttgtatttt tatattatag agatggtttt 60180 tttttttaaa ttttatgatt tgatttttgt tagttttaaa tttttttttt ttagtttttt 60240 tatttttttt agtttttata ttattgaaga gagttagggt tttgttttgg attaggtttt 60300 tgtttaaggg aatgttgtgg ttgatttgat tttttattta gattatttaa atttttttta 60360 tattagtatt aaggttgttt tgtttttttt ttttttatgt gtgtattgga atcgtatttt 60420 taattttttt taataatttt tttttggtat ttataatttg gttagttatt tggtataaga 60480 gattttattt ttgtttgttt tggttttcga tacgtttttt ttatttagtt taattatttt 60540 tagtttttga tttaaagtga gagacgggtg attttttttt ttatttgaat atttagaggt 60600 tattgtaggg ttattaattg gtttaatttt aatattgttg agttttaggg aatagggatg 60660 tttgagtaga gggagagaga gcggggaata gttagttagt ggagtagtta gaatatataa 60720 cgtttattga ataagtttat tgttttattt ggatgtggtt cgttatgttt taaaaataat 60780 tgtaataatg gtattgaaga ttattgatta ttgggcgcgg tggtttatgt ttgtaatttt 60840 agtattttgg gaggtcgagg taggtggatt atttgaggtt aggagtttga gattagtttg 60900 gttaatatgg tgaaatttcg tttttattaa aaatattaaa attagttagg cgtggtggcg 60960 ggtgtttgta gttttagtta ttggggaagt tggggtagaa gagtcgtttg aatttgggag 61020 gtggaggttg tagtgagtcg agattatatt attgtatttt attgtatttt agtttgggta 61080 atagagcgag attttatttt aaaaaaaaaa aaaaagggtc gggcgtagtg gtttacgttt 61140 gtaattttag tattttggga ggtcgaggcg ggtagattat gaggttaggg gattgagatt 61200 attttggtta atacgatgaa atttcgtttt tattaaagat acgaaaaaaa tagtcgggcg 61260 tggtggtggg tgtttgtagt tttagttatt cgggaggttg aggtaggaga atggcgtgaa 61320 ttcgggaggc ggagtttgta gtgagtcgag atcgcgtcgt tgtattttag atagagtaag 61380 attttgtttt aaaaaaaaaa aaataaagaa agaaaaaaga aaaaagagat tatagattat 61440 tatagtagat ataataataa tgaaaaagtt tgaattattt taagaattat taaattttta 61500 tatagagata tagtgttaat atgttgttgg aaaaatggtg ttagtagatt tatttgatgt 61560 agggttgtta cgaattttta atttgtaaaa agtgtagtat ttgtgaagta taatgaaatg 61620 aggtgtgttt gtgttttttg ttattgtaat gtcggtagga ttcgtaagga aaatatttta 61680 ttttttttat tgtgatttta tgttcgttat ttttttttta ttagtagttt ggttaggagg 61740 ttattaattt agattttttt aaagaattag tattggattt tttttttttg gtgtttattt 61800 ttttgagttt ttttgttatt tttattattt ttttttttgt atttgtttta gcgtattagt 61860 tagggtttag ttaggaaata aaaattatat cggtaatttg aatagtaatt tgtaatataa 61920 agtgttttta attgtaagag gtagttaatt attaaaggga ttataaaggg gtgatattgt 61980 gatataagaa agatgtattt gggttgggtt cggtgtagtg gtttatgttt gtaattttag 62040 tattttggga ggttgaggta ggcggatttt ttgagtttag gagtttgaga ttagtttggg 62100 taatatggtg aaattttatg tttattaaaa atataaaaaa ttattttggc gtggcggtgt 62160 gtgtttgcgg ttttagttat ttgggaggtt gaggtgagag gatagtttga gttcgggaag 62220 gtagacgttg tggtgagtcg agattgtatt attgtatttt agtttggatg atagagggag 62280 attttgtttt aaaaattaat gtatttgttt gtttgtttgt ttatttattt atttatttat 62340 ttatttattt atttatttag tttttgtttt ttaattttgt ttggtatgta gtttttaaaa 62400 tttttgaaat ttttaaagtg atgggtgttt ttttgtttgt taaggaggcg attggtggtt 62460 ggaggttttt ggatagtttg gggataaggg ttggttgtta ggggatttag ttttgtgatt 62520 agaaggttag aatttgtagt tttttttatt tattttttgc gaggtaagag gggatgaagg 62580 ttgagttgat tattaatggt taaagatttt atgttatgtt tatgtagtga agtttttttg 62640 aaaatttaaa aggatgaggt ttgtagagtt ttaggttgtt gaatatttgt aggtgttggg 62700 agggtagtgt attttttcgt ggaagtttta tgtcgttttt tttatatttt ttttatgtat 62760 tttttttagt tggttgttta tttgtatttt ttgaaatatt atttgtaata agttagtaat 62820 tttaagtaaa ttgatttttt gggttttgtg agttatttaa gtaaattatt gaatttgaga 62880 agggagttgt gaagatttta aatttgtagt taagttagat agaagttatg ggtaatttgg 62940 tgttttatta tttgcgattg atttttgaag ttgagggtag ttttgtgaga tggaattttt 63000 aatttatggg atttgtatta attttggttg gtgttagaat tgaattgaat tgtaggatat 63060 ttagttgggg attgttgagt attggagaat tgtttggggg tcggcgggag gaaattatat 63120 atttggtgtt agagttgaag tattgagtgt tgtgaatgag agtggagaga tagagtttgt 63180 tttgttttat gtaagaggat tttaaggagt atagaaagag taaatatgag aagtagttat 63240 tttagaagaa aatataggag gaaagtttcg tgatattgga gttggtaatg tttttttgga 63300 tgtgatatcg aaaatataat aaaagaaata aatgataaat tggattttat taaaatttaa 63360 aatttttgtg tattaaggaa tattattaat ggcgtgaaaa ggaaatttat agaatggaag 63420 aaagtatttg aaaatcgtat attcgataaa ggattagtat ttagaatata taaagaattt 63480 ttataattaa gttataaaat aaaaaaaaat aatttagtga atagatattt ttttatagaa 63540 gatatattaa tggttaagaa gtataggaag agatgcgtag tgttattaat tattagggaa 63600 atgaaaatta aagttataat aaaatatgat tttatatttt ttaaggtggt tgttagttaa 63660 aatatggata atagtaagtg ttggtaagga tatggagaaa ttggagtttc gtgtattgtt 63720 ggtgggaatg taaaatggtg tagttgttgt ggaaaagata taataattgt ttaaaaaatt 63780 aaatttagaa tgattataat atttagtgat tttattttta gatgtatatt ttaaagaatt 63840 gatagtaggg atttgaatag gtgtgttata tttttgtttg tagtagtatt ttttttataa 63900 ttaaaagatg taggtaattt aggtgtttat tagcggatga atgaatagat aaaatgtggt 63960 ttatttgtat agtggaatat tattttgttt taaaaaggaa ggagaggtta ggtgtggtgg 64020 tttacgtttg taattttagc gttttggaag gtcgaggtgg gtagattatt tgaggttagg 64080 agtttgagat tagtttggtt agtatggcga aattttgttt ttgttaaaaa tataaaaatt 64140 agttaggtat gggggtatgt gtttgtaatt ttagttatta gggaggttga ggtaggagaa 64200 tcgtttgaat tagggaggtg gaggttgtag tgagtcgaga ttatgttatt gtattttagt 64260 ttgggcgata gagtaagatt gttttaaaaa aaaaaaaaaa aaaaaaaaaa aaggagattt 64320 tgatatatgt tatagtatag atgagttttg aagatatgtt aagtgataga agttagatat 64380 gaaaagataa atattgtatg attttatttt tatgaggttt ttagagtagt taaatttaga 64440 gagatagaaa gtgggatgga ggttgttaga ggttggggga agggagaatg aatgggaagt 64500 tggtgtttaa tggggataga attgtagttt gggaagatga gatggatggt ggtgatggtt 64560 atataatagt gtgaatgtgt tttatgttat taaattgtat atttgaaaat ggttaaaatg 64620 gtaaattttt tgtgatggat attttaaggt atgtatgtaa atatatagaa gtagttatta 64680 ttattggggt tgatggaaaa gaaattaaga attcggagcg ttttttatat tttgttacgt 64740 tttacgttta ggttttgttg gagagtgtgt gattgttata gaaatttgta gtttattggt 64800 aataaaaagg tttttgttag aaggtgtaga aagagtggat ttgtaggatt agtttattgg 64860 gtagtcgaga aatttattag agggtatggg tgggtaggag ttgggtgttt gagaagtttg 64920 ttgaggtttt attgggttag agttggggtg ttggagaaat ttagtataga gtaggtttta 64980 ttgggtatac gttattggta gttgtgtttt tagaggaaaa agagattttg gaattaggaa 65040 gagaagttgt tattttagta aggtttggta gttttttata gtgttgtttt ttgtggatag 65100 agtttgatat gattgtattt ggttaaggag aaagatttat aaggtttcgg tttagtatta 65160 cggagcgggg tttggtagga tgtatgtaga gttaagaggt aatatatggg taattggtat 65220 atttttttag attttttgtt ttttttgttg ttttgttttg ttttgttttg ttttgttttg 65280 ttttgagaga gtattttgtt ttgttgttta ggttggagtg tagtggtatg atttaggttt 65340 attgtaattt ttatttttcg ggtttaagtt atttttttgt tttagttttt taagtagttg 65400 gagatgttta ttatgtttag ttaatttttg tatttttagt agagataggg ttttattatg 65460 ttggttaggt tggttttgaa tttttgattt taggtgattt atttgttttg gttttttaaa 65520 gtgttgggat tataggcgtg agttatattg tatttggttt atttttttag atttttaaag 65580 tagattttta ggtttttttt tttttttttt tttttttttt tttatttttt ttttaatata 65640 agtatttata gttttttttt aagtattagt tttagtttac gtattttagt atgttgtgtt 65700 tttattatta ttttatttga aatattgtaa aatttttttt gtgatttttt ttttgattta 65760 tgggttattt agaagtatgt tgtttaattt gtaaatagtt aaggtttttt tgagtatttt 65820 agagttattg atttttaatt taattttatt ttggttagat aagtatattt tgtatgtttt 65880 taaaatttga gatttatggt ttagaatgtg tattttggtg aatgtattgt ttttatttga 65940 gaaaaaaata tgtatatata ttttagattt tttgagtata gagttttata attgttgatt 66000 aggttaattg ttagttatta gtgtttttta gattatttga tgtttgtttt ttagatgttg 66060 agagaatggt gtttgttatg gtttatttgt ttgtgttttt taaaatttat atgttggagt 66120 ttaatttttg gtgtagtggt gttgggaatt ggggtattag ggaagtattg gtttatgagg 66180 gtagagttat cgtgaatggg attagttttt tttgttatgt ggggatatag taggaaaagg 66240 atatttttga agtagggagt tagtttttat tagatattga gtattttgat tttggatttt 66300 ttagttttta gaattgtgag tattataatt tgtttataaa ttatttagtt taaggtattt 66360 tgttttaata ttttgaatga attgaggtgg tgttaaaatt tttaattatg tatttaggcg 66420 tagtggttta tatttgtaat tttagtattt taggaggtta aggcgggtgg attatttgag 66480 gttaggagtt tgagattagt ttggataata tggtgaaatt ttgtttttat taaaaatata 66540 aaaattagtt gggcgtggtg gtaggttttt gtaattttag ttattcggga ggttgaggta 66600 ggagaatcgt ttgaatttag gaggtggagg ttgtagtgag tcgagattgt attattgtat 66660 tttagtttgg gtaataagag tgaaatttcg ttttaaaaaa aaaaaaaaag agtttttatt 66720 tatgattgtg gaattgttta tttttttttt taattttttt aggttttata ttatgtattt 66780 tgaagttttt ttggttaggt gtatatatat ttatgattat aatggtgttt cgatgaattg 66840 attatttaat tatgatgaat gtattttttt atttcgtaat aattttattt tggatttaat 66900 tttattgata tttatgtagt ttttttagtt tttttaaata tgttgtttgg gatgtataag 66960 aaggttggag aggtttatgg agaaatttat gatggtttga tttatagttt tttaatttta 67020 ttatggtgcg aacgtggtat gtatatagta gaaattgtat tttaagtatg tgtgaaatta 67080 ttgtgttttt tatttttagt atagtattta ataatttata tgagatagtt aatattttat 67140 tataaaatag gttttgtgtt tgttgatttt gtttaattgt aggttgaagt aagtgtttta 67200 attatgttaa ggtaggttag gttaagttag aatgttcggt aagttagatg tattaagtgt 67260 atttttgaga tgatatttat tttttattta tgatgggttt gttaagatat aattttatta 67320 ttatttaagt agtattagta tgtttttttt taaatagaaa attttaattt gtgtttatat 67380 tgaaatagta ttttttgtag atagtatata gttgagtttt gttattttat ttattttgat 67440 agttttcgtt ttttaattgg aatatttagg ttatttttgt ttaatatagt tatagatatg 67500 attgggttta gagttattat tttgtttttt gatatttatt ttttttattt tgtttttttg 67560 gtttttttta tgttaattaa gtatttttta gaattttatt ttaatttatg tttttttttt 67620 tttttttttt ttaagataga gttttatttt gttgtttagg ttggagtgta atagtatgat 67680 tttggtttat tgtaattttt gttttttggg tttaagtgat ttttttgttt tagttttttt 67740 agtatattgg gattatagac gtttgttatt acggtcggtt aatttttgta tttttagtaa 67800 agacggggtt ttattatgtt ggttaggttg gtttcgaatt tttgatttta ggcgattcgt 67860 ttattttggt tttttaaagt gttgggatta taagcgtgag ttattgagtt cggtttgttt 67920 tgatttttta attgtatttt tttgtattgt tattttagta gttattttat agattttatt 67980 gtatattttt agttttttat agtttattta gaattaatat tgtttttttt tatggaaaaa 68040 aagtgtaaga attaggtaat tttatgggtt tatttattat tttttatttt gtatgtgatg 68100 gttgttagat atttattata tttatatata ttgtaaatta gataatataa taaggaaatt 68160 tttgttttaa atagttttat gtattttaaa gaaattaaaa gtaaaataga atttttttta 68220 tttgtttatg tatttgttat attttgtgtt ttttattttt ttttgaagag ttgagttttt 68280 atttggtttt attttttatg attttggaga atttgtttta cggtttttgt agtgtaggtt 68340 tgtagatagt taattttttt ttatttttat ttatttgtaa atttttattt tgttgttatt 68400 tttttttttt ttatttttat ttttattttt gagatagagt tttattttgt ttttttatag 68460 gttatagtgt aatggtgtga ttttaaaatt tttgtttaat tttaatttat taattttttt 68520 ttttcgggtt taaacgattt ttttgtttta gttttttaag tagttgggat tataggtatg 68580 tgttattata tttagttaat ttttgtattt ttagtagaga tgggatttta ttatgatggt 68640 taggttggtt tcgaattttt gattttaagt gatttgtttg ttttggtttt ttaaaatgtt 68700 gggattatag gtgtgagtta ttgtgtttag tttgttgtta tttttgaatt ataattttat 68760 tggttataga attttgagtt gttagttttt ttttttagga ttttaaaata tagggtttta 68820 gtgtttttgg ttttcgttgt ttttgttaag gaattagtat ttatttagtt atttttttgt 68880 agattatatg ttgttttttt ttggatgttt ttaagatttt ttatttaagt ttgattgttt 68940 agtatttatt tttgggtaaa aaagttttta gaaattagaa atttatttag ttttattttt 69000 ttttgttagg tgtagatttt attttagttt ttatttattt gagatatttt atattgattt 69060 taggttgttg ttattttgtt tttttaaata ttttgtttag agttataatg ttttttgtag 69120 aattgattag atagtagtta ttttttgtga ttaggagttt tgatttttta gatttgttga 69180 tgggtttata aagtttttgt tcgtggtttt tagttggtag tggttttttt gttttgaagt 69240 tgttatgagt gtgtaaaatt tataggttta atttttttta ttagtatagt ttagaaaagt 69300 ggaatttttg gtttgggtgg ttatggtgtt ttagattatt ggttagatta gggtggtgat 69360 tgttagttgg tcgaatgtgg ggtttttagt ttagtatttt tggattttat tttaggagtt 69420 atggttgttt tagggttagg ggtttggttt tagtttttgt tttttttttt ttttttttaa 69480 gttgtttagt attaggtttt aattagtatt ttttgtagat agggtgggtc ggttttttat 69540 tagaggggta gggttgggcg ggaagtttgt tgagtttttt tttttgtgta gtttatagtt 69600 ttggggttag ttttagaggg gtgtagaaag gagtttttaa aggtagaaat ttattttttt 69660 ttttgttttt gtgtttttag ggataaagga gaggtggttt tagttggggg gttattagtg 69720 gtatgtagga ggtttatatg attattgttt gttggggttt tttttttttt gtgagagaga 69780 cgagagagag gagagagagt gtgagttagg gtagtgtttt tttttagtaa cgtagatttt 69840 tgtacgtgtt ttttaggaga aatttcgtta ttcgttagag ttttagattt ggaagaagtt 69900 ttgttttttt tttttttttt agtgtagtgt gtgtgtgtgt gtgtgtgtgt gtgtttttat 69960 atgtattata tttttttata gaggaaataa ttttcgttta agtgtaaagg ttgggattgg 70020 agtaggtagt atgtgggtta aaggagtaga gaggaggaaa cgggggcggg ggtgagggtg 70080 ggaataggag gtgggtagat gttacgaggt atgtttttta taattagaag ggttggtgga 70140 gatgattaga atgttttaga tagatttttt attaaatttt taaaatttaa ttttgtttta 70200 tgaagtttga ggattttgta gagtgaaaga taaggaaggg tttttttgta ggggggtgtg 70260 tgtgtttgtg tgtgtttgtg tgttgtgtgt ttttatgtgt gtgtacgtgt ggatttgtgt 70320 ggtgtgtgtt tgtatatgtg tgtacgtgtg gatttgtgtg gtgtgtgttg agtgtgtata 70380 tgtgtgtgtt tgtgtgttgt gtatgtattt gtatatgtgt atatagattt tatttttttt 70440 ttttttggtt tattaagtgt tagaaagaat tttcgtgagt ttttttattt tttttaaggt 70500 tgtatatgga gggatttgcg taggtatatg tgcgcgtgta tataatatat atatatatat 70560 atatatatat atatatatat atatacgagt taggggcgag tatttttgtg gattgtattt 70620 aggtttggta ggaaatcggg ttttgggaaa ttgtaggttt tatttttggt agaaaattat 70680 gtttttgttg ttgttcgttg aagggaatat taagtggggt tggggatagt ttatgttgag 70740 aagagtaaat tttgtttatg gtattgggga tattgagtgg tttttgtttc gggttttgga 70800 gggtttggga gatacgtttg tagttttggg tattttttaa ggttacgggc ggttatattt 70860 aaggttaggt ttttttttgt gtgagttgcg gttagtagga aggttgattt tagaggcggt 70920 tttagggttt ttggaggttt tgtttttgag atatgggtta aggttagaga gtcgagaagg 70980 ttgttgttga ggattttggt tggcgtttag tttagcggtt ttttaggcgg gttttgtgta 71040 ggggttgatg aagttagttg ggaaatttgt gaaataaagt ataggttttt taggtttgtt 71100 tagagtttcg gtattagatg aggtgtagag aagggaattg agttgttaag tgtgaatagg 71160 agagaggagt tttaggatta tataggggtt tcgatatggt aggtgtttgg ttagtagcgg 71220 tgttgttttt attgttggac gtgggaaaat gtattgatat ttgttgatta gagtcggggt 71280 gagtatttgg gtgattttgt agatgagata aaataagggt tgtcgtgggg gaggggtttt 71340 tgtcgggtta ttttgttgag gttttgtgtt attgttttgc ggttgttata ataaaggatt 71400 ataaatgagg tgatttaaaa tattcgaaat cggttacgtg cggtggttta tgtttgtaat 71460 tttagtattt tgggaggtcg aggcggttgg attacgaggt taggagatcg agattatttt 71520 ggttaatatg gtgaaatttc gtttttatta aaaatataaa aaaaaaaaaa aaattagtcg 71580 ggcgtggtgg tgggtgtttg tagttttagt tgtttaggag gttgaggtag gagaatggta 71640 tgaattttgg aggtggaggt tgtagtgagt cgagatcgcg ttattgtatt ttagtttggg 71700 tgatagagta agatttcgtt ttaaaaataa aaataaaaat aaaaataaaa atattcgaaa 71760 tgtttttttt aaagtttttg gagttagaaa ttttagatcg aggtgtttga aggtttattt 71820 tttttggggg tttcgaggga gattgtttta tgtttttttt cgagttttgc ggcggttagt 71880 aatttttggt atttttcggt ttgtagttcg gtttattttt tatttggttt ttattttgtg 71940 tttttttttg tgtttttgtt taaattgttt tttttgttgt ttttttaatt tatttttagg 72000 gataggtttt tattttgttt tttaggttgg agtgtagtgg cgtgattatg gtttattgta 72060 gttttagttt tttaggttta agtaattttt ttattttagt tttttaagta gttgggatat 72120 aggcgtacgt tattatgttt ggttaatttt ttaatttttt tgtagagacg agggtttagg 72180 ttggttttaa atttttgcgt ttaggtaatg agattttgtt ttttaaaata ttgggattag 72240 agatatgagt tgttgtgttt agtttatttt tgttttataa agatatttgt tattggattt 72300 agggtttatt ttgatttaat atgtttttaa ataatttaat tatattttta aagattttat 72360 gtttatataa agttatattt ataggtattg gggggttagg atttgtatat gttttttggg 72420 ggaatataat ttaatttata atgggtttta tttatagaac gaacggtttt tttagggtgt 72480 gcgtaggtgg gtgaggggtt taggagaggg atttgcgtgg taagagggtt tgtgtttacg 72540 ttagagattt tagaaggaga ttggatgggg tggttgtatg gagtaagggg ttatagttat 72600 tgtttttaag tagttggtgg gttgtttggt agaaagggag tatttatttt gagttttttt 72660 aagatatgaa gttagtatta ggtatttgga aggtgttagc gagtagagtt tgatttttta 72720 tagaaagagg tgtttttttt ataatgttta tttgaggacg gtggaatagg ttattttata 72780 aggtagtgag ttttttatgt ttggaagtat ttaagtaggg gttatgtggg agttgtttag 72840 gagtgtatag aagggatttt agaggttttt gttaatatta tttttgtttg ttttatttta 72900 cgataatttg aattttagaa tgtaatgtta ttggggatat gtttattaga ggggttttta 72960 gtattaggtt ttatatatta tgtattattt ttagggtagg gaatgagagt aggttttatt 73020 ttttttggtt gtttgtgagg attaggaggt ttgttgttga ggtagttttt tgtggaaata 73080 gtgttttagt ttcgtaattt atttatcgga gttttaatat tttaatgaaa tattgtgtta 73140 gatgggtttt gggtatgtgt gtgtagattg ttataagttt atgagaatgt atatacgtat 73200 attgtatgtg tgtgtatata tgtatgtata tatgtataag aatacgaaga ttcgaggtag 73260 gtatagttcg tgagatagat ttttttaggt tgaaagattt tttataaggg tttttagaat 73320 aaggttttag tttcggtagt tttttttatt tttggtggga ggatttttat agagaagaag 73380 ggttaagaag tatagttttt gatgtttacg gtgtattaag ttttgtttta agtttgtgtt 73440 ttatttttta tttatttagt aaatttgtcg tttttgtttt gtgttagatg ttgtttttag 73500 tattttataa atattgatgt atgtttgttt tatgataatt ttgtgaagta ggtagtgtta 73560 tttcgtttta tagatgagga aataggcgta gagggataaa gggatttgtt taaggtttgt 73620 ttttatttta tacgtatatg aacgtttatt tatgcggtag gcgttagttt ttttttgatg 73680 tgagttaggt tttgagttgg ttggggtttg ggttttattt tggttgtgtt ttgttgtggg 73740 tattaaggaa gtttttagta gttttatttt tttggtatga tttagtttta gggattggat 73800 ttttttaaat gtttttgttt agtttggagt ttttttttta gttgggggag ggttgaacga 73860 ttttttattt ttggaggttg tcggagtttt ttttgtttgt atgcggtcgt tgtcgggtgg 73920 ataggtttgt ttgtgggttg aggtttttag tagttggggt ggattatttt tttttttaag 73980 aagttttggg agaagtagtt gagggggtta gcgttttttt gaggttaatt ttttgttttt 74040 tttagcgtag gcgcgaagtt atttttgttt gtgtgtttgt tatagatagt ggagggcggt 74100 gtaatcgtga cgtttgtttg ttgtattttg cgtttttgag gacgttgatt tttggtcggt 74160 gttgggcgtt tgttttttag ttattttgtt ttgatttggc gtggtaggtt cgagtattgt 74220 ttttttataa ggaaataggt ttagaggttt tgagttattt gttcgggttt ttttagttaa 74280 taattggttg agttaggatt tttatttagt tttgtgattt tagaagttta agtttttttt 74340 attacgttag ggttaggaaa ggattagaat gtttttttac gtgtcgatta tttggatgat 74400 ttgtgtagtt tagttcgttg tagttgttta ataaaaatgt ggaatgaatg ggtttatatg 74460 ttttattgtg tgatttagag ttaatgattt tggttgattt ttttgttttt atttcgtggt 74520 ttagtatttt tttttggggt gtgtgatttt ggaagtagtg atttttttta ttttattttg 74580 aatggtgttt gcgtcgtagt aggggagtag ttggggattg ttagcgtttg ttgttggtgg 74640 gttgtgcgtt agatttcgtt ttggatgtgt gggtgattgt tagttatatg tgtgtgaagg 74700 gttgtgcgtg taggatttgt gtaaatgtgt ttttttttgt tgttagttta tgggaggttg 74760 ttaagatttt gtttttgtat attagtttat attttttttg tggtttattg ttgtggttgt 74820 ttttttgtgt tacgtggttg taggtatagt ttttaagtgg atggggatcg tgggttgaat 74880 gtgtattaga tgtttttgtt ttttggtggg tggagatttt taatttatgt atcgtggttg 74940 tcgtatttga aaggtttttt atggtgaagg atttggattt gagtaatttt tcgtagaggt 75000 tttagaagtg ttttttggtc gggcgcggtg gtttatattt gtaattttag tattttggga 75060 ggtcgaggtg ggcggattat aaggttagga gatcgagatt attttggtta atacggtgaa 75120 atttcgtttt tattaaaaat ataaaaaatt agtcgggcgt ggtggcgggt gtttgtagtt 75180 ttagttattc gggaggttga ggtaggagaa tggcgtgaat ttaggaggcg gagtttgtag 75240 tgagtcgaga tcgcgttatt gtattttagt ttgggcgata gagcgagatt tcgttttaaa 75300 aaaaaaaaaa aaatgaagtg tttttagttt ttttttttgt ggtgaggttt tgagttttta 75360 tttttagaag aaaatttggt tggggagggt atttttagat tcggatataa acgttaggag 75420 attagggttg tttttttagg tgattaatta tagagattta gggaaagtta cgtttggaag 75480 aggcgatatt gtgttttagt tttatttatt tttttatttt atagatattg tttggtgttt 75540 agttcgtatc gcgaggtttt ttaagtagtt ttgggtatcg tgtatttggt atggttttta 75600 gttttatttt tttgttttgg gagattcggt ggggatttcg ggttgagttt ttgtggttgt 75660 ggaattttgg tggtttattg tggtggttga gaatagggac gtggggttgg acgggttgag 75720 tgtaattttt agtggtttcg tgaattgttt gggagttttg ggtagttttt ttttattttg 75780 tgttttcgtt ttttgatgga aaaatggggg ttagggggga gcgattttga aggtattcgt 75840 gggaattaag cgaggtgata aatgtagtgt ttttggtaga gaattggata tagagtttat 75900 ttttatgaag ggggttgttt tttttttttt tatgtttttt tttgttttta tttttttttt 75960 tgtatttttt ttttttgttt tttttttttt tttttttttt ttttatatgt aggtatattt 76020 tatttggtgt tttaattgtt tttttttatt gtttttttgt aagtggtttt ttaagtggga 76080 atttaggttt ggaaagggtg ggtattttgt ttggtgggtt ttggtaggtt aggcgttgag 76140 tagttttagg agatataatt ttaggaaaag gtttatgtag gttggttgtt atgacggatt 76200 gttggtggga gaggggaagg cgtcgtggta ggggaagttt tggaaatatt tattagtggt 76260 tttatttatg atttaggata tttgttaggt tattagaata tagttgagga agttgtcggt 76320 tagacgttta gaagtattaa tttggtggtt gggttgtggg gggatttttt tggataggta 76380 gataaggtgt cggaggaagg ggttgatatt tatttagtgt ttgttatgta ttgagggtat 76440 aaagggtagg atggagagtt ggtttacgtt atttgtggaa ttttttaggt gtgggggtag 76500 atggggaagt aagggggttt gaagatatat gcgtttatta aatgttttta aattttaaga 76560 agaagaataa ggatatattt ataggggtag ggttgaaagt ttgatgtatg gtgttttggg 76620 gtttgttttt gttgtaatag ttatagtggt ttttttttat tttttttttt tttttatttt 76680 gttgtgaaaa tgtttaaaat atatggttaa gttgaaagta ttttataggg aatatattta 76740 gttattattt agattttatt attaatatta agttatattt gttttattat tttatcgttt 76800 atttattttt ttttcgtttg gttatgaatt tattttattt ttattttttg gtgtatttta 76860 aagtaatttt aggttatttt gattattttt ggaattattg ttagaaattt tttttttttt 76920 tttttttttt tttttttttt ttttttttga gatgggattt tgttaggtta tttaggttga 76980 agtgcggtgg tgtagttata gtatattgta gtttttaatt ttcgagttta agtaattttt 77040 ttgttttagt tttttgagta gttgggatcg taggtattta ttattatatt tagttttatt 77100 tttaaaattt tttattaatt ttttattttt tgtatttatt taggattatt ttttataaag 77160 ttagggtgtt gtaggagggg ttagaatttt aagttttaat tttggttttg ttattaatat 77220 tgtgcgattt ttagtaaatt attttgtttg tttaggtttt gtttttattt ttatgaaacg 77280 agggcgttaa attgtatgtt ataaataatg agggttatta gttattaagt ttttatttta 77340 ggttaggtat tttttatatg ttattatgag tttttttaat ttaggtattg tttttaatgg 77400 atagtttagt taacggaagt ttagagaggt ggtgtaattt gttaaaagtt ttattattta 77460 gtgaatgttt ttacggggtt tgtatttagg agtttgatat agagtttagg ttttagtatt 77520 tggcgatgtt ttgggggtgt gagtagttta gtttattttg ggtacgtgtt tatttgttgt 77580 tttttttgtt ttatgtttgt gtttgttttt tttgaagttt agattgttat tttttagttt 77640 taaatattaa aattggttag gtacggtggt ttatgtttgt aattttagta ttttgggaga 77700 ttaaggcggg tggattattt gaagttagga gtttaagatt agtttggtta atatggtaaa 77760 attttatttt tataaaaaat ataaaaatta gttagatatg gtggcgtgta tttgtagttt 77820 tagttattta aggagaattt agttatttag ttattgaggt acgagaatta tttaaatttg 77880 ggaggtggag gttgtagtga gtcgagatcg tattattttt ttttaggtta ggtaataagt 77940 gtgagatttt gttttaaaaa taataaataa ataaaataaa ataaaaatta aaattaaatg 78000 ttaaaattaa tttataaaat aaattttggt taaagtagtt tgtttatttt gttttaatta 78060 tgtatattgt attagatttt gttaggggtt tagcgtataa agatgagatt tttgttttgt 78120 tagataggtg ggatgatggt tatattttga gttagttaag gtattatttg gttgtgtaat 78180 aaaagttaaa atattagagg ttgagtagta ttcggattta cgttttagtt taagtgttag 78240 tcgttatggg ggtttaggat agttcggatt tagtttattt ttttggtgta ttttcgatat 78300 atagttttta ttttttgagt tgagatggtt ttagtttttg tcgttatgtt tgtattttag 78360 ttagagggaa gggaagaagg gagaggggaa agggtaagtg ttttttttta tttttaaggg 78420 tatgatttga aagttaaata ttttagtttt tttttattgg ttagaattta gttgtatggt 78480 cgtttttgtt attagggagg ttgagtaatg tattttttag ttgggttttt ttgtgtataa 78540 ttaaaatttt agttattata gaaaaaaggg agtttagata ttggggaaat aattagtatt 78600 tgtattatat gtattgatag ttttttttgt atgaatagag ttgtggtagg ttttatgtta 78660 gggagaaagt aagattggaa aagagtttat taaggaggtg gtatttgtat tgtgtttaag 78720 gggtaagaaa aacgtttttt aattaggagt tataaatgtt tggttgaagt gttattgttt 78780 ttttattttg gagttggaat agacgttatt agttaattat gatggttgtt gggtgtattg 78840 gttaatattt ataattttag tattttgtga ggttgagggt gggaagattg tttggggtta 78900 ggagtttgag attagtttgg gtaaattgta agattttgtt tttgtaaaaa aatataaaat 78960 gtagttgagt gtggtggtat ttgtagattt agttttagtt attcgagagg ttgagatggg 79020 aggatcgttt gggtttagga gttcgaggtt gtagtgagtt atgattgtat tattgtattt 79080 tagtttgggt gatagagtag gatttgtttt taaaaataat aaaataaaat taaagtttta 79140 aaatggaaaa aaaattatga gtatataatt ttagatgtat ttttaagata gtaaattcgg 79200 gtgggcgtag tggtttatgt ttgtaatttt ggtattttgg gaggttaagg tgggtggatt 79260 atttgaggtt aggagtttga gattagtttg gttaatagtt ttatttgtat tataaatata 79320 aaattagttg ggtatggtgg tgggtatttg tgattttagt tatttggaag gttgaggtag 79380 gagaattgtt tgaatttagg aggcggaggt tgtagtgagt taagattata ttattgtatt 79440 ttagtttgga gaaaaaaagt aaaattttgt tttaaaaaaa aaaaaaaaaa gtaaatttag 79500 ggttaggttt gtagttatat ggttattttt ttttttgagt atggaggtag ttttagaaat 79560 ttgttttata ttatattagt gggtagttga ttgggttagt ttgttagttg aattttattt 79620 gttatagtta ttttttatag taaggggtat tttagatata tttttttttt tagggaagaa 79680 taagtcgtag ttgtttgagc gttttattta gtggtgtgta tgtttttttt taattttgtg 79740 tttagtgatg ttttgtttgt agtttgaaat ttgttatagt gggtgtgttt atattatagg 79800 aattggtaaa tattatatat taggttttat tttttgtttt ttattagggt aggttgtttt 79860 ttttttgttg tttttgtttt ttgttttttt ttttttttga gacggagttt cgttttgtcg 79920 tttaggttgg cgtggagtga tgcgattttc gtttattgta agtttcgttt ttttggttta 79980 tattattttt ttgtttgagt ttttagaata gttgggatta taggcgttcg ttattatatt 80040 cggttaattt tttgtatttt tagtagagac ggggttttat cgtgttagtt aggatggttt 80100 cgattttttg atttcgtaat ttgttttttt cggtttttta aaatgttggt attatgttat 80160 tgcgttcggt ttagggtagg ttgttagaaa tgtattagtt tgttagtttt agttttgttt 80220 gttttttatt tttttttttt tttttttttt ttttgagacg gggttttttt ttgttgtttt 80280 ttaggttgga gtgtagtggt gtgattttgg tttattgtaa tttttgtttt ttgggattaa 80340 gtgatttttt tgttttagtt ttttaagtag ttgggattat aggtgtttat tattacgttt 80400 agttaaattt tgtattttta gtagagatgg ggttttatta tattggttag gttggtatcg 80460 aattttttat ttaaggtgat ttattcgttt tggtttttta aagtgttggg attataggcg 80520 tgagttatcg tattgggttt ttttcgtttt tttttaatga aaattttttt gaaagatttg 80580 tttattgatg tttgtgttaa taggtattgt ttgcgggata gagtttgttt tttttttgaa 80640 ggtttttttt tgtttgggtg attatttgta tgttattttt tgttgtttag aattaaagat 80700 gtagttatgt ttggggtagg ttgggaaaat ttgtgggaat tatagagttt gttgttatgt 80760 tgtgttttgg atatttgaag tttggtaggt aggtgggatc gagggtgggt attaggaaag 80820 tgatgtggtt ttataggaag gggatatagg ttttgagatt ttaggttttt aattggataa 80880 agttgttttt tttttttgga taaatgtttt agtttattta taatcgagtg gttagttttt 80940 tttttttttt tttttttttt ttttttgaga tggagtttcg ttttttcgtt taggttggag 81000 tgtagtggcg ttatttcggt ttattgtaag tttcgttttt taggtttacg ttattttttc 81060 gttttagttt tcggagtagt tgggattata ggcgtttgtt atcgcgttcg gttaattttt 81120 tgtattttta gtagagatag ggttttatcg tgttagttag gatggtttcg attttttgat 81180 ttcgtgattc gttcgtttcg gttttttaaa gtgttgggat tataggcgtg agttatcgcg 81240 ttcggttaag tggttagttt ttttagttgt cgggttttgt atattttgtt ggttttggag 81300 attatatgta ttatgtagat tttatttgtt ttttattttt agtgttgggg gaggggttaa 81360 gggtttgtcg atgtgttgat atttggttat ttattggttt tgaatgttta tatttatttt 81420 tttgaaatcg atgtttcgta tcggaggttt tatgtggatt tgggggtaga ggtttgtatt 81480 ttagatggtg gggtggtttt tattaattag gtagattttt tgttttgttt tgttttttgg 81540 gttttgtagt tttagatgtg tgtttaagat ttgtggttat atggatggga taagttatag 81600 agatttagat ttcgtggttt ttgtgattag agtagtcgtg gttttgtttg ggaatgtttt 81660 tattttgttg ttgaaggtga gaaatttttt tgtgttggag aatagttgtg ttgagaagtt 81720 ggtttatttg gtttgtagga ttgttggggt aagggaggtt tgttgtcggt tttttttttt 81780 tttttttgat tgggtgtttt ttgtttaggt tttttgtagt aaaagaattt tttaatttat 81840 tttgtttttt tattgagttt ttattttatg aagtttattt tttaatttta gttgattggt 81900 ttttattttt ttaagaggaa ggttaggggt agacgaggtt gaaggaggtt gatttttttg 81960 tgttttcgta gtttgagttg atgttgttgt atgtttatag ggttttttta gtttttaaaa 82020 aggttttaat acgttcgtta tacgtttgtg gtttttttgg atgttatatt aatttagtaa 82080 ggtttgagtt agaggttgtt tttgaggttg tgaaaataga agaagggttt agaggagaat 82140 ttttttattt gacgatttta ggaaggtttt ttagaagaag tagtttttga gttgagattt 82200 gaagatagat taggtttgag ttaggttagg gagggtgtga ggggtttatt aggtagaggg 82260 aataggatag ggtaggtata gaggtttggt atttggtttg tggggaagtg tgagtttttg 82320 ggtatgatta aggcggggag aagtggcgtg agaggaggta gatgtggttg gtaggagatc 82380 ggcggtttcg gttttgttga gttttatttt gtatgtatta ggtgatagag gttgtttagg 82440 acggtgggta gggaagtgat aggttatatg gttattttat taatagtcgg gagtttagtt 82500 tggggggatt taagattttg gggaaggtac gagttagggg tttgttagag ttaggagtta 82560 gtgggagaag gaaatagtgt tgtttatgaa ttataaatag atattttcgt aatttttttt 82620 gacgtgatat aattttaaag tgggttattt agaggtggga aggtgatttt tggtttttta 82680 ggttttgggt ttgttttttt tttttttttt tttttttttt tgagatggag ttttattttg 82740 ttgtttaggt tggagtgtag tggtgtaatt ttggtttatt attatttttg ttttttgcgt 82800 ttaagtaatt tttttgtttt agttttttga gtagttggga ttataggtat ttgttattat 82860 attcggttaa tttttgtatt tttagtagag atggtgtttt attatgttgg ttaggttggt 82920 ttcgaatttt tgattttagg tgattcgttt attttggttt tttaaagtgt tgggattata 82980 ggtatgagtt attgtgttta gtcgagttta tttttaagtt ttttttggtt tttagtgttt 83040 ttgtattagt ttattttttt ggttttttgt ttttaagagt tttttttaag attgttttta 83100 agtggatagg tttttagaat taaggagtag ttttaggagt ttttagttat agatatttta 83160 gggggttcgt gtggttttta gtttttggtt tggtttcggt agttttggtt ttttgtgttg 83220 ttttttatat agtttggtta gagttggtta ggttttttgg ttgggtcgag ttatcgtggt 83280 tagtgattta tgtaggggga gaaaagtgag gagggggaat agagtgcgag ggggattgtg 83340 ttaataataa atttattagg tttttgaggt tattttatag gagggataaa tggtttattt 83400 aggttgattt ggttgtcggt tggtttttag agatatttag ggtggggaag attttattat 83460 ttggggaaag taatattaga ttgtttggag gggtttagtt agcgtatttc gcgttttttg 83520 tttgtttttt acgtagagcg ttttgttttt aaggcggtag gttaagagcg cgagtcgagg 83580 tttaggtgta aagaggggtg cggtatgggg gtattgtagg gtacggggtg tatgtatttt 83640 tatttatttt tttattgagt gttagggtaa tttgttaatg gggtatattt ggtgatataa 83700 aattttttgt cgatttatgg tagtttggaa cggagtggaa gcgttttatt tttggggaat 83760 ttttatatat atttggttgt gaacgtcggt gtttttgtat tggagttttt ttggagtgtg 83820 ttgggtagag cggagaggtt tttttttttt tttttttatt attttgtgga ggtgttaata 83880 tgtagttaga gatggttagt ggtagtgagg agaggggggt aggaagagat tagggttggg 83940 ggtttgttag tttatagttt tatttttgaa tatttatggt ttttttgttt aggttagcga 84000 ggttgggggt agagacgggt aggggttttt taatgttggg tattttttcg tttttttata 84060 ttttggattt gttttttgga gaaagttttg gagtatttag aagttttggg gttgttggtt 84120 gaggtgggga gtagagttta gttgtgtttg gaggtttttt atttttattt agtttttagg 84180 gatagtttta gttgtgtagg tttaggtcgt tgaggttggt tttagaaatt tttttataat 84240 tattattgga tggaaaatta gttttttaaa gggttttaga gttagttttg tttttttttt 84300 tataggtttt tatagttaga gtatcgggtt tttgttagag atgtagaaga gacgatgttt 84360 ttagttttta tgtggttcgg tttttattgt ggatgttggt gattttagtt ttttttttaa 84420 aattaagagg gttgatgttt tatattttag gtttttagaa agagtcgtta tttatttata 84480 tcgttatatt ttttttttat ttttttgttt cggaaagagt agagtggata tgcgtttttg 84540 tagaaattta tttatagttt gattgtagat gtattttgtt tttttattga gtttttgttt 84600 tatgaagttt gttttgtttg tatttttttt tttttttttt tttttttttt tttttttttt 84660 tttttttttc gttttttttt tttttttttt ttttttgttt tatttttttt tttttttttt 84720 tttttttttt tttttttttt tttttttttt gtttttttta tttttttttt tttttttttt 84780 tttttttttt gaatagttaa agatagaatg aatggtatag gtaggtattg agttttttgt 84840 aattggaggt gtttaagtgt agggtggatg ggtatttata gggtaggtat tgaggaagga 84900 tttttttggg attgtggatg gtaggatagg ttttgtggag ttttttgagc gggtgtagaa 84960 gagggagggt atgtttttgt tttttgtttt tttcgggttg ttaggtcgtt atttttaatt 85020 tttatttttt ttttttttat ttgttgggtt ttacgggatg ggtagaggta ttgttagaat 85080 atggagtcgc ggtttataga gggttagtag ggaggagagt tttttgggga ttacgtcgtt 85140 ttagttattg tggtgatttt gaaaataaat gttttttttt ttgtttgagt ttttgttgtt 85200 tttgttgacg tggaattagg gtaggttggt gatttagttt ttatttttgt attgtatcgg 85260 tggtaagttg tttttagttt tagattttat agagtagggt gtttttttta gaaaaatagt 85320 agggaggtta ggatattaag ggttttaggg atagtttgtt ttttttggtt ggtatgagtt 85380 ttagttaagt tttttggtat tttgggggtg aggaggtatt agttgtgtgt tttagttatt 85440 ggttgttttg aggttgggtc ggtgttaggt tggttatttt tttttgtttt ttagtgtgat 85500 tttgtagagt tttcggaagg gttagagggt ttttttttat tattggtgtt tatgggatat 85560 tgtgttttta ttttattttt gtattttagt tttagacggg tgttaggaag ttggagattt 85620 tagttatttt acgattgtgt tttgcggggt tggagtagga ataggagtag gaggaacgtt 85680 ttggttatgg gattgtgtga agagagaagg attaggaaga aaatatgagt tattatgttt 85740 gggttatatt ttagtagagt cgttggtggt tttttaggta tttgaattta ttaattataa 85800 agtttattag gtgtgtaaat aaataaatgt tgtttaggag gtatagttag ggttttgttg 85860 gagagggatt attttggagg ggttatattt tttatttagt tttttagttt ttttgttttg 85920 tgtgtgtgta gtttttgatt attattattt ttgtttttgt tatttgtttt tagggtttta 85980 ttaggttgga tgttattgta ataaaatgta gtaatagaag gtttaggtag tgttgtagtt 86040 tttggtggta ttattagagt tagtaggtag tagggttggg gaattttaag ttgatttagt 86100 tttaagtgtc ggagcgggga gttcggatga ggtgggggtg gggaatcggg gagttatgga 86160 gtagagtatt tgttgtgttg aaggttagga gtttttttgg gagattatga atttagaata 86220 ttaatatttt gtttaaaaag ttttttgttt tggagataag agtttaggtc gttgtggtta 86280 ggttttgttg taaatgtttt gtataaagta ggttgggggg attattggga agtttgggga 86340 atagattggt tatgtgtttt tttgagtgaa attttatggt tgtattgaag cggttaggta 86400 gagggtgtga tggggtgtgg tagttgtata tcggtttagt taggttgaat ggggaaatgt 86460 aaatttaggt ggtttgaaag agatttagtg gtttatagtt tggtggttgt ttttagtata 86520 ggtgatgtaa agagagaagg ggtttcgggg gtttggttta ggtggaaatt atgtattgtt 86580 tgtgattttg ggtatgtcga ggttggagta ggtttgtttg gtggttggta gaacgtatat 86640 gaagaattta tgtgtgtttt gaacgttttt tttgtttttt tgggtttatg ttttattagg 86700 agtttttcga ttttgttatt ttgtaaagga aattgcgttt tgttattgta taggatcgaa 86760 taggtgtgtg tggagttttt aaagttattg ttttaagggg ttttatggga taatgggaga 86820 gttgttgtga tgtttaagat taaagtgatg gttgggcgta gtggtttacg tttgtaattt 86880 tagtattttg ggaggttgag gaggatggat tatttgaggt taggagttcg agattatttt 86940 ggttaatacg gtgaaatttt atttttatta aaaaaataaa aattagtcgg gtatggtagc 87000 gggtgtttgt aattttagtt attcgggagg ttgaggtagg agaattgttt cgatttggga 87060 ggcggaggtt gtagtgagtc gagattacgt tattatatta tagttcgggc gatagagtga 87120 gattgtttaa aataataata atgttaataa taaataaaat aataataata aaataataaa 87180 agtaaggatt tgaataaata tttgtatatt tatgtttgta gtagttttat ttttaattgt 87240 ttaaatgtgg aaggaatgga tatataaagt gtgtgtatat atagtggaat attatttagt 87300 ttttaaaagg aacggaattt tgttattata tgtgaatttt gaataatgaa ttttgaagat 87360 tttatgttac gtaagtttgt tttataagga taaatattgt atgattttat ttatgtgaag 87420 ttaaatttat agagaaattg gaatgacggt tgttagtagt taggggaagg aaggatgggg 87480 agttattgtt taatgaggat agagttttag tttgggaagt tggaagaagt ttcggaggtg 87540 gatggtgttg atgggtgtat aatgtgaatg tatttaatgt tattaatatg gaaatttggt 87600 taaaatggta aatttgtttt ttttgttttt gttttttttt tttttgagac ggagtttcgt 87660 tttgtcgttt aggttggagt gtattggcgt gattttggtt tattgtaatt ttcgtttttt 87720 aggtttaggc gattttcgtg ttttagtttt ttagagagtt gggattatag gcgtttgtta 87780 ttacgttcgg ttgatttttg tatttttagt agagataggg ttttattatg ttggttaggt 87840 tggttttgaa tttttgattt taggtgattt atttattttg gttttttaaa gtgttgggat 87900 tataggcgtg agttatggtg gttggttaaa aatggtaaat tttatattat atatatttta 87960 ttatagtaaa aatgtattgt tttattagaa aaatgataga tttttataat atgaattaaa 88020 ttataagtta tgaaggaaaa attaagtaaa atattaaaaa attatttata agtaattata 88080 tttaaaataa aagataataa atatataatt tttattattt tttaggtttt ttgtaatatt 88140 taattattgt ttgttttgtt gcggttatgt ttttgaggtt gtatttgtat gatagaaata 88200 ttatattcgt ggtgattaaa tatttttttt tagttttatt tttaatgatg ttatatagat 88260 aatttgaaat tggtcggttg ggtacgatgg tttatgtttg taattttagt attttgggag 88320 gttaaggtag gtagattatt tgagtttaaa attagtttgg ttagtagggt gaatttttat 88380 ttttagtaaa aatataaaaa ttagttagga gtggtggcgg gtgtttgtaa ttcgagttat 88440 ttgggaggtt gaggtaggag aattatttga atttgggagg tggagtttgt agtgagttag 88500 gattgtttta ttgtatttta gatcgggtga tagagtgaga ttttgttaaa aaagaaaaga 88560 aaagaaagaa attggttaag gtaggaatat tgatattata ggaataggta agcgttataa 88620 atcgggaaat tgagtgttgt tgtttttgtt ggttttaggt ggtcggttgt tgatcgttaa 88680 ttggtatatt attggaggag ggaggtttag attgattcgt agagagatta gaggtagaaa 88740 cgtattatgg tttggatgtt gagggtgagg gaaagagagg agttaatagt ggtgttcgga 88800 gatttggttt gagtaattag gtggatggta gtatcgtttt ttaagatgag gggttgtggg 88860 aatttgaggg gttgtggaag gttttgttat tgacggattt agggttcggt agttttggga 88920 ggtttatttt gtgttaggtt acgtagagat aagattattt gggttttgtt tttgggaagt 88980 ttttgtttat gaggatatag tttgttattt aatggggtgt ttcgtttgga gttttagtgt 89040 tgttgggaga aagtttttta ttttttttcg tttttcgagt tttttttgtt tttttgttag 89100 ttgagttttt ttatggaggt tgtgtttgga ggggggttat ggatatggat gtgtgcgtta 89160 aacgttgttt tttcgtggat ttttttttta tttcgttttt acgttttgta agttttattt 89220 tttcggggtt tgatttgtgg ggtttttttt tagatttgtt tttttttatt tttagaaagg 89280 cgtgtagggg ttttttatgg tttttttttt tgtttttatt tttttttttt tgggatagtg 89340 atttgttgga cgggtgggtt atttataggg tttgtgattg tttagatatt tttgttgtat 89400 gaagttttga ttttaaggta tgatgtagat gggaataagg tacgagtttt ttttggttgt 89460 tgtaataatt gtcgaaattg ggtggtttat agtaagggga atgtgttttt ttatagtttt 89520 ggaggttaga agtttgaaat taaggtgtta gtagggttag ttttttttga agattttagg 89580 ggaaaatttt tttttgtttt ttttagtttt tggtggtttt aggtgttttt tggtttgtgg 89640 ttgtattatt tcggtttttg tttttgtttt tataaggttt ttttttgtgt ttttgtattt 89700 ttttttttgt tttttagaag gatatagtat tgaatttagg gtttatttta ttttgagatt 89760 tttgtttaaa ttttttttgt agagattttt aaatagaatt aggttatatt tgaggtttta 89820 agtgggtata tttttgtttt gggggggatt atcggtttat tgtaggtttc gttgtgtatt 89880 gaagacgtag gcggtttttt tggttaggtt tgtagtcggt tttgtttttt tttgtgatcg 89940 tggaagaatg tattttgttg gatgtatagg tttttatagt ttttttgttt ttgttaaatt 90000 ttagtttagt tttttttttg ttgtcggcgt gtattttttt tgtttagtgt tttttttggg 90060 attgtgtgtt taggttttga ggttttagaa aaggggggtg gagggttttt ttattatttt 90120 gtagtaatga ggttttatta aaattttgga gttttagatt ggatttagtt tttagttatg 90180 attaaaggat agttcgggat atgattaaag ggttagagaa agatgattta ggttgagaaa 90240 gaggaggtta aggagtaatt ggattgtttt tgaatgtgga aaaggtaatt atgatttgaa 90300 gggtggtgtt tagttgtttt ttattttttt tgaggatagg aaaaaaaagg aaataaatga 90360 tgtataatta gagtagttgg ttagatacga gggtgaattt tttggttggg agtatggtta 90420 agttttgatt tgggtttttt gaaagagttc ggggaatttt tttatttgga ggtttttagg 90480 tttggttatg tggttttgag tgattatatt gaaggggtag tggttggggt tggagtcggt 90540 gggttttgag tatagttacg aaggtatgcg tattttttgg ttgttttttt gttattgttt 90600 tttgggtttt tattttggtg aggcgtgtat tttggcggcg ttttttaggg aattaaatat 90660 gtttgttgta ttgtgcgtgg agatggagaa tgtataattg gttgattttg tgttaatttg 90720 gtggaatttt atgttagttt tgggaaagaa taattgtatg ggtgtgttta tatttattag 90780 gtgtttttta gaaaaatatt cgagaataat gttgtggttt aggatggttg ttgtgtcgga 90840 ttcggtattt ttttaggggg gttgtgttgt tgggttgagt tttttaggta ttggattttt 90900 aaatttttaa atacggcgtg gataggtggt ttagtagggg ttggattatt cgataggttt 90960 aggtgttgga gtttagataa gatatatttt ggtttggcgt ggaagatacg gggtgttatt 91020 aatggtagta atggttgtat ttttgaaatt cgggttttta ggtcgacgag ggtgtgtacg 91080 tatttgaaat gtttgtggtt ttgtagtttt tatgtttata aatttatttg gttgaaaata 91140 gtttaaaata tttaaagtat gagggaggga gtgtttgttt tttttaaaaa ggaaggattt 91200 gattttattt atttaaaaag ttatttaaat ttagaatatt tttcgtaaga gattttttgt 91260 ttttcgtttt tttagaatgg ttggagagtt ttagtatttt tgtatatttg ggatatttta 91320 gagggggtgg ggaggggtaa gtgggtagcg agcgatttta gatttaggat gagttgttag 91380 gcgtttttcg gttatatatt taagggatcg gagtgtagtt gtagcgttgc ggtttgttgt 91440 ttcgggggtg ggggtgttgt tttatgttgt gaatttttat atggtttttg attttgggta 91500 gaggtcgagg gtttaaggga cggggtgata gggagagtat gtaggagtgg gtttttggtt 91560 ttttagggcg agtggaagaa gcgttttttt tttttgtagg tgatagattt ggggggtttt 91620 ttttgaggat gagagtttgt tgttttttaa gttttgtgtt taatttaggt ttttaggttt 91680 attttagttt ttcggttttg tttgttttgt ggatgatata gtttaagggt agagatcgtt 91740 ggtttggagg gaaggttagg ttttaggtta gggtttagaa gggagggaga agtttttggg 91800 gtagtttttt ttttgtttat ttattgttta gttttttttt ttatattttt tttcggaaac 91860 gtttgttttt gataaggttt attttttgtt tttaggaggt ttttattgtg gaggaaggga 91920 ggcgtcgttc gtttttggtt tttttgatag tcgtgtttta ttttcgtttt gtgttttttt 91980 tttcggatag tgtttttttt agggtttatt taggagggtg tagcggtggt tttcggggcg 92040 gtggtcgtgg tgggggtgtt agttgtaggg gtgttttcgg tgggtgggag ttggtggttt 92100 ttcgttggtg ttatgggatt cgtatgttcg ttttgcgttt ttcggttttt gagtttatag 92160 gtcgggattt tgtttgttag tcgcgtgcgt tgtcgtttaa tttttgtagg cgtagagcgc 92220 gcggcggcgg tgatagagaa ttttgtttgg ttgtttaaat atagtttttt gtagaaggat 92280 tttgcgttcg gggaagggga ggaatttttt tttttttggg cgttcgtttt tttcgttatg 92340 gttcggtttt tatattcgtt tatatttggt cgtagcgggg cgttcggggg gaggggttga 92400 ggtcgcgttt ttcgtcgttt tttgggcgcg ggttaggcgg ggaggagggg ggcgtttcgg 92460 tcgtgtgttt aggattgttt tttagcggtt attcgggttt tagtttttta ggtttggttt 92520 tgataggcgg gcggagtagt tagtgcgaga tagggaggtc ggtgcgggtg cgggaatttg 92580 attcgttcgg gaggcggggg cggggcgggg gcgtagcgcg cggggagggg tcggcgttcg 92640 tttttttttt ttatttattt agttgagtta gggggtttag gggttttttc ggcggttagt 92700 tttgtattgt aggagcgcgg gcgcggcgtt ttagttagcg cgtagggttc gggtttcgtc 92760 gggggcgttt tttcgtcgtt gtttttcgcg cgattcgttg tttattagtt attatgtcgg 92820 atttcgcggt taacgcgtag ttggatggga ttatttcgga tttcgaaggt gggtgttggg 92880 ttggttgttg cggtcgcgga cgtgttggag aggattttgc gggtgggttt ggcgcgggac 92940 gggggtgcgt tgaggggaga cgggagtgcg ttgaggggag acgggatttt taatttaggc 93000 gttttttcgt tgagagcgtc gcgcgttttc ggtttcgtgt tcgcgtcgtt tacgtggggg 93060 attttgttag gggtattcgc gtagattttg cgcgttttta taggattttg tgttcgtttt 93120 gcgtattgtc gtttgggttt tttttttttt attgttgttt gtgtttgtta agcgatagcg 93180 attttttcga gggttcgcga ggttgtttcg gaatttttta ggacgtatag ttttattttg 93240 ggaaatttat cggttttttt tttttggttt ttttcggcgg ttttcgggtt tcgtttggat 93300 tcggtaacgg gatagggagg tcgtttttta ttttcgattg agtggatagt cgcgttttgt 93360 tcgggtggat agtttttttt ttttttacgt tagtttcggg gtcgttaagt tgtgtagttc 93420 gtgggtcggg agtatcgaac ggatatagtt taggtcgtgg tagggtttag agtgggatgt 93480 tttatggttt ttatttaggt ttggggatat ttttattcgt tttttagaat cgggtcgtgg 93540 gggatagaag gggtttgcgt gcgggtaggg agagtatttt ggtttttttt tgttttcggg 93600 gtttataaag tgtgttggga tttgcggggt tgttttgttt aagtttgggt ttggcgttcg 93660 cgtttttgag tttgtgagtg cgtgcgtttt tttgcgtttt tttgattgtc ggtgttgggg 93720 ttttgcgttt tgcgttcgcg ggagtaaata tagtaggcga aggggaagtt tatataatgg 93780 tttttagcgt tttggggtag ggtttttgag gggcgggttt gtttttgtcg ggatttggag 93840 ttttcgtttt tcggagaggt ttttaggttg atttgggtag agttttttgg tgggtcggga 93900 gggggaaagg ttgtgttgaa atgagtaaat tgtttaggtg ttaggttaag ttgggaggtg 93960 attagtttga ggtttttttc gttttatggt tagaattagg gttgatattt gggtgttttg 94020 agtttagttg tttatacggt ttatttgggg ttagttttat ttgagtgggg gaggcggggt 94080 tttttggggg attagaattt tggttggacg ttaagtagag tgttagtggt tgttttttag 94140 ggttgggttt gaggagggtg tggggcggcg aagggacggg agggggttgt gatttagtgg 94200 ttattggcgt tgtgtagagt gtgagttgga aatatcgtag ttattttgtt agtttagtgg 94260 tgaaagtttt tttttaggtt ttattttttt gtatttttgt tttttagagg gaggggaggt 94320 ttgggtttgt agagttggga gggtttgttg ttttcgtttt ttttttttat aatatttttt 94380 tatttggata tttttgggta tatgtttata ttggggtttt tttaggttta ttgtgtttcg 94440 ttgagttttt tgtagttttc gagtgaatgt gatttttttg tttttgtttt tttgtaattt 94500 ttttttgcga tcgttttttt aggggttttt tttgttttaa atgtttaagt ggtacgattt 94560 agtcggtttg attatttttt agtaagtttt tatggagaga ggttttgtgt tgtgtagagt 94620 tttttttttg tttgcgggat cgaggttttt gtttttagtt tttaatagaa agtgtcgggt 94680 ttttagtggg atttttgggg aagaattttc gtgttttaac gggagttttg tggcgggagg 94740 ggaggttagg gtttggggtt gtgttcgttg tatagttgtt attatttgta ttatgaaagt 94800 tgttagtgtt ttttttttgg gtttttgggt gtaattttat ttttgttttt atgtgttttt 94860 atttggagtt gtttttgcgg ttgtttttta agttagtttt gtgattttgt aatttagttt 94920 aagataatgg gtttattgag attattttgg tgtagtagtt ggtaattttt tggttttggg 94980 ggaaggtttt ttagtttcgg ggagtggggt tttaatttgt tggttttttg tgtttattag 95040 tttttttttt gtgtgttttg aatggttttg ttgggaattt tggttttaga gttattaggt 95100 ggttcgagtc gataggcgtg agagagtgtg tgtgtgtatg agtgcgtatg tgtatggggg 95160 ttgatttggg gtatggaaag gtggtttttt ttggtgttta aggagtttgg agtatagttg 95220 gagggtgtgg gggtgtgtat atgggagttg gataattttg ggtggataga tagacgtggg 95280 gaagggatga ttgaaggagg tggaggagag agtgtgattt agtttagtta ggggtgatgt 95340 ggataggtag ttttcgaatt agggtagaga aaagttatta ttagttagta ggggagaagt 95400 tagtatggag gaggcggatt ttgagggaga gtaggaattg gattgtaaga ggaaggagag 95460 ttttttggtt agtagtagtt agtagtagtg ggggaggttg gaatgagttg gttggagagg 95520 gggttggggt ataaggaggg gtttgtttgt gaagattata tgggttaggt tgcggagggt 95580 taggtatgtt cgtcgggagt gtagttggtt tacgggaagt atttggagtg gttgggaatg 95640 ggcgtaggag tagcgtcgtg ggagtatagg tttttttttc ggggcggttt atttggtgtt 95700 ttggtttttg taaggtaggt cgaaagggtg gggaggaaat tgttagtttt ttatagcgtt 95760 gggatggtgg ttttagggtt tttgaggtta gcggatgtgg gtgtttgtta ttatgtgggt 95820 tgttgagggg cggagatttt aggggttatt ttaaagtagg acgagttttg agttacggta 95880 tttttggggg tagtttttta atcgagtaga cgtttaggtt tggaattttg taatagaggt 95940 tatagggttt tgattagggt gttttgggag gtttagaatt agtggtagta tatagggtag 96000 acggtaagtg atttggtatg gggaaagagg taggtgttta ggtcggtata gtatattcgt 96060 aaggaatagg tagacgggaa gtcgttcgtg ggtttgtgtg tgtgttcgga gttaaaattt 96120 tgttaatgtt ttatgttttg ggtatattta tttttttttt ggggagtatt ttttttttta 96180 tttttttttt tttcgtttgt tttttttatt tagggttttt tttatttttt tcgttttggg 96240 gatcgagggt attatggttt tatgttttat tatcgatgag ttgtataggg atttagtttt 96300 ttcgttgttt aggtcgggtt ttttaggttt agggttttta ggaatggaga gggtattagt 96360 gttttttatg gatttaaatt tttcgtattt cgtttttgtt ttttttttaa gataggtttt 96420 cgagttttaa ggttttaggg ttttgtggag gtcgttacgt agtagtaagg agaatgtttt 96480 gtatttggtt gatgagattt ttagagtttt attttttatt tttttattgt ataaacgggt 96540 ttttaggcga ttgtagtatt cgttattgtt cgtaataggg tgataagagg gatgattttt 96600 tttttttttt tttttttggt tggtggaggt acggggttgg cggacggtat gtgttttcgt 96660 gaatttaggt taaatttgtt atcgtaaata cgattataat tcgggttttt gtgtaataaa 96720 agttttttta agtattagtt gttggtttgt tttgtttagc ggtgtttgtt gtaattagat 96780 ttgtatatcg agaaagaatt taaaagtttt tgatgtttgt tgaaataatt tggtttagga 96840 tttacgtgtt tagattttag agttgtgtgg tatttgagtt tttttcgagt ttttattgtc 96900 gttcgaggag gatttttaga tttgtgtttt ggaggtagag taggttgtgg gacgggtttt 96960 tgggtgggaa ggattatgtg gatatgtttt tttgtttgag agttttaata ttttcgggac 97020 gtgggagttg gcgcgttggt aggatttagg tgtttttttt ttttttagag aaaaaggttt 97080 cgttgtttgg taataggtgt agatttgttt ttaattaatg ttagtaggtt ttttgcgtga 97140 tgaattttgt tttttagtta agatttaagg tattttgtga atattgtttt tttgtagttt 97200 gagtttttgt ggtgggaggt aggagttatg gggagtgggg gtaggttttt tatacgggtt 97260 ttatagttat tggtagtatt gatttgatgt tttttgagtt tagagtttag ggttagatag 97320 atttattgtt tcgattacga gttggtttat ttagaggggg gcggatatag tatttaggta 97380 gtagatgtat tgtgattagt tttgtagcgg ggttgtgggt tttttgggtt ggatgttcgg 97440 gaagaggtag gtggaggtaa acgttaggat atttttgtag tgattgggtg attgtaggtt 97500 ggaaatgttt tttgtgggtt gtggttgttt aggaaggttt tgaatggggt tagtggatag 97560 agtttgtatt tagaggggta gtgttttgga ggagtgaggg gtatggtagt gtagggatgt 97620 ttaggtcgtt tttattttgt tattggaaag ttgggcggtt tcggtttttt tagttttttc 97680 gtttgttttt ttgtttgtaa agtggggtta gaaatagttt tttttgaggg ttgttggggg 97740 attttgagat gtagtttatg gcgttgagta cgggttttgt tttttacggg tgtggtgggt 97800 gtcgcggttg gtgtggtatt tgggcgggaa aagggggtat ttgtaaagga taggtaggtt 97860 tggatgttta aatatgtaga tttggggatg ggaggtttta ggtaagggtt tgtgtgatgt 97920 tattgtatga atgaggtcgg atagtatggt tattattaat tatggaaagt acggtagata 97980 ttagtgttag tagcgttcgt ttgggggttt ttttgagttc gataggtatt taggttttta 98040 gtgtagttat gggatttttt tttttttgtt tggttgatat tttggaggtt ggcgttatgt 98100 tggttgtagg ttttttttat tgggaggttg ttttggtttt ttttgttatt atttattttt 98160 atttttattt tggagtgtta tagatgggtg gattatatgt ttatttgtag ggttaagcgt 98220 tgataatgag gtgagtattt gttggatgat cggattatga ggatagcggg ggcgttggta 98280 gtttgcgttc ggttttgtag gttggttttt ttttgaaaag cggttgtggt agagtgtgta 98340 ttttagggag tggtgtttgt tgttttgaat atttttattt agtaggtttt tgtaagggtt 98400 tagttaagtg tggtgtagag ttgggttggt agttggaata gttttatttt gtttagtggt 98460 gagattaagg gttgatgggt taaggttgcg tgttgtttgt ttagttcgtg gatttattta 98520 ttgagtattt ttatattttt atattgggtt cggggtgtta ggaggtggag gggggattgg 98580 gtgtttggaa aaataagttt atcgagagtt tgagttttta ggggttagta ttaggtagtt 98640 attacggtgt tcggtatata gtggttattt ggtttcgtcg gttgttttgg tggtggagag 98700 cgtgtatggt ggtcgtacgt gatgggtatt atttagggta atatagatat gtagattgtg 98760 tatttgtttg taggagttag ggatttttta gtttggtaat ttgtgatttt tgtttattcg 98820 ttgggagaga ggtgttgttt tttgatagtt tggtgtcggg agagtagaat tagggttttt 98880 tttttttttt tttatttttt attttttata tgtttaggta ttaggggagg ttatatttag 98940 ggatgagttt tggttattgg gtttagggtt ttattgttgt tatttttttt ttttgttagt 99000 tagttaaatg ttcgtttatt atcgtgtcgg ggatggggtt ggtttgtttt tttgaagttt 99060 ttttggtgta tagtttaggt tggagtttcg gacgatttcg ttattttttt tttcgatttt 99120 ttttttttat tttgatttat tttagaaatt tagttaaaaa ttaagttttt gtgttttttt 99180 ttgataaagt tattgaggaa aaatggttaa atattgtttt tttttttaaa gtttttttgg 99240 ttttttttaa atttggaggt tttgagttgt ttatgagatt aaagggttcg gaattttttg 99300 gaatatagtt ttagaagtgg gaggatttgt tattttttta gttaaataga tttattagtt 99360 ggtttttaga tatttttagg cgtttggggt atttttgggt ttaggttgtt taatttggtt 99420 tgtagagttt cgaggtttcg tttagattgg gttagtagat agttttagag attttaagtt 99480 tgttgtcgtt tttaaaagtt ttgttaatgt ttagaaattt agagggataa gaagatgatt 99540 tcgatgttag tcgggattat aaatagtgag gttcgttttt ttttttattt atgtttgttt 99600 ttattgtttt cgtagttggg tttttagggg attgttcgtg gttatggggg aggtcgggaa 99660 tgcggggttt agattttatt gggtttttcg tatttttttg tttttttttg tttatttttt 99720 ttttcggaaa tttttgaata tttttttata gtttttggta ttttgttatt tttggtattt 99780 ttgggttaat tgggaaagtt attatttgtt taatatttag aaaattaagg ggtttggttt 99840 taaatatatt gtagtgtttt tttttttata tggtatcgaa ttttttgtgt ttttaaagtt 99900 aggagtttgt gttttggatg tgggcgatgg agttttgtag atatttggag cggttttttt 99960 gggagagttt ttttcgtttt tttatttatt cgtttttttt tttttgtttt aagttttggt 100020 tatagtttcg gaggggttat ttgagtgtag gttgttttta ggtgtatagt tggagggggg 100080 tagttatttt atattttttt gtttgttagg ggtattttta gggatttagg ttttgaggga 100140 tagcggaagg gtggggtggg gagtaggtcg ttgtttcgtg ttatttgggt gttatgtaga 100200 ttttgaatgg gtagtttttg ggagttggtt tttttttttt atttttttta tagtgttgtt 100260 tttttgaggg gttggagttt tttggagttt tttgtagttt gtggtaggtt tttttgattt 100320 tgtgtttggt ttcgtagttt ttaatttata gttagtggta tgaagaatat ttttggttgt 100380 ttttatttgt ggtttttgta ggtagtagtt ttttggggta gggtttgggg gttttggtat 100440 ttttttgtgg gattttttgg gtatgaggga gggagttatt tgggttatag atagattttt 100500 tttttgtatt taggaggttt aggatggatt tgttttattt ttttttttgg tgggaagaga 100560 gtatttttgg ttatggggaa tgtggtttgg atagagttat ttagtttttt ttttttttta 100620 ggtagggttt tgaaagatgg agatggtttt gtttttgtta ggttaatagt tagtagtttg 100680 gtggattttt atgtagttta ggtaggattt ttttttgttt ttatttttta ttttatgtgt 100740 aggaagttgg ttttaagtag ggatttttgg tttcgttttt tacgtgggtg ggtagttttt 100800 ttgcgagggg taggttaggt ttttgtttta tgttttttag agatcgatgt tatttatagt 100860 aagagtatat aagttttttt ggttttaaat taggtttgga ggggtggttt ttttttttgt 100920 tttttgtttt ttgtttttta ttaaaggtta gggaatggag tgttttgtat gtttgttggg 100980 gttgggtttt tttttttggt ttaaaatgaa gggttggaat ttttggtgta gattgtacgg 101040 tgagaggtgt tttttgggat ttattcgagg agtattattg ttgaatgttt tgttaggtta 101100 ggagtatcgt tgggggtggg agaggtagtt ggtttatttg tttatttaat agttatttat 101160 gggtatttta agggttagtt ttgttttagg tattgggggt ttaggtatgg gtttaggaga 101220 aggggtagaa cgggagggtt ttttggagga aggtttttta attagagatc ggggtaggag 101280 tttgttaggt aggtgatgtt ggttagtttt ttttgttatt tttttttttt tttttttttt 101340 tttttttttt tttttttttt gagatagagt ttcgtttttg ttgtttaggt tgtagtgtag 101400 tggcgtgatt tcggtttatt gtatttttcg ttttttgggt ttaagcgatt tttttgtttt 101460 agttttttga gtagttgaga ttttaggtac gtattattac gtttagttaa ttttttgtat 101520 ttttagtaga gataaggttt tattttgttg gttaggttgg ttttaaattt tttattttag 101580 gtgattcgtt tattttggtt ttttaaagtg ttgggattat aggtgtgagt tattgcgttc 101640 ggtttttttt tgttattttt gtagatttat agtgtgtgtg gaagattgta tgtttgtgtt 101700 tggtatagtt gttttcggta tttaggtggg aggtggggga gagggttgtt ggtgttagta 101760 taggttatgg tatgagatag gttttcgtag ttaagcgggg tgtatcgtag tattggaggg 101820 gttttgttgc gtacgagatt taggttttgt atttgttttt ttttttagga ggtttggagg 101880 gttgggaggg attagggtgg tgaaataatt taggtgggag agaggtattg ttggagaggt 101940 agagggagtt gtaggtttgt agtagcgagt tttaaatttt gggtttttat tagaaaattt 102000 tagaaagggt tgttttgttt ttttttttaa attataaaag aaatttttgg tcgtttgggt 102060 tttttggggt cgggtggggg aggagatttt ttattcgtat ttttgtaggt ttagtattgt 102120 gtagagggag gagggtggag gtaaaggcga gggaggaggg tggaagtaaa ggcggggttt 102180 ttttttagtt tcgttgtttt gtttggttgt tgtttttaga tttttatttt tggttcggaa 102240 atatggaatt ttgggatagt tggggtaggg ggtatagaac ggagattttg gtgagggagg 102300 aatttttttt ttagttttgg ttgtggttat agtaaggtta ggttgggagg attttattta 102360 aatatttata ttttttttaa tatttaaatg atgaagtagg tttttgtata tagttgtttt 102420 ggagttagtt gttgtttgtt ttattttttt tttttttttt tttttttttt tttttttttt 102480 tttttttttt tttttttttt tttttttttt ttttttttgt attttttgtt tttgatttaa 102540 gtttaggttt ttttagttgt ttttttttta tttataggta ttttttgtga ttgagttttt 102600 ttttgttatt ttttataatt atttttttta attgagtatt ttttaggtgt taggttttgg 102660 gttggtattt tgtatataag gtgtttttta atttttacga gagtttaata aggtagattg 102720 ggttgttgag gttttagcgt tggaaggtcg gttcgggttt ttttagttcg tatttgtatt 102780 tatttattat ttttttattg tggagatttg ttttttggtt tttggttgag tacgatggaa 102840 atttttgttt attagttttt ggagagtggg gatggttgag ggtttcgatt ttggggtttg 102900 acgggggttg tttttgtttt attttagttt ggttgttttt ttatttaatg attgagtttg 102960 taaaattaga ataatagtgt tatttggttg gtattttggg tggttgggag gcgtgggaga 103020 gggtgtacgg aggggttgag cgaggtgtta gtatcgtggg gattttcgag ggtagttttt 103080 ttaggtttag ggcggagtgt aggtagaggg cgcgatggtt tagcgtgtcg gtttatattt 103140 ggttttgttt ttgtttatac ggtaatgtgg gggagttatt agttttttag tgttttagtt 103200 ttttatttgt gtaatgggga taagagtaaa ttattgtttt taggtatggt aagtatttat 103260 atatattgat tattgtagaa tgaatatagt gagttttttt taggttttta ttatatgtta 103320 ggtagggtgt taggttttag tggagagggg ataatgatgg gtaagttggt ttttgttttt 103380 aagggttgtc gagtagggag gaaggcggcg gttgttttga ttgtgattcg gagtggggtg 103440 attcgtaaag aggttggcgg gaggttggtt gggggttggt tgggggttgt tttttttttt 103500 gtttgtgttt cgtggtaggg tattaaattg gtttttttta tggattttcg aggttttgat 103560 tgtgggattt cgggtaggtt ttgggatttt gtgattttgt tttcgtttgt tatttaggtt 103620 tttgttttta gtagtgttta gtatacggcg atttttgtat gttttttagt gtgtgattga 103680 ttttggagtt gagatttggt agttgaggtt ggatattgtt tttggataat tttcggggag 103740 gtgggggtag ggtggggttg tgagttggta atttcgagtt tttagtagtt ttcgaatgga 103800 ggtttttttt ttgtaggatt ttcggggagg aaggagggga tgggggagat gaggtttgtg 103860 agtttttagg agggtagagg tttatatttg tagcgtttta gaaatatttc ggggtgttta 103920 ggtttattta gtttttttga gttagaatta ttaagagttg gggattagta gtttattttt 103980 tagtaagatt tagaaatgat ttttttgaat agttcgagtt aagaatgata tatttggaat 104040 tagaatatta gaattataga ggaatcgaga gaacgggttt aaaatgtgta gggattttag 104100 ttatatggcg ttatatggag gaaagtattt aatattatta ttgtatgaat ttgtttaaat 104160 atatatatat atatatatat atatatatat atatatatat atatttttta gtaaagagtg 104220 gaaagatatt tgttagaata ttgatggaag ttatttgggt tgtgggttta tagatttttt 104280 ttttttgttt ttgtgtattt tgtaaatttt cggttttgtg tttaaatttt ttttatagtt 104340 aggaataaag taatagatgt tattttttaa agtttatggg ttcgtgttcg taattttaat 104400 attttgggag gttgaggtag gaggattttt taagtttagg agtttgagat tagtttgggt 104460 aatataggga gatttttatt tttttttttt tttttttttg atagagtttt attgtgtttt 104520 aggttgaagt ggcggtggta cgtttttggt ttattgtaat ttttgttttt taggtttagg 104580 tgatttttat gttttagttt tttgagtagt tggattatag atatttatat ttgtaggatt 104640 tgagaatttt ataagaggaa agtttttatt cggaggttgt tggggatttg gagttgttag 104700 tttatatatt ttttagtaga gatagggttt tattatgttg attaggttgg ttttaaattt 104760 ttgtttttaa gtgatttatt tatttcggtt ttttaaggtt ttaggattat aggcgtgagt 104820 tattgcgttc ggttatggga gatttttttt taaaataaga ataaaaataa aaataaataa 104880 aagtttattg ttaaaaagaa aaatatatta tttaatttaa ttttttttta ggattgagag 104940 atgaggaagt agaggtcgga aagtgttata ttttttggtc gttggtagtt aggggatttg 105000 aggtttgggt tggttttttc gtgttttagg tttggggtgt taggtggagt ttttgttttg 105060 tttaaaggtt taggtgtttt tgttagtatt gtttgttttt gtatttttgg ttataaggaa 105120 tgtgggttaa aggtagggtt tttgattttt gtttaggagg gtgaagtggg ttggtttttt 105180 ttgtttttgt tttaaggttt ttgcggttgt gtttttggaa attgttggtt cgagttagtg 105240 tgcggagttg ggatagattt tatcgtggtt ttcgtggggt tattttatgt tcgggttgga 105300 agggattttt cggtttagtt ttttttgttt tttattagga aattgagatt agagaggtta 105360 tttgtttggt tcggggtggg gtgtagatgg cgtttgtgat ttttgtatgt tacgtgtaga 105420 tagtttttta gttgtgggtt ttttacgtaa gtagttatgt tggggataat ttggttgaaa 105480 tttgcgattt aatgaagaga agaatgattt tttttgtagt tttgtgtttt ataggttttt 105540 ttttgttttt attttttttg tagaggggtt ttatgttggt gggtgggttt ttgttgttgt 105600 aatgggttta ggtagttttt gggtagtgga ggtttggttg tttttttgtt taatgttttt 105660 tgtagtttac gttgttcggg aagggcgggg aagtatttag ttattgggga ttttataaga 105720 tgggtatttg ggagatgttg attggtaggt taggttttcg tggtttatag gtaggttaga 105780 ggttatagtg ttgagttggg ttgagttggt agtttagggt agtgggggtg ggggtatttt 105840 gtttagttat gggttttttt ggtataaggg tttggagttt attgtaaata atttttttag 105900 tttttttttt ttttataggt tattagtaga attgaggggt tttttgttga tgaggtgtgg 105960 tttgggaggg gttagttgtt tgtttatttg atttttgcgg ataggtgatt ataggttttt 106020 tgttttaggg ggttggggga aagatcgggg aggttttttt ggttttttta tttggaagga 106080 aaatacgggt ataggggaga tattttatag ggatatattt tagttagtat tttttggttg 106140 tgttgggggt atagtgtttg ttttgtttat aagaggggtt agtttttttt aggatttaat 106200 tttagttttt agtgtagggt agatgagtat ttagaggttt agaggattta tattacgaga 106260 gagaagttgt gattatatag gtattgaagg ttaagtagaa gagtgggata tacgggtgat 106320 ttgaaagttt tagggttagt gtggttagtt ttagatagtt ggggagtttt gggtattagg 106380 tttagtaggg gaggagggtt ttcgtgatag tttgttgggg ttgttgtaat aaagttttac 106440 gaattttggg ggttgaagat ggttttagag gttagaagtt taaaattaag gtgtcgatta 106500 ggttgatttt ttggggtttt tgcgggaggt ttcggtttag gttttttttt tagtttttgg 106560 tggttttcgg gtgtttttgg gtatgtagat gcgttacgtt attttttgtt tcgtttttat 106620 atggtttttt ttttgtgttt ttgtgtttcg taaggatgtt tgttattgta tttagagttt 106680 attttaaatt taggatattt tttttttgag attttttatt gtatttgtaa agattttatt 106740 ttaatttttg ttatatttat aggttcgagg gttagggttt tggtatgttt tttgggggtt 106800 attatttagt ttattgcggt agttgatttt aggggaagta gaatgtttta agtttggggt 106860 gagcggaggg aacgttgttg ggtggggagt gggagattag gttcggagat atcgcggatt 106920 ttttttgttt gatgagggcg tgatgaggtt tttattttag gttttttgaa tggcggttgt 106980 ttttgaggag attttttttt ttggatttgt ttttttagaa atttttattt aggtttaggt 107040 tttaaggtgg atggtaagag gcggttgttt ttgttatatt tgatgggtga gtgtgtgaac 107100 ggggttggga gtaggatatt tgttattttt gtggatagat tttagaggtt tatgaatttg 107160 ttgttgggga aggtgtttga tttagtttga ttttttattt ttattttttt tttttcgttt 107220 ttttttatta gttttgtttt tagagtttta tttttttaaa ggtaggcgtc gttttttgga 107280 ttttttagta gttatttttt attttagatt ttttttttgt aggttttttt ggttttagcg 107340 tttatttttt tttgggtttt tgttttttta tcgtgaggtt tttgggtaga agtgtggggt 107400 tttttcgttg tgtttggttt tcgcggtata ttaggggttt ttttaggggt tcgttttgtt 107460 cgttaggttt ttagggagtt ttttaagttt ttagatgggt ttgatggagt tttttaatgc 107520 gttgttttag agtaggaggg gtttcggttg agttcgagag tttttttagt tatattttgg 107580 gttgtttggg gtagttaggt agttcgtttt ttggaggtgt tgtttttttt tggttatttt 107640 ttttggaatt ttttgcgttt agttgcggtt ttttttatat agtatattta ttattttttt 107700 ttatttgtga tttttttttg ttaatttttt tatgtttttg agaatggaga ttaggttttt 107760 tttattttgg agtttagtag aatttaaatt aggtagattc gtgtaggttt acgtgggggt 107820 tttgtggtta ttgtggtttt gtcgttattt ttagtttagt ttggcgcgtt ttggattatg 107880 ttatttagtg tcggtttttt aaattttttt tttggttttg taggtttggg aagtagttgg 107940 tttttgggtg tagttgtgat cggagtttga attttgtttt ttggggttat cgttttttgt 108000 aattaggttg tagtttatat tggttcgggt agaggttatc ggttgttcgt tttggggtta 108060 taatatagag agtttcgtga ttaatggagg ttttatttgg gttaagtggt ttttggtgtt 108120 aggcgttttt tttttttttt tttttttttt gtatttttta agtgtttgta atattttttt 108180 taatggataa tgagacgagg agggagggag gggtggtttt tttgtttagg tagattagga 108240 atggttatcg tttgtgtgtg tagtgatagg tttgggaata gataagggag agtttgttcg 108300 ggaggttgga tttttatatc gatgttgttt gtgtttggta gttttgtttc gggttttaga 108360 atagatattg attaatacgt tttttagggt ttttaggttc gggttttggt tttcggtaga 108420 gttttttatt tatgggaaga agtatcgagt agttttgttg gtttttcgta gggagttggg 108480 atgtattttt aagagtagta tgcgtgaagt tcggggtttg ggtaaaggag tgtttgggga 108540 agagtttgtt gttgttggag ggtcggaagt agaggggaag gaggggtacg cggtaggttg 108600 aggaggtggt tggcgatttt gtggtgggga cgagggggtt atgagtagat taggagttag 108660 tattacgttt ttttgttttt agaatcgagg acggagagtt gttagagagg ttttggcggg 108720 gtgtttgggg ttatttaaag ggcgtgggtg gattaaagtt gaggaaagtt ttattttggg 108780 ggatttcgta tttaattttt gaggttttta gagttgtagt ttgtggtttt tcgaagttaa 108840 ttatttttta gggtttcgtt tttgttttta gcgatagtta tttattaggg agtttttgat 108900 ttaaggagat ttgaaaggtt atttggtttt ttttttattt ttaggtaggt tatatttaga 108960 tttttttata tagattcgtt ttattttttt gttgtttttt attagggacg gagggtgggc 109020 ggttttttta tttaggtttt ggcggtttta ttttagttag gaaatttttt ttttttattt 109080 gttttatatt tttttttttg cggttttcgt ttattttttt ttaatttgtt tttagtggag 109140 tagttagtag ttggtttaga attcgggggt ggggggagcg ttagattagt gtagtatatt 109200 tgagagtgtg ttagaggtgt ttttattttt atagttgatt tagtaaagaa aagaggaagt 109260 ttagtaattt agcgttattt taaagttcgt ttggaatgat tttgtggttg tcggaattag 109320 gggtacgcgg tagatgacgg gagtaggtat agagaggttt tcgtttcgga ttagtcgttg 109380 ttgttttttt ggaggttggg ttgtttttta agaagaggat ttaaggtttt gtgagcggtg 109440 gttttttttg gagtttttat tgtggttttg gttttgtttt gcgtaaagag agatggtttg 109500 aagtagaagt tgttacgtgg ttgttttagg taggcgttcg tagttttagt tattcgggag 109560 gcggaggtag gagaatggta tgaattcggg aggcggagtt tgtagtgagt agagatggta 109620 ttattgtatc gtagtttggg cgatagagta agatttcgtt ttaaaaaaaa aaaaaaaaaa 109680 aaggagtaga gaaatttttt ttagaaggtt tgtagttatt ttttttttat gttttagagg 109740 taaaaaaaaa aaaaattgta tatttcgttt tttttttttt tttttgagac ggagtttcgt 109800 tttgtcgttt aggttggagt gtagtggcgc gatttcggtt cgttgtaagt ttcgtttttc 109860 gggtttacgt tatttttttg ttttagtttt tcgagtagtt gggattatag gcgttcgtta 109920 ttacgttcgg ttaatttttt gtgtttttag tagagacggg gttttattgt gttagttagg 109980 atggtttcga ttttttgatt tcgtgatttg ttcgtttttg ttttttaaag tgttgggatt 110040 ataggcgtga gtcgtcgcgt tcggttatac gtttttgttt ttgaataggt ggttttttga 110100 ttttgggtgt ggttatttta agattttgtt ttggtggggt ataattttgg ttttaggtag 110160 ggcgatcgta taatttattg ttttttgggg gatacgttag tgaaagggat ttttgaatga 110220 ttacggtggg ataatagatg tgagttgggt ttgttttagg aaggttggat gtatgggttt 110280 tttgagttag aggagataat agtagaaagt tttgcggttg atgggatcga gtaggagaag 110340 ggtcggcgga ggttggggta ataacgtatt tgtttattgt gaagggtttg tgtgagttga 110400 tggttgatga gagggtagtg gggcgaggtt gttttttgtt aggttagatt agttttagga 110460 tatttatatt ttttttttag aatcggtgat ttagtggtta gaaggggttt tagaattgac 110520 gggatattga gggagtcgaa tggaatggtt ggagtggtta tagtaggttt taggtttttt 110580 ttcgtttttt ttttgtgttt tgtttttggg gtttatattt tggggttgtt gtaatagagt 110640 gttataattt gggggtttat aaatatagtt ttcggcggtt tttggagatt tttggcgttt 110700 tttggtttgt agacgtatta ttattatttt tgatttttgg tttttgtttt tacgtggttt 110760 tttttttttg tttgtgtgtt tttttttttt tttgtttttt ataaagatgt ttattattgg 110820 atttagggtt tattaaattt agaatgattt tattttgaga tttttatttt aattatattt 110880 gtaaagattc gttttttaaa tgtgattatg ttcgtaggtt ttaggagtta ggatttaaga 110940 tatatcgttt tgggggatat tgttgaattt attatattta ataaatttag agttggtgtt 111000 aatgtttttt gcggatatta tagtagattt tggaggtttt ttgtaaagga attcgtagga 111060 tttttttttt tttttggagg gatgagattg tagttgggtt ggggaaagtt gttggtttaa 111120 gttggggttg gtttagttgg tgttggtttg ttaggttgtt agagagtttt atttagggag 111180 aaattaatat tataaagttg ggggataaga gaaggtttgg aattttaagg gttggttgtt 111240 gaggttagtt gtttattttt ttgtgtttta ttttataggg atttaggttt gttagtgttt 111300 cgtttttgga aggaatgttg tgggttgttg tgttttatag gtagggtgga gggttttttt 111360 gtagttagcg agttgttttt tttgtagcgt gtagagggaa ggaggaggtt tgtttatttt 111420 ttttggtttt agtcgaaaat ttaattatag gttttggtat taggtagatt tgtttatttt 111480 tatattatta ttgtagagtg agttaggttt tttgggtggg gttgtgatga gtaggaagga 111540 ttttcggagt gtttgggatt ttttgggttt agggttgtta gaggtagaga gaaagaagtt 111600 tttttttaat atttgagtaa agatagttat tagaatttat tagagtggtt ttttgtggtt 111660 tttttttggg tgttgatttt tttggtgtat ttgaagtttt tagggatatt attgacgttt 111720 tttgtatttt tatttagggg ttagtggaaa tggttttttt tttttttgtt tagaggtatt 111780 gtggatgatg attttaggtt ttagatttta gttattgggt tacgtgtgta gataagtttg 111840 ggtagttagt aatttttggt tattaagttg gttttttgcg gattgggtcg gtattggagg 111900 cgggttttag ttgttagtat tgtggtttag ttaggtttgg ttttgggaag gtagaggggg 111960 aggggattgg gaaagggatt gagttggggg tggggtggta ttttggtttt ttttttttag 112020 atttttggta ggtttgaatt atttggttgc ggttttttaa ggagggagcg tttttttcgt 112080 tttgatgtgg attttgtttt ttgtttacgt tgtttttgtt tttaaataaa tgtggttttt 112140 tgtggggagt ttgggggtcg ttttttattg atattgttgt tttttggttt ttttttgtag 112200 gtttcgttta gttttattgc gtttattttt aagttttttt ttttggacgg ttttgttttt 112260 tgagaatata ttttttttta ttattttaat tgtgtttttt tttttattcg gagtttgttt 112320 tatttgtttt aggagttatt tttttttttt attaagtagt ttaggttaat tttggagggt 112380 taatttgtgt ttttttagaa gtaggttttg agatagggat tttagtggga ggggatatta 112440 ggggatgttt gagtgtggga atgggttagg tagggaattt agttaataaa gggtgtttta 112500 ttagtttatt gtgattatag gtggttgttt agtttttata tcgggtagta tggggagatt 112560 gtagatcgtg tttttagttt tgttttattt ggggttgggt aagggagttg gggtttttat 112620 attttagttt ttggttaagg attgtattgt ttattttttt tagtttttcg agggtttggg 112680 tattaggaaa ggttttgggt ggagatacgg aaataggtta tgtgaagtta gtgggcgtga 112740 ttggtagtag taaggttagg atagttttgg ttattagtaa ggtgattata tattttagta 112800 tgtatagttt ttatagatat atatttagga gatggtaatt atattagtaa tagttatttt 112860 tgtcgcgtgt tatgtttgta tttagggaat tttatttttt atttatttat ttatttttat 112920 ttgagatgga gttgcgtttt tgttgtttag gatagagtgt aatggtataa tttcggttta 112980 ttataatttt cgttttttgg gtttaagtta ttttgtttta gtttttcgag tagttgggat 113040 tataggtatg tattattacg tttgattatt tttgtatttt tagtagagat ggggtttttt 113100 tattttggtt aggttggttt cgaatttttg attttaggtg atttatttat tttagttttt 113160 taaagtgtta ggattatagg tatgagttat cgcgtttggt tttaggggta ttttattatt 113220 ttattatttt ttatagtagg tgatattgag gatattgagg tttagagtag attgtggtta 113280 tgttattttt ttgtttggtt tttttgtttt tagttttgaa ataaagagta cggtttttgt 113340 gtaggtttat acgttttgtt tttagttttg gagtagtttt taagtttttt gaaggtatat 113400 taggtttttg ggtttcgttt tttaagtttt ggataaatag gaggtgaagg agtttttgta 113460 attggatttt attttgttag cgttaaggtt ttgtttgatt atttatttta ttttatatag 113520 attagggatt tgtgttaagg tttagtgtta taggagagtg aagataagga ggtgtttatg 113580 gcgtatatgt tgttggattt attttgtaga ttttaagggt tatggggagt tatttgttag 113640 gtgaggtttt ttcgtggttt ttttttgtag gtttagggta gtatataggg aggtgttttt 113700 ttattttttg gtattatttg ttcggttttt ttgagttttg attttggttt ttagatagtt 113760 agtgtttttt tagggataga atttgttttg ttgttgttta gaggagattt agtttgatta 113820 gggttagcgt ttttggaatt tgagtttgga attttatttt gttttgggta gaggttacgt 113880 tgtttttttt tacgagagtt gagttgcgta tgagattatt ttgattttgg gttttattat 113940 ttttttgtat gatatttgtt ttaggttgga gtagggtttt gtggttcgtt tggtgttttt 114000 tttttagatt gaggtttgat atgtatatta ggaagtgttt gatttggttt taggagttgg 114060 gagcggtttg ttaggtagtt tgtggttaga gtaggggttt taataatggt tttttgtgcg 114120 gtatattttt ttttaaatag gtttaggttt aggttgtttt tgtttcgatt tcgttatggg 114180 tttggagggg aaagtttgta tttggagggt ggtttattgt ggtttttttt tgtgtagtag 114240 ttgagatcgt aggtgtttga gaataggaga agttttgtgt ttattttggg ttgtgagatg 114300 tttttttaga ggtggggatg gggatgggtt agtatgtagt tatttatatt ttttagtttg 114360 ttggtattaa ggtttgtgta tgtgtgtgtt tttttttttt taattttgtt tttttaatat 114420 ggagttttgt tatttgttta ggttggtttc ggatttttgg tttaagcgat tttttagttt 114480 taggttttta aagtgttggg attataggtg tgagttatta tgtttagtta gtattaaggt 114540 gtgtttttta agagtaatat tggtcgggtg tagtggttta cgtttgtaat cgtagtattt 114600 tgggaggtcg aggtaggcgg attatgaggt tagtagattg agattatttt ggttaatacg 114660 gtgaaatcgt gtttttatta aaaatataaa aaaattagtt agacgtggtg gtcgggtatt 114720 tgtagtttta gttattcggg aggttgaggt aggagaatgg cgtgaatttg ggaggtggag 114780 tttgcggtga gtcgagattg cgttattgta ttttagtttg ggcgatagag cgagattgtt 114840 ttaaaaaaaa aaaaaaaaaa gaataatatc gatggtttta ttttttgaat atgttaagtg 114900 atttttatgt agtataagta ttttagaagg taggaaaatg taatgaataa tatttatcgt 114960 tatttatttt atttagagat cgttattttt tgttcgggtg tgagtgtgtg tgtgcgtgta 115020 aattgtatat gtgtgtatga aatggaatta ggatttttgt atatattttg tgttttgtta 115080 tttttattta atattttcgg tattttttat ttttaaaaat gtgattttaa tgatggtgta 115140 ggtttttgat atatgggttt agaaaatttg cggaaattcg gattgttttt aggttttgtt 115200 agtttaatgt tgatgtaaat gttttcgtac gtaaattttt ttgtattttt gattattttt 115260 ttgggataaa tttttagaag tgggttaaag tatatgaacg gtttttaggt ttttggagta 115320 agttgagatc ggtggggatt ggagaaggga tttagggagg tttttgggag tttgcgagat 115380 tggagtttgg ttttagggga tttgaattta tagatgaagg agatggttgg taaaggtggg 115440 aattttttgt tttatgggtg ggggggtgat attgttttat tttttagtga tagtatgggg 115500 atttttttaa tatgatttgg tttcgtattt ttttgatatt gtgtacggtt tatagttgtg 115560 atgtttagtt gggagttttt tttgtgtttt ttagttgtat taattttttg tagatagagg 115620 aggaagttgt tcggtgtttt tttttgttgc gtgggttttt tgaatttgtt tagttgggtt 115680 tgtggatttg tgtagttacg tacggggttt taaaatttgt aaaatgataa gtttacgaat 115740 attttcgttt ttgtgggtga atgtggatat tttttggttg cgtttttttt tatagggaag 115800 atggagacgt gtaaagtgat aaggatttgt tatttttggg taggttatgt cggttttatt 115860 gtgaggatgg tggtaggggg ttttttagga ggtttgtata ttgggaagag aggggcgatc 115920 gtgtgtgatt gtaggattta gggcgtagtt ttaggatttt gatgggggag gagatgttgg 115980 ggagttttgt tttgttagtt tggtgataga tattttttaa tgtttttcgg ttgggtataa 116040 tttataatgt ttttcgtggg gaggtaattg tttatgaggt atttttggta gggatgattt 116100 tgttttattg ttatatattt tagtaatgaa ataagaattt agagtgatgt gattttttcg 116160 atgatttttt taattatttg gggtttttgt gcgattttaa gaagggggaa ggaggtagtt 116220 ttcgtttttt tgggtttttg atgtggtagt tttggaatgg ttacgtgttc gttggtttat 116280 agtgggttat ttgtcgaatg tggttgtggt gggattgggg ttgggttgga gagtgggtga 116340 ttatattagt tagttttatt ttgggttatt gtgtagttag gggttttatt tttttagggg 116400 tttcgttgtg agtgttttgg ggttgttgga ataaattatt ggaaattaag tggtttaata 116460 aagattgatt cgtttatggt tttggaggtt ataagtttga tattaaggta ttggtaggat 116520 tatatttttt tcgatagttc gaggggagga tttttttttg ttttttttag tttgcgttgg 116580 tttaggcgtt ttttggtttt ggtagtattt gtagtttttg tttttattac gtagtttttt 116640 ttatcgtgtt tttttgtgtt ttaagttttt ttttgttttt tttttataag gatatcgagt 116700 attggattta gagtttattt taaatttagg atagttttat ttcgggattt ttaattatat 116760 ttgtaaagat ttttttttta aataaggtta tattcgtggg tttttggggt taggtattag 116820 atatgttttt ttgggggtta ttagttaatt ttttatagaa ttttagacga aagtgaattt 116880 ttataggttg aaatgggggt gaaggtttag tgcgtttttt ttttttggga gtttttttag 116940 ggtttgtgtt tattttgtga ttttgtgatt tagttttttt tttgagatga agttttgttt 117000 tgtcgtttag gttggagtat tgtggtacga tttgggttta ttgtaatttt tgtttttcga 117060 atttaagtga tttttttgtt ttagtttttt aagtagttgg gattataggc gtttattttt 117120 atgtttagtt aattttttgt gtttttagta gagatagggt tttattatgt tggttaggtt 117180 ggtttcgaat ttttgatttt aggtgattcg tttgttttgg gtttgttttg gttttttaaa 117240 gtgttgggat tataggtatg agttattacg tttggtattt agtaggtttt ggttgttttt 117300 tttttttgag atagagtttt attttgttat ttaggttgga gtgtagtggt gtgattatgg 117360 tttattgtag ttttgatttt ttggttttaa gtgatttttt tattttagtt tttcgagtag 117420 ttgggattat aggtatatgt tattattttt ggttaatttt tgtattgttt agtggagtcg 117480 gggttttgtt atgttgttta ggtttgtttt gaatttttgg gtttaagcga tttgtttatt 117540 ttggtttttt aaagtgttgg ggttataggc gtgagttatt acgtttggtt tagtaggttt 117600 tttagaagcg tttgaggttt ggtgaaggta tggtgttatg gagtagagaa tatttaattt 117660 tgttttcggg gagtcggaat atatttttcg tagttaattt taatagttat gacgtggtta 117720 ggatgatatg gggagggggt ggtgtggatt gtgtgggagg ttagtttttc gggaaggggg 117780 ttggagtggg tttggttttg aggaggattt ttaagaggag gaggaggcgg tggtatgttc 117840 gtttgggggg atggcgtgag ttagggtggg tattttttta tttaggtgtt atttttttga 117900 tattttagtc gggatatggt ttttttgggg aagatggata tttttagagt ggggtatttt 117960 ttggggaaga tggatatttt cggaatgggg cgttttttgt ttttattgtt tttttagtat 118020 atagttgtat ttttttgtag ttttggaggt tgtgagattt tttggttgtt atttagaata 118080 aattcgtttt tgagtagcgt cgttttgatg gtggggtggt ttttgcgggt ggaatagttt 118140 ttgttgtttt agagtttatt gagagttagt gggtatggga gtggtgttgg atcgaaatat 118200 ttagagggat tatagagtta ggtagtaagt atagaggtta gttagtgggg agggagggat 118260 ttatttatga aaagatatta agtattgaaa gagaggagag gatggttggg gatcggtata 118320 tatgtgtatt ttgcgtagat ggttaaggtg gtgaggcgtt agttacgtag ataattggag 118380 gaaggaggag tgttttaggg gaggggttag tttcggtttt agaatgattc gtttgtgtac 118440 gtgggtttgg ttggaataaa ttattgtatt cgtatcgtag atttaatcgt aagtttatat 118500 tagggtagtt tttgttttgg tgtagtgttt tcgattatga gttggttatg gtgggggtga 118560 ttttaagggg atttttaagg agggggttta tcggattttt tagggaaggt tatttgtttt 118620 tttgggttgg atttgggata aggttttttt ttgtttagtt tttgtttttt aatttgatcg 118680 tacggaagga tgttgaggat atttggaagt cggtttttgt tttatagtat ttataggata 118740 gaggtatatt atgtggggat agtttggata gtgtttagga ggtagggagt agattagagg 118800 atcgcgggag gttttgggaa tcgtacgagg atttaggtat tgagttttgt attttttggt 118860 attagttcga tgtatagttt ggttttgtgt ttatttcgta ttttattttt tttatttgta 118920 cgggggcggt aataatattt tttatagttt aggtttaagc gggtgtagat gtgatgagtt 118980 tggtaagttt attttattat atttagtttt gggtattgaa ttttggattt tttggttggt 119040 agaagtggat atttaatttt tttttggggt tttggggttt ttgtagaatt agaatatagt 119100 tagtagtttg tatgtagggt gtagagggat agagggatat tatgtcggga gtttatattt 119160 ggtatatttt tgattttggg gtttagtgtt ttgttgtttt gcggttacgt gattagttag 119220 aggttatggt tggatttata ggcgaatata gtttgtggat ttgattttgt ttggttttgc 119280 ggtgttttat tttattttta gttttagttt gtggagatag agtttcgttt tgttagttag 119340 gttgagtgta gtgatacgat tttagttttg taatttttgt ttttcgggtt taagcgattt 119400 ttttgtttta gttttttgag tagttgggat tataggcgag tgttattatg tttagttaat 119460 tttttatttt tagtaaagat ggggttttat tatattagtt aggttgttta gtgttttaaa 119520 aagggtttgt tttgttttgt gttagtattt aaagattagg agatattata taaagattta 119580 gatttttatt tttttgagaa gtgaatagtt ttggttacgt cgggtttata ttttttaggg 119640 tagtgacgga gttgagatag ggtttgtgat aattgagagt tttttggagt ttatacggtt 119700 ttttgtttag tttttggtgg aggttgagtt tagtgattta ggatttcgtt tgtgtttatt 119760 aagaaggaga ggtgtttgtg gtttagagag ggcgtttata ggagtgtttt gtttaggaag 119820 ttggtagttg aggcggttag ggttaggggg ttgggttttt tttttttttt tttagtgttt 119880 gagtgtattt ggaggaagag agacgggtga ggggaaggta ttgaaattgg ttttggagcg 119940 ttattattgg gggttgggga ttagttgtta tttttttttt tgtgggtagg ggaggtagtg 120000 gtgggatttt atgagattcg gattttgtgg tttggtgagg tagggagcgg ttggggagat 120060 attgtgggtt tttatagggg tgcgttgtgg gtttggtttg gggaaggagt tggtgaatgt 120120 gtttgttatg tgggtttttt tttgttttgg ttttgataat taggagcggt tggtttttat 120180 ttggagtgcg gttgtgggga ttgtggaggt ggtagttttt taggtattat ttttattgtt 120240 ttcgagggag tagattttgg tggagaggta ggatggttgt agggcgggag ttggtggttg 120300 gtattattgt acgggtttgt agtagtggat gggaagatgt aggagaggtt gatgattgag 120360 aaagttggtt tttgtggatt aagttggggg agtcggataa ttaagtggtt agaattttgg 120420 gttttggtat tagtttgatg tatagtttgg ttttgtgttt atttcgtgtt ttattttttt 120480 tatttgtatt gggggtattg gtatttttta tattttaggg ttaagcggtt gtagatgtga 120540 tgagttcggt aggttcggcg tttcgtcggt attgaaagtt ttagtgttcg tttttagtgt 120600 tattgatggg gttttgtttt tgttgcggtt ttgattggtt atagttgcgg ttatttatta 120660 ttggaggtat gtttttcgtt gtggttgatg gtagaggtgt gtttgttggt ggtgttttag 120720 tgtgtgtttt ggttggaggt gaggagggat aaaaatagtc gcgataagaa ggaaattaag 120780 gtcgggtacg gtggcgtacg tttgtaattt tagtattttg ggaggtcgag gcgggtggat 120840 cgtttgaggt taggagttcg agattagatt gattaatatg gtgaaatttt atttttatta 120900 aaaatataaa aattagttag gtatggtggt tcgtgtttat aattttagtt attggggagg 120960 ttgaggtagg agaatcgttt gaattcggga ggtgtcgttg tattttagtt agggtaatag 121020 agtaagattt tattttaaaa aaaaaaagaa ggaaataaaa gttttttttg gaattagaac 121080 gtttttatgt agacgtagtt ggagggggag gttgtgtggt ttgcgtcgtg gttatggtaa 121140 gatacgacgg gtagtatttt tttattttag tttgtatttt tgttttagaa tttatgatgg 121200 tttttttagg atggggttgt ttttttcgtt tgttgagata tgaaggacgg gaagagattt 121260 tcggttttta tcgtcgtatc gtttgttttt ttttgttgtt ttttagtagg aaatatgtcg 121320 gagtgttttt tagttattta tttattaatt gtattttttt tttttatttt ttagttttga 121380 aaagattttt tgaggtcgag gaggtcgaga tatttaattt tattttattt cggagggttt 121440 agattttttt atttcgagtt attgtggtta gttttattta gaaattttag gatttgggcg 121500 tgaagaattt agaattttcg gttcgttatg tggatttttt aagttaacgt ttttttaagg 121560 cgtttttgcg gagggtggag ttttcgggtt ttaaggcggt cgagtcggtg tttcggcgta 121620 ttgagttgtt tattgatatt tcgtttaagt aggtggagaa cgtcggggtt atcggttcgt 121680 ttcggttcgg gtttaagagg gtcgaggtgt tgggttataa gacgttagaa tcggtttttc 121740 ggaggacgga gattattatc gttaaatttt aggagttagt ttatcggagg atggagtttt 121800 ttgtttttaa ggttttcgag gtgtttattg tttttgttat cgacgtagtt tttaagaggg 121860 tggagattta gatgtttaag tttgttgagg cgtttatcgt ttttagttta gtttagattt 121920 tggagaattt agagtttgtt tttgtgtttt agttgtagag taggttggag tttaagtttt 121980 agttttttgt ggttgaggtt atatttcgga gttaggaggg tgagtcgtag agcgttaggt 122040 tttggatgtt gtggtaatgg ggggtttggt tgttggtttt gttatagaat tttggaggaa 122100 gaagttggat atggggtgga gggtgttatt ttggagattt agaaagatcg gaatgtatgg 122160 gggtgggggt ttgtaagttt aggagaggtg gttttttttg tttgatggga atatgttaag 122220 atgttttaag cgggatttga atgagagttt ggaaagattt tttgggtttt aaggagtttt 122280 ttttatgggt tatcgtgggt tttgttggga tttttgtttg ttgtgtgttt ttggagggtt 122340 tgggaggttt agagaatgag gagttacgta ggaattaggg taggtttatg taggggtgta 122400 ggatagggtg gagttgagat ttttagaagg gttgttatat tttggtggtt tttgtttgag 122460 gaattgtagg ttgtttggat atgtttagta gaggtcgagg gtttggggaa gggaggaggg 122520 acgtatgttt tttgaggttt gtattggagt ttatggtttg gttttttttt tttaggaggg 122580 atggttgtgg tagagggagg ggaatatgag gagtatttta gtttgtagga taaaattttt 122640 agggtattgg gaaggggtgt ttggattagg gggttgtgtg atagttgtat acggttttat 122700 ttgggggtgt ttttttggcg agaggagaga ggttatgggg ttttagtagc gttttgggag 122760 ggtttaagtt tatagtcgtg ttgatatgga gtttataggt aggggattgg tgttagtttt 122820 gtgggatata gggtttgttt ggaaatgtta ggttgtggga tatggttggg ttttttttta 122880 gaagcgtgtt ttttggtttt agtagggatc gtggttttat ggggttatag taaggtgtta 122940 gttgggttag aagtttttta agagttaggt ttgattttgg gtataggatt agaatttagt 123000 aatgtttagt aagttttttt taggttggat aaatagtata gtttgggttt ttgatttagt 123060 tgttgttttt tatttttaat cgtggtgaaa tatataatat ataatgtgta attttagtta 123120 ttttgtagtg tacgttttag cggtatttag tatatttacg gtgttgcgta gttgttatcg 123180 ttgtttattt tcggtatttt ttttattttt ttaaattgag tttcgttttc gttagattaa 123240 gttttttatg tttttttttt agttgttggt agttattatt ttattttttg tttttattat 123300 gaatttattt gattatttta ggaattttgt gtgtgtggaa aaatataata attgtttatt 123360 ttgtgtttgg tttattttat ttagtatgac gttttaaagg tttattcgtc gtgttgtagt 123420 atggggtaga attttttttt ttttagaggt tgaataatat tttgttgtgc gatgtatttg 123480 tgttgtgtag ttgttttttt atcggtggat ttttgggttg tttttatatt tttttaagtt 123540 ttttttttta ttttttttga tttttttttg atttttttga gatagggttt tgttttgttt 123600 tttaggttgg cgtgtagtgg tgtgattatt gtttattgta atttttgttt tttgggttta 123660 agtgattttt tagttttagt tttttaagta tttaggatta taggttgcgc gttattatgt 123720 ttggttaatt tttaaatttt ttttgtagag ataggttttt attaggttgt ttaggttggt 123780 tttaaatttt tgggtttaaa tgagtttttt gtttcggttt tttaaagtgt tgggattata 123840 ggtatgagtt atttaatttt tttttggttt ttttttttga atgagagttt tttagtggtt 123900 agtgggtttg ggggttggga ggatgtgggg tttggagagg gtgtgggttt ggggggagat 123960 tagtgttttt tatgttttta tgggtatgtg gagtgtatat ttgttttggc gggtttgggg 124020 tttgggattt tgtatttttt atagaggggg tatcggaata tattgagtag ttagaggtta 124080 gtgggttttg gaaggttttt ttcggttttt agtgtgcgag tttcgtgttt ttttttttat 124140 ttttttaagt ttgattttga agagttattt tgttttagtt atttagattt agtgatagtg 124200 gttgttggtg gtatggtgtt aggttaaagg tatgggtagt ttgtagagtg gtaggaggtt 124260 gttttttttt ttgttttttg ttggtgtagg atttttgttt gacgtgtcgg atatattttt 124320 attttgggtt gatgtgttta tatttagttg agttaaatag gatgtggttg gggaggcggt 124380 tgttatcgag ttatttaaat ttcggtgatg gttggtgttg gatgtatagg gacgtggttt 124440 tggttttggg ggataggtag ggggatgttt atggggatgt ataagaatat ttttttttag 124500 gggtagatat agtttagttt ttaaattgtg ttagagattg tgtcgggagt taggtttagg 124560 gatataattt gcgggttttg ttttttggag tttatcgagt cgtgagtagg atggttggga 124620 tataaggagt gtttagggag tttttttagt agtggaagta taattttatt aggttaggaa 124680 ggggagagaa aggtaggtta cgtggaggta gtagcgttta gagttgttag gaatttggcg 124740 ttttgggggg acggtggttt tttttatgga ataggatgta tacgttggag tcggggtatg 124800 ggagaaaatt attagtattt tagattcggt tatttacgga tagggatttg tgtaggtggg 124860 agtttagttt acgtggagag gttcgtgggt tgggttgata gttttgaggg tttaagtaag 124920 tttaggtgga ggaaatgtag ggatagacga gggtagggtt tttttaatgg aggagtgttt 124980 ttgaaattcg atgggagtgg tttttcgggg ggtttaggtt tgagttttat tagttttttt 125040 ttcgaggtat tatttgtttg ttttttcgtt tttttttttt gtgttacgat cgttttggat 125100 acggatttag ttttttttaa tttagttttt tgtttatttt ttttttaggt ttattttttt 125160 ttgttttttt atgtggggtt gggttgggag ttttttgagt ttcgatatgt atagttttga 125220 ttaatttttg cggttttttt gtttttcgag tattagggat ttagttggta ttatggggaa 125280 aggaattatg gagggagttt cgtgtttttt gagtagacgt ttagtttttt ggtttttgtt 125340 tgcgggaggg tatttgtgtt gtggtttgtt tttattttag agttgtgggt gtagggtagg 125400 gttttttggg gttttagttg aattgttttt agattgattt ttttaaagta tagtattgtt 125460 gagatttttt ttcgtgttga gttttttttg tttatttatt ataggttttt ttacggttga 125520 tttatttttt tgtttagttt atattttttt tttttttagt tttttttgtt ttggtttttt 125580 tttggttttt tatatttttt tttataattt ttttgttttg attttttgaa ttttgatttt 125640 tgtttttttt tatattattg ttttggtgaa tttttatgta ttttttaaaa tttggtttaa 125700 atatttcgtg tttggtttgg gatataaatg atttgtgtat aaattttttt ttttttgtta 125760 gatttttttt tttaaatgtg aaagtagttt tttagattat aaaaagtaat cgagtatttt 125820 ttttttaaaa tgtaggaagt atagaaatga gaaagaattt aaaatttatt tgtaagttag 125880 cgatatttat gtttgaggtt ttgttgtata gtttttaaaa ttttttttat gtttttatta 125940 gattttgagg gtagggttgt tgtttttgtt tttttttgtg tttttttttt gttttttgtt 126000 ttttgagatg gagttttttt ttattattta ggttggagtg tagtggtatg attttagttt 126060 attgtaattt ttgtttttta ggtttaagcg atttttttgt tttagttttt cgagtagttg 126120 ggattatagg cgtgggttat tacgtttggt taatttttgt atttttagta gagacggggt 126180 tttattatat aggttaggtt ggtttcgaat ttttgatttc gtgatttatt tattttagtt 126240 tttttgattt tttaaagtgt tgggattatg ttatcgtgtt tagtttgttt tggtttttat 126300 aaagaatttt ataaggggtt aggtgtagtg gtttatgttt gtaaatttag tattttggag 126360 gtcgaagtag gtagattgtt tgagtttagg agtttgggat tagtttgggt aatatagaga 126420 aattttattt ttataaaaaa tataaaaaat tagttaggta tgatagtatg cgtttgtagt 126480 tttagttatt ggggaggttg aggtgggagg attatttaag tatgggaggt tgaggttgcg 126540 gtgagttgag attgtgttat tgtattttag tttaggagat agagtgagat tttgttttaa 126600 aaaaaaaaaa aaaaaaaaaa aaaattttat aagatattaa gtaagtgatt tggatataat 126660 aggtgtgtta tgaaattatg ttgaaggagt gagttattgg tggtgagttg ggatggtttt 126720 tttgtggttt ttgtaggtag atgtagtgat ttttatgggt cgtttttaga gattaagtag 126780 aaattttttt ggttaatttt atttttagga tatttggttt tttttttgga ggttgtgttg 126840 gagggtttag tgggtgggtg ttggttttag tgtgggggtt ttggaaggag ttagtatttt 126900 aggagggagt gtgggtattt agatggttga aggggaggga gaggaagaga ggcgttgtag 126960 agggtagagg tatttttgtt tgttttttcg ttttagggtt tggtgaggtt tgagttttat 127020 gttggtgggg tggattttcg gttttcgagg ttttggtttt gtttttggat ttggtatttt 127080 ttttgttgtt tttttataga agggcgttta ttttttgggg ttatttttgg tttttttagg 127140 ttttgggtgg ggacggtttt gttttttttt ttggattttt gttttttttt tgttttttaa 127200 tatgggtgtt tttgggtgga gtggggtggg gttgggttgt agtatttagt attgagtttg 127260 taagggttgg ttgttggttt agagtttttt ttattagagt tatttttttt cggtttttta 127320 gttatattag ttaagttttt ttagagttgt tttataaggc gggtgtttag cgttcgttta 127380 tgggtttggt tttttgtttt tttgggatgt ttattggggg taagagggag gttaggttta 127440 gtgtttagtt tagttttggg tatgttttag ttttgtttta tgagttaatt ggttttgaat 127500 tattatttta ttttttttag ttttaatttt ttgatttgtt aaagaggtat ttgtagaggt 127560 ggttgggggt tgagttttta tgtatttatt tattttaaga attaagaagg gagtttatag 127620 tggttttggg gttatttgtg aatatggatg tgaaattggg gcggggtaga tatggtagta 127680 tgttttagta gtttttttgt gatttagagg gtttggaaat ttttgttatg tgggtggagc 127740 gttgagggag tagggggtta ggttttttcg agttgatgat ggtgggcgtg gtttttcgta 127800 tatttggttc gtatcgggtc gtgtgtttta ggggtagaat agggaggaat tttagtatag 127860 atagtagggt tgttagtata gcgttgagta tagggttaat taaagtatag ggttttttgg 127920 aattatttaa tatagagtag tgaagaggtg gttttgggga aagtggggtt agagttgagt 127980 ttgagtgggg ggtggggagg gcgggtatta gtttgtaagg gagggatatt tattgggttt 128040 tagaagtttt tggtggggat tagggattgt gaagttgggg agagggtgat tattgtgatt 128100 tagggaggaa gggttttata gatagtttag tttttggttt cgtgtttata ggatatttta 128160 tataggtttt gagtttattt ttggattgtg gattttttga ggtagggtgt gtaggttcgt 128220 ttagtattag gtgtaaggta gggggttttg gtaagcgtcg agggatttat tggtgtttga 128280 tgaagtagtg agtttggatc gtgttatgtt tcgggttttg agtttgtagg atttttttgt 128340 ggggttgtgt gtttttgttt ttggaggtgt ttagaaggta ttgacgtttt tgtcgggatg 128400 ttttattcgg aaggtttcgt tgtttttatt tttttttatt tttttgagtt gtttgtagag 128460 ggtatttagg ttttttttta ttttgggatt gggttttttt tttttttttt ttttaagaat 128520 aagtattttt ttttttcgaa ttgtttttgg agttttttag atttaggttt agagtgggaa 128580 gtttcgtatg tgttggggga ataggaatta atgcgggagg attggttagg ttcggtgtgt 128640 ttttttcgtg gtgggacggg gtggggttag agaatagagt ttggttttag agtttaggaa 128700 gagaattttt tttttcgtcg gtttgttaag tatcgtgtag tggtgagagg aaaggagggt 128760 tggttcggga atgtagcggg tgtcgagtag ttgtggaata ttttaaatag agcgtagttg 128820 cggggaaggg tggggttagg aggtaggcgt tgggggcggt ttttttgttt cgttttttgt 128880 agttttgtgg ttttgattat ttagtttggt tttaggatgg agtttcggtt tttagatata 128940 tggtattggg tgaggtcgtt ttttagtatt tgttttagga agttagagta gttgttagaa 129000 gagagaggag ttgtgtttgt attcgtcgtt ttttaggttc gggatagttg tcgggattga 129060 gggtttgtat aatggcgagt ttgttcggag gggcgcgtcg cggttagata gttatgtttt 129120 gtgcggtgtg gatagagggt atatttagtt ttggaggagc gtatttagat ttttcgtttc 129180 ggggtttaaa gtgtgggtag tttttaatta gattttggat tttagtagat agtttgggag 129240 gatgttatgt ggtttatttt gatatattgt tttatttgtg attttatttt tgagagttgt 129300 agggaggcgt ttttttagtt ggattttatt tttttttcgg ggttttttgt gggtgttata 129360 agtgattttg ttttttttag tttaaggggg gtttttgggg tatgggttgt aattgatagg 129420 ttagagtagt ttatggttag ggttgagttt ttttttcgtt ttttttgaat attgggttta 129480 ggaaggggtt aaagtggaga tgttttgatt aaagttgagg gaggtatgga gtttttttga 129540 ttttgttttt ttattttatt gttgttattg ggtgtatttt gtggagtttt aggattttta 129600 aagaatttag agtggagatt ttcggtttta tttagtgtag gtgaggggga aagtgatttg 129660 tttatagtta tatggttatt attagtatat ttgggttaag ttcgatttta ttttacggtt 129720 tttgtttgaa atttggaatt ggaaatggtt ttggaaatta ttgattttat ttgtcgtttt 129780 ttaaaatggt tcgtagaggt taagatatag atttttgtaa tgttttgttt attcgtgtgt 129840 ggggaaatgg tagaggagta tcggttttgt ttttatattg tttgggttgt cgtttttgtt 129900 ttgtttagtg gttttttttt ttggttcgtt tttttattgt ggaagtgggt ataatttttt 129960 ttgtgtagcg tggttagagt ggatagtgat gattcgtgaa gtagggtgga gcgtttgggg 130020 gattcgtgtt aaataagtat ataaataaaa gttaatataa tttttattta attagtaagt 130080 aggttttgtt tgaagttttt gggtagtatt ttatgttatt tttaggtttt aggtcggtgg 130140 tgtcgtttcg tgtttttttt attcgtaagt tggtgtttag aagttttgtt ttgtgttttg 130200 gtttttattt tttttgtgat tttttttttt ttttatttta aaaagtaatg tacgacgggg 130260 cgtggtggcg ggtatttgta gttttagttg tttgggaggt tgaggtagga gaattatttg 130320 aatttaggag gcggaggttg tagtgagttg agattgtgtt agtgtagttt agtttgggta 130380 atagaataag atttttattt gggaaaaaaa aaaaaaagcg atgtttagtt atttttagat 130440 agaaaatgaa gattatatga aatttggaaa gaagtttttt ttttttattt tttaattttt 130500 ttttaagggg tggttatgtt gatagttggg tgtggtattt ttttgaattt tatttttgta 130560 gagttattta gggtttgtgt aaaaaaagtt aatgtgtaaa tatagatttt ttaagaatat 130620 aaaggaaatt agatttttgt tattagtttt tatttttttt atttaataat attgttgtta 130680 tttgtagatg tagtacgttt tttttttttt tttttttttt ttttttttga tagagcgtgg 130740 tttaggttgg agtgtagtgg tgcgatttta gtttattgtg gtttattgta atttttattt 130800 ttcgtttttc gtttttaagc gatttttttg ttttagtttt ttaagtagtt gaaattatag 130860 gtgtttgtta ttatatttgg ttaatttttg tatttttagt agagacgggg ttttattatg 130920 ttggttaggt tgtttttgaa tttttgattt tgagattcgt ttatttcggt tttttaaagt 130980 agtacgtttt ttttaatggt tgtgttatta gttgttttat ggttttgtta ggtttgttta 131040 gttttttatt gtgattgaga ggttgtaata gatgttttcg tatttgtata tgtgtatata 131100 tgattgaagg atgagttttt agtgaatttt tgtgttaagg atgtgtgtat ttaagttttg 131160 atttgttggg tatagtggtt tatatttgta attttagtat tttgggaggt taaggcgggt 131220 tgattatttg aggttaggag tttaagatta gtttggttaa tatggtgaaa ttttattttt 131280 attaaaaata taaaaattag ttgggtatgg tggtttgtgt ttgtagtttt agttatttag 131340 gaggttaagg taggagattt gtttgaattt agtaggtaga ggttgtagtg agttaagatc 131400 gtgttattgt attttagttt gggtgataga gcgagatttt ttattaaaaa aaaaaaaaaa 131460 aaaaaaaaat tgatttttgt ttttgaattg gtttttaaag tggttattag aattttttag 131520 gatttttttt ttcgtcgatt tgtttagttg tttgttgggt tttgtgtagt gatggtttag 131580 tagggaggtt ttatgttttt tatttttggt tgagggttaa atgtttttta attggtgttt 131640 tattttgtgt atttcggtta agcgagaggg attatttttt cgtatgttat aggttagggt 131700 tttgtgtttt ttttttattt ggaaggtgta tttttttttt gttgaaattt tttaaaaaga 131760 gttttttgta agttaggcgt gatggttaat atttataatt ttagtatttt gggaggttga 131820 agtgggcgga ttgtttgagt ttaggagttc gagattagtt taggtaatat ggtaaaatcg 131880 tatttttgta aaaattagtt gggtgaggtg gtgcgtttgt agtttcggtt attcgggagg 131940 ttgatgtggg aggattattt gagtttggga gtttgaggtt gttgtgagtt gtggttatat 132000 tattgtattt tagtttgggt gatagagtga gattttgttt aaaaaaaaaa aagagttatt 132060 tgtatatttt tattatagta ggtacgagta ttttgttttt agttgtttat ttttgatttt 132120 gtttttggga tgttttttta tatagaatat tttaattttg atattgttaa gtttttgttt 132180 ttttttttag tttttggaat ttatattttg tttagaggtt ttttgcgttt tgaaattata 132240 ggaaagaatt ttatttacgt ttttttttag tatttttgtg gttttatttt tatatgttga 132300 aattatgaat ttattggaat gtattttggt tttagtagcg aggtaggggt agatggtatt 132360 gtttggatat atagtagcga gtttggtttg gagcgggtgg ggcgtgtgtg tgtgtgtgtg 132420 tgtgtgtgtg tgtgtgtgtt atttttatta gttttggtgt ttgtattgtg ttggtttagt 132480 aaaaataatt tggatgtatt ttttttattt tttgtttttt ggaatatttt aagtagtaat 132540 ataataattt ttttgttaaa attttttaag aatttattcg tgaaattatt tgagtttgat 132600 atttttgggg gagtttagta ttttaaaaat ttaaattttt tttatgggtt tgtgagtttg 132660 ggagtttttt ttttttttta aaatttatta ttattttttt tttagaaaag tgttttttag 132720 tttatttaaa attcgttagt ttatttcgag ggggttgttt tagttcgttt agtgaggata 132780 gtgtgtagcg cggtgattga tatgattgat tagtagagta cgatcgatta gtcggtgtgt 132840 aaatatgatt gattgtggtt agcgttttgg gatgttttat gttgaggtat atgtgtgtag 132900 tgtagggtga tgtgtatttt gagaggggat gaagttatag gatttttgta tttttaggag 132960 agagtttttt tttttaaggt tgtagttttg agtaggtagt gacgggattg ggtttagggg 133020 gttgagtggt tttagtaggt taagggtttt aggaattatg agaagtttgg agttgtttag 133080 agagtagttt ttaaaattag tttggattgt agtttttaga aagatatgcg attgatatta 133140 cgaattagga tatatttata tatggggtgg gggtggggat gggatgtatt aatgaaatta 133200 aattttcgtg atggaatttt tatttttatt atgcgtgtgt tatatttagt attttttttt 133260 tttttttttt tttttttttt tttttttttt ttttttgttt gtttgttttg gagagaggga 133320 aggttttttt ttattttttt ttaaatagtt ttattgagat ttaagtaagt tattatataa 133380 tttattaatt tatttattta tttatttttt tgagacggag ttttattttt gtcgtttagg 133440 ttggagtgta gtggcgttat ttcggttgat tgtaattttc gttttttggg tttaattaat 133500 ttttttgttt tagtttttcg agtagttgag attatagata tgtattatta cgttcggtta 133560 attttgtatt tttagtagag acggggtttt tttatgttga ggttggtttc gaatttttga 133620 ttttaggtga tttattcgtt ttagtttttt aaagtgttgg gattataggt atgagttatc 133680 gcgtggttta atttatttat ttaaagtgta taattttatg gtttttagtt tatttagaga 133740 gtagtgtaat tatcgttatt ataattaatt ttagaaaatt gaaaatttga gaaatttaga 133800 aaattttttt tttaagaaga aatttcgtag tttttagtta ttaattttgt tttttttttt 133860 tatatttttt ttttatttgt gtggattttt tttttttttt tttttttttt tgagataggg 133920 ttttattttg ttatttaggt tggggtgtaa tggtttaatt tttgtttatt gtaattttta 133980 ttttttaggt ttaagttatt tttttattat ggtttttcga gtagttgaga ttataggttt 134040 gtgttattat gttcggttaa tttttgtatt ttttgtagag atggggtttt attatgttgt 134100 ttaggttggt tttgaatttt tgggtttaaa tgattttttt gttttggttt tttaaagttt 134160 tggaattata ggcgtgagtt attgcgtttg gtcgatttta gatatttttt gtatagagaa 134220 ttgtacgttt ggtttttgtg tttggttttt ttatttggtg ttatgttttt aaggtttatt 134280 tatattgtgg taggtgttag tgcgtttttg agtaatattt tattatggta tggattattt 134340 tattgtggat agatatgttg tttttattag ttgagggata ttgggttgtt gttatcgttg 134400 gtgagtgtat tttttttaaa ttaaaaaaaa aatgttggtt attatttatt agatcgtttt 134460 tttggtttat agggtgggat aagtcggttt gggtgagggt taggaggtgg ttaggtggag 134520 gcggttggag cggttttggg ttgtttttgg gcgtagtagg tagaggtgta atggtagagt 134580 ttgagtaggt tttttgggcg gatttttatg tcggtaatgt ttgtttattt aagaagtttc 134640 ggttaggcgt ggtgttttat atttgtaatt ttagtatttt gggaagttga ggtaggtaga 134700 ttatttgagg ttaggagttc gagattagtt tggttaatat ggtaaaattt cgtttttatt 134760 aaaaatataa aaattagttg ggtgtggtgg cgtgtatttg tagttttagt tattcggtag 134820 gttgaggtag gagaatttgt ttgattttag gaggtagagt ttgaatttag gaggtggagg 134880 ttgtagtgag ttaaaattgc gttattgtat tttagtttgg gtgatagagt gagattatgt 134940 tttaaaaaaa aaaaaaaaaa gaaaaaaaaa gaaattttta gtgttgtttt gtgttcggta 135000 tcgaagtcga gggaaggtag tattagtatg agtttttagt ttatcgggtt tttgtttgga 135060 gttgacgtgc gattaaggta tacgagggaa gtatggcgag gtggacggtg cggaggtata 135120 aggagtaaaa taaggtagat gtagtggttt agtggttttt ggtggttgcg aggagcgtgg 135180 gtaggatagt tttaggaggg tatttggaga gtagggtcgg ttggggtaag gtgtgttagg 135240 tatttgttag gagtaaaatg taaggggata ttaaagagtt taggaattaa tatagatagt 135300 atttaatgta gtatttttta atatcgaaat gatgtatagt aatttttatg atgaataaat 135360 gttggaattt taaattaaga taggtttagt tttgtacgtg tatagttttg ttagagtttg 135420 tttagcgtgg aatttgattt gtttaaaatg ttgttttaaa atattgtttg atttttggat 135480 tttttggtat tgttttaatt tttgtatttg gacgaaggtt ttattttaat tttagttgga 135540 gagggttaag ggttggtgaa tttggttttg gatttgtaga gtttgtggta tttgagaggt 135600 ggggttagga ataggaagga gttggtgaga acggtattcg gtatgggatg gggttagatt 135660 agagtagtat tgtggttttt tttaattcgt ggttttgttg ttggatgttt ggcgttggtg 135720 ttgagttttc ggttttttga acggagtgtg atgaataacg gggtcgggga gtttttgggt 135780 ttttttttga agtagtagtg aagttaggga tatgtcggta gtaggtaggg agagggacgt 135840 ttggtttgtg tttggagtta gttgttttat ggaggagttg ggtgaggatg cggtgggagg 135900 aagatttttt tagttttgta tttttcgaag tataattgag tgtttgtgtg gtttgggggt 135960 tattttggtt cgaggatagt tttgttttgt ttagttaggt tttgaagagt tatcgggata 136020 cggatagtag ttttgttggg tggtaggttg tttattttcg tttatttaac gttggaattg 136080 gatgtagagt atttggatgg ttagttttag agtgtttttg atatttttag ttattttatt 136140 ttttagatta ggataagatg cgggatttta atttcgagtt ttttatgggt tttattttat 136200 gtgtttttat aagttattgg gtttattttt tggttttagg gttgtttggt tatttggtat 136260 tttggttttt ttatttgtat aatgaaaata atagttttag ttttttcgag gagttataag 136320 atgtttttcg tgtgaaaaat tgggatttgg tattagatta tttggatttg aattttggtt 136380 ttattttttt taatttgtgg ttttgggtta atttggtttt tttgttttta gtttttttat 136440 ttatagagtt attttattga gttgttggga ggatgaatat aaggaagtgt atttatgtgt 136500 ttagagtatt gtgattttat ttattattat taaacgaggt atataataag tgtttaatag 136560 atgtttagtg ttattttacg gattttgtgt gttttgtgtg tttttagtag ttaagttttg 136620 gaggtgggga agttgttgac gagttgtacg aggtaattag aaagaggagg ttataggtgt 136680 aagggtttgg gtgatatttg tggatagaga gaggtcgatg gattttggta gaggggaagg 136740 gggtttttgt atatagaaaa tgttttttgt atttaagatt tttgtgattt tggaatagag 136800 gtagtagagg tttgtaaatt ttaaattata aatttagaaa gtatagaata ttcgtagaga 136860 ggattagaaa tattatatat tttagtgtgt atagaatttt ttatatagtt aaataaaagt 136920 acgtttttaa ttgaagttgt tggagagttt ttgaggattt tatattagat aagggtcggt 136980 aagtggaagt ttaatacgta ggagttattt tttttgttta taaatgtttg tcgttttttt 137040 tgtttatatt cgtatttatg tgagggtatt tataggttta tcgtttagtt ttatgttttg 137100 tttgttatta aaaaattttt taagaatttt ttagttgtaa atttttttat cggagggggg 137160 gttttaggaa tttagttttg ttcggggttg gggtatttta gtatttgttg tataggcgtt 137220 ggttattaaa ggttatgtgt cgtattcgtg ggttttcggg gtttggtggt atttgggtat 137280 atagtttagt ggcggttttt tatttgttag atattgggag tggggggttt tttatttttg 137340 ttttttggcg gtggggggag tgtttcgagt tgttatatat tagaatttat cgatttatac 137400 gttgcggtat tttatagttt tttgatagtt ttttagtttg agagattatt aaattgagtt 137460 tttggagagg gtggttgttg aggtttggat ataggtgtgg ataggatagt tttgttttat 137520 ttcggagttt cgtttcggtt tagttttttg tgggtttgaa gtttaggttg ggttagtttt 137580 tgttttttag atggtcggaa aggtagttta gttttacggt ttttttgtta ggttttgaga 137640 gtcgtttggt ttttagtttt gttttttttt ttttttaaga tggagtttta ttttgttgtt 137700 taggttggag tgtagtggtg ttattttggt ttattgtaat ttttattttt tgggtttaag 137760 taattttttt gttttagttt tttgagtagt tgggattata ggcgcgtgtt attatggtag 137820 gttagttttt gtatttttag tagggatcgg tttttattat gttggttagg ttggttttga 137880 atttttgatt ttaagtgatt tgtttatttc ggttttttaa agtgttggga ttataggtgt 137940 gagtcgttac gtttagtttt tagttttgtt ttgatttttt tttaaggtcg tgaggatgtt 138000 tacgtttttt ttttttttta cggtttattg atgtttttag atgttttgta aagttatttt 138060 tttttcggga gttttttagt tggtgacggg ggattttttg gggattattg tttaggtagt 138120 tatgtaggtt tgtgggtcgt gtttttaggt tggatcgaga ttcggtgtat ggggtgtttt 138180 tggtttgagt tgaggttttt ggaagttata gttaggaggt agtaagggac ggttgttatg 138240 tttttttttt tttgtttttt agggtttttg cgggatagat ttttttgttt gagttttttg 138300 gttgtttata ttttggtttt ttaaagttta gtttgaagtt ttaggtattt tataatttgt 138360 tttttttagt agtttgtttt gttttttttt tgtcgatgtt tttgaaattt ttttgttttt 138420 ttttattttt tggttagaga gagattggag attttgtggg aattttcgag gggagggaga 138480 aggtcgttgt ttgaacggag gtggtttttt tttttgtttt tttttaggcg ggttatattt 138540 gtaggtttag ttttttgttg tggtagcgtt tggggtgtcg gttgtttttt gggtacgagt 138600 tgggagttga gggaggcgtt tttaggatcg gagtggtaat ttagttggag gaggagtaat 138660 aggttcgtgg ttagtagtag tcgtcgtagg gatttcggcg ttgtatttgt gttttagttg 138720 atttttttcg tttttttagg gtgggtcggg gatggtggtt tgttgtttag tttaggaaga 138780 agaggggtcg taattagtag tagttatttt aggggatttt agcgttgtat ttgcgattta 138840 gttgattttt tttttttttt tagggttggt tgggaatggt ggtttgttgt ttagtttagg 138900 aggaagaggg gttgtggttt ttattttaga ggtttttttt tcggtttttt tttcggtgtt 138960 ggtttaattg taggtttgtt ttaggtcgtg tcggtatttg ttgattgacg tttagcggat 139020 gttgatagga gagggttggg atggggaagt agtaagtttc ggttattgtg ggttcgggtt 139080 atagatggtt gaggtatttt ttggttattt ttaggaagta aggttttacg tagttttcga 139140 tttatttatt gttcgtgtgt attttaggag gttgtatttt ttaaggtttt tattaggtaa 139200 ttttattggg ttgggtgtcg ttgtaaaatt atttattggg tgcggtggtt ttttggtggg 139260 gggtatggtt ggggaggatg cggtggagga gaagttagtt tcgtggttgg ggggagggcg 139320 gattattcgt tttttgtttg ttttttgaat tggagtttat ggtttttttt ttaggtgttt 139380 gggttatgga agaggttata gttttgtttt atttttgtgg tagtttaggg gagttttggt 139440 tagtttcgtg ttttttggga gggcgatagt ttggttaggt tgtagggtag gattggaatg 139500 tagatttttg tttggttatg ttgttgtttg gttgttttgt ttggggattt tttgtttagg 139560 aagagagaag cgggtcggat agttcggttt agtgattgga agtttagttt tttatgttta 139620 gtttagtagg aagtttgttt tttcggaata tttgcgtgtt tttgtatgtg tttttttggt 139680 tggtggtttt gcgaggtttt tattgggttg cgttatgttt tttggttatt ttggttttgg 139740 tgtttggttt ttgtgaaata gagatatttg ggtagttttt tatttgtgtt tgtaagtttg 139800 tgtggtttta gtgatggttg attttgtttt atttagagga tttgggaatt tttagtttaa 139860 ttgtttagag gagttttttt tagtggggag agtttgagtt gtttttttgg tggatagttt 139920 tttagatttt aggcggattt ttttgtcggt cgtttttttt gttgtttttg tttttttgtt 139980 ttttatttgt tttttatttt tttttttgta gtagttagtt ggtacgggga tttttttttt 140040 tttttgggat tgtgaatgag acgatttttt tggttttttt gggtttagat ttttttggta 140100 atagttagtg aaatttttgt tttaggtggg aggagaaggt ttagtatgtg gttataataa 140160 cggttttaat tatattattt ttaaacgttg gtttttattt attttttgtt ttgtttaata 140220 gttattttta ttattttatt ttttagatta ggaaattaag gcgtagagag ttttagttat 140280 ttgtttgagg tttttatagt taagtgtttg gatttgaatt ttggagtagt ttggttgttg 140340 agttgttttg gagacggggt attgtgtagt ggtcggggta ggggtggagt tttgtcgtcg 140400 ttgattttcg ggttatttgg agtgataata tagtttagtg tttgggtttt tgtttgagat 140460 tttggttgga tgttaggagt tcgagatttt ttagtttttt tttgtgtaag gcgttatggg 140520 gtgaaatgaa agaaaatttt agttagaagg tgtttttttt tttttttagt tttttagttg 140580 ttttggattt tgaaataaga tatcgttcgt ttgtggggtg agtaggaata gattggaatc 140640 gtattttttt ttttttagtt atagttgtta ggagtttatt tttttttgtt tttttttttt 140700 gtcgtttttt tttataagat tgggttggat gttgttggga aagttaatag gaagtttttt 140760 ggttgcggtg gaggtggggg tttgtgtttt tttggggatc gagatgaggg ttttaggttg 140820 gtttcggtaa gagtagggag gtttacgttt ttgtttgttg gttttgtttt ttgttttggg 140880 agaaggtatt tatatgtttt agaatgtatt ttttgcgtgt atagggatgg tttttgggtt 140940 atttatttga ggtttattga tttttttttt tggaattgga gtggtttttt tacggtggat 141000 tgggttgagt tttttgtttc ggtcgacgtt tttttttagg tatttttttt tatcgtgtta 141060 gggtgtaggt tgttagtgga tgggttttta ttttcgggga ttggtagttg ttacgtttat 141120 tttatagtcg agatattttg gtcgaaggtt ttgttaagtt ttatggagtg tagggatttt 141180 ttttgagacg gttttttttt gtcgtttagg ttggagttta atggtttaat gtttcgttta 141240 ttgtgatttc gattttttag gtttagtagt ttttttattt tagtttatta agtagttggg 141300 attataggtg tgtgttatta tgtttggtta attttttaat tttaattttt ttttgtagaa 141360 atggagtttt attatatttt ttaggttgaa ttttaatttt tgggtttaaa tgattttttt 141420 gttttggttt gttaaagtgt tgggatttta ggtatgagtt attgtgttta gttggggttt 141480 ttttttaatt ttttttggtt ttttttaggt gtaggattcg ggttttagtt ttatgtgttt 141540 ttgaatagtt ttgggttttg ttttgtattt tttgggcgcg tggttaggtt tttcgtgata 141600 ttagtaggag atttaggtga agaagtaggt agaacggaat gtttgtttat ttagtttcgg 141660 ggttaggcgg ggcggttagg atagtagtag tggttggtgt ggttttttgg gaggttagtt 141720 tattggcgtg gttagcgaat ggggagggga gttttttttt ttgttttttt ttatttttgg 141780 tttttgggtt tttagggtta ggtttttaga gttttaggtg gaggatggag gttagggaag 141840 ttggggtaag agcgggttgg gggtgggtgg ttaggcggat tttggaaaat tattttttgt 141900 aggtttcgtt ttttttaggg agtatttagg gttggtttcg gggagtcggg ttaatggtta 141960 tttcggatgg tgtaggggtt tatttttatg aaatcgggtt tatttttatg aaattgggtt 142020 tatagaagtt tttggtttcg gttttgtttt gttttttggt ttttgttttt aaagtaggat 142080 ttaggatagt tttgaatttt ttgtcgaaat gtagtttttt gggttttaat ttagtttttt 142140 agaattagag tttttggggt gggttttttg tttgtttagt agtttttagg ggatatttgt 142200 gtttgttaga gtaagtttaa taagtattgt tgtaaatttt tcgtttttat agttttttgg 142260 ttcgtttttt tttttttgtt gggatttgta ttaggattaa atgttaatat tagggattag 142320 gttatatttg tgaattttga gataatattt gtattttttt tttttttgag gttgttttgt 142380 tcgttttgtt atttaggttg aagtataatg gtgtgatatt tatttatggt aatttttatt 142440 tttagggttt aagtaatttt tttgttttag ttttttgagt agttgggatt ataggtttat 142500 attattatat ttggttaatt tttgtatttt tagtagagat ggagttttat tatgttggtt 142560 aggttggttt cgaatttttg gttttaagcg attcgttcgt tttagttttt taaagtgttg 142620 ggattatagg cgtgagttat tgcgttcggt ttgatattta tattttgatt aagttgttgt 142680 ggaaatattg agtttttttt gatagttttg tttatagagt gaatgtttag gaatcggcga 142740 ggtatttttt atttttattt agatggcggt ttggaggtag cgtttttgat tttgtgatgg 142800 gatttgtttt ttttgtttaa gagattttag agatgtggtt tttgaatgtg ggggtttttg 142860 ttggggtggg aacgggagtt ggttttggtt attgtttagt gattttattt tagtgtttcg 142920 attttagtat tttcgatttt agcgtttttt ttttttcggt ttcgcgcgga gattacgtgg 142980 tttgcgttga gtaatttttt attgttttcg tcgcgttttt gttgtaggga agttttttta 143040 gggagttagt tgatatattt ggtttttatt atttgttttt gaataggaat gaaaggagag 143100 agtgagtaag aaagtggtag gaggtggggg ttgtagagta ggggaaggtt agagagaggg 143160 gaggaaagat ttggaaagtt taggtatgtg ttttggaagt aggtgttagc gatgagttta 143220 tttggagggt ggtcgttcgt tttgagtttt gtttggggtt agtagggaat attttgttag 143280 ggtatgtcgt tgggagtttg tttttggttt attttttgtt gttttgagcg ttgagtagat 143340 ttgtttttat tttagggata acgtaaggag gttgttattt tattttttat tttattaata 143400 ttttatgaat tataagtgat tatttattgc gttttgacgt attttaggcg ttgggttcga 143460 agttttatgc gttttatggg atgtatttgt attatcgtcg tagaaaacgg tttttgttat 143520 tattgtagag aaggtatcga ggtatagaga ggttgaggaa ttggttttag gttatatagt 143580 tagaagcggt tgattttggt tgtgaatata gggttgtttg attttaaagt ttgagttggt 143640 ttgtagcgag gtttatggtt tttgtgttat tgtttgagtt tttggtcgag ttttttggtt 143700 tagtgggggg tttagtgatt tattagttgt tttattatat gttgtggata tttttacggt 143760 ttatttgggt gggagggaag gggttttagg aggtgggagg ggtataggga atatagttta 143820 gtttgtttgg gtttaatatt ttgattttta aggtattttt tgagggtagt atgaggttaa 143880 gtttttgttt ttttttagga ttttgttttt gtgagggttt cggggttttt tgtttttttt 143940 tgggggtttt gttggttagg attatagaga agttttttgt tgttgatttt tttgtttttg 144000 tattttttgg taagttattt tatgatttag ttgttttgtt tgtaaaatgg gttgaataat 144060 attgttttgt ttcggagggt ttttgggagg attaaatgag atttgttgta tagaagtttt 144120 ttgtaagtta tgttgattgg cggtcgtcgg gtttttaagt gaatgggtat tcgggtattg 144180 agtgtgtgga tttagtattc ggaaggaggg gttggggggt atttagaatt tttgggaggt 144240 ttggattttt gttttgttta gattttgagt ttttttttgg ttagtttaat ttttattagt 144300 agggtgaggg taattaggat ttacgtatag ttgggcgaag tcgagtgatt atatgtggaa 144360 gtttagcgtt ttttatgtaa agtgggtagg cggttaaagt gagttttgtt ttagtttttt 144420 tattttcggg gttgtttttg gcgttttgtt tttttttaga gttttattga tttgtattat 144480 gtgattcggg tttgggaaga tgggtttagt tgtgggaggt cgtgcgggtt ggggattgag 144540 agtgtcggag gagggttttt taggaaaatt tagttgtata ggaagtcggg ttagcggttt 144600 tcggaagttt ttgggttttg taagttggat tttttagatt tgtggttgtg gggttttttt 144660 ttgtttgtag ttgagagttt ttgattcgta tttgagggtt ttagaggttc gggaggggga 144720 tgtgatcgtg tttttagggt gaagtttatt cgagtgttat tttggatata gtttttattt 144780 ttttttggtt ttttttttgg ttatggggac gttgtttggg gggggttttt ttatatggaa 144840 ggagttgtag ttgagttggc gggtttcgta tatttttaag gtcgtttgat ttttagtttt 144900 taagtggggt tgtatttatt atttaggatt tggagtttta gttagagagg gattttttat 144960 tgtttttttt tttgtttttt gggaaaggta gggtttttgt gttttttttt atttagggat 145020 ttggtatgtt gggaggttaa gaggaagttg tttttcgttt atttattttt taattttttt 145080 agttagtaga gttttatttg tgtgtttaga atttgtgcgt ggagttagaa gttataaggt 145140 tggtttagtt gtgtttgatt ttggttgtgc ggttttggat agttttagtt tttttggagt 145200 tgagtatttt gatttgtaga ggagaggttg ttgtgtcggt ttcgtagggt tttgtgtaga 145260 ggggagtgtg tgcggttgtg agtttaggtt atgtttttag attggaggat aggatcggaa 145320 tagtgggtta ggatggttag agggttttag ttttaggagg aggtttttat attttttagt 145380 atttttatat taggaaatgt agttaggttt ttaggttttt tatgttagga agtagtattt 145440 cgttttttat ttttggttgt ttgggtttga gaagttgagt atttttttcg aattcgagtg 145500 ttttttgatt tttgtttggg tagttgtttt ttttgaattg atcgtttgtt ttatatagtt 145560 ttttgtggtt tgttcgatag ggtggttagc gagttttttg tatagtatat tttttttagg 145620 agtgttgttt gtgatgatgg tgtaaagggt gttttttcga gttttcggag gtatgtagtg 145680 gcgtaatagc gtgagtttag gagtttcggt gagtttttgg atggagaatt tgtttagatt 145740 attttttagt ttaaattttt tttgggtgtt tgttgtgttt ggggcgttga tttatcgtgg 145800 ggcggtttgt gagattttac gttatttggt tatttttttt agtttttgtt tattgtatcg 145860 gttttttggt ttggttgttt ttggaatatg agggtttatt tttacggaag aatatttatt 145920 tgtttttttt tggaaagttt ttttttagat tttttggtcg ttttatttag gttttgttga 145980 agcgttgtta ttttggagag gtttttttgt tattcgtagt taaaatagtt tttttatgtt 146040 tgtgggtggt tttttatggg gtatggatga gtattggaga gttttgtcgt ttatttgttt 146100 atatgttttt tgggagggta ggggatattg atttgtgttg tgggtgtttt gtatgttacg 146160 ggtgtttagt gaatgtttgt taagtattag gggagtataa aggagggaag tttttgttta 146220 attggagtag ttagggaaga ttttttggag gaagtggtat ttggtttgtt tagaatgtgg 146280 cgatttgttt gtatgtagat attagattag agggtaaagg ttattattat aatttagtag 146340 atagttataa gtagttaagg aattgttatg atatggattg ttcgtgattg gagttaagaa 146400 ggagttagag atagaggttt ttgtgttttg gcgtgagttt ttgggggagg ttgagttttt 146460 agaatgtggg gtcgtttgtg tagaggtcgg aggtgggaga tatatttgtg agtgtcggtg 146520 agtgtggggt gagttattgg ggttggatta gaagatggga atttttaaat ttattaatta 146580 gttttggtgt tttgggagtg ataggagacg gggtttttgg gggattaatt tagtataagt 146640 ggacgagatg ggatgtaggg gaaaggataa agttttttga ggttttggga agttgagtta 146700 gggtagagtt atgatagggt gagttttaga agtaatataa gaaaaaatag ttagattggg 146760 tttttttttt attgtgggag atgttttatt ttattttttt cgtttttcgg gttttggtaa 146820 tgggttgggt atagtgaatg ggttttattt gtaggagtgg ttatattttt tgggtatagt 146880 tgttttatat attgtattga gatgggattc gaggtcggga agaatagttt tttttgtagg 146940 ttgatattgt tagttttcgg ggagggaagg acggtagggg gtttggagta tttttttttg 147000 ttatttatat tttgtgtttg tttgtagggt tttgagtttt gtttgttttg ttttagtttt 147060 ggttaggaat ttgttggagt ttataggggt agttaggttg gaataggagg agattaggtc 147120 ggtaggggag tcgagagggg gttttggata gtatttaggg ttgagttatt ttgggtttgt 147180 tcgatttgtt atttggagtt gttttcgttt gtttattatg tgtaaggttt tgatttattc 147240 gggtttgttt aattagcgtt tttttttagg tttagttagt ttggttttcg ttcgatttat 147300 ttattgttat tagtgttatt tttgtattac gtaattagtt tttgtagtat gttagttatt 147360 aagtttaggg ttttttgtgt attttttgta atttttatag taattcggga ggtatagaga 147420 ggttgagtcg ttggtttata gttatatagt aggtatgggg tattgttagg atttagtcgg 147480 atttttgatt ttagggtttt tttagggttt tgggtgggat attggtaagg aagtaaggta 147540 tgaatattgg ttttgttttg gatagagttc ggggacggtg gtttggtagg tttagttgat 147600 atagtgattt tggtgtaggt ttaattattg gtaaagtgtt taagtatata tagaatttta 147660 attggggaga taggcgaagc ggttaaggga gggttgtgag tgataggtgg atattgtatt 147720 tattggtaga ttagttgatt ttggtgtttt ttggagtttt ttaatttttt tatttagaaa 147780 aagaggaatt aatagtttta tttttaaatt gggtgggagt attatattcg aaattgaagt 147840 aaagttggtc gtgttatagg ttcggtagat gttagttgtg taggtaattt agtgattatt 147900 tgaagtaggt tgtgcggcgg tatttttatt ttgtagatgt agtttagaga ggttagggta 147960 ttaattttgg gttatatagc gatagtttag gttatagaga gtagtgttgg atgggagggt 148020 gttggtagtt ttaggtatag gttgggaggg ttgtggggtt agtagaggga gggtatattt 148080 tttagttggt ggggtttttt tgtgttttag tatttatgtg ggtttaaagg agttggaagg 148140 agggaggtta gagttattta tgggtttaga agttgataag taggttattg attttgaatt 148200 tgttttatcg tatgtaaatt ggggataaat ttggggattt aatgatataa tgtaagaagt 148260 agatatgtta tagttttggt tatatagtta gtgtataata agtggtaagt cgttagagga 148320 ggtagtcggt gagaatggga gtattttagt agtttttcgt tttttgtttt tggttgtaga 148380 tgtatttgtt tttggttatt tgtgttttag tttcgtgttt ttcggtgtgt gtgaggttaa 148440 gtttttgggg tggggatttg ggggtgtgtt tgtagttttt gaggttaaga ttaaggttga 148500 ggtcgaggtt gaggttgagg ttattttggt gaggaggaaa ttgtaggtgg agaagttcgt 148560 tgatcgtgat tttgatttga tcgtaatttt gatggtgtcg atgtcgttag tacgtaggtt 148620 ttttgttttc gttacgattg gtttttgtag tttatttggt tgagaggtgt gttggttttc 148680 gtaggttgta aaatggggat attatcgttc gtttgggtta tagcgtgttc gtcgattgta 148740 tttggggagg gattgagggt tgattgtgtt gtggggatgt tggtagagaa ttagagaggg 148800 tatttaaaaa ggttaatagt tcggtgggga gaggaggcgt aaggttggtt tttgtttttt 148860 gggttttgat cgaaagggaa taggggatat atttggggat agtttttttt ttggaggaag 148920 aagggtttag ggtgttggtg tggagtttgt atagatgggg ataatgagtt ggagggtgtt 148980 gggtaggagt tggttagtaa taggttgacg agggaggttt tgttggttgg gtttggtttt 149040 taagtgagta ttttgagttg cggggattta gggggtttta gagattttag agttgagatt 149100 cgggattata gaggggtggg ttgtgtttag ggtaatatag cggatggggt agatgttgcg 149160 aaatttgttt ttttgttttt tttttttttg ttatagaatt ggattttttt agtttatggt 149220 tgttaaattt tttagatgtt tttgggtttt atgggcgttt tatattggtt tttttgtagg 149280 atagtagatt ttgggggttg gttttgatgg tatttattat ggggtatttt atgtaagtat 149340 agtgttttta cgtttagttt tttagtttgt ggagtaggtt tgtgtttggt tagttttatt 149400 ttgtggttag aggagggaga tagtggtttt ggagatagga gttggtttgg ggttgttttt 149460 ttagtttttg tttttttagt ttattttttt gttttgcggg tgttggttat ttttttttcg 149520 ttagttttat ttttagtttt ttttgttcga gtcgtgattt gttagtaggg ggtagtggag 149580 gttttgaaag tttttggaga ggattttgaa gtagttttta taaatttgtt tttggaaagt 149640 tttttttgtt atatttttag cggttttttt ttttttaata ttttttttgg ggttgttatg 149700 tagcgggggg tggaggaatt tattaggtcg tggatagagt agagttatgt tgatataaat 149760 tttggttgaa tttatatgtt ttttatagtt agcggtcgat tattggaatt agggaagtga 149820 ttttatagta agggttcgta gagtagttat tacgtatttt cgattttggt ttttggattt 149880 agttttggaa aagaagttag attttagtta tttggagttg tttagggaag attttagttt 149940 ggtgtcggtt gatagtttat tggaattttt tatttgtttg gttaggtgat gttaaggggt 150000 agaggttaga agtgttaaga agtaggtcga gggtggtggt ttacgtatgt aattttaata 150060 ttttgggagg ttaaggcggg tgaatttttt aaggttagga gtttaagatt aggttggtta 150120 atatggcgaa attttatttt tattgaaaat ataaaaatta gttaggtatg gtggtgtacg 150180 tttgtaattt tagttatttt ggaggttgag gtaggagaat tttttgaatt cgggaggtag 150240 aggttgtagt gagtcgagat tgtgttattg tattttagtt tgggtaatag agtaatattt 150300 cgtattaaaa aaaaaaaaaa gaagaagaat aagaagtgtt aagaagtatt tgtttttttg 150360 attgaaaagt aatttttgtt gggcgtggtg gtttacgttt gtaattttag ttttgggagg 150420 ttgcggtggg agagtcgttt gaggttaggc gttcgagatt agtttgggta atagaggtgt 150480 taggggtagt ggcgtttgtt tgtagtttta gttttttagg aggtttaggt aggaggattg 150540 tttgagttag gagtttgagg ttgtagtgag ttatgattat attattgtat tttagttttt 150600 gggtgatagg atgagatttt gttttaaaaa ataaaatata aataaaaaat taacgtttat 150660 tttttgtgat tttaaaaatt atatttattt gtgataaaat aattaaatta gaaaatgtaa 150720 aggaaatgat taataataat tgcgtttttt agataaatat tgttaatatg tttacgtttt 150780 tttttagttt ttttttatat agatatttaa tatttattaa tttgttttga attaaagatg 150840 gttttttttg ttttgtatga gaattatttt agttaggtac ggtggtttac gtttataatt 150900 ttagaaagtt gaggtaggta gattgtttga gtttacgagt ttgagattag tttgggtaat 150960 atggcgaaat tttattttta taaaaaaata taaaaattag tttggtgtgg tggtatatgt 151020 ttgtgttttt agttttttag gaggttgagg taggagaata gtttgagttc gggaggtaga 151080 ggttgtagtg agttaagatc gtgttattgt attttagttt aggtaacggg agtgaaatgt 151140 tgttttaaaa aaaaaaaaaa aaaaaaaaaa gttgttacgt tgttattttt tttagggatt 151200 tttatttttt ttatttttcg tttaagattt gttttgtaaa aggatgaggt taaatagtta 151260 tgggagggtg gtattggatg tttaaaaaaa tgtttcgtgg ttggcgggat ttagaaatag 151320 gttggggagg ttttagtaga gggtggattt tagttggggg tggggggtag taggggggtt 151380 ttttatatgt tttttttgcg tgttttatgg ggttgtttgt gaggtcgtgt gaattagagt 151440 tcggttggga agttatatgt tatttggatt ttgatttttt ttggtagtat gattttagtt 151500 aatacgttta attatgtttt tttttgtaaa atgggttaat agaaatgttt attcgagata 151560 tgatgagaaa taaaggtgtt tatagagtaa agtgtttaga acggttttgg tatgatagga 151620 gtttatatgt tagtgttgtc gttggtatcg ttattattac ggcggtattg gttgttttgt 151680 tttttttttg tttttgttat tttttttttt tagtaggttt ttatttattt gtttatttat 151740 ttatggtcga ggtttcgttt gtgttaggtt tggtgttgag aacgggggta gagagatggg 151800 ggttgtgttt tgttttttga tttaagggtt ttttttgtaa tgtgaagttt ttggagattg 151860 gatttttagg ttgttttatt agtttttttt taggttagtt taattttttc gtgttcgttt 151920 tttgagttgt tagaggaaga gagcgggagg aaggatggag tggggttttt gtggggattg 151980 agcggggggt gtgtgaggtt ttggaaatgg tgtttgcggt atttacgtag tattagtttt 152040 tgttgtagtt gttgtttgga gaatattttt ggattttagg atattgatga tagaaggtgg 152100 aacgtttttt ttggaagtta ttaagagggg attatcgcgg cggttgagta gagttgttga 152160 tttgtgagtt gtggtttgat tatagttatt gtttttatga gcgaggtttt ttgtggtttt 152220 ttttttagga atttttggtt ttttggtagg ggatagttta gggttggggg tgggtagtgg 152280 tgtttgtagg tttttttgga gttagagaat tttttgtcgt cgtggcgggg ttgttttttt 152340 ttgttttttt tttttcgttg tgtttttagt tgtttcgata ggatgttttt ggtttgagag 152400 atagaaattt taattttgaa tggttttagt ttttaagaga atttggagtt tttttgtgta 152460 aaatgagatg ttttgagtat cgaggatgtt gtgggggatt ttttatttta ttatttttag 152520 tcgtggtgtt tttttcggtt ataggatgtt gtagttacgt tgtagggaag gagagttttt 152580 ttttttgtga gtttagggag tttttttatg tagttttttt attggttatt gtttgagatt 152640 cgatttggtg gtttttgttt taaggagtag aaagggggtt cgttaggtta gggtggggtt 152700 gggtgcgagg atttttttcg gttaataggg tttgtttagg tgttcgtttt gttggggtag 152760 tagggaaggg atttatatgt ggtattggga tacggagagg tttttgtgtt tgtgacggtt 152820 aaaagggatg gcgttttagt tacgttttta tttatttcga ggtttagtat ggttatgtcg 152880 gaaatagtag tatcgttttt tttattgttt tggtttgttt ttaataggtt agaggggtgg 152940 ggttggagcg ggcgtttgat ttgtggttgg atttagttgt tcgtggatag gttgtgagtg 153000 aatttgtaga ggaagggaga tgggaatgtc gggatttttt tttgtatttt tcgaattttc 153060 gttttttgtg agttagatgg ggagtgtatt tttgtttttt ttttttgggt attttttgcg 153120 tttttcgttt taggtatttg atgttgtttg tttatttttt ttttttgttt ttttcgttgg 153180 ttttttttat atggttttaa ttaggatttt tcgttcgttg gtggatgggt agagagggga 153240 gtttgttgtg gggttttttt cgatcggggg attttttagt atagagtttt ttggtttttg 153300 tagggacgtt gtgtgtgttt gtgtgagttt ggcgtgttag aagcgttaag ttgtagttgt 153360 tttgtgcgtt ttttatattt tttatttttt aaaggttttg ggtttggtgt ttgtgggttg 153420 gggatttgtg ttggggtttt taggaggttt ttggtgggag aggtagggtt tttttttttt 153480 taatttgggt aattttgttt tggtttgttg tttgcggaaa gtgttttagg atacggtggt 153540 aggattggtt ggggttttgg ttttaggttt agttttagtt tttgttagat ttattttttt 153600 tgtgttttcg tttattttgt ttattcgtag ggtttgtagg agtattttga gagttggtag 153660 ggtggtttgt tcggcgttcg tatagggttt gttggtgggt ggttgaggtt gcggtgaggt 153720 ttttatggtt ttttcgtttt gtatattttt tttttgttgt gttgtttcgt tagtatatga 153780 gttcgtattg tttttgagtt tgtagtttgt tttttttatt aggtggttaa gtagggtggt 153840 agttagggtg gtagagtttt attggtttgt aggggatttt ttgtgggttg taggtagttt 153900 tttgtggttg aaggtgtttt ggtaggattt gtattatgat tttcgttaaa gtttacgttt 153960 aaggtatttg tgggtatttt cgttttagac gtgagggttg gtattttttt ttgtacgtga 154020 agtaaaggtt tgtttgaagg agcgtgtgga agtttgggtg tgatgaaggt aaggatcggt 154080 ggtttatttt ttttgtattt ggattttggg tggtaggttt ggggttttta gtttttaatt 154140 taggagggta gttagtcgtt ggaattaaga gtgaatttta gttgttgttg ttatagttgg 154200 agggaagagg ggaaaggagg cgttgtaggg gagtagagat tttatttttt ttttgtcgat 154260 attaggttgt cggtgttgga cggggttttg gtaatcgtgg taggagtggt gatgttcgat 154320 gatggtaata agggtttttt gaggatttcg agttgtttta agggtttttt atttggagta 154380 agtatttttt ttaatttttt taataatatt gtgaaattga ttttgttgtt atttttattt 154440 tatcgatgag gaatttatag tttagagatg ttaagtaatt tgtttaagtt tttttttgag 154500 tatggtagag ggagggttcg aatgcggaaa gtttggtttt agtgttttta tttttaatta 154560 ttgttattta ttttttcggt tagttttttg attgtaaaat ttgaggttta gaggagtgta 154620 gtgatttggt tagtttcgta cggtaggtta gtggtagagt tgagtagtgt tttttatgtt 154680 ttgattttgt ggttttttga ggtggtttat ttttaaatac gttttttatg gtggttttgt 154740 tttttttttt tttttgaatt tgttagtttg tgtttaggta gggggagaag tagagtaatt 154800 atgtcgggcg ggtcgtcgtg ttttagtgtc gtttgtttta tatttgattg gtagtagagt 154860 ggtttttttt tggtgtggtt tggaggtgtt agtggttatt tattagtata gtttagtttt 154920 atatatgtta tttttaaagg atgttgatat agaatgaagt agttagggga ggcggacgtt 154980 ttggtacgag ggtggcgttt ttggtaattc gtagtgttgt tgtttgtggt tgtttttggt 155040 tggtatttta tttttttttg gttgttttgt agttatttga gggaggttag tatgtcgttt 155100 ttattttagg atagtgtgaa tgtagtagcg taagtttgtt agcgtcgtat tgcgggattt 155160 ggaggttttt gtttttgagt tttgtttttg tgtaattttt aaagtacgga ttttttaggg 155220 gtttttattt ttttatttgg aaaaatttta tatcgtttag ggtttgaggt agggttagag 155280 tatggagacg ttgttggagg attaagggag aattgagcgc gtgttttttt ggttttagtt 155340 tcgtgtgtgt gtttatgtat gggtattttg ttatttatat tggtttttac ggttgggtgg 155400 gagttgagtt gagttcggcg gttgtttttt tattttgcgg gtttggttgg ggagtgtgag 155460 gatgtttgtt ggaagttaac gtgtacgaaa gagttaatgg tggattttat ttttttagtt 155520 ttttttttag tttttttagg gaaagggtag gaatagagag gttttatttt tagaggaagg 155580 ggtgggcggg gatatagcgt tgttcggtat agtttttttt gagttatttt gtatgtttta 155640 ttttatcgat ttttgtagtt tagttgttta gagcggattt agaaggtgga gagagggttt 155700 ttaataagta gaggatggag tgaatgtgag atttattatt gggatttggt aaagtaaaga 155760 gttttatttt tttttcgtag atgggacggg ggcggggttg gagttagcgg ggtgggggta 155820 tttagtaaga gttttttttt atttttttat tttttttgtt atgggttttt ttttttacgt 155880 agatttttag tttggaatga ttagtgttta gtttttttcg tttttttttt gtttcgttgg 155940 agggagtgat ttggtttttg gtttcggtta tttatatttt ttgttttgtt gtattagttt 156000 cgtggtaggg gttgcggcgg aggtgggtaa aagtcgtttt cgggtagtta gtttttattt 156060 tgggagtgat tgaaagtttt tgggggtttt tgtagggtga gttgtttatt ttggttttgg 156120 taaggatatt taggagaggg ttagggtgtt tgtatttggg gtatagtata aagaatagtc 156180 gtaagtgttt tttaggtagg agggtgtcga agtattggga agttgggatt tagaagtatt 156240 gtttggggtg gtgagtggaa gatgtaggat atagatttac gcgattgtgt agattatttg 156300 gttttatttt ttcggtttat agtggaggaa attagaggtc gagagaggtg aagtgagttt 156360 tttggggtta tatagtttag ttaggtttag ggcgtcgatt ttttgttttg ttttttcgtg 156420 tttattcggt tggtattagt atttttgttt tgatattttc gtgtggtagt tgttgtgatt 156480 ttgtgatttt tttttatttt attttagtgg ggttttgcga gggaaagaag aatgttttat 156540 gtagaagtgg ttggaaagta agaagtttgg agagaagtga ggtttttgtg gtttggtttg 156600 agtttaggat ttatggtttg gtttttaggg atggagtatc gatttttttt ttttatattt 156660 ttattttacg tttttaggag ttttttatgg ggaagtcgga atggatttgg gtttagagat 156720 tgtaaattta ttttgttgga tgtgtggttg tttttatgta attaattttt ttacggagaa 156780 gttaggggat ggtttttagt attttcgggg gttttttagt gaggtgggag gatttcgaga 156840 ggttaggagg ttgtttaaga ttttttgttt tttagggatt aggtgagggt ttgtcgattg 156900 ttttgatttt ttgatgtttt tggtggggag attttagagg ggtttgtcgt tattatcgtt 156960 agtggttttg gtttgtttag ttattttttt ggggtggtta aattttatgt tgtaaaagtt 157020 taagtgaatt ttagtagtgg tttgggagaa ttatttgtta cgagttaagg atggagtttt 157080 tggggaggat tttttgttgt tttttaattt ttttcgggta tatttttttg tagttttatt 157140 ttttgtaaga aagttaggtg tttttcgaag tttttttttg gttttaggtt agaggtgata 157200 gtgggggttt tttgtttgcg ttggtgattg tggttggttg ttggtgtttg gttttgtttt 157260 gtattgtgta tttattgaag gcggtattat tcgggttttt tcggtggtta tgtatgggtg 157320 agtagtttac gatatatttg tttttagtat cgtgtgggtc ggggttttta gaggggttga 157380 gggtttggat ggttttgtag gggggtgttt ttggttttgt gatcgaaagg agttgaaggt 157440 ttggagaagt cgttgggtcg aggttagttt ttatagattt ggcgaggagg gaatagatgt 157500 ttacggagtt gttttaggta ttgtatatat tgttttattt tgcgttgata gttaagaggt 157560 tggtttttcg tcgattttta ttttatagat aatgtgtttt tttagttttt tagtggtgga 157620 gttaggattc gaatttacgt aggtagtttt ttgggtttgt agttttattt tttatttttt 157680 tttaggattt atgttttggg gttggtagga taatgatttt tagagttgag tatattttaa 157740 tttttagtat ttgggattac gttaggtgat atggtagggt tagttaaggt tattaattag 157800 ttggttttaa aatagggaga tgattttgga tgatttatac gggttcgttg ttattataag 157860 agtttttaaa agcgtaatag attatttgag gggtgtagtg ggagaggttt ggaaggagga 157920 aggaggttat aagttaagaa atgtaggtga atagaaaatg taggaaaacg tagttttttt 157980 tgtagtttcg ggagggtgcg tagttttgtg gatatttttt ttgtagttta gtgaggtgga 158040 gtgtgggatt aatttgtgtt gtttgatatt ataagtgtgt ggttatttgt tatagtagtg 158100 atgggaattg aatgttatta ggtagtagtg tttttatttc ggaagaatta ggataaattt 158160 ttttgtggat tttaagtttt gggagatttt gggttttttt ggattgtttt agttttgtaa 158220 ttataggaaa ggttttttat gtttgtttgg gagaagaaaa tttcgtagta aatttatttt 158280 tttttttgat aaatgaaggc gagggtgtgg gttggatata tgtttttttt ttgtggattt 158340 tttttgtttt aatatttaga attttgtagt tgaaggagat tttggggggt tgtttgtttg 158400 atttgtaagt gaagaaatgg aggtttaggg aagttaagtg attggtttag ggttatgtag 158460 agttatgttg gaatattaag ttagatagtt tagtttttgt tttaaagtgt tttttttttt 158520 ggttggggag gagggttgga gggagtggat ttcgagtaat agtagtattg gtaggggttg 158580 gaagagtagt tattgtattt aggtgttgga gtttttggtt attttttgta ggaattaggt 158640 gatttattat ggtataggtt tttttttgtt tatttgtagt tttgggggtt ttagggatta 158700 gaggatattt tggtttgagg gttggggttt gagagaagag atggaagtat ttttagtttg 158760 gtttgttttc gtggcgtttt gtaggtatat tcggtagttt aggggtttta gagaatttgg 158820 ttggtgggcg tttttatttt gtcgtagttg tattttgtgg ttagtagttt gtaggatttg 158880 ggttgttgtt tgtggttttg aaatagttat tttttgagtt gagtggggat taggtgagta 158940 gatttttata ttttaattgt tgtgattttt ttgttttgga ggttggtggg tagtttggtt 159000 ggtgttttat ggtattttat gatcggtttt gttattaggt tcgtgagttg tttttttttt 159060 ttcgggtatt ttgaacggtt tttttgagag tttcgttttg ggttttcgtt tttgtaggtt 159120 ttcgttgttt ggggcgtttt ttttttttgg aagttgggtt tttttgggga tttattaaga 159180 agggttttgt cgagtgttgt taaattgttt tatttggttt ttatttgttt tatttattat 159240 tttattttaa tttttatgtt ttttttttgg ttttaagatt tgagtaggta gggtttgtga 159300 ggtattttag gttttttgat gttgttagta tttaggggat tgttagtata tatgtaggga 159360 gggaaggaat gaaggaagag atgatttggg gagtttttta gtttttattt gtaattggta 159420 tattgcgata aaatatttat ggtattttat tttttttata tatttttttt ttaaatttat 159480 ttttatttga gatggagttt cgtttcgtta tttaggttgg agtgtagtag tataattttg 159540 gtttattgta atttttattt ttcgggttta agcgagtttt ttgttttagt tttttaagta 159600 gttgggatta taggcgttta ttattacgtt cggcgaattt ttgtattttt agtagagatg 159660 gggttttatt aagttggtta ggttggtttc gaattttcga ttttaggtga ttcgtttgtt 159720 ttcgtttttt aaagtgttgg gattataggc gtgagttatt gtatttggtt ttcgtatatt 159780 tataaaagag aatttgttta gaaaattttt tagatgtatt tttagggttt taaggtatag 159840 atatatgaag tttgttagtg agtagttgtt gtttattttt tttttttttt taatttagag 159900 cggtttgcgt tttaagcgga tagttgtttt tttttttttg gttttttgtt gtttacgttt 159960 ttatagaagt agggagaaga ggtaggaagg tgacgcgtga ttattcgttg ggcgttcgta 160020 tagtgtcgtt tgtataggtg ttattttttt tatttgttat ttttttcgtt gagttttttt 160080 ttttttttgt agatgagaga gtattgtttt ttagaggtta agaaatgggt ttagagttat 160140 ttagttgatt agcgtgtagt tagatttgaa ttatattttg ttgattttta tgtttgtagg 160200 tttggtttga tgagatggat agttgggtgg tggagatttt gagattttgg atggttttta 160260 aatagggttt gtagtttttg gatagggaga gtttggtata aagggtttgt ggagtgagtt 160320 gggggagaag gtggtttagg gtttttgttt ttgaataaat agatggaggg gttattttag 160380 cgttttttta gtttttggtg tgttgggttt ttggttttgg gaggagagaa tggagttggt 160440 ttttattttg ggttgggttg gtttgggttt aatttagata agttttttag tttgttatga 160500 gtgatatttt tgtttgtttt ggtgtttttg ttaaaaatat gaagggtttt agaattttta 160560 tttcggtttg tttttttttt agatttggag tgggtttggg gttgataata gttttatgtt 160620 agatagtttg agtagttatt agtgttatta ggtttgatat tgcggttttt gtttcggagg 160680 gaaaaataag gttttttttg ggggattttt tgttagtttg tgaaaatagg tttggagtta 160740 gttagcgttt ttatgtttag atatttcgtg tggtttttaa agtgttttta tgttgttagt 160800 ttatatgatt ttttttaaaa ttttataagg gagggtagga agtttgagta atagtttgtt 160860 aagtatttat atagtaggtg gttttattgt tttttattta tagataagta aattgagttt 160920 tagggtggtt atcgtttgtt ttttaagtta tttagttatt tagttacgga agaggttatg 160980 attttttata ttttagtgaa gttgaagatt ttttttttcg tttttaaaaa tgtttatttt 161040 ttagggtagt gaatatttgg tgtttttgtt tagcgtaaga ggtgaacgtt tgttattttc 161100 gttttttttt ttttattaga tttgattttt tttttgtgac gggaatattt tgtaggtagt 161160 ttgttttgtt tttatagatt ttgagaaacg gggtttaaat tgtcggttgt gggtgggata 161220 ggcgatattg tagtgaagag gtggagtatt tttgtagcgg ggaagaaata tatttttttt 161280 atttttttag gtttagtgtt tgggggtttg tgaattaaat ttatttaaga taaattaatg 161340 agagaaaaga tagatttaat tatatacgta tgggatttta ttgaaaaacg tgatttaaaa 161400 gagtaggtag aaggtggggt tcgtgattgg ttcgaaggta gtgagttatt ttagttgatt 161460 gtttatagtt agttatagat tagatttttt gttttattgt tttttttttt tttatttgtt 161520 ttgttttttt tgagttagag ttttgtattg ttgtttgggt tggagtgtaa tggtacgatt 161580 tcggtttatt ttaattttcg tttttcgggt ttaagcgatt tttttgtttt agtttttcga 161640 gtagttagga ttataggtat ttattattac gtttggttaa ttttttgtat ttttagtaga 161700 gatagggttt tattatgttg gttaggttgg ttttaaattt ttgatttcgt gatttgttta 161760 tttcggtttt ttaaagtggt gggattatag gtatgagtta ttgtatttag ttaattagtt 161820 ttaaaaaaaa aaaaaaaaaa aaaagaattt agggttcgta tattatttta ataggaaaaa 161880 aggaaggggt gaaagtatat attatgggtc gggtgcgatg gtttacgttt gtaatttcgg 161940 tatttcggga ggtcgaggta ggtggattat ttgaggtcgg gaatttaaga ttagtttggt 162000 taatatggtg aaatttcgtt tttattaaaa atataaaaat tagtcgggta tggtggtgta 162060 tatttgtaat tttagttatt tgggaagttg aggtaggaga attgtttgaa tttacgaggc 162120 ggaggttgta gtgagttgag attatattat tgtattttag tttgggtaat agagtgagat 162180 tgtgttttaa aaaaataaat aaaaaaaaaa aagtatatat tatggtaaaa taaatgagtt 162240 tttggaaaga taaataggtt tttaggagtt gagatgggag atgtgaagtt ttgtgataat 162300 gtttttttag gtgtggtgtg gaaattattt atatttttta gggaagagtt agttgttttt 162360 agggagtaga tttgggtttg tatattattt taatagggga aatggaaggg gtaaaagtat 162420 atattatggg ttgggtgtaa tgtgtttagt gtaggaggta gacgtggttt atggttgttg 162480 ttgaaattag tgtagggttc gattgttttg tattgagtgt tgaggatttt ggttttgtat 162540 tagttatgag tttgtagttt tgggatatat ttgatgttgg tttaagggga aatgaggttg 162600 gaggggtagg gtggttggat tggatgtggg tttggggtta ttgttgattt ataaagtggt 162660 tattatacgg gaataataga gttggttata gattataatt agtaatatta tttaaaagta 162720 aggttatatt tttaataata agttatattt taagttatta ttaatttata aaatatattg 162780 ttggtataat gatagttttt taagaaggat ataaaaaggt atgttgggtt gggtgtagtg 162840 atttacgttt ataattttag tattttgaga ggttgaggtc ggcggattat tttaagttag 162900 gagtttgaga ttagtttggt taatatggtg aaattttgtt tttgttaaaa atataaaaaa 162960 aaattagttt ggcgtggcgg cgtatgtttg taattttagt tacgggggag gttgtggtag 163020 aagaattatt taaaatttgg gaggtggagg ttgtagtgag ttgagatcgc gttattatat 163080 tttagtttgg gtaatagagt tagatttcgt tttaaaaaaa aagaaaaaaa agaaaaaaag 163140 taaaaaggta tgttgaaggt atttgtttgt ggaaagttgt aatttgacgg gaggtagggc 163200 gagtattttt tagaaaggtg gaaatgggtt tttttgttat agagatttat aaatatagat 163260 tgaggtttgt agtttaggag atttaaaaga ggtaaaggtg aataagagtt aaggttttta 163320 agttagggtt tgattttggg ggtgggggtt atatatgatg gaggatgtta ggagggtttt 163380 ttggaggtgg tgatatttat taggggggat tttaggtggg gtttgcgaga tagtaggatt 163440 tggttgaaga gcgtaggttt tttagatagg agtgggaatt taggtttgaa aatgagttgg 163500 ttagattgta ggggttttcg aatgtaaggg aagaatttta attttaatag aggagtttgg 163560 gaagttgttt gggaaaagga gtgataaagc gggaggggtt ttttagtaga gttttgtatg 163620 ggtaggaggg agcgagatgg gaggtgggtg ttggtaaggg atgattttag tggtttaggg 163680 gagtagttat agggtggaaa ttaattttgt ggggtttggg taggaaggga ttgatttgag 163740 atatcgggaa gaaatagtta gtaggatttt ggtgagaggg ttgggggtcg gggagggggg 163800 tgtggagagt gggagtttga gtttttgaaa atagatagtg ttttaagggg gagatttgag 163860 gtaagatgtg gagaggtagt tgagttggga agttggaacg gaggtgtggt tattttagga 163920 gattaagtta gggggcgagg ggatttttgg gagttattta gattttagta ttagggaata 163980 cggaggggag aaggagggga gaagaattag ttggtgcgtg ttaggtattg ttttcgaggt 164040 tagatggggt ggggttggat attggttatg aggatttttt taagagttgg gttaatagtg 164100 agacgggcgg atattagatg gttcgggtta agaagtaagt gggcggtggg aagttagaag 164160 tcgtggtgta gatttatttt gagaggttgg gttgtttaga tagggagaaa gtttatagtt 164220 tgaggaggta gataggttaa aggaagaggg tttgtttgtt tttgagattg gggtattttg 164280 aacgtttttt taggttaagt gagaagaaat tagaagagga atatgttatt taaatgtgtt 164340 gaaatagttt agtagttgcg ttgttttata gaaaatgtgt agaggttttt ttgttttatt 164400 atgtttgttt ggggacggtt tttattcggg ttatttaggg tttttttagt ttgttaattt 164460 aagggtggta ggagttgtgg gtgtttttag ttttttttta aggttggttt gtgggtagaa 164520 atgtgggttg tttcggggcg ttatagttat aaatgtatat tagtttttag aattatattt 164580 ttgtttttta gttttttttt tcgtattttt atgtagaagc gcggtcgtta gtttataaag 164640 gatagggagg gatattgttt ttggtatttg atgggaagta tttgttgtat tttattgggg 164700 tgttgtttag gatggattgg aaaagagttg gtaggaaggt tgagttttgt gtttataatt 164760 tggtttggtg gtggtcgagg agtttggtag gagtagagtg taggatttgg gaattggggg 164820 ttggtgtatg tgtgtacgta cgtgtgtgtg tgtgtgcgtg cgtgttgggt gggtagggag 164880 gaagttgtga aattatattt tttttttttt gttgttgtgt tgttgtgtgt tttagtagta 164940 cgtgggtgtt attatatttt ttagtaggtg ttaattttta agattgtttt gggttttttt 165000 tttagttggt tgagttggag gtgggagttt taattgtttt ttgtggtttt tagagtggga 165060 ttttgttgtg ggataggttg gttaatggtg tttttttttt tgtgattttt ttgttgggtg 165120 ggttacgagg aaggattgtg ggtgttgttt atagataggt ggatatgtgg taaggatatt 165180 ttgggatttt ttttttgacg ttttttgaag ggggtatttt tttagttttg agatgagttt 165240 ttgtggatgt gggaagttta ttattttaag agtagtagtt ttggaaaatt taatatagaa 165300 tttcgagtag gggcgggaag gggttttgtt tcgtttattg gttgtttggt agagttttgt 165360 ataaggaagc gtttgtgttg ttgtgggcgg aggaatggat tgagggttat attcgttttt 165420 tgttgtcgtt gtaattgttt attataaatt tagtggttta aagtaataga ggtttttttt 165480 tttatagtgt taagggttag aagtcgatta gttttatcgg attaaagtta aggtgttggt 165540 agaatttatt tttgtttttt ttagttttgg gtgggaggtt ttgttggagt tttttggttt 165600 gcggttgtat ttttttagtt tttgttttta tttttttata gttttttttt tttttgtagt 165660 tagatttttt tttgtttttt tttttttttt ttttgagacg gagttattta ggttggagtg 165720 tagtggtata attttggttt attgtagttt tcgttttttg ggtttaagcg atttttttgt 165780 tttagttttt cgagtagttg ggattatagg tatgtgttat tatatttggt taatttttgt 165840 atttttagta gagatagggt tttgttatgt tggttaggtt ggttttgaat ttttgatttt 165900 aggtgatttg tttgttttag ttttttaaag tgttgggatt gtagttatga gttattatat 165960 ttggtttgtt ttttttttaa aggacgtttg tgatttgggg tttatttggg taattttttt 166020 attttaatat ttttagttat atttatagag tttttgttgt tatatgaggt aatatagttt 166080 gggaagggag agttatttag tttattttag gggtttgtgg tgtattttag ggtttttttg 166140 attttaagat ataaagtaag aaaataaatt ggtttaaggg gaaaaaagga tacgttgaat 166200 tttgttgttt taaatgtata tttttttatt gtgttaaaat gtatagaata taaaatttgt 166260 tattagtaat attgagtata tttatagtgt cgtgtaatta ttagtattgt ttagcgttag 166320 aattttttta ttattttaaa gggaaatttc gtatttatga aggatttatt ttttattcgt 166380 tttttttagt ttttggtagt tattagaatg ttttttgttt ttataaattt atttttaata 166440 agtgtaattt tgtgtgattt taaaataaat aaatatgagt acgatgagtt gtttattgga 166500 aggatattta tgcggggagg tcggcgtgtg gagtgcgtag gttttcggac gggtaggagt 166560 tgaaggggcg tggatgtgtc gttttttttt ttttttgttt tttttttggg gttattgttt 166620 gagtattttt ttttgtaaat ggttttaaat aatgttttag tttttacgtt tgtatcgttt 166680 tttagtttta ggatttttta ttaaaaaata ttttaagttt tagatttatt tttgggaaaa 166740 ttttaatggt tttatttttt tttttgagtt agttagattt tatggtttgt ggcgggttgt 166800 ttttgagttt tgagtatttg tgagttaggg aagtaggata ggtatattta gggaagggga 166860 agagtcgtcg ttagttatag taattgatat ttttggaatc gtttaagaga tatttagcgt 166920 gtgtttaaaa tatttatttt tttttttgtt tgttttttga gacgaagttt cgttttgtcg 166980 tttaggttgg agtgtagtgg cgtgatttta gtttatcgta attttttttt ttcgggttta 167040 agcgattttt ttgttttaat tttttgagtg gttgggatta taggtatata ttattacgtt 167100 tggcgaattt ttgtattttt agtagtgatt gggttttatt atgttggtta ggttggtttt 167160 gaatttttga ttttaggtaa tgtgttcgtt ttggtttttt aaagtgttgg gatgataggt 167220 gtgagttaat atatttggtt atatttattt tttaggagaa gttttgtatt ttttgaaagt 167280 gaaatgtttt taggcgggtg atattgatgg tgggatttgt ggttttatta gtgttttatg 167340 agagatgtcg ttgtgtgttt tattaagttg tattttattg ttttttaaat gtggtttgta 167400 gatatggtgt cgagaatgat ttgggaggtt taaattataa tatggtttaa attaatagtt 167460 ttttgatgat ttggtattat tttaggatta aattgagatt attcgaggat gggcgtggtg 167520 gtttacgcgt gtaattttag tattttagga ggttgaggcg ggcggattaa ttgaggtttg 167580 tagtttgaga ttagtttggt taatatggtg aaattttatt tttattaaaa atataaaaag 167640 tagtcgtcgg atatggtggt gtacgtttgt agttttagtt atttgggagg ttgaggcggg 167700 agaattgttt gaatttagga gacggaggtt gtagtgagtt aagattacgt tattgcgttt 167760 tagtttgggt gatagagtaa gattttgttt ttcggtaatt aaaaaaaaaa aaaaaaattg 167820 agatttttcg agttgtattg tttagtatga tagttattgg ttgtacgggg ttatttgaat 167880 atttgaaatg tggtgatttt aagtggagag gtgtcgtgtg tgtgaagtgt attttgggtt 167940 ttagagtttt agtaaggggg aaagaaaaga atattaaata tttgttattt ttatattgat 168000 tatatgttga attgataata ttttgggttt tgttaagtga atgatattaa aattaatatt 168060 atttgttttt atatttttta atgatttttt tttttttttt tttttttttt ttttttaaat 168120 atggggtttt atattgttgt ttaggttgga gtgtagtggt acgatttcgg tttattgtaa 168180 tttttgtttt ttaggtttga gcgatttttt tgttttagtt ttttaagtag ttgggattat 168240 aggtggttgt tattatgttt ggttaatttt tgtattttta gtagagatag ggttttgtta 168300 tgttggttag gttggttttg aatttttgat tttaggtgat ttgtttattt tagtttttta 168360 aagtgttggt atgataggcg tgagttattg tgtttggttt gtttttatat tttttattgt 168420 aggtgttgga aaatgtaagg ttgcgtttgt ggtttatgtg tcgtttttgt tggagggttg 168480 gatcgagggt tagtcgagaa ggttttgggg ttgttttatt tgaatgttga gtgtgtgttg 168540 agcggtagag aattttgaga agtgttgaag gatagaggtt ttgtgtgggg gatgtagttt 168600 taggtcggag atgttttttt tgtgttttgg agatttttat ttggtgatag taagaggaat 168660 tattgtaaga ggggcggtta ttttagtaaa gtatttagga tgttggtttt ttagtttagg 168720 aatttagagg tagaggaggg gaggaggttg ggtttggagg agagtagggt tttgggtttt 168780 gggaaaagtt tggggggtta gaaagttggg ggatagattg aggttagagg taaagagaag 168840 aaggttcgga gaggagggtt aaggaagaag ggttttgttt acggggaggg agaggtttac 168900 ggggtagggg cgtggtggga gttgtatttt cgaggttttt tgttgatttt gatatttggt 168960 tagaaaggag ttttttttgg tattttttgt tagcggtttt tggagttgtt ttttaggggt 169020 tagtgatgag ggtgttttgg gttgggttgt agatagtgga aaagataggt tttttttatt 169080 tttagtgttg gggaaattag ttttttggag gaagggggag ttgtattttt tgagtggtcg 169140 tattttttgg tttagacgtg tgtgttttgt tgtaattttg gcgattggtg ttggtggtgt 169200 ttattttatg gatggggaag gttaaatttt atagatattg agtgataggt ttagggtttt 169260 ggattttagt gtttgattta gaatttaggt ttttgatttg ttattagttt tttttttatt 169320 tagatgggaa tagggatttc gggtatgtag ttttttttta gatatttttt cggttttggt 169380 ttggcgttcg gagattagta gtagtagttt tttacggtcg tttattgtga gggtggggag 169440 ggtcgtggga ttaggaggtt ttagggggaa agttggttat gaggagtggg aagcgacggg 169500 ttagatgtta gtgattgttg gttggggagt cgttggacgt ggttggtttg tttggttagt 169560 gtggcgggtg tttcggggtt ttagttattt ttagttacgt gtgggggtgc gggatgggaa 169620 aggtaagagt gtgtggagtt tagttagtat ttaatatgag gtttcgtggg ggttgtttga 169680 gggcgtagtt tttagaattt agtttttggt ttttagaagg tgttattaaa ggtttttttt 169740 tatttgagtg aatttttttt agtttttagt aagttttcgg aacgagttta tttttaggcg 169800 ttttttttta gtgtgggagt ggttacgttt ttgttgggag tgatttattt gggtttagag 169860 gtcgtggtat tgagatgggt ttggtagatt ttagcgttta ggtttagttt ttatagtgtt 169920 agtttttttt tttggggatt tttttgtttg tgtttttttg ggttttagta tattttaggt 169980 ttgtagggag ggggagagga agagattgat ttattggtta ggttttttag gggttggaga 170040 ggttggagag gtaggagttg gattagattt gaatttagag gttttcggag gaagagttta 170100 gggtgagttg cgtttttatt ttttgttttt ttttttttgt tttttttttt ttttatggtt 170160 ttagttagta agtatttggg gtagagggga taaatttagg tggttgtgtt ttagttttgg 170220 ttgtaggttt gaatggtttt ttggggtggt tggttatgtt ttttgagagt ttagttgtgg 170280 cgatgtttga gtaggtaggt gggggagtat ttaggaagta ggggtgttag gtagagtata 170340 aggagagagg gtgtttaggt tagttttagg atttggttga gaggaggggg ttttttacgg 170400 gtatcgtttt tggtaagtat agggataagg gtaaggacgg tatggttaga ggtttttggg 170460 agtttttttt tttttttttt ttttagtagt ttttttttat tttttttagg gattttgtta 170520 ttttttttta gcgtgtggta gttttttggc gtttttttcg tgtttttagg ttgtttttgc 170580 gtcgggtttg tcgttgggcg tttttatttt tgtttgtttt ttttttttgt ttttttcgtt 170640 ttgttttttt ggagtaattt tttatcgagt tttttttttt aggtagtcga ggtttttttt 170700 tatttttgtt tcgcgttttg ggaggttttt tgtttcgcga ttataaagtt tttttgattt 170760 tttgttcggt tttgagttat gtgattcggt gggcgggtcg cggttttcgg cgcgtttagc 170820 gtagttcgac gtttcgttgt tggggtgagt tttgtttttt tgtttttttt agttttgtat 170880 tattggttcg ggggttttta ggtggcgcgg tcgcgaggcg gattttgatg gttatggtgg 170940 cggtgtcggg agttacgttg tttttgggtt tcggttcgag gtcggtagga tcgagcgggg 171000 tttttaggag aggggtggcg gggagttcga tttttacgcg gggattagat tttcggtttt 171060 aaaatagaag aatagggttt tgtgtggtta tagttatttt tttgtaaata tttggttaat 171120 taagttgagt ggttaagttt ttttgttgtt cggagttttt tggaatatgt ttttttttcg 171180 taaggggttt ttttggtttt taggagggtt aggaagaaat tcgaattggt tatcgttttt 171240 tttaaaatta tttcgtttaa gttattattt ttttgggttt tcgaagatcg gttggttgga 171300 ggttggagat agttttaatg ttcgaaatgt cgtaatcgaa gtttttcgcg gcgtcggtat 171360 tgggatttag ggagttgttg ttatagcgta gttttggatt tttggatgtg ttggatatgt 171420 gtagggcgtt tttgggagga gcggggaggg agggtgttgt tggcggggtt ggtttgcgtg 171480 tgttttgttt ttttataatg gtatgttgcg tgtcggttat gtagaggtat gttagtgagt 171540 aggggttgag ggattttttt aacggatttg tttttagagg gtttttttat gttgggagaa 171600 ttttagagat taaattatgt agttaacggg gtggttttcg gttttaaagt agggaggggc 171660 gaggagtttt gtaggtaatg ttatttgttt ttgaaacgtc gttttagtga ttttggggat 171720 tgatttagtt tttagtttgt tgtattttat ttttggtttt tttttttttg tttttttatg 171780 tgaaatttgt tgtgttttgg ttagaggttt ggggaatagt tttttgttta tttaagataa 171840 gtttgtaatt ttttttttgg agaaaaatat gttattcgga agtaggttga gtagtggttt 171900 tttggtaggt ttgttcgggg ttgtggagat agtatttgtt ggattaggat ggagttggaa 171960 tttggtttgg attttatatg agaaaattcg ttggaagagg aggaagtaga aaaaggtttt 172020 attttttaat aatgttgtgg gttttttttt tttatttatt gttattttgt tttgaaattt 172080 aatggggtta cgtgtgtttt tatgaatgtt attttttttg gttaattttt tcggtagttt 172140 taggagtttt tttttaggaa aaggaagaag gtgtttgttt agtatttagt atacgagttt 172200 ttgttggaaa ggtgggattt ttgttttttt ttgggttttt tttaggttga gatgtggtta 172260 aggaaggttt gtggtgtggt tcgttttttt taatgttcgt ttttggagat ttgagttgtt 172320 gttgattttt agtttgtttt ttttgttttt tggttatttt tgtgtcgggg tggttgagat 172380 attattgtat tggttatttt gtgtttttat tagttttcgt ttttgtaggt tgttattgtg 172440 atggtgatgg ggttaattta gttgcggtgg ggaggattta ttgtgtgcgt ttggggggtg 172500 gcgtggggta ttttgggatg agaagatgcg atttttgttt tgagagtttt gttttaatgg 172560 aaggcggggg tatagttgta ggtagaagtt attaagtatt gtggttagat tagtatttta 172620 tgttaaaaat ggttttgttg gtcgggcgta gtggtttatg tttgtaattt taatatttta 172680 ggaggttaag gtaggtagat tatttgaggt taagagttcg agattagttt ggttaatatg 172740 gtgaaatttt gtttttatta aaaatattgg ttaattcggg tatggtggcg cgtgtttgta 172800 atggtagtta ttcgggaggt tgagatagga gaattatttg aatttgggag gtggaggttg 172860 tagtgagttg agattgtgtt attgtatttt agtttgggta ataagagtga aattttgttt 172920 taaaaaaaaa aaaaaaaagt tttatttggg tttgggattt gtttttcgaa tattgggttt 172980 attgtgtttt ataaggattt ttatttcgga agttttagat ttatttgggt aattagagtt 173040 tttgggttga ttatttttta gttttggtta gttttttggg ttatcgtatt tttttaattt 173100 tttgttgtgt tacggttggt ttaagttgtt tttattagat aatgcgaggt atttttatag 173160 gaggggataa tttcgttttt aggagttttt tttttttgtt tttaggtttg gtgtagtgtg 173220 tggttttttt gtcggtgtta aaggttttaa ggttttttta agaagtttgt tattattatt 173280 agtagttttc gttatttggt ttttttgtat atgtaagttt tttttatata tttcggatgt 173340 ttagggtttt cgtttttttt ttttggtcgg gagtgtggga agagggtttt attttaatgt 173400 ttgagagtag ggttaatggt tagggtaagt tgtgggggtt ttttttcgtc ggtttttttt 173460 tgtagttttt attttaatat agagtatcga tattatttgg gttttgggaa gatttggagg 173520 ttgattattt tggaggtttt tagcgtttta tagttatttt ttggggaaga ggttttttga 173580 gggatttgtg gtttttggtt gggattttag ttttagagtt ttgtttttcg gcgtcgagtt 173640 ttgatttgtt tattgagtgt tagttcggtt ttcggatagg tagggatttg ttttcggagt 173700 ttagtagagt tttgggaagt ttttttagga gggttttcga gggtggcggt tatgtttagt 173760 tcgttgtacg tgtgagtttg tttgatgagg aattggttgg gaaggcgcgg gtttaattat 173820 aggtttatga gggttttttt cgtttttatt taggaagtag cggagatttt ggtatattta 173880 gtatttgggt ttgtgtttgt ttagttgttg gtggaattat gggagttttg tttcggggtt 173940 tgtagagtag tagtgggaat tttttttatt ttagtttttt ttagagttgg ttgtttaaat 174000 tcgtcgtcgt ttagtttttt tttttttttt tttattaatt ttgggaatcg tatattgttt 174060 attttatcgg gtttcggagc gggtgtagga agagagagtt taatatttag aggtttgggt 174120 tttttgtagg cgtttgagtt gttgtggttt gagttgggtt ttttgttgga attattatag 174180 tagatttaat gatttgtttg taggagttgt tttattttag tcgatttcgg ggttgcggga 174240 aggggttggg ttttggtttt gttgggggtg gggggttagt gtaaagggtt tgaaaagtgg 174300 tagaggtgat ggtttatttg tttttttttt ggtcggtcgg tttaaacgcg attggttttt 174360 tttttttttt tttttttttt tttttttttt tataaataat attaaatgcg atttgttaat 174420 gtatttattt gggtttagta gttggattat gggtagaagt attttagatt tgttattttt 174480 tttaagttaa gggtggggaa tattttttgt gagattttgg tttttgagcg tttaagattg 174540 tttttggaat tttaattttg ggtcggtttt aggggattga cgttgatgga gttgttgata 174600 ttgattttcg gtttttgtat ggtttttagg aagggggttt ttcgtttttt gtttcgtcga 174660 gtttggttgg tagtattttt tttttaggtt tgtgttttcg gtagggtttg ttgttttcgt 174720 tttgttttgt gggtgttagg ttttaagtat taggtgattc ggttattgaa tggttattga 174780 atagttattt ttgttggtgt ttttagtgga atgtgtatgg acgttttttt ttttttagat 174840 ttttgttttt tattttttag tttttgtttt aggggttatt ataggattag gaggtacgta 174900 gacgtgggtg gtatatttat tgggtagatt tagttttgaa tttgtacgtt ttttttaagg 174960 gggtttttag cgggcggggt tgatggtgtc gttttttttt ttgttattag aacggatatg 175020 aggattgtgt tttgtcgatt tacgttttga gtttttagac gttataggtg tttgtttaac 175080 gagtgtttga atgaatggtt agtattgtgt gatcgtagat ttttaatttt tatttaaata 175140 gtttgtggtt tttgtgaggt tatttcgaga tagttttata agaattttta ttttttttgt 175200 acgtttcgta taaggttttt ttggggggtt ttttagaaaa agggttaaag agtagtattt 175260 tttcggggat ttgaatacga tttttttcgg ggtaggggat tgttttggaa gattttcggt 175320 atcgtttttt atgcgttacg tgattaggag ggttttgggg taggatggtg ttttttgtgt 175380 tttgtgtgtt ggggtcggag gaaatattgt tcgtggtcgg tgttatttgt tagttttgaa 175440 gattaatgat gggttggata gtggttttat tgagtgggag ggagaatcgt tgttgtttgt 175500 agttgggggg tcgggtgggt gggagtcgag gttagggaga atagcgtaga tttggtacgg 175560 agaggtttgg aggaggagta gggggtttta gttatttagg gtgtagggac gttatacgag 175620 gagtaggtgt ggtgtgcgtt tttttgcggg ttttttattt tttggtttcg ttatttgtat 175680 taggttttgt ggtgagaggg tatagagtgg aggaaggtgt cgtggttagg gtaggttata 175740 cgttgtgtta atggattgtt gttatttgtc gtttttgtgg ttttgttgtt aggatttttt 175800 agtattaggt ttttattatt aggtatgggt tttataggta ttattggttt ttcgaagtta 175860 gggatagatt ttatagataa tattgagttt ttgtagttag ggatgggttt ttacggttag 175920 tattagattt tagggattag tatcgggtat ttatagttag ggataggttt ttatggttag 175980 tattaggttt tagggattag tatcgggtat ttatagttag ggacgggttt ttatggttag 176040 tattagattt tagggattag tatcgggtat ttatagttag ggacgggttt ttatggttag 176100 tattaggttt tagggattag cgttgggttt ttatagttaa ggataagttt ttacggttaa 176160 tattagattt tagtgattag tattagatgt ttatagttag agatgggttt ttatggttag 176220 tattaggttt tagggattag cgttgggatt ttggatgatt gaaggagggt acggttgatt 176280 aaagttgtag gagttagttt ggttattttg aggtattaag ttattattgc ggttttaggg 176340 gatttagatt tttttatttg tttttttgaa ttttggaatt agatatattt gggtttagtt 176400 tttgttttcg gggttgtgtg tttgggatgg ttgttttatt tttttgaagt ttagtgagat 176460 ggggacggtt gtatagggtt cggtatagat ggtattcgat ggtatagggt tatttgtttg 176520 tatttatata gtttcggttt tcgttttggt tgcgtatcga gagttttatg tttagatttt 176580 tgttgagttt ttaagttttt ggttatgttt taggtttttc gtgagaagta ttattgtatg 176640 gattatgttt cgggatttta ttttgggttg ggaagtttgt tttatttttt taagtttttt 176700 ttagaggcgt tttatgtttt attattttta ttgtttgagg ggttagatag gggaatttag 176760 tgtgggaggt ttagaggtgt cggagtagac gttaagcgag tttcgtgttt atgcgttggg 176820 ttttggtaga tattttgaat gagttttttt tttaggaagg agattggggt tttagtttaa 176880 gttgtggttt taaattttgt gattaagagt ggagaaaagg taagattttt ttttttagtt 176940 ttttagaata gtcgatagtg gtggaaatat ggggtttata ttgaattttt ttgtaatttg 177000 ttgaagagaa tttagtttat atttttaggg gtggaggttt ggtcgatttg gtagtgtgtt 177060 cgtttttttg gttatagttt attttggatc gggtattttg gtgttttttt ttagtgacgt 177120 agtgaagtta ttatgacgtg tttagttggt gagaaagtgt tttttgtaat gttttatttt 177180 ttttagaggg tgaataagtt ttgtttatta taaataatta tttatagaat atatgaggtt 177240 taatttaatt ttgggttacg gtagcgtttt ttgggtaaat ttacgcgtta ttttagttag 177300 agtttgtgtt tttataggtt ttttggattt attttgaagg ggggttggat tttttgtttg 177360 tttcgatgag agggttgtag gatagttttt agcgagtttt tttgagggtt gtaatttttt 177420 tttttggtat ttttttgttc gttaggaatg ttttaagttt ttagtagaag tttatttatt 177480 atagtcgttt tttattttgt ttattatttt ttttgttttt atttatttag tagatttcgt 177540 gtatagttta gtgtaggatt tagggtggga aggtgtttcg ggtgggttgg agtaaggttt 177600 ttagttaggg cggggtttta aggtgggttt atagttagga ttgtgatttg ggaggttttt 177660 ttttgttttg ttttagtttc ggtatcgtcg ttgtttttgt gtttagtgga gatttattgg 177720 ttttaggttt taaaatttta gcgaggtttg tagataggga ggagttttat tcgagggtag 177780 agtgattgtc gggtttattt gtttgttacg aattacgtgg ttttagattt gttatttttt 177840 tttttttaga gttatggttt tttgtttgaa aaatggataa tgatggttat tatgttaggg 177900 attattttga ggataaacgg ggatgaaatt gaagaggttt agtacggaat ttggatatag 177960 aagtgttaat tgtgtgttat tagttgcggt ggttgttaag gtttaattat atggtagtta 178020 cgggttgagt ggcgggcggg aagtggggag taggagtatg taagatgggt atttttgaag 178080 tttttgattt agtgagataa gtatatattt agttttaaga tggagtgttt taggaaggtg 178140 gagattgtaa aggttttgtg gcgtaggagt gtgagttgta tttttgggtt ttttagaatt 178200 ttattagagt ttagggagga ggttagttta gatatagggg taacgggaga gatgggagtg 178260 agaaaatggt ttggcgtttg gaagtggagt ttggaaaggt gggcgtgggg atagaggagg 178320 gttttggggg ttatgggttt atgcgtttag gaggtggagg tagtgaacgg ggttacggtc 178380 ggttttatac gtggtattat tagttttgtt gagtttgtat ttgtttttta ggttttttga 178440 gtgttattat tatttggtat tttttggttt gatttttgtt ttttgttcgt ttgggaagag 178500 tgagattatt tgtttaaagt tttttagttg tttttaatta ttttggttgt tttttggttt 178560 tgtttagggt tagtcgttga tttgaattgt ttggtgttat ttttttagat ttttggggtt 178620 ttgttttggt attaatagtt atttttattt ttattattta ttcgtatatt tatttagtag 178680 tgttttttgg gtatttattt agtaatatta aggcgttgag atgcggttgt ggttaagatt 178740 cgggttcggt ttgtgaggat ttcgtagttg ttattttttt agagtatagt tttagttagg 178800 tatattgtgg ggtttagaaa gagaaattaa tatattgtgt tcgtttattt tgagttgtta 178860 taaggaatag tcgaggttgg ggggttattt gatttacggt tttgtaggtt gtataagtgg 178920 tgttagtatt tgtttggttt ttggggaggt tttaggaagt ttttttttat ggtagaaggt 178980 gaagggggag ttggtacgtt atatggcgag agagagaatt tttagatttt tttttttttt 179040 gaaatggagt ttcgttgtgt tagttaggtt ggagtgtagt ggtataattt tcggtttatt 179100 gtaattttag ttttttgagt agttgggatt ataggcgtat gttatcgcgt tcggttaatt 179160 tttttgtatt tttattagag atggggtttt attatgttgg tcgggttggt tttaaatttt 179220 taattttgtg atttatttat tttggttttt taaagtgttg ggattatagg tgtgagttat 179280 tttatttagt ttttttagat tttatagtaa ttagattttt cggattttgt gatcgtgggg 179340 agggtattaa attatttatg agggatttat ttttatgatt taagttttat tttttttagg 179400 ttttattttt aatattaggg attatatttt agtatgagat ttggagggga taacgtttaa 179460 attatattat acgtgatttt tttgtgcgtg cgttagtttt tatatttggt taagtagtag 179520 aagttttttt tttgtttttt gttgagagag cggtggggga gaaatgattt agggatggga 179580 ggttggtttt tcgaggggtt ttggtgtttg tggagtggga gtgcgggaag gtttttacgt 179640 tgtgtgtgtc gtgttgggtt ggttttttat agtttatcgt ggtgtttttc gaggattgtt 179700 ggggaggaaa gagttaatta atttggggat ttagttgttg aagttattat taaatttgag 179760 tagtttaggg gttttttttt ttttgggttt tatgttattt agtatagtgg ggtttaattg 179820 aatttttttt tattttttaa ggtttttggt tggcgtggtt ggggtttggg atacggggag 179880 cgagagggtt tgggtttttt ttagatttgg agtgggttta ttagaaatgg tttaggaaat 179940 cgcgggggtt atttttagta gttgggggtt tttgtggtta tttttttttg gttttgttga 180000 gtagttttgg tttttggagt ttttagtaag ggatgtgggg gtttgttagg ttagggtttt 180060 tattgttgtc gttatgtata gttgtatttt gtattcgggg agtggggtgt cgagtggggt 180120 gtttgggagg taggtttttt tttgtttttt ttgtttagag attttgggga tgagttgagt 180180 gagatttttt cggtttttga ttggttgtgt ttttgttgtt attttttatt ttttttaagt 180240 ggaggtttat gatttttttt tttatttaaa agggttattt agtgatttag tagattttag 180300 tttgtgttat ttagggtttt tttaaaaatt tgtggggagg ttgggtttgg tggtttatat 180360 ttttaatttt agtattttgg gaggttgagg cgggtggatt atttgaagtt aggagttcga 180420 gattagtttg gttaatatgg agaaatttta tttttagtaa aaatataaaa aattggttgg 180480 gtgtggtggt acgtgtttgt aattttagtt attcgggagg ttgaggtagg agaattattt 180540 aaatttagga ggcggaggtt gtagtgagtc gagattatat tattgtattt tagtttggac 180600 gatagagtga gattttgttt taaaaaaata aaaataaata aataaaaata aaaatttatg 180660 gggggatttt tgtgtttatt ggttggtgtg aggagagggt gaggagttgt agagaaggta 180720 ttaggttgag gatcgttttt atttttgggt tatagaattg aaggagggga tatatgaaag 180780 atgtttttag attcgggttg gaggttgggg atattcgagg gtaaggacga cgttgttttt 180840 gtttttgttt gtagaggagt gtatagggtt tattagtttt ttgttgttgt ttaagtgata 180900 gttttatgga gatagaattt atatattgtg acgttgattt ttttaaaatt tatagtttaa 180960 tggttttgtt gtatttataa agtgattgta ttagggttat ttagagaaat agaattaata 181020 gaaggtgtgt acgtgtgttt agataaagag atttattatt atgaggagtt ggtttatttt 181080 attatagagg ttggtaagtg ttaagattgg tagagtaaat tagtaggttg gagatacggg 181140 agagtttatg ttgcggtttt ggtgtttatt tgaaggttta agatttagga gagttaatgg 181200 cgtcgtttta gtttcgagat ttaggaaaag cgtatgtgtt agtttgagtt tgaagtagga 181260 aaaatttgat gttttaggtt gaaggcggtt aagcgggaag aatttttttt tatttaggtt 181320 ttgtgttttt ttatttagat ttttaggttt ttgttataaa attataaaga tttgattaga 181380 ataaaatttg agaaaaaatt tttttttttt atcggttttg gatttattgg ttgggatttt 181440 ggaaattaga ttgatagaga ttaataggaa ataagtataa taatttaagt aagttttatt 181500 tgatatcgag tttttataag gaaatgaaga tttagagaaa tcgttagttt gagcggtttt 181560 tgttttgttt tgagataaag ttttattttg tcgtacgttt aggttggaga gtagtggttc 181620 gattacggtt tattgtagtt ttgatttttt gggtttaagt tggggtttag ttgtcggttt 181680 cgggagttgt tttgaattta tttttaagtt ttagtttaga tttttaagta gttgggatta 181740 taggtatgtg ttatttcgtt tggttaattt tttatttttt gtagagatag ggttttatta 181800 tgttgttcgg gttggtttta aatttttggg ttcgagtaat ttttttgttt tggtttttta 181860 aagtgttggg gttataggtg tgagttattg tgttcggttt aggtttgaat agtttttatt 181920 tgttttgttt gttttttaaa tttgtttgtt gtttgttttg agtagttttt ttgtttattt 181980 tttttgtttg ttttttgttt aggttggagt gtagtggtat gatttttgtt tattgtaatt 182040 tttgtttttt gggtttaagt tatttttatg ttttagtttt ttaagtagtt gcgattatag 182100 gcgtgtgtta ttatattcgg ttgatttttg tatttttagt agggatgggg ttttattatg 182160 ttggttaggt tgttttttaa tttttgattt taagtgattt ggttattttg gttttttaaa 182220 gtgttgggat tgtaggtgtg agttgttgtg tttagtttag gtttgagcgt ttttatgttg 182280 ggtttgatga agagtggaaa gtcgtgggaa attgtgatag agtaataaaa gatgagttga 182340 atagtgagtt cgtgggggtt tcggtaagat ttgtgtattg gggttttttt tagatttttt 182400 gtttttggag atgaggttgt tttttttcgt tgggtgtagg gagggtattt tttacgtgag 182460 gggtttatga tttattttag agaaggggta ggttagtgag ttttttttgg atttgttatt 182520 ttttaaattt ttttagttga aaatatttat tatgttaagg tattgtattt tggagtgtgc 182580 gttttaagtt ttgttgtttt taattgatcg ggtgaggttt atttttatta gagtatatag 182640 tttgttttat ttaggttttt gattgtattt tttttttgtt tgtttcgaga atatttatta 182700 gtagtgtttg tggttgtagc gtttatttta agataaattt gtcgggaagt attttgtttt 182760 tattattatt tttatattat tttagtatat cgattttgga aataaaagat attattttgt 182820 ttatagtatt ttatttttag tagtggtatt ttttttaaaa aaaaatggta atttttagtt 182880 gggtgtggtg gtttatgttt gtaattttag tatttgggaa agttgaggta ggttgattat 182940 ttgaggttag gagttggaga ttagtttggt taatatggtg aaattttatt tttattaaaa 183000 atataaaaat tagttaggcg tggtggtagg tatttgtaat tttagttatt tgggaggtcg 183060 aggtcggaga attgtttgaa ttcgggaggt agaggttgta gtgagtcgag atcgcgttat 183120 tgtattttag tttggacgat agagtaagat tttattttaa aaaataaata aataaataaa 183180 atttaaaaaa aaatagtaat tttcgatcgt tgaaaatgtt aaattttaga gaatatagta 183240 tttttataag tgatgttaat attgtttttg attagttgtt ggttgaagat ttatttgatg 183300 aatttgattt ttttagaata gacgatttag atgattttgt tgttttgttt agaaataatt 183360 gtaggaataa tttaaaaaat tttttttttt tttaattttt ttgttttttg agacggattt 183420 tttttgttgt ttaggttgga gtgtagtggt acgatttcgg tttattgtaa tttttgtttt 183480 ttgggtttaa gtgatttttt agttttagtt ttttgagttt agttgggatt ataaggtgtt 183540 tgttattata cgtggttaat tttttgtatt tttagtagag acggtgtttt attaggttga 183600 ttaggttagt ttcgaatttt tgattttaaa taattggttt atgtcggttt tttaaagcgt 183660 tgggattata ggcgtgagtt attacgtttg gttagttttt atatttaatt tttatataga 183720 gtatttagtt agatttgttt tagttttaaa gagcgtgttt atgtaaaatt aagtgagtgt 183780 tggtagtgag ttgaattttt taaaaggtaa aagggttaaa tattaaattt atttaaaaat 183840 atttttatag atatatttag aataatgttt gatcggttat ttaggtgttt tatagtttag 183900 tttagttgat atagaaattt tttttttttt ttttgagacg gagtttcgtt ttgtcgttta 183960 ggttggagtg tagtggcgcg attttggttt attgtaagtt tcgtttttta ggtttacgtt 184020 atttttttgt tttagttttt cgagtagttg ggattatagg tgtttattat tatattcggt 184080 taattttttt ttttgtattt ttagtagaga tggggtttta tcgtggtttt aattttttga 184140 tttcgtgatt tattcgtttt agttttttaa agtgttggga ttataggtat gagttattgc 184200 gttcggttga tataggaaat taattattat agttatatag ttatcgttat taattttagt 184260 atattttatt atttttaaaa gagattttgt ttttattagt taatttttat ttttaatttc 184320 gggtttttag tttttagtta tcgtttattt gttttcgttt ttatgaattt atttgtttta 184380 gatagtttgt ataagtggaa tcgtatagta tgtggttttg gtgtttggtt ttttttattt 184440 ggtagaatat ttttaaggtt tatttatatt gtagtaggtg ttggtgtttt attttttttt 184500 atggtcgaat aatattttat cgtggataga ttatattgtg tattttttta tttgttgatg 184560 gatatttggg ttgtttttgt tttttggtat aattttgttg tgaagaattt tgtagtgagt 184620 gttggtttat aggtttttgt gtgaatatgt ttttattttt tttgggtaat tgtaagatta 184680 tgtggtttag ttaattagtt tttaagttat gtgtttgttg agggatttag gtttggtggg 184740 ggtgtattgt tgtgtttggt tagttaggtg ttgcgagttc gtgtcgtagt tatttttttg 184800 tgttgtgttt tgaggttgtt tcgtcggtat cgggtattgt gagttttagg aggttaaagt 184860 tttttttgtt ttattttgag tttaggtttc gttttatgaa ttaggatgaa tggatattga 184920 attaacgtag ggatgggtgg ggttggggtg gggacgtaga gtgatttcgg gggtttgtag 184980 ttgggttttg gttgttgatt tttagttttt tttgtttgtt ggagtttaga ataagttaga 185040 aaggggaaat gtaaagttcg agtgtttttt ttgtggtaga ttggtaggtt tgggtgggtg 185100 agttatttgt agttagttgt agcgtgagag aggaagtggg aggggaggga gagggtgagt 185160 ttggtgtaat ttatttttgg aaggaggttg ggttgaggtt gggggaagtg atttttattt 185220 ttttgagagg attttttttt ggggttaatt ttaaattaag ggagataaga tttttttggg 185280 ggaggttgga agtgttgggg tttttaggtg ggtaggtttt ttagggttaa cgttttgggg 185340 aagttataag ttattatgtt tttggattgt tatatatata tatatatata tatatatata 185400 tatatatata tatatatata tacgagtaaa ttgtaatata aatgtgtgtt tatgaaagtg 185460 tttattttaa attattatat agtttgtaaa gcgaaggttt tggttcgtat ttgggtattt 185520 attgtttagt tagtcggtag gtagtttgta ttgtagtttg ttattatttt ttagagatgt 185580 agtcgaggag tttagttggt ttggagggtt tagtgggcgt agttttagga aagtggttag 185640 gttcgggtta ggtttttttt tttttttagt tttgggagaa attattatat gaatgtagtt 185700 ttttttcgga gttcgggttg gaagggtttg ggaggggata ggtttttatt ttaggagttt 185760 ttaggtttcg gttgttgttt gtgttagttg cgtgagcgtg agcgagttag gggttattat 185820 tgggtggaag gaagaagcgg gtattttttt taggaggtta tcgttggagt tttatagtag 185880 gttaatttta ggttttgggt tttcgggagg aggagaaaga agagaagtag gaggtgtgga 185940 gggtaggtta ggattagaag gtatataggg tcggggtagt gtgggagatt ttgggggttt 186000 ttttatttaa ttagttaata ttatagcgtt tataagaata cgttattatt gtagttttat 186060 tattttgttt tgattttaga aggtataatt gatgatttta gggaacggag aatttgagga 186120 aggtttcgta ggagagggtt agatgcgatc gagtaaatgt gagtcgtttg taaattgtag 186180 agtgtacgta tagtatcggt tagttttggg gttagtgttt ttttggtgtt tagttcggtt 186240 tttgtatttt ttagtgttcg gttgggtttt gtgggggtta gggttgggtt tggtatatta 186300 gaggattttt attaagtttt tggtagtgtt ttagttatta aatttagttt gttagttatt 186360 aaattcgttt tgtcggtttt cgaattattt tttcgttggg gtcggttatg ttacgttagg 186420 ttttttatgt aggacggtag atggatagac gttgggatta agttattttt gggtcgcgag 186480 acgtttgatt ttttgttggt gttttagaag atgttagttt ttcgtggtat gttttttacg 186540 cggtgtttgg ggattagtgg tttttaaggg gtttttttgt tttagcgtgg ggagtggttt 186600 ggttaaggtt ttagtgtttg gttggagtta ggtataggtt taggtgtatt ggttggaggt 186660 tttttgttta tgggttttgt ttgttttgtg tttttggttt ttattgtgtt ttttgtgttt 186720 ttgggagaga ttttaggggt tttgagttta gtattggggt tggggagtgg gcggggaaga 186780 gggtggggat tagggttttt ggttgtagaa tagttaggtt ttaagttttt attttatttt 186840 ttttttatcg ggcgttttat tttatattga ttattttttg aagaaaattt tttgaatcgg 186900 ttttttattt cggttgtttt aggaagttta tttatttttt cgttttaatg ttttgtggtt 186960 ttagaaggat ggtggaagtc ggaaattatg agttttattt ataggcggtt atatatcgaa 187020 gtcgcggaga cgtcgtggga aaggattttg gttagcgcgg tcggtataga gggagcggtg 187080 ttatcggggt agacgggaat cgtggttgtt tttatgttgg tttgggagag acgaggggtc 187140 ggacgaaagg atagtagatt ggttatttat ttatttattt atttatttat ttatagcgtt 187200 ttattgggtg tttcggacgt gtaaggtttt gtgggtagtg aatgcgatag attttagata 187260 gtaatcggag ggttacgtgt gtaagaattg agggatttag gttgggcgtg gtgttttaag 187320 tttgtaattt tagtattttg ggaggtagag gcgggcggat tacgaggtta ggagatcgag 187380 attattttgg ttaatacggt gaaatttcgt ttttattaaa aatataaaaa attagtcggg 187440 cgtggtggcg ggcgtttgta attttagtta tttaggaggt tgaggtagga gaatggcgtg 187500 aattcgggag gtagagtttg tagtgagttt agatagtgtt attgtatttt agtttgggcg 187560 atagagtgag attttatttt aaaaaaaata aaataaaata aaataaaata aaaattgagg 187620 aatttagtgt agatgagtta tttcgggaaa ataagtggga gttttaggaa tagtatgggg 187680 aagggatggt ttcggtaggg aggatttttg tgggtagttt tgttggaaga gttgaaaggt 187740 agttagagag gttgtgcgtg gatggaagtt gaagagtagg ttaggggcgt gtgttttgtt 187800 aataaagatt ttaagtattt attgattagg tataatatta tgtgttttat aaataaatat 187860 tttatttgat ttttagtatt tttatgagat agatgttatt attttatttt atatgtaaga 187920 atattgaggt atagagtggt taagttattt gtttagggtt atatagtacg tcggtggtag 187980 gtaggatttt ggagttatag gaatttggta tattttaggt gtaatggaaa ttagttacgg 188040 ttttatagag ggaaattatt agattagtaa attttatata cgttttttgg tgttttgagg 188100 aggagggatt cggatagggg tagttaatgg tggtggttgt gagatgtgtt gggttaatat 188160 tgatgagagt ttgggatgga tgagtggatt cggagtaatg gaaatggagg gtttaggttc 188220 ggtttttgga gatttagttg taatagttgt tggttggaga ggttgtttat ttagatgggg 188280 gatggggtgg gaggtaggtg agatgagagt tttagagttt agtttggggt acggttattg 188340 ggtttaagat gtttttagat gttggggttt gatagtgata gtggttgtag atatttagga 188400 tttagtagag ggtttggtat agcggggttt agggatacgt ttgtgagtta ggttggtatt 188460 taagtgtgaa tttggataaa gaaggtggta ttgttggtat tgaatgttta ggggttgggt 188520 gaagttagtt agggagaggg gtttttaagg tattaggatt gatttcgtgg gtgagggcgg 188580 aggaggagac ggtagaggtt gagagaatag ttagagatag gaggaaggtt agtagagtta 188640 tgtatagaag tttggagaag atttgaggaa aggaagggtt gggtggtcgt tattttttgt 188700 agttaggagg taagggtgat ttttgtgtgt tttatttttt agaggattgg tggttttatt 188760 tggttagaat tttaagttta gagatgtatt tgagttttat gttatggtgt aggtagtagg 188820 agttatggag taggtttgcg gggttacggt ttgtttgttg ttttttggtg tttttatttt 188880 gagtttaggg gttgtttgga tgttttgtgt tgtatttttt taggcggtgt tttagagagg 188940 atgaaagtgg ttattttaag gtgtgattag gtagcggttt atgtatattg tttttttttg 189000 gggagagttt gggatggaag ggtatgtgtg tgtttttgag attttttgaa taggttttat 189060 gtatttattt atttatttta ttatttattt atttatttat ttatttattt atttacgtat 189120 ttatttattt atttatttat ttatttattt gttaatttat ttatttattt atttatttat 189180 ttatttattt atttatttat agttatttat ttatttattt atttatttat ttatttattt 189240 atttatttat ttatttattt gtttatttat ttatttattt atttatttat ttatttattt 189300 atttatttat ttatgtattt atttatttat ttatttattt atttatttat ttatttattt 189360 atttatttat ttatttattt atttatttat ttatttattt atttatttat ttatttattt 189420 atttatttat ttatttgttt atttatttat ttatttattt atttatttat ttatttattt 189480 atttatttaa ttatttattt atttatttat ttatttatta ttcgtttatt tatttattta 189540 tttatttatg tatttattta tttatttatt tatttattta tttgtttatt tatttattta 189600 tttatttatt tatttattta tttatttatt tatttattta tttatttttt tatttattta 189660 tttatttatt tatttattta tttatttatt tatttattta ttcgtttatt tatttattta 189720 cgtatttatt tatttattta tttatttatt tatttattta tttatttatt tgtttattta 189780 tttatttatt tatttattta tttatttatt tatttattta tttatttatt tatttattta 189840 tttatttatt tatttattaa tttatttatt tatttattta tttatttatt tatttattta 189900 gttatttatt tatttgttta tttattcgtt aatttattta tttatttgtt tgtttattta 189960 tttatttatt tatttattta tttgtttatt tatttattta tttatttatt tatttatata 190020 tttatatatt tatttattta tttaattatt tatttttatt tttattttag aaagtatttg 190080 aagttgttgg ggtgtgtatt tggaaaatgc gttataagtt tttataggtt tttttttggt 190140 ttttttattt ttttgattgg tttttttttc ggatatgtag gattttgagt agtttttttg 190200 ggaggtgggt gtagtttagg taggttgttt gtaaagttag gatcgaggga gttatattta 190260 aggtattgtg ggtttttaag gcgatggtat tgtgggttta ttgtttttag atttttttaa 190320 tttttaggtt tttgagtagg aggatttttg gggtagggtt tggagacggg aagagaaaat 190380 aattttagtt ttttaatttt tgttagttta ggtgggtgtt gtatggattg ggggtatttg 190440 gaatagttgg tttttttatt tttttttttt atttttttag tttttttggt tataattaga 190500 tagttgtgtg cgatgttttt tttttttttg aaggggttat ttagttaggt ttttatttat 190560 ggtttaggaa tgtgtttttt tttgtttgtt ttttattttt aagtaggtcg tgtttttagt 190620 tttttgttgt ttttgaaggg tttgggtatg gggtagtttt tgtagtattt ttagggttcg 190680 agttgatttg tatagtagaa gggaattggg ggaaagtttt ttttttattt agtatttggt 190740 agggggttat tttgttgtat tttagagatt tttgtttaag ttttgttatt ttagatgatt 190800 ttataagttg ggggaggcgg agttttagtt tttatagttt ttgttgttgt tttattgttg 190860 agttttgttg tgtatttgtt gataggtttg ttgatagtag aaggggttgg agagagggaa 190920 gttttgggtt ttgttttttt taatttttgt ttaggggata tttttgataa gaggaaattt 190980 tagtttgtga tagatggtta gtgtttattt atttacgggg gaattttttt ttttttttgt 191040 aagtttgtag atttgttagg aattaaagga atttttggtt gataggttat tgtggatatg 191100 gttggagggt tggtacgggt tggattttgg ggttgttttg aggtaggggt cgtttttgtt 191160 ggaaggtttt ttggggtggg gaaggtatta gggttatttt ttgatttttt ttttgtagtg 191220 gatttatttt agagtttgag ataaggtaag ggggtagtag aaaatagaat ataaaatagt 191280 tttttttatt atatatcgta ttagaagtta gaggatttat ttttggtttg ttttttttgt 191340 agtttaagtt ttgagagtgg ttttttagga agtgaatggt gatggtttgt aggttagagt 191400 ttgttttggt ttaagattga tgttttaata ggtcgcggag tttgggtgaa aaaatttagg 191460 ttagggaggt ggtgggttgt aaatgaaaga atagaggagg gtttttttta gaaagcggcg 191520 ggtggtgtga ggagtttttg gattttgttt aaatttgatt ttatcgattg gggttaattg 191580 aaatcgtgtt ggtagaaagg taaaattgtt tgagattttt ttttttataa tagaggagag 191640 gtttgtttga aagggtttgg cgagggaaaa gttggaggaa ttttggtcgg tagtaaaagt 191700 ggggattttc gttttttgtt tcgggggcgt ttcggttttt gaatgaatga aagaggaggt 191760 tggatggaga tagatttata ttatttgttt tttttaggtt ttgtaaagga gtatataggg 191820 tttttgttgg tttttttatt ttgttagtta ttaagaagga gaaaatatta ataggggaat 191880 tgtaaagttg tagttttgtt taagttttat agtggaaatc ggaaagagtt ttagttcgga 191940 gaaaaatgta gttttttgtt tttgtaaatt cgtgtttttt tttgggaggt tagagttatt 192000 gtgttcgatt tttaagtagg gttttagagt gttttaggag gggaaggtag agttttagat 192060 tttcggtatt ttaggtttta attaggtttt gaggagacgt tttttgtttt atataaagtg 192120 tgaagtgtaa tttgatttgg agttagttaa taaattagat gagttgtgtg tattttaaaa 192180 atttagtttt tgatttttta tttatatata tttgtataat ttggttattt atatttagtg 192240 tttttatttt tagaagagaa taggaagttt ttagtgatat ttatggagtg tttgtagtag 192300 tttgggtagg ttagtaggaa tataatgtag tgaaaagtag agttgagatg ggaaaatatt 192360 ttgtttttag agttttttag ggatgatatt ttttatcgtt tttgtttatt cgttttggag 192420 tttatttcgt aaatagtaat ttgtttttat ttgagagttt ttttttgtcg gagtttaggg 192480 atggagagta gttggtttta gttttttttt tttatttttt tgttttttag atttattttt 192540 tattttgaat aattgttttt aatttgtttt tttttttttt tagttgtaga atttagaatt 192600 ttgtgtgtgt ggttaaaagt ttagagagtg ttgtaggtaa tgttgagata attttattaa 192660 attttgtaag tttttattat attaagtttg tttgtttttt ttaattttta ttttatttta 192720 ttttatttta tagggatggg gtttcgttac gttgtttagg ttggttttga atttttgggt 192780 ttaaacgatt ttttcgtttc ggttttttag agtgttaagt tattttttta attgggattt 192840 acgggtttag ggattttttg atgaatcgtt taaaatacgt gtgtgtttgt ttgtttgttt 192900 ttaatgtata tttttttagg gagagttttt attttttatt agaggtttgt ggtatatata 192960 tgttttgtat tattgtatta gattgtgaat tttttatatg ttaaagattg ttttaaattt 193020 gttcggaagt ttcggttaat aaatatttaa ataaatgaat tttaaatttt tatgtgttat 193080 tattgttttt attttgatta tttttaagtt tgtagtgtta tttttttgtt attgtgaagt 193140 agatatttaa taaatatttg ttaaatgaat taatgttatg gttttggttt attaggattt 193200 taggattatc gtttattatt attgtttata gtttttttat tattttgttt tagagtagtt 193260 ttttttttga ggtttgttta tttttgtacg tgtgtttagt ttttagtttt gtcgttttat 193320 tatttttttt tttttatttg tattttttga attgttaata gttaataata gttttttttt 193380 ttatttattt atttatattt gaagtgagaa gttattattg aggtttttgt ggattttgtt 193440 agtttaattt ggggcggttt tttggaggtg gagtttttag atgagggatg gatattttgg 193500 tgtttgttgg gtagatttat ttgggagttt tggtaggggt tttagggtag ttttgttttt 193560 ttattttggt tgtgggattt ttggtgtatt agggtttttt aagtaagtat ttgtgttttg 193620 ggagagttat aggtaggttt gagagggttt ttggaatttg ggatttttag ttcggtttag 193680 tagttggtat tattattttt tttgtaaggg aagttatgga aattaagatg ttaatgtgtt 193740 ttgataggtt tggggtggtt ttaagttttg ggaagagttt tggtaatttt ttttggttgg 193800 cgggtagaat ttttttttgg tagtttaggg ttttgttttt agttttttgg gggagagtaa 193860 ttgagggagg agttggaggt taaggtttta gtgttgagtt gtttgtatcg tagttgtatt 193920 ttttgggttt tggttgtagg aattttatat ttttttagtt tttttatggt tttcgaagat 193980 ttggtttggg gagggggtta gtagtttggg gtttatttat ttggttttaa attttggttt 194040 tatcgtttat tcgttttgcg atttttataa ttgataaaag ttttttcggt ttcggttttt 194100 ttatttgtga aatgggataa taatagtggt tattttatag gattgtgtga tgatttatta 194160 gttataatag tttttgagta gcgtttagag taatatttgg ggttcggtgt agtggtttat 194220 gtttataatt ttagtatttt gggaggttaa ggtgggagga tcgtttgagg ttaggagttt 194280 gaaattagtt tgattaatat tagtgagatt tattttttaa aaaaaaaaat tagagtaacg 194340 tttggtatag agagttttta gtaaatttcg gttgttgtga tgagttttgt ttttttattt 194400 gtttatttat ttattagatt ttttgtcggg gtttgtcgtg agttttacgt tgttttgaag 194460 aaagtcgggt tggggtgagc gtgatggatg aggtgtttgg ttttataaat tttgtgtggg 194520 ggggttgtgg tgagaggaaa tcgtatatat tattatttag ttattatcgt ggggagattg 194580 tttggacgta gagagtaggt tttgtgtggg agcggggagg gtaagttttg gttgcgaggt 194640 agggtttttt taggatttag tagggatttg aaggattttg taggtattta gggagatagg 194700 agaggaggag ggagtagttt tggtcggata ttgttttttt agtattgttt gtattaggga 194760 tttatttagt tttaagaagt ttttttgtgg gggataggga gtatttgtta gtttatagga 194820 tttgaagtgt ttttatgggt ttaagttttt gggaaggttt gtaggtggtc gtagggttgt 194880 cgtaggggtg ttggttttag ggtttggatt taggggagtt tgtagaggga gggtagttgg 194940 aggttgtttt agtgtgtatt gttacgaggt aaagtaagga gattgttggg tttacgttgg 195000 gtcggggtgg atggaggtaa ggaagttttc gtcggggtaa gggtattagt tgtagatgtc 195060 ggtagttttt ttttggatac gggtttggaa ggttgatagg gtgtggtgag tgttatcggt 195120 ttttttgtcg tggtttggtt agtggtttta taggttttcg tgggtaggag gaggatgatt 195180 ttgtattttg tttggttatt attggtagtg atagataagg tgtgtgggga tgtggttatt 195240 tcggttcgtg ttttgagagt taggtgtggg ttgggtttgg ggaagatagg ggaatggtat 195300 tgatttgatt ttgagtattt tgttttgggg tgtaggttcg gttgttattt ttttggagtt 195360 gggaatggta ttgggcggtg gtttagggtt ttttgtttta gcggtattat ttttgtattt 195420 ggttagtaag gttgatggga tttgtgtgga tatttttggg acgtagatta ggtagtatga 195480 tatataggga ggggtaggta gagaagggcg gtttttgggt tttggttttt aagttaggtt 195540 ttgtaagttt gttgtgttaa gttttttttc ggtattaggt taggtgggtt agggttagtt 195600 ttggggttgt gatgagtgtg agtgttttta aagtgtgtta tgtttaatag ttgttttttt 195660 tttgggtatt gttttttagt tagatatttt atagttttcg ttttagttat agatagtaat 195720 ttgatttttt tattttcggt aggttttggg gttggggtaa gaatttgtta ttaagtgtag 195780 atgtttttag agggtgttgg tttagggttg cgtggattat agttttttta tttttgtttt 195840 agatttattt gtaattttgg agaaaagatg gtttagtgga cgtttgcggg gaggagggag 195900 ttggttttta ggatgagtag atttgggggt agtttttatt acgggatcgg tgatttattg 195960 ttattagcgt tagtgaatgg tagaggggtt ttggtataag gtttgggttt agaatgggaa 196020 tttgtagaga aattgttaag gtttttcgtt atttgatatt ttcgtttggt tgttatttta 196080 gaaatatttt tgttgtaaga agatggggga gtttgtttgg ggtatggttt ggcgatatta 196140 atttgagaat tttaggttta agtgttggtt tttgggtttt agttgttttt tgagttgtaa 196200 agttggtttt tgggtatttg tggaaaatat tggatttttt attttatttt attttatatt 196260 ttgggatata tgtgtagaac gtgtaggttt gttatatagg aatataagtg ttatagtggt 196320 ttgttgtatt tattggattt tttaatttag ttttattaga aatgattgtt tttttttttt 196380 tttttcgttt tttttttttt tttttttttt tttttttttt tttttgtttt tttttttttt 196440 tttttttttt tttttttttt ttttttttcg tttttatggg gatataattt ttatattata 196500 ttattcgtcg atttagaaag tatagttgag tggtattttt ttataatttt ttataagtat 196560 tatttttaat tttagaacgt tttttttatt ttaaaaggaa acgttatttt cggtatatag 196620 ttattttttt ttttttagtt tttggaaatt attaatttgc gttttgtttt tatagatgta 196680 tttattttga atatatgatt agaattttaa aagatgtgat tttttgtgtt tggttttttg 196740 tagttggaat gtttttagag tttatttgtg ttggcgtacg ttcgtgtttt tttatggttg 196800 agaaatagtt cgttgtgttg atttagtacg ttgggttttt ttacgtattt gttggcggat 196860 gtgttagtta tttttggagt cgggtgtgtt gtgttattta cgggttgtat taggagttgg 196920 ggatattatt gagtaagtta tagtttcggg tatttaggag ttcgtagagt aggagttggg 196980 agggaggtta ggaggtgtat ggtttgtttg ttaggttgga gagatttgta aaaagttatt 197040 ttgagttaga aattagagtt tgaggttttt gatttttagt tgcggagtcg ggagggaagt 197100 tttgtatttt gttttgattg tggggtgacg tgttagttat tgtttaaatt agaatttttt 197160 tgagagtcga cgtgggtatt gttgataatt agtttggata ttcgaaagaa tggaaagtag 197220 ggatttagat agatttttgt ataatcgtgt tcgtagtagg gcgaggtttg gaggtgcgat 197280 ggggatttta acggggtagt tgtcgttttg ttggagttta cggtttttgg ggggggttat 197340 aggtgttaat cgtatattat ataagtagga gtgtgaaatt ttagggttgt taaatttagt 197400 gagggttttg tgttggtttg gttatttata gtggtatttt aggaaaaaaa attattttat 197460 ggattttagt ttttttatta gtaaagagta ggttggattg gaattttgta ttatttagta 197520 tagttgttat ttatgaaatg tggttattta aatttaaata aaaatagaaa tttcgttttt 197580 tagttggatt agtttagtgt taagtgttta gaagttattt gtgaatatat tgtggtaatt 197640 ttttaaaaaa cgaaaattag aattatcgta gtattttata attttatttt tgggtgtgga 197700 tttaaaagaa tgtatagtat tttaaagagt tagagatatt tgtatattta tatttatagc 197760 ggttttgttt atagtagtta gcgggtagaa ataattcgaa tgttcgcggt taaatgaatg 197820 gagaaattaa aggcgggata ggtcgggcgt ggtggtttac gtttgtaatt ttagtatttt 197880 gggaggtcga ggcgggtgga ttatttgagg ttataagttt aagattagtt tgattagtat 197940 ggagaaattt cgtttttatt aaaataaaat tagtcgggta tggtggcggg tgtttgtaat 198000 tttagttatt tgagaggttg aggtaggaga attgtttgaa tttggggagg tagaggtttc 198060 ggtgagtcga gatcgcgtta ttgtatttta gtttgggtaa taagagtaaa attttgttta 198120 aaaaaaaaaa aaaaaagggt ggaatatata aggaatttga tttagtcgta aagaggaagt 198180 taggatattt gtaatagtaa gggtgaattt ttcgggtatt acgttaagtg aaataatttg 198240 gttataaaag gataattttg taggatttta tttatattag gttcgtagag tagttagatt 198300 tagaaaaata gtagaatgga ggttgttaga ggtttggggg atggggttgg ggagttgttt 198360 aatgaggata gtttgtttta taagatgaaa aagttttgga gatttgttat ataataatgc 198420 gaatgtattt aatattattg gattgtatat tttaaaatag tgatcgtggt aaacgttatg 198480 ataattaaaa ggaaaagtta cgtggttagt ggttattacg ttgagtagcg taggtttcgg 198540 acggtgtcgt ggttatagat aatggagtgg gtgattttta ttattgtttt tagttgtttg 198600 agtattatgg tgttttgggg ttaggatgaa agtgtttttg ggtatggggg tttttgtttt 198660 ttttatttgg gagttttgaa ggtagatttt aaagtttatt tggttaggta ggagagcgag 198720 gcgggttttt gtattgtttt ttgcgtgcgt gtttgtttgc gggttagtcg gggtttgtaa 198780 ggtcgttttt cgagggaggg gttgtaggaa tggtttttat ttgtgtagaa ggtaagttat 198840 tgttttacgt taatggtaaa gatggggttc ggttgcgttg tattattatt ttttaagcgg 198900 ggtttttggt gggtaggatg tttggtttga tttgagtttt tgtagtgagt gttggtgttt 198960 gtggagggat ttagttgtag ttgagtcggt ttttttttcg ttttgggttt taggggcgtt 199020 gggggcgaga aaggagagtt tagggggtag cgtttttttt taggttttgt tggggagggt 199080 tgagggatgt tggggggagg tgggggcggg taggggttgg ttttagtttt aggtaaaatg 199140 gtttttagat ttataggtag atggaagcga ttttcggtta cgtgggtggg gattgaattg 199200 ttgtttcgta aggtaaggtt ttatgtttgg ttttaggaag cggttttaaa gttatatggt 199260 ttatggttag atgtagggtt gtgtttttgt ttatttaaag gttttggaag tttaggggag 199320 agtatttttg aagggggagt aggagtagga gtaaagtttt gaaggttttt aggttgcgtg 199380 gtttgggtgg gggttacgtg ggggtataga gagaggagtt ttggttttta ggttcgtttg 199440 tgggtattgt ttttagtagt ggagatgtgt ggattttttt ttggtatttt ttaataagga 199500 attatattgt ttttttgttt ttttaatttt ataagatagg aatttttgtg ttttgtggag 199560 gttgagaaga cggggaggtg tttgtgagga taaattagtt tttagttttt ggtttttaga 199620 gttttttttt tttttatttt tgatgtttta ggtttgggga gttttttttc gatatttttt 199680 gatcgtttta gtgaaatagg tcgagaggga tggtttgaat cggttgggga tgtaggttgt 199740 agttaggggg tttagtgggt attttttgag ttcggttttt gtttcgtaag tggaagggta 199800 gttgaattga agttttttat tgtttttttt ggtttggaag tttgtttttt attttttggg 199860 tagagtgagg agtgggcgtg ggtcgggagg gttgtttttt gtttgggagg gttgtttatt 199920 tgtttgttac gggggatgag ttttttgtag tttttcgtgt tgtggttttg gtttttacgt 199980 cggttttatt tttttgtggt tgtttttgtt gggtgtttat cggttttagg gaaaagttat 200040 ttttttttcg gaggattggc gggaggggtt ttgtttggga gcgtgtcgtg tggtttttgt 200100 tttagcgtag gatgtttgag gttagatttt ttttgggagg taggatgggg taaaagtttt 200160 ttcgtaggta gagtagggtt tggatgggtt taagtaggga cgggggtata gaatagtagt 200220 cgtttagttt gcgtgggagt tgagggttat taagggtagt tttagtttgt ggggattagt 200280 agaggtatta tttttgtgat tagcgagttg tttgtatttg tatgcgtatg tattagtgag 200340 tgtggcgagt ttgaggtgtg ttgggatttg gttcgtgtat tagttagttt tgatgggaat 200400 tagttttatt ttgggtattt ttggaatttt attgtgtggg agtatttggg tttttagtag 200460 gcgtttttcg ggcgttcgtt tttagtttta ggtttttgat tcgtgtgtgg tgttttaata 200520 gtagttagga gtagggttat cgaagggatt tatagataga agaggtttta gtgatttcgg 200580 gaagtttagt tttacgtgtt ttatatattt aagagtaaaa tttggttttg gtttgtgggt 200640 gtgtagttcg tgggcgttgg ttaggtatat aagacggtcg tttgggttag tttaggggga 200700 ggtagatgtg gtgtaggggt tttttttttt tatgagttta ggaatagttt tgtatttagg 200760 tattcgtttt gtatttagta tttttttttt ttttaggatt gttggttcgt tttatgggat 200820 tgaatatata attttatggg gatcgacgtt ggttttattt ttttttttta taagattatt 200880 tatggggatg tgggaggcgg ggatatacgt tggttttatt ttcgtttttt ataagattat 200940 tttttttgtg ttttggttcg tggatcggtt tttaaggttt ttgagtggta gtaggcggta 201000 tagtttattt gagtagaggt gaaggagagg gttaggttta tttgggtggt tcgaggtagt 201060 gtggagggtt aggagaggag agtatttttt atttttgttt gagtagtttt ttagggtacg 201120 gagataggag tttagggtta gttttgtttt ggagcgtagg gggtttttag tttggtatag 201180 tttttagaag aggagatgaa aaagtttggt tttgggagtt tggggatgga gttttgttgg 201240 ggaggtagcg tggttgtagg atggtagttt tttagaggat attacggtta gggatattta 201300 ttcgggggaa tttttagggg tcgtttgggt aagtcgttta gtttttttga gttttagtgt 201360 tttagttttt ttatttaagg atgggtgtga taattatttg gtaggcgttt gtgtgtgagt 201420 ttttgtttcg ttttaatttt tttgttgttt tttttttagt tattgaggcg gtttttagtt 201480 gcgttggcga tatggtcgat atttttagag atgtcgggtt taagtaggcg tttgtattac 201540 ggaacgagaa ggtttcggtg gatttcggtt acgtggggat tgattttatt ttggagtaga 201600 tgcgtcggaa ggttatgaag tagggtttcg agtttaatat tatggtggtc ggtgagtttt 201660 tattttgtat gttatttaat taatgtcgga aattagtttt agtttttagg gcggtttata 201720 agtttttggg tttggttttt ttttttgtaa aatggggtag taattttgat tttaaggacg 201780 gattgttagt gatattgcgt gtgtatgtat gcgtttggga ggagtttata gtttttagcg 201840 gttttttaga ggggtttgtt ttgtatattt agggtttttg agatgatttt ggggagttta 201900 ggtcggtttg gagtaggttt tgatgagtgg tcgttgtttt tgagtaatga cgttagtttg 201960 tgtagagggt tttgtggtag ttgttttttt attgttgttt tagtttggtt ttttaggttt 202020 tttatcgtat tttatcgtat ttcggttaga ggttttttag tagtttagtt ttagttttgt 202080 tttggaattg gggtttcgtg gtttttatat tttttggtgg tttcggagag ttggaggtta 202140 ttacgggagg tcgtcgatta gtacgatttg ggtagggtga gggggttagg ttggagttta 202200 tagtgggtcg tttgttgttt ttaaagtttt ttaggtttta tttaaatttt atagggattt 202260 tgtgaagggg gcgtttcgtt ttttaggtag aagcgaggtt tagggaaggt tgttaaggtt 202320 ttttagttta tagggtagag aatcgtagtt atcgttttga tttttagaat tgtgttttgt 202380 ttattttacg gggtttaggg aggggtttgg ggaagtgttt tcgttaggtt atattttaaa 202440 taaaggtgag tttgcggggt ttttgtaagg tgtttgggta ttttttaggt cgggtttgtt 202500 tttttgattt ttgttagtcg tgtacgtttt ttttgtttag ttttgtggac gtaaatttat 202560 atttgttagt tcgatatttt tttttttttt tttgtattga tttgggtttt ggtttttttg 202620 gggttttggt gttttttttg ttttttgtag ttttatggga ttcggttgtt tatggttttg 202680 ttgtgtttat agttgtttgg aagttggtag tttgttttaa gggagggcgg aggtgtgggg 202740 ttttttttta cggtttttat tttgttttgt ttgttgtggg ggacgtgttt gtattttgag 202800 gatttagggt tgtttttcgg gaagatggtt ggagagaaag agaggggaga ggtttaaagg 202860 tagtggttag gttgggattt atttttgtgg gttacggagg ggttgttttg ttttttagtt 202920 agggataggg tgagaaggat ttgggaattt ttgcgtttta gttatggtat aggttttttt 202980 tcggagtttt ggttttaagg agagggagag gtagtttagt agttttcgtt tttcgtggtt 203040 gttattgtga tagttttgtt ttttgggaat ggtgcgtagg aggttatttt atttgtttgg 203100 gttttttcgt ttttttaatt ttgagaagaa tagtggtttt gattttttat aaaattattt 203160 ttttttaggg atgtcgagtg aggaataaga cgtggggtag ttttgttttt tttttttttt 203220 ttttttatgg tagttgtgtt tatttgtaga ggtgtaggta aggtggaggg gtatttgttt 203280 ggaggtttat agatttcggg gagaatttta gttttgtttt aatttagcgg ggtgaggttt 203340 gtgtgttttt ttttgggttt tttttttgtg agttttagtt ttttcgttta taaaatggga 203400 ttattttata aagtgagatt aagcgagtta ggtttcgggt agggttttta ataggttgtg 203460 gttgttcgag aatttgtagt agtggtgatg gtggttgtgg tgatgaggat gatgggggtg 203520 gtaatgacgg tgatgatgat ggggtgatgg tgttagtgga gatgatgggg atgatggtga 203580 tggtggtggt gatagtggtg ggatggtagt ggtgatgtgg gtgatggtga ttgtgatggt 203640 ggtggtggtg gtgatggagg tgatggtgat agtgattatg agggtgatgg ggatggtggt 203700 ggtggtgatg gtgatagtgg tgggatggta gtgatgatgt gggtgatggt gatggtggtg 203760 atggtggtgg tggtgattgt ggtggtggtg gtgatgatgg tggtgatgat ggtgattgtg 203820 gtgatggtga tggtggtaat tgtgatggtg gtggtggtga tggtggtgat gatggtgatt 203880 gtggtgatgg tggttatgat ggtggtaatt gtgatggtgg tggtgatggt ggtgatgggg 203940 atgatgatgg tgattgtgat gggggtggtg gtggtgattg tgatggtggt gatgtgggtg 204000 gtggtggtga ttgtgatggt ggtgatgtgg gtggtggtgg tgattgtgat ggtggtggtg 204060 gtggttgtga tggtggtgat gtgggtggtg gtggtgattg tgatggtggt gatgtgggtg 204120 gtggtggtga ttgtgatggt ggtggcgatg gtggttgtga tggtggtgat gtgggtggtg 204180 gtgattgtga tggttgtgat tgtgatggtg gtggtggtga tggtgatgat ggtggtgatt 204240 gtgatggtgg tgatgggagt gatgttggtg attgtggtgg tgaagggggt gatggtggtg 204300 attgtgatgg tggtgaaggg ggtgatggtg gtgattgtga tggtggtgaa gggggtgatg 204360 gtggtgattg tggtggtggt aatggtgatg gtggtaaagg ggtgatggtg gtgattgtgg 204420 tgatgtgggt ggtggtggtg atgtgggtgg tggtggtgat tgtgatgggg gtgatgatgg 204480 taatgtgggt gatggtgatt gtggtggtgg tggtgatggt gatgattgtg atggtggtga 204540 agggggtgat ggtggtgatt gtgatggtgg tgattgtgat ggtgatgtgg gtgatggtgg 204600 tgttgatggg ggtgatgatg ttagtagtgg tggtgatagt gatggggatg atggtggtgt 204660 tgatggtgat agtggtggga tggtagtggt gatgtggttg atgatggtgt tggtgttgat 204720 gattgtgatg atagtggtgg tggtgatgag ggtgacggaa gtggtgatga tggcgggagt 204780 gatgggatga tggtaatagt agtgatggta ttgtgatgat ggtgttgatg gggatggtgg 204840 tgatgataag ggtgatgatg atggtgatga taataataaa agtaataata ataaagggat 204900 atattttgta gtattttagt tggtattttt tagatttaag gtgtcgtggt tggaatattg 204960 atataatttt tgatttgagg ttggttagga tatagatttg gtggatagag agagatggac 205020 gaggagtgtt cgtttttggg ttattaaata gtttaggtta gggattttta gtattagttt 205080 ttgttttttt aggagtttat atttttttta gaaaggtgtt attaaagtta gaatattagt 205140 gtaatttagg gtgttttttg tgttgtgttt ttttgagata gggttttatt gttgtttagg 205200 ttggagtgta gtggtatggt tttgatttat tgtagttttt atattttggg tttaagtgat 205260 tttcgtgttt taggtatgtg ttattatatt tggttaattt ttgtgttttt tggtagagat 205320 agggttttat tatgttggtt aagttggttt cgaatttttg attttaagta atttattttt 205380 tttagttttt taaagtgttg ggattatagg cgtgagttat ttcgtttggt cgatttttgt 205440 ttttttaaaa gatagggttt ttgttatttt ggagtggtaa tgattttagt ttattgtagt 205500 ttcgtatttt tgggtttgag taattttttt attttagttt tttgcgtagt tgggattata 205560 ggtgttcgtt attatattta gttaatgttt atattttgat gtagagatag ggtttttttg 205620 tgttgtttag gttggttttg aatttttggg tttaagtaat ttttttgttt tagtttttta 205680 aagtgttggg attataggta tgagttatta tatttggttt agggtatttt ttttggtgtg 205740 ttgttagcgt agtttaaggt agttttgtgt agggtaaagt aatggggttt cgagtttgga 205800 ggggtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgcg cgtacgcgcg cgcgtgttat 205860 atgtgatttg tttgtgtgtg ttgtgagagt tgtgtgtgag gtatgtgtaa gaggtatgtt 205920 tgaggtgagt tgtgtgtgtg ttgtgagttg tgtatgtgaa gtgtgtgtgt tgtgaggtgt 205980 gtgtatgagg tgtatgtgag ttgtgtgtgt tgtgttgtat atgaatgtta tttttttatt 206040 ttcgtttgtt ttagttattt gtggattggt tgtttgtata tacggttatt gtttttcgag 206100 tggtattatt ttgtaggtta gcgtttttta gtatatggtt ttatagattt tatgggatat 206160 gcgtgagttt gtttgatgtt tatattagtt ttacggggga aggattgttt attttatttt 206220 gtagattagg aaattgagat acggtgaggt taggtgattt gtttaggttt tggtcggtta 206280 gggaggagta gtttgaatat ttgggttttg gttgtaatta ttttggtgaa ttgtaggaat 206340 ttcggttatt tggtgtattt tgggtagttt tgggtttttt cgttagttcg gtttttgttt 206400 tgtttaaaat ttgagttatt aggagatttt ttgtttagaa agtataaggg gtataagaga 206460 tgtcgatttt tttaggttcg gtttattttt taggagagga ttgtggtttg ggttgtgttg 206520 gtattagagt tcggttgtgt gggtttatat agttattgga tattcggttc gagggtgaag 206580 ttttcggggg ttgtttggta gggatattgt cgggaggtag tttaggtatt gttgaatttt 206640 agattggaga gtttcgtgtt tgggtgggag gggttttatg tgtagatttt gttggttttt 206700 tcggagagat ttttgatcgg ttttttattt tttttttagg gtagagcggt ttgggtaaat 206760 ttattttaat taatattttt tttaaattta aaattagtcg gaagtcggtg tagtttattt 206820 tagaggagcg tatttttaag attatcgaga ttaagtttat tacgtacggt tagtggtcgg 206880 gagtgggttg ggggtgtagg acgtttttgt ttttttggag tataggggtt gggggttaag 206940 attattatat atagttagtg gttaggggcg ggttgggggt gtaggatttt tttgtttttt 207000 tggagtatag agtggggggt taagattatt atatatagtt agtggtcggg agtgggttgg 207060 ggatgtagga cgtttttgtt tttttggagt ataggggttg ggggttaaga ttattatata 207120 cggttagtgg ttggggatgg gttggggatg tgggatattt atgttttttt ggagtattgg 207180 tgcggtgtga gggtgttcga gttaggtaat tttaggtttt taagacgggg attcgttgtg 207240 tttattattt ttagtatgtt gagtatgttg gggttttggt tgtgatgggt tagtgtttcg 207300 gatttttgtg ggtttcgtta tattgagttt tttatagata attgagtttt ttattaaaag 207360 tttgataggt aaggggtttt taggggaatc gttatcggtt tgtgtcggag ttggttgagg 207420 aaggttatta atttttcggt gtttttttgg ttgttatcgt tgtttatttg gggttgtttc 207480 ggggttagtt aggtgtgggg tgtttgtgag ggtttttcgt tttttttttg attttgcgtt 207540 cgtggttttg tgtagatatt gaggagaaag gcgttcggat gaagttgata gtgattgata 207600 tattagggtt cggggattat attaataacg agaattggtg aggttttttt agggggagga 207660 gtattagcgg gggttttagg gttttttgga ttttatttag agttagtttt agaggttttt 207720 cggttcgcgg gggtgtaggg tttatttttt gggatttgat atgttgttaa agtcgtacgt 207780 tttaggggtt tgaaaatttt ggattaaagt agaattattt ggggaatttt gttgttttta 207840 atttattatt tgaggttagt tcggggaggt tggtttggga ggtcgagggt aaggttgtgg 207900 tattttcgtt tagtaagtta gattttttag ggtatgtatt ttattggaag gtggggtgtt 207960 gggttttgag ttttgggaat gtacgatttg tttggggagg gtattttatg tgtttgttga 208020 ttcgttttta ttttttacgt agttggtagt ttattatgaa gtttattaat gattagtacg 208080 agaaatattt gtaggaggag gttaatatta atcgtaagaa gcgtatttcg gatattcgcg 208140 tttattgttg tttttatttt attttcgtta tcggttattc gtacgttttt gtagtgtcgg 208200 cgtttttatg tcgggtgttt tgggtttttt ttgttttttg ggattgtaag acggtgttgt 208260 ttgttttgtt gttgggtgta gaggggttga gttaggggtt atggtcgtta gttatgaagt 208320 tgggggtgtg ttatgtttgt atttttaaag ttttatattg atttttatgt aagtgttttg 208380 tttagttttt attttttagt tgcgttttgg ggagttgagg gttaggtagg ttttgggttg 208440 ttttggagtt tggtggtttg tgttttgttt ttttaggtta ggttttggta ggtggagtgg 208500 gagtttttag ttaagtattc gtagcggtga ttgatttttt tattcgggtt ttgttttatg 208560 ggatttttta gagggtttgg tgcgttttta gacgggaagt atagagatta gtgttggttt 208620 tttttagggt tggacggggt tgttgttggt gttggtgaga gttttttttt ttcgtcggtt 208680 ttgttcgtat ttgacgtcgt ttttagagat tagtaagggc gggaggttgt atgtattttg 208740 gtaggtggat tttttatggt tttacggatt ttttgttttt agttttttgt gtattttttg 208800 ttagatattt gtggtttatt ttgagttagg gttgggagga ggaggattag aggttagtag 208860 gagtggttgg tggaggtagt cgtgggtggt ttgtttgtat gggtgggtgg agaaggtttt 208920 tcgtatttgt tgttttagat gtattttttt gggcggagga agtttagggg tttggggaaa 208980 ttatattttg tgggtattag gtgtaggaag gagtttggtt ggtgggtagc gggttttatt 209040 tagagtttgt gggaaaattt aagtcggagt tttcgagttt attttttggt attatttttt 209100 gtgggttagt aggagttagg ggtagggggt tagttcgttg tttatgggtt ttttttgaat 209160 tgaatatttg tttttttagg tagaacggtt tatttgcggt tttgtggtag ttgttttagt 209220 tgttttaagt tttgttttag ttgaggttga tggtaggagg tagaagtttt ttttgatgtt 209280 agttgggtaa gtcgagggcg ggcgggcggt ttgtggtatt tttgttattt tttagtattg 209340 attttttggt tgggatttta gttaggtatg ttgtttggtt tcgtttaagg cgtttagttt 209400 tatggggtag gggcgggttt tggttatttt tgtttaaatt tttgttcgga gcgggttttt 209460 ttttagttat gtgtgtgatc gatttatttt tattgtggga aaagttcggt tttagaattg 209520 gggaagatgg tgttttagtt ttagggtttt gttagttttt gttatttata gtttttttta 209580 tattagattt taggtttatt ggggttaagt aggtaagggg agtagttcgt ttggtgtagg 209640 ggagtagttc gtttggtgta ggggtatcgt atattggtgt tagtttttat tttttttgtt 209700 tttttttttt tagttaaagt tttatagtaa gacggttgtt gagttaacga tagttttttt 209760 gtgtggatat gtaggggtgt ggttgggatt ttagaattta tggacgaggg tgtttggagt 209820 tggttttggt tcgtttggtt tgtgtagtgg tgttatttgt gtttgggata tattcgtgtt 209880 ttttttttgt tttatattta tagcgtggtc gattcggttc ggggttttgt ttttgttagt 209940 agggattttc gtgagtttcg agttagtatt tgagagtgtc gatatttgtt tgggggtggg 210000 tgttttttta ttgtttcgtt tttttagatg agttttacgt atattttttt gttttagttt 210060 taggtttttg gatatcgagt ttatgaaacg tttgagtaag gtggttaata tcgtttttgt 210120 tatcgttaag gcggatatat ttattttgga ggagagggtt tattttaaat agcgggtagg 210180 gttttatttt tatttgtttt agtttttttg tgtaatttgg agacgttgta ggtttggtag 210240 gggttatttc gtttaaagga gttatattgt tagggagatc gaatcgttgg ttattttttt 210300 tagcgggtgg ttggtttggt ggtttttggt ttaggtggtt gttgggggtc gtttttgaga 210360 tggttttttt agttttttta tattttaaaa gtagttttgt gggagtgtta attttttagt 210420 agagtttttg aggggggttt tggagaagat ttggattagg tagatggtga attttttttt 210480 tagggagtga ggtcgagtag gggtcgtgcg atatggttta ttttgtttta tgtttttttt 210540 tttttttttt gagaaagggt ttggtttagt tgttaaggtt gtaatgtagt ggtataatta 210600 tggtttattg tagtttttat tttttaggtt tagttttcga gtagttggaa ttatagacgt 210660 atattattat gtttggttaa tttttgtatt tttagtagag acgaggtttt gttatgttgt 210720 ttaggttggt ttttaatttt tgggtttaag ggattttttt gttttagttt tttaaagtgt 210780 tggggttata ggtatgagtt attttatttc gttttgtttg gtttttatta gatggaagag 210840 aagttgggtt aggtgtggtg gtttacgttt gtaattttag tattttggga ggtcgaggcg 210900 ggtagattat ttgaggttag gagtttgagg ttaatatgat gaaattttat ttttattaaa 210960 aatataaaaa tattagtcgg gtatggtggc gggcgtttgt agttttagtt atttgggagg 211020 ttgaggtagg agaatttttt gaattcggga ggcggaggtt ttagtgagtc gagattgagt 211080 tattgtattt tagtttgggt gatagagcga gattttattt taaaaaaaaa aaaaaaaaaa 211140 aaagttttag gagggatggt ttttgttatt ttttttttcg ttatcgtttg aggtttttgt 211200 tgtgggatag ggaggggtat ttaagtaaga gggtagtttt gggttttttt ttttgatagg 211260 gtagtatatt agagttatat ggggtgtttt ttaaaatgaa atcgaggtgt ttgggttgcg 211320 gtattatatt tgtttcggtg ggtgtgggtg gggtttgtaa tttatttcgt tttggggtta 211380 ggtgttaggg atttttttag tatgtgtagg ggaagatagt ttatataaag tgggtgtgtt 211440 tgtcggaggt tatatacggg ttgtggtttg tgtttgggta ggcgagtagt cgtttattgg 211500 gatgtttttg ttgtacgtat ttatgtcggg ttgttggtag ggagttgaga ggttattgta 211560 ggcggggttt ttgttggaat tggggattgt gacgagggtt ttttaggaag ggttttagga 211620 ggggaggttt cggtaatttt gagtattttt ttggggttgt gatgagtagg agaagagagg 211680 tgggaggtgt ttaggacgat gattttaagt ttttggggag ttgtagcgtc gtttaggata 211740 gtaggtgtat ttgtagttgt tttttttttt tttaggaggt ataggagttg gaggtgattg 211800 gtgttatagt tttttagagt ttgtttttga attcgagttt ggggtagtat atagtgtgga 211860 ggttatgtgg taaatattag tgggtgggta gagtttgtta tagggatggg tttatttttt 211920 ttttttttta ttttagatta tcgtagattt gttgtttaac ggtatcgacg tgtattttta 211980 gaaggaattt gatgaggatt cggaggatcg gttggtgaac gagaagtttc gggtgagtgg 212040 atttattagg atgttgtttt taggggattt ttagtttttg ttgaagggtg ggttgggggt 212100 ttggaggatt ttaagttatg aaattatatt tttggggtta gagggtattg agtttaggtg 212160 tttgtattta gtgttgttag gttgaggttt tcgtttttgg gggattttag gtttagggta 212220 gtttttttcg ggggtttagg ggagggaatt gttttttcgt atatgtgtaa ttaatatcgt 212280 ttgttcgttt tttaggagat gattttattt gttgtggtgg gtagtgatta cgagtattag 212340 gttaacggta agaggatttt tgggaggaag attaagtggg gtattatcga aggtattcgt 212400 cgtaggcgtc ggggttttag atagatggga agatagtttt ttttgttgat ttagagtttg 212460 tgggttacgt ttgagttagg gattcgtgga attttattta ttgttttgtt ttatttagag 212520 ggaggggttt ttttgttttt atttaatttt tgggaaagtg agagggtaag tggtttgtgt 212580 agatgttttt attttagatt ttttttcggg tagggaaaga tttagggaga taggagttgg 212640 gatgggggtc gttaagtttt ggattttggt gtaggttttt ttataggtat ttgtgtggtt 212700 ttggataaat cgtttaattt ttttgggttt agaaaagggg tgggttgtag ttttgtgagt 212760 tagatggatt ttcggttttt tattttgttg aagtttttgg gatttttata ttttagtttt 212820 ttgagtggtt gttgtaatta attagtataa acgaggggat ttaaaataat ataaacgtat 212880 ttttatagtt ttagaggtta gaggttcgaa attaggggtt gttttttttt gaggttttga 212940 ggattagttt tatttatgtt tttttttttt tggtggcgtt tggtattttt agttgtattg 213000 taaaggtatt atatgtttta atttttgttt tattgttata gggttttttt ttttgtgttt 213060 ttgtttcgtt tttttttttt tttttttttt tttttttttt ttgtttgaga cggagtttcg 213120 ttttgttatt taggttggag tgtagtgttg taattttagt ttattgtaat ttttgttttt 213180 tgggtttaag taattttttt gttttagttt ttcgagtatt tgggattata gttacgtatt 213240 atttatttga tttaattttt gtatttttag tagagatagg atttcgttat gttggttagg 213300 ttggttttaa atttttgatt ttaggtgatt tgtttatttt gtttggtttt ttaaagtgtt 213360 gggattatag gaatgagtta tcgagtttgt tttttttttt ttttgttttt ggataaggat 213420 gtttgttttt ggatttaggg tttattttaa gtggatgatt ttatttggag atttttaatg 213480 aatttataaa gaaagacgtt ttttaagtaa ggttataatt atgggtttta aggtttggat 213540 tttgattatg tttttgaatg gatgggagtt tttggggggt tatagtttaa tttatttttg 213600 gcggtgatat ttcgggaggg atgggttcga acgttttttt tttttttttt tttttgtttt 213660 tttatttttt attagaatgg aagaggggaa ggtgtagagg gaaatgtagt aggaaaagtt 213720 attttgtttt gggagagtat ttggttgaaa ggtttagtag agtaggaagt ataagttttt 213780 taatttttta gggttttagt ttttattatt tataaagtgg gtgtagtgtg ttaagatttt 213840 agtgagttga gagattgttt taaagattat agagtttttt gggaagttgt tgttttaaaa 213900 aaatggttat aatgataatt attaggaggt attagatatt tttgtgttat tggttagata 213960 tgggttattt cgttttatgt tcgaagtttt tcgtatttat tttttttgta gagttgaaga 214020 ggtgttgtga gtagaaaatt tgttaaggga tttagaacgg gaggcggttt tagaatttat 214080 agttttagtt ttgtattaga ttttttcgag atgggagttt atgtttggag gagggtgtgg 214140 agaggtatac gggttttttt tttgtttgta tttttttttt attattattt ttgtcgggtt 214200 tattttgcgg gagttgttta gttgggtgta gtttgggtgt tttttagtat tcgtttgtgg 214260 tgttaggttg gtttgttttt ttttggtttt tttgtttgta gttttttttt ttttttttgt 214320 ttaaagagtt tttgttgttt aggaaatttt ttatgaaagg taggtttggg agagttaggg 214380 atggatgggt ttgggacggg tcggcggttt tgttatgggc gtgtttttgt tgtattttgg 214440 tggttaattt tgagtatcgt aggtggtcgg tgatagaaat tgttaggaaa tgtataagag 214500 agaggttttc gtattttttt gatttgtgcg ttgttgagta ttattggttt tagttgagga 214560 agagtttgga atttgttagg atagttgtga ggtggtgggg tttatttttt agtagtttta 214620 tatgaggatt ttggaaatgt gtttttagta ttgttgggtt tttatattag gggttttatg 214680 agtttatagt tgatttgata ttcggattag taagggttgt gttttgtttt tgttttttat 214740 ttggtgaata gtattttgag gtattttttt tatttttaga aattatttta agtattgtta 214800 atagaaatgt ggggtgtaat tgattacgtt atgaatttat ttaattttta tgtttttgag 214860 aggcgggtga cgttattatt tatattttat ggatgaggaa attgagggaa tgagagtaat 214920 ttgttcgagt tagggagtgg cgattatata ttttaatttt agtttgagag ttttattttt 214980 tttgtcggtt ttcgttgttc gttagtgtta gatgagagtg ttgttggtta gtttgtagga 215040 ggttttagtg tggatatcgt tttatatagg gtcgtggtag gagggtttag gtaaaggtaa 215100 tcggtatagt attgagagta tttgagggtt gggtaaggtg gaggtttcgg ttttgtttgt 215160 tggtttatta agtaaaaatt agatattttt aatttgggga aaagttatgt ggttttgcga 215220 tggggtagtt tggagttagg tgtatgggtt ttgtatttcg ttttagtttt atgtattgtg 215280 gagttgagat agatatagtt tttgcgtttt ttatgtttta tttttttttt tttttttttt 215340 tttttttttt tttttttttt ttgagacgaa gttttatttt tttgtttagg ttggagtgtc 215400 gtggcgtgat tttggtttat tataattttt attttttggg ttttagtgat ttttttgttt 215460 tagttttttg agtagttggg attataggcg tttggtatta ggtttggtta atttttgtat 215520 ttttaataga gacgagattt tattatgttg gttaggttgg tttcgaattt ttgatttcgt 215580 gatttattta ttttagtttt ttaaagtgtt gggattgtag acgtgagtcg tggtgtttag 215640 cgtttacgtt ttattttcgt aagataatgg ggataataaa ggaattataa gagatatttg 215700 taggtgtgtg aagacgaagt ttattatatg ggagggtatc gggtgttttt atttgttttt 215760 tttgttcggt tttttatttt tagtgatgtc gtttattgtt ttttttgtta aaaggttttt 215820 tgttatataa tagttatata tgttaggtat cgcgtgttta tataggagtt acgaagtata 215880 gtaataaaat gattattttg agatggttat tagttcgagt tcgagggtat ttgtgggtgt 215940 tcgtggtttt ttgtttagtt tttttgagaa gtggttattg tttcgagttt gggtttgtat 216000 gtattgtgtg aagtgtatat gtttttgagt aatgtttagt attgttgatt tttgagtttg 216060 tgaatggtcg tttatagtac gtagtttttg tgtgtgtttt tgtgtgtgtg tgttttgagc 216120 gtatataagg tggatggggt cgtgggggta atattttgtg ggttataggt tttttttaaa 216180 attttagttt cgatttttgt tttattttat ttttagtagt ttagtttttt gtttgttttt 216240 aggtttttgt tgggacgttt tgtttttttt ggttatttta gtggtgcggg ggtttattgt 216300 tttggttttt ttattgtggt ttttttttat gtttttattt ggtttggtta ttgtgttatt 216360 ttttattagt taggaatttt ttggagagta ggagttgagt tgtttaggag taggagttgg 216420 tgttggttat tttagtattt tttagattga gggtagtgtt aggtgtttta tatttagttg 216480 tagagtaggt ggtttttttg tttttttgtt tatggggttg tttttagatt ttgtttttgg 216540 tattagtatt tttgggtagg gggagagagg tggggttcgg gtagagtttt tttattggga 216600 tattaaagtt ttttttgttt ttttttttag ttgaaaatat tatatattgt gagtttgttt 216660 atttgcggga tttttttatt aggtgagaga tagggtgttt gggtggggtt gacggtttta 216720 tttttaagag ggttttatag cgggtggggg tagtgggtgt ggggtcgaag ttttgggtag 216780 agtgggtgtt ttttgttatt tgtttgtttt gttttcggga agattttgga agtttatttt 216840 ttgaaaaaga aaatttattg ggaaatgaag taggtagtga agattttttt taatttttgc 216900 gaagttggtt ggatgggaag gttgagtttt gatttattgt ggtttggttc gttagagttg 216960 ttcggtggtt attaagggtt tagtgaggtt ttatgtgtag gttttgtcgg tagcgtgggg 217020 cgtttttagt ttcgatttta ttggtttttg atttttattt tttttatttg gttgaggttt 217080 ttttttgttt tttttgagtt taggtaagga ggggaagttt tgatggagag ggtgttgggt 217140 gggtggtttt tggagtgtgg gttttggttt gggtaggttt ttttttagta agtagttggt 217200 atggatgatg ggaatgttat taagaggagg ggtttttagg ttggcggggg taggggtggg 217260 gggatttcgg gagtcgtttt gttattgtgg ggatattggg ttttttaatt tttttttaga 217320 ttattttttt tgagttgtag aggaatgaaa attcgagttt aggatttttt ttttttgggg 217380 ataagggtaa tttagttttt tgttttaggt tatttgtttg ttataggtta tagttttgga 217440 ggtcggtggt tatttattgt ttttattttg ttagtatttt ggatatcggt ttggagtaat 217500 aatgttttag ttttgttttt ttgagtttat gtattgtttt tgggttttgg atttagggtt 217560 atagggtgga tttagaggga gatatatgta ttggaatatg tgtgttttga tcgagtttgg 217620 gtttattagg gggattgatt ttttttttaa aacgtgtatt agatttggtt taatatggtg 217680 ggtttggggg attttatggg gagttaagta gtcgggatgg ggagtggggg tgggggtagg 217740 cgggtttgag ttcgaggtag gtcgagtagg gtttttgttt cgttgttttt atttcgttgc 217800 gtttatttta ttgattcgtt cgttttttat ttttatagga cgtatatgta gaatattaag 217860 gatattatta gtagtattta tttcgaggcg tatcgtgtga agcgttttaa cgagggtagt 217920 agcgttatgg ttaacggtat ggaggagaag gagttagaag tttcggagat gtagacgtta 217980 ttttgtttat tttcgggatt ttgtttttaa gttattttcg ttttttttta ggttttttta 218040 ttattttatt ttattttata tgattttttt tatttgttat cgttttttat tttttcgata 218100 tgttgttagg aaataaggga aggggttttt tttcgagtga gttagtgatg aggtcgcggt 218160 tttttcgagg ttgtggggag gttgtattgg agttataggt aggggtgaga gtatttattg 218220 aattgatatg attttttgtt tttaggtttg gtttttcgag ggtttagaag agtagtttcg 218280 gtgtgtagat tattcgtttg tgtggggttt ttagtgtcgg aggttttggg gtgggggtta 218340 ggtttcgtat ttgtagagga gtttagtggg ttgtacgttt ttttttattt ttatcggttt 218400 tgttttttgg agtgtgttag agtttagggg agaatgtagt ttattaggag tatttggatt 218460 ttttgttcgt tatatggtgt ggttattatt tagtttttat ttttgttttg tttttaaggg 218520 tagaaaattt tagggttttt tgttatcgat tgtttagtta ttttaagttt tttggtagtt 218580 gttttttttg gagtagaaag tgtttttatt ttagttattc gtagattgtt tggttagatg 218640 cggggatagg ttggaatgag ggaggcgttt ttattttttt gttatttttt ttttacgtta 218700 ttttcgtttt tatcgggttg taggtgttgt tgatgcgttg ggatttgatt gaggataaaa 218760 aggaaggaga gatgattttt atttttttat tttttagttt tgaaaaggtt taagtaagtg 218820 agtttggtgg aggagttgag ggagggagtt atggaaggtg ttagaaggaa ggttggcggg 218880 ggtacgtgtg ggtcgtggtt tgggttggtt agagtggcgt gagttgttcg gcgtttgttt 218940 tgtttaagtg attagggaag tgtgtgtgtg tttatgtgta tgcgtgttcg tttgtttgtt 219000 tagtgtttgg gtttggttta agattgggtt gtagttatat taatgtttag ttagttattt 219060 ttgttattta ttttttttgg tttaggtttt gttgattttt tgagttgggg aggtgggagg 219120 ttaggcgagt ttgattttgt tgatttattc gtgtttgggt tttttttttt agagtttatg 219180 gtaacgaatt tttagaaagg agagaacggg cgttaggggt gtatagttta tagttgaaga 219240 gtaaggtttc gtggtagtac ggttcggttt tttatttttt gtttttacga ggggatttat 219300 gggggttgtt tttgtagggt atagatgatt aaagtttttt tttgtttttt gttatttgtt 219360 ttgtttttgg ggagaaagag gggtttgatg agattttatt taggtgtata tattattagg 219420 tgtatttgta ggtatcgggt tggttgtttg tagttaggag aaggttagcg agaaggagtg 219480 tatgagtgtg agtgtgtgtg tatggaagtt ggggtattgg gcgtttgatt ttttttttat 219540 ttaagagagg aaggattttt tattattttt attggtgaga tagtttattt tgttaatttg 219600 ttatgttttt gttaaaatta agattttgaa ggaaatgagt ggttagcgtt agggtttagg 219660 ttatgtggtt tgtttagttt taatgttatt tggtggcggg gtggggtggg ggtgggtagt 219720 agtattttag ttttgagatg ttttattttt tttttttgta attagatttt gaaaaattgt 219780 tcgttttatt aggttttgtt ttttaatggt tttttgttac gtgtttttcg agaaatttgt 219840 ttttttgtat aaatgataaa gtgttgaaaa tgtatttttt gaaataaatg ttttaaatgt 219900 agaaattta 219909 <210> 5 <211> 219909 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 5 tgggtttttg tatttgaaat atttatttta ggaaatatat ttttaatatt ttgttattta 60 tataaaaaga taaatttttc gggaggtacg tagtaaaagg ttattgagga atagagtttg 120 atgaaacgaa taatttttta aagtttggtt atagagaagg aaagtgaagt attttaaggt 180 tgggatgttg ttgtttattt ttattttatt tcgttattaa gtgatattga ggttgggtag 240 gttatatggt ttgggttttg gcgttggtta tttatttttt ttaaaatttt ggttttggta 300 aaaatatggt aagttggtaa agtaaattgt tttattagtg ggggtggtga ggggtttttt 360 tttttttggg tggggaggga gttagacgtt tagtgtttta atttttatgt atatatattt 420 atatttatat attttttttc gttgattttt ttttggttgt aagtagttag ttcggtgttt 480 gtagatgtat ttggtgatgt gtgtatttga gtggagtttt attaggtttt tttttttttt 540 taggagtaag ataggtaata ggaagtagga agggattttg gttatttgtg ttttgtaaag 600 atagttttta tgggtttttt cgtggggata gagggtgagg ggtcgggtcg tgttgttacg 660 aaattttgtt ttttagttgt ggattgtgta tttttgacgt tcgttttttt ttttttaggg 720 gttcgttatt atgggttttg aggggagggg tttaggtacg ggtagattaa tagagttagg 780 ttcgtttggt tttttatttt tttagtttag agagttagta aggtttgggt taggaagggt 840 gagtggtagg ggtggttggt tgggtattaa tgtaattata gtttagtttt gggttaaatt 900 tagatattag atagatagac ggatacgtat atatatggat atatatatat ttttttggtt 960 atttgggtag ggtaggcgtc gggtagttta cgttattttg attagtttaa gttacggttt 1020 atacgtgttt tcgttaattt tttttttggt attttttatg gttttttttt ttagtttttt 1080 tattagattt atttgtttag atttttttaa aattggggga tgagggggta ggggttattt 1140 tttttttttt tttattttta attagatttt agcgtattag tagtatttgt agttcggtgg 1200 gggcgggggt ggcgtgagag ggggatggta gggagatgaa gacgtttttt ttattttagt 1260 ttgttttcgt atttggttaa gtagtttgcg gatggttgag ataaaggtat tttttgtttt 1320 aggaggggta gttgttaggg ggtttggagt ggttgggtag tcggtggtag gggattttgg 1380 agttttttat ttttaggagt agggtagggg taggggttga gtgatggtta tattatgtgg 1440 cgggtagggg gtttaggtgt ttttggtggg ttgtattttt ttttgggttt tgatatattt 1500 taggggatag ggtcgatggg gatggagggg agcgtgtagt ttattgggtt tttttgtaag 1560 tgcgaggttt ggtttttatt ttaaggtttt cggtattgag aattttatat agacggatga 1620 tttgtatatc gaagttgttt ttttgagttt tcggggagtt aggtttgggg atagagggtt 1680 atgttaattt agtgggtgtt tttatttttg tttgtggttt tagtgtagtt tttttataat 1740 ttcggggagg tcgcggtttt attattgatt tattcggagg gaggtttttt tttttgtttt 1800 ttggtagtat gtcgaagggg tggggaacga tgataaatgg agaaaattat ataaaataaa 1860 atggggtggt gggagggttt ggggggggac ggaaatgatt tgggggtagg atttcggggg 1920 tgggtagggt ggcgtttata ttttcggggt ttttggtttt ttttttttta tgtcgttggt 1980 tatggcgttg ttgttttcgt tgaggcgttt tatacggtac gtttcgaagt ggatgttgtt 2040 ggtgatgttt ttgatgtttt gtatgtgcgt tttgtggggg tggggggcgg gcgggttagt 2100 gaggtgggcg tagcggggtg ggggtagcgg ggtaggggtt ttgttcggtt tgtttcggat 2160 ttaggttcgt ttgtttttat ttttattttt tatttcgatt gtttggtttt ttatggggtt 2220 ttttaggttt attatgttgg attagatttg gtatacgttt tgggggaagg gttagttttt 2280 ttggtaagtt tagattcggt tagaatatat atattttagt gtatgtgttt ttttttgggt 2340 ttattttatg gttttgggtt tagggtttag ggatagtgta tagatttaga gggatagggt 2400 tggagtattg ttgttttagg tcggtgttta gggtgttggt agggtggaag tagtgggtga 2460 ttatcggttt ttaggattat ggtttgtggt aggtaggtgg tttggggtaa agggttgggt 2520 tgtttttgtt tttaggaaaa aaaagttttg ggttcggatt tttatttttt tgtagtttag 2580 gaggaataat ttggagggag gttggaaagt ttagtatttt tataatggta gaacggtttt 2640 cggaattttt ttatttttgt tttcgttaat ttggaggttt ttttttttga taatattttt 2700 attatttatg ttagttgttt gttgaggaag aatttgttta ggttagggtt tatattttag 2760 ggattattta tttagtattt tttttattag ggtttttttt ttttgtttgg atttaaggga 2820 aataaggaga agttttagtt aggtgaaagg ggtaggggtt agaggttagt gggatcggag 2880 ttggagacgt tttacgttgt cggtagggtt tgtatatgag gttttattgg gtttttagtg 2940 gttatcgggt agttttaacg ggttagatta tagtggatta aagtttagtt tttttattta 3000 gttaatttcg taggggttga aaaggatttt tattgtttgt tttatttttt agtgggtttt 3060 tttttttaga agatgggttt ttaagatttt ttcgagggta gggtaggtag gtggtagggg 3120 gtatttattt tgtttagggt ttcggtttta tatttattgt ttttattcgt tgtagggttt 3180 ttttaggggt gaagtcgtta gttttattta agtattttgt tttttatttg atgagaaggt 3240 ttcgtaggta ggtaaattta tagtgtgtgg tgtttttaat taggagagga gataggaggg 3300 gttttaatgt tttagtggag aaattttgtt cggattttat tttttttttt ttgtttagaa 3360 atgttggtgt taaaagtaga gtttgagggt agttttatgg gtaggagggt aggggaatta 3420 tttgttttgt agttgagtat aggatatttg gtattgtttt tagtttgggg gatattggag 3480 tgattagtat tagtttttgt ttttggatag tttagttttt gttttttaga aagtttttgg 3540 ttaatgggag atggtatagt gattaggtta aataggagta tggaaggaag ttatagtgga 3600 gaagttaggg tagtgggttt tcgtattatt ggggtgatta gggagagtag gacgttttag 3660 taggggtttg aagataggta gggggttggg ttgttgggaa tgggatgaag taggaatcgg 3720 agttgggatt ttaaagaaaa tttgtggttt atagggtgtt atttttacgg ttttatttat 3780 tttgtgtgcg tttagagtat atatatatag ggatatatat aggggttacg tattgtggac 3840 gattatttat aagtttaaga attagtaatg ttaaatattg tttagggata tgtgtatttt 3900 atataatata tataagttta agttcgggat agtggttatt ttttagggag attgggtagg 3960 agattacggg tatttataag tgttttcggg ttcgagttgg tggttatttt agagtggtta 4020 ttttattgtt gtgtttcgta atttttatat gaatacgcgg tgtttggtat gtgtaattgt 4080 tatataatag aaggtttttt aataaggagg gtagtgaacg gtattattgg aggtggggag 4140 tcgggtaggg aaggtaaata aagatattcg gtgttttttt atgtgatgaa tttcgttttt 4200 atatatttgt aagtgttttt tgtgattttt ttgttatttt tattatttta cgaaaatggg 4260 gcgtagacgt tgggtattac ggtttacgtt tgtaatttta gtattttggg aggttgaggt 4320 gggtggatta cgaggttagg agttcgagat tagtttggtt aatatgatga aatttcgttt 4380 ttgttaaaaa tataaaaatt agttaggttt ggtattaggc gtttgtaatt ttagttattt 4440 aggaggttga ggtaggagaa ttattggaat ttaggaggtg gaggttgtgg tgagttaaga 4500 ttacgttacg gtattttagt ttgggtaaaa gagtgaaatt tcgttttaaa aaaaaaaaaa 4560 aagaaaaaga aaaagaaaag aaaagaaaat gaggtataga gaacgtaaga attgtgtttg 4620 ttttagtttt atagtgtata aggttggagc gggatgtaga atttatatat ttggttttag 4680 gttgttttat cgtagagtta tatggttttt ttttaagtta aaaatgttta gtttttattt 4740 ggtaggttag taggtagggt cggggttttt attttgttta gtttttaagt gtttttagtg 4800 ttatgtcggt tgtttttgtt taggtttttt tgttacggtt ttgtgtaggg cggtgtttat 4860 attagaattt tttgtagatt gattagtagt atttttattt aatattgacg ggtagcgaga 4920 gtcggtagga agaatggggt ttttaggttg gagttggagt gtgtgatcgt tattttttgg 4980 ttcgggtaag ttatttttat ttttttagtt tttttattta taaaatgtgg ataataacgt 5040 tattcgtttt ttagggatat gaggattaaa tgagtttatg gcgtgattaa ttatatttta 5100 tatttttatt gataatattt ggggtggttt ttaaggatgg gaaagatatt ttaagatgtt 5160 gtttattaag tgggaggtaa gaataaggta tagtttttat tagttcgggt gttaggttag 5220 ttatgaattt atggggtttt tgatataaaa atttagtagt gttgaaggta tatttttagg 5280 gtttttatat aagattgttg gaaagtgggt tttattattt tataattgtt ttgataggtt 5340 ttagattttt ttttagttgg agttagtggt gtttaataac gtataggtta gagaggtgcg 5400 gggatttttt ttttgtgtat tttttgatag tttttgttat cggttatttg cggtatttaa 5460 ggttggttat tagggtgtag tagaggtacg tttatagtaa agtcgtcggt tcgttttagg 5520 tttatttatt tttaattttt ttaaatttgt tttttataaa aagtttttta aatagtaaga 5580 attttttggg tagagaggaa gagaggaatt gtaggtagag gggttaaggg gaggtaagtt 5640 agtttgatat tataggcgga tattggaaaa tatttaggtt gtatttagtt gggtagtttt 5700 cgtagggtgg gttcggtagg ggtggtggta ggggaggagt gtagataggg gaaaggttcg 5760 tgtgtttttt tatatttttt tttaggtatg aatttttatt tcgagggagt ttggtgtagg 5820 gttggagttg tagattttag agtcgttttt cgttttgggt tttttggtag gttttttgtt 5880 tatagtattt ttttaatttt gtaaggaggg tgggtgcggg gagtttcgga tatgaaacga 5940 gataatttat gtttagttag tggtatagga gtgtttgatg ttttttggta attgttatta 6000 tgattatttt tttagagtaa tagtttttta aaaagttttg tggtttttgg gatagttttt 6060 taatttatta aaattttggt atattgtatt tattttgtgg atgatgaaaa ttgaggtttt 6120 ggaagattaa gagatttgtg ttttttgttt tattgggttt tttagttaag tgttttttta 6180 gaataaagtg gttttttttg ttgtattttt ttttgtattt tttttttttt tattttaatg 6240 agaaatgaag ggatagagag aggaagggga aggaaacgtt cgggtttatt tttttcgggg 6300 tgttatcgtt aggagtgggt tgaattgtgg ttttttaggg gtttttattt atttaaagat 6360 atggttaagg tttaggtttt ggaatttatg attgtgattt tatttggaaa acgttttttt 6420 ttatagattt attaaggatt tttaaatggg attatttatt tagggtaggt tttaagttta 6480 aagataggta tttttgttta aagataagaa ggaaagaggg taggttcggt ggtttatttt 6540 tgtaatttta gtattttggg aggttaagta aggtgggtag attatttgag gttaggagtt 6600 taagattagt ttggttaata tggcgaaatt ttgtttttat taaaaatata aaaattaagt 6660 taggtgggtg gtacgtgatt gtaattttag atattcggga ggttgaggta ggagaattat 6720 ttgaatttag gaggtagagg ttgtagtgag ttgagattgt aatattgtat tttagtttgg 6780 gtgatagaac gagatttcgt tttaaataaa aaaaaaaaaa aaaaaaaagg aagaggaggg 6840 acgggataga gatataggga agaaggtttt gtgataatgg ggtagagatt agagtatgtg 6900 atgtttttat aatataatta ggaatgttag gcgttattag aaggaggaag gtatggatga 6960 ggttggtttt tagggtttta gaaggaaata gtttttgatt tcggattttt ggtttttgga 7020 attgtgaaaa tacgtttgtg ttgttttaag ttttttcgtt tgtgttaatt ggttataata 7080 gttatttaag agattaaggt gtgagggttt taggaatttt agtagggtaa ggggtcgagg 7140 gtttatttgg tttatagagt tatagtttat ttttttttta ggtttagaga ggttgggcga 7200 tttgtttagg gttatatagg tgtttatgaa agagtttgta ttaggattta gaatttggcg 7260 gtttttattt tagtttttgt ttttttgaat ttttttttgt tcggggggag gtttggggtg 7320 gaggtatttg tataggttat ttgttttttt atttttttaa gggttgaatg gggataagga 7380 gatttttttt tttgggtggg gtaaggtagt ggatgaggtt ttacgagttt ttggtttagg 7440 cgtggtttat aggttttggg ttagtagaag agattgtttt tttatttgtt tggagtttcg 7500 gcgtttgcgg cgagtatttt cgatggtatt ttatttggtt ttttttttaa ggattttttt 7560 gtcgttgatt tggtattcgt ggttattgtt tattatagta aatgggatta ttttttgggg 7620 aacgggtaga cggtattggt tatatatgtg cgggaaggta attttttttt ttgggttttc 7680 gggaggagtt gttttgagtt tggggttttt taaaaacgag agttttagtt tgatagtatt 7740 gggtatagat atttgggttt agtgtttttt ggttttaaga atataatttt atggtttaag 7800 gttttttaaa tttttaattt attttttagt aggaattggg ggttttttgg gaataatatt 7860 ttagtggatt tatttattcg gaatttttcg tttattagtc ggtttttcga gtttttatta 7920 aatttttttt gggggtatac gtcgatgtcg ttggatagta ggtttgcggt gatttgggat 7980 aaggagggag agagatgggt ttatttttgt ggtaagtttt atttatttat tggtgtttgt 8040 tatatgattt ttatattgtg tgttgtttta ggttcgggtt taagggtagg ttttgggggg 8100 ttgtgatatt aattattttt aatttttgtg ttttttggag ggaagagggg tagttgtagg 8160 tgtatttgtt gttttgagcg acgttgtaat tttttagggg tttaaggtta tcgttttgag 8220 tattttttat tttttttttt ttgtttatta tagttttaag aaagtattta gggttatcga 8280 gatttttttt tttgaaattt tttttaaaaa attttcgtta tagtttttag ttttagtagg 8340 ggtttcgttt gtagtaattt tttagttttt tgttagtagt tcgatatggg tacgtgtaat 8400 agaaatattt tagtgagcgg ttgttcgttt gtttaggtat agattatagt tcgtgtgtag 8460 ttttcggtag atatatttat tttgtgtgga ttgttttttt ttgtatatgt tgggaaggtt 8520 tttgatattt ggttttagga cggagtaggt tataggtttt atttatattt atcgaggtag 8580 atgtggtgtc gtagtttagg tatttcggtt ttattttgaa aggtatttta tgtggttttg 8640 atgtgttgtt ttgttaggag gaagagttta gggttgtttt tttgtttgga tgtttttttt 8700 tattttatag taggggtttt agacggtggc ggagaagaag gtggtagaga ttattttttt 8760 tgaaattttt tttttttttt ttttttttga gatggagttt cgttttgtta tttaggttgg 8820 agtgtagtgg tttaatttcg gtttattgaa gttttcgttt ttcgggttta agagattttt 8880 ttgttttagt tttttaagta gttgggatta taggcgttcg ttattatgtt cgattaatat 8940 ttttgtattt ttagtagaga tggggtttta ttatgttggt tttaaatttt tgattttaag 9000 tgatttgttc gtttcggttt tttaaagtgt tgggattata ggcgtgagtt attatatttg 9060 gtttagtttt ttttttattt aataaaaatt aggtagggcg aggtgaggtg gtttatgttt 9120 gtaattttag tattttggga ggttgaggta ggaggatttt ttgagtttaa gggttagaga 9180 ttagtttggg taatatggta aaatttcgtt tttattaaaa atataaaaat tagttagata 9240 tggtggtgtg cgtttgtaat tttagttatt cggggattga gtttgggagg tggaggttgt 9300 agtgagttat gattgtgtta ttatattgta attttggtaa ttgagttaga ttttttttta 9360 aaaaaaaaaa gggggggtat aaaataaggt gggttatgtc gtacggtttt tgttcggttt 9420 tattttttgg aagagagatt tattatttgt ttggtttagg ttttttttaa aatttttttt 9480 agagattttg ttggagaatt ggtattttta taaagttgtt tttgagatat gggggagttg 9540 gagaggttat tttagggacg gtttttagta gttatttggg ttagggatta ttaggttagt 9600 tattcgttgg ggagagtgat tagcggttcg gtttttttga tagtgtgatt tttttagacg 9660 gggtggtttt tgttaggttt gtagcgtttt taggttgtat agaagggttg gggtaagtag 9720 agatggaatt ttattcgttg tttgaagtgg attttttttt ttagggtgag tgtgttcgtt 9780 ttggcgatga tagggacgat gttgattatt ttgtttaggc gttttataaa ttcgatgttt 9840 aggggtttga ggttgaagta gagggatgtg cgtgaggttt atttggggga gcggggtagt 9900 gggggggtat ttatttttaa gtaggtgtcg atatttttag gtgttggttc ggggtttacg 9960 ggggtttttg ttggtaagga tagggtttcg ggtcgagtcg gttacgttgt gagtgtgggg 10020 tagaggaagg atacgggtgt gttttagata taggtgatat tattgtatag gttaggcggg 10080 ttagggttag ttttaagtat tttcgtttat gagttttggg gttttaatta tatttttata 10140 tgtttatata gaagggttgt cgttggttta gtagtcgttt tgttgtgggg ttttggttgg 10200 gaggggagag gtaagagaaa tagaagttag tattagtgtg cggtgttttt gtattaggcg 10260 ggttgttttt ttgtattagg cgggttgttt tttttgtttg tttggtttta gtgagtttgg 10320 ggtttgatgt ggggaaagtt gtgggtggta ggggttggta gggttttgga attggggtat 10380 tatttttttt agttttggag tcgagttttt tttatagtga gaataaatcg gttatatata 10440 tggttgggga gaagttcgtt tcgggtagaa gtttaagtag agatggttaa ggttcgtttt 10500 tgttttatgg gattggacgt tttgggcggg attaggtaat atgtttagtt ggagttttag 10560 ttaaagggtt agtgttgggg agtggtagaa gtgttataga tcgttcgttc gttttcggtt 10620 tgtttagttg gtattaggag aggtttttgt tttttgttat tagttttagt tgaggtaaag 10680 tttggagtag ttggaatagt tgttatagga tcgtaggtga gtcgttttgt ttgggagggt 10740 agatgtttag tttaggagag gtttatggat agcgggttgg ttttttgttt ttgatttttg 10800 ttggtttata gaggatgatg ttagagggtg ggttcgaaaa tttcggtttg ggttttttta 10860 tagattttgg gtgaggttcg ttgtttatta gttaggtttt tttttgtatt tggtgtttat 10920 agagtatggt ttttttaaat ttttgggttt ttttcgttta gggaagtata tttgggatag 10980 taggtgcgaa ggattttttt tatttattta tgtagataag ttatttacgg ttgtttttat 11040 tagttatttt tgttggtttt tggttttttt ttttttagtt ttggtttagg gtgagttata 11100 ggtgtttggt agggggtgta tagggagttg aggatagagg gttcgtgagg ttatgaagag 11160 tttatttgtt agggtatatg tagtttttcg tttttgttga tttttagggg cgacgttagg 11220 tgcggataga gtcggcggga ggaaagggtt tttattaata ttaatagtag tttcgtttag 11280 ttttggaagg ggttagtatt gatttttgtg tttttcgttt aagaacgtat taaatttttt 11340 aaggggtttt atgaggtagg gttcggatga gaaggttagt tatcgttacg ggtgtttggt 11400 tgggggtttt tattttattt gttagagttt ggtttgagaa ggtaggatat agattattag 11460 gttttagaat agtttagggt ttgtttgatt tttagttttt taagacgtag ttgaaggatg 11520 ggggttgggt aggatatttg tataggggtt agtgtgaggt tttggaggtg tagatatggt 11580 atatttttaa ttttatagtt ggcggttatg gtttttgatt tagttttttt gtatttagta 11640 gtagggtaga tagtatcgtt ttgtagtttt aggggataga gggaatttag ggtattcggt 11700 atgaggacgt cgatattgta gggacgtacg agtggtcggt ggcggggatg aagtagaggt 11760 agtagtggac gcgggtgttc gggatgcgtt ttttgcggtt gatgttgatt tttttttgta 11820 ggtatttttc gtattggtta ttgatgaatt ttatgatggg ttgttagttg cgtgggggat 11880 ggggacgagt tagtaggtat atgagatgtt ttttttaagt aggtcgtgta tttttaggat 11940 ttagagttta atattttatt ttttaatgaa atgtatgttt tgggaggttt ggtttgttga 12000 gcggagatgt tatagtttta ttttcggttt tttaaattag ttttttcggg ttggttttag 12060 gtgatgagtt ggggatagta agatttttta ggtaattttg ttttggttta gaatttttag 12120 gtttttgaga cgtgcggttt tggtagtatg ttaggtttta ggaggtgggt tttgtatttt 12180 cgcgggtcgg gaaattttta gggttgattt tgggtggggt ttagggagtt ttgaagtttt 12240 cgttagtgtt tttttttttg gaggggtttt attagttttc gttgttgatg tggttttcga 12300 attttggtgt gttaattatt gttagtttta ttcggacgtt ttttttttta atatttgtat 12360 agagttacgg acgtagagtt agaggggaga cggaagattt ttatagatat tttatatttg 12420 attgatttcg gggtaatttt aggtaggtag cgatgataat taaggagata tcgggaaatt 12480 aatggttttt tttagttaat ttcggtatag gtcggtgacg gtttttttgg gagttttttg 12540 tttgttagat ttttggtgga aaatttagtt gtttgtgggg agtttagtgt gacggggttt 12600 ataggggttc gggatattga tttattatag ttagagtttt aatatgttta atatgttggg 12660 gatggtgggt atagcgagtt ttcgttttgg ggatttggga ttgtttgatt cgggtatttt 12720 tatatcgtat tagtgtttta ggaaggtatg ggtattttat atttttagtt tatttttagt 12780 tattgatcgt gtgtgatggt tttgattttt aatttttgtg ttttaggaag gtaggggcgt 12840 tttgtatttt tagtttattt tcggttattg attgtgtgtg atggttttga ttttttattt 12900 tgtgttttag gaaggtagag gagttttgta tttttagttc gtttttggtt attgattgtg 12960 tgtgatggtt ttgattttta atttttgtgt tttaggaagg taggggcgtt ttgtattttt 13020 agtttatttt cggttattga tcgtgcgtga tggatttgat ttcgatggtt ttggggatgc 13080 gtttttttga ggtgggttgt atcgattttc ggttgatttt ggatttgaag agggtgttga 13140 ttaaggtgga tttatttaag tcgttttgtt ttggggagag gatgggaggt cggttagggg 13200 ttttttcgga gagattagta gggtttgtat atggggtttt ttttatttag gtacgaggtt 13260 ttttagtttg agatttagta gtgtttgggt tatttttcgg taatattttt gttaagtagt 13320 tttcgaggat tttattttcg agtcgggtgt ttagtgattg tgtaaattta tatagtcggg 13380 ttttgatgtt agtataattt aggttatagt ttttttttga gaggtgagtc gggtttggga 13440 gagtcggtat tttttgtgtt ttttgtgttt tttggatagg aggttttttg gtggtttaga 13500 ttttggatag gatagaggtc gggttggcgg aggagtttag ggttgtttag ggtgtattag 13560 gtggtcggga tttttgtagt ttattagggt ggttgtaatt aaagtttagg tgtttaaatt 13620 gttttttttt gatcggttag ggtttgggta agttatttga ttttatcgtg ttttagtttt 13680 ttgatttgta aaatgggata aatagttttt ttttcgtgga gttggtgtga gtattaggta 13740 ggtttacgta tgttttatgg ggtttgtggg gttatgtgtt agggggcgtt ggtttgtagg 13800 gtggtgttat tcgagggata gtgatcgtgt gtgtagatag ttagtttata ggtgattgag 13860 ataaacgagg atgaggaagt agtatttata tgtaatataa tatatataat ttatatatat 13920 tttatatata tattttataa tatatatatt ttatatgtat aatttataat atatatataa 13980 tttattttaa atatattttt tatatatatt ttatatataa tttttataat atatataaat 14040 aaattatata taatacgcgc gcgcgtgcgc gtatatatat atatatatat atatatatat 14100 atatattttt ttagattcgg agttttattg ttttattttg tatagagttg ttttgggtta 14160 cgttagtaat atattaaaaa aaatatttta ggttaggtgt ggtggtttat gtttgtagtt 14220 ttagtatttt gggaggttga ggtaggagga ttgtttgagt ttaggagttt aagattagtt 14280 tgggtaatat agagagattt tgtttttata ttaaaatgta aatattggtt aggtgtagtg 14340 gcgagtattt atagttttag ttacgtagga ggttgaagta ggagaattgt ttaagtttag 14400 gagtgcgagg ttgtagtgag ttaggattat tgttatttta gagtgataga gattttgttt 14460 tttaaaaaaa taaaaatcgg ttaggcgaga tggtttacgt ttgtaatttt agtattttgg 14520 gaggttgagg agggtggatt atttgaggtt aggagttcga gattagtttg gttaatatgg 14580 tgaaattttg tttttattaa aaaatataaa aattagttag gtatggtggt atatgtttga 14640 ggtacgagaa ttatttgaat ttaggatgtg gaggttgtag tgagttaaga ttatgttatt 14700 gtattttagt ttgggtaata atgagatttt gttttaaaaa aatataatat aaaaaatatt 14760 ttaaattata ttgatgtttt gattttgata atattttttt aggaaaagtg tgggtttttg 14820 ggaggataga ggttggtgtt gggaattttt ggtttgaatt gtttagtagt ttaaggacgg 14880 atatttttcg tttatttttt tttgtttatt aggtttgtgt tttggttaat tttaggttag 14940 gagttatgtt aatgttttag ttacgatatt ttagatttag gagatgttaa ttgggatatt 15000 gtaaggtgta tttttttatt attgttattt ttattattat tattattatt attattattt 15060 ttattattat tattattttt attagtatta ttattataat attattattg ttattattat 15120 tattttatta ttttcgttat tattattatt ttcgttattt ttattattat tattattgtt 15180 attataatta ttagtattag tattattatt aattatatta ttattattat tttattatta 15240 ttattattaa tattattatt atttttatta ttattattat tattattaat attattattt 15300 ttattaatat tattattatt tatattatta ttataattat tattattata attattatta 15360 ttattttttt tattattatt ataattatta ttattattat tattattata attattatta 15420 tttatattat tattattatt tttattataa ttattattat tatttatatt attattatta 15480 tttatattat tataattatt attattattt ttttattatt attattatta ttattattat 15540 aattattatt attatttttt ttattattat tataattatt attattattt tttttattat 15600 tattataatt attattatta ttttttttat tattataatt attagtatta tttttattat 15660 tattattata attattatta ttattattat tattattatt attattataa ttataattat 15720 tataattatt attatttata ttattattat tataattatt atcgttatta ttattataat 15780 tattattatt atttatatta ttattattat aattattatt attatttata ttattattat 15840 tataattatt attattatta ttataattat tattattatt tatattatta ttattataat 15900 tattattatt atttatatta ttattattat aattattatt attattttta ttataattat 15960 tattattatt tttattatta ttattattat tattattata attattatta ttataattat 16020 tattattata attattatta ttattattat tattattatt attattataa ttattattat 16080 tattattatt ataattatta ttattattat tattattatt attattatta taattattat 16140 tattattatt attattatta ttattattta tattattatt attattttat tattgttatt 16200 attattatta ttattatttt tattattttt atgattatta ttattattat ttttattatt 16260 attattatta ttattataat tattattatt tatattatta ttattatttt attattatta 16320 ttattattat tattattatt tttattattt ttattagtat tattatttta ttattattat 16380 cgttattatt atttttatta tttttattat tataattatt attattattg ttgtaaattt 16440 tcgaataatt ataatttgtt ggggattttg ttcggggttt agttcgtttg attttatttt 16500 atgggatgat tttattttat ggacgaggaa gttaaggttt atagaggagg agtttagggg 16560 aagatatata agttttattt cgttgagtta ggataaagtt gggatttttt tcggggtttg 16620 tggattttta aataggtgtt tttttatttt gtttgtattt ttgtaggtgg gtatagttgt 16680 tatgggaggg aggagggagg agagtagagt tgttttacgt tttgtttttt attcggtatt 16740 tttgggaggg agtgattttg tggggaatta ggattattgt tttttttagg gttgaaaggg 16800 cgaagaggtt tagataggtg aagtggtttt ttgcgtatta tttttagagg gtaaggttgt 16860 tatagtggta gttacggaag gcgagggttg ttgggttgtt tttttttttt tttggggtta 16920 aagtttcgga agaaggtttg tgttatggtt gggacgtaga ggtttttagg ttttttttat 16980 tttgtttttg gttagggagt agggtagttt tttcgtagtt tatagagatg agttttagtt 17040 tggttattgt ttttgggttt tttttttttt ttttttttta gttatttttt cgggaggtag 17100 ttttgaattt ttagggtata agtacgtttt ttataatagg tagaataggg tgggggtcgt 17160 aggaggggat tttatatttt cgtttttttt tgaagtaggt tgttagtttt taggtagttg 17220 tgagtatagt agggttatga gtagtcgggt tttatgaggt tataggaagt agagaggata 17280 ttaagatttt aggggagtta gggtttagat tagtgtagaa gaggaaagaa aggtgtcggg 17340 ttggtaggtg tgggtttgcg tttatagagt tgggtaggaa ggacgtgtac ggttggtaaa 17400 ggttagagaa ataggttcgg tttgagaggt gtttagatat tttgtagaaa tttcgtaagt 17460 ttatttttgt ttagggtgtg atttggcggg ggtatttttt tagatttttt tttggatttc 17520 gtggagtggg tagaatatag ttttgggagt taaaacggtg gttgcggttt tttgttttgt 17580 gagttaagga attttggtag ttttttttga gtttcgtttt tgtttggaaa acgggacgtt 17640 ttttttatag ggtttttgtg aggtttgaat gggatttggg gggttttgga aataataggc 17700 ggtttattgt agattttagt ttggtttttt tattttgttt aggtcgtgtt gatcgacgat 17760 ttttcgtggt gatttttagt ttttcggggt tattaggggg tgtggaagtt acgaggtttt 17820 aattttaggg tagagttgaa gttgagttgt tgggaagttt ttggtcgggg tgcggtgggg 17880 tgcggtgggg agtttggagg gttaggttgg agtaatagtg aggggatagt tgttatagaa 17940 ttttttgtat aagttgacgt tattgtttag aggtagcgat tatttattag gatttgtttt 18000 aggtcggttt gggtttttta aagttatttt aggggttttg gatgtgtagg ataggttttt 18060 ttgaggagtc gttggaggtt gtgggttttt tttaggcgta tgtatgtata cgtaatgtta 18120 ttggtaattc gtttttgagg ttagggttgt tgttttattt tatagaaggg aagattaagt 18180 ttaaaggttt gtgggtcgtt ttgggggttg aggttggttt tcggtattgg ttgagtggta 18240 tgtaaggtga ggatttatcg attattatga tgttgaattc gaagttttgt tttatggttt 18300 ttcggcgtat ttgttttagg atggagttaa tttttacgta gtcgaagttt atcggggttt 18360 tttcgtttcg tgatgtaggc gtttgtttga gttcggtatt tttgggggtg tcggttatgt 18420 cgttaacgta gttgggagtc gttttagtgg ttggggaagg aatagtagag gagttagagc 18480 ggaatagggg tttatatata ggcgtttgtt aggtggttgt tatatttatt tttggatggg 18540 gaaattgagg tattgaggtt tagaaaggtt aagcgatttg tttaggcgat ttttgagaat 18600 tttttcgggt ggatgttttt ggtcgtggtg ttttttaaaa agttgttatt ttgtagttac 18660 gttgtttttt tagtaaagtt ttatttttag atttttaagg ttaggttttt ttattttttt 18720 ttttaggagt tgtgttaagt tgggggtttt ttgcgtttta aggtagggtt gattttgaat 18780 ttttgttttc gtattttgga gggttgttta gataagggtg gagggtgttt tttttttttg 18840 gttttttata ttgtttcggg ttatttaggt ggatttggtt ttttttttta tttttattta 18900 gataagttgt atcgtttgtt gttatttaaa ggttttagaa gtcgatttac gagttaagat 18960 ataggaggga tggttttgta agaaacgggg atagaattag cgtgtgtttt cgttttttat 19020 atttttatgg atggttttgt aagaaagggg gatagaatta gcgtcggttt ttatggagtt 19080 gtgtgtttaa ttttatagaa cgagttagta gttttgggag aaggaaaagt gttgggtgta 19140 gggcgggtgt ttggatgtag agttgttttt gggtttatgg aggagggggg tttttgtatt 19200 atatttgttt ttttttggat tgatttaggc ggtcgttttg tgtgtttggt tagcgtttac 19260 gggttgtata tttataggtt aagattaagt tttatttttg ggtatgtggg gtacgtggag 19320 ttgaattttt cgaaattatt aaagtttttt ttgtttgtag gttttttcga tggttttgtt 19380 tttggttgtt gttaagatat tatatacggg ttagaggttt ggggttgggg gcggacgttc 19440 ggaagacgtt tgttgaggat ttaggtgttt ttatatagtg gggttttagg ggtatttagg 19500 atggggttgg tttttattag ggttggttgg tatacgggtt aggttttagt atattttaga 19560 ttcgttatat ttattggtgt atgcgtatgt aggtgtagat aattcgttgg ttatagaggt 19620 ggtgtttttg ttagttttta taggttggag ttgtttttgg tggtttttag tttttacgta 19680 ggttgggcgg ttgttgtttt gtgttttcgt ttttgtttgg gtttatttag gttttgtttt 19740 gtttgcgggg agatttttgt tttattttgt tttttaggga ggatttggtt ttaggtattt 19800 tgcgttaaga tagggattat acggtacgtt tttaggtagg gtttttttcg ttagtttttc 19860 gggaggggag tggttttttt ttgggatcgg tgggtattta gtaggggtag ttatagggga 19920 gtggagtcgg cgtgggagtt agggttatag tacgggaggt tgtagggggt ttatttttcg 19980 tgataggtaa gtgagtagtt tttttagata ggaggtagtt ttttcggttt acgtttattt 20040 tttattttgt ttagaaggtg ggaggtaggt ttttaggtta ggaggggtag tgggagattt 20100 tagtttaatt gtttttttat ttgcggggta agaatcgaat ttaggaaatg tttattgagt 20160 tttttggttg tagtttgtat ttttagtcga tttaagttat ttttttcggt ttattttatt 20220 ggagcggtta gagggtgtcg gagggaggtt ttttaggttt gaggtattag aggtgagaga 20280 ggaaaagatt ttggaagtta gaaattgggg gttggtttat ttttataggt attttttcgt 20340 ttttttagtt tttatagggt ataggaattt ttattttatg gaattggggg aataaaggaa 20400 taatataatt ttttgttggg aaatgttaag ggggggttta tatattttta ttgttgagag 20460 taatatttat aggcggattt ggaggttagg gttttttttt ttgtgttttt acgtggtttt 20520 tatttaggtt acgtagtttg gaagttttta gggttttgtt tttgtttttg tttttttttt 20580 agaaatattt ttttttgggt ttttaggatt tttaaataaa taaagatata gttttgtatt 20640 tggttatgga ttatgtggtt ttggggtcgt tttttgaagt tagatatggg gttttgtttt 20700 gcggggtagt agtttagttt ttatttacgt gatcgaaaat cgtttttatt tgtttgtggg 20760 tttgagagtt attttgtttg ggattgggat tagtttttat tcgtttttat ttttttttag 20820 tattttttaa ttttttttag taggatttgg ggggaggcgt tgttttttga attttttttt 20880 ttcgttttta acgtttttgg agtttagagc gagggagggg tcggtttagt tgtagttggg 20940 tttttttata ggtattagta tttattgtag aaatttaaat taaattaaat attttgttta 21000 ttaggggttt cgtttgagaa ataataatat aacgtagtcg agttttattt ttgttattga 21060 cgtagggtag tggtttgttt tttgtatagg tgagagttat ttttgtaatt tttttttcga 21120 gaggcggttt tgtaggtttc ggttggttcg taggtaggta cgtacgtaga gagtaatgta 21180 agagttcgtt tcgttttttt atttggttag gtgagttttg gggtttgttt ttaggatttt 21240 taagtgggaa aagtagagat ttttatattt agagatattt ttattttggt tttaggatat 21300 tatggtgttt agatagttgg aaataatggt aaagattatt tattttattg tttgtgatta 21360 cgatatcgtt cgaggtttgc gttgtttagc gtggtagtta ttggttacgt gatttttttt 21420 tttaattgtt ataacgtttg ttacggttat tattttgaag tgtgtagttt agtggtgtta 21480 agtatattcg tattgttgtg taataaattt ttagaatttt tttattttgt aaaataaatt 21540 gtttttatta aataattttt tagttttatt ttttaagttt ttggtaattt ttattttgtt 21600 gtttttttga atttgattat tttacggatt tggtataagt ggaattttat aggattgttt 21660 ttttgtgatt aaattatttt atttagcgta atattcgaaa ggtttatttt tgttgttgta 21720 ggtattttaa tttttttttt acggttgagt taaatttttt gtatgtttta tttttttttt 21780 tttttttttt agatagagtt ttgtttttgt tgtttaggtt ggagtgtaat ggcgcgattt 21840 cggtttatcg aaatttttgt ttttttaggt ttaagtaatt tttttgtttt agttttttaa 21900 gtagttggga ttataggtat tcgttattat gttcggttaa ttttgtttta gtagagacgg 21960 ggttttttta tgttggttag gttggttttg aatttgtgat tttagatgat ttattcgttt 22020 cggtttttta aagtgttgag attataggcg tgagttatta cgttcggttt gtttcgtttt 22080 tgattttttt atttatttga tcgcgggtat tcgggttgtt tttattcgtt ggttattgtg 22140 aatagagtcg ttatgaatgt gggtgtataa atatttttag ttttttaaga tgttgtgtat 22200 ttttttgaat ttatatttag aagtggaatt atgggatgtt acggtggttt tagttttcgt 22260 tttttgagga attgttatag tgtgtttata agtgattttt gagtatttga tattgagtta 22320 gtttaattga ggaacggaat ttttattttt atttaaattt aaatagttat attttataaa 22380 tggtaattat attggatggt atagaatttt agtttaattt attttttatt aatggggaaa 22440 ttgaggttta tagagtgatt tttttttttg aaatgttatt gtaagtggtt aggttagtat 22500 aagattttta ttgaatttgg taattttgaa attttatatt tttgtttgta tgatatgcgg 22560 ttaatatttg tgattttttt taaagatcgt gggttttagt aagacggtag ttgtttcgtt 22620 gagattttta tcgtattttt aggtttcgtt ttgttacgaa tacggttgtg taaggatttg 22680 tttgggtttt tgttttttat tttttcgggt atttagatta attattagta gtatttacgt 22740 cgatttttag aaaggttttg atttggatag taattgatac gttattttat agttaaagta 22800 aaatgtagag tttttttttc ggtttcgtag ttgggagtta gaggttttag gttttggttt 22860 ttggtttaaa gtgatttttt gtaagttttt ttagtttggt aaataggtta tgtatttttt 22920 gatttttttt ttagtttttg ttttgcgagt ttttgggtgt tcgaggttgt ggtttattta 22980 gtgatatttt tagtttttag tgtagttcgt gagtagtata atatattcgg ttttagaaat 23040 aattaatata ttcgttaata gatgcgtgga gaaatttaac gtgttgagtt aatatagcgg 23100 attatttttt agttataaaa aggtacgagc gtgcgttaat atagatgaat tttgaaaata 23160 ttttaattgt aagaaattaa gtataaaaag ttatattttt tagggtttta gttatatgtt 23220 tagaataagt atatttgtag ggataaagcg tagattggtg atttttaggg gttgggggag 23280 ggggagtgat tgtgtatcga ggatggcgtt tttttttggg gtgaggaaaa cgttttggaa 23340 ttagaggtga tgtttataga aggttgtgaa aaaatgttat ttaattgtgt tttttgaatc 23400 ggcggatggt gtaatatgga aattatattt ttatgaggac gggagaggaa gggaaagaag 23460 ggaaggaggg agggggaagg aaatagggaa ggaaggaaaa aagggagggg aggagggagg 23520 gacggaagaa gggaaagaag gtagttattt ttagtggagt tggattgaag agtttaatgg 23580 gtgtagtaaa ttattatggt atttgtattt ttatgtaata aatttgtacg ttttgtatat 23640 gtattttaga atgtaaagta aaataaaata aagagtttag tgttttttat aagtgtttag 23700 gagttagttt tatagtttag aggatagttg aggtttagag gttaatattt aggtttgagg 23760 tttttaagtt ggtgtcgtta gattatgttt tagataaatt tttttatttt tttgtagtaa 23820 gggtgttttt agggtggtag ttaggcggag gtgttaggtg gcgggagatt ttgatagttt 23880 ttttgtaggt ttttattttg aatttaggtt ttatgttagg gtttttttgt tatttattgg 23940 cgttggtggt agtaggttat cggtttcgtg atggggattg tttttaaatt tgtttatttt 24000 ggggattagt tttttttttt tcgtaggcgt ttattgggtt attttttttt tagagttgta 24060 ggtgggttta aggtagggat gaaagggttg taatttacgt agttttgagt tagtattttt 24120 tgggaatatt tgtatttagt gataaatttt tattttaatt ttaggatttg tcgaggatga 24180 gggaattaga ttgttgtttg tggttgggac gggggttgta ggatatttgg ttgggaggta 24240 gtgtttagag aggaggtagt tattggatat gatatatttt aggggtattt atatttatta 24300 tagttttagg gttgattttg gtttatttgg tttggtgtcg agagagggtt tgatatagta 24360 ggtttgtaaa gtttgatttg gaaattaaga tttaggggtc gttttttttt gtttattttt 24420 ttttgtgtgt tatgttgttt ggtttacgtt ttagaaatgt ttatataagt tttattagtt 24480 ttgttggtta aatgtagaga tggtgtcgtt ggggtaaggg attttgagtt atcgtttaat 24540 gttattttta gttttagggg agtgatagtc gggtttgtat tttaggataa agtgtttagg 24600 gttaagttaa tgttattttt ttgttttttt taaatttaat ttatatttgg tttttagagt 24660 acggatcgaa atggttatat ttttatatat tttgtttgtt attgttaatg gtggttaagt 24720 agaatgtaag gttatttttt ttttgtttac ggaggtttgt gaagttattg attaggttac 24780 ggtaggggag tcggtggtat ttattatatt ttgttagttt tttaggttcg tgtttaggag 24840 aaagttgtcg gtatttatag ttggtgtttt tgtttcggcg aagatttttt tgtttttatt 24900 tatttcggtt tagcgtgggt ttagtagttt ttttattttg tttcgtaata atgtatattg 24960 gagtagtttt tagttgtttt ttttttgtag gtttttttga atttagattt tggggttagt 25020 atttttgcgg tagttttacg gttatttgta ggttttttta gaaatttgag tttatggggg 25080 tattttaggt tttataaatt aatagatgtt ttttgttttt tataaagggg ttttttaaag 25140 ttgagtgagt ttttgatgta ggtaatgtta ggaggatagt gttcggttag ggttgttttt 25200 tttttttttt ttattttttt gggtgtttgt aaagtttttt agatttttgt tgaattttgg 25260 ggaagttttg tttcgtaatt agggtttgtt tttttcgttt ttatatagag tttgtttttt 25320 gcgtttagat agttttttta cgatggtaat tgaataatga tgtgtgcggt ttttttttat 25380 tataattttt ttatataggg tttgtgaagt tagatatttt atttattacg tttattttag 25440 ttcggttttt tttagagtag cgtagggttt acggtaagtt tcggtaaaaa gtttggtgaa 25500 tgaatgaata aatgaagaaa taaagtttat tatagtagtc gaggtttatt gggggttttt 25560 tgtgttaggc gttattttaa tttttttttt tagagagtgg gttttattaa tgttggttag 25620 gttggtttta aatttttggt tttaagcgat ttttttattt tggtttttta aagtgttggg 25680 attatagata taagttattg tatcgagttt taggtgttat tttaaacgtt gtttaggagt 25740 tattataatt gatggattat tatataattt tataaggtag ttattgttat tgttttattt 25800 tatagataag gaaatcgaga tcgagagggt ttttgttaat tatgagggtc gtaaagcgag 25860 taagcggtag agttaggatt tgaagttagg taggtgagtt ttaggttgtt gatttttttt 25920 ttaggttagg ttttcgggaa ttatggaaag gttggagaag tatggggttt ttgtagttag 25980 gatttagaag gtgtagttgc ggtgtaggta gtttagtatt gaggttttgg tttttagttt 26040 tttttttagt tgtttttttt tagggagttg gaggtagagt tttgaattgt taggagaaga 26100 ttttattcgt tagttaggga aagttgttag ggtttttttt agggtttaga gttattttag 26160 gtttattaaa gtatattagt attttagttt ttataatttt ttttgtaaga aagatgatgg 26220 tattagttat tgggtcgggt tgggggtttt agattttagg ggttttttta ggtttgttta 26280 tggttttttt aggatataga tgtttatttg agaaatttta gtgtattagg ggttttatag 26340 ttaaaataaa gaggtagagt tgttttgggg tttttgttaa agtttttagg tagatttatt 26400 tagtagatat taaaatgttt attttttatt tgaaaatttt atttttagga ggtcgtttta 26460 ggttgggttg ataaaattta tagagatttt aatgatgatt ttttatttta ggtatgagtg 26520 agtgggtgga gggagaagtt attgttaatt attaatagtt taggaaatgt aggtaaagga 26580 aagagaatgg taaggcgata gggttggaaa ttagatatac gtgtagaggt gagtagattt 26640 tagagaaaga attgttttgg aataagatgg taaagaaatt atagataata atggtagacg 26700 atgattttgg ggttttagtg gattaggatt ataatattga tttatttgat aagtatttat 26760 tgagtgttta ttttatagta ataaaaagat gatattatag gtttgagagt agttagaatg 26820 aaaatagtgg tggtatatgg gaatttgaag tttatttatt taaatgttta ttagtcgaga 26880 ttttcggata gatttgaagt agtttttaat atgtaaggaa tttataattt gatatagtag 26940 tataggatat gtgtgtgtta taaatttttg gtgaaaagta aagatttttt ttagaaaagt 27000 atatattgaa gatagataga tagatatata cgtattttga acggtttatt aaagaatttt 27060 taggttcgtg gattttagtt aaaaaaataa tttggtattt tgggaggtcg aggcgggagg 27120 atcgtttgag tttaggagtt taagattagt ttgggtaacg tagcgagatt ttatttttat 27180 aaaatgaaat aaaataaaat gagaattaaa aaaaataaat aaatttggtg tgatgagaat 27240 ttatagaatt taatagggtt attttagtat tatttgtagt attttttaaa tttttgatta 27300 tatatataaa gttttgggtt ttatagttag agaagaggga gagtaggtta aaaataatta 27360 tttaaggtgg aagatgagtt tgagaaataa agaggtaaga ggagaagatt gaggttagtt 27420 gttttttatt tttgagtttc ggtaggagga agtttttaag tgagaataag ttgttgtttg 27480 cggagtggat tttagagcgg gtggatagag acgataagga atgttatttt tggggggttt 27540 tgaaaatagg atattttttt attttaattt tgttttttat tgtattgtgt ttttattgat 27600 ttatttaagt tattataaat attttataaa tgttattggg gattttttgt ttttttttaa 27660 agatggaaat attgaatata aatgattaaa ttgtgtaaat gtgtgtgggt gggggattaa 27720 ggattgaatt tttaaaatgt atatagttta tttaatttgt taattaattt taaattaaat 27780 tatattttat attttgtatg ggataggaag cgttttttta aagtttggtt aggatttggg 27840 atgtcggaaa tttgagattt tgtttttttt ttttgagata ttttgaaatt ttgtttagaa 27900 atcgagtata atggttttgg ttttttagag aaagatacgg atttgtaaag gtaaagagtt 27960 gtattttttt tcgagttgga gtttttttcg gtttttatta tggggtttaa ataaaattgt 28020 agttttatag tttttttgtt ggtgtttttt tttttttggt gattaataag gtggaagagt 28080 taataagaat tttgtgtgtt tttttgtagg atttggaagg gataggtggt gtgagtttgt 28140 ttttatttag tttttttttt tatttattta ggggtcgagg cgttttcgag gtagggggcg 28200 ggggttttta tttttattgt cggttaaggt ttttttagtt tttttttcgt taaatttttt 28260 taagtaaatt ttttttttat tgtggaggaa ggaattttaa gtagttttgt ttttttgtta 28320 gtacggtttt aattggtttt agtcggtaaa gttaaatttg gataaggttt aagggttttt 28380 tatattattc gtcgtttttt ggaagaggtt tttttttgtt tttttatttg taatttatta 28440 tttttttagt ttgagttttt ttatttaggt ttcgcggttt attgagatat taattttggg 28500 ttagagtaag ttttgatttg taaattatta ttatttattt tttaaagagt tatttttaga 28560 atttaggttg tagggagggt aggttaagga tgaatttttt gatttttggt gcggtgtgtg 28620 gtgggggggg ttattttata ttttgttttt tgttgttttt ttgttttgtt ttaggttttg 28680 aagtggattt attgtagagg gagggttagg gaatggtttt gatgtttttt ttattttaag 28740 gaatttttta gtaggagcgg tttttatttt aaagtaattt taagatttag ttcgtgttag 28800 ttttttagtt atgtttatag tggtttgtta attagagatt tttttagttt ttggtaaatt 28860 tgtaaattta taaagagaaa gaaaagtttt ttcgtgggtg ggtggatatt ggttatttgt 28920 tataggttgg aatttttttt tattagggat gttttttaag taggggttgg ggagggtagg 28980 gtttagagtt tttttttttt tagttttttt tgttattagt agatttgtta gtagatatat 29040 agtagagttt agtagtgagg taataatagg ggttgtgggg gttggggttt cgtttttttt 29100 aatttatgaa attatttgaa ataataaaat ttagataagg gtttttgggg tgtaataggg 29160 tggttttttg ttaggtgttg ggtagaaaaa aagttttttt ttaatttttt tttgttgtgt 29220 agattagttc gggttttggg gatgttgtag aggttgtttt atgtttaggt tttttagaga 29280 tagtaggggg ttggaggtac ggtttgtttg ggggtagggg ataggtaggg aggggtatat 29340 ttttgggtta tgagtaggag tttgattaaa tgattttttt aggagggaga aagatatcgt 29400 atataattgt ttgattatag ttagaggggt tggaaaggtg ggggaaaggg gtgaaggggt 29460 taattgtttt aggtgttttt aatttatgta gtatttattt ggattgataa gagttgagag 29520 attggaattg tttttttttt tcgtttttag gttttgtttt aggagttttt ttgtttagga 29580 gtttgggagt tgaggaggtt tggaagtagt gggtttatag tgttatcgtt ttgggaattt 29640 atagtgtttt ggatgtggtt ttttcggttt tagttttgta ggtagtttat ttggattgta 29700 tttatttttt agaagagttg tttagaattt tgtatgttcg aaagaaagat taattaaaga 29760 agtgaggaag ttaaagagag gtttatgaaa gtttatgacg tattttttaa gtgtatattt 29820 tagtaatttt aaatgttttt tgaagtaagg atggggatgg atggttggat aaatggatgg 29880 gtgtatgggt gtgtgaatgg gtgagtgggt gggtggatgg atggatagat ggatgaatgg 29940 atgggtaggt ggatgaatag gtaggtgaat ggatgggttg gcggatgaat gagtaaatgg 30000 atgaatgatt ggatggatgg gtggatgagt agataggtgg atgagtgaat tggtggatga 30060 gtggatagat ggatgagtgg atgagtagat gagtgaatgg gtggatgagt ggatgggtgg 30120 gtgagtggat gagtagataa gtggatgggt ggatgagtgg atgggtagat ggatgggtga 30180 gtggatgcgt ggatgagtgg atggacggat gagtggatgg atggataagt ggatgggtag 30240 atgagtggat ggatagatga gaggatgggt agatggatgg gtgagtggat gggtgggtga 30300 gtagatgggt ggataagtgg atggatagat gagtggatgg gtggatgagt ggatggatat 30360 atgggtggat agatgggtga gtggacggat gatgagtgga tgggtggatg agtggatggt 30420 tgagtggatg gataaatggg tgaatgagtg gatgggtaga tgagtggatg gatagatgag 30480 tgaatgagtg gatgggtgga tgagtggatg gatagatggg tgaatgagtg gatgggtgga 30540 tgagtgaatg agtgaatgag tggataggtg gatgagtgga tgggtggatg agtgtataga 30600 tagatgggtg gatgggtgga tgagtggatg ggtgggtgag tggatgggta ggtggatgag 30660 tggatggata gatgggtaaa tgagtggatg ggtggatgag tgaatgattg tagataggtg 30720 gatgagtgga tgggtgaatg agtggataga tgggttgata ggtggatgag tggatgggtg 30780 gatgggtggg tgcgtggatg ggtgagtgag tggatgggtg ggtgggtggt aagatgggtg 30840 gataggtata tggagtttat ttaaggagtt ttagaaatat atatatattt ttttatttta 30900 gatttttttt aggaaaaagt agtgtgtatg gatcgttatt tggttatatt ttgagatagt 30960 tatttttatt ttttttggaa tatcgtttgg ggggatgtag tatagggtat ttaagtaatt 31020 tttgagttta gggtagagat attaggaagt agtaggtagg tcgtgatttc gtaggtttgt 31080 tttatggttt ttgttgtttg tattatggta tgaagtttag atgtattttt ggatttgggg 31140 ttttgattag atggagttat taattttttg aagaatgaaa tatatagggg ttatttttgt 31200 tttttagttg tagggaatga cgattattta gttttttttt tttttaaatt ttttttaggt 31260 ttttgtgtat ggttttgttg attttttttt tgtttttggt tattttttta gtttttgtcg 31320 tttttttttt cgtttttatt tacggagtta gttttggtgt tttgagagtt ttttttttta 31380 gttgatttta tttagttttt gagtatttaa tgttaataat gttatttttt ttgtttagat 31440 ttatatttga gtgttagttt gatttataga cgtgtttttg ggtttcgttg tgttaggttt 31500 tttgttgggt tttgggtatt tgtagttatt gttattgtta agttttaata tttgaaggta 31560 ttttgaattt aatgatcgtg ttttaggttg aattttggag tttttatttt atttgttttt 31620 tattttattt tttatttaag tgaatagttt ttttagttaa tagttattgt agttagattt 31680 ttaggggtcg ggtttgggtt ttttattttt attatttcga atttatttat ttattttaaa 31740 tttttattaa tgttaattta atatatttta tagttattat tattagttgt ttttgttcga 31800 attttttttt tttaaagtat tagggggcgt gtgtaaaatt tattaatttg atgatttttt 31860 tttatgaagt cgtgattggt ttttattgta tttgggatat attagatttt tgtggtttta 31920 gaattttgtt tattatcgac gtgttgtgtg attttgagta agtaatttaa ttattttgtg 31980 ttttaatgtt tttatatgtg aaatgggata ataatatttg ttttataaga atgttgggga 32040 ttaaatgaga tatttattta tgaagtatat agtgttgtgt ttggttagta aatgtttgaa 32100 gtttttgtta ataaaatata cgtttttaat ttatttttta gtttttattt acgtatagtt 32160 tttttggttg ttttttagtt tttttaataa ggttatttat agaggttttt tttgtcggga 32220 ttattttttt tttatgttgt ttttagaatt tttatttgtt ttttcgggat agtttattta 32280 tattgggttt tttagttttt gttttgtttt gttttgtttt gttttttttg agatggagtt 32340 ttattttgtc gtttaggttg gagtgtagtg gtattatttg ggtttattgt aagttttgtt 32400 tttcgggttt acgttatttt tttgttttag ttttttgagt agttgggatt ataggcgttc 32460 gttattacgt tcggttaatt ttttatattt ttagtagaaa cggggtttta tcgtgttagt 32520 taggatggtt tcgatttttt gatttcgtaa ttcgttcgtt tttgtttttt aaagtgttga 32580 gattataggt ttgagatatt acgtttagtt taggtttttt agtttttata tacgtggttt 32640 ttcgattgtt gtttggggtt tgtcgtattt attatttata aaattttata cgttcgaagt 32700 atttagtaag acgttgtgaa tgagtgaatg aataaatgaa tgaatggtta gtttgttgtt 32760 ttttcgttcg gtttttcgtt ttttttagat tagtatgggg gtagttacgg ttttcgttta 32820 tttcggtaat atcgtttttt ttgtgtcggt cgcgttggtt agagtttttt tttacggcgt 32880 tttcgcggtt tcggtgtgtg gtcgtttgtg aatgagattt atgattttcg gtttttatta 32940 tttttttgga gttataaagt attaaggcgg aaggatggat gggttttttg ggatagtcgg 33000 ggtgggaggt cggtttagga aatttttttt aggaaatggt tagtgtggga tgaggcgttc 33060 ggtgggaggg gagtggagtg gggatttggg gtttggttgt tttgtagtta gggattttaa 33120 tttttatttt ttttttcgtt tattttttaa ttttagtgtt gggtttaggg tttttggggt 33180 tttttttagg aatatagaag atatagtaag gattagggat ataggatagg tagagtttat 33240 gggtaggagg tttttagtta gtatatttga gtttatgttt ggttttaatt agatattgag 33300 attttggtta ggttattttt tacgttgagg taggggggtt ttttagaggt tattggtttt 33360 taagtatcgc gtggaagata tgttacggag agttagtatt ttttgagata ttagtagaag 33420 gttagacgtt tcgcggttta aggatgattt ggttttagcg tttatttatt tgtcgttttg 33480 tatgaaaagt ttgacgtgat atggtcggtt ttagcggaag agtgattcgg gaatcggtag 33540 agcggattta gtaattggta aattggattt agtaattgag atattgttag gggtttggta 33600 gaagtttttt aatgtattag atttagtttt gatttttata gagtttagtc gagtattaaa 33660 aggtgtagag gtcgagttga gtattagggg aatattgatt ttagggttga tcggtgttgt 33720 gcgtgtattt tatagtttat agacggttta tatttattcg atcgtatttg attttttttt 33780 gcgaggtttt ttttagattt ttcgtttttt aaagttatta gttgtgtttt ttgaaattag 33840 agtaaagtaa taaaattgta gtaatagcgt gtttttatga acgttgtgat gttagttggt 33900 taaatgaggg agtttttagg gttttttata ttgtttcgat tttgtgtgtt ttttggtttt 33960 ggtttatttt ttatattttt tgtttttttt tttttttttt ttttcgagga tttagggttt 34020 ggggttgatt tattgtggga ttttaacggt gattttttgg aagaaatgtt cgtttttttt 34080 ttttatttag tagtgatttt tggttcgttt acgtttacgt agttaatata ggtagtagtc 34140 ggaatttgga agtttttggg gtgggagttt gttttttttt aggttttttt agttcgaatt 34200 tcgggaagga gttatattta tatggtaatt ttttttaagg ttgggagggg gaaggggttt 34260 ggttcgggtt tgattatttt tttgaggttg cgtttattgg gttttttaag ttagttgggt 34320 ttttcggttg tatttttgag ggatggtaat agattatagt gtaaattgtt tatcggttgg 34380 ttgggtagtg ggtgtttaga tgcgggttag ggttttcgtt ttataggttg tgtggtggtt 34440 taaagtgggt atttttatgg gtatatattt gtgttatagt ttattcgtgt gtgtgtgtgt 34500 gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtgtgtgtga tagtttagaa atatggtaat 34560 ttatagtttt tttaagacgt tggttttggg agatttgttt atttgggggt tttagtattt 34620 ttagtttttt ttaggaaggt tttgtttttt ttggtttgaa gttggtttta gggaagaatt 34680 tttttagaaa aataaaagtt atttttttta gttttagttt agtttttttt taggggtgag 34740 ttatattaaa tttatttttt tttttttttt ttattttttt ttttacgttg taattagttg 34800 taagtggttt atttatttag gtttgttagt ttattataga aaagatattc gaattttgta 34860 tttttttttt ttgatttgtt ttgggtttta ataggtaaag gaaattggaa gttagtagtt 34920 aggatttagt tgtaggtttt cggggttatt ttgcgttttt attttagttt tatttatttt 34980 tgcgttgatt taatgtttat ttattttagt ttatggagcg aggtttggat ttaagataaa 35040 ataaaggggg ttttggtttt ttggggttta tagtgttcgg tgtcggcgag ataattttag 35100 agtatagtat agagaaatgg ttgcgatacg gattcgtagt atttggttgg ttaagtatag 35160 taatgtattt ttattaggtt tgggtttttt agtagatata tggtttaaag gttggttggt 35220 taaattatat gattttgtaa ttatttaaga gaaatgaaaa tatgtttata taaaaatttg 35280 tagattagta tttattgtag aattttttat aatagaatta tgttaaaaag tagaaataat 35340 ttaaatgttt attagtagat gaagagatat atagtgtggt ttatttacga tggaatatta 35400 ttcggttatg aaaaagaatg aagtattagt atttgttata atgtggatga gttttgaaaa 35460 tattttatta agtgaaagga gttagatatt aaggttatat attgtacgat tttatttata 35520 taaattattt agaataggtg aatttataga gacgaaggta gatgagcggt ggttaggggt 35580 tgagagttcg gagttgggaa tggggattgg ttaatggggg tagggttttt tttggggatg 35640 atgaaatgtg ttgggattaa tggcgatggt tgtgtaattg tgatggttaa ttttttgtgt 35700 tagtcgggcg tagtggttta tgtttgtaat tttagtattt tgggaggttg aggcgggtgg 35760 attacgaggt taggagattg agattacggt gaaattttat ttttattaaa aatataaaaa 35820 aaaaaattag tcgggtgtgg tggtgggtat ttgtagtttt agttattcgg gaggttgagg 35880 taggagaatg gcgtgaattt gggaggcgaa gtttgtagtg agttaagatc gcgttattgt 35940 attttagttt gggcgataga gcgagatttc gttttaaaaa aaaaaaaaaa aatttttgtg 36000 ttaattggat tgggttatgg ggtatttagg taatcggtta aatattattt tgagtgtgtt 36060 tgtgaaggtg tttttggatg agtttaatat ttaatttttt tattttttag aaagtttagt 36120 ttattgttag tatttattta attttatata aatacgtttt ttgaggttga agtaaatttg 36180 attggatgtt ttgtgtgaaa attaaatata aaaattggtt aggcgtggtg gtttacgttt 36240 gtaattttag cgttttggga agtcgatatg ggttaattat ttgaggttag gggttcgaga 36300 ttagtttggt taatttggtg aaatatcgtt tttattaaaa atataaaaaa ttagttacgt 36360 gtggtggtag gtattttgta attttagtta aatttaggag gttaagattg gagaattatt 36420 tgaatttagg aggtagaggt tgtagtaagt cgagatcgtg ttattgtatt ttagtttggg 36480 taatagagag agttcgtttt aaaaaataaa aaaattaaaa agaaaaaaaa ttttttaaat 36540 tgtttttgta gttattttta agtaaaataa tagagttatt tgagtcgttt attttggaaa 36600 aattagattt attaaatgaa tttttagtta ataattgatt aagaataatg ttaatattat 36660 ttgtaggaat gttgtgtttt ttaggatttg atatttttag cgatcgagaa ttattatttt 36720 tttttaaatt ttatttattt atttattttt tgagatggaa ttttgttttg tcgtttaggt 36780 tggaatgtaa tggcgcgatt tcggtttatt gtaatttttg tttttcgggt ttaagtaatt 36840 tttcggtttc ggttttttaa gtagttggga ttataggtgt ttattattac gtttggttaa 36900 tttttgtatt tttagtagag atgggatttt attatgttgg ttaggttggt ttttaatttt 36960 tggttttagg tgattagttt gttttagttt ttttaagtgt taggattata ggtatgagtt 37020 attatattta gttgagaatt attatttttt tttaaaggaa atattattat taaaaatgga 37080 atgttataaa tagaatgatg ttttttgttt ttaaagtcga tatattagag tgatgtgaaa 37140 ataataataa aagtaagata tttttcggta aatttatttt ggggtgaacg ttgtagttat 37200 aagtattgtt ggtgagtatt ttcggggtaa ataggaaaag ggtgtaatta ggagtttggg 37260 taaagtagat tgtgtgtttt gatgggggtg ggttttattc gattagttga aggtaatagg 37320 gtttggaacg tatattttaa gatatagtgt tttggtatag taaatatttt tagttgaagg 37380 aatttaagaa atggtaggtt taagaagaat ttattgattt gttttttttt tgaagtagat 37440 tataagtttt ttacgtaaga ggtgtttttt ttatatttag cggaaaggaa tagttttatt 37500 tttagagata gaggatttga gaggggtttt agtatatagg ttttgtcgag atttttacgg 37560 gtttattgtt tagtttattt tttgttgttt tgttatagtt ttttacgatt ttttattttt 37620 tattaaattt agtataaaaa cgtttaggtt taggttaggt atagtagttt atatttataa 37680 ttttagtatt ttggaaggtt aaggtggtta gattatttga ggttaggagt tgaagaatag 37740 tttggttaat atggtaaaat tttattttta ttaaaaatat aaaaattagt cgggtgtggt 37800 ggtatacgtt tgtagtcgta gttatttggg aggttgaggt atgagaatgg tttgaattta 37860 ggagatagag gttgtagtga gtagagatta tgttattgta ttttagtttg ggtaaaagat 37920 aagtaaaaga aataaataaa aaaattgttt aaaataagta ataaataaat ttaaaaaata 37980 agtaaaataa ataaaaattg tttaggttta ggtcgggtat agtggtttat atttgtaatt 38040 ttagtatttt gggaggttaa ggtaggagga ttgttcgagt ttaggagttt gagattagtt 38100 cgggtaatat agtgggattt tgtttttata aaaaataaaa aattagttag gcggggtggt 38160 atatgtttgt agttttagtt atttgggagt ttgagttggg atttaagagt gggtttagag 38220 tagttttcgg ggtcggtagt tgggttttag tttgagttta ggaagttaag gttgtagtga 38280 gtcgtgatcg ggttattgtt ttttagtttg gacgtgcgat agagtgagat tttgttttaa 38340 aataaaataa aaatcgttta ggttaacggt ttttttgggt ttttattttt ttatgaaggt 38400 tcggtgttaa gtaaaattta tttgaattgt tatgtttgtt ttttgttaat ttttgttagt 38460 ttaattttta gggttttagt taatgaattt aaaatcgata gaaggaaagg gttttttttt 38520 agattttgtt ttgattaggt ttttgtaatt ttgtgataaa ggtttgaagg tttgaatagg 38580 aggatataag gtttgagtga gagagaattt ttttcgttta atcgttttta atttggaata 38640 ttagattttt tttgttttag atttaaattg atatatgcgt tttttttggg tttcgggatt 38700 ggaacgacgt tattggtttt tttgggtttt gggtttttag gtggatatta gagtcgtaat 38760 atgggttttt tcgtgttttt agtttgttga tttattttgt taattttggt atttgttaat 38820 ttttgtaatg aggtgagtta attttttata ataataaatt tttttattta aatatacgta 38880 tatatttttt attggttttg tttttttgga tgattttaat ataattattt tgtgaatata 38940 gtaaaattat tgaattgtag attttaaaaa ggttaacgtt atagtatgtg aattttattt 39000 ttataaagtt attatttaaa tagtaataag aagttggtga gttttgtgta tttttttgta 39060 aataagagta gggatagcgt cgtttttgtt ttcggatgtt tttagttttt agttcgagtt 39120 taggaatatt ttttatgtgt tttttttttt aattttgtag tttaagggtg ggggcggttt 39180 ttagtttggt attttttttg tagtttttta tttttttttt atattagtta atggatatag 39240 aggttttttt atggattttt atttttattt atttattttt atttttttga gatagagttt 39300 tattttgtcg tttaggttgg agtgtagtgg tgtgatttcg gtttattgta attttcgttt 39360 tttggatttg agtgattttt ttgttttagt ttttcgagta attgggatta taggtacgtg 39420 ttattatatt tagttaattt tttgtatttt tattagaggt agggtttttt tatgttggtt 39480 aggttggttt cgaatttttg attttaggtg atttattcgt tttagttttt taaagtgttg 39540 ggattagagg tgtgagttat taagtttagt ttttttatag atttttaaaa gggttttggg 39600 taatatagat tgggatttgt taagttatta aatgattttt ttaaataaag aaggaagtta 39660 taaattttta tttaaaagga gtgggggatg gtaatagaaa tatagttagt tagaagtcgg 39720 aagggtttta tttaatttat ttttaaggtt tttgggtaga agggataagg gaaaatttgt 39780 tttttaaata ttttattcgg tattttattt ttcggatgta agatgtagtt gtgtatagcg 39840 gtagtagtga ggattttggt ttggtaggtt tttatatttt ttgttgaggg ttttaggggt 39900 tagggttgtt taataggatt aagaggaaat gattatagga gtttttagtt gttgggggtg 39960 gttttcgcgg ttttttgggt tatttttggt gaatttattt taaatttgga agaggtttaa 40020 gttttttcgt ttttcgtatt ttaaatttta gttacgttag ttaggagttt tgggggatga 40080 gaaaaaattt aattaagttt tattgtgttg ggtgatatag gatttagaag gagaggggtt 40140 tttggattgt ttaagtttaa tgataatttt agtagttggg tttttaagtt aattagtttt 40200 ttttttttta gtagttttcg gggagtatta cggtgagttg tgaggagtta gtttagtacg 40260 gtatatataa cgtaggggtt ttttcgtatt tttattttat aaatattagg gtttttcggg 40320 ggattagttt tttatttttg agttattttt tttttatcgt ttttttaata aggaatagag 40380 aaggagtttt tattgtttaa ttagatgtag aaattgacgt acgtatagag aggttacgtg 40440 tgatatggtt tggacgttgt tttttttaaa ttttatgttg aaatgtgatt tttgatgttg 40500 gaggtaaggt ttgggggggg tggggtttgg gttatggggg tggatttttt atggatggtt 40560 tggtgttttt tttacggtta taaagttcgg gagatttgat tgttatagag tttgggaggg 40620 ttgggtgagg tggtttatat ttgtaatttt agtattttgg gaggttaagg tgggtggatt 40680 ataaggttag gagtttggga ttagttcgat taatatggtg aaattttatt tttagtaaaa 40740 atataaaaaa attagtcggg cgcggtggta tgcgtttgta attttagtta tttaggaggt 40800 tgaggttgta gtgagtcgag gattgtgtta ttgtatttta gtttggttga tatagcgaga 40860 ttttatttta aaaaaaaaaa gagtttggga gttttttttt tcgttatgtg acgtgttagt 40920 ttttttttta ttttttatta tgaggaaaag ttttttgggg tttttttaga agttaagtag 40980 atgttggtat tatttgtata gtttgtagaa tcgtgagtta aataattttt tagtttcggt 41040 tattttttat agtaatttaa aatggacgaa tataatgtat tagttttttt ttttggattt 41100 tatagtgtgt ttggttgggg ttgtgttttg gggaaatggt aattgcgagg tttttataga 41160 tcgggttcgg gttttaatta tagtcgtatt ttagcgtttt gatattgttg agtggatgtt 41220 taaaaagtat tgttgggtga atgtgcgagt gaatgatgaa gatggaggtg gttgttggtg 41280 ttagggtaag gttttaggag tttggggagg tggtattagg tagtttaggt taacggttaa 41340 ttttggatag ggttaggagg tagttagaat ggttaaggat agttaaggga ttttaggtaa 41400 gtggttttat tttttttagg cgggtaggaa gtaggaatta gattaagggg tgttaggtgg 41460 tagtggtatt tagggggttt gaggagtagg tgtaggttta gtagggttgg tggtgttacg 41520 tgtggggtcg atcgtggttt cgtttattgt ttttattttt tggacgtatg ggtttatggt 41580 ttttaaggtt tttttttgtt tttacgttta tttttttagg ttttattttt agacgttaag 41640 ttattttttt atttttattt ttttcgttgt ttttatattt gagttgattt tttttttgag 41700 ttttggtgaa attttagaga gtttagaggt gtagtttata tttttgcgtt ataaggtttt 41760 tgtagttttt atttttttgg gatattttat tttagagttg ggtgtgtatt tattttattg 41820 gattagaaat tttaggaatg tttattttgt atgtttttgt tttttatttt tcgttcgtta 41880 tttagttcgt ggttgttatg tggttgggtt ttggtagtta tcgtagttgg taatatataa 41940 ttagtatttt tgtgtttagg tttcgtgttg agttttttta gttttatttt cgtttgtttt 42000 taaaatggtt tttgatatgg taattattat tatttatttt ttagataaaa gattatagtt 42060 ttaggagagg aggaatggta ggtttgaggt tacgtggttc gtaataggta aatggattcg 42120 gtagttattt tattttcgag tggggttttt ttttgtttgt agatttcgtt gaggttttag 42180 agtttggagt tagtgagttt ttattgagta taaggatagc ggcggtgtcg gggttggaat 42240 aaggtaggga ggggtttttt aaattatagt tttggttgtg gatttatttt gggatttcgt 42300 tttggttggg aattttgttt tagtttattc gggatatttt tttattttga gttttgtatt 42360 gggttgtgta cggggtttgt tgaatgagtg agggtaggag ggatggtgag tagggtggaa 42420 agcgattatg gtgggtaggt ttttgttgga agtttgaaat atttttggcg agtaggaaaa 42480 tattagggga agaggttata gtttttagaa gggttcgttg gggattgttt tgtagttttt 42540 ttatcgggat aggtagaaaa tttagttttt ttttagggtg agtttaggaa gtttgtgggg 42600 gtataggttt tagttagggt ggcgcgtggg tttatttagg ggacgttgtc gtggtttaga 42660 gttaggttaa attttatgta ttttgtaaat aattatttat aataaataag gtttatttat 42720 tttttaagaa gagtaaaata ttataggagg tattttttta ttaattaaat acgttatagt 42780 gattttattg cgttattgag ggagggtatt agggtgttcg gtttagagta aattgtggtt 42840 agggggacgg gtatattgtt aaatcggtta gatttttatt tttgaaaatg tgggttaaat 42900 tttttttaat aagttataag gaaatttagt gtgaatttta tgtttttatt attatcggtt 42960 gttttggaag attgggagga ggggttttgt ttttttttta tttttggtta tagggtttga 43020 ggttataatt tggattggga ttttaatttt ttttttgggg aagaggttta tttagggtgt 43080 ttgttaaggt ttagcgtata aatacggaat tcgtttaacg tttgtttcgg tatttttggg 43140 ttttttatat tgggtttttt tatttgattt tttaagtagt gagagtgatg ggatatgggg 43200 cgtttttagg ggagatttgg ggagatggag taagtttttt agtttaaggt gaggtttcga 43260 ggtatggttt atgtagtgat gttttttacg ggaggtttga ggtatgatta ggagtttgga 43320 gatttagtag aggtttgggt atgggatttt cggtacgtag ttagagcgag ggtcgaggtt 43380 gtatggatgt aagtaggtga ttttgtgtta tcgggtgtta tttgtgtcgg gttttgtgta 43440 gtcgttttta ttttattgag ttttagggag gtgaggtaat tattttaggt atatagtttc 43500 gggggtaaag gttggattta ggtgtgtttg attttagaat ttaagaagat aagtagagga 43560 gtttgagttt tttgagatcg tagtgatggt ttagtgtttt aggatggtta ggttggtttt 43620 tgtagtttta gttaatcgtg ttttttttta gttatttagg gttttagcgt tggtttttga 43680 gatttggtat tggttatagg ggtttatttt tggttgtgga tatttagtgt tggttattgg 43740 gatttggtat tggtcgtggg gatttgtttt tggttgtggg gatttagcgt tggtttttga 43800 gatttggtat tggttatggg gattcgtttt tggttgtggg tattcggtgt tggtttttga 43860 gatttggtat tggttatggg ggttcgtttt tggttgtggg tattcggtgt tggtttttga 43920 gatttggtat tggttatgga ggtttgtttt tggttgtggg tattcggtgt tggtttttga 43980 gatttggtat tggtcgtggg ggtttatttt tggttgtagg gatttagtat tgtttatggg 44040 gtttgttttt ggtttcgggg agttagtagt gtttgtgggg tttatatttg gtggtgggga 44100 tttggtgttg gaggattttg atagtaaaat tatagaggcg ataggtaata gtaatttatt 44160 agtatagcgt gtggtttgtt ttagttacgg tatttttttt tattttgtgt ttttttatta 44220 taaagtttag tgtaggtaac gaagttaaga ggtggagaat tcgtaggagg acgtatatta 44280 tatttgtttt tcgtgtggcg tttttgtatt ttgggtggtt gagatttttt gttttttttt 44340 taggtttttt cgtgttaggt ttgcgttgtt ttttttggtt tcggttttta tttattcggt 44400 tttttagtta tagatagtag cgattttttt ttttatttaa tggggttatt gtttagttta 44460 ttattagttt ttagggttgg tagatgatat cggttacggg tagtgttttt ttcggtttta 44520 gtatataagg tataaaagat attattttgt tttaagattt ttttagttac gtggcgtatg 44580 ggaagcggtg tcgggaattt tttagggtag ttttttgttt cgggggagat cgtgtttaaa 44640 ttttcgagga aatgttgttt tttggttttt tttttgaaaa attttttaag gagattttgt 44700 gcggagcgtg tagggagaat ggagattttt gtgagattgt ttcgggatag ttttatagaa 44760 attataaatt atttggataa aagttgaaaa tttgcggtta tataatgttg attatttatt 44820 taaatattcg ttgagtaagt atttatgacg tttgggaatt taggacgtgg atcgataaga 44880 tataattttt atgttcgttt tagtgataga gagagagacg gtattattaa tttcgttcgt 44940 tgggggtttt tttggagggg gcgtgtaggt ttagggttga atttgtttag tggatgtgtt 45000 atttacgttt gcgtattttt tggttttgtg gtggtttttg gaataaaggt tgagagataa 45060 aagataagga tttgggggag ggaggacgtt tatgtatatt ttattgggga tattagtaag 45120 gatgattgtt tagtgattat ttagtgatcg agttatttgg tgtttggagt ttggtattta 45180 tagagtaggg cgggggtagt aggttttgtc gggggtatag gtttgagaag ggagtgttgt 45240 tagttaggtt cgacgggata gagagcgaag ggtttttttt ttgaaggtta tgtagaggtc 45300 ggaggttaat gttagtaatt ttattaacgt tagttttttg agatcgattt agagttgggg 45360 ttttaagagt agttttgggc gtttaggagt taagatttta tagagggtgt tttttatttt 45420 tagtttaggg aaagtgataa atttggagtg tttttgttta tggtttaatt attgaattta 45480 aatgaatgta ttgataaatc gtatttagtg ttatttatag ggaaaaggga gggaaaaaaa 45540 aaaaagaaag agagttaatc gcgtttaggt cggtcggtta gggggaggat agatgggtta 45600 ttatttttgt tattttttag gttttttgta ttgatttttt atttttagta aaattaaggt 45660 ttagtttttt ttcgtagttt cggagtcggt tgggatgaag taatttttgt aggtagatta 45720 ttaggtttat tgtgatggtt ttagtaggga atttagttta ggttatagta gtttaggcgt 45780 ttgtagaagg tttagatttt tgggtgttaa gttttttttt tttgtattcg tttcggggtt 45840 cggtggggtg ggtagtgtgc gatttttagg gttgatgaaa gagaggagga agaggttgag 45900 cggcggcgag tttgaatagt taattttggg aggggttgag gtggggaagg tttttattgt 45960 tgttttatag gtttcggagt aaggttttta tgattttatt agtagttggg taggtatagg 46020 tttaggtgtt gagtgtgtta ggattttcgt tgttttttgg gtgggggcga gagggatttt 46080 tatgggtttg taattagatt cgcgtttttt tagttaattt tttattaaat aaatttatac 46140 gtatagcgga ttgggtatgg tcgttatttt cgggagtttt tttgggaaag ttttttaagg 46200 ttttgttgag tttcgggaat aggtttttat ttgttcggga atcgggttgg tatttaataa 46260 ataaattaaa gttcggcgtc ggaaggtaga attttgggat tagagtttta gttaagggtt 46320 ataagttttt taggaagttt tttttttaaa gagtggttgt gggacgttgg gagtttttag 46380 ggtggttagt ttttaggttt ttttaaagtt taggtggtat cgatgttttg tgttaaggtg 46440 agggttgtag agaggggtcg gcggggagga gtttttatag tttattttgg ttattgattt 46500 tatttttaag tattgaaata aagttttttt tttatatttt cggttaggga gagagggcgg 46560 aagttttaaa tattcggggt gtatgggaaa ggtttatatg tatagaagaa ttagataacg 46620 gaagttgttg gtggtggtga taggtttttt aaaggggttt tgagattttt gatatcggta 46680 gggaagttat atattgtatt aggtttgggg gtagggagaa ggggttttta aggacggggt 46740 tgtttttttt tgtggaagtg tttcgtattg tttgataaga gtagtttgga ttagtcgtgg 46800 tataatagga agttgggaga atacggtggt ttaggaggtt ggttagggtt ggggagtggt 46860 taatttagag attttggttg tttaagtggg tttagggttt tcggggtgaa agtttttgtg 46920 gagtatagtg gatttagtgt tcggaggata gattttaggt ttagataagg tttttttttt 46980 ttttttttga gatagagttt tatttttgtt gtttagattg gagtgtagta gtataatttt 47040 agtttattgt aatttttatt ttttaggttt aagtgatttt tttgttttag tttttcgagt 47100 agttgttatt ataggtacgc gttattatgt tcggattagt tagtattttt agtagagata 47160 gggttttatt atgttggtta ggttggtttc gaatttttga ttttaggtga tttgtttgtt 47220 ttggtttttt gaagtgttgg gattataggt atgagttatt gcgttcggtt aataaggtta 47280 tttttgatat ggaatgttgg tttgattata gtgtttgatg gtttttgttt gtaattatgt 47340 tttcgttttt tattaaagta gggtttttag ggtagaagtc gtattttttt attttagagt 47400 gttttacgtt attttttagg cgtatatagt gggttttttt tatcgtagtt gaattggttt 47460 tattattatt ataatgatag tttatagggg cgggggttag tgggaatata aagtggttaa 47520 tgtaatagtg ttttagttat ttcgatatag aaatggttag gggatagaag gggtaagttg 47580 ggagttagta gtaatttagg tttttagaga cgagtattaa aaaaggcgag ttatattata 47640 ggtttttttt gattatattt tagtttaaaa gagatttaag gagaaataag aattttattt 47700 ttttaataag gattcgtata ttagatgtta agtaaatatt tttttttttt ttttgaaaag 47760 gagtttttgg ggttgtcggg ggagttggtt aaagagaatg atatttatgg aaatatacgt 47820 ggttttatta agttttaagg taaggtggta atgaatggag gaggaaaatt tatagtatta 47880 ttagggaatg gggttttttt ttgttttttt tttttttaac gggttttttt atgtgggatt 47940 taaattaaat tttaatttta ttttgattta gtaggtgttg tttttatagt ttcgaataga 48000 tttgttagaa aattattgtt taatttgttt tcgggtggta tatttttttt taggaaagga 48060 attataaatt tattttagat gagtagagag ttgtttttta aatttttgat taaaatatag 48120 tagattttat atgaaaaagt aaagagagag gggttaggga tgaagtgtag taggttggag 48180 gttgagttag tttttagagt tattgggacg gcgttttagg agtagatggt attgtttata 48240 aagtttttcg tttttttttg ttttgaggtc ggggattatt tcgttggttg tatgatttag 48300 tttttggggt ttttttagta tgaaaagatt ttttgaaagt aggttcgtta gggagatttt 48360 ttagtttttg tttattgata tgtttttgta tggtcgatac gtagtatgtt attgtagaga 48420 agtaaagtat acgtagatta gtttcgttag tagtattttt ttttttcgtt ttttttagga 48480 acgttttgta tatatttaat atatttagga atttagagtt gcgttgtagt agtagttttt 48540 tggattttag tgtcggcgtc gcggggagtt tcggttacgg tatttcgagt attgagatta 48600 tttttagttt ttagttagtc ggttttcggg agtttagagg ggtgataatt tgagcggagt 48660 gattttagag aaagcggtgg ttaattcgaa tttttttttg gtttttttgg aagttaggga 48720 aattttttgc gaaaaggaaa tatgttttaa gaagtttcgg gtagtaggag aatttagtta 48780 tttagtttag ttggttaaat atttataaag agatagttgt gattatataa agttttattt 48840 ttttattttg aggtcgaaaa tttggttttc gcgtggagat cgagtttttc gttatttttt 48900 ttttggggat ttcgttcggt tttgtcggtt tcgggtcggg gtttagggat agcgtggttt 48960 tcggtatcgt tattatggtt attagggttc gtttcgcggt cgcgttattt gagagttttc 49020 gagttagtgg tgtaaggttg ggaagaataa aggagtagga tttattttag tagcggaacg 49080 tcgggttgcg ttggacgcgt cgagagtcgc ggttcgttta tcgggttata tggtttagag 49140 tcgagtagag gattaaaggg gttttgtggt cgcggaataa ggagtttttt agagcgcggg 49200 gtagaggtag ggagggattt cgattgtttg ggaagggagg ttcggtgggg aattgtttta 49260 agggggtagg gcgaggggag taggaggagg gggtaggtag agataggggc gtttagcggt 49320 aggttcggcg tagaagtaat ttgaaggtac gggagggacg ttaaggagtt gttatacgtt 49380 aaaggaaagt gatagggttt ttgggaagag tgagggggag ttgttaggaa gaagagaggg 49440 gaagaggttt ttagggattt ttggttatgt cgtttttgtt tttgtttttg tgtttgttag 49500 aggcggtgtt cgtgaggagt tttttttttt tagttaggtt ttgaaattga tttggatatt 49560 tttttttttt gtgttttgtt tgatattttt gttttttagg tgttttttta tttatttgtt 49620 tagatatcgt tatagttggg tttttaggga gtatggttag ttattttaga aagttattta 49680 gatttgtagt tagggttgga atatagttat ttgggtttgt tttttttatt ttaggtgttt 49740 gttggttggg attatggaag ggagaaggag taggagagga ggggtagggg atgggggcgt 49800 agtttatttt gagttttttt ttcgagagtt tttggattta gatttgattt agtttttgtt 49860 tttttagttt ttttagtttt tgggggattt ggttagtgag ttagtttttt tttttttttt 49920 tttttgtagg tttgggatgt gttgggattt agaggggtat aagtaagggg gtttttagag 49980 gagggagttg atattatagg ggttgggttt ggacgttggg atttgttaga tttattttag 50040 tgttacgatt tttgaattta agtgagttat ttttagtagg ggcgtggtta tttttatatt 50100 aggagagagc gtttgggagt gggttcgttt cgagggtttg ttgggggttg ggagggattt 50160 atttaaatgg aaagaagttt ttggtgatat tttttgaggg ttaggggttg aattttggaa 50220 gttacgtttt taggtagttt ttacgggatt ttatgttgag tgttgattgg gttttatata 50280 tttttatttt ttttatttcg tatttttata cgtggttggg ggtgattgaa gtttcggggt 50340 attcgttata ttggttaaat aggttagtta cgtttagcgg ttttttagtt agtagttatt 50400 ggtatttgat tcgtcgtttt ttatttttta tggttaattt tttttttaag gttttttggt 50460 tttacggttt tttttatttt tatagtgaac ggtcgtgggg agttgttgtt attggttttc 50520 gggcgttagg ttagagtcgg gggagtgttt gggagaagat tgtatgttcg gagtttttgt 50580 ttttatttga atgggaggga ggttggtggt agattagaga tttgggtttt gagttaaata 50640 ttgaaattta aggttttggg tttgttattt aatatttgtg gaatttgatt ttttttattt 50700 ataaaatggg tattattaat attagtcgtt aaaattatag taagatatat acgtttaggt 50760 taggaagtgc ggttatttag aaaatatagt tttttttttt tttaagaagt taattttttt 50820 agtattggga gtgagaagag tttgtttttt ttattgtttg tagtttagtt tagggtattt 50880 ttattattgg tttttaaagg gtagttttag aaatcgttga taaaggatgt tagaaggaat 50940 ttttttttgg ttaggtgtta gggttaatag aaagtttcga ggatgtagtt tttattacgt 51000 ttttgtttcg tgggtttttt ttttttcgtg ggtagaattt tttttttttg gttttttttt 51060 tcgaattttt ttttttttgt ttttggtttt aatttgtttt ttagtttttt ggttttttag 51120 gtttttttta gggtttaaga ttttgttttt ttttaagttt agtttttttt ttttttttgt 51180 ttttggattt ttgagttggg aggttagtat tttgggtgtt ttgttgaggt ggtcgttttt 51240 tttgtagtgg ttttttttgt tgttattaaa tgagggtttt tagagtatag agaaggtatt 51300 ttcggtttgg ggttgtattt tttatataaa gtttttgttt tttagtattt tttaaagttt 51360 tttatcgttt agtatatatt tagtatttag gtagagtagt tttagagttt tttcggttgg 51420 ttttcggttt aattttttag tagaaacggt atatgggtta tagacgtaat tttatatttt 51480 ttagtattta taataaaaaa tgtaagaata agttaggtat agtggtttac gtttgttata 51540 ttagtatttt gggaggttga ggtgggtaga ttatttgagg ttaggagttt aaaattagtt 51600 tggttaatat ggtaaaattt tgtttttatt aaaaatataa aaattagtta ggtatggtag 51660 tagttatttg taattttagt tatttgggag gttgaggtag gagaatcgtt taaatttggg 51720 aggtaaaggt tgtagtgagt cgagatcgtg ttattgtatt ttagtttggg taatagtgtg 51780 agattttata tttaaaaaaa aaaagaaaag aaaagaaaaa ggaaattatt aaaaaatgta 51840 agaataggtg atattaattt taatattatt tatttaatag agtttaaaat attattaatt 51900 taatatgtaa ttaatgtaaa aatgatagat atttgatatt tttttttttt ttttttgtta 51960 ggattttgaa atttagagtg tattttatat atacggtatt tttttatttg gaattattat 52020 attttaggtg tttaaatggt ttcgtgtagt tagtggttat tatgttggat agtgtagttc 52080 ggagagtttt aatttttttt tttttttttg gttgtcgggg aatagagttt tgttttgtta 52140 tttaggttgg agcgtaatgg cgtgattttg gtttattgta attttcgttt tttgagttta 52200 agtaattttt tcgttttagt tttttaagta gttgggatta taggcgtata ttattatgtt 52260 cggcggttat tttttgtatt tttagtagag atggggtttt attatgttgg ttaggttggt 52320 tttaaattat agattttaat tgattcgttc gttttagttt tttgaagtgt tgagattata 52380 cgcgtgagtt attacgttta ttttcggata gttttaattt gattttagga taatattagg 52440 ttattagaga gttgttgatt tggattatat tatgatttga attttttaga ttattttcgg 52500 tattatgttt ataagttata tttagaggat aataggatat agtttggtga aatatatagc 52560 ggtatttttt ataagatatt ggtgaggtta tagattttat tattagtgtt attcgtttgg 52620 ggatatttta tttttagaaa atgtagagtt ttttttaaga aatgaatgtg gttaggtgtg 52680 ttggtttata tttgttattt tagtattttg ggaggttaag gcgagtatat tgtttgaggt 52740 taggagttta agattagttt gattaatatg gtgaaattta gttattatta aaaatataaa 52800 aattcgttag gcgtggtagt gtgtgtttgt agttttagtt atttaggagg ttgaggtagg 52860 agaatcgttt gaattcggga ggaggaggtt gcggtgagtt gagattacgt tattgtattt 52920 tagtttgggc gatagagcga gatttcgttt taaaaaataa ataaaaaaag aaatgaatgt 52980 tttaggtata cgttaagtat tttttagacg attttaaaga tattaattat tgtgattgac 53040 gacgattttt tttttttttt gggtgtgttt gttttgtttt tttagtttat aggtgtttag 53100 gatttaaagg tagttcgtta taggttatgg gatttggttg gtttaaaagg gagagtgagg 53160 ttattggaat ttttttagga gtgagtttga agtttggaat gttttttggt ggagggtttt 53220 gaagttagga ggcgatgtag acgtgggggt tgagatatta tttggggtta tttgtaaaga 53280 gggatattta ggtagtgatt ttaaggaaag agtaagggga ggagagggcg gtatatttac 53340 gtttttttaa tttttgttcg ttcggaggtt tacgtatttt atacgtcggt tttttcgtat 53400 ggatattttt ttaataagta atttatcgtg tttatgttta tttattttaa agttatatag 53460 aattgtattt attaaaaatg aatttatgga gatagaaagt attttggtgg ttgttaaggg 53520 ttggagaggg cgaatgggga gtgagttttt tatggatacg gggttttttt ttggggtgat 53580 gaaaaagttt tggcgttaga tagtgttgat ggttgtacga tattgtgaat gtatttagtg 53640 ttattaatgg taaattttat gttttgtgta ttttagtata ataaaaaaat atatatttaa 53700 agtaatagaa tttaacgtgt tttttttttt ttttgagtta gtttgttttt ttgttttata 53760 ttttaaaatt agaagggttt tgagatatat tataggtttt tagggtaggt tgaataattt 53820 ttttttttta aattgtgtta ttttatgtgg taatagggat tttgtagatg taattgaaga 53880 tgttgagatg aagagattat ttaggtgggt tttaaattat aagcgttttt taagagggag 53940 gtaggttagg tgtgatggtt tatggttgta attttagtat tttgggaggt tgaggtaggt 54000 agattatttg aggttaggag tttaagatta gtttggttaa tatggtaaaa ttttgttttt 54060 attaaaaata taaaaattag ttaggtgtag tagtatatgt ttgtaatttt agttattcgg 54120 gaagttgagg taggagaatc gtttgaattt aggaggcgga ggttgtagtg agttaagatt 54180 gtgttattgt attttagttt gggtgatttc gttttaaaaa aaaaaaagag gaaggtagag 54240 ggagatttga ttgtagagaa ggaggaggtt gtaggaggat ggaggtagag gttggaggga 54300 tgtagtcgta agttaaggaa ttttagtaga gttttttatt taaagttgga agaggtagga 54360 atggattttg ttaatatttt gattttagtt cggtgagatt gatcggtttt tgatttttag 54420 tattgtaaag gaaggagttt ttgttgtttt aagttattga gtttgtgata agtagttata 54480 gcggtaatag gaagcgaatg tagtttttag tttatttttt cgtttatagt aatataggcg 54540 tttttttgtg tagaattttg ttaggtagtt agtgagcggg ataggatttt ttttcgtttt 54600 tattcggggt tttgtgttgg attttttaag gttgttgttt ttgagatagt gaatttttta 54660 tatttataga gatttatttt aaagttgaga aagtgttttt tttaaggggc gttagaaaga 54720 aggttttaag gtgtttttgt tatatgttta tttgtttgtg ggtaatattt atagtttttt 54780 ttcgtgattt atttaataga agggttatag gggagggagt attattggtt agtttatttt 54840 atagtaaggt tttattttgg aagttatagg ggatagttgg gatttttatt tttaatttag 54900 ttaattggga gaagagttta gaatagtttt ggaggttgat atttgttagg aagtgtggtg 54960 atatttacgt gttgttgaaa tatatagtaa tatagtagta gagaggaggg gatgtggttt 55020 tatagttttt tttttattta tttagtacgt acgtatatat atatatacgt gcgtgtatat 55080 atgtattaat ttttagtttt taggttttgt attttgtttt tgttaagttt ttcggttatt 55140 attaagttag gttgtgagta tagagtttag tttttttgtt aatttttttt taatttattt 55200 tgggtaatat tttaatggga tgtagtagat gttttttatt aaatgttaag agtaatattt 55260 ttttttattt tttgtgagtt ggcggtcgcg tttttgtatg ggggtgcgga ggaaagggtt 55320 ggggagtagg aatgtggttt tgagggttgg tatgtatttg tagttgtgac gtttcgaggt 55380 agtttatatt tttatttata gattaatttt gagaaggggt tgggagtatt tatagttttt 55440 gttatttttg ggttggtagg ttggggaaat tttgagtagt tcgagtgaag gtcgttttta 55500 ggtaggtatg gtgggataga ggggtttttg tatatttttt gtgaggtagc gtagttgttg 55560 ggttgtttta gtatatttgg gtgatatgtt ttttttttgg ttttttttta tttggtttgg 55620 gagaacgttt aggatgtttt aattttaaaa ataagtaaat tttttttttt tgatttattt 55680 atttttttaa attgtgaatt ttttttttgt ttgaatagtt taatttttta aagtaggttt 55740 atattacggt ttttagtttt ttatcgttta tttatttttt agttcgagtt atttggtgtt 55800 cgttcgtttt attattaatt tagtttttga aaaaattttt atggttagta tttagtttta 55860 ttttatttga tttcgagggt agtgtttgat acgtattagt tggttttttt tttttttttt 55920 tttttttcgt attttttagt gttggggttt agatagtttt taagggtttt ttcgtttttt 55980 gatttagttt tttggagtga ttatattttc gttttagttt tttagtttag ttgttttttt 56040 atattttgtt ttaggttttt tttttggaat attgtttgtt tttagagatt taagttttta 56100 ttttttatat tttttttttc gatttttagt ttttttatta aagttttatt ggttgttttt 56160 tttcggtgtt ttaaattagt ttttttttgt ttagatttta taaggttagt ttttatttta 56220 tgattgtttt tttggattat tgggattatt ttttattaat atttattttt tatttcgttt 56280 ttttttgttt atgtagggtt ttgttggagg atttttttcg ttttattatt ttttttttta 56340 aatagttttt taggtttttt tgttaaagtt gaaatttttt ttttgtattc gaggattttt 56400 gtaatttggt taatttattt ttaagtttga atttttattt ttgtttaagg agtttacgtt 56460 ttttagttag gttttattgt ttcgtaaatt ttatttaaaa ttttttttgg taaatgttat 56520 tatttttagg aagttttttt gatatttttt attatatgtg atttttattt ttagagttag 56580 attttgattt ggagattttg atttttattt atttttgttt tttttgagtt ttttaggttg 56640 taggttttag tttatgtttg tgggtttttg tagtaggagg gtttattttt atttttttaa 56700 gaagtgttcg ttttattttt cgttaagttg taatttttta taagtaggta tttttaatat 56760 gtttttttat tttttttttt tttttttttt ttttttgaga cggagtttgg ttttgttgtt 56820 taggttggag tgtagtggcg cgattttagt ttattgtaat ttttattttt taggttttaa 56880 gtgatttttt tgttatagtt tttttcgtag ttgggattat aagtatgcgt cgttacgtta 56940 agttaatttt tttttgtatt tttagtagag atagggtttt attatgttgg ttaggttggt 57000 tttaaatttt tggtttgaag tgattcgtcg attttagttt tttaaagtgt tgggattata 57060 ggcgtgagtt attgtattta gtttaatatg tttttttata ttttttttga aaagttatta 57120 ttatattaat agtgtgtttt ataaattgat aataatttaa aatgtgattt attattaaaa 57180 gtgtgatttt atttttaaat aatattgttg gttgtggttt gtagttagtt ttattatttt 57240 cgtgtgatga ttattttgta gattagtaat ggttttaggt ttatatttaa tttaattatt 57300 ttgttttttt aattttattt ttttttgagt taatattaag tgtgttttag agttgtaaat 57360 ttatggttga tataaaatta ggatttttaa tatttaatat aaagtaatcg ggttttgtat 57420 tggttttaat agtaattata aattacgttt gttttttgta ttgggtatat tgtatttagt 57480 ttataatatg tgtttttgtt ttttttattt tttttattaa gatggtatat aggtttaaat 57540 ttgttttttg ggagtaattg attttttttt ggaagatgtg agtagttttt atattatatt 57600 taagaagata ttgttataag attttatatt ttttatttta gtttttaagg gtttatttat 57660 ttttttaaaa atttatttgt tttgttataa tatgtgtttt ttttttttta tttgtttttt 57720 taagatatag ttttattttg ttgtttagat tggaatgtaa tggtatgatt ttagtttatt 57780 gtaattttcg tttcgtgggt ttaagtaatt tttttgtttt agttttttaa gtagttggga 57840 ttataggtgt gtattattat attcggttaa tttttgtatt tttagtagag acggggtttt 57900 attatgttgg ttaggttggt tttgaatttt cgattttagg tgatttattt gtttcggttt 57960 ttcgaagtgt cgggattata ggcgtgagtt atcgtattcg gtttataata tgtgttttta 58020 tttttttttt tttttttatt aagatagtat acgggtttta agtttttttt tttttttttt 58080 tttttttaag attagttggt tgggtgtagt ggtttatgtt tgtaatttta ttattttggg 58140 aggtcgaggt aggtagatta cgaggttagg agtttgagat tagtttggtt aatatagtga 58200 aattttgttt ttattaaaaa tataaaaaat tagttaggcg tggtggtggg tgtttgtaat 58260 tttagttatt cgggaggttg aggtagggga atcgtttgaa ttcgggaggc ggaggttaga 58320 gtgagtcgag atcgtgttat tgtattttag tttaggtaat agtgtaagat tttgatttaa 58380 aaaaaataaa ataagtggga agaggggaga tagtggaata aggagtttaa tttgtaattg 58440 attgtgaata attaattgag ataatttatt attttcggat tagttacggg ttttattttt 58500 tatttgtttt tttgagttac gttttttagt gaaattttat acgtatgtga ttaaatttgt 58560 tttttttttt attaatttat tttgagtgag tttaatttat agatttttaa atattgaatt 58620 taagagggta gaggaaatgt attttttttt cgttataaaa atattttatt tttttattgt 58680 agtgtcgttt gttttattta tagtcggtaa tttggatttc gttttttaaa gtttatgaaa 58740 gtaggataga ttgtttgtag gatgttttcg ttataaaagg agggttaggt ttggtaggag 58800 gaaagaaacg gaagtggtaa acgtttattt tttgcgttag atagaggtat taggtgttta 58860 ttgttttggg gagtaaatat ttttaaaaac ggaaagaaaa atttttagtt ttattggggt 58920 gtaaaaagtt atgatttttt tcgtggttaa atggttgggt ggtttgggag ataagcggta 58980 gttattttga agtttagttt atttgtttgt aaatggaggg taatgaaatt atttgttgta 59040 tgggtgtttg ataggttgtt gtttaaattt tttgtttttt tttatggggt tttggggaag 59100 attatatgag ttagtaatat aaaagtattt tgaaaattat acgaagtgtt taagtatggg 59160 ggcgttggtt gattttaggt ttgtttttat aagttggtag aaaatttttt agagagggtt 59220 ttgttttttt tttcggggta ggggtcgtag tgttagattt gatggtattg gtggttgttt 59280 aggttatttg gtatgagatt gttgttagtt ttagatttat tttaagtttg ggagggaagt 59340 aggtcggggt gggggttttg aaatttttta tatttttggt agagatatta gggtaggtaa 59400 aagtgttatt tatggtaaat taagaagttt gtttgaattg ggtttaaatt agtttagttt 59460 agaatggagg ttagttttat tttttttttt tagaattagg agtttagtat attagaggtt 59520 gagaaaacgt tggaatagtt tttttatttg tttgtttaga gatagggatt ttaagttatt 59580 ttttttttta gtttatttta taaatttttt gtgttagatt ttttttgttt aggagttata 59640 ggttttattt gggagttatt tagggtttta aggtttttat tatttagttg tttattttat 59700 taggttaggt ttgtaggtat ggagattagt aggatgtggt ttaaatttgg ttgtacgttg 59760 attagttgag tgattttggg tttatttttt aatttttggg aggtaatgtt tttttatttg 59820 taaaaagggg aaagggttta gcgaggagag tgataagtaa aggagatggt atttgtgtag 59880 acggtattgt gcgggcgttt agcggatgat tacgcgttat ttttttgttt tttttttttg 59940 tttttgtggg agcgtgggta gtagggagtt aagaggaagg gagtagttgt tcgtttggga 60000 cgtaggtcgt tttgaattgg aagagaaaaa ggaataagta gtagttgttt attgataagt 60060 tttatgtatt tgtgttttaa aattttaaag gtgtatttga aagatttttt gggtaaattt 60120 ttttttatag atatacgaaa gttaggtgta gtggtttacg tttgtaattt taatattttg 60180 ggaggcgaag gtaggcggat tatttgaagt cgggagttcg agattagttt ggttaatttg 60240 gtgaaatttt atttttatta aaaatataaa aattcgtcgg gcgtggtggt gggcgtttat 60300 aattttagtt atttaggagg ttgaggtagg agattcgttt gaattcgaga ggtggaggtt 60360 gtagtgagtt aagattgtgt tattgtattt tagtttaggt gacggagcga gattttattt 60420 taaataaaaa taaatttaaa aaaaaggtat atgaaaaagg taaaatgtta tgagtgtttt 60480 gtcgtaatgt gttagttata aatgggaatt ggaggatttt ttaagttatt ttttttttta 60540 tttttttttt ttttgtatat gtattaatag ttttttgggt gttggtagta ttaggggatt 60600 tggggtgttt tataggtttt gtttgtttag attttagagt taaggaggag atataaaagt 60660 taaaataggg tggtaagtgg aataaatggg gattagatgg ggtaatttgg tagtattcgg 60720 taaggttttt tttaatgagt ttttaaagag gtttagtttt taggggaagg aggcgtttta 60780 ggtagcgggg gtttgtagag gcgaaggttt agggcggggt ttttagggaa gtcgtttagg 60840 atgttcgaaa ggaggggagt aatttacgag tttggtgata gggtcggtta taaagtgtta 60900 tgaagtatta attaggttgt ttattagttt ttaggataga aagattatag tagttaaggt 60960 gtggggattt gtttatttga tttttattta gtttagaaaa tgattgtttt agggttatag 61020 gtaatagttt aagttttgta agttgttggt tatagggtgt agttgcggta aggtggggac 61080 gtttattagt taagtttttt aggatttttg ggttgtcgga tatgtttgta ggacgttacg 61140 ggggtaggtt agattagggg tatttttatt ttttttttta ggttttagtt tttaggttag 61200 agtgtttttt ggtttttggg gtttttaggg ttgtagatag atagggagag gtttgtgtta 61260 tggtgggtta tttggttttt gtaggaagtg gttagaggtt ttagtatttg gatatagtag 61320 ttattttttt aatttttgtt aatgttgttg ttgttcgggg tttatttttt ttaatttttt 61380 tttttaatta gggaggaaag tattttggag taggaattgg gttatttagt ttgatatttt 61440 agtatgattt tgtatgattt tgggttagtt atttaatttt tttgggtttt tattttttta 61500 tttgtaaatt aggtagataa ttttttaaag ttttttttag ttatagaatt ttaagtgtta 61560 aaataaaaaa aatttataaa aaggaaatat gtgtttagtt tatattttcg tttttatttg 61620 ttaaaagggg aaatggattt gttacggggt tttttttttt taaatagata tgggagattt 61680 tttttatgat tgtagaattg gagtagttta gaggagttta gaatttttta gagtttgaga 61740 tttatagggg aatttatttt aattttttcg ggatagaagt attgttgttt aatggtattt 61800 aatttttatt attgttgtag taaatgatta tatatttgtg atgttaaata atatagatta 61860 gttttatatt ttattttatt aggttatagg gaaggtgttt atagggttgc gtattttttc 61920 gaggttgtag gggagattgc gtttttttgt attttttgtt tatttgtatt ttttggtttg 61980 tggttttttt ttttttttta agtttttttt attgtatttt ttagatggtt tattgcgttt 62040 ttaaaaattt ttgtgatgat agcgggttcg tgtggattat ttaggattat ttttttattt 62100 taagattagt tgattagtga ttttagttgg ttttgttatg ttatttaacg tagttttagg 62160 tgttggggat taggatgtgt ttaattttgg gagttattat tttgttaatt ttaagatata 62220 ggttttggag ggagatgaag ggtaggatta taggtttagg aggttgtttg cgtgggttcg 62280 aattttggtt ttattattaa ggaattgggg gagtatatta tttgtaaaat gggggtcggc 62340 ggggaattag ttttttggtt gttagcgtag agtgaggtag tgtgtgtagt gtttggagta 62400 gtttcgtgag tatttgtttt tttttcgtta aatttataag aattgatttc ggtttaacgg 62460 tttttttaaa tttttagttt ttttcggtta taaggttagg agtatttttt tgtagggtta 62520 tttaagtttt tagttttttt gaaagtttcg gtttatacga tgttggaagt agatgtgtcg 62580 tgggttgttt atttatgtat ggttatcgga gaggttcgga tgatgtcgtt tttaatgggt 62640 gtatagtgta gggtagggtt aggtattaat aattagttat agttattagc gtaagtaagg 62700 ggtttttatt gttatttttg gtttggggtt agggagaagt ttcgggaggt atttgatttt 62760 tttataggga gtggggttat aggagaatgt attcgaaagg ggttgggggg tagtagaaag 62820 ttttttttag aaattttatt tttggttcgt gatagatgat ttttttaggt tattattggg 62880 gtttatttgg gtttttgtag tatggagttt ggttatttta gaaggatgat tgggtaggtt 62940 agggttattg gcgatggtga cggtaggttt ttttgaggtt tttttattag aagtattagg 63000 aggttagagt agtcgataag tttttatttg gtttttgagg ggtagaaggt tttgagtagt 63060 tttttgattt ttcgaggttt ttttatttta ttgagagatt ttcgagagta ttgagagtta 63120 ttttttggtt ttttcgtgag agagttggtt atataaaggt agttatatat ttagtaagat 63180 gaatttataa tttttgagtt taggtttatt tcggtttttt tatagggagt ttttgggggc 63240 gtggggtggg ggtgtagaag ggaggggtcg gtgttttatt tttgggaatt aggttatgag 63300 ttttggattt aggttaaatt atagaggttt tatttttttt taggtttttt gttttttaat 63360 tatttttgta tagggtattt tttttttttt cgtagggttt tattggggtg gggtgaggag 63420 gagttataga attatagtag ttgttatacg ggggtgttaa ggtagggatg ttgatgttaa 63480 tcgaatgggt acgggaaggt agagtaggag gtcggcgttt tgggtttggt taggttgtgt 63540 gattttaggg aatttatttt atttttttcg gtttttagtt ttttttattg taaatcgagg 63600 gagtgaggtt aggtgatttg tataatcgcg tgaatttgtg ttttgtattt tttatttatt 63660 attttaaata atgtttttaa attttagttt tttaatgttt cggtattttt ttgtttgaga 63720 aatatttacg gttgtttttt atgttgtgtt ttaaatatag gtattttggt ttttttttgg 63780 gtgtttttat tagggttaga atgggtagtt tattttgtag gaatttttaa ggatttttag 63840 ttatttttag gatgggggtt ggttgttcgg aagcggtttt tgtttatttt cgtcgtagtt 63900 tttattacga ggttagtgta gtaaaatagg aggtgtaggt ggtcggggtt aggggttagg 63960 ttattttttt tagcggggta ggagaggggc gagaaaagtt ggatattgat tattttaggt 64020 tgagggtttg cgtggaggag ggggtttatg gtaaaggaag tgggaggatg ggaaggagtt 64080 tttgttggat atttttattt cgttggtttt agtttcgttt tcgttttatt tgcggggaga 64140 aagtgaggtt ttttgttttg ttaaatttta gtaatgaatt ttatatttat tttatttttt 64200 gtttattgga aatttttttt ttattttttg gattcgtttt gaatagttgg gttgtagaag 64260 tcggtggaat gaaatatgta gggtggttta gaggggattg tgtcgaatag cgttgtgttt 64320 tcgtttattt ttttttttga agataaggtt tttttgtttt tgtttttttt ttgggaaagt 64380 tggagagggg gttgaggaaa tgggatttat tattaatttt ttcgtgtacg ttggttttta 64440 gtaggtattt ttatattttt taattaggtt cgtagggtgg aaaggtagtc gtcgagttta 64500 atttaatttt tatttagtcg tggaagttag tgtggatggt aaagtattta tgtataaata 64560 tatatacgag gttgaggtta agagaatacg cgtttagttt ttttttggtt ttttagtaac 64620 gtttttatgt tttagttttg ttttaagttt taaacggtgt aaggtttttt taggtggagg 64680 aatggaagtt tttaagaagt tcgtgtttta gggattatat agaggtaggg tttaggagta 64740 aaggttttta gatttcgtag tgcggcgttg gtaagtttgc gttgttgtat ttatattgtt 64800 ttgggatgaa ggcgatatgt tgattttttt taggtggttg taggatagtt aggaggaggt 64860 gagatgttag ttaaaggtag ttatagataa tagtattacg gattattaga aacgttattt 64920 tcgtgttaaa gcgttcgttt tttttagttg ttttattttg tgttaatatt ttttgggagt 64980 gatatgtgtg agattgggtt gtgttgatga gtgattattg gtatttttag attatattaa 65040 ggaggggtta ttttgttgtt aattaggtgt agggtaggcg gtattggggt acgacgattc 65100 gttcggtatg gttgttttat tttttttttt gtttgagtat aggttggtag gtttagagga 65160 gaggaggaaa tagagttatt atggggggcg tgtttagggg tgagttattt taagaagtta 65220 tagaattagg gtatgggaga tattgtttag ttttgttatt aatttgtcgt gcgaagttgg 65280 ttaagttatt gtattttttt gggttttagg ttttgtaatt agagggttgg tcgaagaggt 65340 aaatgatagt ggttagggat gggggtattg aagttagatt tttcgtattc ggattttttt 65400 tttgttatgt ttagagggag gtttgggtag gttatttaat atttttgggt tgtgggtttt 65460 ttatcggtga aatgggaata ataatagaat taattttata gtgttgttgg gaggattaaa 65520 ggggatattt attttaggta aagagttttt aagatagttc ggggttttta ggaagttttt 65580 gttattatta tcggatatta ttatttttgt tacggttgtt agggtttcgt ttagtatcgg 65640 tagtttgatg tcggtagagg aagggtgagg tttttgtttt tttgtagcgt tttttttttt 65700 tttttttttt tagttatggt aataatagtt gaagtttatt tttagtttta gcgattggtt 65760 atttttttga attaaggatt gaaggtttta ggtttgttat ttaaggttta ggtgtaagag 65820 gggtgagtta tcggtttttg tttttattat atttaggttt ttatacgttt ttttaaatag 65880 gtttttgttt tacgtgtaag agaagatgtt aatttttacg tttggggcgg gggtgtttat 65940 aaatgttttg gacgtgagtt ttgacggggg ttatggtgta ggttttgtta gggtattttt 66000 aattataggg gattatttgt agtttataga gggttttttg taggttaatg ggattttgtt 66060 attttggttg ttattttgtt tagttatttg gtaaggaaaa taggttgtag atttagaggt 66120 agtacgggtt tatatgttag cgagataata taataaggga aggatgtgta ggacgaggga 66180 gttatggaga ttttatcgta gttttagtta tttattagta gattttgtgc ggacgtcggg 66240 taggttattt tattaatttt taggatgttt ttgtaggttt tgcgggtgga tagggtgaac 66300 ggaggtataa ggagggtaag tttgataggg gttggggttg ggtttggagt tagaatttta 66360 gttagttttg ttatcgtatt ttagggtatt tttcgtagat agtaggttaa agtaaggttg 66420 tttagattaa aggggaaggg gttttgtttt ttttattaag ggttttttgg agattttaat 66480 atagattttt agtttataga tattaaattt agggtttttg agaagtgaga aatgtgaaaa 66540 acgtatagaa tagttgtagt ttagcgtttt taatacgtta gatttatata ggtatatata 66600 gcgtttttgt agaggttaga aagttttgtg ttgggaagtt tttcgatcgg gggaggtttt 66660 atagtaagtt tttttttttg tttatttatt aacgggcgga aggttttaat taggattata 66720 tgggaagggt tagcgggagg ggtagagagg gaaaatgaat aggtaatatt aagtgtttgg 66780 ggcggggggc gtaggggata tttaggaggg gagggtaggg gtgtattttt tatttaattt 66840 atagggaacg ggggttcggg aggtgtagga gaaggtttcg gtatttttat tttttttttt 66900 ttgtagattt atttatagtt tgtttacggg tagttagatt tagttatagg ttagacgttc 66960 gttttagttt tatttttttg gtttattgaa agtaagttag gatagtgagg gggacgatgt 67020 tgttattttc ggtatggtta tgttgggttt cggggtgggt gggaacgtgg ttggggcgtt 67080 attttttttg gtcgttatag gtataaaagt tttttcgtgt tttagtgtta tatgtgggtt 67140 ttttttttgt tgttttaata ggacggatat ttaagtagat tttgttggtc ggggggggtt 67200 ttcgtattta gttttatttt gatttagcga attttttttt tgttttttgg ggtaggagtt 67260 attaggtcgg gttttaggta atggttagtg aaggggttgt atggaggggt tttttaggtt 67320 tataggaagg gaggtttttt ttttttgtaa cgtggttgta gtattttgtg atcgagaggg 67380 atattacggt tggagatggt gggatggagg attttttata gtattttcga tgtttagaat 67440 attttatttt gtataaaaaa gttttaaatt tttttgaggg ttgaagttat ttagagttgg 67500 ggtttttgtt ttttaggtta aaagtatttt gtcggagtag ttgagagtat agcgggaggg 67560 gaggggtagg agggaatagt ttcgttacgg cgatagggga ttttttgatt ttaagagggt 67620 ttgtagatat tattatttat ttttagtttt gaattgtttt ttgttaaggg gttagaaatt 67680 tttgggaggg ggattatagg gggtttcgtt tatgagaata gtgattgtgg ttaggttata 67740 gtttataagt tagtaatttt gtttagtcgt cgcggtggtt tttttttgat ggtttttaga 67800 aaaagcgttt tattttttgt tattagtgtt ttgaaattta agaatatttt ttaaatagta 67860 attgtagtaa aagttaatgt tgcgtgagtg tcgtaggtat tatttttagg gttttatata 67920 tttttcgttt agtttttata aaaattttat tttatttttt ttttcgtttt ttttttttaa 67980 tagtttagaa aacgagtacg gaagggttaa gttggtttga ggaggggttg gtggaatagt 68040 ttgagggttt agtttttaag aattttatat tgtaaaggga atttttgggt tagggagtag 68100 ggtatagttt ttattttttt attttcgttt ttagtattag gtttgatata gacggggttt 68160 cggttatgaa taaatgaata agtgaatgag agtttgttga gggaagaagg tgatagggat 68220 aagggagaaa taaagtagtt aatgtcgtcg tgatgatgac gatgttaacg gtagtattga 68280 tatgtgggtt tttgttatgt taggatcgtt ttaagtattt tgttttatga atatttttgt 68340 tttttattat gtttcgagtg gatattttta ttagtttatt ttatagaggg gaatatagtt 68400 gagcgtattg gttaaggtta tgttgttagg aaaggttaga gtttaggtag tatgtggttt 68460 tttagtcggg ttttggttta tacggtttta taggtagttt tatgaaatac gtagagagag 68520 tatgtgaggg gtttttttgt tgttttttat ttttagttgg ggtttatttt ttgttgaaat 68580 ttttttaatt tgtttttaag tttcgttagt tacgaaatat ttttttgaat atttagtatt 68640 atttttttat ggttatttgg ttttattttt ttatagggta agttttgggc gaaaagtaga 68700 aaggatgaaa atttttgaga gaggtgataa cgtggtaatt tttttttttt tttttttttt 68760 tttgagatag tattttattt tcgttgttta ggttggaatg tagtggtacg attttggttt 68820 attgtaattt ttatttttcg ggtttaagtt atttttttgt tttagttttt tgaggagttg 68880 ggagtatagg tatgtgttat tatattaggt taatttttgt gtttttttgt agagatggag 68940 tttcgttatg ttgtttaggt tggttttaaa ttcgtgggtt taagtaattt gtttgtttta 69000 gttttttggg attatagacg tgaattatcg tgtttggttg aggtggtttt tatataaagt 69060 agagaaaatt atttttagtt taaaataaat taataagtat tgagtgttta tgtagaaaaa 69120 gattagaagg aaacgtgaat atgttaatag tgtttgtttg gaggacgtaa ttattattga 69180 ttattttttt tatatttttt aatttaatta ttttgttata agtaggtgtg atttttaaaa 69240 ttataaaaga taaacgttgg ttttttgttt gtgttttgtt ttttgagata gggttttatt 69300 ttgttattta ggagttggag tatagtggtg tggttatagt ttattgtagt tttaaatttt 69360 taatttaagt aattttttta tttgagtttt ttgaggagtt gggattatag gtaagcgtta 69420 ttatttttag tatttttgtt gtttagattg gtttcgaacg tttggtttta agcgattttt 69480 ttatcgtagt tttttaaagt tgggattata ggcgtgagtt attacgttta gtaaagattg 69540 ttttttaatt aggaagatag atgtttttta gtattttttg tttttttttt tttttttttt 69600 tttgatacgg agtattgttt tgttgtttag gttggagtgt agtagtatag tttcggttta 69660 ttgtaatttt tgtttttcgg gtttaagaga tttttttgtt ttagttttta gagtagttgg 69720 gattataagc gtgtattatt atatttggtt aatttttgta tttttagtag agatggggtt 69780 tcgttatgtt gattagtttg gttttgaatt tttgatttta agggatttat tcgttttggt 69840 tttttaaagt gttgggatta tatgcgtgag ttattatttt cggtttgttt tttagtattt 69900 ttaatttttg ttttttggta ttatttggtt aagtagatga aaagttttag tgagttgtta 69960 gtcggtatta ggttggggtt ttttttaggt agttttaagt ggttaggatt tggttttttt 70020 tttagagttg ggtttagaaa ttaagatcgg gaatgcgtga tggttgtttt gcgggttttt 70080 gttatgaggt tatttttttg gttttagtga tcggtcgttg gttgtaggga gtatgtgggt 70140 ttagttaggg tttgtgttaa tatggttttg ttttatttac ggtttagtgg gtttttttat 70200 ttttcgttgt atgataattt taggaaaaat gttaggaggg agggagtcgt tgggggtgtg 70260 ataggagaga ttttttaggg atagatttgt aaaaattgtt ttaaagtttt ttttaaggat 70320 ttttaaggtt tttattgttt tttattgata ggttacggtt cgggtagaga aagttgggga 70380 tggagttggc ggggggaggg tggttagtat tcgtaaggta aggagatgag ttgggagaat 70440 aggggttggg agggtagttt taggttagtt tttgttttta gaattattgt tttttttttt 70500 tggttataaa gtgaggttgg ttagatatag gtttatttta taggttggga ggttgggcgt 70560 gaaagtattg tgtttgtatg gggtatttta tggtgaatat tattagagtt aatttttagg 70620 gtttgttgtt ttatagggaa gttagtgtaa ggcgtttatg gaatttagaa gtatttaaag 70680 gatttgatag ttatgagttg ggaggattta gttttgtagt aggagaaaga gaggtagaga 70740 gataggtttc gtaatatttg ttttattcgt tgtgttgttt tgagtatagt ttattttttt 70800 gtggtttcga gttttagttt tgaggttttt aagatttttt gggttttcgt agtttaggat 70860 gtttatttga aaattaggtt tagttagtag ggtttttttc gttagtttat tattggttag 70920 tttttgttta gtatttttta gtttattatt tttatttgtg taaattttat attagtattt 70980 taagtttttt tttttttagg aaggagattg tttttagatg tgttttttgt tttttttcga 71040 ttaaagttta gaaaatagga attagttttg cgtttttttt ttttatcgaa ttgttggttt 71100 ttttggatgt tttttttgat tttttgttaa tatttttata atataattag tttttagttt 71160 ttttttaaat gtaatcggcg agtacgttgt agtttaggcg gacggtgatg tttttatttt 71220 gtaatttgcg agagttagta tattttttag ttaggtgggt tgtaggagtt agtcgtggcg 71280 agggtaggag gtttgcgtgt tgacggtatc ggtattatta aaattacggt tagattaagg 71340 ttacggttaa cgagtttttt tatttgtaat ttttttttta ttaaggtggt tttagtttta 71400 gtttcggttt tagttttggt tttggtttta ggagttgtag atatattttt aagtttttat 71460 tttaggagtt tggttttata tatatcggag gatacggagt tggggtataa atagttaaga 71520 ataggtatat ttgtaattag gagtaggggg cggagggttg ttgagatgtt tttattttta 71580 tcggttgttt tttttgacgg tttattattt attatatatt gattgtataa ttagggttgt 71640 gatatgtttg ttttttatat tatattatta aatttttaaa tttgttttta atttatatac 71700 gatgaggtaa atttagagtt aataatttgt ttattagttt ttgaatttat gggtggtttt 71760 aatttttttt tttttagttt ttttgggttt atatgagtat tgaggtataa gggaatttta 71820 ttagttggga agtgtgtttt ttttttgttg attttatagt ttttttagtt tgtgtttgaa 71880 gttgttaata tttttttatt tagtattgtt ttttgtagtt tgagttgtcg ttgtgtgatt 71940 tagggttagt gttttaattt ttttggatta tatttgtaag atgaggatgt cgtcgtatag 72000 tttattttaa atggttatta agttgtttgt atagttaata tttgtcgagt ttgtgatacg 72060 attagttttg ttttaatttc gaatgtggta tttttattta gtttgggggt ggaattgtta 72120 gttttttttt ttttggataa ggaagttgaa aggttttaga aggtattaag gttagttgat 72180 ttgttagtag gtatagtgtt tatttgttat ttatagtttt tttttgatcg tttcgtttgt 72240 ttttttagtt gagattttgt gtgtatttga atattttgtt aatggttgaa tttgtattag 72300 ggttattgtg ttagttgggt ttgttaggtt atcgttttcg agttttgttt aaggtagggt 72360 tagtgtttat attttgtttt tttgttagtg ttttatttaa ggttttggaa aggttttgga 72420 gttagagatt cggttaaatt ttggtaatgt tttatatttg ttgtgtgatt atgggttagc 72480 gatttagttt ttttgtgttt ttcgggttgt tgtgagggtt ataggagatg tatagagggt 72540 tttgagtttg gtggttggta tgttgtaaag gttagttacg tggtgtaagg atggtattga 72600 tgataataaa tgaatcgaac gaaaattagg ttaattgggt ttggggaggg gcgttggtta 72660 aatagattcg agtggattag gattttgtat atgatgagta agcgggaata gttttaaata 72720 gtaagtcggg taggtttagg atgatttagt tttgggtgtt gtttagggtt ttttttcggt 72780 ttttttgtcg gtttggtttt tttttgtttt agtttgattg tttttatggg ttttaataag 72840 tttttgatta ggattgaggt agaatagata gggtttaaga ttttgtaggt aggtatagag 72900 tgtggatggt aaaaggagat gttttaggtt ttttgtcgtt tttttttttt cgaaggttga 72960 taatgttaat ttatagaaga agttgttttt ttcggtttcg gattttattt taatatagtg 73020 tatgaggtag ttgtgtttaa ggggtgtgat tatttttgta gatggaattt atttattgtg 73080 tttagtttat tgttagagtt cggaggacgg gggaagtgag gtggggtatt ttttatagtg 73140 aagggaaaat ttagtttagt tatttttttt tgtgttgttt ttggaattta ttttgttatg 73200 gttttatttt aatttagttt tttaaagttt tagagagttt tgtttttttt tttgtatttt 73260 atttcgttta tttgtgttgg gttagttttt tagaagtttc gttttttgtt atttttaggg 73320 tattaaggtt ggttggtggg tttagggatt tttatttttt gatttagttt tagtggttta 73380 ttttatattt atcggtattt ataggtgtgt tttttatttt cggtttttgt ataggcggtt 73440 ttatattttg ggagtttagt tttttttaag gatttacgtt agagtatagg gatttttgtt 73500 tttgattttt ttttagtttt aattacgagt agtttatgtt atagtaattt tttagttgtt 73560 tgtagttgtt tgttaagtta tgataatggt ttttgttttt taatttaatg tttgtatata 73620 gataaatcgt tatattttaa gtagattaga tattattttt tttaggaagt tttttttgat 73680 tgttttagtt ggatagaggt tttttttttt tgtgtttttt taatgtttaa taggtattta 73740 ttgagtattc gtgatatgta aggtatttat aatataagtt agtgtttttt gtttttttag 73800 agggtatatg aataaataaa cggtaagatt ttttaatatt tatttatgtt ttatagaaag 73860 ttatttatag gtatgggagg gttgttttaa ttgcgggtga tagggaggtt tttttaagat 73920 ggtagcgttt tagtaagatt tgaatgaggc ggttaggagg tttagggagg gattttttag 73980 gagggaataa gtgaatattt tttcgtgagg atgagttttt atgttttagg agtagttagg 74040 ttaggggatc ggtgtagtga ataggggttg aggggagtgg ttaggtgacg tagggtttta 74100 taggtcgttt tacgatgagt tagcgtttta agtatagtag atatttaggg aaggtttagg 74160 ttggggagtg atttgaatag attttttatt taggagttta tcggggtttt tgggtttacg 74220 ttgttgcgtt attgtatgtt ttcgggggtt cgggggggta ttttttatat tattattata 74280 ggtagtattt ttgggggagg tgtgttgtgt aggggattcg ttggttattt tgtcgggtaa 74340 attatagggg attgtgtagg ataggcggtt agtttaggag ggataattat ttaagtaggg 74400 gttagagggt attcggattc gggaggagtg tttaattttt taggtttagg taattagagg 74460 tggggggcgg ggtgttgttt tttgatatgg gaggtttggg ggtttggttg tattttttgg 74520 tgtggaggtg ttgggaggtg tggaggtttt tttttgaggt tgggattttt tggttatttt 74580 gatttattgt ttcgatttta ttttttagtt tgagggtatg gtttgaattt atagtcgtat 74640 atattttttt ttgtataggg ttttgcgggg tcggtatagt agtttttttt ttatagatta 74700 ggatgtttag ttttaggagg gttgggattg tttaagatcg tataattagg gttagatata 74760 gttgggttaa ttttgtgatt tttggtttta cgtatagatt ttaagtatat aggtaaaatt 74820 ttgttggttg ggagggttgg ggggtagatg agcggggggt agtttttttt tagtttttta 74880 atatgttagg tttttgggtg ggagggggta taaagatttt atttttttta agagatagag 74940 aaagaggtag tggagggttt ttttttggtt gaggttttag gttttgagtg gtgaatgtaa 75000 ttttatttgg aggttggaag ttaggcggtt ttgggggtgt gcgaggttcg ttagtttagt 75060 tgtagttttt tttatgtaag ggaatttttt ttaggtagcg tttttatgat tagagagggg 75120 gttaggaaga ggtgagggtt gtatttagag tgatattcgg gtgggtttta ttttggggat 75180 acggttatat ttttttttcg gatttttgaa gtttttaggt gcgggttaag ggtttttagt 75240 tgtaggtagg agagggtttt atagttatag atttggggag tttagtttgt aaagtttaga 75300 ggttttcgga ggtcgttggt tcggtttttt gtgtagttgg gtttttttgg gaggtttttt 75360 ttcggtattt ttagttttta gttcgtacga ttttttatag ttgggtttat ttttttaggt 75420 tcgggttata tggtgtaggt tagtggggtt ttgggggagg gtagggcgtt aggaatagtt 75480 tcgggggtgg ggggattgga gtagagttta ttttggtcgt ttgtttattt tgtatgaagg 75540 acgttagatt tttatatgtg gttattcgat ttcgtttaat tatgcgtaag ttttggttat 75600 ttttatttta ttgatgggaa ttaaattggt taaggagaag tttagaattt gagtagagta 75660 ggggtttaag ttttttagga gttttaggta ttttttagtt ttttttttcg agtattgagt 75720 ttatatattt agtgttcgga tgtttattta tttgggggtt cggcgatcgt tagttagtat 75780 ggtttataaa gggtttttgt gtaataggtt ttatttgatt tttttaaaaa tttttcgagg 75840 taggataatg ttatttaatt tattttatag ataaagtaat tgagttataa aatggtttgt 75900 taaaagatat agaggtagaa agattaatag taaagagttt ttttgtgatt ttgattagta 75960 aggtttttag aaaaaagtaa gggatttcga ggtttttata ggaatagagt tttggaggag 76020 aataagagtt tagttttatg ttatttttaa ggggtatttt gaaggttaag gtattgggtt 76080 taagtaggtt ggattgtgtt ttttgtattt tttttatttt ttgaagtttt ttttttttta 76140 tttaggtggg tcgtggaggt gtttataata tataatggaa tagttggtag gttattgggt 76200 tttttattga gttaaggggt tcgattagag gtttaaatag tggtatagaa attatgagtt 76260 tcgttgtaaa ttagtttagg ttttggagtt aagtagtttt gtgtttatag ttagggttag 76320 tcgtttttag ttgtgtggtt tgaggttagt tttttaattt ttttgtgttt cggtgttttt 76380 tttgtagtag taataggaat cgttttttac ggcgatagtg tagatatatt ttatgaagcg 76440 tataaagttt cgagtttagc gtttggagta cgttaggacg tagtaagtgg ttatttatga 76500 tttatgaaat attaataagg tgaggggtgg aatgatagtt tttttgcgtt gtttttaaaa 76560 tggaaataaa tttgtttagc gtttaaagta gtagaaagtg agttaaggat aggtttttag 76620 cgatatgttt tggtagagtg ttttttgttg gttttaggta gggtttaggg cgggcggtta 76680 ttttttagat gagtttatcg ttggtatttg tttttagagt atatgtttgg attttttaga 76740 tttttttttt tttttttttg attttttttt attttgtaat ttttattttt tgttattttt 76800 ttatttattt ttttttttta tttttgttta aaaataaata atggaggtta aatgtgttag 76860 ttggtttttt ggaaaggttt ttttgtagta ggaacgcgac gggggtagtg gaggattgtt 76920 tagcgtaagt tacgtgattt tcgcgcggag tcggggaagg ggaggcgttg agatcgaggg 76980 tgttaggatc gaggtattga gatggggtta ttggataatg gttagggtta gttttcgttt 77040 ttattttaat aggggttttt atatttaggg gttatatttt taaagttttt tggataagag 77100 agataaattt tattataggg ttagaaacgt tgtttttagg tcgttatttg ggtgggggtg 77160 agagatgttt cgtcggtttt taaatattta ttttgtggat aaaattatta aggggaattt 77220 aatgttttta tagtagtttg gttaagatat aggtattagg tcgggcgtag tggtttacgt 77280 ttgtagtttt agtattttgg gaggttgagg cgggcggatc gtttgaggtt aggagttcga 77340 gattagtttg gttaatatgg tgaaatttta tttttattaa aaatataaaa attagttagg 77400 tgtggtggtg tgagtttgta gttttagtta tttaggaggt tgagatagga gaattgtttg 77460 aattttggag gtggaggttg ttatgagtgg atattatatt attgtatttt agtttggatg 77520 atagagcgag taagatagtt ttaagaaaaa aaaagatgta ggtattgttt tagggtttat 77580 aagtataatt tgatttttga tgttggtatt taattttgat gtagatttta gtaggaaaag 77640 ggagacgaat tagaaggttg tggggacgag gggtttatag tagtgtttat tagatttgtt 77700 ttggtaggta taagtgtttt ttggaggttg ttagataagt agagggttta ttttagagat 77760 tttggttttg gagggttggg ttagggttta ggaagttgta tttcggtagg gaatttagag 77820 ttattttgag ttttattttg gaagtaagag ttagggggta gaatagaatc ggaattaaaa 77880 gtttttgtgg gtttagtttt atggggatgg gttcggtttt atggggatgg atttttgtat 77940 tattcgaggt gattattagt tcggtttttc gggattagtt ttgagtgttt tttggggaaa 78000 gcgggatttg tagaggatgg ttttttagga ttcgtttgat tatttatttt tagttcgttt 78060 ttattttagt ttttttgatt tttatttttt atttagaatt ttggagattt ggttttggag 78120 gtttagagat tagaaatgag gggagataag gggagaagtt ttttttttta ttcgttggtt 78180 acgttaatgg gttgattttt taggaagtta tattagttat tgttattgtt ttggtcgttt 78240 cgtttggttt cgaggttggg tgagtaagta tttcgttttg tttgtttttt tatttgagtt 78300 ttttgttgat gttacgagag gtttgattac gcgtttagga ggtataggat agagtttaga 78360 gttgtttaag aatatataag gttgaggttc gggttttgta tttgggaagg gttaggaagg 78420 gttaaaggaa aattttagtt gagtataatg gtttatgttt ggaattttag tattttggta 78480 ggttaaggta ggaggattat ttaagtttag gagttggagt ttagtttggg aaatatagta 78540 agattttatt tttataaaaa aaaattaaaa ttaaaaaatt aattaggtat ggtggtatat 78600 atttgtagtt ttagttattt ggtaggttga gatgggagga ttgttgagtt taggaggtcg 78660 agattatagt gagcgggata ttgggttatt gaattttagt ttgggcgata gagagagatc 78720 gttttaaaaa aaatttttat attttatgga gtttagtaga attttcggtt agggtgtttc 78780 gattgtgaaa tgagcgtggt agttgttaat tttcgagggt gaagatttat ttattagtaa 78840 tttgtatttt ggtacggtga gaggaagtgt ttggggaaag acgtcggtcg aggtagagag 78900 tttagtttaa tttatcgtgg aggagttatt ttagttttaa agagaaagat taataaattt 78960 taggtgaatg gtttaaaagt tatttttgta tacgtagagg gtgtattttg ggatatgtgg 79020 atattttttt ttaggatagg aagtaaaatt agtaggtaga gacgtgagtt tttttgtttt 79080 tgtcggagtt aatttggagt ttttatttcg gtttttaggg aagtatagat ttttattttt 79140 atcgtagtta aaagattttt tgttgatttt tttagtagta tttagtttag ttttgtgggg 79200 agaggcggta gggggaggag atagagaaag atgagttttt ggtagttgtg attgggggga 79260 gagaaatgcg gttttaattt gtttttgttt attttataga cgggcggtgt tttattttaa 79320 aatttagggt agttgaggga ttgaaggaag agggggatat tttttaattg gggttttttt 79380 ttattttatt ttatggcgtt ttatatagga aagagttgga aggtttcggg tttttggtat 79440 ttagttaaag ttttaggtag gggtttagat attgggttgt gttattattt taggtagttc 79500 gggagttagc gacggtagag ttttattttt atttcgatta ttgtatagta tttcgttttt 79560 aggatagttt agtagttagg ttgttttagg gtttaaattt agatatttaa ttgtgggggt 79620 tttaggtaag tggttgaagt tttttgcgtt ttgatttttt aatttggaaa atgggatgat 79680 gaaagtaatt gttgggtagg gtaaggggta agtgaaagtt agcgtttgag agtgatgtgg 79740 ttaggatcgt tgttgtgatt atatattgag tttttttttt ttatttgaga taagggtttt 79800 attgattgtt gttagaaaga tttagattta gaaggattag gaaagtcgtt ttatttataa 79860 ttttagaggg aaggggaggt tttcgtgtta gttggttgtt gtaggggaga gggtgggaga 79920 tagatggggg atagaggagt aggggtagta ggaggaacgg tcggtaggga agttcgtttg 79980 agatttaaag gattgtttat taggaggata gtttaggttt tttttattga gaaagatttt 80040 tttggatagt tgggttgagg atttttaggt tttttgggtg gagtagaatt agttattatt 80100 gaagttatat aggtttgtaa gtataagtgg gggattgttt aggtattttt gttttatagg 80160 ggttaggtat taaggttagg gtggttagag gatatgacgt agtttagtag gggtttcgta 80220 gaattattag ttaagaagat atatgtagaa gtacgtaagt gtttcgagga ggtaaatttt 80280 ttgttggatt gaatatgggg agttgagttt ttaattattg agtcgggttg ttcggttcgt 80340 tttttttttt ttgaatagaa ggtttttaga tagagtagtt aggtaatagt atggttaagt 80400 aggggtttgt attttagttt tgttttgtag tttgattagg ttgtcgtttt tttaggagat 80460 acgggattgg ttagggtttt tttaggttgt tataggaata aggtagggtt gtgatttttt 80520 ttatggttta ggtatttggg ggagggatta tgagttttag tttaggggat agataggaaa 80580 cggatagttc gttttttttt taattacgga gttggttttt tttttatcgt atttttttta 80640 gttatgtttt ttattagaag attatcgtat ttaatgggtg gttttgtagc gatatttagt 80700 ttaatgaagt tatttggtgg gggttttggg ggatgtagtt ttttgaaata tatacgggta 80760 gtgggtgagt cggaggttgc gtggggtttt gttttttggg gatggttagg aggtgtttta 80820 attatttgta attcgagttt atagtgatcg ggatttgttg tttttttatt ttagtttttt 80880 tttattagta ttcgttaagc gttagttagt aggtgtcggt acggtttaag gtaggtttgt 80940 agttagatta gtatcggggg agggatcggg agagagattt ttagagtgga agttatagtt 81000 tttttttttt ttaggttggg taatagatta ttatttttag ttagttttgg ggaaggggga 81060 ggggttagtt gggtcgtagg tatagcgttg gggttttttg aggtggttgt tgttgattac 81120 ggtttttttt ttttttgggt tgggtaatag attattattt tcggtttatt ttagggaagc 81180 gggaggggtt agttggggta taggtatagc gtcggggttt ttgcggcggt tgttgttgat 81240 tacgggtttg ttattttttt tttagttggg ttgttatttc ggttttgaaa gcgttttttt 81300 tagtttttaa ttcgtgttta ggaggtagtc gatattttaa gcgttgttat agtaggaggt 81360 tgggtttgta agtgtgattc gtttggggag gggtagaggg aaagattatt ttcgtttaaa 81420 tagcggtttt tttttttttt tcgggggttt ttatagggtt tttagttttt ttttggttaa 81480 gaggtaagga gaggtaggaa agttttagga atatcggtag agaagagata gggtaggttg 81540 ttagaggaag taggttgtag ggtgtttaag gttttaggtt gggttttggg aggttagggt 81600 atgggtaatt aggaggttta ggtagggaaa tttgtttcgt agggattttg ggagataggg 81660 gagaggggat atgatagtcg ttttttgttg ttttttggtt gtggttttta ggggttttag 81720 tttagattag aagtatttta tgtatcgggt ttcggtttag tttggaagta cggtttatag 81780 atttatatga ttatttgggt agtgattttt aaaaggtttt tcgttattag ttggggagtt 81840 ttcgagggga gggtggtttt gtagagtatt tggagatatt aatgggtcgt gaggaaagga 81900 ggaggcgtgg atatttttac ggttttaaga gaaaattaag gtagagttgg aggttgggcg 81960 tggcggttta tatttgtaat tttagtattt tgggaagtcg aggtgggtag attatttgag 82020 gttaggagtt taagattagt ttggttaata tggtgaaaat cggtttttgt taaaaatata 82080 aaaattagtt tgttatggtg atacgcgttt gtagttttag ttatttagga ggttgaggta 82140 ggagaattgt ttgaatttag gaggtggaga ttgtagtgag ttaagatggt attattgtat 82200 tttagtttgg gtaatagagt aaaattttat tttaagaaaa aaaaagagta gagttggagg 82260 ttaggcggtt tttagagttt gataaggagg tcgtggggtt gggttgtttt ttcggttatt 82320 tgaggggtag ggattggttt agtttgagtt ttagatttat aagaggttga atcggagcgg 82380 gatttcgaga tgaggtaggg ttattttgtt tatatttgtg tttaggtttt aatagttatt 82440 ttttttagga atttagtttg atggtttttt aggttgagag gttgttaagg ggttgtaagg 82500 tgtcgtaacg tgtgagtcgg tgggttttga tgtgtgatag ttcggggtat tttttttatc 82560 gttagggaat aggaatgagg agttttttat ttttagtgtt tggtaggtag gaggtcgtta 82620 ttggattgtg tgtttaggtg ttattagatt tcgagggttt acggatacgg tatatgattt 82680 ttaatgatta acgtttgtgt agtaggtgtt gaggtgtttt aatttcgagt aaggttgggt 82740 ttttggaatt tttttttcgg taggaggatt tgtagttgag gaatttttaa gaaatttttt 82800 ggtagtaaat aaagtatggg gttggacggt ggatttatga gtgtttttat atgaatgcgg 82860 atatagatag aaaagacggt aaatatttgt gaataaaagg aatggttttt gcgtattgaa 82920 tttttattta tcggtttttg tttggtataa agtttttagg aattttttaa tagttttagt 82980 tagaaacgtg tttttgtttg gttatgtgga aaattttata tatattaaga tatatgatgt 83040 ttttggtttt ttttacgaat gttttatgtt ttttgggttt atgatttgga atttgtagat 83100 ttttgttgtt tttgttttag agttataagg attttggatg taggaaatat tttttatgtg 83160 taagggtttt tttttttttt gttagggttt atcggttttt ttttgtttat aggtgttatt 83220 taaatttttg tatttgtggt tttttttttt taattatttc gtgtaattcg ttaatagttt 83280 ttttattttt agagtttggt tgttggagat atataaggta tatagaattc gtgaaatgat 83340 attgagtatt tattaggtat ttattgtgtg tttcgtttgg taataataag taaaattata 83400 atgttttggg tatatgagta tattttttta tgtttatttt tttagtaatt taatgagatg 83460 gttttataaa tggggaaatt gaggataggg aggttagatt ggtttaaagt tataggttag 83520 gaggggtagg gttaaaattt aaatttagat agtttggtat taaattttag ttttttatac 83580 gaaaggtatt ttgtaatttt tcgagaaggt tgggattatt atttttattg tatagatgag 83640 gaaattaaga tgttaaatgg ttagatagtt ttggagttag gaggtgggtt tagtggttta 83700 tgggagtata tggaatggag tttatgggag gttcgaggtt gggatttcgt attttatttt 83760 ggtttaaggg atgaggtgat tgggagtgtt agagatattt tgggattggt tatttaggtg 83820 ttttgtattt agttttagcg ttgagtgggc gagggtggat aatttgttat ttagtagggt 83880 tgttgttcgt atttcggtgg ttttttaaag tttggttaag taaagtaaga ttgttttcgg 83940 attagagtga tttttaagtt atataagtat ttagttatgt ttcggaggat gtaggattgg 84000 gaaggttttt tttttatcgt atttttattt agttttttta tggggtagtt ggttttaggt 84060 atagattaga cgtttttttt tttgtttgtt gtcggtatgt ttttggtttt attgttgttt 84120 tagggagggg tttaagagtt tttcggtttc gttatttatt atatttcgtt tagagggtcg 84180 ggggtttagt attaacgtta agtatttagt agtaaaatta cgggttggaa agagttatag 84240 tgttgttttg atttggtttt attttatatc gggtgtcgtt tttattagtt tttttttgtt 84300 tttggtttta ttttttaggt attataagtt ttgtaggttt aaagttaaat ttattagttt 84360 ttgatttttt ttagttggga ttagggtgag gttttcgttt aggtgtaaaa gttaaggtag 84420 tgttaaaaaa tttaggaatt aaataatatt ttgaagtaat attttaaata aattaaattt 84480 tacgttgaat aaattttgat agggttgtgt acgtgtaggg ttgggtttgt tttaatttaa 84540 aattttaata tttgtttatt atagagatta ttatgtatta tttcgatatt gaaaaatatt 84600 gtattaaata ttatttgtgt tgatttttga gttttttggt gtttttttat attttgtttt 84660 tgataagtgt ttgatatatt ttgttttagt cggttttgtt ttttaggtgt ttttttgggg 84720 ttgttttgtt tacgtttttc gtagttatta ggagttattg agttattgta tttgttttat 84780 tttgtttttt atgttttcgt atcgtttatt tcgttatgtt tttttcgtgt gttttggtcg 84840 tacgttagtt ttagatagga gttcggtggg ttgggagttt atattaatgt tgtttttttt 84900 cggtttcggt gtcgggtata gggtagtatt ggagattttt tttttttttt tttttttttt 84960 ttttttgaga tatagtttta ttttgttatt taggttggag tgtagtggcg taattttggt 85020 ttattgtaat ttttattttt taggtttaag ttttgttttt tggaattaag tagatttttt 85080 tgttttagtt tatcgagtag ttgggattat aggtatacgt tattatattt agttaatttt 85140 tatattttta gtagagacgg ggttttgtta tgttggttag gttggtttcg aatttttgat 85200 tttaggtgat ttgtttgttt taatttttta aagtgttggg attataggtg tgaggtatta 85260 cgtttggtcg agattttttg aataaataaa tattatcggt atggagattc gtttagggaa 85320 tttgtttaga ttttgttatt gtatttttgt ttgttgcgtt tagaggtaat ttagggtcgt 85380 tttagtcgtt tttatttggt tattttttgg tttttattta ggtcggtttg ttttattttg 85440 tgggttaaga aaacgattta gtgggtggtg attagtattt tttttttaat ttgaaaagaa 85500 tatatttatt agcggtggta gtaatttaat gttttttagt tgatgaaggt aatatgtttg 85560 tttataatgg aatggtttat gttatggtgg aatattattt agggacgtat tggtatttgt 85620 tataatgtgg atggattttg gaaatatgat attaagtgga gaagttagat ataaaggtta 85680 aacgtgtaat tttttgtata agaaatgttt agaatcggtt aggcgtagta gtttacgttt 85740 gtaattttag aattttggga ggttaaggta ggaggattat ttgagtttag gagtttaaga 85800 ttagtttggg taatatggtg aaattttatt tttataaaaa atataaaaat tagtcgggta 85860 tggtggtata ggtttgtagt tttagttatt cgggaggtta tggtgggagg atggtttgag 85920 tttgggaggt ggaggttgta gtgagtagag attgagttat tgtattttag tttgggtgat 85980 agagtgagat tttattttaa aaaaaaaaaa aaaaaaaaaa agaatttata tagataggaa 86040 ggaaatatgg aggaggaggg taggattgat agttaaaggt tacggggttt ttttttaaga 86100 aaaaaatttt ttaaattttt taaattttta attttttaaa attggttgtg gtgacgatgg 86160 ttgtattatt ttttgaatag attgaaaatt atggaattat gtattttaaa tgggtggatt 86220 gggttacgcg gtgatttatg tttgtaattt tagtattttg ggaggttgag gcgggtggat 86280 tatttgaggt taggagttcg agattagttt taatatggag aaatttcgtt tttattaaaa 86340 atataaaatt agtcgggcgt agtggtatat gtttgtaatt ttagttattc gggaggttga 86400 ggtaggagaa ttggttgaat ttaggaggcg gaggttgtag ttagtcgaga tggcgttatt 86460 gtattttagt ttaggcgata agagtgaaat ttcgttttaa aaaaataaat aaataaataa 86520 attggtggat tgtatagtag tttatttgga ttttaataaa gttgtttaaa aaaaaatgaa 86580 aaaaagtttt tttttttttt aaaataaata aataaaaaga aaaaaagaga gaggggaaaa 86640 aaaaaaaaaa aaagaaaata ttgagtgtag tatacgtatg gtaaaggtaa gaattttatt 86700 acggaaattt ggttttatta atatatttta tttttatttt tattttatat ataggtgtgt 86760 tttggttcgt ggtgttaatc gtatgttttt ttggaggttg tagtttagat tggttttgaa 86820 agttgttttt tgggtaattt taaatttttt ataatttttg aagtttttgg tttgttggga 86880 ttatttagtt ttttagattt agtttcgtta ttatttattt aagattgtag ttttggggag 86940 gggggttttt ttttaagggt gtaggggttt tgtggtttta ttttttttta gaatatatat 87000 tattttgtat tgtatatatg tgttttaata tggagtattt taggacgttg gttatagtta 87060 gttatgtttg tatatcgatt gatcgatcgt gttttgttga ttaattatgt taattatcgc 87120 gttgtatatt gtttttatta agcgagttaa agtaattttt tcggaataag ttgacggatt 87180 ttaaataagt taaaagatat ttttttagga aaaaaatagt aatgaatttt aagaagaaag 87240 aaaaattttt aaatttatag atttatggaa aaagtttaag tttttaaagt gttagatttt 87300 tttaaaagta ttaggtttag atggttttac gagtgaattt ttgaaaagtt ttaatagaga 87360 gattattatg ttgttgttta aaatgtttta gaaggtagag ggtaaaagaa atgtatttaa 87420 attgtttttg ttaagttagt ataatgtaga tattaaaatt gataaaaata gtatatatat 87480 atatatatat atatatatat atatacgttt tattcgtttt agattaagtt cgttgttgtg 87540 tatttaagta atattattta tttttatttc gttgttgaaa ttaaaatata ttttaatgga 87600 tttatgattt taatatgtaa aaatgaaatt atagaagtat tagaagaaaa cgtgggtgaa 87660 attttttttt ataattttag aacgtaggag atttttaaat aggatgtgaa ttttaaaagt 87720 taaaagggaa agtagagatt tgataatatt aggattaaaa tgttttgtgt agaagaatat 87780 tttagaaata aaattaaaag taggtagttg gggataagat attcgtattt gttgtgataa 87840 agatgtataa ataatttttt ttttttttta gataggattt tattttgtta tttaggttgg 87900 agtgtagtgg tatgattata gtttatagta gttttaaatt tttagattta aatgattttt 87960 ttatattagt ttttcgagta gtcgggatta taggcgtatt attttattta gttaattttt 88020 gtagagatgc ggttttgtta tgttgtttag gttggtttcg aatttttaag tttaagtaat 88080 tcgtttattt tagtttttta aagtgttggg attataggtg ttagttatta cgtttggttt 88140 ataaagaatt ttttttaaaa aattttaata agaaaaggat atatttttta aatgaaaaga 88200 gaatataggg ttttggttta taatatacga agagataatt tttttcgttt gatcgagatg 88260 tataaaataa aatattaatt ggagagtatt tggtttttag ttaggggtaa ggggtatagg 88320 atttttttgt tggattatta ttgtataggg tttagtagat agttgagtag gtcgacgagg 88380 ggaggggttt taaaaaattt tagtaattat tttagaggtt aatttaggaa taaggattaa 88440 tttttttttt tttttttttt ttttgatagg gagtttcgtt ttgttattta ggttggagtg 88500 taatggtacg attttggttt attgtaattt ttgtttgttg ggtttaagta agttttttgt 88560 tttagttttt tgagtaattg ggattatagg tataagttat tatgtttagt taatttttgt 88620 atttttagta gagatggggt tttattatgt tggttaggtt ggttttgaat ttttgatttt 88680 aagtgattag ttcgttttgg ttttttaaag tgttgggatt ataggtgtga gttattgtgt 88740 ttagtagatt aaaatttaaa tgtatatatt tttgatatag aaatttatta agagtttatt 88800 ttttagttat gtgtgtatat gtataagtgc gagaatattt gttgtagttt tttaattata 88860 gtgggaagtt ggataagttt ggtagggtta tgggatagtt gatgatataa ttattaaaag 88920 gaacgtgtta ttttgggagg tcgaggtggg cggattttaa ggttaggagt ttaagagtag 88980 tttggttaat atggtgaaat ttcgttttta ttaaaaatat aaaaattagt taggtgtggt 89040 ggtaagtatt tgtgatttta gttatttggg aggttgaggt aggagaatcg tttgaaagcg 89100 gaaggcgaaa ggtggaggtt atagtgagtt atagtgagtt gagatcgtat tattgtattt 89160 tagtttgggt tacgttttgt taaaaaaaaa aaaaaagaaa aagaaaaagg aacgtgttat 89220 atttataagt ggtaatagtg ttgttaaatg gaaaaaataa aagttggtag tagaagtttg 89280 attttttttg tgtttttgaa aagtttatat ttatatattg atttttttta tataagtttt 89340 gaatgatttt gtaggaataa aatttaggag aatgttatat ttagttgtta atatggttat 89400 tttttgggag agagttgggg aatgggagag aaaaattttt ttttaaattt tatgtgattt 89460 ttatttttta tttaagaatg attgggtatc gttttttttt ttttttttta gatgggagtt 89520 ttgttttgtt gtttaggttg gattgtattg gtataatttt agtttattgt aattttcgtt 89580 ttttgggttt aagtgatttt tttgttttag ttttttaagt agttgggatt ataggtgttc 89640 gttattacgt ttcgtcgtgt attgtttttt aggatgaaga aagggaaagg ttatagggag 89700 aatgggagtt agaatataga gtagggtttt taaatattag tttgcgggtg agagagatac 89760 ggggcgatat tatcggtttg gaatttaggg atggtatgag gtgttgttta ggggttttag 89820 ataaggtttg tttgttgatt aagtaagggt tgtgttggtt tttgtttatg tgtttgttta 89880 atacgaattt tttaggcgtt ttattttgtt ttacgaatta ttattgttta ttttaattac 89940 gttgtatagg aagaattgtg tttattttta taatgagaaa acggattaga gaggaaagtt 90000 attaggtagg gtaggggcgg tagtttaggt agtgtgaggg taaagtcggt gtttttttgt 90060 tattttttta tatacgagtg ggtaaggtat tataggagtt tatattttaa tttttgcggg 90120 ttattttgga aggcggtaga tggaattagt gatttttagg gttattttta gttttaggtt 90180 ttagataggg gtcgtggagt ggaatcgagt ttgatttagg tgtgttgatg gtagttatgt 90240 aattgtggat aaattatttt tttttttatt tgtattggat gagatcggga atttttattt 90300 tgggtttttt aagagttttg gggttttata gagtatattt agtagtagta gtgggatggg 90360 gggatagggt taggggagtt ttatgttttt tttaatttta attagagtat ttttatttta 90420 attttttttt gggtttagtg tttagagaga acgggaagga agtttagttt tggttatggg 90480 ttattttagt ttgttagtta tagtttatat tttaggagtt ttttttggat tgaaggagat 90540 agagttattt ataatattta tagaaaattt cggagaggaa gtggagttta attgaggaag 90600 cgtttttttg tagtttttag aaatgaggtt ataggtgaga tagtgtgtta gggtggatta 90660 tatggtattt ttttaggttg tttgttggaa tttagggttt ggttaggggt tgtttatatt 90720 ttgggtttcg aggcggggag tttgagtgcg tttttttagg gttgaatgtg ttttttgttt 90780 atatcgtata gagtatggtt gtttggtcgc ggcgcgtttt ttcggatagg ttcgttattg 90840 tgtagatttt taatttcggt agttgtttcg ggtttgggag gcggcgggta tagatatagt 90900 tttttttttt tttggtagtt gttttgattt tttgggataa gtgttgagag gcggttttat 90960 ttagtgttat gtgtttgggg gtcggggttt tattttgggg ttaggttggg tggttagggt 91020 tatagagttg tagggggcgg agtagagaaa tcgtttttag cgtttgtttt ttggttttat 91080 tttttttcgt agttgcgttt tatttaaggt attttatagt tgttcggtat tcgttgtatt 91140 ttcggattag tttttttttt tttttattat tgtacggtgt ttggtaggtc ggcgagggga 91200 ggggtttttt ttttgggttt tggagttagg ttttgttttt tggttttatt tcgttttatt 91260 acgaaggaga tatatcgggt ttggttaatt ttttcgtatt gatttttgtt tttttagtat 91320 atgcgggatt ttttatttta gatttaggtt tgagaggttt tagggatagt tcggagaagg 91380 agggtatttg tttttagaag gggaaagaga aagagattta attttaaagt aaaaggggat 91440 ttgggtgttt tttgtaagta gtttaggaaa atgggaggag gtgggagtag cgggattttt 91500 cgagtaaggt atttcggtag gaacgttagt gttttttgga tatttttaga agtagaagta 91560 tatagtttta tagaaaaatt ttgtaggttt aggattcgag gtatgatacg atttaaattt 91620 attgttttat tagatattag tgagtttttc gacgtttatt aaggtttttt gttttatatt 91680 tggtattgga cgaatttgta tattttgttt tagggagttt atagtttagg gataggttta 91740 gagtttatgt ggggtgtttt gtaaatacgg ggttagaagt tgggttgttt atggggtttt 91800 ttttttttaa attatagtgg ttattttttt tttaatttta tagtttttga tttttattag 91860 gaatttttgg ggtttagtag gtgttttttt tttgtaggtt gatgttcgtt ttttttattt 91920 tttatttagg tttagttttg attttatttt ttttaaagtt atttttttat tgttttgtgt 91980 tgggtggttt tagggagttt tgtgttttga ttaattttat atttaacgtt gtattggtag 92040 ttttgttgtt tgtgttgaga tttttttttg ttttgttttt ggaatatacg gttcggtgcg 92100 gattaagtat gcgaagagtt acgtttatta ttattagttc gggggggttt gattttttgt 92160 ttttttaacg ttttatttat atgataaaga tttttagatt ttttgggtta taggaaaatt 92220 attgagatat gttgttatgt ttatttcgtt ttaattttat atttatgttt ataagtggtt 92280 ttagaattat tgtggatttt ttttttggtt tttggggtgg gtggatatat gagagtttag 92340 tttttagtta tttttgtaga tgtttttttg atagattaag aaattgaggt tgggaggggt 92400 ggaatgatag tttagaatta gttgatttat ggggtagagt tgggatatgt ttagaattga 92460 gttgggtatt gggtttggtt ttttttttgt ttttagtgag tattttaaga aggtagagaa 92520 ttagatttat gaacgagcgt tgagtattcg ttttataagg tagttttgga gaaatttggt 92580 tggtgtggtt gaggagtcgg aggggggtaa ttttggtggg gggggttttg agttagtagt 92640 tagtttttgt aggtttagta ttgggtgttg tagtttagtt ttattttatt ttatttagag 92700 gtatttatgt tggggggtag gaaaagagta gggatttagg agaggaggta aggtcgtttt 92760 tatttagagt ttgagaggat tagggatgat tttaaaggat gagcgttttt ttgtgggagg 92820 atagtaagga gggtgttaag tttaggggta gggttagagt ttcggaaatc gagaatttat 92880 tttattagta taaagtttag attttattag gttttggggc ggaggagtag gtagggatgt 92940 ttttgttttt tgtagcgttt tttttttttt tttttttttt taattattta ggtgtttata 93000 tttttttttg aaatgttgat tttttttaga atttttatat tgaagttaat atttatttat 93060 tgagtttttt agtataattt ttagaggaga gattaggtgt tttgggggta aagttgatta 93120 ggaaagtttt tgtttggttt ttagggacga tttatggggg ttattatatt tgtttataag 93180 aattataaaa aagttatttt aatttattat tagtggttta tttttttagt ataattttat 93240 ggtatattta ttatgtttaa gttatttatt tggtatttta tgggattttt tttttttttt 93300 tttttttttt tgagataggg ttttattttg ttttttaggt tggagtgtag tggtataatt 93360 ttagtttatc gtagttttaa ttttttatgt ttaggtggtt tttttatttt aattttttta 93420 gtagttggga ttataagcgt atgttattat gtttggttaa ttttttgtat tttttgtaaa 93480 gatagggttt ttttatgttg tttaggttag ttttaaattt ttgggtttaa gtaatttgtt 93540 tgtttcggtt tttaaagtgt tggatttata ggtatgagtt attgtatttg gttttttatg 93600 ggatttttta taaaaattaa gataggttgg gtacggtggt atgattttag tattttggga 93660 ggttagggaa gttgaggtgg gtgggttacg aggttaggag ttcgagatta gtttggttta 93720 tatggtgaaa tttcgttttt attaaaaata taaaagttag ttaggcgtgg tagtttacgt 93780 ttatagtttt agttattcgg gaggttgagg tagaagaatc gtttgaattt gggaggtaga 93840 ggttgtagta agttgagatt atgttattgt attttagttt gggtgataga gagagatttt 93900 attttaaaaa ataaaaaata aaaaaaaaat ataaaaaaaa ataaagataa tagttttatt 93960 tttagaattt agtgggggta tgaaaggaat tttgaagatt atatagtaaa attttaagta 94020 tggatatcgt tggtttatag gtgaatttta ggtttttttt tatttttgta ttttttgtat 94080 tttaaagaaa gggtattcga ttatttttta tgatttgaaa aattattttt atatttaaaa 94140 aaaaaagttt agtagaggaa agaaagttta tatataaatt atttatattt taagttaaat 94200 acgaggtatt tggattaggt tttgagggat gtataggagt ttattaaggt agtgatgtaa 94260 agagaagtag aggttagggt ttaggaggtt agggtaaagg ggttgtgagg aaaggtgtga 94320 gagattaagg gaagattaaa gtaggagaag ttgggaagga gagaggtgtg agttgagtag 94380 gagagtgaat taatcgtgga ggggtttatg gtgagtgagt agagaaggtt tagtacggga 94440 agagatttta gtagtgttgt gttttgggga agttagtttg ggagtaattt agttggggtt 94500 ttaggagatt ttgttttgta tttatagttt tggggtggag ataaattata gtatagatgt 94560 tttttcgtag gtagaagtta aggggttggg cgtttgttta gagggtacgg aatttttttt 94620 atgatttttt tttttatggt gttagttgga tttttggtgt tcgggggata gaggggtcgt 94680 agagattggt tagagttgtg tatgtcgggg tttagggaat ttttagttta gttttatatg 94740 gaggggtaga aggggatggg tttgaaggaa agatgggtag gaagttgagt tggagagaat 94800 tggattcgtg tttagaacgg tcgtgatata gagagggagg acggagaagt aagtaggtgg 94860 tgtttcggag gaagaattag tggggtttag gtttgggttt ttcgagaagt tatttttatc 94920 ggattttaag agtatttttt tattgggaag gttttgtttt cgtttgtttt tgtatttttt 94980 ttatttggat ttgtttaggt ttttaggatt gttagtttag tttacggatt tttttacgtg 95040 agttggattt ttatttgtat aggtttttgt tcgtgggtgg tcgggtttgg gatgttgatg 95100 gttttttttt atgtttcggt tttaacgtgt atattttatt ttatggagaa agttatcgtt 95160 tttttagagc gttaggtttt tggtagtttt gaacgttgtt gtttttacgt ggtttgtttt 95220 tttttttttt ttttggtttg atgaaattgt atttttattg ttggggaagt tttttggata 95280 ttttttgtgt tttagttatt ttgtttacgg ttcggtgagt tttagaaagt agagttcgta 95340 ggttgtgttt ttgggtttgg ttttcggtat agtttttggt ataatttagg ggttaaattg 95400 tgtttgtttt tggaggagaa tgtttttgta tatttttatg gatatttttt tatttgtttt 95460 ttagagttag gattacgttt ttgtgtattt agtattagtt attatcgaga tttagatggt 95520 tcggtgataa tcgttttttt agttatattt tgtttgattt agttgagtgt gaatatatta 95580 atttaggatg ggggtgtatt cggtacgtta aataaaggtt ttgtattaat agaaggtagg 95640 ggaggaaata gttttttgtt attttgtaaa ttgtttatgt ttttggtttg atattatgtt 95700 attagtaatt attgttattg agtttgggtg gttggggtag ggtggttttt tagagttaag 95760 tttagagaga tgggagaggg aatacgggat tcgtatattg agggtcggaa aggatttttt 95820 aaggtttatt agtttttggt tatttagtgt gtttcgatgt tttttttgta ggaaatgtag 95880 agttttaggt tttagattcg ttaagataaa tgtgtatttt atatgtttat gaaagtatga 95940 ggagtattgg ttttttttta aatttatatt ttttttaggt tttatatttt tttagttttt 96000 aagtttattg attattggag aatttttatt taaaaagaaa aattaaaaag gggttgggtg 96060 gtttatgttt ataattttaa tattttggga ggtcgaggta ggaggtttat ttgaatttag 96120 gagtttgaga ttagtttggg taatttagtg agaatttgtt tttataaaaa aaatttaaaa 96180 attagttagg tatggtggcg cgtaatttgt ggttttaggt atttgggagg ttgaggttgg 96240 ggaattattt gagtttaggg ggtagaggtt gtagtaagta gtgattatat tattgtacgt 96300 tagtttggag gatagagtaa gattttgttt taaaaaagtt aaagaaaagt taaagaagat 96360 ggaaagaggg atttagagag atgtggaagt aatttaaggg tttatcgatg gaggaatagt 96420 tatataatat aagtgtatcg tataatagaa tattatttag tttttgaaag gaaggaaatt 96480 ttgttttatg ttatagtacg acggatgaat ttttaggacg ttatgttgag tgaaatgagt 96540 tagatataaa atgggtagtt attgtatttt tttatatata taaggttttt agagtggtta 96600 aataaattta taataaagat agaaaataga atggtggttg ttagtagttg ggggaggggt 96660 atggggagtt tggtttaacg gggacggagt ttagtttggg aggatgaaaa gggtatcgga 96720 gatggatagc ggtggtagtt gcgtaatatc gtgaatgtat tgaatgtcgt tgaaacgtat 96780 attgtaaagt ggttaaaatt gtatattgta tgttgtgtat tttattacgg ttagaaataa 96840 gaagtagtag ttaaattaaa aatttagatt gtgttgtttg tttaatttaa agaaggttta 96900 ttgagtatta ttgagttttg attttgtgtt tagaattaga tttggttttt gaggggtttt 96960 taatttagtt ggtattttat tatagtttta tggagttacg atttttgttg gggttagggg 97020 gtacgttttt gagaagggat ttaattatgt tttatagttt ggtattttta aataggtttt 97080 gtgttttata ggattggtat taattttttg tttgtaagtt ttatgttagt acggttgtgg 97140 gtttgagttt ttttaggacg ttgttggagt tttatggttt tttttttttc gttagaaggg 97200 tatttttaaa taaaatcgtg tgtagttatt atatagtttt ttggtttagg tatttttttt 97260 tagtgttttg agaattttgt tttgtaggtt aaggtgtttt ttatgttttt ttttttttgt 97320 tataattatt ttttttgggg gaggaggatt agattatggg ttttaatgta agttttagga 97380 ggtatacgtt tttttttttt tttttaagtt ttcggttttt gttgggtata tttaggtagt 97440 ttgtaatttt ttaagtagga gttattagaa tgtgatagtt tttttagggg ttttaatttt 97500 attttgtttt atatttttgt atgagtttgt tttggttttt gcgtggtttt ttatttttta 97560 agttttttag gttttttagg gatatatagt agatagaggt tttagtaagg tttacggtga 97620 tttataaagg aggttttttg aaatttagaa aattttttta aatttttatt taagtttcgt 97680 ttggggtatt ttggtatgtt tttattagat agagagagtt attttttttg agtttgtaga 97740 tttttatttt tatgtatttc ggtttttttg ggtttttagg gtagtatttt ttattttata 97800 tttagttttt ttttttaaga ttttgtggta aagttagtaa ttaggttttt tattattata 97860 gtatttaaga tttagcgttt tgcgatttat ttttttggtt tcggggtgta gttttagtta 97920 tagggggttg gggtttgggt tttagtttgt tttgtagttg agatataggg gtaggttttg 97980 aattttttaa ggtttgggtt gggttggggg cggtgggcgt tttagtaggt ttgggtattt 98040 ggatttttat ttttttgggg gttgcgtcgg tggtaggggt agtgggtatt tcggggattt 98100 tggaggtagg gggttttatt tttcggtggg ttgatttttg gggtttgacg atggtgattt 98160 tcgtttttcg aggggtcggt tttggcgttt tgtggtttaa tatttcggtt tttttgagtt 98220 cgaatcggga cgggtcgatg gtttcggcgt tttttatttg tttggacgag atgttaatgg 98280 atagtttagt gcgtcgggat atcggttcgg tcgttttggg gttcgagagt tttatttttc 98340 gtagggacgt tttgggggag cgttggttta gggagtttat atggcgggtc gagggttttg 98400 agttttttac gtttaggttt tggaattttt gggtggagtt ggttatagtg gttcggagta 98460 ggggagtttg gatttttcgg ggtggggtgg agttgggtgt ttcgattttt tcgattttaa 98520 aagatttttt taaggttgaa aaataaagag aggggatgta attggtgaat ggatggttag 98580 ggaatatttc ggtatgtttt ttgttaagga gtagtagagg aaggtaggcg atgcggcggt 98640 gagggtcggg ggtttttttt cgttttttat gttttagtaa gcggaaggga tagttttatt 98700 ttaggagaat tattatgagt tttggggtag agatgtaggt tggagtggga agatgttgtt 98760 cgtcgtgttt tgttatggtt acggcgtaaa ttatatagtt ttttttttta gttacgttta 98820 tataggaacg ttttagtttt agagaagatt tttatttttt tttttttttt tttgagatgg 98880 agttttgttt tgttgttttg gttggagtgt agcggtattt ttcgggttta agcgattttt 98940 ttattttagt ttttttagta gttgggatta taggtacggg ttattatgtt tggttaattt 99000 ttgtattttt agtagagatg gggttttatt atgttggtta gtttggtttc ggatttttga 99060 ttttaagcga tttattcgtt tcggtttttt aaagtgttgg gattataggc gtgcgttatc 99120 gtgttcggtt ttgatttttt ttttgtcgcg gttgttttta ttttttttta tttttagtta 99180 aggtatatat tgggatatta ttagtaaata tatttttatt attagttata gcgggggata 99240 tgtttttaat aataagtgat cgtaattgta attaattaga atcgtagtag gaataaaatt 99300 ttattaatga tattaagggc ggatattgga gtttttagtg tcggcgaggc gtcgggttta 99360 tcgagtttat tatatttgta gtcgtttaat tttgggatgt aaagaatatt agtattttta 99420 gtatagatgg ggaaagtggg gtacggggta gatatagagt tagattgtat attaggttga 99480 tattagagtt taaggtttta attatttggt tgttcggttt ttttagttta gtttatagga 99540 attaattttt ttagttatta gttttttttg tattttttta tttattatta taagttcgtg 99600 tagtgatgtt aattattagt tttcgttttg tagttatttt gtttttttat tagggtttgt 99660 tttttcggag gtagtgggga tggtatttgg gaagttgtta tttttatagt ttttataatc 99720 gtattttaaa tgagagttag tcgtttttgg ttattagggt tagagtaggg agggatttat 99780 atggtaggta tatttattag tttttttttt aggttagatt tatagcgtat ttttgtggag 99840 atttatagtg tttttttagt cgttttttgt tttattaggt tatagagttc gggttttatg 99900 ggattttatt attgtttttt ttgtttatag gaaaagggat gatagttggt ttttagtttt 99960 taataatagc gttttaggat taattttagt gttttttttt tattcgtttt ttttttttta 100020 aatgtattta ggtattgggg aggggaagag gaagtttaat tttttaattt tggtcgtttt 100080 agttgttagt tttttgggta aggtattttt gtgggcgttt tttttaagtt ataggtattt 100140 tttttttttg gtggatatag acgaaatttt gggttattaa gtttaatttt tattagaagt 100200 tgggtaagga gtcgtgtgga ttttagagaa tttttagttg ttataggttt tgttttagtt 100260 tcgttattgt tttagaggat atgggttcgg cgtggttaga gttgtttatt ttttaagaga 100320 gtagaaattt ggatttttat atgatatttt ttgattttta aatgttggta taaagtaaaa 100380 taagtttttt ttaaaatatt gagtagtttg gttgatgtgg tgaaatttta tttttattaa 100440 aaataaaaaa ttagttgggt atggtgatat tcgtttatag ttttagttat ttaggaggtt 100500 gaggtaggag aatcgtttga attcgggagg tagaggttgt agagttgaga tcgtgttatt 100560 gtatttagtt tgattgatag agcgagattt tgtttttata aattaaaatt aaaaataaaa 100620 taaaatatcg tagggttaaa taaaattaaa tttataggtt gtattcgttt atgggtttag 100680 ttatgatttt tagttgatta cgtggtcgta gggtagtagg atattgagtt ttagagttag 100740 gggtgtgtta ggtgtgggtt ttcgatatgg tgtttttttg tttttttgta ttttgtatgt 100800 aaattgttgg ttgtgttttg attttgtaga agttttaggg ttttaaggaa aggttgaatg 100860 tttattttta ttagttagaa agtttagggt ttaatgttta gaattgaatg taatgagatg 100920 ggtttattaa gtttattata tttatattcg tttaaatttg ggttgtaaag aatattatta 100980 tcgttttcgt atagatgggg aaagtgaagt acggggtaga tatagagtta gattgtatat 101040 cgggttgatg ttagaaagtg tagagtttaa tgtttgggtt ttcgtgcggt ttttagggtt 101100 tttcgcggtt ttttgatttg ttttttgttt tttgagtatt gtttaaattg tttttatatg 101160 gtgtgttttt gttttatggg tgttgtagag taggggtcgg tttttaggtg tttttagtat 101220 tttttcgtgc ggttaagttg gagaatagaa attagatagg agaaggtttt gttttaggtt 101280 taatttaaga aaataaatga ttttttttgg gagattcggt gaattttttt tttgggagtt 101340 tttttggagt tatttttatt atggttaatt tatgatcgaa gatattgtat taaagtagag 101400 gttgttttgg tgtgagttta cgattgagtt tacggtgcgg atgtaatgat ttattttagt 101460 taggtttacg tgtataagcg gattatttta gaatcggagt tggttttttt tttagggtat 101520 tttttttttt tttagttgtt tgcgtggttg gcgttttatt attttggtta tttgcgtaaa 101580 atgtatatgt gtgtcggttt ttaattattt tttttttttt tttaatgttt ggtgtttttt 101640 tatggatggg tttttttttt tttattagtt ggtttttgtg tttattgttt ggttttatga 101700 tttttttggg tgtttcggtt tagtattatt tttatgttta ttagttttta gtaagttttg 101760 agatagtagg ggttgtttta ttcgtagggg ttattttatt attaggacgg cgttgtttaa 101820 aggcgagttt gttttagata atagttagga gattttatag tttttagaat tgtaagagaa 101880 tataattgtg tgttagaaga atagtgagaa taggaggcgt tttatttcgg aggtgtttat 101940 tttttttagg agatgtttta ttttgggggt gtttattttt tttaaggaaa ttatgtttcg 102000 gttggaatgt taagaaggtg atatttaaat gaagaggtgt ttattttggt ttacgttatt 102060 tttttaaacg agtatgttat cgtttttttt tttttttggg aatttttttt aaagttaagt 102120 ttattttagt ttttttttcg gggagttggt tttttatata gtttatatta tttttttttt 102180 atgttatttt ggttacgtta tgattgttga gattggttac gaggggtgtg tttcggtttt 102240 tcgggaatag agttgaatgt tttttatttt atgatattat gtttttatta ggttttaggc 102300 gtttttagaa aatttattaa gttaggcgtg gtggtttacg tttgtaattt taatattttg 102360 ggaagttaag gtggatagat cgtttgagtt taggagttta agataaattt gggtaatatg 102420 gtaaagtttc gattttatta aataatataa aaattggtta ggggtggtgg tatatgtttg 102480 taattttagt tattcgagag gttgaggtga gaggattatt tgaggttagg agattaaggt 102540 tgtagtgagt tatgattata ttattatatt ttagtttgga tgatagagtg agattttgtt 102600 ttaaaaaaaa aaaataatta aaatttatta aatgttaggc gtggtggttt atgtttgtaa 102660 ttttagtatt ttgggaggtt aaggtaggtt taaggtaggc ggattatttg aggttaggag 102720 ttcgaaatta gtttggttaa tatggtaaaa ttttgttttt attaaaaata taaaaaatta 102780 gttaggtatg ggggtgggcg tttgtaattt tagttatttg gaaggttgag gtagaagaat 102840 tatttaaatt cgggaggtag aggttgtagt gagtttagat cgtgttatag tattttagtt 102900 tgggcgataa agtaagattt tattttaaaa aaaaggttgg attataggat tataggatag 102960 gtataagttt tgagggagtt tttaaggagg agggacgtat tagattttta tttttatttt 103020 agtttgtgaa gatttatttt cgtttgaggt tttgtagagg gttgattagt gatttttaaa 103080 aagatatgtt taatatttaa ttttaagaat ttacgaatgt gattttattt ggaaaaaggg 103140 tttttgtaga tgtgattagg gatttcggga tgagattatt ttggatttgg gatgggtttt 103200 aaatttagtg ttcggtgttt ttataggaga aaggtagaag gggatttggg atataaagag 103260 atacggtggg gagggttacg tgatgagagt agagattgta gatgttgtta gagttaagga 103320 gcgtttgggt taacgtaagt tggaggaggt aaggaagggt ttttttttcg agttgtcgga 103380 gggagtgtgg ttttgttaat attttgatgt taaatttgtg gtttttagaa ttatgagcga 103440 attaattttt gttgggttat ttggttttta gtaatttgtt ttagtagttt taggatattt 103500 ataacgagat ttttgggaag atgaaatttt tggttgtata gtggtttagg gtgaggttag 103560 ttggtgtggt tatttatttt ttagtttagt tttaatttta ttataattat attcgataaa 103620 tggtttattg tgggttaacg gatacgtggt tattttagag ttgttatatt aggagtttag 103680 aggagcgaga gttgtttttt tttttttttt tggagtcgta taaaaatttt agatggttgg 103740 agaagttatc ggaggaatta tattatttta gatttttgtt ttattgttgg gatatgtggt 103800 aatgaaataa gattattttt gttagggatg ttttatgggt aattgttttt ttacggagga 103860 tattgtgagt tgtatttagt cgggaaatat taggagatgt ttgttattag gttggtagaa 103920 tagggttttt tagtattttt ttttttatta gagttttaag attgcgtttt gggttttgta 103980 gttatatacg gtcgtttttt tttttttaat gtgtaggttt tttgggaagt tttttgttat 104040 tatttttata gtggaatcgg tataatttgt ttaggggtag taggtttttg ttattttata 104100 cgtttttatt ttttttgtgg agggagacgt agttaagggg tatttatatt tatttataga 104160 agcgagagtg ttcgtgagtt tgttattttg tagattttag aatttcgtac gtgattgtat 104220 agatttatag gtttaattgg gtagatttaa aggatttacg tagtagggag gagtatcgga 104280 tagttttttt ttttgtttgt aaggagttaa tgtaattgaa ggatatagaa gaggttttta 104340 gttgagtatt ataattgtgg atcgtgtata gtgttagaaa gatgcggagt taggttatgt 104400 tgggaggatt tttatgttgt tattggaagg taaagtagtg ttattttttt atttatagag 104460 taggaggttt ttatttttgt tagttatttt ttttatttgt gaatttaagt tttttaaagt 104520 tagattttaa tttcgtaagt ttttaaaagt ttttttgggt ttttttttta atttttatcg 104580 attttaattt gttttaaaag tttgaagatc gtttatgtgt tttggtttat ttttgggaat 104640 ttattttaag gaaataatta gaagtataga aagatttacg tacgaggata tttgtattag 104700 tattaaattg ataaaatttg gaaatagttc gggttttcgt agatttttta aatttatatg 104760 ttaaaggttt gtattattat taaaattata tttttgaaga tgagaaatgt cgagaatatt 104820 aagtaaaaat agtaggatat aagatgtata taaagatttt aattttattt tatatatata 104880 tgtgtagttt gtacgtatat atatatttat attcgggtag aaaataacga tttttggatg 104940 gaatgaatgg cggtgggtgt tgtttattat atttttttgt tttttgagat gtttatatta 105000 tatggggatt atttagtatg tttagggaat aaaattatcg atattgtttt tttttttttt 105060 tttttttgag atagtttcgt tttgtcgttt agattggagt gtagtggcgt aatttcggtt 105120 tatcgtaagt tttatttttt aggtttacgt tatttttttg ttttagtttt tcgagtagtt 105180 gggattatag gtgttcggtt attacgtttg gttaattttt ttgtattttt agtagagata 105240 cgattttatc gtgttagtta ggatggtttt aatttgttga ttttatgatt cgtttgtttc 105300 ggttttttaa agtgttgcga ttataggcgt gagttattgt attcggttaa tattgttttt 105360 aaaaaatata ttttggtatt ggttgggtat ggtggtttat atttataatt ttagtatttt 105420 gggaatttga ggttagagga tcgtttgagt taggagttcg agattagttt gggtaaatgg 105480 taagatttta tgttggaaaa ataaaattaa aaaaaaaaaa atatatatat atatagattt 105540 tgatgttaat aagttggagg gtgtgggtaa ttgtatgttg gtttattttt atttttattt 105600 ttggaaaaat attttatagt ttaggatggg tatagggttt tttttatttt taagtattta 105660 cggttttagt tgttatataa aaagaggtta tagtgggtta ttttttagat gtaaattttt 105720 ttttttaggt ttatggcggg gtcgaaatag gagtagtttg gatttgggtt tatttagaga 105780 ggaatgtgtc gtataaggga ttattgttaa ggtttttgtt ttgattatag gttgtttggt 105840 aaatcgtttt tagtttttga aattagatta agtatttttt ggtgtatata ttaggtttta 105900 gtttggggag ggaatattaa gcgagttata gagttttgtt ttagtttggg ataaatgtta 105960 tgtaaagaaa tggtagagtt taaggttaga ataattttat gcgtagttta gttttcgtag 106020 gagggagtaa cgtggttttt gtttagggta gggtggaatt ttaggtttag gttttaggaa 106080 cgttagtttt ggttaaattg ggtttttttt gagtagtagt aaagtaggtt ttgtttttga 106140 agaaatattg gttatttagg agttagggtt agggtttagg gaagtcggat agatggtgtt 106200 aaggagtagg gaagtatttt tttgtatgtt attttgagtt tgtaggaaaa agttacggga 106260 aaattttatt tggtagataa ttttttataa tttttaggat ttatagagtg agtttagtag 106320 tatgtacgtt atgggtattt ttttgttttt atttttttgt gatattggat tttggtatag 106380 gtttttgatt tgtgtagggt ggggtgggta gttaggtagg gttttggcgt tggtagagtg 106440 gggtttagtt gtaaaggttt ttttattttt tatttattta ggatttgggg gacgaggttt 106500 aaaggtttgg tgtgttttta aggagtttaa ggattgtttt agggttggag ataggacgta 106560 tgggtttgta tagggatcgt gttttttatt ttagggttga gagtaggaga attaaatagg 106620 agagtgatat aattatagtt tattttgagt tttagtgttt ttagtgttat ttgttgtagg 106680 aggtgatggg gtaataaggt gtttttgagg ttaggcgcgg tggtttatgt ttgtaatttt 106740 aatattttgg gaggttgagg tgggtggatt atttgaggtt aggagttcga gattagtttg 106800 attaaaatgg agaaatttta tttttattaa aaatataaaa atagttaggc gtggtggtgt 106860 atgtttgtaa ttttagttat tcgggaggtt gaggtagaat agtttgaatt taggaggcgg 106920 aggttgtggt gagtcgagat tgtgttattg tattttattt tgggtaataa gagcgtaatt 106980 ttattttaaa taaaaataaa taaataaata aaaaataaga ttttttgggt gtaggtatgg 107040 tacgcggtag gggtgattgt tgttggtgta attattattt tttgggtgtg tgtttgtggg 107100 ggttgtgtat gttgaaatgt gtggttattt tgttggtgat taaggttgtt ttggttttat 107160 tgttattaat tacgtttatt gattttatat ggtttatttt cgtgttttta tttagagttt 107220 tttttagtgt ttaagttttc ggaaggttgg aaggagtgag tagtgtagtt tttggttaag 107280 aattgaagta taaaaatttt agttttttta tttaatttta ggtgggataa ggttgggggt 107340 acggtttgta gtttttttat gttgttcggt atgggggttg ggtagttatt tgtggttata 107400 atgagttggt gaggtatttt ttattggttg gattttttgt ttggtttatt tttatattta 107460 ggtatttttt ggtgtttttt tttattgaaa tttttgtttt aggatttgtt tttggaggga 107520 tataaattag ttttttagaa ttggtttggg ttgtttggtg gaggagggag gtggtttttg 107580 gggtaggtgg agtaggtttc ggatagggag gaggatatag ttggggtgat ggggaggggt 107640 gtgtttttag gaagtaaaat cgtttaaaag gaaaggttta aaaataggcg tagtgaagtt 107700 gagcggagtt tgtaaaggga agttaggaaa tagtagtgtt agtggagggc ggtttttagg 107760 ttttttatag agagttatat ttgtttaggg atagggataa cgtgaataga aggtaaagtt 107820 tatattaagg cggaggaggc gttttttttt tagagagtcg tagttagata gtttaaattt 107880 gttaaaggtt tgggagggaa gaattagggt attattttat ttttagttta attttttttt 107940 tagttttttt tttttttgtt tttttaaggt taggtttggt tgggttatag tgttagtagt 108000 taagattcgt ttttagtgtc ggtttagttc gtaggaggtt agtttggtgg ttaaaggtta 108060 ttgattgttt aggtttattt gtatacgtgg tttaatgatt gaggtttggg atttggggtt 108120 attatttata gtatttttgg ataaggagga aaagaattat ttttattaat ttttggatgg 108180 aggtgtaggg agcgttaata gtatttttga aaattttaaa tgtattaggg gggttagtat 108240 ttagggaaga gttataggag gttattttga tggattttga tgattatttt tgtttaagtg 108300 ttaggaggag gttttttttt ttttgttttt ggtaattttg ggtttaagaa gttttaggta 108360 tttcggaggt tttttttgtt tattatagtt ttatttaaga ggtttggttt attttgtaat 108420 gatgatgtga gaatgagtag gtttgtttag tgttagagtt tgtggttgga ttttcggttg 108480 aggttaagag aaataaataa gttttttttt tttttttgta cgttatagga agagtagttc 108540 gttggttgta aggggatttt ttattttgtt tatggggtat agtagtttat agtatttttt 108600 ttagaaacgg agtattggta ggtttgggtt tttgtaagat ggaatataaa ggggtgggta 108660 gttgatttta atagttagtt tttgggattt taaatttttt tttatttttt aattttgtga 108720 tgttaatttt tttttggata aagtttttta ataatttggt aagttagtat tagttgaatt 108780 agttttagtt tgaattagta gtttttttta gtttagttat agttttattt ttttagaagg 108840 gaaaagaagt tttacggatt tttttataag gaatttttag aatttgttat ggtgttcgta 108900 ggggatattg gtattaattt tgggtttatt aaatgtagtg ggtttaatag tgttttttaa 108960 aacgatatgt tttaagtttt aatttttgga atttgcgaat atgattatat ttggaaaacg 109020 gatttttgta gatgtaatta aggtaagggt tttaaggtga gattattttg aatttagtgg 109080 gttttaaatt taatggtgag tatttttata aaagatagaa aaggagaaag atatatagat 109140 agggggagaa agttacgtgg agataggggt tagagattag agatgatggt gatgcgtttg 109200 taggttaagg aacgttagga atttttagga gtcgtcggaa gttatgtttg taagttttta 109260 ggttgtggta ttttgttata gtaattttag gatatagatt ttaggaatag aatatagaaa 109320 agaaacggga ggaggtttag agtttgttgt ggttatttta gttattttat tcgatttttt 109380 tagtgtttcg ttaattttga agtttttttt agttattgag ttatcggttt tgaaaaggag 109440 atatgggtgt tttggagttg gtttagtttg gtaggaggta gtttcgtttt attgtttttt 109500 tattagttat tagtttatat aggtttttta tagtgggtaa gtgcgttgtt gttttagttt 109560 tcgtcggttt tttttttgtt cggttttatt agtcgtagag ttttttgttg ttgttttttt 109620 tggtttaaga ggtttatata tttagttttt ttgggataaa tttagtttat atttgttgtt 109680 ttatcgtagt tatttaaggg ttttttttat taacgtgttt tttaagggat agtaagttat 109740 acggtcgttt tatttggggt tagaattgtg ttttattaga gtaaggtttt ggagtaatta 109800 tatttagggt tagggagtta tttgtttaag aatagaaacg tgtggtcggg cgcggcggtt 109860 tacgtttgta attttagtat tttgggaggt agaggcgggt agattacgag gttaggagat 109920 cgagattatt ttggttaata tagtgaaatt tcgtttttat taaaaatata aaaaattagt 109980 cgggcgtggt ggcgggcgtt tgtagtttta gttattcggg aggttgaggt aggagaatgg 110040 cgtgaattcg ggaggcggag tttgtagcga gtcgagatcg cgttattgta ttttagtttg 110100 ggcgatagag cgagatttcg ttttaaaaaa aaaaaaaaaa agcgaaatgt gtagtttttt 110160 ttttttttat ttttgaaata tgaaggggag gtgattgtag gttttttggg aaagattttt 110220 ttattttttt tttttttttt tttttttaag acggagtttt gttttgtcgt ttaggttgcg 110280 gtgtagtggt gttatttttg tttattgtaa gtttcgtttt tcgggtttat gttatttttt 110340 tgttttcgtt tttcgagtag ttgggattac gggcgtttgt ttgggatagt tacgtagtag 110400 tttttgtttt aagttatttt tttttacgta gagtagaatt aggattatag taaaggtttt 110460 agaggaggtt atcgtttata gggttttggg tttttttttt gaaaggtagt ttagttttta 110520 agagggtaat agcgattgat tcgggacgaa ggtttttttg tgtttgtttt cgttatttat 110580 cgcgtgtttt tggtttcggt agttataggg ttattttagg cggattttaa agtggcgtta 110640 agttgttgga tttttttttt tttttattaa attagttatg ggaatgggag tatttttggt 110700 atatttttag atgtgttgta ttggtttagc gtttttttta ttttcgggtt ttaaattagt 110760 tgttggttgt tttattagga gtagattgag gggaaatggg cggaagtcgt aggggaagag 110820 atgtgaggta gataaagagg aagaattttt tggttggggt ggggtcgtta gggtttgggt 110880 gggagggtcg tttatttttc gtttttggtg gaaggtagta gaagggtggg acggatttgt 110940 gtgggagggt ttaggtgtgg tttgtttggg ggtaggagag ggattagatg attttttagg 111000 tttttttggg ttaaagattt tttgataaat ggttgtcgtt gaaggtagga gcgaggtttt 111060 gggaggtgat tgatttcgaa aaattatagg ttgtagtttt gagggtttta aaggttaagt 111120 acggagtttt ttaaaatgag gtttttttta gttttaattt atttacgttt tttaggtggt 111180 tttagatatt tcgttagggt ttttttggta gtttttcgtt ttcgattttg gagatagaga 111240 aacgtgatgt tggtttttgg tttgtttata gttttttcgt ttttattata gggtcgttag 111300 ttattttttt agtttatcgc gtgttttttt ttttttttta ttttcgattt tttaataata 111360 gtagattttt ttttaaatat ttttttgttt agatttcggg ttttacgtat gttgttttta 111420 gaaatgtatt ttagtttttt gcgaggagtt agtaaggttg ttcggtgttt ttttttatgg 111480 atgggaagtt ttgtcgggga ttaggattcg gatttggaga ttttgaggag cgtgttggtt 111540 agtgtttgtt ttgaggttcg ggatagagtt gttaggtata ggtagtatcg gtgtgagggt 111600 ttagtttttc ggataagttt ttttttgttt gtttttagat ttgttattgt atatataggc 111660 ggtgattatt tttgatttgt ttgggtagag aagttatttt tttttttttt ttcgttttat 111720 tgtttattag gggaaatgtt ataagtattt aaaaaatgta aaaaaaaaaa aaaaaaaaaa 111780 aaagcgttta atattagggg ttatttggtt taggtggagt ttttattaat tacggggttt 111840 tttgtgttgt ggttttaagg cgggtagtcg atggtttttg ttcgagttaa tatgagttgt 111900 agtttaatta taggggacgg tgattttagg gagtagagtt taggtttcgg ttatagttgt 111960 atttaggagt tagttgtttt ttagatttgt agagttaggg gagaggtttg gaggatcggt 112020 attgaatgat atgatttaaa gcgcgttaag ttgggttgga ggtgacggta gagttatagt 112080 ggttatagag tttttacgtg aatttatacg gatttgtttg gtttaggttt tgttgaattt 112140 tagggtgagg aggatttggt ttttattttt aaagatatga agaggttgat aaagaagagt 112200 tataggtaaa agggggtggt gggtgtgttg tgtaggaggg gtcgtaattg gacgtagaag 112260 attttagaag gggtaattag agagaggtag tatttttaga agacgggttg tttggttgtt 112320 ttaaatagtt tagggtgtga ttgaggggat tttcggattt agtcggggtt ttttttgttt 112380 tgagataacg tattgggaaa ttttattaag tttatttaag aatttgaaaa gttttttgga 112440 aatttagcgg gtagggcggg tttttgggag gatttttggt atatcgcgag agttagatat 112500 agcgaggggg ttttatattt ttgtttagaa gttttacggt agaggggtag aagtttaggg 112560 aggagtaggc gttgagatta gaggggttta taagagaggg gtttggggta gggggtagtt 112620 gttgagaagt ttaggaaacg gcgtttgttt ttggggaagt gaagttttgg gaatagggtt 112680 ggtgaagggg ggcgggaagg gggaggtggg ggtggagggt taggttagat taggtatttt 112740 ttttagtagt agatttatga gtttttggaa tttgtttata gaagtgataa gtgttttgtt 112800 tttagtttcg tttatatatt tatttattaa gtgtggtagg gatagtcgtt ttttattatt 112860 tattttggga tttggattta agtggaggtt tttggagggg tagatttagg ggaaagggtt 112920 tttttagaag tagtcgttat ttagaggatt tgagatgaga attttattac gtttttatta 112980 gatagaggag attcgcggtg ttttcgagtt tggtttttta ttttttattt agtagcgttt 113040 ttttcgttta ttttaagttt agaatatttt gtttttttta agattagttg tcgtagtgga 113100 ttgaatagtg atttttaaaa gatatgttag agttttagtt ttcggatttg tgaatgtgat 113160 aggagttgga atagggtttt tgtagatgta ataaaggatt ttaagaggag agtattttgg 113220 atttagggtg ggttttaaat gtaatgataa gtatttttac gagatataga gatatagaga 113280 aaaggttatg tgaagacgga gtagggagtg gcgtgacgta tttatatgtt taggagtatt 113340 cgggagttat tagaagttgg gagagaggtt tgggtcggag tttttcgtag aggttttaaa 113400 ggattagttt ggtcgatatt ttgattttgg atttttggtt tttagaatta tttttagttt 113460 ttaaagttcg tggggttttg ttgtagtagt tttagtaaat tgttacgggg gttttttttt 113520 tttgttaagt ttggtattta aagtttttta gttatttggg gttaattata ttgattttgg 113580 gatttttagg ttattcgtgt gttttatttt tttgtttaat ttttagtgtt tgtgtggtta 113640 tagttttttt ttcgtgatat gagttttttg ggtttttgag tgtttatttg ttttgtattg 113700 aaggttgaag ttaaattttg gagagaattg attttttttg tgggtagggt aggtattgtg 113760 tttttagtat agttagaggg tattggttga aatgtgtttt tgtaaagtgt tttttttatg 113820 ttcgtatttt ttttttaagt ggggaagtta gagaggtttt ttcgattttt tttttagttt 113880 tttggggtag gaagtttgtg gttatttgtt cgtaaggatt aggtggatag ataattagtt 113940 ttttttaggt tatattttat taatagaggg ttttttaatt ttgttggtgg tttatgagag 114000 aaggaaaaat tgaaggagtt gtttatagta aattttaaat ttttgtgtta gagaggttta 114060 tggttgagta aggtattttt atttttattg ttttgagttg ttaatttagt ttagtttagt 114120 attgtgattt ttgatttgtt tgtgggttac gggagtttgg tttgttaatt agtatttttt 114180 agatatttat tttgtgaagt ttttagtggt tgagtgtttt ttcgtttttt tcggatagcg 114240 tgggttatag gggatattgg gtaggaagat agttaagttt ttattgttta gaaattgttt 114300 gggtttattg tagtaatagg gatttattta ttagtatgag gtttttttgt aggaggggtg 114360 ggggtaggag ggagtttgtg gggtataggg ttgtaggagg agttattttt ttttttatta 114420 aatcgtaggt tttagttaag ttatttttag tatggttgtt tgcgtgggaa gtttatagtt 114480 gagggattgt ttgtacgtgg tatgtaggag ttataagcgt tatttatatt ttatttcggg 114540 ttaggtagat gatttttttg gttttagttt tttgatgagg aataggaagg gttggatcga 114600 aagatttttt ttagttcgga tatggaatga ttttacgagg gttacggtga ggtttgtttt 114660 agtttcgtat attagttcgg gttagtagtt tttaaaggta tagtcgtagg ggttttggag 114720 tagggataag gaggattagt ttattttatt tttttgggta gaggttaagg attttgtttt 114780 tggtttatat tttttgtggt taaaaatgta gaagtaagta gtgttggtag aggtatttag 114840 atttttgggt aaagtagggg ttttatttga tattttaggt ttggagtacg agaaaattag 114900 tttaggtttt aggttttttg attgttagcg attagggaat gtgatatttt tcggtttttg 114960 tttttttatt ttttaatttt agggggagat taggttgggt gatgtgtttt tttttttgat 115020 agtaaatttt tatttatttt tatttttatt tttgttttaa gagggggttt tttatggtcg 115080 ggcgtagtgg tttacgtttg taattttgga attttgggag gtcgagatgg atggattatt 115140 tgaggatagg agtttgagat tagtttggtt aatatggtga aattttgttt ttattaaaaa 115200 atatgtgagt tggtaatttt aagtttttag tagttttcga atggaggttt tttttttgta 115260 ggatttttaa attttataaa tatgagtgtt tgtaatttag ttatttagga ggttgaggta 115320 tgagaattat ttgaatttgg gaggtagagg ttgtagtgaa ttaagaacgt gttatcgtta 115380 ttttagtttg ggatatagtg aaattttgtt aaaaaaaaaa aaaaaaaaag gtgggggttt 115440 ttttatgttg tttaggttgg ttttaaattt ttgggtttaa ggaatttttt tgttttagtt 115500 ttttagagtg ttgggattac gggtacgagt ttatgaattt taaaaaataa tatttattgt 115560 tttgtttttg attgtaaaag gaatttaggt ataaagtcga aaatttgtaa aatgtataaa 115620 aataaaggga aaaaatttat aaatttataa tttaggtaat ttttattaat attttgataa 115680 atgttttttt attttttatt ggggagtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg 115740 tgtgtgtgtg tttaaatagg tttatatagt gatgatgttg ggtgtttttt tttatgtggc 115800 gttatgtggt tgaggttttt atatattttg ggttcgtttt ttcgattttt ttgtagtttt 115860 gatgttttga ttttagatat gttatttttg gttcggattg tttaggagaa ttatttttgg 115920 attttgttaa aaaatggatt gttggttttt aatttttggt ggttttggtt taggagggtt 115980 gggtaagttt gggtatttcg gagtgttttt ggggcgttgt aggtgtgaat ttttgttttt 116040 ttgaagattt ataagtttta ttttttttat tttttttttt tttttcgaga attttataag 116100 aggaaagttt ttattcggag gttgttaggg attcggagtt gttagtttat agttttattt 116160 tgtttttatt ttttcgggag ttatttaagg ataatgttta gttttagttg ttaagtttta 116220 gttttagggt tagttatata ttgaaggata tgtagaagtc gtcgtgtgtt gggtattgtt 116280 gaggataaag gtttgaatga taagcgggaa taaagttata aggttttaaa atttgttcga 116340 ggttttatag ttagggtttc ggaaatttat gaaaaaagtt agtttaatat tttgttacgg 116400 aatataggta ggagagggag tagtttttag ttagttttta gttagttttt cgttagtttt 116460 tttgcgaatt attttatttc gggttatagt tagggtagtc gtcgtttttt tttttgttcg 116520 atagtttttg agggtaggag ttagtttgtt tattattgtt ttttttttat tagggtttgg 116580 tattttgttt ggtatgtagt agaagtttaa gaagggttta ttgtgtttat tttgtaatag 116640 ttaatgtgta tgagtgttta ttatatttga agatagtgat ttatttttgt ttttattgta 116700 tagatgggaa attgaggtat tgagaggttg atgatttttt tatattgtcg tgtgggtaag 116760 ggtaaggtta gatgtgagtc ggtacgttgg gttatcgcgt tttttgttta tatttcgttt 116820 tgggtttggg aaggttattt tcggagattt ttacgatgtt gatatttcgt ttagtttttt 116880 cgtgtatttt tttttacgtt ttttagttat ttaaagtatt agttaggtag tattgttatt 116940 ttggttttgt aaatttagtt attgagtgga agagtagtta ggttgaagtg gggtagaggt 117000 agttttcgtt agattttagg gtcgggattt ttagttattt ttatttttta aggattagta 117060 gatagagatt tttatcgtgt ttagttaggg gttagggaat aggtttttat agtgggggag 117120 tgatggatgg atgtaggtgc ggattgggag gattcgggtc ggttttttag cgttggagtt 117180 ttagtagttt aatttatttt gttgggtttt cgtggggatt aaaagatatt ttgtatataa 117240 agtattagtt tagggtttgg tatttaggag gtgtttaatt aaaggaaatg gttatgaaaa 117300 ataataagga gaagtttagt tataggaggt gtttgtgggt aaggagagaa tagttggaag 117360 ggtttggatt tgggttagag ataaagaatg taagagggag ggagggagag aaggagggag 117420 ggagagaaag agggagggaa agaaagaggg agggagagag ggagggtagg gtaggtaata 117480 gttggtttta gggtagttgt gtgtaggagt ttgttttatt atttaaatat taggagagat 117540 gtaaatattt gagtgaggtt tttttagttt ggttttgttg tggttatagt tagggttgga 117600 gaaagagttt tttttttatt agggttttcg ttttgtgttt tttattttag ttgttttaag 117660 attttatgtt ttcgggttag gagtaggggt ttgagagtag taattaggta gggtagcggg 117720 gttagggagg gatttcgttt ttgtttttat tttttttttt cgtttttgtt tttatttttt 117780 tttttttgta tagtattggg tttgtaaagg tgcgaatgaa ggattttttt ttttattcga 117840 ttttaagggg tttaggcggt taagggtttt ttttgtagtt tagaaaaaaa agtaaagtag 117900 ttttttttga ggttttttgg tggaggttta gggtttaaag ttcgttgtta taaatttgta 117960 gttttttttg tttttttaat agtgtttttt ttttatttgg gttattttat tattttggtt 118020 ttttttagtt ttttaggttt tttggggagg aggatagatg tagagtttgg atttcgtgcg 118080 tagtagggtt tttttaatgt tgcggtgtat ttcgtttggt tgcgggagtt tgttttatgt 118140 tatgatttgt gttggtatta atagtttttt tttttatttt ttatttgagt gtcgagggta 118200 gttgtgttag gtatagatat atagtttttt atatatatta tgagtttgta gaaatggtaa 118260 gagaaggtcg agcgtagtgg tttatatttg taattttagt attttgggaa gttaaggtgg 118320 gcggattatt tgaggtaagg agtttgagat tagtttggtt aataggatga aattttgttt 118380 ttattaaaaa tataaaaaat tagttgggcg tggtggtgcg tgtttggagt tttagttatt 118440 taggaggttg aggtaggaga atcgtttgaa tttaggaggc ggaggatgta gtgagtcgag 118500 attacgttat tgtattgtag tttgggtaat aagagcgaaa ttttgtttta aaaaaaaaga 118560 aagaaagaaa aagaaaaaaa gaaaaggaaa atggtaagag aagttggtta gtattatttg 118620 tttggtaaat ttttatttcg gtttttggtt aggaagtttt tttttaggaa gttttttcgt 118680 tttatttttt tttttgagtt tatgtttaga tttttagtgt ttagaataga gttggttttt 118740 ggggtattta tggatggttg ttggataaat aaataagtta attgtttttt ttatttttag 118800 cgatgttttt ggtttggtag ggtatttagt agtaatgttt ttcgagtgga ttttaaggag 118860 tattttttat cgtgtagttt gtattaggga ttttagtttt ttattttaaa ttaaaggaaa 118920 aaatttaatt ttagtaaata tatagagtat tttatttttt gatttttaat ggggggtaag 118980 aggtagagga tagaggagaa gattattttt ttaggtttgg tttggagtta aaaagatttg 119040 tatgttttta ttgtagataa tatcggtttt tgggggatat agggtagggg tttggtttgt 119100 ttttcgtagg gaaattgttt atttacgtgg aaagcggggt taagggtttt tgtttggaat 119160 tagttttttg tatatggggt ggggggtggg gatagaagga gattttgttt ggattgtatg 119220 gaaatttatt agattgttgg ttgttgattt ggtaggagta gagttatttt tattttttag 119280 ggttttgttt gggggagggg agaggttagg tggttttgtt taggttatat tttttatggt 119340 taggaatgtt ttttttttat tagaaagaaa gatgagatag gtttattttg aattttttgg 119400 atataggaag ggggtttatt tgtggtttag gtggtttttt tttttatatt taaggggttt 119460 tataaggagg tgttaggatt tttaggtttt gttttaggga attgttgttt gtaaaggtta 119520 taggtagaga tagttaggaa tgttttttat gttattggtt atgggttgga ggttgcgaaa 119580 ttaggtatag aattagaaag atttgttata ggttgtaaag ggttttagag agttttagtt 119640 ttttagaggg gtagtattgt agaaggggtg agaaggaaaa attagttttt aggaattgtt 119700 tatttagagt ttatataata tttaggtggt acgagataac ggtttatttt ttattttatt 119760 ttttcgttgt tttttaagat ttgagttttt gggggtgttt ttagtagata gggggatgtg 119820 gggtaattgt ttttttttaa ttgtatattt ggaggtaatt tatatttaga tgattttttc 119880 gaggttgtga ttagagtttg gggtagggga ggggaagcgg gtggatggga aggcgaggga 119940 gattttttta ggaaagtcgt tttaggtgtt tgtaaggttt tatcgtttat atttaaggta 120000 taggtttttg gttttgagga tataggaaat tcgatgttat gtggggagga gggtattgta 120060 atgtatttaa ggttaggttt tttgattttt tggatattgg ataaatgatg gtttttttag 120120 ttggtttaga gatgttagga gtgatagaat gttaaaggtt gtagggggat atttagaaat 120180 tttcgagaaa gaagatggat aaggaaaaat aaaaaaatac gagaagttta gtagagtttg 120240 agtttcgtat tttcggtttt ttttatggtt acgggtaatt ttttggagat ttagttacgg 120300 gagtagtgga ggtaggtatg ggtggggggg ggggcgggtt ttattgttta tggtttcggt 120360 tgatatcgag gttatttttt tgttttttta agtttttggg tattggtagg atttttaaaa 120420 acgataataa atttgaagtt tttagaattg tttgttggtt tagtttaaac ggagtttcgg 120480 ggttttgtag attaaattaa atagtttgag tttagaaatg ttttaggcgt ttgggggtgt 120540 ttaggggtta attggtgggt ttgtttggtt ggagagatga taaatttttt tatttttggg 120600 attgtgtttt agagagtttc ggattttttg gttttataag taatttagag tttttaaatt 120660 tgggaaaaat taagagggtt ttggaaagaa aggtagtgtt tgattatttt tttttagtgg 120720 ttttgttaag ggagagtata ggaatttggt ttttggttgg gtttttggga tgaattaaaa 120780 taaaaagaaa aagtcggggg agggggtggc ggaatcgttc ggggttttag tttaggttat 120840 atattaagga gattttagag gagtaggtta gttttatttt cggtacgatg atggacgggt 120900 atttggttgg ttggtaaagg gaagagatgg taatagtgag gttttgaatt tagtggttaa 120960 gatttatttt tgagtgtgat tttttttgat gtttgggtat gtaagaaatg ggaggtggag 121020 aaaggaggag gagattttag ttttgttttt tcggtattag gttattaggg aatagtattt 121080 tttttttaac gggtaggtag aggttatagg ttgttaggtt gagaagtttt tggtttttat 121140 agataaatgt atagtttgta tatttgtatt attttgggtg atgtttatta cgtacggtta 121200 ttatgtacgt tttttattat taagatagtc gacgagatta ggtggttatt gtgtatcggg 121260 tatcgtggtg attgtttgat attgattttt gggggtttag gttttcggtg ggtttgtttt 121320 tttaggtatt tagttttttt tttatttttt gatatttcgg gtttagtgta ggggtatggg 121380 ggtgtttagt ggatgggttt acgggttggg taagtagtac gtagttttgg tttattagtt 121440 tttggtttta ttattagata agatgagatt gttttagttg ttagtttagt tttgtattat 121500 atttgattgg gtttttgtag aggtttgttg gatgagaatg tttagggtag taggtattat 121560 tttttgggat gtatattttg ttataatcgt tttttaggga aaggttagtt tgtagagtcg 121620 aacgtaggtt gttagcgttt tcgttgtttt tatggttcgg ttatttagta agtgtttatt 121680 ttattgttag cgtttggttt tgtagatggg tatatggttt atttatttgt gatattttag 121740 ggtgggggtg ggggtagatg gtggtaggga agattaggat aattttttag taagaggaat 121800 ttgtagttaa tatgacgtta gtttttagaa tgttagttag gtaggaaaag gggggtttta 121860 tggttgtatt gggagtttga gtatttgtcg ggtttagagg gatttttagg cgggcgttat 121920 tggtattagt gtttgtcgtg ttttttataa ttagtggtga ttatgttgtt cggttttatt 121980 tatatagtgg tattatatag gtttttgttt gagatttttt atttttagat ttgtatattt 122040 aagtatttaa atttatttgt tttttgtaaa tgtttttttt tttcgtttag atgttatatt 122100 agtcgcgata tttattatat tcgtaggagg taggattcgt gtttagcgtt atgggttgta 122160 ttttagagtt ttttagtaat ttttaaagag agttgttttt aattttattt tgtaggtagg 122220 gaaataggcg aagaaattga agaaatcgaa gtcgtttagt tttttaatgg tagagtgagg 122280 gcggtttggg tatttttata ttgttatatt ttttattttt ttaaagtatt gtttttttgg 122340 atgtaaattt tgtttattag ttttatttaa aatttttttg gatagttata gtttatagaa 122400 agtattttta gtttgtagtt atttagttat tgtaggggtg ttttggcgtt tatttttatt 122460 tgtttttttt cggatattta gtttagagaa tttatagttt cgttgtaagg ttgattatag 122520 tgtatttgtt gtttgggtgt tgtgttcgtt tttttttaaa tgaattaatt cgtagtcggg 122580 atagtgggtt tgtttggttt tgggttttga atttaaagag tattaagtta gtgttgttag 122640 tggttgtggg attcgtgtaa gaggtttgtt tttatttttt atggtttttg ttttttatta 122700 taaaagttta aattgtagag aggtagtatt tataggatgt tttgagtttt ggttgaaagg 122760 tagggtttat tacgtaagag gtttattggt attaattagg gataggtttg tatttattat 122820 taagtaacgg ggtttttttt tttagagagg aaagaggtat ttgaattttg ttagcgcgtt 122880 agtttttacg tttcggaggt gttgggattt ttagataaga aggtatattt atatggtttt 122940 ttttatttag aagttcgttt tatagtttgt tttgttttta gaatatagat ttgggggttt 123000 ttttcgggcg atagtggggg ttcgggagaa gtttagatgt tatatagttt tgggatttga 123060 gtacgtgggt tttgggttag attgttttaa taaatattaa ggatttttgg attttttttc 123120 ggtgtgtaaa tttggttata gtaaatatcg ttgagtaaag taggttaata gttggtattt 123180 ggaaaggttt ttgttatata aagattcgag ttgtaatcgt gtttgcgata atagatttgg 123240 tttgaattta cgaaagtata tgtcgttcgt tagtttcgtg tttttattaa ttagaaggga 123300 gaaagaggaa agggttattt tttttgttat tttattacgg gtagtggcgg gtgttgtagt 123360 cgtttggagg ttcgtttgta tagtggaaaa gtagaaaatg agattttaaa aattttatta 123420 gttaaatata aaatattttt tttgttgtta cgtggcggtt tttatagagt tttaaaattt 123480 tgaagttcgg agatttattt tgaaggggga gtaaaggcgg gatgcgggaa gtttgagttt 123540 atggaagata ttgatatttt ttttattttt gggaattttg agtttgaagg attcggtttg 123600 aatagcggaa ggattgaatt tttgtgtaat ttatcggtga tggaatataa agttatggtg 123660 ttttcggttt ttaagacggg agggatgggg aaggttttgg gtgaagggga taggcgggga 123720 aggaaaaggt gaagagaaag gtgtttttta gggagggggt agatgtgttt aggatatggg 123780 atattggtag aattttaatt tcgagtatat atataggttt acggacggtt tttcgtttat 123840 ttgtttttta cgggtgtgtt gtgtcggttt gggtatttgt tttttttttt atgttaggtt 123900 atttgtcgtt tattttgtat attgttatta gttttaagtt ttttagaata ttttgattag 123960 ggttttgtgg tttttgttat aggattttag gtttagacgt ttgttcgatt ggaaaattgt 124020 ttttagagat gtcgtggttt agagttcgtt ttgttttggg gtggtttttg gagttttcgt 124080 tttttagtaa tttatatggt gataggtatt tatattcgtt ggttttagga attttggggt 124140 tattatttta gcgttgtaag gagttggtag tttttttttt attttttcgg tttattttgt 124200 aggaattaag atattaggtg agtcgtttcg ggaaagagat ttgtgttttt acggcgttgt 124260 ttttgcgttt atttttagtt attttagatg tttttcgtgg attagttgta ttttcggcgg 124320 gtatgtttgg tttttcgtag tttggtttat atgattttta taggtaggtt tttttttatg 124380 ttttagtttt ttttttagtt agtttatttt agtttttttt attgttgttg gttgttgttg 124440 gttagaaggt tttttttttt tttgtaattt aatttttatt tttttttaag gttcgttttt 124500 tttatattga tttttttttt gttagttagt ggtgattttt ttttattttg attcggaagt 124560 tgtttgttta tattattttt ggttgggttg aattatattt ttttttttat tttttttaat 124620 tatttttttt ttacgtttgt ttgtttattt aaggttgttt aatttttata tatatatttt 124680 tatatttttt aattatattt taggtttttt gggtattagg gagggttatt tttttatatt 124740 ttaggttagt ttttatgtat atgcgtattt atgtatatat atattttttt acgtttatcg 124800 attcgggtta tttgatggtt ttaagattag aatttttagt aaaattattt aggatatata 124860 agggggagat tgataaatat agggaattag tagattgagg ttttattttt cgagattgag 124920 aaattttttt ttagagttaa aggattgtta attgttgtat taggatggtt ttaatgagtt 124980 tattgttttg gattaaatta tagggttata aaattggttt gggagatagt cgtagaagta 125040 gttttagatg gaggtatatg ggggtaaggg tggagttata tttagagatt taaggaaggg 125100 gtattaataa tttttatagt gtaaatggtg atagttgtat aacgaatata attttaaatt 125160 ttggtttttt ttttcgttat agggttttcg ttgagatacg agagtttttt tttagaaatt 125220 ttattggggg ttcgatattt tttgttagga attgagagta gagatttcga tttcgtaggt 125280 aggaggagag ttttgtataa tatagggttt ttttttataa gggtttattg gaaagtggtt 125340 agatcggtta agtcgtgtta tttggatatt tgggataagg aaggtttttg gaggagcggt 125400 cgtagggagg agttgtaaag aggtaggggt agggaggtta tatttattcg gggattgtag 125460 gaggtttaac ggaatatagt ggatttaggg agattttagt atgagtatgt gtttaaagat 125520 gtttagatga ggaggtgttg tgggggaggg gggcgggaat agtaagtttt tttagttttg 125580 tagatttaga tttttttttt ttttgggaag tagggatgta aagggataga gtttgaaaaa 125640 gggtttttat tattaagttg ataaagtaat tacgatgttt ttagtttata ttttgtatag 125700 cgttagtggt tattggatta taattttttt tcgttttttc gtcgttttat atttttttta 125760 ggtttagttt tgaagaatag ttattggtat tttgtttggc gtttagttaa agttttggtt 125820 ttttaggagg tttcgttttt tttatttaga tagggttgat tttaggtggg tcgtgtgggt 125880 agttgggttt aggatattta gatgttagtt ttggttttgg ttatggagcg gggaggattt 125940 taggttggtt attttttagt ttggtttgat atttggatag tttgtttatt ttaatatagt 126000 tttttttttt ttcggtttat tagagggttt tgtttaagtt agtttaggag ttttttcgag 126060 gggcgggggt tttaggtttc ggtagaggta ggttcgtttt ttagaagttt tgttttagag 126120 cgttggagat tattgtgtga gttttttttt cgtttgttgt atttattttc gcggacgtag 126180 gacgtagagt tttagtatcg gtagttaaga ggacgtagga aagcgtacgt atttataggt 126240 ttagagacgc ggacgttaga tttaggtttg gatagagtag tttcgtaagt tttaatatat 126300 tttgtaaatt tcgaagatag gagagagtta aaatattttt tttgttcgta cgtaggtttt 126360 ttttgttttt tacggttcga ttttgggagg cggatgagga tatttttagg tttggatggg 126420 ggttatggga tattttattt tagattttgt tacgatttgg gttgtgttcg ttcggtgttt 126480 tcggtttacg ggttgtataa tttggcggtt tcgaaattgg cgtgggggag gggagggttg 126540 tttattcgag taggacgcgg ttgtttattt agtcggaggt gaggaacgat ttttttattt 126600 cgttgtcggg tttaagcggg gttcgagagt cgtcggggag agttaaaggg aggggatcga 126660 tggatttttt agagtgaaat tgtgcgtttt ggagagtttc gaggtagttt cgcgagtttt 126720 cgaggaggtc gttgtcgttt ggtaaatata aataataata aaaggaagga aatttaggcg 126780 gtagtgcgta gaacgagtat agggttttgt gagggcgcgt agggtttacg cgggtgtttt 126840 taatagggtt ttttacgtag gcggcgcggg tacggggtcg ggggcgcgcg gcgtttttag 126900 cgggagggcg tttggattag gggtttcgtt tttttttagc gtattttcgt ttttttttag 126960 cgtattttcg tttcgcgtta ggtttattcg tagggttttt tttagtacgt tcgcggtcgt 127020 agtagttagt ttagtattta ttttcgaagt tcgaaatgat tttatttagt tgcgcgttga 127080 tcgcggggtt cgatatgatg gttggtgggt agcgggtcgc gcggagggta gcggcgagga 127140 agcgttttcg gcggggttcg ggttttgcgc gttggttggg gcgtcgcgtt cgcgtttttg 127200 tagtgtagag ttagtcgtcg gaggagtttt taggtttttt ggtttagttg aatgaatggg 127260 ggaggaaggc gggcgtcggt tttttttcgc gcgttgcgtt ttcgtttcgt tttcgttttt 127320 cgggcggatt aggttttcgt attcgtatcg gtttttttgt ttcgtattgg ttgtttcgtt 127380 cgtttgttaa ggttaggttt ggggggttgg ggttcgagtg gtcgttgggg gatagttttg 127440 ggtatacgat cggagcgttt tttttttttt cgtttggttc gcgtttaggg gacggcgaga 127500 gacgcggttt tagttttttt tttcgggcgt ttcgttgcgg ttagatgtgg gcggatgtgg 127560 aggtcgggtt atggcgagga gggcgggcgt ttagagggga agagattttt tttttttttc 127620 gggcgtaggg tttttttgta ggaggttgta tttgggtagt taaataaagt tttttgttat 127680 cgtcgtcgcg cgttttgcgt ttgtaagggt taaacggtag cgtacgcggt tggtaggtag 127740 gatttcggtt tgtgggttta agagtcgagg ggcgtagggc gaatatgcga gttttatggt 127800 attagcgaga ggttattaat ttttatttat cgagggtatt tttgtagtta atatttttat 127860 tacgattatc gtttcggggg ttatcgttgt atttttttgg gtgagttttg gagaaggtat 127920 tgttcgggag aaggggtata gggcggggat ggaatacggt tgttagagaa gttagggacg 127980 ggcgacgttt tttttttttt ataataaggg ttttttgaga gtaggaagta gattttgtta 128040 ggagtagacg ttttcgaagg aaggtgtgaa ggaaggagtt aggtagtgag tgagtagaaa 128100 gggagttgtt ttaagggttt tttttttttt tttgggtttt aatttgaggt ttagtttttt 128160 ttttaggtta gcggttttta tttttaaatt atattattta taaggtaggt agggtcgagg 128220 ggttggggta gatttgggga tttgggttag atatagaatt tgagaagtaa taggttttta 128280 tttttaagaa gggtttttta ggtttgttat ttataagaga gagaggcgtt ttttttattc 128340 gttttggaaa gttagaaatt tatttttgta tgtttttttt gttatttcgt tttttagatt 128400 ttcggttttt gtttagagtt aggggttatg tgagaattta tagtatggaa taatattttt 128460 attttcgaag tagtaggtcg taacgttata attgtatttc ggttttttga atgtgtggtc 128520 ggggagcgtt tgatagttta ttttgggttt gaggtcgttc gttgtttatt tgtttttttt 128580 tatttttttt gaaatatttt aaatgtgtag gagtgttgag attttttagt tattttggag 128640 aggcgggggg tagggggttt tttgcggaaa atgttttagg tttgggtggt tttttaagta 128700 gatgaaatta agtttttttt ttttaagaaa agtaggtatt ttttttttta tgttttggat 128760 attttgaatt atttttaatt aagtgagttt gtggatatgg gaattgtaaa attatagata 128820 ttttagatgc gtgtatattt tcgtcggttt gggagttcgg gttttagaaa tgtagttatt 128880 gttgttatta atagtatttc gtatttttta cgttaggtta gggtatgttt tgtttgaatt 128940 ttagtatttg ggtttatcgg atagtttagt ttttattggg ttatttgttt acgtcgtatt 129000 tggggatttg ggggtttagt atttaagaaa tttagtttaa taatatagtt tttttgggaa 129060 gatgtcgggt tcggtataat agttatttta agttatagta ttattttcga gtgttttttt 129120 aaaaagtatt tggtgagtgt ggatatattt atgtaattgt ttttttttag ggttggtatg 129180 gagttttatt agattagtat agggttagtt aattgtatat tttttatttt tacgtatagt 129240 gtagtaaata tatttagttt tttggggagc gtcgttaggg tgtacgtttt attaaaatgg 129300 gaatttaagg gataatggta ggagagtagt tagaaagtgc gtatgttttc gtgattgtgt 129360 ttagagttta tcggttttag ttttagttat tgttttttta atgtaattat ttagagttat 129420 atgattaggt ttagaaattt ttaggtaagg aggtttttcg agttttttta ggaaatttaa 129480 attagggttt ggttatattt ttagttagga agtttatttt cgtatttaat taattgtttt 129540 aattgtatat tatttatttt tttttttttt ttgtttttag aggagatggg aaatagttgg 129600 gtattatttt ttaagttata attatttttt ttatatttaa ggataattta gttgtttttt 129660 ggtttttttt tttttagttt aaattatttt tttttagttt tttaattata tttcgagttg 129720 ttttttgatt atagttaagg gttgggttta gtttggggtt ttaggatttt aatgaggttt 129780 tattgttata ggatagtgag gaggtttttt attttttttt tttagggttt tagggtttgg 129840 atatatagtt ttagaagggg tattgggtag agaagatgta cgtcggtagt agagaggaaa 129900 ttgagttgaa atttggtaag aataaaagaa ttataaaggt ttgtgtattt agtaaggtgt 129960 atttttttac ggttataaaa gaaggtaaga tcgattgtag gtttggttaa agggatcgtt 130020 tgcgttttta gtgtataacg agatttatag tgggtcggtg atttttttta aaataaagat 130080 atgtttattt ggaattttaa atgtgatttg attttgttta agggtttttg tagaaagaat 130140 ttaggtaagg attttaagat aaggtgggtt ttaaatttaa tgttgtgttt ttttaagaga 130200 tagaaaagaa agtatagaga tatagaaaaa ggttttgtga agatagaggt agagatcgga 130260 gtgatgtagt tataggttaa ggaatatttg gggttattag aagttggaag aggtaaagaa 130320 aggttttttt ttggagtttt tagaggaagt tggttttgtt ggtattttga ttttagattt 130380 ttggttttta gaattgtgag aggatatatt ttttttgtta taagttattt agtttcgata 130440 gttgttatag tagttaggag aaattcgtgt tttattttta tttgtattat gttttgaggt 130500 taaagtttta tatagtaaag atgtttaagt aattataaat tttgtgggta gtttattcgt 130560 ttagtagatt attgttttaa gggaaggggg atggggatag ggaagagagt tataggaaat 130620 ttttgtacgt ttttttggaa atgggaagga gtaggtttgg agagaaattt tataggttag 130680 gtttcgggga aatgaagttt ataaagcgtg ggaacggagt ggggaggaaa tttacgagga 130740 agtagcgttt ggcgtatata tttatattta tgattttttt ttaggtatag tttttatgga 130800 gaggtttagt tggtagggaa gtaaaagagg ttcggagagc gaaggaaggt gaggggtttt 130860 tttttagtaa tattgaggtt ttagacggga tattttatta ggtggtaggt tgtgttttta 130920 tagatagaga ttttttaagg gtagggttta gatggtttta tttttgcgtg gtttgatata 130980 aagtaggttt tttagagttg tcgagttttg ggttcgttag tggtagagtt ttttatagtt 131040 ttttaagttt ttatagtttt ttattttagg aaacggtgtt attatttatt tagttgttta 131100 agttaagttt tcgggtatta ttgttgattt tttttttttt tttattttta gtatttaaat 131160 tatggtgcgt ttttattttt agtttttttg cgaattagtt tgaatttttt ttttttagta 131220 gtgtgttagt taacggttaa taatcggtta tttggggtta gtaaaagtaa taatatttag 131280 tttttcgatt tgtagcgttt gtttattttt gtggtgttaa tatttttgtt ttggttaatt 131340 tttttttttt tttttttttt ttgatagggt tttattttgt tattcggttt ggagtgtagt 131400 ggggtaattt tggtttattg taaattttat tttttaggtt taagtgattt ttttgtttta 131460 gttttttaag tagttcggat tataggtatt cgttattatt tttggttaat ttttgtattt 131520 ttattagaga tgaggattta ttttgttggt taggttggtt ttgaatttag atgatttgtt 131580 tgttttggtt ttttaaagtg ttgggattat aggtatgagt tatcgtgttt agtcggttaa 131640 ttttaagtta tttgtatgat attattggag gtgagattga gaagagatgt ttagttatta 131700 cgaatatagt gtttttatta tataaatata attttaagaa tataatcgta ataggataga 131760 taatagttaa atgttgtaaa aaatttaaga ggtgatgaaa gttgtgtatt tattattttt 131820 tgttttaaat ataattattt ataagtaatt ttttaatgtt ttgtttaatt ttttttttat 131880 aatttgtaat ttaatttata ttgtaaaaat ttattatttt tttaatagag taatgtattt 131940 ttattgtgat aaaatatatg taatataaaa tttattattt ttggttagtt attatggttt 132000 acgtttgtaa ttttagtatt ttggaaggtt aaggtgggtg gattatttga ggttaggagt 132060 ttaagattag tttggttaat atggtgaaat tttgttttta ttaaaaatat aaaaattagt 132120 cgggcgtggt ggtaaacgtt tataatttta gttttttggg aggttgaggt acgagaatcg 132180 tttgaatttg ggaggcggag gttatagtga gttaagatta cgttagtgta ttttagtttg 132240 ggcgatagag cgagatttcg ttttaaaaaa aaaaaaaata aaaataaaaa agataaattt 132300 attattttaa ttaagttttt atgttagtga tattaagtat atttatattg tatatttatt 132360 aatattattt attttcgaaa ttttttttaa ttttttaaat tgaaattttg tttttattaa 132420 ataataattt tttatttttt ttttttttag ttgttggtaa tcgttatttt aattttttta 132480 tgaatttgat tttatataag tgaaattata taatatttgt ttttgtgaga taggtttacg 132540 tagtatgagg tttttaaggt ttattattta aggtttatat gtagtgatag aatttcgttt 132600 tttttgaagg ttgaatgata ttttattgtg tgtatatata ttttgtatat ttattttttt 132660 tatatttgag taattgagag taaagttgtt ataaatatgg gtgtgtaaat atttgtttaa 132720 gtttttgttt ttattatttt attattatta ttttatttat tattagtatt attattattt 132780 tagatagttt tattttgtcg ttcgggttgt agtgtagtgg cgtgatttcg gtttattgta 132840 attttcgttt tttagatcgg agtaattttt ttgttttagt ttttcgagta gttgggatta 132900 taggtattcg ttattatgtt cggttaattt ttgttttttt agtagagatg gggttttatc 132960 gtgttggtta gggtagtttc gaatttttgg ttttaagtga tttatttttt ttagtttttt 133020 aaagtgttgg gattatagac gtgagttatt gcgtttagtt attattttag ttttaaatat 133080 tatagtaatt tttttattgt tttatgagat tttttgagat agtggtttta gggattttat 133140 atatatttgt tcgattttgt gtaatgataa agcgtagttt tttttgtaga atggtagagt 133200 cgggagattt ttgatggggt atgagtttaa aggggtagag gggacgttta gaatatatat 133260 ggatttttta tgtgcgtttt gttagttatt aagtagattt gttttagttt cgatatgttt 133320 aggattatag atagtgtatg gtttttattt gggttaagtt ttcggaattt tttttttttt 133380 tatattattt gtattgggag tagttattag gttgtggatt attaagtttt ttttaggtta 133440 tttgagtttg tattttttta tttagtttga ttgagtcggt gtgtagttat tatattttat 133500 tatatttttt gtttggtcgt tttaatgtaa ttataaggtt ttatttaaag aagtatatga 133560 ttaatttgtt ttttagattt tttagtgatt tttttagttt gttttgtgta gaatatttat 133620 agtaaaattt gattatagcg gtttgagttt ttatttttaa ggtaggggat tttttaaata 133680 aagtattagt gttttaaatt tatgattttt taaggaggtt tttggttttt agtatagtaa 133740 atgttttgtt ttatggtttt tcggtttttt atttttattt tattcgagtt tttcgtttcg 133800 gtatttggga ttgaattagt ttggagtttt ttagttttgt tgtttgttgg ttttgatgat 133860 attattaggg attgtagtat tgtttggatt ttttgttgtt atattttatt gtaataatat 133920 ttaatttgat ggaattttgg gagtaagtgg taggggtagg gatggtggtg gttaggggtt 133980 gtatatatat aggatagaag gattgaagga ttgggtggaa agtatgattt ttttaagatg 134040 attttttttt agtagaattt tggttgtgtt ttttgaatag tatttgttta tttgtatatt 134100 tggtgagttt tgtgattagt aaatttagat gtttgggagg ttattagcgg ttttgttgag 134160 gtataattta gatatgatag tttatgtttt ttttttgatt tttttttttt tatatagttt 134220 tatgattaga gcgttttttt tatttttgtt tttattttag tttcgtaaga tatagtcgtg 134280 aaatggttaa agtttttaat tttttagtat tcgtttgaga ttggagtata aaaatgagat 134340 ggggatatag tattttatgg atattagtga tggaaaaaaa ttttttgatt ttttcgggag 134400 ttttgtaaag ttatattagg ggataagaag gagtggttag tttggtatcg atttagtttt 134460 aaagtagtta gtgattaaag tatatagttg gtattttttt atttttaggg tattaggagg 134520 tttggttaga atttatgtta gttaggagaa ataggttgtt tttggggttt ttggtgtttt 134580 ggttttttta ttgttttttt gaagaaggta ttttgttttg tggggtttga ggttggaggt 134640 aatttgttat cgatgtagtg tagggatgag ggttgagtta ttagtttgtt ttagttttac 134700 gttagtagga ataataggga tttaagtaga gaagaaagta tttattttta aagttattat 134760 agtgattgag gcgacgtggt ttttagggag tttttttttt tgttggtttt ttgtggatcg 134820 cggttttatg ttttaataat gtttttgttt atttcgtaag gtttagtagg tggaaggaaa 134880 gagggtggag gttgggagtg gcggtttggt aattcgggaa gggtagggag taggaatatg 134940 tttttttttt tttgtattcg tttagaaggt tttatagggt ttgttttgtt atttataatt 135000 ttagggagat ttttttttaa tgtttgtttt ataaatgttt atttatttta tatttgaata 135060 tttttagtta tagggagttt agtatttatt tatgttattt attttatttt tggttgttta 135120 aaaaagagga aagagagaga aagaaaagat aggaaagata gagaaagggg gaaagagaga 135180 gagaggaaag aaagaaagag gaaagaataa gataggaagg aaagaaaaag gaagggaacg 135240 gaagggaagg aagagaggga agaaagagag aaagagagag aaagaggtat aaataaggta 135300 ggttttatgg agtagagatt taataaggga gtaaaatata tttgtagtta ggttgtagat 135360 ggatttttat aggagcgtat atttatttta tttttttcgg aatagaaaag tggaaagaag 135420 atgtagcggt gtgggtgggt ggcggttttt tttgggggtt tggaatgtgg ggtattagtt 135480 tttttggttt tgagaaggag attaagatta ttaatattta tagtggagat cgaattatat 135540 aagggttggg gatatcgttt tttttgtatt tttaataaag attcgatgtt ttaattatgg 135600 gaatttgtgg aagaagaaat aaaattggtt ttggggtttt ttagagaatt ggttttttat 135660 ttagtggtgg ttgtgaagaa atttttggag ttagttttag cggtttgggt ttgtatagtt 135720 gagattgttt ttggaagttg agtggaagtg gggagttttt aggtatagtt gggttttgtt 135780 ttttatttta gttagtagtt ttaggatttt tgggtgtttt agagtttttt ttagagggta 135840 aatttagagt atgagggagc ggggagatgt ttaatattgg gggatttttg ttcgtttttg 135900 tttttagttt cgttgatttg aatagggagg ttatgggtgt ttaggggtag aattgtgggt 135960 tggtaagttt ttagttttgg tttttttttg tttttttttt tttattgtta ttgattattt 136020 ttggttatat gttgatattt ttataggatg atggagaaga gagaagagga attttttcgt 136080 tttgtttagt atattttaaa gaggttttag tgtaaaggta tcgacgttta tagttaaatg 136140 tgtgtggggg ttttttagga gtgggacgtt tttatttcgt tttagattgt tatgaatcga 136200 tagaaggttt tatgttatta aatatatttt attaataaat tattttaata tttagtaaaa 136260 aaataaataa aaatgtatgt atttcgtgtt ttgtagtgtt tttatgtcgt attttttttt 136320 gtatttgagt ttcggttcgc gtttttggtt tgtcgttttg ggaatagaac gttttgcgtg 136380 ggaggtagat aggaagcgcg gggtgcgttg gttgggtttt tttagataat ttggtattgt 136440 tttttttaga taatgaaatt ttttttattt tgagtgtttt tggaagttag tcggtagtta 136500 gattaattta aatgaattat ttgttttttt tgtgaagtga ttttagggat ttaatgggtt 136560 tgttattaat atagtttttt tcgtattttg tttttttttt ttattttttt ttttttgtat 136620 gagttattgg ttacgatgat tcggtttagt taagggattt ggttagtttt ggttaggtta 136680 tgtgagagat agtataaagg attaaggttg tcggaattag gttagaggtt gagggttata 136740 cggatttttt ggagtgtttg taattgggga tttttaaggt tgttttttgg ttttggggat 136800 ttgtttattt ggggatagtt ttaagggaga tttttaaaag tagggagtta aaagggtgaa 136860 ttaatataga aatattgagg gttagggaga atttgaagat gggttcggtt gggtatagtg 136920 gtttatgttt gtaattttag tattttggga ggttaaggtg ggcggattat ttgaggttag 136980 gaattcgaga ttagtttggt taatatggtg aaatattatt tttattaaaa atataaaaat 137040 tagtcgggtg tggtggtagg tgtttgtaat tttagttatt taggaggttg aggtaggagg 137100 attgtttgaa cgtaggaggt agaggtggta gtgagttaag attatattat tgtattttag 137160 tttgggtaat agagtgagat tttattttaa aaaaaaaaaa aaaaaaaaaa aaaagatagg 137220 tttaaggttt ggagagttag aagttatttt tttatttttg ggtggtttat tttgagattg 137280 tattacgtta gagaaagttg cgggagtgtt tgtttataat ttataagtaa tattgttttt 137340 tttttttatt agtttttggt tttagtaggt ttttgattcg tgtttttttt agggttttgg 137400 gtttttttaa gttggatttt cggttgttgg tgggatgatt atgtgatttg ttattttttt 137460 gtttatcgtt ttgggtagtt tttgttattt ggtgtatata gagtggagtt tagtaaggtc 137520 ggggtcgtcg attttttgtt agttatattt gttttttttt acgttatttt ttttcgtttt 137580 ggttatgttt aggggtttat atttttttat aagttaggtg ttagattttt gtgtttgttt 137640 tattttgttt tttttgtttg gtgggttttt tatatttttt ttggtttgat ttaggtttga 137700 tttgttttta ggttttagtt tagaggttgt tttttttagg aagttttttt gggatcgtta 137760 gatgaaggga tttttttttg gatttttttt ttatttttat agttttagga atagttttta 137820 atttaggttt tattgagtta gtgtggtatt taggagagtt ataagcgtgt gacgaacgtg 137880 ttgaagtttt tttaaaagtt gaaggagttt tgtgaatata tagtagtatt agtttagatt 137940 gcgaaggtat aggggagtta gtttttttta gtttcgtttg tttttggttt tttttttgag 138000 gaggtgggag ttagttagtt gggattagga ggtgggtttt atggagtaga gatttaataa 138060 gggaataaaa taaattagag aatttttttg ttgtaaggaa tttagataag gagtatttag 138120 ttagaggagg aaggaagaga tcggtagtag attttttttg ttttagtagt tttgtaagtt 138180 agatgggtta attttttagt atagttgttt tttagtatag agaaattttt tatttttagt 138240 aatagggtgg gaatattttt agatagggtt acggttattt tggttatagg gattacggag 138300 tttgagtttt tgtggtttgt tttatttatg tggttataga ttttgagtat atatttggag 138360 ttatagagtt taaagggtag ggtagggtag ggaatttgtt tgattggtga aggttatttt 138420 attatttgga gtataggttt ttgtttttaa atttatatgg agttttcgat acggggtatc 138480 gattttaagg aggtgaatgt ggatatttaa ggttagtgaa tggttaggtg ttaatatatc 138540 gataggtttt tggttttttt tttaatattg agggtaggaa ataaatgggg tttatatggt 138600 gtatatggtt tttagagtta gtaaggtgtg taagattcgg tagttgagaa aattgattat 138660 ttggtcgggc gcggtggttt acgtttgtaa ttttagtatt ttgggaggtc gaggcgggcg 138720 gattacgagg ttaagagatc gagattattt tggttaatac ggtgaaattt tgtttttatt 138780 aaaaatataa aaaattagtc ggacgcggtg gtaggcgttt gtagttttag ttatttcgga 138840 ggttgaggcg ggagaatggc gtgaatttgg gaggcggagt ttgtagtgag tcgagatagc 138900 gttattgtat tttagtttgg gcgaaagagc gagattttat tttaaaaaaa aaaagaaaag 138960 aaaagaaaag aaaattgatt attcgattat gaataagtta gaatatttat ttagaaaaaa 139020 aaaatagttt tgtttaattg gggatttaaa attttaggat ttatgttttt tttttataga 139080 gttatattat ttttttaatg tttattttcg attttatttg tttgttaagt tttaggtatt 139140 tagaatatag tatgatagta agttttgtga tttttatagg tttttttaat ttattttagg 139200 tatagttata tttttagttt tgagtagtag ggagtgatat gtagatggtt atttagatag 139260 agaaagattt ttaaaaggag ggtaggtttt gtttcgtagg tagtatttat tgatatagat 139320 attagtaggt aaatttttta ggaagatttt tattaagaaa gaacgaaaga ggtttagtgc 139380 ggtggtttac gtttgtaatt ttagtatttt gggaggttaa ggcgggtgga ttattttagg 139440 taaggagttc gatattagtt tggttaatgt ggtgaaattt tatttttatt aaaaatataa 139500 aatttagttg gacgtggtgg tgggtatttg taattttagt tatttgggag gttgaggtag 139560 gagaattatt tgattttagg aggtagaggt tgtagtgagt taggattata ttattgtatt 139620 ttagtttggg gggtaataga gagagatttc gttttaaaaa aaaaaaaaaa aaaaaaaagg 139680 atgaaagata aataaggttg aaattggtag gttggtatat ttttaataat ttattttagg 139740 tcgggcgtag tggtataatg ttagtatttt gggaggtcga ggagggtaga ttgcgaggtt 139800 aggagatcga gattattttg gttaatacgg tgaaatttcg tttttattaa aaatataaaa 139860 aattagtcgg gtgtggtggc gggcgtttgt agttttagtt attttggaag tttaggtagg 139920 agaatggtgt gaattaggga ggcggagttt gtagtgagcg gagatcgtat tattttacgt 139980 tagtttgggc gatagagcga gatttcgttt taaaaaaaaa aagaaataaa aaataaaaat 140040 aataaaaaaa aaataattta ttttagtagg gagtaggagg taaggtttga tatgtagtgt 140100 ttgttaattt ttgtggtgta aatatattta ttgtggtaaa ttttaagtta taaataggat 140160 attattaaat atagagttgg gaaaagatat gtatattatt ggataaaacg tttaggtagt 140220 tacggtttat ttttttttgg gaaggggggt atgtttagaa tgttttttat tatggagaat 140280 gattgtggta aatagggttt aattggtagg ttgatttaat taattgttta ttgatgtgat 140340 gtggggtagg tttttgaggt tgtttttatg tttagggaag aaggtggtta tgtggttata 140400 gatttggttt tgggtttgtt tttttttttt ttttttgaga tagagttttg tttttttttt 140460 ttaggttgga gtgtaatggt gtgattttgg tttattgtaa ttttcgtttt ttgggtttaa 140520 gtaatttttt tgttttagtt ttttaagtag ttgggattat aggtgtttat tattatgttt 140580 agttaatttt gtatttgtag tatagatggg gttgttggtt aggttagttt taaatttttg 140640 attttaggtg atttatttat tttggttttt taaagtgtta ggattatagg tatgagttat 140700 tgcgtttatt cgggtttgtt attttgagga tatatttgga gttatgtgtt tatgattttt 140760 tttttatttt aaaattttga ttttatttta ttgtttttag agataggttt tgttttgtta 140820 tttaggttgg agtgtagtgg tgtaattata gtttattgta gtttcgaatt tttaggttta 140880 agcgattttt ttattttagt ttttcgagta gttggggttg ggtttatagg tgttattata 140940 tttagttata ttttatattt ttttgtagag atagggtttt gtaatttgtt taaattggtt 141000 ttaaattttt ggttttaagt aattttttta tttttagttt tataaagtgt tgggattata 141060 gatgttagtt agtgtattta gtagttatta tgattgattg gtgacgtttg ttttagtttt 141120 aggatgaaag agtagtagta ttttagttaa gtatttgtgg tttttgattg gaagacgttt 141180 tttttgtttt ttaagtatag tgtaaatgtt atttttttgg taagtttttt tttaatttta 141240 tttttttttt ggtatagggt ttgttatagt tttgtttata taaagagagt tattagtgta 141300 tgtggtatag atgttagttg tttttttaat atttgagttt tttttttttt atagtaattg 141360 aagttttggt tgtgtatagg gaagtttagt tgaagaatat attgtttagt ttttttgatg 141420 ataggagcgg ttatataatt gggttttggt tagtgggaag gagttgaagt gtttaatttt 141480 taggttatgt ttttaaaaat aaagagggat atttgttttt tttttttttt tttttttttt 141540 tttttttggt tggagtgtag atatgacggt aggagttgga attattttag tttaagagat 141600 ggaagttgtg tgtcgaggat gtattaaagg aatgaattag gttcgggttg ttttgggttt 141660 ttataacgat tgatatttgg attgggacgt gggttcgagt gttgtttagt ttttgatgtt 141720 ttagtttttg ttatatagtt agatggtgtt ttgattaatt taaggtatgg ttattatttt 141780 atttgtttgg tagggtaggg gttttatttt tatacgttga gtttttggta gaatttggtg 141840 taatatatat agttaaagta aaatgaatag gttattttaa ttaaggttta ttttgtgggt 141900 tggttttggt atttggtttt aatttttatt ttattttatt tatttattat ttttgagata 141960 gagttttata tttgttgttt agtttagaga ggagtggtgc gatttcggtt tattgtaatt 142020 tttatttttt aggtttaagt gattttcgtg ttttagtagt tgggtagttg ggtttttttt 142080 gagtagttgg gattataggt gtacgttatt atgtttggtt aatttttgta ttttttgtag 142140 agatggggtt ttattatgtt ggttaggttg gttttgaatt tttgatttta agtgatttat 142200 tcgttttggt tttttaaagt gttgggatta taggtatgag ttatcgtgtt tagttagttt 142260 tggtatttgg aattggaaaa taatagtttg agttttagag gggataaata taaatatgag 142320 gtagaaggaa tagtaagtaa atacgtgttt agagtaggtt gggttgttta tatttttaaa 142380 atatcgttag gtgttgaggt ttgggttttg tgttagattt ttgggtgtag atttcgtggg 142440 gatatttatt gggtagtggg atttttggta agttatatta tttttttgag ttttcgttga 142500 ttaagttgtt tattgagaat aatatttaga ttgaaaggat ttataataat atgtgaaaag 142560 tgtttggttt aaaataggag tttggtaatt ggtagttttt attatttata atatatagtt 142620 taacgttttc gttttatagg aatgaaaata ggatttagat aggtaaaatg atttgttgag 142680 ggtcgtatag tgttaatgat agagttagga ttagggtttg gggttttgat tttttttgta 142740 gtattttggt tttgtgagaa gtggttttgg gtgaatataa ggagtgagga gttggtgaga 142800 aattttgaaa atgaagttgg gtgtggtggt ggatgtttgc ggttttagtt atttaggagg 142860 ttgaggtagg aggattgttt gagttcggga gttggaggtt gtagtgtgtt atgattgtat 142920 tatcgtattt tagtttaggt gatttagtaa gattttattt tagaaaagga aaggaaagga 142980 gaggggaggg gaagggaggg aatttttgat agtgatttta gagataatta ggatgatttg 143040 aaattatttt gaaatgtatt aaaaaataaa aataaaatgg atttatggtt aggcgaagga 143100 gggatagatg gacggtgagg tgataaagta ggtgtagttt ggtgttagtg gtagaattta 143160 ggtgatggtt gaatgtgttt tttgtaaaat gtttttaatt tgattatgtg ttttgaatat 143220 ttttataata gaatggaggg aagagaaagg taagagggag ttattgtagt tgttgtagta 143280 ggagtagatt ttaaaatatt atgtattaga tttttagttt tgtttttgtg gatgtgtttt 143340 tgtttttttt tttgggattt aaggatattt aatgagcgta tgtgttttta agtttttttg 143400 tttttttatt tgtttttata tttggaagat tttataggtg gcgtgggtta gttttttatt 143460 ttgttttttg tgtttttagt gtatgataga tattgagtga gtgttagttt tttttttcga 143520 tattttgttt gtttgtttag agaggttttt ttatagttta gttattaggt tgatgttttt 143580 ggacgtttgg tcgatagttt ttttagttgt gttttagtga tttggtaggt gttttgagtt 143640 ataaataagg ttattagtgg atgtttttaa agtttttttt attacggcgt tttttttttt 143700 tttattaata gttcgttatg atagttagtt tgtatgagtt tttttttagg gttgtgtttt 143760 ttgaggttgt ttagcgtttg gtttgttaga gtttattaga tagggtgttt atttttttta 143820 ggtttgagtt tttatttaga gaattattta tagaaggata atggagaaag gtagttgggg 143880 tattaaatgg agtgtgtttg tatgtggggg gggaggggag ggggagggaa agtaggaaga 143940 gaagatataa gaggagaaat aagaataaga ggaaatatag aaggaggagg agtagttttt 144000 tttatggggg tggattttgt gtttagtttt ttattaagga tattatattt attatttcgt 144060 ttggttttta cgaatatttt taaggtcgtt tttttttggt ttttattttt ttattaggaa 144120 gcggaggtat agagtgagaa agagttgttt aaggttttta ggtagtttac ggagttattg 144180 ggagttatat ttaattcgtt taattttacg tttttgtttt tagttattat aataaattat 144240 taaggtttta tagttatagg agtttagttc ggagttttta tcgggttttt taaggtaggg 144300 agatggggtt ggaggttatg ttaggtgtac ggtgtttaga gttgtttagg aagtttcgcg 144360 gtgcgggttg ggtattaggt agtgtttgta ggatggagaa atgaatgagg ttgagatata 144420 gtgtcgtttt ttttaaacgt gatttttttt gagtttttgt gattggttat ttgagagggt 144480 agttttggtt ttttggcgtt tatgttcggg tttagagatg ttttttttag ttaggttttt 144540 ttttgaggat ggaaatttag aattttatta taggaggaag agttgggagt attttatttt 144600 tttttttttt ttgagacgga gtttcgtttt gtcgtttagg ttggagtgta gtgacgcgat 144660 ttcggtttat tgtaagtttc gttttttggg tttacgttat ttttttgttt tagtttttcg 144720 agtagttggg attataggta ttcgttatta cgttcggtta attttttgta tttttagtag 144780 agacggggtt ttatcgtgtt agttaggatg gtttcgattt tttgattttg tgattcgttt 144840 atttcggttt tttaaagtgt tgggattata ggtgtgagtt atcgcgttcg gttagggagt 144900 atttttaaga tttttgcgga gggttgttta ggtttaagtt ttttattatg gaaggttttt 144960 tagatgcggt agttacggtg tatgggttga gggtttttat ttattaagaa gtaggagtat 145020 ttgatgtata tttagtttac gatttttatt tatttggggg ttgtgtttgt agttacgtga 145080 tataagggaa tagttatagt agtgggttat aaagagagtg tgggttaatg tgtaggggta 145140 gaattttgat agttttttat gggttggtag tagggagggg tatatttgta taaattttat 145200 acgtatagtt ttttatatat atgtggttga taattattta tatatttaag acgggatttg 145260 gcgtatagtt tattagtaat aggcgttggt aatttttagt tgtttttttg ttgcggcgta 145320 gatattattt aaggtgggat ggagagagtt attgttttta aggttatata ttttaaaggg 145380 agatgttggg ttacggaatg aaaataggag gattagttag agttattggt tttgagttat 145440 ataatgggat atataggttt atttatttta tatttttatt gagtaattat aacgagttaa 145500 gttgtataga ttatttaaat aatcggtacg tagaaaagta ttttaatttt tttttggttt 145560 tgacgtgatg ggaagaattt ggatttttgg agttatagag ttggatggaa attttggttt 145620 agttaattat tggttggggg agttcgggta agtgatttaa ggtttttgag tttgtttttt 145680 tgtaaaagag tagtgttcgg gtttgttacg ttaggttagg gtaagatgat tgaagagtaa 145740 gcgtttagta tcggttaggg gttaacgttt ttaaggacgt aaagtgtaat aagtaggcgt 145800 tacgattgta tcgtttttta ttgtttgtgg taaatatata agtaaagatg gtttcgcgtt 145860 tgcgttgggg gaggtaggga attggtttta ggaggacgtt ggttttttta gttgtttttt 145920 ttaaagtttt ttgggaggag aaatgattta ttttagttgt tgggagtttt aatttataag 145980 taggtttgtt tattcggtag cggtcgtatg taggtaggag gggtttcggt agtttttaag 146040 agtgaggggt cgtttagttt ttttttagtt ggaaaggagg ttttaggttg ggtaggagta 146100 tttggggaaa tttagttttt ggagttaggt tatattaggg agatgaggtt gttagaagtt 146160 tttttggtgt ttatagtaaa atataattaa agtgggattt agattttaat tagtttaagg 146220 tttgatttat attagaggga aattagcgtt tgtcgtatga gtgagcgttt atgtgcgtgt 146280 aaggtagaga tagattttgg gtaagttttt ttattttttt acgtttgttt ttttatttat 146340 aaaacggggt aatattattt attttatagg gttgttatga aataaatatg tattaatatt 146400 tgtaaagtgt tgagaatagt atttggtata aaataagagc gatagatttg ttaaataagt 146460 aaaaaataag atataagttt aaagtagagt ttggtatatc gtgagtatta agagttgtgt 146520 tttttgattt tttttttttg tggagatttt tttattagaa gtgggaggga ttgtcgaggt 146580 tggagttttg ttttagggat ttttgtgggg agttttttag tttagaggga tttgttttac 146640 ggattatatt tgtttcgggt tttcgtgttt ttgtgtatgt gtgtatatat gtgtgtatat 146700 atatgtaatg tgcgtgtgtg tatttttatg gatttgtgat aatttgtata tatatgttta 146760 gaatttattt gatatagtgt tttattaaga tgttggagtt tcgatgaatg gattgcgggg 146820 ttgagatatt gtttttatag gaagttgttt tagtagtaag ttttttggtt tttatagata 146880 attaaaaaga atggagtttg tttttatttt ttgttttaaa aatgatgtat agtgtgtggg 146940 gtttgatgtt ggaggttttt ttagtagata tatttttaat aatattatat tttgaaattt 147000 aagttgtcgt aaaataagat aagtaaagat ggtattggta gggatttttg aggttttttt 147060 tatgtatttt tgaataattt ttatatggtt tttgtttgaa tgtttttagg tatggggaat 147120 ttattatttt gtgaaatagt ttgttttatc gtttttaagt gaatattgtg agaaaaatat 147180 ttttttttgt aaagagttaa gttttattcg ttagtatttt ttaggtattt ggtattagtt 147240 ttatattttg ggggaattta aaataaatgt ttttttttta ttagataatt tattaattat 147300 ttggagatag tggttgtagt tttttgtttt atgtagttat tttatttagt ttttttttgg 147360 aatttttgac gtgaatataa gtttttttgt tacgtaggtt ttttttttgg gttttttatt 147420 tatttgcgta tattttggag aggtcgttcg ttttgtgggt gagatttatt gtgggttgaa 147480 ttgtgttttt ttaaaagata tatgtaagtt ttgatttttt agtatttatg aatgtgattt 147540 tatatggata tagggttttt gaagatgtaa ttgggttatt tgagggtata ttgaattaga 147600 gtgggtttta aatttaatga taggtgtttt tataagatag aggtaggttg ggtatagtag 147660 tttatgtttt taattttagt gttttgggag gtaaagtttt attgtttgag cgtaggagtt 147720 tgagattagt ttgggttttc gtttttataa aaaaattaaa aaattagtta ggtatggtgg 147780 cgtgcgtttg tgttttagtt atttggaagg ttgaggtggg aggattgttt gagtttggga 147840 ggttgaggtt gtagtgagtt atgattacgt tattgtattt tagtttggag gatagaatga 147900 gaatttgttt ttaaaaataa attaaaaaga taatagagag ggtagtttgg atagagatat 147960 aagaagagat atagggtgaa ggttaggtgg ggggtaggtc gagttgtaag tcgaggaata 148020 ttaggggttg ttggtcgtcg tagagttcgg agaaaggtat gggatagttt ttttcggaat 148080 ttttaggagg aatgaatttt tagatatttc ggtttgggat ttttggtttt agaaatttta 148140 gggaagatat ttcggatgtt tttgtttttg tttttgtttt tgtttttgag acggagtttt 148200 gttttgttat ttaggttgga gtgtaatggc gcgatttcgg tttattgtaa tttttatttt 148260 taaggtttat gttatttttt tgttttagtt ttttgagtag ttgggattat aggtatttat 148320 tattacgttc ggttaatttt tttttttttt ttgtattttt agtagagacg gggttttatt 148380 atgttagtta ggatggtttc gattttttga tttcgtgatt taatcgtttc ggttttttaa 148440 agtgttggga ttataggtat gagttatcgt acgtggtcga tttcggatgt tttgagttat 148500 tttatttgtg gttttttgtt atgatagtcg taggatagta atatagggtt ttagtagggt 148560 ggttcggtaa gggttttttt tttacggtag tttttatttt gttttatttg tagggttatt 148620 tagatgttta tttcggtttt ggttagtaag tgttagtgta tttttttacg tttagtagta 148680 agggtagtat cgttgttgat taagtatttg ttatgtcggg gtttttgtgt ggttttgggg 148740 tttttttttt ttgtttatat ttggtagttt agtttttttt tttgtatttt atttgatgtc 148800 ggggttttgg gtaagtttgg gggatttgtg ttttatttta tagatttttt agttgatttt 148860 attagttttt gtatagggtt cgtttgaagg gtcgttgggt tgggcgttaa ttagagtttt 148920 tagtagtagt tttttcggtt ttttgatttt ggtttatgtt ttaggggtag ggtttttaag 148980 ggttttgggg tcgtttttga ggttagtttt tttgttgatc gtagtttata tagaggaggg 149040 tttaattttg agtgtggtcg ttcgtgattt tgagagatgt ttagagttgt agacgtgttt 149100 tttaagtttt ttagagttcg ggataggagt tatttaatgt ttttagtgtt ataggtaaaa 149160 tttgtttttt ttaatataaa ttgtttttag ttttatttaa tgtttttttt aacgagtagt 149220 aataaaaata tggttttttg ttaaaggtgg ggtttatagt tttttagaat tcggtttttt 149280 gttaggttta ggtataattt ataggagtgt tcgtttttga ttcgtgtgtg tgtgtgtgtg 149340 tgtgtgtgtg tgtgtgtgtg tgtgttgtgt gtacgcgtat atgtgtttgc gtaagttttt 149400 ttatgtgtag ttttgggaag ggtggagagg tttacggaaa ttttttttgg tatttagtaa 149460 gttagaaaaa aggaaaatga gatttgtgta tatatgtgta agtgtatata tagtatatag 149520 gtatatatat atatatattt agtatatatt atataggttt atacgtgtat atatgtgtag 149580 gtatatatta tataggttta tacgtgtata tatatggggg tatatagtat ataggtatat 149640 ataggtatat atattttttt gtaggaaagt ttttttttgt tttttatttt gtagggtttt 149700 taggttttat gaaataagat tgaattttgg aagtttgata aaaggtttgt ttggagtatt 149760 ttggttattt ttattagttt ttttagttgt ggaaggtatg tttcgtggta tttatttatt 149820 ttttgttttt atttttattt tcgttttcgt tttttttttt ttgttttttt agtttatatg 149880 ttgtttgttt taattttaat ttttgtattt ggacgggaat tatttttttt gtagaagggt 149940 gtaatgtatg tggggatata tatatatata tatatatata tattgtattg gaggagagaa 150000 gagaggtaga gtttttttta gatttagagt tttagcgagt gacgggattt tttttagaga 150060 atacgtgtag aagtttgcgt tattggaaga agatattatt ttgatttata tttttttttt 150120 tttttttcgt tttttttata gagaaggaaa ggttttagta aatagtggtt atgtgggttt 150180 tttgtatgtt attggtagtt ttttagttag gattattttt tttttatttt tggaagtata 150240 agaatagaga gaagggtgag tttttgtttt tgggggtttt tttttgtatt tttttggagt 150300 taattttagg gttgtgggtt gtataggaag gagggtttaa taggtttttc gtttaatttt 150360 gtttttttag tgaggagtcg atttattttg tttgtaaaag atgttggttg ggatttgatg 150420 ttgggtaatt tgaggagaag agaaggggga taggggttga ggttaggttt ttggttttga 150480 aatagttata atttttgggg tagagtttaa gggtgttagg ttggagattt tatattcggt 150540 tagttggtag ttattatttt ggtttagtta gtggtttagg gtattatagt tatttagatt 150600 aggaatttta tttttttgga ttgtattaat gaggaaggtt gagtttgtag gttttatata 150660 tttatggtaa ttttaaggta gagaggttat tgttaattga gggttacggg taggagtttt 150720 gtgagtttat tagtaagttt ggaagattaa ggtttttggt tatagagagt agttgttatt 150780 tggttaattt tgtagaaaat attatagttt tggataaaat atttgaaaga ataaaataat 150840 aatagtttgg agttagtata gaatatttta agtaggtaga agttggagta gagtttatat 150900 ttgatagagg ggaataaaat tagataagtt tttggttttt ggaggttttt ttgtttagag 150960 gtaggtattg agtaattaaa tttggataaa aagttttaaa agtatttagg gaaaaataat 151020 atgtggttta taggggaata gttagatgaa tgttgatttt ttgatagaaa taacggaggt 151080 taaagatatt ggaattttat attttaaagt tttgaaagaa aaaattgata atttagaatt 151140 ttataattag tgaaattatg gtttaagaat gatagtaggt tgggtatagt ggtttatatt 151200 tataatttta gtattttagg aggttaaagt aggtagatta tttgaggtta ggagttcgag 151260 attagtttgg ttattatggt gaaattttat ttttattaaa aatataaaaa ttagttgggt 151320 atgatggtat atgtttgtag ttttagttat ttgggaggtt gaggtaggag aatcgtttga 151380 gttcgggagg agaaggttgg tgagttgaga ttgggtagga gttttgaaat tatattattg 151440 tattgtagtt tgtggggaga tagagtgaga ttttgtttta aaaataaaaa taaaaataaa 151500 aaaagaaaga atgatagtaa aataaagatt tgtagataag tgaaaatgaa agggaattag 151560 ttgtttgtaa atttgtatta taaaaatcgt gaagtaagtt ttttaagatt atgggaaatg 151620 agattagatg ggaatttagt tttttaggaa ggaatgaaga gtataggata tagtaaatat 151680 atgggtaaat agaaaagatt ttgttttatt tttaattttt ttaaaatgta tggggttgtt 151740 taaagtaaaa atttttttat tgtattgttt agtttataat gtgtatggat gtagtaaata 151800 tttaataatt attatatata ggatggaaag tggtaaatga atttatagga ttgtttagtt 151860 tttatatttt ttttttatga agaaaaataa tgttaatttt aagtagattg tgaaaagtta 151920 agaatgtgta atagaattta taaagtaatt attaaaatag taatataaag agatataatt 151980 aaaaagttaa aataggtcgg gtttagtggt ttacgtttgt aattttagta ttttgggagg 152040 ttagggtggg cggatcgttt gaggttagga gttcgaggtt agtttggtta gtatggtgaa 152100 atttcgtttt tattaaaaat ataaaaatta gtcggtcgtg gtggtaggcg tttgtaattt 152160 tagtatatta gggaagttga ggtaggagaa ttatttgaat ttaggaggta gaggttgtag 152220 tgagttaaga ttatgttatt gtattttagt ttgggtaata gagtgagatt ttgttttaaa 152280 aaaaaaaaaa aaaaaaaaat ataaattaaa atagaatttt aaaaaatatt taattaatat 152340 aaaagaagtt aagaaagtaa gatgaaagaa ataaatatta aagagtaagg tagtagtttt 152400 aaatttagtt atatttataa ttatgttaaa tagaaatagt ttgaatattt taattaaaag 152460 gcggaggttg ttagaatgaa taaaatagta agatttaatt atatattatt tataaaagat 152520 gttgttttag tataaatata ggttgaaatt ttttgtttgg aaaaagatat attgatgttg 152580 tttgaatgat gatggagtta tgttttgata aatttattat aagtggaaaa taaatattat 152640 tttaaaaatg tatttaatat atttaattta tcgaatattt tagtttagtt tagtttattt 152700 taatatgatt agaatattta ttttagttta tagttgagta aaattaataa atataaagtt 152760 tattttataa taaagtgttg attattttat gtaagttatt gaatattgta ttgaaagtga 152820 gaaatataat ggttttatat atatttaaag tatagttttt attgtatata tattacgttc 152880 gtattatggt aaagttgaaa aattgtaagt taaattatta taagtttttt tataagtttt 152940 tttagttttt ttatgtattt taaatagtat gtttaagaag gttggagagg ttatataaat 153000 attaataaag ttgagtttaa gataaaatta ttacgagata aaggaatata tttattatgg 153060 ttaaatgatt agtttatcga gatattatta taattataaa tgtgtatgta tttaattaaa 153120 ggagttttaa aatatatgat ataaaatttg aaagaattaa agggagaaat gggtaatttt 153180 ataattatag gtggagattt tttttttttt tttttgagac ggagttttat ttttgttgtt 153240 taggttggag tataatggtg taatttcggt ttattgtaat ttttattttt tgggtttaag 153300 cgattttttt gttttagttt ttcgagtagt tgggattata ggagtttgtt attacgttta 153360 gttaattttt gtatttttag tagagataag gttttattat gttgtttagg ttggttttaa 153420 atttttgatt ttaggtgatt tattcgtttt ggttttttga agtgttggga ttataggtgt 153480 gagttattgc gtttggatgt atagttggag attttaatat tattttagtt tatttaggat 153540 gttaaaataa aatgttttag gttgggtaat ttataaatag attgtagtgt ttatagtttt 153600 agaggttggg aagtttaaaa ttagggtgtt tagtgtttgg tgagagttag ttttttgttt 153660 tagagatgtt ttttttttgt tgtgttttta tatggtagaa gggattaatt ttatttacga 153720 tgattttgtt tttatgagtt aatatttttt tgatgtttta atttttaata ttattgtatt 153780 agagattaag ttttaatata tgaattttgg gggatataaa taggtaggtt atagtaaata 153840 ttattttttt aatatttgag aaataagtat tagataattt gaagaatatt ggtaattagt 153900 aattgattta attagtagtt ataaagtttt atatttagga agtttagaat atatatatat 153960 attttttttt taagtgaaaa tagtgtattt attaagatat atattttggg ttataagttt 154020 taaattttaa aagtatgtaa aatatgtttg tttggttaaa gtaagattaa attagaaatt 154080 aatagtttta agatatttag aggagttttg attatttgta aattaaataa tatattttta 154140 aataatttat gagttaaaga ggaaattata agaaaaattt tataatattt taaatgaaat 154200 gataatgaaa atatagtata ttaaaatacg taggttgaag ttagtgttta gagggaaatt 154260 gtaagtgttt atattagaaa agaagtaaaa aaaaaaaaaa aaaaaaaaaa aaaaagattt 154320 aaggatttgt tttaagaatt tggaaaaatg ggttaggtgt agtgtagttt acgtttgtaa 154380 ttttagtatt ttgggaggtt aaggtaggtg gattatttga gattaggagt ttaagattag 154440 tttggttaat atggtgaaat tttgttttta ttaaaaatat aaaaattagt tgggtatggt 154500 gggtattttt agttatttag aaggttgagg taggagaatg gtttgaattc gggaggtgga 154560 ggttgtagtg agtttagatt atgttattgt attttagttt gggtaataga gtaggatgtt 154620 tttttaaaat aaaataaaat aaaataaaat aaaataaaat aataaaaaaa ataaagaatt 154680 tggaaaaata tgttagttat ttatgtattg ttttttaatt ttgtatatat tttgttaggt 154740 ttcgtttcgt gatattggat cgaggtttta tgagtttttt tttttggtta aatatagtta 154800 tgttaggttt tatttatagg ggataatatt gtggggagtt gttaggtttt gttgaggtag 154860 tagttttttt ttttggtttt agggtttttt ttttttttga aggtatagtt gttagtggcg 154920 tgtgtttagt ggggtttgtt ttgtattgag tttttttagt attttagttt tagtttaatg 154980 ggattttagt aaatttttta gatatttagt ttttgtttat ttatattttt tagtaggttt 155040 ttcggttatt tagtaagttg attttgtaga tttatttttt ttatattttt tggtaagaat 155100 ttttttgtta ttagtaggtt gtaggttttt gtggtagtta tatatttttt aataaggttt 155160 gaacgtaaga cgtggtaagg tgtggaggac gtttcgagtt tttggttttt tttttattaa 155220 ttttagtggt agtaattgtt tttgtgtgtt tgtatatatg ttttaaagta tttattatag 155280 aaaatttatt attttaatta tttttaggtg tgtagtttgg tggtatgaag tatatttata 155340 ttgttgtgta attattatta ttatttattt tattttttta aattgtaatt ttatttttat 155400 taaatattaa ttttttattt attttttttt tttttagttt ttggtaattt ttattttatt 155460 ttttgttttt ttgaatttga ttattttagg gattttataa aagtgaaatt atatagtatt 155520 tgttttttta tgtttggttt ttgttattta gtatgttttt aaggtttatt tatgttatag 155580 tatgtgttag aatttttttt tttttttttt tttttttttt ttttgaggta gttttgtttt 155640 gtcgtttaag ttggagtgta gtggtatggt ttcggtttat tgtaattttt atttttttag 155700 tttaagcgat ttttttgttt tagttttttt agtagttggg attataggta tatgttttta 155760 tgtttggtta atttttgtat ttttagtaga gatagggttt cgttatgttg gttaggttag 155820 ttttaaattt ttgattttaa gtgatttgtt tatttcggtt ttttaaagcg ttgggattat 155880 aggcgtgagt tattatattt ggtttttttt ttttttttaa ggtagaataa tattttattg 155940 tatagatgga ttatattttg tttgtttatt tattcgttgg tggatatttg ggttgtttgt 156000 attttttggt tatgggaaaa gtgttgttat aaataagaat gtagtatatt tgtttaagtt 156060 tttgttgtta gttttttgga gtatatattt agaagtggaa ttattggatg ttatggttat 156120 tttgagttta attttttgag taattgttat atttttttta tagtagttgt attattttat 156180 atttttatta gtagtgtacg gggttttaat ttttttatat ttttgttaat atttgttgtt 156240 atttatgttt tggttaatag ttattttaaa gggtgtgaaa ttatatttta ttgtggtttt 156300 gatttttatt tttttgatga ttagtgatat tgcgtatttt tttttgtgtt ttttggttat 156360 tggtatgttt tttgtggaaa aatgtttgtt tattgggttg tttttttttg ttttgtggtt 156420 tagttgtagg agttttttat atattttgga tattagtttt ttatcggata tacgattttt 156480 aaatattttt ttttattttg tggatttttt ttttacgtta ttggtagtat tttttgatgt 156540 ataaaagttt taagttttgg tgaagtttaa tttattattt attttttttg ttgtattttc 156600 ggtgttatat ttaagaaagt attgttaatt ttaatgttac gaagtttttt ttttatgttt 156660 ttttttaaag tagttgtttt ttatatttgt tttttttata ttttttagag tttttttgta 156720 taaggtaaaa taaattttat ttttttattt ttatttataa tatttagtgt tttagttttg 156780 atattagatg tgtggttttt tttcgtcgat ttttaagtaa ttttttaata tttagtagtt 156840 tttaattggg tgttttgtaa tttagtttaa ttttgatatt aattagagtt agtgtagatt 156900 ttataggtta agggttttat tttataagat tgtttttaat tttagagatt agtcgtaagt 156960 ggtaagatat taggttattt ataatttttg tttgatttgg ttataaattt gaggttttta 157020 taattttttt tttaggttta ataatttgtt tgagtgattt atagaattta ggaaattagt 157080 ttatttaaaa ttgttgattt attataaatg atattttaaa ggatataaat gaatagttaa 157140 ttggaagaga tgtataagaa aggtatgaag gaagcggtat ggagttttta cgggagggta 157200 tattgttttt ttagtatttg taggtattta ataatttgaa attttataaa ttttattttt 157260 ttgggttttt agggaggttt tattatataa gtatgatatg aaatttttgg ttattgatga 157320 ttaatttaat ttttattttt ttttgtttcg taggaggtgg atgggaaagg ttgtaagttt 157380 tagtttttta attataaggt tgggtttttt ggtaattagt ttttattttt aggttgttta 157440 ggagttttta gttattagtc gtttttttag taaataaaaa gatatttatt attttggaga 157500 ttttaagagt tttaggagtt atatgttaaa taaagttggg ggatagagat tagatagata 157560 gatagataga tagatagata gatagataga tagatagata gatagatata ttgatttttg 157620 agatagagtt tttttttgtt atttaggttg gagtgtagta gtgtaatttc ggtttattat 157680 aacgtttgtt ttttcgggtt taaattattt ttttatttta attttttaag tagttggaat 157740 cgtaggtata tatcgttacg ttaggataat tttttgtatt tttggtagat atgaggtttt 157800 attatgttgt ttaggttggt tttaaatttt tgagtttaag ggattcgttt gttttagttt 157860 tttaaagtgt tgggattata aatatgagtt attgtatcga gtttagttta aatatatttt 157920 ttttatatta taatgttatt tttttgtgat ttttttaata gttaattatt ttttatagtt 157980 aagaatattt tatattataa gttgttattt aaattgtcgg tgtggttttt gttttttgat 158040 tgggttttga ttaatgcgtt gaagtaagta taaggaagga agtaatgaag ataatagaga 158100 aatttaagga aatggatatt agaaaagggg agtttaatgt tggtttttta aaaagattta 158160 gattgataat tttttagtta ggttgttgat gagagggaga tggcgaatat aaagttataa 158220 taaaaggaat gaagtgtttt ttttacggat tttatcgata ttatagtgat aaggaatata 158280 ggtatatttt attttattgt gttttataga tattgtattt tttataaatt gaaggttcgt 158340 ggtagttttg tattaagtaa gtttgttggt attatttttt taataatatg ttaatattgt 158400 gtttttgtgt aggagtttga tgatttttga aatagtttaa atttttttat tattattata 158460 tttgttatgg tgatttgtga tttttttttt tttttttttt tttttgtttt tttttttttg 158520 agatagagtt ttgttttgtt tggagtgtag cggcgcgatt tcggtttatt gtaagtttcg 158580 tttttcgggt ttacgttatt tttttgtttt agtttttcga gtagttggga ttataggtat 158640 ttattattac gttcggttat ttttttcgta tttttagtag agacggggtt ttatcgtgtt 158700 agttaggatg gttttaattt tttgatttta tgatttgttc gtttcggttt tttaaagtgt 158760 tgggattata ggcgtgagtt attgcgttcg gttttttttt tttttttttg agatggagtt 158820 tcgttttgtt gtttaggttg gagtgtagtg gagtgtagtg gtgtgatttc ggtttattgt 158880 aatttttatt ttttaggttt aagcgatttt tttgttttag tttttttagt agttgggatt 158940 ataggtattc gttattacgt ttggttaatt ttggtatttt tagtagagac gaggttttat 159000 tatgttggtt aggttggttt taaatttttg attttaggtg atttatttgt ttcggttttt 159060 taaagtgttg ggattatagg tatgggttat cgcgtttagt gattagtgat ttttaatgtt 159120 attattgtag ttgtttttgg ggtatgacga gttatattta gataagatag tgaatttatt 159180 taataaacgt tgtatgtttt gattgtttta ttgattggtt gtttttcgtt tttttttttt 159240 ttgtttaggt atttttattt tttgagattt aataatattg aaattaggtt aattaataat 159300 tttataatgg tttttaagtg tttaagtgaa aggaagagtt attcgttttt tattttaaat 159360 taaaagttag aaatgattaa gttgagtgag gaaggcgtgt cgaaagttaa gataggtaaa 159420 agtgagattt tttatgttaa atagttagtt aagttgtgaa tgttaagaaa aagttattga 159480 aagaaattaa aagtgcgatt ttagtgtata tatgaagaag aagaaagtaa aatagtttta 159540 atgttgatat gaagaaagtt tgagtggttt ggatagaaga ttaaattagt tataatattt 159600 ttttaaataa aagtttaatt tagggtaaag ttttaatttt ttttaatggt atgaaggtta 159660 agagaagtga ggaagttgga gaaggaaagt ttgaggttag tagaggttag gttatgaagt 159720 ttaaggaaag aagttatttt tataatgtaa aagtgtaagg tgaagtagta ggtgttgatg 159780 gagaagcggt agtaagttat ttagaagatt tagtttagag tattgatgaa ggtggttata 159840 ttaagtaata gaattttagt atagatgttt tattttttat tggaagaaga tgttatttag 159900 gatttttata gttagagggg agaagttaat gtttgttttt aaagttttaa aggataggtt 159960 gatttttatg agaggttaac gtagttgttg atcgtaagtt aaagttaata tttattgatc 160020 gttttaaaaa ttttagggtt tttaagaatt ttgttaaatt tattttgttt atgttttaga 160080 aatggaataa taggttttat ttgatagtat atttgtttat agtatggttt attgaatatt 160140 aaaaatttat tgaggtttgg tgcggtaatt tacgtttgta attttagtat ttttgaaggt 160200 tggggcgggg ggattatttg aggttaggag ttcgagatta gtttggttaa tatggtgaaa 160260 tcgtattttt attaaaaata taaaaattat ttaggtatgg tgttatacgt ttgtaatttt 160320 agttatttgg gaggttgagg taggagaatc gtttgagttt aggaggcgga ggttgtagtg 160380 agtcgagatc gtgttattgt attttagttt gggtaataga gggagatttt gttttaattt 160440 gaaaaaaaat aaaaaaataa aaaagggtta agtacggtgg tttatagttg taattttagt 160500 attttgggag gttaaggtag gtaaattatt tgagtttagg agtttaagat tagtttggtt 160560 aatatggtgg tgaaatttta tttttattaa aaatataaaa attagttagg tatggtagtg 160620 tatatttgta gttttagtta tttaggaggt tgaggtagga gaattatttg aatttgggag 160680 gcggaggttg cggtgagttg agatagcgtt gttgtatttt agtttaggta ataaagcgag 160740 attttgtttt aattaaaaaa taataataaa aaaaaaataa atagggttcg gtgtagtggt 160800 ttatgtttgt agttttaatg ttttgagagg ttgaggtagg tggattattt gaggttagga 160860 gttcgagatt agtttggtta atatggtgaa attttgtttt tataaaaaat ataaaaatta 160920 gttaagtatg gtggtgtgtg tttgtaattt taattattta ggaggttgag gtataagaat 160980 tatttgaatt cgggaggtag aggttataat gagtcgagat tatgttatcg tattttattt 161040 tgggtgatat agcgagattt tattaaaaaa aaaaaaaaat tattgagatt tattgtttag 161100 gaaaaaagaa tttttttaaa atattattgt ttattgataa tgtattttgt gatttaagag 161160 ttttgacgga gatgtatgta aagatgaatg ttgtttttat gtttgttaat gtaatattta 161220 ttttgtagtt tatggagaag ggataaattt gatttttaag ttttattatt taagaaatat 161280 attttataaa gtagtatttg ttatagttag tgattttttt aatggatttg ggtaaagtaa 161340 attgaaaatt ttttggaaag gattttttat tttagatgtt attaagaata tttgtgattt 161400 ataagaagag gttgaaatat taatattaat aggagtttgg aagaagttga ttttaatttt 161460 tatggatgag cggtttaaga ttttagtaga ggaagttatt gtagatgtgg tggaaatagt 161520 agagaattag aattagaagt ggagtttgga gatgggattg gattgttgta attttatgat 161580 taaatttgaa tagatgagga gttgtttttt atggatgagt agataaagtg gtttttggag 161640 atgggattta ttttaggcga agatgttgtg aatattgttg aaatgataat aaaagattta 161700 gaatattata ttaatttatt tgattaattc gtggttaggg ttgaaagaat tgattttaat 161760 tttgaaggaa gttttattgt gggtaagatg ttattaaata taatgcgtgt tatagaaaaa 161820 ttttttatga aagaaagagt taatttatgt taaaaatttt agttaagaaa ttgtcggtta 161880 ggtgtagtgg tttacgtttg taattttagt attttgggag gttaaggtag gtggattatt 161940 tgaggttagg agtttgagat tagtttggtt aataaggtga aattttgttt ttattaaaaa 162000 tataaaaatt agttaggcgt ggtggtaggt atttgtagtt ttagttattc gggaggttga 162060 ggtaggagaa ttgtttgaat tcgggaggta gaggttgtag tgagttgaaa tcgtgttatt 162120 gtattttagt ttgggtaata gagtaagatt ttgttttaaa aaaaaagaaa aagaaaaaag 162180 aaataaagaa attgttgtta tagttatttt taatttttag taattattat ttggttagta 162240 gttattaata ttgaggtaga ttttttatta agaaaaagat tatggtttgt tgaaggttta 162300 gatgattatt agtatttttt agtaaaaaga tataatgatt ttatatattt taatagatta 162360 tagtatagtg taaatataat tttttttttt tttttttgag atggagtttc gttttgttat 162420 ttagtttgga gtatagtggt gtgattttag tttatcgtaa tttttatttt ttaggttcga 162480 gtaatttttt tattttagtt ttttaagtag ttgggattat aggtatgtgt tattatattt 162540 agttaatttt tgtattttta atagagatga ggttttatta tgttggttag gttgttttta 162600 aatttttaat tttaaatgat tcgtttattt tggtttttta aagggttagg attataggta 162660 tgagttatta tgtttggttt aaatataatt tttatatgta ttgggaaatt aaaaagtttg 162720 tgtgacgtgt tttattgtaa tatttgtttt attgtcgagg tttggaagta aattttaggt 162780 atgtttgtat tacgaataat tttaaatgag taaatttaat aatttatttg aaagggataa 162840 atttttttaa agtataattt attaaaagta agataagggg aagtaaaaaa atttgaataa 162900 ttttttttat atattaaatt gaatttgtga ttaaaaataa ataattattt tttttagtag 162960 aaaattttag gtttagacgg tttttttggt ggattttatt aaatatttaa ggaagaaata 163020 atattaattt tatgaaaata tagaaaataa agagaaggga atatttttaa attaatttta 163080 tgaagttaaa atgaggttga taaagatatt atcgaaataa attaataaat aaagaaaata 163140 ttatattaat attttttatg aattaatacg taaaaatttt taaaaattgg gtaaattaaa 163200 tttagtaata tataaaaagg atgatatttt ataagtaagt tggatttttt ttagaaatgt 163260 aaggttggtt taatattaaa aaattaggtt tgtatagtgg tttatatttg taattttagt 163320 attttgggag gtagaggtgg gagtattgtt taagtttaag aattgtagat tagtttgagt 163380 aatataatga gattttattt gtataaaaaa ttttaaaaat taaaaattag tttggtatgg 163440 tggtatgtgt ttatagtttt tgttatttag gaggttgagg tgggaggatt gtttaagttt 163500 aggagtttag gttgtagtga gttacgatgg tattattgtg ttatagtttg ggtaagagtg 163560 agattttgtt tttttaaaaa aaaaaaaaaa aaaaacgggg ggtaaaaatt aattattgta 163620 atttatttta ttaaacgaat aaaagataaa ataatgatta tttttataga tgtagaaaaa 163680 gtatttatta aaattatatt tatttatgtt aaaaaatttt agtaaattaa gaatagaagg 163740 gaattttttt aatttgataa aggttatata tgataaattt aaagttaata ttataagttt 163800 ggtataggta aggatgttta ttaattatta ttatttaata ttgaattggt agttttaatt 163860 agtgtaataa agtaagaaaa aaaaataagg tattaagatt agaaagaagt aaaattatgt 163920 atttaaattt taaaagattt ataaaattat tattagagta ataaatgatt ttggaaaaga 163980 ttataggata taagatttat atataaaaat ttattgtatt tttatatatt agtagtaaat 164040 aattaaaaat gaaatttaaa atttatttta gtttaaaata gtgttaaaag taaaattttt 164100 aggaataaat ttaataaatg gtatgtaaga tttttttttt gaaaattata aaataatgta 164160 attttgtaga gatttttttt tagtagagaa ataaaagaaa tataaaagga tttttaaaac 164220 ggagatatat tatttatata aaagatttaa tattgttaaa atgttaattt ttttttaatt 164280 gatttataga tttaatataa ttttaattaa aatttatatt gtatttttgt agatattaat 164340 aagttatttt ttaaatttat aaggaaattt aaaggattta gaatatttaa agtaatattt 164400 tagatatttg agagatttta tattaagatt tattgtaaag ttatattaat taagatgtgg 164460 tattagtaaa ggaatggata aaatattaag aaaatataat agtgttttaa tatagggttt 164520 atatgtatat agtatatata ttaatatagg attatatata tagttaatat aggatttata 164580 tgtatatagt atatatatta atataggatt atatatatag ttaatatagg atttatatgt 164640 atatatgtat atatattaat ataggattat atatatagtt aatacggggt ttatatgtat 164700 atatgtatat atattaatat aggattatat atatatatat agttaatata gggtttatat 164760 gtatatatgt atatatatta atataggatt atatatatag ttaatatagg gtttatatgt 164820 atatatgtat atatattaat ataggattat atatatagtt aatatagggt ttatatgtat 164880 atatgtatat atattaatat aggattatat atatagttaa tatagggttt atatgtatat 164940 atgtatatat attaatatag gattatatat atagttaata tggggtttat atgtatatat 165000 gtatatatat taatatagga ttatatatat agttaatata gggtttatat gtatatatgt 165060 atatatatta atataggatt atatatatag ttaatatagg gtttatatgt atatatgtat 165120 atatattaat ataagattat atatatagtt aatatggggt ttatatgtat atatgtatat 165180 atattaatat aggattatat atatagttaa tacggggttt atatgtatat atgtatatat 165240 attaatatag gattatatat atagttaata tggggtttat atgtatatat gtatatatat 165300 taatatagga ttatatatat agttaatacg gggtttatat gtatatatgt atatatatta 165360 atataggatt atatatatag ttaatatagg gtttatatgt ataaatgtat atatattaat 165420 ataggattat atatatagtt aatatagggt ttatatgtat atatgtatat atattaatat 165480 aggattatat atatagttaa tatagggttg atatgtatat attaatatag gattatatat 165540 atagttaata tagggttaat atgtatatac gtatatatat taatatagga ttatatatat 165600 agttaatata gggtttatat gtatatacgt atatatatta atatagggtt atatatatag 165660 ttaatgattt ttagtaaagg tgttaggtaa tttaatagag taaggtatgt ttttttaata 165720 aacggtgtta gaattggata tgagtataga aaaataagaa ttaattttga ttttaaatta 165780 aatataaaaa ttgatttaaa atggattata taatattttg acggttataa taggttaaaa 165840 aatgtaaaaa tttaaaaaat taaaaaataa aaggaattat agaatatata attataaaat 165900 ttttagaaaa taagagaatt ttttttgatt ttagtgtagg taaagatttt ttttataggt 165960 tataaaaatt ataaatcgaa attggaaaaa gttgataaat tggattttat gaaaataaaa 166020 tatttttgtt tattaaataa tattattaag aaaattaaaa ggaaaggagt aatgtggaaa 166080 aaaaaattta tgatatatat atttgataaa ggatttatat ttagaatata taaaaaatat 166140 atgaaataat attttttttt tttttttttt ttgagataga gttttgtttt gttatttagg 166200 ttggagtgta gtggtgtaat ttcggtttat tgtaagtttc gttttttagg tttatattat 166260 ttttttgttt cggtttttcg attatttggg attataggcg ttcgttatta cgttcggtta 166320 attttttgta tttttagtag agatggggtt ttatcgtgtt agttaggatg gttttgattt 166380 tttgatttcg tgatttgttc gtttcggttt tttaaagtgt tgggattata ggcgtgagtt 166440 attgtgttcg gttaattttt tttttaaatg agatttatgg ggaaatagtt aaatgaagaa 166500 ataataaagt agtaataaaa taaaatttaa gttttatttt attgtgtagt tgtaggataa 166560 agagtagaag tttgtagttg gggaataagg tgtttatttt tttaagtatt ataaaatgaa 166620 ggttttagaa attattcgat tttgaaataa tataatttta aaaagaagta agacgtggat 166680 agataatttt ataaaggaaa atacgtaaat gattaataag gattttggaa aattgtgcga 166740 ttttataagt tattaagaaa atataaaata aaagttttaa aaaaaaatga agtttggaat 166800 aattgaataa atatataaaa cgataataaa atgaattttg attttttatt ttatattata 166860 tgtaaaagtt aatttataaa agttatataa ttttaagttt tttaaaggaa aatataaata 166920 tttttgtaat ttggtagggt aggtaaaggt tttttataaa gaatatagag agagaattat 166980 aaagaaagga gtttgttaaa ttagatttta taaaaattaa agtgatatat ttttgtttat 167040 tggaaaatat tattaagaaa atgaataggt cgggtatggt ggtttatgtt tgtaaaatcg 167100 gtttttgggg aggtagaggt aggaggatag tttgagttta ggagttttag atttgtttgg 167160 gtaatatagc gagattttgt ttttgaaaaa ggaaagaaaa tgaataggta agttatagat 167220 tggaataaaa tatttgtaaa atacgtattt gataaaagat tagtatttag aagaaaaagt 167280 taagtaattt aattttaaaa tgagtaatag atttgaaaag atattttata aaggaaaaat 167340 atatgaagag ttaattatga aaatgtgttt aatcgtatta gttattaggt taaagtaaat 167400 taaagttata atgagatgat attattatac gtttattaga atgattaaga ttttatagag 167460 tgatagtatt aaatgttggt taggatgtgg agtaattaga attcgtattt attgttggtg 167520 ggagtgtgaa atggaagggt tattttggga aaagatttgg tagtttttta taaaattaaa 167580 tgtatattta ttttatattt attttaggtg tttttataga ataaatgaac gtttatatgt 167640 atagaaaaat ttgtataaga agaattagcg taataggttt atttataaga gtttttagat 167700 ggaaatagtt aggggttttt taataagaga atgattaaaa atttatagaa tgtttatata 167760 gtggacgtta tttagtaata aaatagaata aatcgttggt atttgtagta atatgggtag 167820 ttttaagaaa tatttaaatt ggtaaaatta tttcgtggtg gaaaaaaagt ataattgtgg 167880 ttgttttggg gaaggtgggg attgtgatgt atttggaggg gtatgaggaa tttattgggg 167940 tgatagtgat gttttatgtt ttggttaggt tgggatatac gtggatattt ttgttaaaat 168000 ttaaagaacg gaacgtttta tatttgtgta ttttagggta tatatatttt attttaaaga 168060 aaaataaaaa taattataga taaatgtcgg attttagtta atgaaatgta aattgaggtg 168120 ttgataggat gttgtgtgtt gatttttgta gtttatttta agtgtattaa aattagcgtg 168180 gatgttggtg gttagaggga tttgtggtga agtaaatagt aaaatggttg ttgtggaatt 168240 taggtggtag gtgtatgggt gtttatttta gaatttttta tggttttttt tttgtggttt 168300 tgttttgttt tgtttttgag atagggtttt gttttgtcgt ttaggttgga gtgtattggt 168360 ataattttag tttattgtag ttttaatttt ttaggtttaa gtaatttttt tattttaatt 168420 tttcgagtag ttgggatttt aagtttgtat tattatgttt gattaatttt ttgtattttt 168480 tatagagatg ggattttatt atattgttcg ggttggtttt gaatttttgg gtttaagtga 168540 tttttttatt ttaatttttt aaagtgttgg gattatagtt atgagttatt atatttagtt 168600 tttttttatt ttttttatgt ttgaaaagtt ttacggtaaa aagttggaaa aatgtaaaaa 168660 agattgaaat ttattaatta aaaataggaa aaataaaata aaagagatgg taggagatta 168720 tttttttttt ttttaattta gtttttaatt tttttttttt tcgtttagtt aggataggaa 168780 ttttaagggt tcgggttttt cgtgtttgtg cggggaagga ggtattttcg tgtttgtgcg 168840 ggggttggtt atttgttttt cggtgtattt tttgtatttt attttttttc gttcgtagtg 168900 agtagttata gttggcggaa attatattta ggtagttttt gtttataaat ttagtgaaaa 168960 tgtaaatttc gtaggagttg gattttcgag agtttgcggc gttatttgtt ggaggaaagg 169020 ttttttgtat tcgagttttt tttttttttt tcgttgttat tcgttttttt gtttaggttg 169080 ggcgggtttt ttttttgtaa tttcggggta ttggtgtacg ggaaatgttt agtgttttat 169140 aatttttttt tatttatatt ttaatattta gtttttagtg gatatcgttt tcgttcgata 169200 aatatattat ataggtatag tttaagatta tttattttag gaggagtata agttttagtg 169260 tttattattt tagttttttt tttttttttt ttgacgtagt gatataggtt taggatattg 169320 aagatttttg attttataaa tatgttgaag ttaattattt tgaagttgta gtttttatta 169380 ttattattat tttttatttt ttgtaaagat aaagttttgt tatgttgttt agtttggttt 169440 ggaatttttg gatttaattg atttttttgt ttcggttttt taaagttttg ggattgtagg 169500 tgtgagttat tgtatttagt ttgaagtcgt agttttttaa ttattgttaa tagtaatatt 169560 tatttttttg tgagtagtag ggtttgttgg tatggttgat agttttgtat tattgtatcg 169620 aatttgttgt ttgggatttt aggtgagttt cgatttttag ttggagggat aagttgtgtg 169680 gggttgggta gggtgaattg cgggagatta agtttagatt gagggttata agttatatga 169740 gtattggggt taggtaggga tagtgaagga gatagtgtaa ttttgaggaa agataacgtt 169800 atagaatgga gaggtttagg ttcggggttt ttttttgttg tcggataggt atgtttgtgt 169860 ttttttttta gttttcgtga tggttaagtt atgtgttttt tgagaggtaa gcgaggtttt 169920 tgatagtagg ttttaggttt taattaaatt gtttgttttg tagggtgagt tgtataggtg 169980 tttttatttt cgattttttt gaatttttgt tgtttttaag ttttatttat tttttttagg 170040 tgaatagaaa tattgtttag gggagaacgg aggaagaatt taggaaaggt tgttcgagag 170100 tttggttgag tttacgttat cgttaagagt agcgttaaaa tttaggagtt ggtgagatta 170160 tggtttaggg tttatattaa tatgaggggg tgttagtttt atgattaatg agtttttgtt 170220 ttattatttt ttgttattta tattttgagg gttatagtta gtacgtgaat tggagttggt 170280 tttcggtatt ttttttttta tattagtttt ataatgtgag gtgggggttc gtttttagag 170340 gtattcggag tagtaggtgt tttaagaggg ggaagttttt tcgaagtttt tttttattta 170400 cggtatagga cgtagagggg atagagtatt aggaatattt agcgattata ggggtttgtt 170460 tcgaaggaga ggaggtagga ggtagggaga gtggttggga ggttagtttt ggagtgttta 170520 ttttttattt cgagggagag gaaggaagta gaaggtgagt atagggagtt ttagttgggg 170580 atggagcggg ggttgtagtt cgattgtgtt gtttggagcg ggggtatgga ttgtagtttt 170640 tatttatttg tttggttagt tcgaagttat tttaagtttg gagattttat ttgttttgtt 170700 tatttttttt agggatggtg tttaaatttc gaagttttgg ttggtgttgt aaatatggga 170760 gggaggtttt gttttatttt agttttaaga gttagttaag aatgttttgg atatttgaat 170820 tttgtttcga gttagaggtt gggaagaaat ttgaaggatg gtgggacggt ggatagtagt 170880 ttttaggtat taggtattag ggtttttgtt tggggatggg ggtattagta ggtgttaagt 170940 gtattatatt agggtttatt atgtttttgt ttagagattt agtattttac gaaataggaa 171000 ggaacgaggg atgagcgtgt tttttttttt aatattttag tttttgtttt gaggttgtta 171060 ggtatttaat ttttttagga tttaaattat tttggtttta tttacggtta agtgtattaa 171120 attatagtta ggattattgg gtttagatat taaaagcgtt ttttttaaag tcggtagtta 171180 ttagggtagt atagggtagt gtaaggttgg gtagggtcgg ttatttgtta gtatttagtg 171240 gtttttgttg gatgttgacg ggggtagtta ggtaggtggg tttatttagt aattaaagag 171300 attttttttt tttaattttt tttttaaaga gattttgatt tttttttttt agttgtaggg 171360 tttgtagtag tttttttttt agtaggtttt tttgtttgtt tttggttatt tttagtagtt 171420 atagggtatt gaggttttat tatagtgaga ataaaattaa gtttttatta gggtttttaa 171480 ggttcggtac gatttggttt tgtttgtcgt attggtgtta ttatggttcg tttttgaaaa 171540 tatattttag ttatttttat tttttttagg ttttagtttc gggtttttat atttgttgtt 171600 ttttttgtta ggttgttttt tttttggatt ttggtttggt tgggtttttt tggttattat 171660 agttttagtt tagtgttatt atttagaaag ggtttttatt aattttttcg ttatatatat 171720 agatatgtat ttttagtaat ttgtttttag tttttttata gtttttattt aaaattattt 171780 atggatttgt ttatttgtgg attgtttttt agttttaatt gttaagtaat aagcgattag 171840 cgattgtgtt tttgttgttt tttattatag gttaagtatt taagagaggg gttgtatata 171900 gtaggtttta ataaatattt attagacggg ttaggtacgg tggtttatgt ttgtaatttt 171960 agtattttgg gaggttaagt tgggtggatt atttgaggtt aggagatcgg gattagtttg 172020 attaatatgg tgaaatttta tttttattaa aaatataaaa attaattagg tatggtggcg 172080 gacgtttgtt attttagtta tttgggaggt tgaggtagga gaatcgtttg aatttgggag 172140 gcggaggttg tagtgaggcg agatggcgtt attgtatttt agtttgggtg acggagtgag 172200 atttcgtatt aaataataat aataaaatat ttgttagaag aattaaagta gtttgtttgt 172260 gtttaatagg aatttaagag tataagatga atttaattaa aggatatata tagtaggtat 172320 tttatagttg atatttgttg gtggagggag attaggaaag tggggagagg tagtgtttgg 172380 gtatggggat attttgggta tggggacgtt ttggatatag ggatatattg ggtacgggga 172440 tattttgggt ataggacgtt ttgggaacgg ggatattttg ggtacgggga tattttgggt 172500 atggggatgt tttggatata gggatatttt gggtacgggg aaattttggg tatggggatg 172560 ttttggatat agggatatat taggtacggg gatattttgg gtatggggat gttttggata 172620 tagggatata ttgggtacgg ggaaattttg agtatcggga tgttttaggt acggggacgt 172680 tttttgttat ttgaaatttc gtagttttat tatattcgtt tgttttagta aatcggttta 172740 aagagtattt ttaagttttt atggtaaagt tttagagtta gtgttttttc gttgatttcg 172800 agggtgtgtt gtttatttag tgtttaagtt agagtttttt tatttagaaa aaaaaagagg 172860 agggtggttt tacggatgga ggtatgaggg cgtttatagg tagagggagt tttcgggttg 172920 agatttgcgt tattttttgt tttaatttta aggcgtagtt tggagtttaa attagttttt 172980 aaacgtgggt cgttggttaa gaggaatttt tttatttacg attttttttt atatttagtt 173040 tttattgttt agagtatgtt agttttgttt gttttggttt ttaggatttt tttagggatt 173100 tttaggtttt aagttagggt gggtttgaat taaggtagtt ttagaattta tgttaatgtt 173160 tttgttagtg ggagattttg gggagtatcg tgcgggatgt atggggttag gcgggggtat 173220 atagcgagcg gttttagaag ttttggtcgt tcggagtggg ggggtgttta gagtaagaga 173280 cgggttagga agttggagtg agtaaggagg ttttagtttt tggtgggagt aggtcgggta 173340 aaaataaatt aatttgaggg tagtagttag cgagattatt ataggagggg tggtggggtc 173400 ggaggggttt taggagttta ggagagggag gtattgttag aggtaaggtc ggtagatgag 173460 agttagtgtt ggtaggatta atttgttata gtagttatgg tttatttttt tttttttttt 173520 ttatatatgt ttttggggtt tatggaattt attagtttat tataaaggat attataaagg 173580 atatagggga agagatgtgt agggtaaggt atgggggagg gacgtagagt ttttatgtgt 173640 tttttaggcg ttttattttt taggagtttt tatatgttta tttatttaga agttttcgga 173700 attttatttt tttgagtgtt tacggaggtt ttattacgaa ggtatgattg atttaattat 173760 tggtcgttga tgatttgttt aatttttagt tttttttttt tatttggagg ttgcggggtg 173820 gtgttgaatt ttgtgatttt atttggtttt ttttgggaat tattttgaag ttgttagttg 173880 gtttgttaat tatgagtatt taaaaagata ttattttgga gattttaagg attttaggag 173940 ttgtgtgtta ggaaatggag atgaaaatta agtgtatatt ttataatatg atagttagtt 174000 ttttttaatt ttagttttat tttttgtcgt gttgtcggtt ttagtttttc gcgttttagg 174060 gtttttgaat atattgtcgg ttgtttgtag cgatcgtttt tgtttgttgg gtttgagttt 174120 ggtttatttt ttttattttt ttgcgtttag ttcgaaggtg ttttttcgag gtagtttttt 174180 tgatttggtt ttacgaatcg taggttttgt tttgttattg gttttttttg ttatatttgt 174240 tattttttgt gttttacgtt tattgatgtg gttttgtatt tgtgtagttt tatgagggta 174300 aggattgtgt ttggttttgt tttttacggg attttagcgt taagtttata gggagtattt 174360 aatgttgaat gaatgaatga gtgatcggta agggaggttt attttgttat gttgggggtt 174420 aaaggttgtt gggcggatta tatgggtgag gttgggtggg gagggaagta gagatgattt 174480 tttggaagaa ggggtaggag gcggggaggt gggtgtgggg tgttgtataa ggatggtaag 174540 tgtttttagg ggtgataagt taatttagag tattaggtag tagaaaaagg ttgatatttt 174600 tacgttttat ttttatttag ggagaggtta ggttttcggg aaagttagtt tttcgttgtt 174660 aggagagttt taagggaagt tttattagtt gttgagttgg ttatagtgga aatttatgtg 174720 gtgggtggga ggggtttgag gtataggggt ttgggtggtg gttttaggat ggagatttgt 174780 gtttagatta tgaggggtgg ttttagggat gattattttt aaataggaag tagataaagg 174840 tatagatggt agaagcggag gtagagaatg ggttgtaggg gtttttttag agggagagtc 174900 gagtaagggg ataggttgga aatatttagt ttttatggtt tgaagtatag atagttggtt 174960 ttatacgtag gtcgggtagt tatattattt agaataaggg gtatgttcgt agggtaggtt 175020 ttaggacgtt tcgggttggt tttgttatta gtttagaaag acggtttagg ttttttcggt 175080 agggagtacg tttagttagg ttttgggtag gagttgagat tttttggttg gtttgagagg 175140 ggatgatcga gtgtaggttt agttcgggat ttttttattt tttttcgtta tttagcggaa 175200 ttagttgggc gtgagaaaag aagagaagtg aattaagagt ttagagtatg aggttggatt 175260 agtttttata ttatatgtaa aaattaattt aatttgtatt aaagatttaa atttaagagt 175320 taaaattata aaatttttag aagaaaatat aggggaaaag ttttttgacg ttgtatttgg 175380 taatgatttt ttggatatgg cgttaaaagt ataggtaata gaagaataaa tagataaagt 175440 ggaacgttat agaagtttaa aatatttgta tattagtttg ggtgcggtga tttacgtttg 175500 taatttcggt attttgggag gtcgagacgg gtggattatt tgaggttagg agttcgagat 175560 taatttagtt aatatagtga aatttcgttt ttattaaaaa tataaaaatt agttgggtgt 175620 ggtggcgggt gtttgtaatt ttaattattt aggaggttga ggtaggaaaa tcgttggaat 175680 tagggaggcg gaggttgtag tgagttaaga ttatgttatt gtattttagt ttgggtaata 175740 gagttagatt ttattttaaa aaaaaaaaaa aaaattgtat attaaagggt attaataacg 175800 tggggagaag gtaatttatg gaatggtagt aaattatagg ttagatatgg gattagtatt 175860 tggatattaa tttatagatt ttttaatatt tagtaataat aattatttaa attaaatata 175920 ggtaaaggat ttggatagat atttttgtaa gaatatgtgt aaatgagtaa taaatacgaa 175980 aagatgttta atattattaa ttattgggga attgtaaatt aaaattataa ggagagattt 176040 tttataatta tgagttttgg gtaggtagga agacgtttgg tggggagttg tcggttttat 176100 gttgttttta gaatttttgt aggggttaag ttcgatttcg atattttatt aggagtatag 176160 aaacgagtgg aaaaggttaa aggttatttt aaagggttag aggggtttag taaggagttt 176220 gggatatgga attatgttgt gtatttagat atacggggat aataggggga tgaaaggtgg 176280 tttttaaaat ttatatttat tttagagttt atgaatatgg tttatttgga aaaagggttt 176340 ttgtagacgt tatgaagtta aggattttga gatgggatta ttttgggtta tttagtgggt 176400 tttaaattcg agaaagattg ttcgtatgag agatagatag ggggagattt agggtataga 176460 aggaggtttc gtgataacgg aggtagaggt cgagtggtgt ggttacgagt taaggaacgt 176520 taagggtttc gggagtcgtt agaagttgtt agaggcgaga agtaggtttt ttttcggagt 176580 tttcggaaag aattaggttt gttgatgtcg tgatttcgga tttttggttt ttagaacggc 176640 gagagaagaa atgtttggtg ttttgagtta tttagtttgt ggtatttggt gatggtagtt 176700 ttaggaaatt attataggga ttagagtttt tacggggttg ggtaggaagc gggtgtagag 176760 cgcgttaggt taggtttttt atttcggaga tggaaaagta gagttggaga ggttgagatc 176820 ggataggtat cgagcgttta ggggtaagaa tttttagggg atggtagagg ttatcgggga 176880 tagtatagcg agggatagga gggaggggtg agggttgagg tatcgttttt taggaggttt 176940 cggtttttcg tttattgatg atttaggaat ttcgtaagag gagttgggtt ttattttgtg 177000 tcgtattgta ttagatggat tttggtgggg atagacgttt agcgatagcg tggttaagtt 177060 ttttttagga tttcgggttt gtatttatga ttatgtatag acggttattt tttttgtttg 177120 tagttttttt tcgtggtttg tttttagttt tttagtttaa tagagttttt tagtggaaag 177180 tttttttttt ggagattttt tttttgttga aatataagtt tttggaataa gataaaattg 177240 tttaatttgt aaaagttata aagtcgtttt agaataaaaa aaaagtttcg atttttggtt 177300 ggaaggagtg gttttttatg ttttagcggt tagttattat tttatgattt atgtcggttt 177360 tgttgataaa ttttttagta tttttttagg ggaaggttat agtttttagg gagggcggga 177420 gagtatttag gttttcgttt ataaattaga tcggagttag atattgtcga gggagggata 177480 agagggtagg ttttggggtt tttaagtttt ttttggggtt ggtagattat cgtggattta 177540 ttagggtagg attatttttt tttataaatt ttttttgggt agttgtaggg tagtttgagt 177600 tggatacgtt ttatacgtta gtttagtggg gtatgaggta tttatagtta cgtttggaag 177660 ttagcgggtc ggtatttgtc gggtaggttt ttgttatata ggtatagcgt tttttttatg 177720 gttttttttt aggttagagt atgtttgggg attagagtag ttttcgtagt ggtttgtagt 177780 ttgataacgc ggcgtgagtt atgttttgta gagaagaaga gttttttagt gagggaagag 177840 gcgtttataa aatttaggat acgcgtagaa attcgtagga ggtgggggcg ttgtttaggg 177900 gtcgtgtcgt ttttattttt tattttgtag atgacggaat tgcggtttag agttgttaag 177960 tggtttgttt aaggttattt agtagggata ggaaggaagt tattttttta gggattgtgc 178020 gggagtttag tgataattaa agattagcgt taaagtttgt ttaggacgag aattttatta 178080 agggaaatag tttcgggatt gtcgtgttta ttcggaaggt agttagttta taattgagtt 178140 tttaaaaatg tacgtttttt tatatgaaaa tatattcgaa tgggattttg tagaaagtat 178200 tttttattaa ggtatagttc gaggggaggt tttcgtttta tttttggttg tgttgttttt 178260 agttaagggt agtagggatt agagtggttt ttggggtata gtattggttg tttttaaaga 178320 gtgttttgtt tagtttatga aaagttcgtg ttttgtgagt ttgggagggt gttattattt 178380 ttagtttttt agggagtatt atttttaaat ttacgttttt ttgtttagtt tttagatttt 178440 ttgttggtta tttatttggg tttcggttag attatttata aagtgaaggt cgaattcgag 178500 gtttttcgag gtttttgtta gttaggcggg tggagtgacg tttttttggg gttggtggtt 178560 taggaggtag gggatttatt gtggtttgtt taggttgttt ggtggggtgg ttatttcgag 178620 gacggtttta ttgtgtaagt ttgacgaagg ttttttttag cgttttttgt tttgcggttt 178680 ttgttgggcg gagagtagga cgttgggttt tatatttatt cgttttagcg ggtttgagtt 178740 ttcgagttta aatagataag atgtagtttt attgttattt aagttttttg tcgttttttt 178800 tggttttttt ttgaggttcg tttgttgtgt tcgattgggt gtgtttagcg gtataatata 178860 tattcgtttt attagtttta acgtgataat taagatgtgg ttttgaggtc gggcgtcgtg 178920 gtttacgttt gtaattttag tattttggga ggttgaggcg ggcggattac gagattagga 178980 gatcgagatt attttggttg atacggtgaa attttatttt tattaaaaat ataaaaaaat 179040 atggcgggcg tttatagttt tagttgtttg ggaggttgag gtaggagaat ggtatgaatt 179100 agggaggcgg agtttgtagt gagttgagat cgcgttattg tattttagtt tgggtaatag 179160 agttagattt cgttttaaag aaaaaaaaaa aaaaagatgt ggttttggga gtagtggtgg 179220 aggggattat acgttttaga gaggagttat cgagatgggt tttttttttt taggtttttt 179280 agggattttt taatatatat atagtggtaa ttaatagatt agggtttaag gtacgtaggg 179340 gttgatattt ttagcgattt ttcgttttat ggttcgtagg ttattttaga atatttaaag 179400 tttggagttt ggtttagtta ttttatgttt tttagcgttg ggtttagagg gcggtatgag 179460 cggtagaaat tgttattatt gttaattatc gatgacggcg ttggttacgt gagatggtag 179520 ttacggtatc gtatgtgagt gaagggatta aggaggttgg gtttgggagg gagggtttgg 179580 aaagttgggg tgaattaaag gtaggggagt tttttttttt tttatttgtt tgtttacgtt 179640 ttgatgggtt tgtgtttgcg gtaagggggt tgttagcgtg aatggatata cgtatatata 179700 tgtatatata cgtgtatata tacgttaggt ttttttgagc gtcgggagtt ttttttttta 179760 taattaattg ttaggaaggt atagaaatgt tattttaggt aggagatcga ggtagttttg 179820 aagatagatt ttggttggaa gtaaaaaata aattatatag tggataaatt aattattagt 179880 taggtttaag cgtcgtcgtt ttagattcga gttagggggg taggtttttt atattttttt 179940 aaggtttcgg cgttaatagt tttagtattg atagtggtta tgatatgtaa gaatggtata 180000 ttggaaaatg aaagggaagt agttaggaga gaggagagtc gagtttaaat aaaagttaga 180060 tttaggagag tttagttttt gagacggagt ttattttacg agtttggaat cgttaaaaag 180120 aaaagaaata tttttgtgaa aaatgagtaa aagcgttttt tgtatgttta tttttttagg 180180 tataaataaa gtttcgagtt tagggtagtg gggggcggtc gatggggagg gggttgtttg 180240 cgtatttgag attcggtttt tttttatttt tacggatata tttagtagcg gcgggagttt 180300 cggcgtttcg tttagaggcg gttttttttt ttttattttc gtcgtttttt tttttttagt 180360 tttttttttt tttttttttt tttttaaaaa tattttttgt ttggtttaat ttttttaatt 180420 tgttgtaatt acgaatgtat tcgaattatt atatttttat gtgttgatta tatgtttgtg 180480 ttttaaattg aagtagtatt gtttttttaa aacgggagga aaaagggagt aaaggagaga 180540 aatttaaaaa taggaggtag gagagagggt tcgaagtggg tttcgaggag ttcggtagat 180600 tatcgggttt gtttgcgaga gttttagagt ttcggtcgtt cggtttggtc ggtggttgta 180660 gaggtttcga gtgcggtttt cggtagtttt ttttttttat tttttttagt tttcgtcgtt 180720 tcgaggtttg ttgttttttt ttaatattta tttggagatg tttaatttag atttttggaa 180780 attaatttat agagttaaat ttttgacgat ttttaaagtt ttttattttt tttgtttcgc 180840 gatgttacga tttttttggg tttaagggtt taaaaagttt agtttttgcg tgtttgtttc 180900 gttttttttt gttttgggtt ggttttagtt tttttttatt ttgtatttta acgtggttgg 180960 gtaggaggaa cggtcgtgtt ttaggttagc gtgttgagaa aaggtttcgg agtatttgtt 181020 taggaggaat tttgagaagt tatttttttt cgttttatta gtttgtagtg atagaggtag 181080 ttgtcgtttt cgtttaggta gagagggcga acgggacggg gattttttgg aagattttta 181140 ttatatacgt atgagttagt gagtttttag tcgttttttg ggagggagcg agtttttttt 181200 ttcgggaatt cggggtttta ttgggggatt agtgttgttt tttattgttt attcggggtt 181260 tttagaggtt gtttatttat ttggggggtt tttattagta tatggttagg gtttatgttg 181320 aggttaaggg tttagtagag taggtggggg tttataatgt gggtttttgg ggtgggaatt 181380 aggggtattt tttttgtttt taagttttat tttaagggtt tatttaaatt cgagatacgg 181440 aggttggttt tgttggttta agtttgttta aagagaatgt gtgtttgtgt taaggttgag 181500 aatttaggta atttttttga aaattttaga ttgttagttt ttgttgagaa agggaggacg 181560 cgtggtcgta ttacggaagt ttttttgttt ggtcgtatag ggttggtata agatagtttt 181620 gttttttaga taaaatattt tttagtttgt gttgtttttt aaggttttta ataaatttat 181680 aatatttgta tttttttatt tcgatatatt tcgtaggttt ttgagtttat aatttttgtt 181740 ttatagagtt aggtgagtta tttgtgatta ggtgaggttt atgtatagtt ttcggttaga 181800 tgatagagtt aaaggttttg aagtgttatt ttaggttata gtttcgttcg ttttttgttt 181860 gggataggat tttaaatgta atttttttgg tagaaaggat atttttttgg ggggtgggga 181920 ggattatttt tagttttttg ggagatatta agtaattatt tttttttaaa gagtttggag 181980 gatagtttta taggtagtta gatagtgagg gaggtgggga tagtatttta gtcgaggtgg 182040 gaggttgggg aggaagggag ggattatagt tacgagagaa ggttgaataa tggttttagg 182100 gatagtatgt tttaattttt agatttgtaa atgggatttt gtttggaata agagtttttg 182160 tatttgtgat ttagttgtag attttgttgt ggcgagagta ttttggatgg tttaggtggt 182220 ttttaaaggt agtttcggtg tttatataag acgggggtag agggagattt gatatagata 182280 gggatggtta agtggagatg gggttcggag agatttgtag atgttggtgt tgaaggtaag 182340 ggttatgtag ttataagtta agggatattt atagttatta gaggtttaaa ggggtaggcg 182400 atgaaggtag tggtttttaa tttttttggt atttgggatc ggttttaggg aagataattt 182460 ttttatagat tagggagtgg ggagatggtt ttgagatgat ttaagtgtat tatatttatt 182520 attttatttt attttatttt attgagatag agtttcgttt tgttatttag gttggagtat 182580 agtggtatta ttttagttta ttgtaatttt cgttatttgg gtttaagtaa tttttttgtt 182640 ttagtttttt aagaagttgg gattatagac gtttgttatc gtgttcggtt aatttttgta 182700 tttttagtag aaacggggtt ttattatatt ggttaggttg attttgaatt tttgatttcg 182760 tgattcgtta gttttggttt tttaaagtgt tgggattata ggtataagtt attgtgtttg 182820 gtttttattt tttatttttt gagatagagt tttattttgg gattataggt gtgagttatt 182880 gtattcggtt ataagtacgt tgtattgatt gtgtatttta tttttattat tattataata 182940 tataatgaga taattatata atttattata atgtagaatt agttggagtt ttgagtttat 183000 ttttttgtaa ttagacggtt ttatttggtg gtgatgggag acggtgatag attattaggt 183060 attagatttt tataagaagt acgtaattta gattttttat atgtgtcgtt tataatacgg 183120 tttatttttt tataagaatt taatgttatg gttgattaga taggaggtag agtttgggta 183180 gtaatgcgag taatggggag tgattgtaaa tatagatgaa gtttcgttcg tttgttagtt 183240 atttattttt tgttgtgtag gttagttttt aataggatat acggggttgg gaatttttgt 183300 tttagagttt ttagagggtt atgtttagtg gatattttga ttttagtttg gtgattttga 183360 tttcggatgt gtggtttgta gagttgtgag aggatggttg ggcgttgttg tgatttagtt 183420 agtttgtggt tattcgttat agtagttgta ggaaattgat gtagcgttat agacggagtt 183480 agggtttagt ttattggagt tgttttttgt tattttattt ttttttaaaa tattgtgtta 183540 agttaattat taataattat tgatttcgat gggtaggaat cgtagaggtt ttttggtttg 183600 tttttttaat ttttttttta attttgaaat aatatttttt gttggttttt ttgattataa 183660 atgtaatatt tttttttgta ttgagtttag aaataagaga aaaagtaaaa agtagaaatt 183720 ttagttgggt aaggtggtac gtgtttgtaa ttttagtatt ttgggaggtt gcggcggaag 183780 gattgtttga agttaggagt tcgaggttgt tgtgagttat aattgtatta ttgtattttg 183840 gttgggtaaa aagagtgaga ttttgtttta aattaaaaaa aaaaaaaaag aagaggaaga 183900 aaatttatta attttattcg agatttttta tacgaatttt tgttgtgggg tagggaagtt 183960 taggaaggtt ttacgaggtt ttgatttagt ttggttggcg gtgggaattt gggaatagtt 184020 tcgagtgagg ggtcgggtta tgattgagtt tatttattta gttatttttt gtacgttgtg 184080 tatattatgg gtttgacggt tagggttgga gtatttgttg agtatagttt tgatttttag 184140 ttttatttag tatggtttgg tttgaggttt attttttttt cgtgtttgaa aatttaaata 184200 ttttggttta ggcgggggat tatttgaaat ggaaaatttg gtagtatcga ttggttttga 184260 agaggtagga gttagttatg agtcggttgg gaggcgagtg tagaggtggt gaggtaaggt 184320 tagtagaggg tgggggaggc gagggttaat tttttatcgc gtatggtgta agtattaagg 184380 gggtatttta ttaggttagt gtagatttag gtttttgcgg tggatttttc gcggtttttt 184440 tttttagagg aatattgaag aggtttttgt ggttttgttt tagatttaga ggtatatttg 184500 tatattaaac gtattgagta attttatagt gagggagtcg ggtttggttt aatttatttt 184560 tttttaaatt ggattaaagg ttgttgtttt aggaaggtag ggtttttagg tttacggttt 184620 tgggaaattt tggttgtgtt agtttatgag tttagttttt agttatttta gtttgtttat 184680 attttggagt gggtattgtt atttaaaagt tttttttaga tagtttttag ggcggtattt 184740 ttgtttttta ttttttatag atttttggtt atttttttgc gatattagta ttattggttt 184800 atagtttttt ttaattgtaa agtggggttt agcggtatag gttgggtttg gtagggcggg 184860 aaggaagagc gaaggttatt ttgtttttaa tagtattggt cgggttttgg aaaggtcgga 184920 atttatagat aggaaggaag tgttatattt atttaatttg ttttgcgtta gttagggggt 184980 attttgtaga aagaagttag gtggtcgtgg tcgggtgtag tggtttatgt ttgtaatttt 185040 agtattttgg gaggtcgagg taggtggatt ataaggttag gggttttaga ttagtttgat 185100 taatatggtg aaatttcgtt tttattaaaa atataaaaat tagttgggta tggtggcgta 185160 tgtttgtaat tttagttatt tagaaggttg aggtaggaga attgtttgaa tttgggaggt 185220 ggaggttgta gtgagtttag attacgttat tgtattttag tttgggcgat agcgcgagat 185280 tttattttaa aaaaaaaaaa aagaagttag gtggttattt tttagttttt ggtttggttt 185340 aggaattgtt ttttttttaa gatgttatta aatgtttttt ttattaggaa gttttttttg 185400 gttgtttttt ttatttttgt ttttgtttta gaatacggtt cggtttttac ggataatttt 185460 gatattagag tttaatagag attttttttt ttatggaaat ttatatttta aattgaatat 185520 gtgtgtagga taagtttttg tttttatgtg aaataaaagt gaaaggtgcg gattatttgt 185580 ttttttttat ttttttttat aataatttgg gttttatagg ggtttagtag gagttaggtt 185640 tagtttagtc gttttaggtg tattattttg ggtattagcg tttttgtttt tttttacgaa 185700 gtatagtttt attttttggt atttagtggg gaggggatat atattaggta ttttttaggg 185760 tggattgtgt tttttatatt aggttaggag gttttggggt tggtttagtt atttagaaaa 185820 gggagtaggc ggtttaggtg atattgatgt gggtagtagg ggttttcggg aaagggtttt 185880 cgtaggatcg gttttatttt gttttaggag tatatattgg ggaagggtgt tgcgcggagg 185940 tggagagaac gtatttttgg ttgaaagtat gttttttgat gttttgggtt cggatttgtt 186000 gttatttttt atgttttttt atttaatata cgttttagta aattttttat gttgatgagc 186060 gttaagttat agaggacgta taatttttcg ttttaaaaag tgattttttt tgttgggtgt 186120 ggtggtttat atttgtaatt ttaatatttt gggaggttaa agtgggagga ttatttgagg 186180 ttaagagttt aagattagtt tgggtaatat agagaaattt tatttttata aaaaaaaaaa 186240 aaaaaaaaaa aagtttaggt atagtggttt atgtttgtaa ttttagttat ttgggaggtt 186300 gaggtaggag aattatttga atttgggagg tagagattgt agtgagttaa gattatgtta 186360 ttgtatttta gtttgggtaa tagagtaaga ttttatttta aaaaaaaaaa aaattttttt 186420 ttttgaaata gggttttatt ttttttgttt aggttggagg atagtgacgt gattataatt 186480 tattgtagtt ttagtttttc gggtagttgg aattataggg ttgtattatt acgtttagtt 186540 aattttttgt atttttagtt aagacggggt ttcgttatgt tgtttaggtt ggtttggagt 186600 atttgagttt aagtgatttt tttatttcgg ttttaaaagt attgggatta taggtatggg 186660 ttattatgtt tagtttgaaa atattttttt taagaattag ttagttatgg tggcgtataa 186720 ttgtagtttt agttatttag gaggttaagg taggaggatt ttttgagttt ggtaggttga 186780 ggttgtagtg agttataatt gtgttattgt attttagttt gggggataga gaaagatttt 186840 gtttagaaag aaaaaagaaa aaaaaaagat ttttttattt attttttgtt tatttttaga 186900 tttaattatt gaagtttgtt tttttgaatt aaaaatgaag gagtttcgtt ttggattttt 186960 ttttgttgat tttgttattg tatttgttag tagagttagt taagattttt taggttggtt 187020 ttagtttggt tcgtttatag ttttttaagt aagacggatt tttaggttga ggttagttgt 187080 attttttttt ggaatttttt tttatttttt attgtgtttt agattttggt tgtttttaaa 187140 taaatataat ttagttattt ttgtttttgg ggtcgttgta gggtttattg gtgtaaatcg 187200 tttgggtagg tttgttgttt taggagtttt tttaggttag cgtggaagga aattaagata 187260 acggggagaa gtagttcggt tgggtttaat tttattttta tatgttcgtg tttagttaat 187320 tatttgggtt gtagtttgat aggagttgga gttggcgttt tatttttaga gggggttttc 187380 gattgttttt gtagagcgag ggaggtttgg gggtgtagag gttaagggtt tttgtagagt 187440 ttgttttagg ttttttgagt ttaagttttt ttgtagttaa cggaagattt tttcgagagc 187500 gggtgttttt tattttgttt gtttagtagg tgtttagtaa tcgtttattg gataaataat 187560 gaatttgtgg atttaacgtg aagatgattt aaattagcgt ttttttatag aatttttcgt 187620 aatgatgtta atgttttgta tttgtcgtag ttaatatggt agttatatgt ggtagtgaac 187680 gtttgtaatg tggaagggtt attaaggtaa agagtttcgt atttatgtta taatttaaat 187740 ttaaatagtt ataaatgttt agcgtgtgtt tcgttatata gatttttttt gttatttttt 187800 tttttttttt agagatattg tattcgttat taatttttta ttcgggaggt aaacggagaa 187860 atgttatttt ttagttaacg taaaagaagg ttaatatttg tattttaagt tagttttttg 187920 ggtaattttt ttaagtattt tttattaagg ttagtttagt aatatttttt gattgtttgt 187980 tacgtattag gaaagtattt cgtcgtggtt ttggttcgag gttatggagg atatagaaat 188040 aattaaggtt aagttgatag aaggggtgtg ataagatggt ttaaagttat tgagttagtt 188100 aggaggttta ggagtatgga agttttgttt tttagaggat aagtggtaat ttatttaggg 188160 ggggttcgag tatttagagt taggagcgta gaagtagggg gttttaggtt ggaaagcggt 188220 attagggtta ggttgggcgg tagtacgaat ttattttcga ggttttgggg gcggaaatta 188280 agggttttat gagtaagaag attcggttta ggtttaatgg aaatgatcgg gtggagggat 188340 tttattattc ggtttttagt atatagggag ggaagtggta atcgtttttt aaatgttggt 188400 cgtggagggg aaggagttat agtagggtag gggtggggag gatggtattt gttggtttaa 188460 ggagggatga tggaggttta attaagatat gatcgtgatc ggggtagttt gtttaagggt 188520 tagtatgtag agggcgagtt gatgagattt tggtagtttg ttgagatttg ggggtgttgg 188580 ggaggtagag gttaaggtta attttgagat tttttgtttg taaatttggg tgggtggtaa 188640 ggttgatatt agagaaatag aggaagagtg ggtagttatg ggtgagagag gaagtaatga 188700 attaggggtg tttgtaagag tttaggggta aggttttcgg gtagttaaga tgttggtggt 188760 tttttttacg attagttttt tttacgtggt atatttttgt ttgtatggtt gggtatgggg 188820 tatttgttcg ttcgatatat tttgagtagt tattttgtgt attgaggtaa cgtggtacgg 188880 tgttttgggg aaatagcgag gaggtattgt ataggtttta tttttttggt attttttgtt 188940 ttttggggat ggtggtagtt aaataagtga tagttaattg ttaggagagt ttggttttga 189000 tttattaggt ggagttaggt atttttgtcg gaagaggtat gggaattagt ataggatgaa 189060 gggaggtagc gagtattagt ttaggttttg tttttatagg gttttttttt tatatttatt 189120 tgtgtaggcg ttttttgtga gggtagagat atttgtagtg tttgagggag attttttgcg 189180 ggcggggtcg tttatttata gcggttaggt gggaggtgta ttagtgtttt gtggttgtta 189240 taatggatta tagttgtggg gtttgaaaaa atggaagcgg gttttttttt atgttggagg 189300 ttagaggttt aaaattaagg tgttagtaag gttatatttt ttagggaggt tttggggtgg 189360 ggtggggggg gggttttttt ttgttttttt ttagacgttt tttggtttgg ggttgcgtta 189420 ttttattatt tgtttttgtt tttacgtggt ttttttcggt gtgtttgtgg tttttttgtt 189480 ttttttaagg atattagttg ttggatttag ggtttatttt aatttagaat gattttattt 189540 taagattttt aattatttat atttgtaaag attttatttt taatttttag gttatatttt 189600 gaggtttttg gtggatatga gtttgtgggg gatacggttt aatttaggat agaagggatg 189660 atgggggtat tggggaaaag gttatatatt ttagaggtat tggaagatgg aagagtagga 189720 tttagcgata cgggatgtta ggtagaggag ttggttttaa ggattttagt cggggtttga 189780 gggttagagg gagggaagtt taggtattat tgagatgaaa tgtttcgtgt atcgtgggaa 189840 atagggtaaa agttcgttgg acgtttagtt agagaggcgg ttgtttgagg tatagaaaat 189900 gagcgaatat gggagagttt attagaaggt tattcgggag ggcgtggtgg taatatttag 189960 aagggttgag aagcgtattt ttatagttta gttaaattta tttggggaaa tatacgtttt 190020 cggtagtatt agtaatagag aagattttcg gcgatgttat tagtgggtta cgggacgggt 190080 aaattttgtt tttttatata gaggaatatt cgttagttgt taaaataagt gaattaaggt 190140 ttcgtggatt tatacggata agtttttacg tcgttacgtt gtgggtatag gtagggtagt 190200 tattgatttt agtgaggtat taaggatgtg atgttgatga cggtatttaa gaggagatag 190260 atttaggttg tttagttata cgatgttgat gatcgtatgt aagaggagat taggtcggat 190320 gcggtggttt atatttataa ttttagtatt ttgggaggtt aaggtaggtg gattatttga 190380 ggttaggggt atgagattag tttgattaat atggtgaaat tttgtgttta ttaaaaatat 190440 aaaaaaaatt agttagatat ggtggcgggt gtttgtaatt ttggttattg aggaggttga 190500 ggtagaagaa tcgtttgaat ttaggaggta gaggttgtag tgagtcgaga tggtgttatt 190560 gtattttagt ttgggcgata gagcgagatt ttattttaaa aaaaaaaaaa aggagattta 190620 ggttttttag atatattatt gtttagtata gatgtgtttg ttcggggtta gattttaatt 190680 tagaggggcg ggtatcgtag taggagtggg gttaggatgg agaaggttat ttagggttgc 190740 ggttatattt gtaatgtttt attttttaag cgggatggtg agtatatagg tgttttatta 190800 ttttattttt tatatttttg ttttgtagtt ttaagaattt tatttttttt ttaaaaggaa 190860 agaaagtgtg tgagttgatt aaagcgttga ttatggtgtt atttaagttt ttgttagaaa 190920 tgttattttt ggtttagttt taaatataat ttcgagaaga gttttcgttt ttttggggag 190980 ggtaagagtt ttagatatag gagattggtt agatgtggat ttatagagaa gttgggttgg 191040 gaggatggga tggtagatag tcgtttgggg agtgttaaat ggggaggtcg gagatgttgg 191100 ggcgtttagg aatgaatttt tgtttggatt agggttttag taaaagggag gtagggagaa 191160 agaaagaagt taagaagatg aggaaagggt gtttcgggtt agagtttata gaggtttata 191220 gagggaggat ttcgtgtgtt agtaggtagt tttacgtaaa tttagattat tagtttgtag 191280 ttttgggatt tagtaaatta tgttttaggt ttttaagttg agttgtgatc gtggttgtta 191340 agtgttgata gtatagaatt agttagtttg agtagaggga agtaatcgtc gggggaggtt 191400 gtgtttatgt agtttagggt gttaggtttt taagatgtaa tttttataag aattggggga 191460 ttttttttat ttattttatt agaagttggt taatgagagg gaaggagatg gagaggtaga 191520 ttagatgcgg agtcggagaa aagtttttta gaaatatagt agcggttggg ttgtttagtg 191580 gttagtgttt aatatgattg cgatgggcgg agtttttttt aattatagcg ttgaattatg 191640 tagttgttta ggggttttta gttagagtat tatttttttt tttttatata tagttttatt 191700 ttgtattgta aggggtttta tatgtattta atgtggatac ggtatttttt ttatttttat 191760 tttttgtaaa aagttatttt ttttattgtt taggtttggt ggtgtatagt ttacgggtat 191820 tgtatttatt tttggaaggt agatttagga ggcgtttgtg ttgtttttat agaagtaagt 191880 ttaggattag aagtaggttt tgggtttaga attttgaggt tttaggtgtt agtgtggttt 191940 ggaattgttt agttttatag ttattagtta tacgtagata taagtggaaa tttatttaaa 192000 ataaataaat aattttatgt aagtaaatga gtgaataaag taaacgtaaa tatttatatt 192060 ttgagtgtgt aatagattta ggcggttaag cggttattat ataggatggc ggagtgtaga 192120 tgtatagaat agatttatta ttatagaagg ttttattaga cggagttggt ttagagtatg 192180 gaggtggcgg ttttagatgg gtatatgttt ttgttttcgt aggcgttttg ttttggtagg 192240 acggttgttt tattttgttt tgaaggtagt tttggtttat aggcgtttta tttgtgtgga 192300 tttgatttcg ggttcgtgtt ttttggtaat tttgtttttt ttagaatggt taatttatga 192360 aggtatagtt tttgtttgtt tgttattatg atggtagtta ggggtttggt atttagttgg 192420 tttttagtat atatgtatag gtgattacgt tatttttgtt ttttttagag tttttcgttt 192480 tttaggggag gtaagtttat ttattgttgt gatttattat tttttttaaa tagaaaagtt 192540 attagatggg tatttgtttt agtttggtcg ttggaagtga tagttaagaa taacgtaggt 192600 ttttagaaat agaggtatta gtatggttat attggggtta ggtaggggag attagggata 192660 tttagtgggg agaagatgac gcgtagattt agttttgggg ggtaagggtt ggaggtagag 192720 ttttgatttt tttgttttat ttttttgttt aggttgtatt tagtgttggt agagtttttt 192780 taagtttata agttgtaatt cgtgttttgg acggttagtt ttagagtttt gatgggtgta 192840 tttgtttttt ttttttattg gttagtgtgg aaaattttta aatatatgga aaaagtataa 192900 ggagtagtat agtgattatt gttagaggtt tatttatttt tttttagata atatcggacg 192960 tatttgtttt attttggagt attttttatt ttgtaaggtt gtagggagtt tatagatatt 193020 gaattaatat cgagaggttt acggttaaag ttatttgttt atggtatatt tgttttttta 193080 gtattttaaa ttaaattatt tagttttatt tattttttgt tttttttttt gtttcgtata 193140 tacgggtttg ttttttgagt ttgggggtgg ttgtttttgt ttttataagg attattttta 193200 gtagggtagc gtcgataggt ttggaagtta tttgagttta aagtcgttaa agattgcgtt 193260 tttttgggaa atgggtaagt ggttttattt atttagggaa gttaggtggg gaggtaggtt 193320 ttagattaga atgaagggat tttagtataa atatatttat gagttgggtg gggttagagc 193380 ggagcgagtt atttatttgg gttattggag ttattaagtt ttcggagtcg gttattggag 193440 gttcgcgtgt tttttaaaga tagagataaa gggtaaaggt tatataaggt tattggcgtt 193500 tttttttcgg gtggatgatt aatattagga atgttttcgt ttttgttttt gttgtgagtt 193560 ttagagttag aaacggggtt tatttgggga tagaggtttt atttttttag gtaattttgg 193620 acgttggagg gatgatagtt attgttgttt ggttgttgga ggggttttgg gttaaatttt 193680 tatatatatt tttttttaag ttttattatt tttgttttgt agataaggaa tttgagtttt 193740 tatagagtgt tatttttttg tggttatata gtgaatgaga gttgtatata ggtgagttta 193800 cgtttattag attttaagtt gggttgtatt taagcgtgtt tttgttggac ggagtttttt 193860 ttttttttta tgtttattcg ttttatgaat tagggttttt ttatattagg gtttataatt 193920 tacgggtagt tttgatttag ttttttttat ttttagggtt gggtgtagtc gggttggatt 193980 tggggatgga gtgggatagg ttatttttat tttttgtttt aggagggaat aaaaatagaa 194040 ttttagatta atgtagtttt tcgcggtatg cgtttttttt gtttatatat aggttttggt 194100 ttggggttgt ttgttggaga ggtttatggt aggtaagttt taattcgagg agatttgttg 194160 aggtgttaag ttaagtaaat tcgaaaggtt gttaggagga gcggttttgg gagtataggc 194220 ggttatttta ttgttgtaga gtacggtatt ttggggatgt tttttgggta atgttatata 194280 gttatttttt agagagtttt agggatatat aattagttta gttttattaa tagtgagata 194340 agggattagg tagatttaga tatttttttg tatttgatta ttatgttggt tgttggttaa 194400 agatgttagt ttttttttgg aattttttag aaaggttttt gtagtattta tttatttatt 194460 tatttattta tttattttat ttatttattt atttatttat ttatttatgg attttattta 194520 ttttattatt tttttatata tttatttatt tatttattta atttatttat ttagtttttt 194580 atttatttat ttatttatta atttatttat ttgtttattt aatttattta tttattaatt 194640 tatttattta ttatttattt atttatttat ttatttattt atttttttat ttatttattt 194700 attttttttt ttatttattt tataatttta tttttaaatt gtgattagat ggaaatgggt 194760 gtagttagtt tgtttttaaa ggtttagagc ggaggtagag tgaattgttt atttggtttt 194820 cgtgtttagt agtttaggtt tgtatatatg ttttataatt ataggatatt agatttagta 194880 attggtagta gaatgagtat agtgtatttt tcgcggaatt agtattgata gggtatttat 194940 ttttattaag tttgagtttt tttggtgttg gagggaattt ttagatgggt tttaatttta 195000 gttgaattta ttttttaggg aaagtaatat cgtgagaaat gcgtgtgata taaggtttta 195060 aagagggtgt gggtcgtgat ttttggagta attagggagg ttttatggag gagatgagga 195120 taaagttgag ttttgaagga gggatcggag gacgttgagt agggatattt atttttgttt 195180 gcgagggttt gacggtaggt tgtgagttgt attttagttt cgatttattt aatttataat 195240 tttagtaggt aggtgttttc gttttatttt atagaggagg aagcgaggtt tagggttggg 195300 taaattgttt aaggtcgtat agttgcggaa tttattttta gtatttttag tttgttttag 195360 ttatgttcgt gattttattt agtatttttt ttttggtgtt tatttatttt gtttattgtt 195420 aagtaataaa aattttatta ggaaaattta ggggtttttg gttagttttt ttagatagaa 195480 aggtagattt cggcgtagat ttttaggaag taaggatgga agggttagta tttgtttttt 195540 agaaatgata gtttttttaa gattaggaga gatggtttag agtgtagttt cggtgggttg 195600 tttaggatta ggaggggaga ggagcgggga ggaggatgaa ttttattttt aaggttgttg 195660 agtggtatat agtgagtttg gattttttag ttttagttga gtttattttt acgatggtta 195720 tgagtatttt ttttatatat tcgattggaa gtcgtattgt atataacgta tacggggtta 195780 ttattttttg ttttatatat ttttacgtat atattattag tgtattattg ggatattttg 195840 ttgttcgggg ttgagagtga attagaattt tgtttataaa tttagtatat tttattgtgg 195900 aaataatggg gggtaaggag gggtcgttta gtaaagaata ggatatacgt ttttgaggat 195960 ggagttattt ttggttgaga tatttttgta ggggatgtcg gcgataaagg ttgttttatt 196020 tttttttttg ggttagatgg atattatttt tgttttttgt tttttagtat taggtaaaag 196080 gaaaatagaa gaggttttat ttaggttaaa tattttaggg ttttttattc gtaggaaata 196140 tgttggttta ttttttttaa atttagtatg ggggtggaga aacggtgggg aaaatagtat 196200 ttgttttaga ttttttgggt ggagtttttg ttttatttat attgtttatt tttttgattt 196260 tttaaaatgg gtatttggtg tttggtagtt tttggtatag agaagacgta aagtaaatcg 196320 tttataagaa gggggcgagc gtagtttgag tattttttgt ttttgaataa attgttaggt 196380 ttagcgtagt cgttgtcgtt attgttgttt ttaggaaggg atttttggtt acgagcggtt 196440 ttagtttagt tttttggatt taattattta ggtttgtgtt tgagtttagt aaagaggtag 196500 ttagaaaagt ttttaagata tttaacgatt tcgtggtttt agttgagaag tgagttattt 196560 ttatgtgatt ttaaaataaa atatatttag aaggagagaa gataattgaa atttagttgt 196620 ttggagttat tttagatgaa agtatttgag tttttgggag gtaaaggagg taggaaagtt 196680 tggagttaga tgattagaat ttgaacgtag atttcgttag gtttttgttg tgggttttgg 196740 gagatgattt ttattttttg agttttagtt tttttgggga tagagatggt gtttatttat 196800 aggttgtttc gagttaatga ggttatatgg cgtaagtatt agtatagtgt ttggtataaa 196860 attaaaattt aataagtgat attattatta ttattattat tattattatt tttgagatgg 196920 agttttgttt tgttatttag gttggattgt agtggtacga ttttagttta tcgtaatttt 196980 cgttttttaa gtagttgaga ttataggtat ttgttattac gtttcggtta atttttgtat 197040 attcggtaga gatagggttt tattacgttg gttaggttgg tttcgaattg attttaggtg 197100 atttgtttgt tttagttttt taaagtgttc ggattatagg cgttagttat cgttatttgg 197160 ttgtgatatt attataatat taatattata atagttggtt aggtatggtg atttacgttt 197220 gtaattttag taatttggga ggttgacgtg ggttagttat tcgaggttag ttcgagatta 197280 gtttgattaa tatagggaaa ttttattttt attaaaaata taaaaattag tcgggcgtgg 197340 tggtattcgt ttgtaatttt agttattcgg gaggttaagg taggagaatc gtttgaattt 197400 aggagacgga ggttgtagtg agtcgagatt atattattgt attttagttt gggcgataga 197460 gtaagatttt gttttaaaaa ataataataa taaataaata aaatatattt tgacgagata 197520 tggtaaaaga tagtagaagg taggagttcg gggatttatt atgggtcggc gttttaagta 197580 gaaagaaatg tagtgtttat aagttagaga gtagatgtcg aagataggag acgagcgggg 197640 ttttttggtt ttggagagga aagggtgagt ttaggtagaa agagtaaatt tagggcgttt 197700 tgtgtagtgt tttttttgtg gaattagttt agggtattag tagtatagtt tttttttagt 197760 agtggagatt aggttaattg tttagtgttt tttttgtttt tttgttttaa ttttattaag 197820 tatagttttt ttttgggtat agtagttttg taggggtgga tattgattta tgtatttagg 197880 agtttagagg tttttttttt tttatttatt tatttagaga tggagttttt ttttgtcgtt 197940 taggttggag tgtagtggta ttaatttggt ttattgtaat ttttattttt taggtttaag 198000 tgattttttt gttttaattt tttgcgtagt tgggattata agtatgtatt attacgttcg 198060 gttaattttt gtatttttag tagagatggg gttttattat gttggttagg ttggtttcga 198120 atttttgatt ttgtgatttt tttattttgg ttttttaaag tgttgggatt atagacgtga 198180 gttattacgt tcggttaggg gtttttttta atggattttt tttaatgtat ataatttggg 198240 gaatttagat ataagaaaga tatagagtat gaaggttttt tattggtttg tttattttta 198300 gaggtggggt tttaggtggt ttaggttggt tttaaatttt tggttttaag taattttttt 198360 gttttggttt tacgttggga ttataggtat aagttattac gtttagttat tttttttttt 198420 atttgggttg ttatgttaga atttggtaag ttataagatg gaaatgttta aataggtatt 198480 tagaatttga gtagatatta tttgatgtat tattgttgtt attttaatga ttgaaatgta 198540 tttattatat tcgttttttt aaaggttatt ttagattttt atagatttta tttgtgatgt 198600 aagatagtta ttttaaattt ttttgtgggt tcgaatagat tagatttttg aatttttggg 198660 tagagtaggg atggggttgt tttagaggag ggtgatatcg ttatattttt gttttgtttt 198720 tgtgttgata atgaatgagg tttggatagt ttttttttta ttaaaagtta tattttttta 198780 aaaaggagtt ttttaggatg aggcgttatg ataatttaat tgtgtataaa tatttatttt 198840 taataatgat agaagttatt tatagaaaag aatttatttt tggtcgggta cggtggttta 198900 ggtttgtaat tttagtattt tgagaggtta aggtaggtaa attatttgag gttcggagtt 198960 cgagattagt ttgattaata tggtgaaatt tcgtttttaa tgaaaatata aaattagttt 199020 gtatgtttgt aattttagtt atttaggaag ttgaggtaga agaagtattt gagttcgaga 199080 ggcggaggtt gtagtgagtc gagatcgtgt tattgtattt tagtttgggt gatagagcga 199140 aatttttttt taaaatatat atatatatat atatatatat atatatatat atatatataa 199200 atttattttt attttttttt ttgaaatttt tgagagaggt taggtgtagt ggtttatatt 199260 tgtaatttta gtagtttggg aggttgaggt gggaggatgg tttgaggtta ggagttggag 199320 attagtttgg gtaatatagt aagattttat ttttattaaa aaataataaa agtttaaaaa 199380 gtttttgaga tagtttttgg ggaaaggtgg gttatggaga tttttatttt ggttattcgt 199440 gtttttttcg tttgtttttt tgtggttttt ttttattttg agtttggggt gggggcggtt 199500 tgagtttagg atgggggtgg tttgagtttg gggtgggagc ggtttgagtt tgggataggg 199560 cggtttgagt tggggtgggg gcgttttaag tttgggttgc gggtattttg agtttggggt 199620 ggggatgttt tgagtttggg gtgggggtgt tttgagtttg ggttgagggt ggtttgagtt 199680 tgtgttgggg gtggtttgag ttgggatggg ggcggtttga gttgggatgg gggcggtttg 199740 agtttggggt gggggcgttt tgagtttggg atgggggtat tttgagtttg ggatgggggc 199800 gttttgagtt gggatggggg cgttttgagt ttgggatggg ggcggtttga gttgggatgg 199860 gggcggtttg agtttggggt gggggcggtt tgagtttggg gtgggggcgt ttaggatgta 199920 taggttttat tttttttttt tgaggtttag tttgtttata ggagttgtga agggttggat 199980 taaagttaaa ggtttaaatt ttagatttat ttttagattt agtggataat taaaatattt 200040 aagtttattt ttaaaggaag ttgagataag gagataatgg ttattttttt tttttttttt 200100 tttttgtttt tggtttttgt tatttggagt tgtgttttga agaggtatat tgggtattag 200160 gtttttttgg ttttgttttt attttttgtt tagatataga ataatttttt tttattttta 200220 aggttgatac gtggggttgt ggattaaagt taatttattt atttatgagg ggagtaattt 200280 ttttgtttta ggaatttgtt tttataggag aataaatatt gtagaaggta ttgtttttag 200340 tggtggtgta cgtttgtaat tttagttatt taggaggttg aggtagaaga attgttagaa 200400 tttaggaggt ggaggttgta gtgagttaat attatgttat tgtattttaa tttgggtgaa 200460 aagattaaga ttttgtttta aaataaaaaa agaatagtat tttgtgttaa ggttaggggt 200520 tttagttatt ttttttgtga agcggaaggg gtattattag tttttgtgag aaggaaatag 200580 tttatttaat tataaaatgt taattaaagg aggtagtata ttggttttgg tgcggtgtcg 200640 ttggtttttg tttggggtag gaggagggtt gggggagagt taaaagttaa agaaggttta 200700 tggaggtcgt tttttttttg gtgattagtt ttttttttga cggtaagttg ttaatagtat 200760 ttggttttta ggttggggaa ggtgagatta gtttatattt gtttagggtt ttgttttgtt 200820 tgtatgggta gtaggcgttt attttgttag atggttttgt ttattatagg gtattagtgt 200880 tagttaagga tttatagagt ttttttgtaa aggtttatta gtgggtattg ggattttggg 200940 ttttatttat atagggtttt tatataaaat ataggatgtt tagttaaatt tggattttag 201000 ataaataatt aataattttt tgaagagata aggattttgt tgttttattt aagttggagt 201060 ttagtggtat gattatggtt tattgtaatt ttgaattttt ggatttaagt aattttttaa 201120 ttgtagtttt ttaaagtatt gggattgtag gtatgagtta ttaaggttag taaataatga 201180 attattttta ggtataagta tattttaagt ttgttgtggg atatgtttat attaaaaatt 201240 aatttttgtt tatttgaaat ttaaattgaa tttattgtcg ggggagataa tggagtgatg 201300 gattgataga ggagtataga gatagttttt ttaaattttt agttgattaa agtttggttt 201360 ttagtttttt tgggttttta gagatgtatt aagggtggaa gcgattagga gggagataaa 201420 aatattgaag tttgagtgtt agtattgagt cgtgtggttt tggataggat tgtttttttt 201480 ttgagtttta gttttatatg ttataattgg ttaataatag ttataaagta ttcgaagtta 201540 atggttggga gtttgtttta ggaggtaggt attattagga tgtagagaga gtgaggagtt 201600 tttaaagtta gtttaggtta ggtatagtag tttatgtttg taattttagt attttgagag 201660 gttgaggcga gagaattatt tgagtttaga agtttaaggt tgtagtgagt tgtaattgta 201720 tcgttgtatt ttaggttgaa tgatagagtt tttgttttta aaataaaata aaataaaata 201780 aaataaaata ataaagttag tttgtgtatt ggattgtatg ttgttttaaa gtatttaaag 201840 tgagagaggt taggaagtaa tgagatgtag aaaggtaggg ggaggaggtt tagaggtatt 201900 agagaagata gttgattttt atttttatat atttttgggg tattttgagt tttatttata 201960 tatttaggtg agaatttttg tatttgtgaa agtaatttga ggtcgagaga attaatagga 202020 aatcgtttta ttttttatgt agggtttttt tataaataag gttgagtcgt agtttattat 202080 tgtagttgag ttttttgtag tagttgcggt ggggaaggtt ttttaggagg tttgagtaat 202140 ttagaaatat ttatagtata ttttttagtt tttttagagg tttttgttga gatgaaagtg 202200 ttttggttcg tggttaaaga gtttagtata ttgggtagtt atagttttta ttatattgat 202260 ttggttatta ggtttttatg aatttagtga ggggagatgg gttttttagg gaagtttgtt 202320 gattttttta tattgttgta aatgtaaagt ttggtgattt tattattttt agtaattgtg 202380 atgtagtaat aataagaata gttatgttta tcgtttattg aaggtatatg atgagttaga 202440 tattgtgttg gtatatgtga tttttggagg taatatattt ttttttaagg aggaaatgat 202500 tgagttttgg agggagggtt ttttatttgg ttttaggttt ttttttgatt tgcgtttttt 202560 tttttttttt cgtttgtttt attgtagttt ttttggtttt tttgttgttt ttggaatgta 202620 ttaagtttgt ttttagttta gtttttgtat tgttggtttt tttttgtttt tttaatttta 202680 atttagttgt tattattttt gtgatttttt attatttatt ttaaagtagt tattagttat 202740 tttttatgta attattttat tttaattttt attatagttt ttagttttat tttgatagtt 202800 tttagaattg atgaatttat tgattttgtt tttttttatt gtatgtaaat tttaagaaat 202860 aagagttttt gtttgtttat tgttgtgttt tagtgtttgt tatagtattt ggtatgtagt 202920 aggtgtttaa tgaatatatt tttaaaagaa tgaacgattg gaaggagttt gaaagaacga 202980 tggtttgtgt taatagttta tttttaattt ttttagacgg gatggagatt attattatgt 203040 aattacgatt tttttgagtt tgtgtggtgg ttgacggtag gtgttagttt ggttggatta 203100 agggatggtt ggtaacgtat cgtttttggg tgtgtttgtg agggtgtttt tggaggagat 203160 gggtatgtga gttggtgggt tgagtggtaa agattttttt ttaatatgga tgatattatt 203220 ttattgttag ataataaaaa ggtagagaaa aggtgaattt tttttttttt ttggaggtgg 203280 gatgtttttt ttttttgttt ttggatttag aatttttagt tttttagtag ttttttaggt 203340 ttttaaattt ttggttttaa attaagagtt atattaatag ttttttagtt ttgaggtttg 203400 tagatttgga ttgagttacg atattggttt ttttgggttt ttagtttgcg gacggttttt 203460 tgtggtatat tttggttttt ataatggtat gagttaattt ttttaataaa ttttttttta 203520 tttatttatt atttattttt ttaattgttt atttgtttat ttatttattt atttattatt 203580 tattttttat ttatttattt attatttatt taattaatgt atttatgttt gtttgtttat 203640 cggttattta tatttattta ttaattattt atttatttat tatttatttg ttatttattt 203700 agttatttat ttatttattt atttattttt tttttttttt tgagatggag ttttattttg 203760 tcgtttaggt tggagtgtag tggcgtgatt ttagtttatt gtaattttta ttttttaggt 203820 ttaagtgatt ttcgtgtttt agtttttcga gtggttggga ttatagatat gtattattac 203880 gtttagttaa tttttttatt tttagtagag atggggtttt attttgttag ttaggttggt 203940 tttaaatttt tggttttaag tgatttatcg gttttagttt attaatgtgt tggttattat 204000 aggtaagagt tattgaattt aatttattat ttgtttgttt gtttgtttgt ttgtttgtgt 204060 ttatttgttt gtttggttat ttattattta tttatttatt tgtttgtttg tttgtttgtt 204120 tgtttgtgtt tgtttgtttt tatttttttg tttgtttgtt tatttagtta tttgtttgtt 204180 tgtttgtttg tgtttgtttg tttttttttt tttttgttcg tttgtttgtt tatttagtta 204240 tttatttatt tatttatttt ttattggttg tttttttgga gagttttggt tgatgtagac 204300 ggtgttttgg taagtttagg ttgttattta gattattgtg gagggagtga tttaaataat 204360 agatatgtat tttttagttt gagaggttta aagtttcgga ttaaggtgtc gttagggtta 204420 gttttcggcg aggttttttt ttttggtttg tatttatttt tttgttgtgt ttttcgttat 204480 tttttttttg tttataagtg aggggggagg agagattttt ggtgtttttt ttttttttta 204540 taaggatatt aattttatta gattagggtt ttgttttatg attttattta attttaatta 204600 tttttttaaa agttttattt ttaattatag ttgtattggg agttagggtt ttaacgtagg 204660 aatttaaggg gaagggtata gtttggttta taataaatgg gaaattatgt ttatgattaa 204720 attttttaga agatatggtt tattagcgtc gttaatgatt gtaagtaaag gttagagagg 204780 aaaggggttt tcgtggggtg gggggcggtg ggggtagttg gtgtcgggaa taaggttttt 204840 ttttttgttt aatagtaggg aagtgaggtc ggttgtagat gttatttggg gtgggaagag 204900 aggggagttt ttgtttgtat attttgtgtg ggttttggtt tgattttttt tcgtgttttt 204960 tattttttgt gttttttttt gtgtgggaga aacgtcgatt tttgttggtt taggtgttta 205020 ggtttttagg tttgttggtt ttgggttggg tttaattaac gagaggtttg ggaggaattt 205080 gggaggtgga agtaagggag ggcgcgggag ttttttattt tttttgtttt agatagtttt 205140 tttagtagga gaggtggttt tttgtgtagt tttagttttt gttagagttt tatttttgtt 205200 tgggttttta gtaggtgatt ttggtttttg gattttggtt ataggatttt ttttttttta 205260 tttttattta ggggtggtgg tggtattttg ttgttaattt ttaggttatt tttataatgt 205320 taagaatttt ttttttattt gtatggtttt tttttaaggt attgagaagg gttttaatta 205380 tatgtttata gggttaaata ttttttgtaa aatttataaa atggaaaata ttttttttat 205440 aattaattaa cgttttcgtt tatttttagt tttgagtttt tgttcgttat attttttttt 205500 gtgtgaggtg gaaacggagg tttgttgtta cgtgggggtt tttgttaagg agaagttgaa 205560 ttggaaagat atttagtttg gttttggtcg ggttatattt atgtagtttt tatttatttt 205620 tatgtatagt ttagttattg ttcgttattt cggtgtggaa acggatttta gtaatattcg 205680 ttttatttat cgttttaatt ttatttatcg cgtagaatta aaaattataa gatacgaata 205740 tattttgcgg tgtttggcgt cggaaaaacg tgcgtagtgg agagaagtaa gatttgaaat 205800 gtacgggttt agaagtaaat ttgtggaaaa ttatttttat tattagaggt gaagttgtaa 205860 gtaaaggatt tagttttttt aatgtggagt taaaatagaa aagttttttt ggttagaaat 205920 atatgtataa atgttttata tgtagttaga aatttttttt atttttttat tttttttttg 205980 atgggaatta tatttaaaaa aaaagaaaaa aataggattt attagaattt ttgtgtattt 206040 tgaataaaat aattgtagta gtattattaa ttttatgttg atcgttattt ttgtatatat 206100 tttaattatt aaaaataaaa ataaaatttg attaattaag gagatttatt cgttttattt 206160 atttatttat ttttgagatg gagttttatt ttgttgttta ggttggagtg taatggtacg 206220 attttggttt attgtaattt ttgttttttg ggtttaagtt atttttttgt tttagttttt 206280 taagtagttg ggattatagg cgtgcgttat tatatttggt taatttttta tgtttttggt 206340 agagatgggg ttttattatg ttgattaggt tggttttaaa tttttgattt taagtgattc 206400 gtttatttta attttttata gtgttggaat tataggcgtg agttattacg tttagtttat 206460 gttttttttt gttgtttttt tttttttttt gagatatggt tttatttttt tatttaggtt 206520 ggagtgtagt ggtatgatta cggtttattg tagtttcgat tttttgggtt taagtaattt 206580 ttttatttta gttttttaag taattgggat tataggtgta tgttattatg ttttgttagt 206640 ttttgtattt ttagtagaga cggggtttcg ttacgttgtt cggatcggtt ttgaattttt 206700 ggttttaagt gatttatttg ttttggtttt ttaaagtgtt gggattatag gtacgagtta 206760 ttgtgtttag tttgattagt tttttgtttt cgaaatagaa aacgatatta taaagttatt 206820 atattgaaga agtaatgtta aaaatgtggg agaaatagaa ttttggagat atgattgata 206880 gttgattggt atttttttgt atgtagtgat gtttgtgata tttaatagtt gtttataatt 206940 tataatttgt tgttatttat ttttttattt taaatgaatt attgtattta tatttttaga 207000 gggttgtata agtttatatt attttgattt tttgttgatt gtttttttgt tttttgtttg 207060 gtttttattt tttttattat ttgtgtaatt agtttttcgt ttttaagttt ttttgtttta 207120 aatgtttaag tggattaggt attgtggttt tcgtttgtaa ttttagtatt ttgggaggtt 207180 taggtaggag gattatataa atttaggagt ataagattaa tttgggtaat atagtaagat 207240 tttgttttta tatatatata aaaaatataa aaattagtaa ggcgtgatgg tatatgtttg 207300 tagttttagt attttgggag gttgaggtag gaggattgtt tgaggttggg agtttaggat 207360 tagtttgggt aataaagtaa gattttgttt ttataaaaat aaaagaaaaa attaggtagg 207420 tatatagtgt gtatttatag ttcgagttat ttgggaggtt gagaagggag gatcgtttga 207480 gtttaggagt ttaaggttgt tatgagttgt gattatatta ttgtatttta gtttgcgtga 207540 tagagtgaga ttttgttttg ggaaaaataa ataaataaat aaataaataa ataaataaat 207600 aaatgtttaa gcggttttta ttttttggtt agattttatt atatatttta tgaataaatc 207660 gtatgtatga gaaaggtgag tagatgaata gggtagggtt agggggttaa ggggaagatt 207720 atagattacg tggagcgaga ttagtggtta aaaattgtta attatagtta ggtttggtgg 207780 tttatgaagg taattttaac ggtcgggttt ggtggtttat gttcgtaatt ttagtatttt 207840 gggaggtcga cgcgagttta ttatttgagg ttaagagttc gagattagtt cggttaatgt 207900 agggaaattt cgtttttatt aaaaatatta aaattggtta ggtatggtgg cgggcgtttg 207960 tagttttagt tatttgggag gttgaagtag gagaattggt tgaattcggg aggcggaggt 208020 tgtagtgagt tgggatttta ttattgtatt ttagtttggg cgatagagcg agattttatt 208080 ttaaaaaatt taaaaaaaaa aaaataaaaa attgtagatt ttaataagga agagttatag 208140 gacgatattt taggatgcgg gaaaaggtta cgttagtttt ggattttttt tgattaatgg 208200 gtattttagt tattaaaggg gtagatgcgt tttatttaat ttttatttag ttattagagt 208260 ataatatagg gatgtgttat agatagagat ggagattaat aggtagaggg gtgatgggga 208320 ggaagattga ggtaagagga ataaaacggg gattgtagag ggtaggtggt aggagtttga 208380 gggttttaga agaaattgtt gtataagtaa tgagttagta gggtgagtga cggttaggag 208440 aggtggttta agaaaataaa gagatatttt cgggggtata gatgcgtttt gaggggtcga 208500 ggaagagatg gggaaggggt ggttttgtgg attttcggta tgattgtcgt ggtgaaaagg 208560 aattaaagat ttcgataagg ggatgatttt ttaaataagg aagttttggg ttttcgtagg 208620 gggattagta gattgagggt aaacggtatt ttgtttatta aagttttaat aaaatgttaa 208680 ggtaagaata tttgtttggt tttgggggta attttagaaa tattagaaaa gggatttatt 208740 atgcgtaatt tttttttaat tatttggaga aatgtatggt tatttaagat agagaaaggt 208800 agttaaagta agtggaggtt aggtatagtg atttacgttt gtatttttag cgttttggga 208860 ggttgaggta ggaggatcgt ttgaggttgg aaatttagta ttagtttagg taataataaa 208920 ataagatttt gtcgttataa aaataaaaat aaaaattttt tgagacggag ttttattttt 208980 tttgtttagg ttggagtgtc gtggtacgat tttagtttat tgtaattttc gttttttaga 209040 tttaagtaat ttttttgttt tagttttttg agtagttggg attataggta tgtgttatta 209100 tgtttagtta attttgtagt tttagtagag atagggtttt tttatgttgg ttaggttggt 209160 ttcgaatttt cgattttttt ggttttttaa agtgttagga ttataggtat gagttatcgc 209220 gttcggttgt tataaaaatt ttttaaaaat tagttaggta tgttaggcgc ggtggttttt 209280 atttgtaatt ttagtatttt gggaggttaa ggtaggtgga ttacgaggtt aggagtttga 209340 gattagtttg attaatatgg tgaaatttcg tttttattaa aaatataaaa attagttagg 209400 tgtggcggta tatgtttgta atcgtagtta tttaggaggt tgaggtagga gaattgtttt 209460 aatttaggag tcgggggttg tagtgagtcg agattgtatt acggtatttt agtttgggta 209520 atagagtaag attttgtttt aaaaaaaaaa aaaaaaaaaa aattagttag gtatgtagcg 209580 tatatttgta gttttagtta tttaggaggt tgagaaggga ggattaattg aaattgggag 209640 gtcgagattg ggaggttatg attacgttat tgtattttaa tttgggtaat atagtaagat 209700 tttgtttaat aataataata ataaataatg taagtgggta taagaattta tttatttatt 209760 tatttattta tttatttatg agatagggtt ttattttgtc gtttaggttg gagtgtattg 209820 gcgtaatttc ggtttattgt aagtttcgtt tttcgggttt atgttatttt tttgttttag 209880 tttttcgagt agttgggatt ataggcgttc gttattgtat ttagttaatt ttttgtattt 209940 ttagtagaga cggggtttta ttatggtttc gattttttga ttttgtgatt tgttcgtttc 210000 ggttttttaa agtgttggga ttataggtgt gagttatcgt tttcggtttt aagaatttat 210060 tttattttag tattttggag gttgaggcga gtggattacg aggttagaag attgagatta 210120 ttttggttaa tatggtgaaa tttcgttttt attaaaaaaa tataaaaaat tagtcgggcg 210180 tgggggcggg tgtttgtagt tttagttatg cgggatgttg aggtaggaga atggtgtgaa 210240 ttcgggaggc ggagtttgta gtgagcggag atcgcgttat tgtattttag tttgggtaat 210300 agagcgagat tttattttaa aaaaaaaaaa aaaagaattt attttaagat agtaagtttt 210360 agggttgaag ttagttttta tttagtttta ggtttaaagt tataagtatg gttattgtaa 210420 tatttttatt taggatatta ttttttaggg gtttagattt atattattaa ggaggagcgt 210480 ttatattagt agttggggag agggtggttt tttataagat gtaatgttta ttttgaagag 210540 ttattatagt gataattatg aaatttatgt ttgagattta attttaagtg aaaagaatag 210600 aatttaatat ttattttatg gggagtataa aattttgaaa atatacgttt tttataatta 210660 aattaaattt tatgttatgt ttttgaggag ataagtattg aatggaatat agaagaaatg 210720 ttatagttaa tgattgttga agtttttttt ttaatttttt gtttatgttg tttggtaata 210780 agtaatatag aaaattgata ataaaaagta aaagagaaag aaaagatata gtgtatagtt 210840 tagattgttt tttttaaaaa attaaataat aataataaaa agtataggtc gggtgcggtg 210900 gtttacgttt gtaattttag tattttggga ggttaaggcg ggcggattat ttgaggtcgg 210960 gagttcgaga ttagtttgat taatatgggg atatttcgtt tgtattaaaa atataaaatt 211020 agtcgggtat ggtgacgtag gtttgtaatt ttagttattt gggaggttga ggtaagagaa 211080 tcgtttgaat tcgggaggtg gaggttgtag tgagttgaga tcgcgttttt gtattttagt 211140 ttgggtaata agagcgaaat tttattttaa aaaaaaaaaa aaaaaagtat aaatgtaagt 211200 tgggcgcggt agtttatgtt tgtaatttta gtattttggg aggtcggggt aggtggatta 211260 tttgaggtta ggagtttgaa attaattcgg ttaatatggc gaaattttat ttttattaaa 211320 aatataaaaa ttagttaggt atggtggcgc gtgtttgtaa ttttagttat ttaggaggtt 211380 gaggtaggag aattgtttga atttaggagg tagaggttgt agtgagttaa gattgagtta 211440 ttatatttta gtttgggtga tagagtgaga tttcgtttta aaaattaaat taaattaaat 211500 taaataaaat aaaaaaaaga agcggtataa tataaagttt cggtagttaa agcgttaatt 211560 tttagttatt aggaaggttt tgttatttaa tgatttatcg ttttagttaa ggttagttat 211620 attttgggtt tttgatgttg gaggtaatat gatgttaata ttggcgagaa atttattatt 211680 tttttttttt cgtttttcgg tgtcggtttt tgtgtgtatt tgtagttttt ttattatcgg 211740 tgtttttatg gtgtttacgt tatcggttta ttttttagta ataattcgat agttcgatat 211800 ttttgtagat tttgtggtta tagagttaaa gttttttgtt attagtgggt tttgtagata 211860 attttttaaa tttttttggg ttgagttagt taagttttta ataagttgga agatgatagg 211920 ggttggatgt aatttatttt taattggttt gggttatatg gatattattt tttttttggg 211980 atttgatttg ggatggaaat aggagttata gtttatggga aggttgtgaa aggaagtttc 212040 ggttttaggg tgcggattag gttgatttgc ggaataaggt tttaggggcg gtttattcgt 212100 ttgttttgtt tagttttttt tggtaattat atttattcgg ggtttatttt aaatttggta 212160 ggtaatgttg ttgtttttat tttagtcgtt gttttaatac gtttcgtttg gttaggatag 212220 gtgtttaggt atggtattta gggatatttt cggttttcgg ggtttaattt ttggttttta 212280 ggtgtagcgt tgggaaaagt agagggtttc ggttatggcg taggtttcgt tataggttat 212340 ttaagtagtt tgggaggagt cggaaagaga gtaatgtatt tatttggata gagattgaag 212400 ttatattttt attgagaaaa gatgatattt ttgtttggat tttttttttg aaattttagg 212460 tcggggtggg gtaggagtta gcgagagagt ttagcgtttt aaaggggatt ttttggtttt 212520 tcgtgttttt taatttagta tttttgggga tttatatatt tagggtagag tggttattta 212580 gggttttttt tatttagata taaaggttat tgaaggtttc gggttaatat cgttttgagg 212640 atgattagcg atttgagttt ttgttagaga tagtaggtag tttgggttta agggtcgttt 212700 agtgatttga agttgggatt attttatatt ttttgcgtta tttttgtttt ttgttttgga 212760 ggtttttagg ttgttaatag ttatgttttg gagaattagg ttagattagg ttgggaataa 212820 agtttagttg ttatagagtt gtcgagaggt tattggtaag tagtgtttag gagtcgtttt 212880 ttttttgtta gtaatagttt aatgtttttt tttatagggg ttgtaaatgg gtttatgttt 212940 agggtggggt tagggagata aagtagagag aaattgggtt gggagtagag agtgttatgt 213000 tttattttgg agatttaagg ttaggttatt ttgtagagtt ggtgtttaga gtttttagcg 213060 tataggagag gaggtaaata gaatttgata tttagtagcg ttcggtagac gtttttggaa 213120 tgaatgatta aatttatatg gagagttgaa atgggttagg aattttaggg agacgggtag 213180 tttatagttt agtagggtcg ttttagtaga gtaggttaat gttaggtttt ttggtaaatt 213240 tttcggggtt taggtataat tgttatatta ggaaaggggt aggggtgatt agtttatcgg 213300 ttacgggggt attttattgt ttttatagaa gttcggtatt tataggtttg ggtgatatac 213360 gatttttatg tttggtatta cgatggttgt ttattaagtt tttttattta ttaggattga 213420 ttttttttgg ttagcgattt tagattatta tgatttggta gttgtcgtta ggtttgtttg 213480 gttaaggatt ttttcggaga ttgagttatt ttatatagta aagtgagtta tggggttata 213540 gcgttgtgtg ttgtgtataa gtttcgaggg ttttatttag ggattggtat ttattgattt 213600 ttataaattt ttggtaatcg tttagagttg ggatgttttt aaggtaatag ttttaataaa 213660 tagaggcgta ggaatttagc gcgttatttt tcgttttatt ttaaaggttt atatttttag 213720 gggtttggag tttttttttg gagttttttt tattttaaag ttagttggat ttgtttagga 213780 attgttatta ttattttttg gtcgggtttg tattgatgtg tattgaattt tttttattag 213840 gtttatttta ggtaaatttt agagtttacg taatattgtt tgtggataaa tattggggcg 213900 gaaatagggg ttatttttag gttttagtta tatggggttg ttagggttgt ttgggatggt 213960 aggagagtgt tagaggaggg tagtttaagg attaggtagg gggtgggaag tgtttttttt 214020 tatgggtttt taagtgagat gttttttgta aatatttatt tgggattttt aagtagaggg 214080 ttggttttta tgttatttgg atttggattt tagattattg tttttaagtg gtaattttgg 214140 gtttttttgt atttgttttg gtttgagttg gttatatttg tggggggtgg ttttaggaag 214200 aaggtggatt gtcgtaaacg taatgtttcg ttgttaggtg tattgttttc ggttattaga 214260 atttttttgg gtaggtcggg gagatttgac gggtaagtgt ttgcggtttg gcgtgagcgg 214320 gtagggtagg tggtttttgt ttgggtatgt ttttttattt ttgtaataga ttagggagag 214380 ggttggtttt aggatttagg tttagttagt tgttttataa ttgaggggtt tcggcggagg 214440 atataagtta gatagagtta tagattaatc gtacgaggtg gttttttttt tttagtttag 214500 gttttttgaa tgcgttagag tagataagtt tggacgtgag gaggtaagag gtagcgagaa 214560 taggcgcgga gacggggttg ggggagaaga ggaagaaatt ttgtgtttgt gtttttttta 214620 cgttcgtttg ttatcgggtt agttgattgg ggaagtgttt tttgagggtg taattttttg 214680 tttttttcgt aagttagttt tcggggcgtt gggtgagggt gtagttttgt ttattacggc 214740 gagttagtat attgaattac ggtagaagtt gttttttgtg tgggtgtagt tttttttttt 214800 gtttaggatt tagaagttac gatagtatag agttttttaa tcgtggttgg tgttttttta 214860 ggaatttttt gaaagttata gagaaatttt agagtggttg ggtacggtgg tttatgtttg 214920 tgattttagt attttgggag gttgaggcgg gtggattatt tgaggttcgg agttcgagat 214980 tagtttggtt agtatggtaa aattttattt ttattaaaaa atataaaaat tagttgggta 215040 cggtggtata tgtttgtaat tttagttatt taggaggttg aggtatgaga attgtttgaa 215100 tttgggaggt agaggttgta gtgaatcgag atcgtgttat tgtattttag tttgggtaat 215160 agagtaagat tttattttaa aaaaataaaa aataaaaaaa gaatttttag agtaattttt 215220 aggtgttagt aggggtgtga cgtaatttta gtttcgtttt tgtggtttat cggtttcggg 215280 taagtttttt tgtcgttgtt atttatagag agtttttagg ggagtttggg aatgacggta 215340 agttttatgt gatttagtat gtaaagggag ttttaaaatt tagaatttag agagttaggg 215400 cgggtatagt gtagttggtt ttagtgttga ggggttgggg gagagatttt gtattatgtt 215460 ttgattatag taagggaaga ttatggaggt ttttggaacg ttttagtaat ggcgtaattt 215520 tagttttttt tatttttttg ttaatgataa ttatgattat gatagtagtt aataggttat 215580 agagtaggta ttttttagtt tttttaaata tgaattcgtt taatttttat aataatatag 215640 tattgtttta tttaataaat gaggtaggtt gggcgtggtg gtttatgttt gtaattatag 215700 tattttggga ggttaaggta ggtagattac gaggttagga gttcgagatt agtttgatta 215760 atatggtgaa attttatttt tagtaaaaat ataaaaatta gttgggcgta gtggtacgtt 215820 tttataattt tagttattta ggaggttgag gtaggagaat tatttgaatt tgggaggcgg 215880 aggttgtagt aagttgagat tatgttattg tattttagtt tgggagatag agtgagattt 215940 cgttttaaaa ataaataaat aaataaaatt aaaaaatatt atatatataa aaaaataaat 216000 gaggtaaatg agatgtatga ggtgagaatt ttgtgttata gggagaggcg tagtttggtg 216060 agatttaatt ttaaggggtt ggcggttttg agtttttaag tgtaattatt ggattatatt 216120 gtttgtagat tattattatt tttattttat tggaaggtcg ggtgaggtaa tcgggaaagt 216180 ttggagtagt agtggagttg ttagagagaa tttgttttta gtgttttttt ggattttgta 216240 gttgttttgt gtgggttttt gttgtttttc gtattggaaa agattttttt atagatgggg 216300 ttttatgacg ttatttaggt tggagtgtcg tgtttatttt taggcgttgt tatagggttg 216360 tagttttgaa tttttggttt taagcgattt ttttgtttta gttttttgag tagttttttg 216420 ggtttaagcg attttcgtgt tttagttttt tgagtagttt tttgggttta agcgattttc 216480 gtgttttagt tttttgagta gttgggattt taagcgtatt tggttaagtt tttttttatt 216540 ttttattatt taagattttt ttttttttaa ggtttagttt aattttattt ttatttaaaa 216600 ttttcggggt atttttgtag tatttggagg ttgaattgtt taggagggaa gggtgttaat 216660 gagttggtgt ttcgttttta ttttgatttt cggtgagaat gtaagttttt tgtaggtaag 216720 gattatattt tattattatt tttgtattta tttagatttg gttatgtgtg tttagtatat 216780 aaagtgtttt cgatgattgt ttatagattt acggtatttg agattgtttt aatatatttt 216840 tttaaaattt tttttttttt tagaggttta cgaatgttta aattaggttt atcgggaata 216900 atattatggt tatttcgttt attttgaagt ttatatatag gtttggaagt aataatttcg 216960 tatagtttag atgaaaaaat aaagattttt ttgttgtttt tggattgtta gagttttggg 217020 ggatttttaa tattttttgt tgtttttttt aattttatgg tgtcgatggt ttgttggggg 217080 gttagtttga tttttgcgag tgttcgtatt cggaaaaggg ttggtgttaa gatagtttta 217140 ggatatttag aatgagggta agaggttatt tttattatta gtttttttta gttttatttt 217200 atataattgt aatatagtga tttagtatat tttgggttat tgttaagtag ggagtaaatt 217260 agaaatggtt tgagtttttt ttttttttat ttttagaggg gtttgttttt ttaggtaaat 217320 ataaggaggt atcgaggttg ttgtataaga gttggttttt gtttatttta taaattttat 217380 ttttatttat tgtaaaaggt tttgtttttt tttttaaaaa aaaaaaaaaa aaagaaattt 217440 agtgaggggt ggggtaggtg tgtgtggagg agaggagaaa aggataagtg atggtttttt 217500 tattttttag taagtcgtag gtgtagagat tttaagtttg ttttagggtt ttttcggtat 217560 ttgtgtagga gggttttcgt agaaaaaatt taggatttac gatttgggag gatttcggtt 217620 atttttattg tttggattta ttagtgggag gtaaagtgta agaaattaag ggtaaagggt 217680 tttttttggg cgggttagag attttttgga aagggttatg tatcgcgcga tttttataat 217740 aattttaagt atttggagta tgttggggag gaagtttcgg tgttaaaatt aagtatgtgt 217800 tatttggaag ttcgttttcg tttattagta tattaattta tttacgtttt tgatagagtt 217860 gtgtttcggg tgcgtagagg gttattttgt tcgtaataat cgggtgaaag ttgaaatttt 217920 aagttattga tttagaaggg tattttcggg gaagttttga gtaatttttt ttgagataag 217980 gtattttatt atttattttg gtttttaaat atggaaagtt agaggaaatc gataatggtt 218040 taaaggtagg gggatggttt cgatgatttt tttattttta attaaggttt atgattttgt 218100 ttttttatta ataaaaatta atttatggat ttttggtagg tattttttta tttgaatgaa 218160 ttaaaggagg gatattaaat aaacggtttt tagatttaga agaggagacg ttatttataa 218220 tttgaggatt gaggaggata aaggattttg tttgtttgga ttttttggag aaaattataa 218280 aggaaaaaaa aaaggaagga aaagataaat aatgaagatt tggatttttt ttaatttgtt 218340 tttgtggttt cggtgtgttt atttgtgaaa tggaatttta gagtgttaga gcgggagttt 218400 tttatgaaat gaaagttttt gaatcggttt atggtgaggt ttaagttagg tttttttcgt 218460 ttatttaagg cgggttttgt tagggtggag tgaggatgtt agtcgcgggc ggcgttttga 218520 gcgtaaaacg tgaattcgag tcgttaagtt tgggcgttgt tggacggttt tatttggagg 218580 tcgtttcgtg ttttattaag tagaggagaa atcgaagaga attcgaagaa aggatgttgc 218640 ggtttggatt attagtttta gaggttgaat ttaaggatat ttttttattt agtttcgatt 218700 ttatttattt atatagacgt atagggattt aaagtattcg gtcgatttgg aaagttagcg 218760 atttttgcga gggtgtaagg ggcgaggaag agggagcgtt ttttagggta gttttttcga 218820 tattcgagta agggttggag atagcgtagg ggacggtcgg tttaggtcga aagcggttcg 218880 atagcggttt tgttttggga ggaattcgat ttgtagtgtg ttcgtcgcgg ggattcgttt 218940 agtttcgggg gcgtttcgtt attttcggtc gtaggtattt aggtgagtag cgttggtttc 219000 gggatatcga ttttttttta tttcgggcgc gaagtttatt tgagtaagat ttttttatgg 219060 tgttttcgtg gtcgtcgttt ttaggaaagt gtggcggcga ggtagcgggg cgcgcgtttt 219120 tagggcgtta attttgggtc ggtagtagga aggcgggaag agggggcggt tcgtcgtttg 219180 gagtgtatcg atcgggtttc gtttcggttt cgttttcgtt tcgttttttt tcggagatgc 219240 gtatagaatt tcggtttagt cggttgtggt ttcgtttttg attcgttttt ttttcgtttc 219300 gtgaacgtgc gcgtcgagtt ttattttcgt ttatttttgc gttgcgttgt atttggcgga 219360 gcggggttgg cgggcgtcgg gtttgggagg gggcgttttc gcgcggtagc gtagattaga 219420 ttagattagg ttaggtcggg ggtgggggtc gtttgcgtgg ttcgtcgcgt tcgtagtttt 219480 gtatttttag tttttcgcgt tggcgttaat ggttggtttc gggagtcgtc gtatttttta 219540 gtttcgagtt cgggcggggc gggttcggtt aggtggaagc gggcggaggt gcgggcgttt 219600 cgggcggttt cgtcgggcga ggcggcggcg tcgggtatcg cggcggcgtc gggtatagtc 219660 gggggtcgga gtcggggtgt cggtttagtg ggtcggggta gggcgggata ggatatttgt 219720 tttgttattt ttttggtaat taaaagggta gagtgcgtcg attgagttgg agttttagtt 219780 tttttatttg taaatgggcg cgttggatag atgattattt gttttttttg cgttgggtat 219840 cgtgcgtagt tcggtgtatc ggtgtagcgg ggtagatata gggagtcgtt ttttataatt 219900 cgggtaacg 219909 <210> 6 <211> 1405 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 6 cgttattcga gttgtaaagg gcggtttttt gtgtttgttt cgttgtatcg atatatcgag 60 ttgcgtacgg tgtttagcgt agggagaata aatgattatt tgtttaacgc gtttatttat 120 aggtgaggaa attaaggttt taatttaatc gacgtatttt gtttttttga ttattagaaa 180 agtagtagga taggtgtttt gtttcgtttt atttcggttt attaagtcgg tatttcggtt 240 tcgattttcg gttgtgttcg gcgtcgtcgc ggtgttcggc gtcgtcgttt cgttcggcgg 300 ggtcgttcgg agcgttcgta ttttcgttcg tttttatttg gtcgggttcg tttcgttcgg 360 attcgggatt gggaagtgcg gcgattttcg gaattagtta ttggcgttag cgcggggagt 420 tgggggtgta gagttgcggg cgcggcgggt tacgtaggcg gtttttattt tcggtttggt 480 ttggtttggt ttggtttgcg ttgtcgcgcg ggggcgtttt tttttaggtt cggcgttcgt 540 tagtttcgtt tcgttaggtg tagcgtagcg taggggtggg cgggggtggg gttcggcgcg 600 tacgtttacg gggcggggag ggggcgggtt aggggcggga ttatagtcgg ttgggtcggg 660 gttttatgcg tattttcggg gaggggcggg gcgggggcgg ggtcggggcg gggttcggtc 720 ggtgtatttt agacggcggg tcgttttttt ttttcgtttt tttattatcg gtttaggatt 780 agcgttttgg gagcgcgcgt ttcgttgttt cgtcgttata tttttttggg agcggcggtt 840 acggaggtat tatgaagaag ttttatttag gtgggtttcg cgttcggggt ggggaggggt 900 cggtgtttcg ggattagcgt tgtttatttg agtgtttgcg gtcgggagtg gcgaggcgtt 960 ttcggagttg agcgagtttt cgcggcgggt atattgtagg tcgagttttt tttaggatag 1020 ggtcgttgtc gggtcgtttt cgatttgagt cgatcgtttt ttgcgttgtt tttagttttt 1080 gttcgagtgt cggaggggtt gttttggggg acgttttttt tttttcgttt tttgtatttt 1140 cgtaggaatc gttgattttt taggtcggtc gggtgttttg ggtttttgtg cgtttgtgtg 1200 ggtgaatggg gtcggggtta ggtggagggg tgtttttggg tttagttttt agggttggtg 1260 gtttaggtcg tagtattttt ttttcggatt tttttcggtt ttttttttat ttagtggggt 1320 acgggacggt ttttagatgg gatcgtttag tagcgtttaa atttggcgat tcgggtttac 1380 gttttgcgtt taggacgtcg ttcgt 1405 <210> 7 <211> 1405 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 7 gcgggcggcg ttttgagcgt aaaacgtgaa ttcgagtcgt taagtttggg cgttgttgga 60 cggttttatt tggaggtcgt ttcgtgtttt attaagtaga ggagaaatcg aagagaattc 120 gaagaaagga tgttgcggtt tggattatta gttttagagg ttgaatttaa ggatattttt 180 ttatttagtt tcgattttat ttatttatat agacgtatag ggatttaaag tattcggtcg 240 atttggaaag ttagcgattt ttgcgagggt gtaaggggcg aggaagaggg agcgtttttt 300 agggtagttt tttcgatatt cgagtaaggg ttggagatag cgtaggggac ggtcggttta 360 ggtcgaaagc ggttcgatag cggttttgtt ttgggaggaa ttcgatttgt agtgtgttcg 420 tcgcggggat tcgtttagtt tcgggggcgt ttcgttattt tcggtcgtag gtatttaggt 480 gagtagcgtt ggtttcggga tatcgatttt tttttatttc gggcgcgaag tttatttgag 540 taagattttt ttatggtgtt ttcgtggtcg tcgtttttag gaaagtgtgg cggcgaggta 600 gcggggcgcg cgtttttagg gcgttaattt tgggtcggta gtaggaaggc gggaagaggg 660 ggcggttcgt cgtttggagt gtatcgatcg ggtttcgttt cggtttcgtt ttcgtttcgt 720 tttttttcgg agatgcgtat agaatttcgg tttagtcggt tgtggtttcg tttttgattc 780 gttttttttt cgtttcgtga acgtgcgcgt cgagttttat tttcgtttat ttttgcgttg 840 cgttgtattt ggcggagcgg ggttggcggg cgtcgggttt gggagggggc gttttcgcgc 900 ggtagcgtag attagattag attaggttag gtcgggggtg ggggtcgttt gcgtggttcg 960 tcgcgttcgt agttttgtat ttttagtttt tcgcgttggc gttaatggtt ggtttcggga 1020 gtcgtcgtat tttttagttt cgagttcggg cggggcgggt tcggttaggt ggaagcgggc 1080 ggaggtgcgg gcgtttcggg cggtttcgtc gggcgaggcg gcggcgtcgg gtatcgcggc 1140 ggcgtcgggt atagtcgggg gtcggagtcg gggtgtcggt ttagtgggtc ggggtagggc 1200 gggataggat atttgttttg ttattttttt ggtaattaaa agggtagagt gcgtcgattg 1260 agttggagtt ttagtttttt tatttgtaaa tgggcgcgtt ggatagatga ttatttgttt 1320 tttttgcgtt gggtatcgtg cgtagttcgg tgtatcggtg tagcggggta gatataggga 1380 gtcgtttttt ataattcggg taacg 1405 <210> 8 <211> 2365 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 8 gtggtcgtgg tgggggtgtt agttgtaggg gtgttttcgg tgggtgggag ttggtggttt 60 ttcgttggtg ttatgggatt cgtatgttcg ttttgcgttt ttcggttttt gagtttatag 120 gtcgggattt tgtttgttag tcgcgtgcgt tgtcgtttaa tttttgtagg cgtagagcgc 180 gcggcggcgg tgatagagaa ttttgtttgg ttgtttaaat atagtttttt gtagaaggat 240 tttgcgttcg gggaagggga ggaatttttt tttttttggg cgttcgtttt tttcgttatg 300 gttcggtttt tatattcgtt tatatttggt cgtagcgggg cgttcggggg gaggggttga 360 ggtcgcgttt ttcgtcgttt tttgggcgcg ggttaggcgg ggaggagggg ggcgtttcgg 420 tcgtgtgttt aggattgttt tttagcggtt attcgggttt tagtttttta ggtttggttt 480 tgataggcgg gcggagtagt tagtgcgaga tagggaggtc ggtgcgggtg cgggaatttg 540 attcgttcgg gaggcggggg cggggcgggg gcgtagcgcg cggggagggg tcggcgttcg 600 tttttttttt ttatttattt agttgagtta gggggtttag gggttttttc ggcggttagt 660 tttgtattgt aggagcgcgg gcgcggcgtt ttagttagcg cgtagggttc gggtttcgtc 720 gggggcgttt tttcgtcgtt gtttttcgcg cgattcgttg tttattagtt attatgtcgg 780 atttcgcggt taacgcgtag ttggatggga ttatttcgga tttcgaaggt gggtgttggg 840 ttggttgttg cggtcgcgga cgtgttggag aggattttgc gggtgggttt ggcgcgggac 900 gggggtgcgt tgaggggaga cgggagtgcg ttgaggggag acgggatttt taatttaggc 960 gttttttcgt tgagagcgtc gcgcgttttc ggtttcgtgt tcgcgtcgtt tacgtggggg 1020 attttgttag gggtattcgc gtagattttg cgcgttttta taggattttg tgttcgtttt 1080 gcgtattgtc gtttgggttt tttttttttt attgttgttt gtgtttgtta agcgatagcg 1140 attttttcga gggttcgcga ggttgtttcg gaatttttta ggacgtatag ttttattttg 1200 ggaaatttat cggttttttt tttttggttt ttttcggcgg ttttcgggtt tcgtttggat 1260 tcggtaacgg gatagggagg tcgtttttta ttttcgattg agtggatagt cgcgttttgt 1320 tcgggtggat agtttttttt ttttttacgt tagtttcggg gtcgttaagt tgtgtagttc 1380 gtgggtcggg agtatcgaac ggatatagtt taggtcgtgg tagggtttag agtgggatgt 1440 tttatggttt ttatttaggt ttggggatat ttttattcgt tttttagaat cgggtcgtgg 1500 gggatagaag gggtttgcgt gcgggtaggg agagtatttt ggtttttttt tgttttcggg 1560 gtttataaag tgtgttggga tttgcggggt tgttttgttt aagtttgggt ttggcgttcg 1620 cgtttttgag tttgtgagtg cgtgcgtttt tttgcgtttt tttgattgtc ggtgttgggg 1680 ttttgcgttt tgcgttcgcg ggagtaaata tagtaggcga aggggaagtt tatataatgg 1740 tttttagcgt tttggggtag ggtttttgag gggcgggttt gtttttgtcg ggatttggag 1800 ttttcgtttt tcggagaggt ttttaggttg atttgggtag agttttttgg tgggtcggga 1860 gggggaaagg ttgtgttgaa atgagtaaat tgtttaggtg ttaggttaag ttgggaggtg 1920 attagtttga ggtttttttc gttttatggt tagaattagg gttgatattt gggtgttttg 1980 agtttagttg tttatacggt ttatttgggg ttagttttat ttgagtgggg gaggcggggt 2040 tttttggggg attagaattt tggttggacg ttaagtagag tgttagtggt tgttttttag 2100 ggttgggttt gaggagggtg tggggcggcg aagggacggg agggggttgt gatttagtgg 2160 ttattggcgt tgtgtagagt gtgagttgga aatatcgtag ttattttgtt agtttagtgg 2220 tgaaagtttt tttttaggtt ttattttttt gtatttttgt tttttagagg gaggggaggt 2280 ttgggtttgt agagttggga gggtttgttg ttttcgtttt ttttttttat aatatttttt 2340 tatttggata tttttgggta tatgt 2365 <210> 9 <211> 2365 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 9 gtatgtgttt aaagatgttt agatgaggag gtgttgtggg ggaggggggc gggaatagta 60 agttttttta gttttgtaga tttagatttt tttttttttt gggaagtagg gatgtaaagg 120 gatagagttt gaaaaagggt ttttattatt aagttgataa agtaattacg atgtttttag 180 tttatatttt gtatagcgtt agtggttatt ggattataat tttttttcgt tttttcgtcg 240 ttttatattt tttttaggtt tagttttgaa gaatagttat tggtattttg tttggcgttt 300 agttaaagtt ttggtttttt aggaggtttc gtttttttta tttagatagg gttgatttta 360 ggtgggtcgt gtgggtagtt gggtttagga tatttagatg ttagttttgg ttttggttat 420 ggagcgggga ggattttagg ttggttattt tttagtttgg tttgatattt ggatagtttg 480 tttattttaa tatagttttt ttttttttcg gtttattaga gggttttgtt taagttagtt 540 taggagtttt ttcgaggggc gggggtttta ggtttcggta gaggtaggtt cgttttttag 600 aagttttgtt ttagagcgtt ggagattatt gtgtgagttt ttttttcgtt tgttgtattt 660 attttcgcgg acgtaggacg tagagtttta gtatcggtag ttaagaggac gtaggaaagc 720 gtacgtattt ataggtttag agacgcggac gttagattta ggtttggata gagtagtttc 780 gtaagtttta atatattttg taaatttcga agataggaga gagttaaaat attttttttg 840 ttcgtacgta ggtttttttt gttttttacg gttcgatttt gggaggcgga tgaggatatt 900 tttaggtttg gatgggggtt atgggatatt ttattttaga ttttgttacg atttgggttg 960 tgttcgttcg gtgttttcgg tttacgggtt gtataatttg gcggtttcga aattggcgtg 1020 ggggagggga gggttgttta ttcgagtagg acgcggttgt ttatttagtc ggaggtgagg 1080 aacgattttt ttatttcgtt gtcgggttta agcggggttc gagagtcgtc ggggagagtt 1140 aaagggaggg gatcgatgga ttttttagag tgaaattgtg cgttttggag agtttcgagg 1200 tagtttcgcg agttttcgag gaggtcgttg tcgtttggta aatataaata ataataaaag 1260 gaaggaaatt taggcggtag tgcgtagaac gagtataggg ttttgtgagg gcgcgtaggg 1320 tttacgcggg tgtttttaat agggtttttt acgtaggcgg cgcgggtacg gggtcggggg 1380 cgcgcggcgt ttttagcggg agggcgtttg gattaggggt ttcgtttttt tttagcgtat 1440 tttcgttttt ttttagcgta ttttcgtttc gcgttaggtt tattcgtagg gtttttttta 1500 gtacgttcgc ggtcgtagta gttagtttag tatttatttt cgaagttcga aatgatttta 1560 tttagttgcg cgttgatcgc ggggttcgat atgatggttg gtgggtagcg ggtcgcgcgg 1620 agggtagcgg cgaggaagcg ttttcggcgg ggttcgggtt ttgcgcgttg gttggggcgt 1680 cgcgttcgcg tttttgtagt gtagagttag tcgtcggagg agtttttagg ttttttggtt 1740 tagttgaatg aatgggggag gaaggcgggc gtcggttttt tttcgcgcgt tgcgttttcg 1800 tttcgttttc gtttttcggg cggattaggt tttcgtattc gtatcggttt ttttgtttcg 1860 tattggttgt ttcgttcgtt tgttaaggtt aggtttgggg ggttggggtt cgagtggtcg 1920 ttgggggata gttttgggta tacgatcgga gcgttttttt ttttttcgtt tggttcgcgt 1980 ttaggggacg gcgagagacg cggttttagt tttttttttc gggcgtttcg ttgcggttag 2040 atgtgggcgg atgtggaggt cgggttatgg cgaggagggc gggcgtttag aggggaagag 2100 attttttttt tttttcgggc gtagggtttt tttgtaggag gttgtatttg ggtagttaaa 2160 taaagttttt tgttatcgtc gtcgcgcgtt ttgcgtttgt aagggttaaa cggtagcgta 2220 cgcggttggt aggtaggatt tcggtttgtg ggtttaagag tcgaggggcg tagggcgaat 2280 atgcgagttt tatggtatta gcgagaggtt attaattttt atttatcgag ggtatttttg 2340 tagttaatat ttttattacg attat 2365 <210> 10 <211> 219909 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 10 tgttatttga gttgtaaagg gtggtttttt gtgtttgttt tgttgtattg atatattgag 60 ttgtgtatgg tgtttagtgt agggagaata aatgattatt tgtttaatgt gtttatttat 120 aggtgaggaa attaaggttt taatttaatt gatgtatttt gtttttttga ttattagaaa 180 agtagtagga taggtgtttt gttttgtttt attttggttt attaagttgg tattttggtt 240 ttgatttttg gttgtgtttg gtgttgttgt ggtgtttggt gttgttgttt tgtttggtgg 300 ggttgtttgg agtgtttgta tttttgtttg tttttatttg gttgggtttg ttttgtttgg 360 atttgggatt gggaagtgtg gtgatttttg gaattagtta ttggtgttag tgtggggagt 420 tgggggtgta gagttgtggg tgtggtgggt tatgtaggtg gtttttattt ttggtttggt 480 ttggtttggt ttggtttgtg ttgttgtgtg ggggtgtttt tttttaggtt tggtgtttgt 540 tagttttgtt ttgttaggtg tagtgtagtg taggggtggg tgggggtggg gtttggtgtg 600 tatgtttatg gggtggggag ggggtgggtt aggggtggga ttatagttgg ttgggttggg 660 gttttatgtg tatttttggg gaggggtggg gtgggggtgg ggttggggtg gggtttggtt 720 ggtgtatttt agatggtggg ttgttttttt tttttgtttt tttattattg gtttaggatt 780 agtgttttgg gagtgtgtgt tttgttgttt tgttgttata tttttttggg agtggtggtt 840 atggaggtat tatgaagaag ttttatttag gtgggttttg tgtttggggt ggggaggggt 900 tggtgttttg ggattagtgt tgtttatttg agtgtttgtg gttgggagtg gtgaggtgtt 960 tttggagttg agtgagtttt tgtggtgggt atattgtagg ttgagttttt tttaggatag 1020 ggttgttgtt gggttgtttt tgatttgagt tgattgtttt ttgtgttgtt tttagttttt 1080 gtttgagtgt tggaggggtt gttttggggg atgttttttt ttttttgttt tttgtatttt 1140 tgtaggaatt gttgattttt taggttggtt gggtgttttg ggtttttgtg tgtttgtgtg 1200 ggtgaatggg gttggggtta ggtggagggg tgtttttggg tttagttttt agggttggtg 1260 gtttaggttg tagtattttt tttttggatt ttttttggtt ttttttttat ttagtggggt 1320 atgggatggt ttttagatgg gattgtttag tagtgtttaa atttggtgat ttgggtttat 1380 gttttgtgtt taggatgttg tttgtggttg atatttttat tttattttag tagggtttgt 1440 tttaagtagg tgaagggggt ttgatttggg ttttattatg agttggttta ggagttttta 1500 ttttataaga ggtttttgtt ttggtatttt gaagttttat tttatagatg ggtatattga 1560 ggttataagg gtaggttaag agaaatttag atttttatta tttgtttttt tttttttttt 1620 tttttttttt tgtggttttt tttaaaggat ttaggtaggt aggatttttt gtttttttta 1680 gtttttaaat tataaatagt gttttttttt ttaaatttag aaattgtttg tttaatgttt 1740 tttttttaat ttatttagat agaaaggtat ttgttaagga tttatgaatt aatttttatt 1800 gataggagaa tagaattatg ggttttagtt ggaggtgaag gagttattgg ggttattttt 1860 ttgtttttgg gttattgttg gttttttttg gttttttata tttaggaatt aaaatgagtg 1920 ataaagtatt ttgttttaaa gaggattatt tagaattttt ttgaaaatat ttttttgggt 1980 tagtagttta gaattttaat ttttatttgg ttgttgtgaa taagatggtt ttttatgtat 2040 ttggagtata gttttgttag gagtgtgggt gggttggtgt gttggtgggt gggagtgggt 2100 ttttaggtgg tatatgtttg gttttggtat tggggttttt tttttaatat gttttaaata 2160 tttgagattg ttgtggggat tgtgtggtgt atggtttttt ttaggggatt tttagtttgt 2220 ttagggaggg ttttttgttt ttggtttttt atattttatt ttttattggt gggtttagat 2280 agtgggggtg attggggttt ttttaggttg tgggttttgg gttttttttg tggagatttt 2340 tttgtataga tgttggaagg gttttgaggt aggtttggag tttttgtatt tgtggtttat 2400 tgggaggtgg ggagattatt atttgttttt tttttttttt ttttatatat atttatttta 2460 ttttttattg ggtttttttt tttttttttt ttttaaaaaa aaggatagaa ttttttgtag 2520 taggtggaag tagagtttgt ggagtgagta ggaattaatt tttgtatagt agttttggtg 2580 tttttttgtg tttatttaaa ggggtaggtt tttttgagga tgggggaagg gagggtttag 2640 attatttttg gtttgttttt tgtttggtag tggtttaagg tgtgttgggt tattgtgttg 2700 tagttgtatg gagtgggatt ggagggggtt gatggtgggg gtggtttttt gtttttattt 2760 tgagtgtttt ggagttgttt tggtattagt ttttttttgg gtatgggtat ttgtaggagt 2820 taggttgatt ttttaataag ttattgatat tatgaaatta aggaaagtag taaaagatgt 2880 taaaaatttt ttaaggtttt gataatttaa ggataatagg aaggttttta tttttttatt 2940 tagattgtgt gggattattg tttttagatt tgtatgtggg ttttagaata aatggaatga 3000 ttataatgtt gtttttggta gatttggttt gaatatttgt gagtttttga aaaggagaaa 3060 gattttagaa ggatgtgttg gggtaatttt aagtattgtg ggtttataga tagttattga 3120 agatatttta tgtgttgggt atatatggtt aagtttgagt gggtatagaa atggtaatga 3180 gatatagttt ttgtttgtag agaatttata tttttattgg gagttaggat gagggtgaga 3240 tattagttta ttaatatttt ttttttttga gtagtttagt ttttaaatat tataggaatg 3300 ttttggaggt tttaggtgga ggtgagattg agttgggttt tgaggaagga gaagttttga 3360 gtagtggaga ataaaaaggg atttggttag gtgtgtttga agttttagtt atttaggagg 3420 ttgagatatg aggattgttt gagtttagga ggttatttag gaggttgaga tatgaggatt 3480 gtttgagttt aggaggttat ttaggaggtt gagataggag gattgtttga agttaggagt 3540 ttaaggttgt agttttgtga tagtgtttgg aaatagatat ggtattttag tttgggtggt 3600 gttatgagat tttatttgta agaaggtttt ttttaatgtg gaaggtagta agggtttata 3660 tagggtagtt gtaggattta gggggatatt ggggataggt tttttttggt agttttattg 3720 ttgttttagg tttttttgat tgttttattt ggttttttaa tggggtggag gtagtggtag 3780 tttataggta gtgtggttta gtggttatat ttgggggttt agagttgtta gttttttggg 3840 attaaatttt attaggttgt gttttttttt gtggtataag gtttttattt tatgtatttt 3900 atttgtttta tttgtttttt tgtgtgtgtg gtgtttttta attttattta tttatttatt 3960 tttgagatgg agttttattt tgttttttag gttggagtgt aatggtatga ttttagttta 4020 ttgtaatttt tgttttttag gtttaagtga tttttttgtt ttagtttttt gagtggttgg 4080 gattgtagga atgtgttatt gtgtttagtt aatttttata tttttattag agatggggtt 4140 ttattatgtt ggttaggttg attttgaatt tttgattttg tgatttgttt gttttggttt 4200 tttaaagtgt tgtgattata ggtatgagtt attatgttta gtttgtttta tttgttaaat 4260 gggatagtgt tatgttgttg taaaggttaa atgagtttat atttgaaaaa gttgagaaat 4320 gtttgttttg taatttgtta gttgttgtta tgattatgat tgttattgat aggaggatgg 4380 agaaggttgg ggttatgtta ttgttaggat gttttagaag tttttatgat ttttttttat 4440 tgtggttaga gtatggtgta gggttttttt tttagttttt tagtattgga gttagttgta 4500 ttgtatttgt tttggttttt taggttttga gttttgggat tttttttgta tattaggtta 4560 tatggaattt gttgttattt ttaggttttt ttggaaattt tttgtgggtg gtagtggtag 4620 gaggatttat ttgaggttga tgagttatag aagtgggatt gaggttgtgt tatattttta 4680 ttggtatttg ggaattattt tggagatttt ttttttattt tttatttttt tgagatggag 4740 ttttgttttg ttgtttaggt tggagtgtag tggtatgatt ttggtttatt gtaatttttg 4800 ttttttaggt ttaagtaatt tttatgtttt agttttttga gtagttggga ttataggtat 4860 gtgttattgt gtttagttaa tttttgtatt ttttagtaga gatggggttt tattatattg 4920 gttaggttgg ttttgaattt tggattttag gtgatttatt tgttttagtt ttttaaagtg 4980 ttgggattat aggtatgagt tattgtgttt agttattttg gagttttttt gtggttttta 5040 ggagattttt gaaggggtat tagttatgat taaaaagttt tatgttgttg tgatttttga 5100 gttttgggta gggagggagg ttgtatttat ataggaagta gtttttgttg tgatttagtg 5160 tgttggtttg ttgtggtgga tagggttgta tttttattta gtgttttggg agttgattta 5220 tgggaagggt aaggaattgt atttttagag aatatttttt tagttagtta atttggtgat 5280 aggtgagtgt gggaagggta taagtatagg gttttttttt tttttttttt agttttgttt 5340 ttgtgtttgt ttttgttgtt ttttgttttt ttatgtttaa gtttgtttgt tttggtgtat 5400 ttaggggatt tggattggag agaaaaagtt attttgtatg gttagtttgt ggttttgttt 5460 gatttgtgtt ttttgttgag gttttttagt tgtgagatag ttggttgagt ttaagttttg 5520 gggttagttt tttttttagt ttgttgtaaa ggtagaaagg tatgtttagg taggggttat 5580 ttgttttgtt tgtttatgtt agattgtagg tatttgtttg ttagattttt ttggtttgtt 5640 tagagggatt ttgatagttg agggtaatgt atttggtagt ggagtattgt gtttgtgata 5700 gtttattttt tttttggaat tattttttat aagtgtgatt agtttaagtt aggataggta 5760 tagggggatt taggattgtt atttaggggt agtggtttgg aatttaggtt taggtgatat 5820 gggagttaat tttttgtttg gagattttag gtgggtgttt gtagaggata ttttatttga 5880 ggatttatgg aaggggatat tttttatttt ttatttggtt tttgggttgt ttttttttga 5940 tatttttttg ttattttagg tagttttgat agttttatgt gattgggatt tagaggtggt 6000 ttttgttttt gttttagtgt ttgtttatag gtagtgttgt gtgggttttg aagtttgttt 6060 aagatggatt tgataagggg agtttagtat atattagtgt aggtttggtt agggggtgat 6120 gatggtagtt tttgggtaga tttagttggt tttagggtag gaggggtttt agagagaggt 6180 tttaggtttt taggggtgtg aatttttggg gtgaggtggg aagtgatgtg ttgggttttt 6240 gtgtttttgt ttgttggagt tattattttg gaaatatttt agttttaggt ggttgttagg 6300 gatttatggg gattagtggg tgttaatttt tgggtgaagt ttttggggtt tgtatatagt 6360 atatagtgtt gtggttttat ggtttatttt gttgtgtgaa gtggtttagt ttttgggaga 6420 gtttttagtt aggtaggttt gatggtaatt gttaggttat ggtgatttgg aattgttgat 6480 taaagggagt tagttttggt gggtggaggg atttggtggg tagttattgt gatgttaggt 6540 atggggattg tgtgttattt aggtttgtgg gtgttgagtt tttgtgggag tagtgaagtg 6600 tttttgtggt tgatgggttg gttatttttg tttttttttt gatgtgatag ttgtgtttgg 6660 gttttgggaa atttgttagg aggtttggta ttggtttgtt ttattggagt ggttttgttg 6720 agttgtgagt tgtttgtttt tttgaggttt ttagtttatt ttaatttttt atgtggattt 6780 ggttatttat tttagaagtg tttgttgggt gttgttgagt gttaggtttt gtttgttttt 6840 ttttttgtat gttggaggtt ttgggtatta gttttgtagg gtggtttggt tttgggtttt 6900 tagggtagag tatggtattt tttgttttta gtttagtttt tttttgtttt atttttttga 6960 ttttattttg ggtatgggtt tatttgtagt ttttgtgaag ggagatattg agttgttgtt 7020 ggtagaggag gggtggtttt tgggtattgt ttgttaatgg ttttttggta gttttgtgat 7080 agttgagttt tgtttttagt ttaatttgat ttggtttttt aaagtatgat tgttggtagt 7140 ttgaaaattt ttaggatagg aaataggagt ggtgtaggga atgtaagatg attttagttt 7200 taagttattg ggtggttttt agatttaggt tgtttgttgt ttttggtagg aatttaagtt 7260 gttggttatt tttagagtgg tgttggtttg gggtttttag tggtttttgt gtttgggtga 7320 gaggaatttt ggatggttat tttgttttga gtgtgtgggt ttttagaagt gttgggttag 7380 ggggtatgga gggttagaaa gttttttttg gagtgttgga tttttttgtt gatttttatt 7440 ttattttggt ttggggtttt agagaagggg tttaggtagg agtgttattt ttttttaatg 7500 gggatgtggt tttagttttt gtttaggtgg gtgtattgtt ttttttttgg ttttttttag 7560 gttgtttaaa tgatttgtga tgaggtttgt gttatggttg gggttttttg ttttttttag 7620 tgttgtattt gggaattagg ggttgggttt tggaagttga ggatgttttt gaatgttatg 7680 tttgggtatt tgttttggtt aggtgaggtg tgttggggta gtggttgaga tgggagtagt 7740 agtattgttt gttaggtttg agatgggttt tgggtgagtg tggttattag gaagggttgg 7800 gtagagtagg tgggtgggtt gtttttgggg ttttgttttg tagattaatt tgatttgtat 7860 tttggggttg gggttttttt ttatagtttt tttatgaatt atggtttttg tttttatttt 7920 aaattagatt ttagaagagg aataatgttt atgtaattta agttagttgg aagtgggtta 7980 tatttaattt ttgttatttt ttagtttgtt aaggatttga ttaatttaat ttagagggat 8040 ttggagggtt gtttgtaaaa tttattaata atagggaatt ttagttttgt agttataggg 8100 tttatagagg tgttgggttg ttgggttatt gttgggaggt gagttggtgg tgtagatatt 8160 atggaggtat tggtagtgga agagttgtaa gtgtatatag aggttggtat tgaggggtgg 8220 ggaggaggag gtggtggatt ttttgttagt gttggtatta tgttgttttt agtattagag 8280 atttaaggtg tggttgattt tggttggggt gatgagttat tggatagtag agtttttttg 8340 gtagttgggg gttaatgttt taattgttgg gattttgtat tatgttgttt tttttttttg 8400 ttttgtttgg tttggtttgg tttggttttt gagatggagt tttattttgt tatttaggtt 8460 ggagtgtggt ggtttaattt tggtttattg taatttttgt tttttgggtt taagtaattt 8520 ttttgtttta gttttttgaa tagttgggat tataggtatg tgttattatg tttggttaat 8580 ttttgtattt ttagtagaga tggggttttg ttatgttggt tgggttggtt ttaaattttt 8640 gattttaggt gatttatttg ttttggtttt ttaaagtgtt gggattatag gtatgagtta 8700 ttgtgtttag tttgtattta tgtttttttt tttttttttt tgagatggag ttttgttttt 8760 gttgtttagg ttggagtgta aaggtgtgat tttagtttat tgtaattttt attttttggg 8820 tttaagtgat ttttttgttt tagtttttta agtagttggg attataggtt tgtgttatta 8880 tgtttggtta attttgtatt tttagtatag atggggtgtt tttatgttgg ttaggttggt 8940 tttgaatttt tgattttagg tgatttgttt gttttggttt tttaaagtgt tgggattata 9000 ggtgtgagtt attgtatttg gtttatgttt tttattatta ttatttaatt ttttaaggaa 9060 agtaatttaa attgtatatt gtattttttt tttttttttt gttttttgtt gttagttttt 9120 tgtattattt attgttaaat aatatgaata ggaaattgaa aggaaaattt taataattat 9180 tggttgtagt attttttttg tgttttattt agtgtttgtt tttttaggaa tatgatatag 9240 ggtttgattt aattatgaaa ggtgtatatt tttagagttt tatatttttt atagaatgaa 9300 tgttgaattt tgtttttttt atttgaaatt agattttagg tatggatttt atgattatta 9360 ttataatggt tttttagagt ggatattgta ttttgtaggg aattattttt tttttagttg 9420 ttggtgtgga tgtttttttt tgatggtgtg ggtttgggtt tttgaagggt ggtgttttga 9480 gtaaagatgt tatagtagtt atgtttatag ttttgggttt ggggttaggt ggagattggt 9540 tttaatttta gagtttgttg ttttaaaata aatttttttt tttttttttt tgagatggag 9600 ttttgttttg ttgtttaggt tggagtgtag tggtgtgatt tttgtttatt gtaagttttg 9660 ttttttgggt ttatattatt tttttgtttt agtattttgt atagttggga ttataggtat 9720 ttgtttttat gtttggttaa ttttttgtat ttttttagta gaggtggggt tttattatgt 9780 tagttaggat ggttttaatt ttttgatttt gtgatttatt tgttttagtt tttaaagtgt 9840 tgggataaaa taaattttta gggttgggag tggtggttta tatttgtaat tttagtattt 9900 tgagaggttg aggtgggtag attataaggt tagaagattg agattatggt gaaattttgt 9960 ttttattaaa aatataaaaa attagttggg tgtagtggtg ggtgtttgta gttttagtta 10020 tttgggaggt tgaggtagga gaatggtatg aatttggaag gtggagtttg tagtgagttg 10080 agattgtgtt agtgtatttt agtttgggtg atagagtgag attttgtttt ataaataaat 10140 aaataaataa ataaataaat aaatttttat atttatttgt attatttatt attattatta 10200 ttaaataggg ttttgttgtg ttgtttaggt tggagtgtag tggtgtgatt atgatttttt 10260 agttttgatt ttttagtttt aattggtttt ttttttttag ttttttgagt agttgggatt 10320 ataggtgtgt gttgtatgtt tggttaattt tttttttttt tttttttttg agatagagtt 10380 ttattttgtt gtttaggttg gagtgttgtg gtgtaatttt ggtttattgt aatttttggt 10440 ttttggatta aagtaatttt tttgttttag ttttttgaat agttgtgatt ataggtatgt 10500 gttgttatat ttggttaatt tttgtatttt tagtagggat ggggttttat tatgttggtt 10560 aggttggttt taaatttttg attttgtgat ttatttgttt tggtttttta aagtgttggg 10620 attataggtg ggagttattg tgtttggtat gtttggttaa tttttaaaaa atttttgtag 10680 tagttgggtg tggtggttta tgtttgtaat tttagtattt tgggaggtta aggaggttgg 10740 gagtttgaga ttagtttgat taatatggag aaattttgtt tttattaaaa ttataaaatt 10800 agttgggtat ggtggtatat gtttgtaatt ttagttattt aggaggttga ggtaggagaa 10860 ttgtttgaat ttaggaggtg ggggttgtag tgagttgaga ttgtgttatg gtattttagt 10920 ttgggtaaag agagtgaaat tttgttttaa aaaatttttg tttttgtttt tgtagtgata 10980 gggttttgtt ttgttgttgt ttaggttggt attgaatttt tagttttaag tgattttttt 11040 gttttagttt tttaaagtgt tgggagtata ggtgtgagtt attgtgtttg gtttttattt 11100 gttttggttg tttttttttg ttttaggtaa ttatatattt ttttaggtaa ttaagaaaag 11160 attgtgtatg atgagttttt tttttggtat ttttgggatt gtttttaaaa ttagataagt 11220 gtttttattt tgatatttta ttaagatttt aatgaataga atgttgtttg tttttagttt 11280 gttggttttt ttgtgaaggt ttagggtttt tttgtttgaa aagttatttt tttgttgagg 11340 tttttgattt ttttttatta tggtagttat gttgagggtt tatagagtta tttttttttt 11400 attttttttt tggtttttta agatgtattt gtatttttgg agatgttttt ttgttttttt 11460 gggttatttt ttttggttgt tatttatttt gttgatttat tatttgtgta atagtttttt 11520 ttggaatttt taggtttttg ttatttattt tttgtagttt ttgttttgtt ttttttgttt 11580 tagttttttt ttttattatt tttttatttg ttggttttta tttttgttta tggtatattt 11640 ttgtgttata ttttgatggt tggataaagg ttgagtgaaa tgtatttatt tttttggtga 11700 ttggggtgtt tattaattag aagggattta aggttggtgt agtttttttt tgtattttgg 11760 ggtattgttt tgtggttttt ttttgttgga gtttgtagtt ttttgttttt ttttttttaa 11820 attttttgag atggagtttt gttttgttgt ttaggttgga gtgtagtggt gagattttag 11880 tttattgtaa tttttgtttt ttgggtttaa ttaatttttt tgttttagtt ttttaagtag 11940 ttgggattat aggtgtttgt tattatgttt ggttaatttt ggtattttta gtagagatgg 12000 ggttttttta tattggttgg gttggttttg aatttttgat tttaggtgat aggtttgtgt 12060 tggtttttta aagtgttgag attatgggta tgagttatta ggtttggttg ttgagattat 12120 ttttataagt tattaggttt ggttgtagtt ggtagttttt gattattggt tttgttttat 12180 gtgatttgtg attttttttt tggttttttg gttttgtttt gtttatttgt ttattttttt 12240 tatgtatgtg gtttgtttat agggtatgta atggggttta attaggaaat ggaaattgtt 12300 tgagtattta tttatttatt tatttattta tttatttatt tatttttttt aagataaggt 12360 tttattttgt tatgtaagtt gaagtgtagt ggtgtgatta tagtttatgg tagttttgaa 12420 tttttgagtt taagtgattt ttttttttta gttttttaag tagtttggat tataggtgta 12480 tattatatgt ttgtttaatt ttttttttta tttttgtaga gatagggttt tgttttgttg 12540 tttaggttgg ttttgaattt ttaattttaa gtaatttttt tgttttagtt ttttaaagta 12600 ttggagttat aggtatgtgt tattatgttt tgttaatttt tgtatttttt gtgtgtgtgt 12660 aaagataagg ttttattatg ttgtttaggt tggttttgta tttttgggtt tatgtgattt 12720 ttttgtttgg gttttttaaa gtgttgggat tataggtggg agttatagtg tttggtttat 12780 ttgagtattt agaatagaag gatttaaagg tggggaatta gttatataga tgatgggaga 12840 ggtgaaggtt agatagggaa tagagaggta attagtagga aattaaagtg gtgtgggttt 12900 atatagtttt ttaaaggtat ggatgtaatg atttatttag aatgagaaaa taaataatag 12960 taaattataa attataagta gttgttaaat attataaata ttattatatg tagaagagta 13020 ttagttaatt gttagttata tttttaaagt tttatttttt ttatattttt ggtattattt 13080 ttttaatatg atgattttgt aatattgttt tttattttga gaatagaaaa ttgattaggt 13140 tggatatagt ggtttgtgtt tgtaatttta gtattttggg aggttaaggt aggtggatta 13200 tttgaggtta ggagtttaag attggtttgg gtagtgtggt gaaattttgt ttttattaaa 13260 aatataaaaa ttagtagggt atggtggtat atatttgtag ttttagttat ttaggaggtt 13320 gaggtgggag gattgtttga gtttaggagg ttgaggttgt agtgagttgt gattatgtta 13380 ttgtatttta gtttgggtga gagagtgaga ttatgtttta aaaaaaaaaa aaaaataata 13440 aaaaaaaata taggttgggt gtggtggttt atgtttgtaa ttttagtatt gtgggaggtt 13500 gagatgggtg gattatttga ggttaggagt ttgaaattag tttggttaat atggtgaaat 13560 tttattttta ttaaaaatat aaaaaattag ttaggtgtga tgatgtatgt ttgtaatttt 13620 agttatttgg gaggttgagg taggagaatg gtttgaattt aggaggtaga ggttgtagtg 13680 ggttaagatt gtgttattgt attttagttt gggtaataga gtgagatttt attttaaaaa 13740 taaataaata aataaagtga atgaattttt ttagttgatt aaattttgtt tttatttttg 13800 gtagttggga tgtatataaa agtggtggtt aatatggagt tggtggtgtt gttataattg 13860 ttttgtttaa gatatatagg aattttggta aattttgttt tttttttttt ttttaaatgt 13920 gatttttatt aagaaagaag taggaaaatg ggggagattt ttaattgtat atgaggtatt 13980 tgtgtatgta tttttgatta gagagatttt tttgttttga ttttatattg aaggaattga 14040 attttttgtt tataatttta tttttggtga tgggagtaat tttttataga tttgtttttg 14100 gatttgtgta ttttaaattt tgtttttttt tattgtgtat gtttttttgg tgttaggtat 14160 tgtaggatat gtttgtgttt tgtgattttt gattttgtgt ggtaggtgga attggaatgg 14220 tgagtggagt gagtattgtt ggaatttgtt tttatattgg gatagtgagt agtaattgaa 14280 ttatatatgg aaataaatgg gaattatata aatataattt gattaaagtt aaattaaata 14340 tttttttagt ttaatttttt tttagtagga gtttttatgt ggtagtaagt ttttgttttt 14400 attttatata agagaaaatg tgatgggtag gaatttaaga ttggaaatga atggggatgt 14460 taattgattg tagggaaaat attttttatt ttgtaaattt tataaaaaat gtttgatttt 14520 gtggatatgt ggttagggtt ttttttagtg ttttgagagg gaattatgta ggtagaggga 14580 gggtttttag tattgtgggg gtgatttgga gattggtagt agggtgttat tattattttt 14640 aggtggggat gagagggagg aagttttgtg attagagttt aggggttaga gttatttgtt 14700 gggagtttaa ataaaggtgg gattttggta ggagttggaa ttatatagag gattattttt 14760 tttgttggag aagttgtttg aggtagagga ggtggagagt ttttgtgttt ttttttgttt 14820 ttatttttta ggtttttttt aagttttttg ttggttgaat ttagtttaaa gttagtaggt 14880 ttggggattt ggatatttga gttagtagag gttggtgttt tttttatata aaggagggta 14940 taagaagtgg gaggtatgga gggggattag gttaggattt atataggatg tgtaaatagg 15000 agtttttttt tttttttatt ttaaatggta tttgtagttg gttttatttt tttgttgtta 15060 gataggaaga ggaattttgt ttttggtatt agttgttttt attgtttttt attttatgga 15120 ggtttttttt ttttttggtt tttgtttgta attattggtg atgttgatgg attatatttt 15180 ttggggagtt tggttatgaa tatggttttt tatttgttgt ggattaaatt gtgttttttt 15240 ttttgaattt ttgtgttgaa gttttaattt ttaatgtagt tgtaattgaa gatagggttt 15300 ttagggaggt aattaaggtt aaatgaagtt atagggtagg attttaattt aataggattg 15360 atgtttttat aagaagaggg agagatatta gagatttttt tttttttttt atttgtaaat 15420 agaggaaaaa tgatggagga tatagtaggg aggtgggtat aagttaggaa gaggggtttt 15480 gttgggaatt aattttgatg gtattttgat ttgggatttt gggtttttta aattgagaaa 15540 tatatgtttg ttgtttaagt tatttttttt atagtaattt ggatggtagt ttgagtttat 15600 taaggtattg tttgtattag ttagggtttt ttagggagat agttaatagg agatggatgg 15660 atggatggat ggttagatag atagataagt ggatagagag agagagagat aggtagatat 15720 agatagatag gtagataaat ggttagatag ataagtagat agagagatag agatagatag 15780 atataaatag gtaaatagat aggtagataa atggatagat agatgataga tagttaggta 15840 ggtagataga tatagatagg tagatagata gatagataga tgataggttg ggtttagtga 15900 tttttatttg taataattag tatattggta ggttgaggtt ggtggattat ttgaggttag 15960 gagtttgaga ttagtttggt taatagggtg aaattttatt tttattaaaa atagaaaaat 16020 tagttgggtg tggtggtgta tgtttgtaat tttagttatt tgggaggttg aggtatgaga 16080 attatttgaa tttgggaggt ggaggttgta gtgagttgag attatgttat tgtattttag 16140 tttaggtgat aaagtgagat tttattttaa aaagaaaaaa aagatagata gatgaatgga 16200 tagatagtta gatagatgat agatggatga taggtagata gataattgat aaatagatat 16260 aaatgattga tggataggta gatatagata tattgattag gtagatgata gatggataga 16320 tagaagatag atggtggatg ggtgggtaga taggtagata gatagttaga aagatagatg 16380 atagatagat aggaaggaat ttattagggg aattggttta tattattgtg gaggttaaga 16440 tgtattatag aaggttgttt gtaagttgga ggtttaggaa agttagtatt gtggtttagt 16500 ttaagtttgt aggttttagg attgggaagt tgttgatgta atttttagtt taaggttaaa 16560 ggtttgagag tttggggaat tgttggagaa ttgggagttt taagtttaag ggtaggagag 16620 gaaggtattt tatttttagg agaaagaggg aatttatttt ttttttgttt ttttgttgtt 16680 tggtaatgga atggtgttat ttatattgag ggaggatttt tattatttag tttattaatt 16740 tatatgttta ttttttttag aaatattttt atagatatat ttagaagtga tgtgttatta 16800 gttatttttt aatttagtta aattgatatt tgttgttagt tattatatag gtttagaaga 16860 attgtggttg tatggtgatg gtttttattt tgtttaaaga agttgaagat gaattgttgg 16920 tataagttat tgttttttta ggtttttttt agttgtttat ttttttaaaa atgtatttat 16980 tgagtatttg ttgtatgtta ggtgttgtga taagtattgg ggtatagtag tgagtaaata 17040 aggatttttg ttttttggag tttatatgta gtagaaggaa atagaattaa tgaatttatt 17100 agttttagaa attattaaaa taggattaag agttgtggtg agaattaaga taaggtgatt 17160 gtatagaaag tgattgatgg ttgttttgga atgagtggtg aggggttata gagatgatga 17220 tagttgagtt gagattggga agataggaag gagttagtag tgtaaggatt aggttggaag 17280 taagtttggt gtattttagg aatagtaagg aggttagagg ggttgtagta gagtaggtga 17340 ggaggaggag ggagatgtag gttaaagagg agtttggggt tagatggagg attttttttt 17400 taaagtttag ttattttttt tttaaaggag aatgtgttat ttttaaaagt tatatatgtt 17460 agtatagtgt ttggtttatt atatgttttt agtaggtggt gagtatggtt gtttttgtta 17520 ttattatatt ataattatta ggaataatgg agttattagg ttttgtattt atagtaatgt 17580 gagggagtta gtaagttttt ttggggaatt tatttttttt tattaagttt ataagagttt 17640 gataattagg ttaatgtagt gagagttata gttgtttagt gtattggatt ttttagttat 17700 gggttaggat atttttattt tagtagaaat ttttaagggg attggggagt gtgttgtgga 17760 tgtttttggg ttatttagat tttttgggga gtttttttta ttgtagttgt tgtagggagt 17820 ttagttgtag tgatgaattg tggtttagtt ttgtttatgg gaaaatttta tatgggagat 17880 gggatggttt tttgttggtt tttttggttt taggttgttt ttataagtgt agggattttt 17940 atttgggtgt gtgaatgggg tttaggatgt tttaagggta tgtggagatg ggggttagtt 18000 gttttttttg atgtttttga attttttttt tttgtttttt tgtattttat tgttttttgg 18060 ttttttttat tttgggtgtt ttggaataat atgtaattta atatataggt tgattttatt 18120 attttgtttt gttttatttt attttatttt ggaaataaag gttttgttat ttagtttgga 18180 gtgtagtggt gtaattgtaa tttattgtag ttttgaattt ttgggtttaa gtgatttttt 18240 tgttttagtt ttttaaagtg ttgggattat aggtatgagt tgttgtgttt ggtttaggtt 18300 ggttttaaaa gttttttatt ttttttgtat tttgatgata tttatttttt ggagtaggtt 18360 tttagttatt ggttttggat attttgtagt tattattggt tagttgtggt atgtgaagtt 18420 gaggtttagg agaagggtag ttttgtttaa ggttatatgg tttagtgtta atatttagat 18480 tttagtgttt ttattttttt tttggttgtt tttattttta gtgtattttt ggaggtttaa 18540 gggagttaaa ggttaggttt tggttagtta agaatttaaa aaagttgttt ttgtgttttt 18600 ttgttaattt attattttat tatttttttt gataatgaat ttagtttgaa ttttagataa 18660 ataaggatta atttttagta taagtatatt ttataataga tttgggatat atttatgttt 18720 aaaaatgatt tattgtttgt tggttttagt agtttatgtt tataatttta gtgttttggg 18780 aggttatagt tggagaattg tttgagttta ggagtttaag gttatagtga gttatgatta 18840 tgttattgag ttttagtttg ggtgaagtag taagattttt atttttttaa aaaattgttg 18900 attgtttatt tgaaatttag gtttaattga gtattttgta ttttatatga gaattttata 18960 taggtgagat ttagagtttt aatgtttatt ggtaagtttt tgtagggagg ttttgtgggt 19020 ttttggttgg tattgatgtt ttgtgatgag tagggttatt tggtaaggtg gatgtttgtt 19080 gtttatgtag gtagagtaag gttttgggta ggtatgagtt gattttattt tttttagttt 19140 gggagttaga tattgttggt agtttgttgt taagagaggg gttggttatt aagagagggg 19200 tggtttttat gggttttttt tggtttttgg ttttttttta gttttttttt tattttaaat 19260 agaggttaat ggtattgtat tagaattagt gtgttgtttt ttttggttgg tattttgtag 19320 ttgggtagat tgtttttttt ttataggagt tggtggtgtt ttttttgttt tatagggagg 19380 atggttgaga tttttgattt tgatataggg tgttgttttt tttttgtttt gagatagagt 19440 tttggttttt ttatttaggt tggagtgtag tggtatgatg ttggtttatt gtagttttta 19500 ttttttgggt tttagtaatt tttttgtttt agttttttga gtagttgaga ttataggtgt 19560 gtattattat tgagaataat gttttttata gtgtttattt ttttgtagga gtaagttttt 19620 aaggtaagga ggttgttttt tttatggatg aataaattga ttttgattta tagttttatg 19680 tgttagtttt gagggtgggg aaaggttgtt ttgtgtttag gtagggggtg ggggtaaggt 19740 taggagggtt tggtgtttag tgtatttttt taggatataa ttttaggtag tagaggttaa 19800 ggatagaggg gaggagaaga gggaggtggt tattattttt ttattttagt tttttttgga 19860 gataagtttg agtattttag ttgtttatta agtttggaga taagtttgga atttaaattt 19920 ttgattttga tttagttttt tatagttttt gtgagtaaat tgagttttag aaaaagggag 19980 tgaagtttgt gtattttgga tgtttttatt ttaggtttaa attgttttta ttttaggttt 20040 aaattgtttt tattttagtt taaattgttt ttattttagg tttaaagtgt ttttatttta 20100 gtttaaagtg tttttatttt aggtttaaag tgtttttatt ttaggtttaa agtgttttta 20160 ttttaggttt aaattgtttt tattttagtt taaattgttt ttattttagt ttaaattatt 20220 tttaatatag gtttaaatta tttttaattt aggtttaaag tatttttatt ttaggtttaa 20280 agtattttta ttttaggttt aaagtgtttg taatttaggt ttaaagtgtt tttattttag 20340 tttaaattgt tttattttag gtttaaattg tttttatttt aggtttaaat tatttttatt 20400 ttaggtttaa attgttttta ttttaggttt aaagtgggaa ggagttatag ggaaataaat 20460 gggggaggta tggatgatta ggatgagggt ttttatgatt tatttttttt taggggttat 20520 tttaagagtt ttttaaattt ttattatttt ttaatagaga tggggttttg ttgtgttgtt 20580 taggttgatt tttaattttt agttttaagt tattttttta ttttagtttt ttaaattgtt 20640 gaggttatag gtgtgagtta ttgtatttgg ttttttttag gagttttaag aaaaaaaatg 20700 ggaatagatt tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgttttga 20760 gaaagagttt tgttttgtta tttaggttgg agtgtaatgg tatgattttg gtttattgta 20820 atttttgttt tttgggttta agtgtttttt ttgttttagt tttttgagta gttgggatta 20880 taaatatgta ggttgatttt gtatttttat tagagatggg gttttattat gttggttagg 20940 ttgattttga attttggatt ttagatgatt tgtttgtttt ggttttttaa agtgttggga 21000 ttataggttt gagttattgt gtttggttag gaatagattt ttttttgtag atgatttttg 21060 ttattattga aaatggatgt ttatgtataa ttgaattgtt ataatgtttt attttaaaaa 21120 gttttttttt gagaaaatgt gatttttgat agaggagaga ttgtttaggt tttatttatt 21180 gttagtataa aggtagagta ggggtgtggt ggtgttattt ttttttgaga tagttttatt 21240 tttgttttgt ttaggggttt agaagtttgg tttatttgag tttatagagg ggtttggagt 21300 ggttgtttta tattataggt ggggtttgta aggatttgaa atgatttttg agaaggtggg 21360 tgtggtgggt gtattttaat tattaaagta ataataatga tatattaaat agtgtttgtt 21420 tagattttga gtgtttgttt aaatattttt attttgtgat ttgttagatt ttagtataat 21480 aatttaggta aaagaaaaaa tagttgggtg tggtggtttg tgtttgtaat tttagtgtga 21540 ggttaaggta ggaggattgt ttgagattag gagtttgaga ttagtttggg ttatttgaga 21600 ttttattttt gaaaataaat aaattaataa aagattttta tgttttatgt tttttttata 21660 tttaggtttt ttaaattata tgtattgggg aaagtttatt aagagaagtt tttggttggg 21720 tgtggtggtt tatgtttgta attttagtat tttgggaggt taaggtggga ggattataag 21780 gttaggagtt tgagattagt ttggttaata tggtgaaatt ttatttttat taaaaatata 21840 aaaattagtt gggtgtggta gtgtatgttt gtaattttag ttatgtagga ggttgaggta 21900 ggagaattat ttgaatttgg gaggtagagg ttgtagtgag ttaagttggt gttattgtat 21960 tttagtttgg gtgatagaaa aagattttat ttttaaataa ataaataaag ggagagaagt 22020 ttttgggttt ttagatatat gggttagtgt ttatttttgt aaagttgttg tgtttaaaga 22080 ggggttgtat ttggtggaat tggggtaaaa gagtagggag ggtattgggt agttgatttg 22140 gtttttatta ttggaaaggg gttgtgttgt tggtgttttg agttggtttt ataaggaaga 22200 tattgtatag ggtgttttaa gtttgttttt tttgtttagg tttatttttt tttttttagg 22260 attagggagt tttgtttgtt ttttgttttt ggtatttgtt ttttggtttg tgagtattgt 22320 attttttttt gtttggaatg ttggtttatg gtgggttttt ggatttttgt tttttgttgt 22380 tttttgttat attttgttaa agtgtgtttt atttatttat tgttattatt ttttgaaata 22440 gagttttgtt ttgttgttta ggttggagtg taatggtgtg attttggttt attgtaattt 22500 ttgttttttg ggtttaagtg atttttttgt tttggttttt tgagtagttg ggattatagg 22560 tgaatgttat tatgtttggt taatttttgt atttttagta gagatggggt ttttttatgt 22620 tggttaggtt ggttttgaat tgattttggg tgattggttt atgttagttt tttaaattgt 22680 tgggattata ggtgtgagtt attatgtttg gttaattatt ataatattga tattataata 22740 atattatagt tagataatgg tgattaatgt ttgtaatttg aatattttgg gaggttgagg 22800 taggtagatt atttgaggtt agtttgagat tagtttggtt aatgtggtga aattttgttt 22860 ttattgaata tataaaaatt agttggagtg tgatggtagg tgtttgtaat tttagttatt 22920 tgggaggtgg aggttgtggt gaattgagat tgtgttattg tagtttaatt tgggtgatag 22980 agtaagattt tattttaaaa gtagtaataa taataataat aataataata ttatttattg 23040 agttttaatt ttgtgttagg tattgtgtta gtatttgtgt tatgtgattt tattgatttg 23100 gaataattta tgagtaagta ttatttttgt ttttaaggaa gttgagattt aggaaatgga 23160 agttattttt tagggtttat agtaagggtt tggtgaggtt tgtgtttaaa ttttgattat 23220 ttgattttag gtttttttgt tttttttgtt ttttaaaaat ttaaatattt ttatttggga 23280 tgattttaga tagttagatt ttaattgttt tttttttttt tgagtatgtt ttattttaaa 23340 attatataaa gataatttat tttttaattg gagttatgga attgttagat gttttggaga 23400 tttttttagt tatttttttg ttggatttag atataggttt gaataattag gtttaaggag 23460 ttgaattgga gttgtttgtg gttagaggtt tttttttggg aatagtagtg gtggtagtgg 23520 ttgtgttgag tttggtaatt tgtttaagag taggggatgt ttaggttgtg tttgtttttt 23580 ttttatgaat ggtttgtttt gtgttttttt tgtgttaagg gttgttaggt attagatgtt 23640 tattttagga aattagaaaa ataaatagtg taaataaaat aaaaatttta tttaagaaat 23700 ttgagataga tgttgttttt tttattgttt ttttattttt atgttgggtt tggagagagt 23760 gggttagtat gttttttatg gataagaggt tttggggtat ttaatttgga tggaattttt 23820 tttatttttt ttttgtttgg tgttaggggg tagaaggtag gggtggtgtt tatttggttt 23880 agggaggagg atagggtagt ttttgttgtt ggtatttttt gtagagatgt tttagttaga 23940 agtgatttta tttttaggaa tgtgtgtttt gttttttgtt gggtggtttt tttttatttt 24000 ttattgtttt tatagtgggg tgtgttagat ttatgggtag agttttggtt tatttttagt 24060 tttggatagt agaatgtttt agtagtgtat tgatggtgtg tgtgtgggga tgtgtggaat 24120 aggggatagt gattttgtgt gtgttatatg tagtgtggtt tttagttggg tgtgtgaagg 24180 gggtgtttat ggttattgtg gaagtgagtt tagttggggt tggagggttt aggtttattg 24240 tatgttattt agtagttttg ggagtggggt ttattttttt ttttgttttt tttttttttt 24300 ggttttgggt agtttattgg agttgtattt tgggttattt tttttggttt taaggaggtt 24360 gttatttttg ggaggtagat gttggttttt ttatttttgt tttttggaga tttgtgttga 24420 ggtttgtttt tttgtttgga gggattggtt aggaattttt gggttttttt ggtggggttt 24480 ttgttgttta gtagtgagta gagtgagtgg gtattaagag gaggatgttg ggtgaggtta 24540 tggatatggt tggggtaggt tgggggtgtt ggaggtgaat tttgtagttg tgtgattttg 24600 ggtagtttgt ttagttttgg gttttgtttt tttttttatg aaatggggtg ggagtatttg 24660 tttgttgggg ttgtgggttg ggtgaattgg agttaaggta tagtttatag tttgttgtta 24720 gatttttgta agtagaagtg ggtgtttttg tttagtgttt tttggttttt tttttaaggt 24780 ttagttttgt ttttattttt tttatgaagt ttttttggtt attttaggag ttatgattta 24840 tatttttttt ggagttttgt gttatatgta ttttttatgg tgttgttttt tttggaggat 24900 gggtttaatt aaaattgggg tttatttggg ggtttttttt agtattagag aagtttaggt 24960 ttagtagaga tgggtatttt gttaatatta gttttgtgaa ggatatattg tgtttatttt 25020 gttgttagtt gttgagtttg gtgttttgta gttatggaat atgtgtatag gtttgggttg 25080 ttggatatga aggttagatg ggtagtttat tttgtttttg ttttgagttt ttagaaataa 25140 gttggttgta tttattttta tttggttata gtttaggagt ggggttgtgg aatggatgga 25200 aggaaggatg agtgggtggg tgggggggtg ggtgggtggg tggatggatg gatggatgat 25260 gggtggatgg gttgatggat gggtggatta ggtggatagg tgaatggatt ggtgggtggg 25320 tgggtgggtg aagggttgaa taggtgggtt gggtggatgg gtggatggat gtgtggaggg 25380 gtggtggggt ggatggggtt tatgggtgaa tggatggatg gatgggtgaa tggagtaaat 25440 gagtgggtgg atggatggat ggatgttgta agagtttttt tggagggttt tagggaggaa 25500 ttggtatttt tgattagtag ttagtatggt gattagatat agggaggtgt ttgggtttgt 25560 ttgatttttt attttattgt tggtgggatt gggttggtta tgtgtttttg aagttttttg 25620 aagggtggtt gtatggtatt gtttagggga tatttttaga gtgttgtgtt ttatagtaat 25680 agggtggttg tttgtgtttt tagggttgtt ttttttggta gttttttggg tttgtttggt 25740 ttagtatttt agtaaatttt tttgagttag gatttgtttg ttatgagttt ttttaataag 25800 tagttttagg ttaaggtttg tgtgtgggta gagggagtgt atgttgtggg aggttgtatt 25860 aatttgaggt tttgtttttg tttttttttg gggtaaaagg taaaaatagt ttgttttatt 25920 ttatttttaa atttagtttg gttgtattta gttttgggag tgaagggggt tgggttagga 25980 ttgtttgtga gttgtagatt ttggtgtagg gaaattttga tttataagat gggtggatat 26040 ggaggaagga ggagattttg tttagtagag atatgtttgg gtgtagttta gtttggagtt 26100 tgatggatgt gggtttattt gtgtgtaatt tttatttatt gtgtggttat agggaagtga 26160 tattttgtgg agatttagat tttttatttg taaaataggg gtagtagggt ttgggggagg 26220 atgtgtgtga aggtttggtt tagggttttt ttagtagtta gatagtagtg gttgttattt 26280 ttttagtgtt tagggttatt tgggggagta gggtttttgt ttttagatgg gttttgtttt 26340 tggttttgga atttatagta ggagtaaagg tgaggatatt tttggtgtta attatttatt 26400 tggagggaga gtgttagtgg ttttgtgtga tttttgtttt ttgtttttgt ttttaggagg 26460 tatgtggatt tttagtggtt ggttttggag gtttggtgat tttagtggtt taggtaggtg 26520 gtttgttttg ttttggtttt atttagttta tgggtgtgtt tgtgttgggg tttttttatt 26580 ttggtttggg atttgttttt ttatttggtt tttttggatg agtggggtta tttgtttatt 26640 ttttagggag atgtagtttt tgatggtttt ggatttaggt ggtttttagg tttgttgatg 26700 ttgttttgtt ggagatgatt tttgtggggg taggggtagt tatttttagg tttagggagt 26760 aagtttgtgt gtgtgggata gaggagagaa taggagatag atagggttgg atgatttggt 26820 ttgagatgtt gaggggatag atgtgttatg gataggtggt tttggttgtg agttttttgg 26880 tgttggttta gtatttgtgg gttttttgta attttgtagg atggaagatg ttttaggata 26940 gagtagatat gtttggtgtt atttaggagg aaataagtgg gtttttggta gtggttattg 27000 tgttattttt tgtgtttttt ttatgtgttt ggaaattttt tatattaatt agtagggaag 27060 ggaaatagat gtatttatta gagttttggg gttggttgtt taggatatga gttatagttt 27120 ataggtttga agggatttta ttaatattgg gtgtagtttg ggtaagggag tgggatagag 27180 aggttagggt tttgttttta gtttttgttt tttagggttg agtttgtgtg ttattttttt 27240 tttattgggt gtttttgatt ttttttgttt gattttagtg tggttatgtt agtgtttttg 27300 tttttgggag tttatgttgt ttttggttgt tatttttagt ggttaggttg ggataggtgt 27360 ttatttagtg gtttttttat ttggagagga tgatgggtta tagtaatgaa tggatttatt 27420 ttttttagga gatgaggagt tttgagaaga gtagagatgg tgtggttatt tgtgtatatg 27480 tgttgggggt taattgggtg ttagattttt ggttgttatt atggtggtag ataggtaggg 27540 attgtgtttt tatgaattag ttattttaga ggagataaag ttattaaagg atatggattt 27600 ggagttaaat ttatataaat agagtgtttg tggattaggg ttgtttttag aataaggtga 27660 gatagttgtt ttgttaggat aaggtgttta tgggggtaag ggtatgtgtt tatttggagt 27720 tgttattttt atgttttaga ttagttttgt ttaatagaat tttttgtgat ggtgggtttg 27780 ttttatatat ttgtattttg ttattttgta tggtagttgt ttagttgttt gggtttattg 27840 tatatttaaa gtataaatgt ttatgtttat tttatttatt tatttatttg tatagaatta 27900 tttatttatt ttaaatggat ttttatttat atttatgtgt ggttagtggt tatgaaattg 27960 aatagtttta gattatattg gtatttgaga ttttagaatt ttagatttaa agtttgtttt 28020 tgattttgag tttgtttttg tggggatagt atagatgttt tttaagtttg ttttttagag 28080 gtggatgtag tgtttgtgga ttgtgtatta ttaggtttgg atagtggaga gggtggtttt 28140 ttatagggag tgggagtgga ggggatgttg tgtttatatt gagtgtatgt gaggtttttt 28200 gtagtatagg atgggattgt atgtgggaag aggggggtga tgttttggtt ggaggttttt 28260 gggtagttgt atgatttagt gttgtggtta agaggggttt tgtttattgt agttatgttg 28320 ggtattaatt attggatagt ttagttgttg ttgtgttttt ggggagtttt tttttggttt 28380 tgtatttgat ttgttttttt attttttttt tttttattgg ttagtttttg gtggaatggg 28440 tggggagggt tttttagttt ttgtgggggt tgtattttgg gaatttggta ttttgggttg 28500 tatggatata gttttttttg gtggttgttt ttttttgttt agattggttg gttttgtgtt 28560 gttagtattt ggtagttatg attatagttt agtttggaag tttaaggtat aatttgttga 28620 attttaaagt tgtaagttgg tgatttgggt ttgtgtggga ttgtttgttg atatatgggg 28680 tttttttttt gtgggttttt gtgggttttg gtttgagata tttttttttt atttttttgg 28740 tttttttttt tttttttgtt ttttttttgt taagattttg gtttaggtag gagtttattt 28800 ttagatgttt tagtattttt ggttttttta tttgatattt tttagatgat tgtttgttat 28860 tttatttttt tagtttagtt tttttgtaga tttatatttg gttaattttt tatgtttggg 28920 atttttgttt tttttagaag gatgaaggtt ttttttgagg ttgtgtttgg gattgggtta 28980 gggatgatat ttttggtaaa agtttaaatg atattatgat taatgttttg gttagtttat 29040 atattttttt tttttttaaa aaaaaaatgg aatttttaga gttataaaat aaaaatgtaa 29100 agaataaggt aataaaatat ttgtgtattt attattttgt ttaagaagtg agatattgta 29160 ggtgtagttg tagttttggg tgattttttt tattttagtt ttatttttgt tgtggtgttt 29220 gtttttttgg attgggattt ggttttgggt aggtatattt gtgttgggta gtggtgtgtt 29280 tgagaagttt aggttttttt tttttttttt ttgagataga gttttgtttt attgtttagg 29340 ttggagtgta gtggtattat tttggtttat tgtaattttt gttttttggg tttaagtgat 29400 ttttttgttt tagttttttt agtagttagg attataggta tttgttatta tgtttggtta 29460 attttttttg tatttttagt agatataggg ttttattatg ttggttaggt tggttttata 29520 tttttgattt taggtgattt atttgttttg gttttttaaa gtgttgggat tataggtgtg 29580 agttattgta tttggtttgg tttttttttg tatatggtta ttagtattgt gtgattgagt 29640 agtttaggtt tgtttttttt tgaatgttgt tattagtatt atatttttgg tgttttattg 29700 gagttagtgg ttgttttgtt tgtgtttata atgtgatggt gtggagattt atttgtgtag 29760 atttatgaag ttttggttta tttattttgg tagttagtga gtgttttttt gtgtggggag 29820 gtagagtttg tttgttttgt ggtttattgg tgatattgtt gaaggttttt tttgttatta 29880 gtgttgttgg gaatgtgtgt ttttttaggt ggatttggtt gggttgtgga gatgtgtttt 29940 ttagtttttt tagatgttat tattatgttt ttttgagtgg ttttttggta ggttttttta 30000 tgtttgttta ttttttgtgt tttaggtagt tgtttttttg attgagtgtt tagtggattt 30060 ttgttttgtt ttttatggtg tatggagtat tttattttag tggtgtttga gttttttttt 30120 ttttggtttt tagattttgg ttgggatttt tggagttaat ttttttgttt gatattttgt 30180 gttgttaggt tttgtttttt tattttttaa tatttttggg gtgtgtggtt ttttttttag 30240 tgtttttatt attttttttg ttttaggttg aattgtgttt tttataaatt tatgtttatt 30300 aaaaatttta gaatgtgatt tgggagttgg agatggggtt tttgtagatg taagtagtta 30360 aggattttga gatgaggtta ttttggatta gggtgggttt taaatttaat aattggtgtt 30420 tttaaaagaa gtagagaggt tatagatata ttggggagag ttatgtgaag gtaggagtag 30480 atgatggagt gatgtagttt taggttaggg agtgtttggg aagaggtaag gaaggatttt 30540 ttttttattt tattttagag tttttttagg gagtgtggtt ttgttgatat tttgattttg 30600 gatttttggt ttttagtatg ggagagaatt tgtttttatt tttttaagtt ttatagttgt 30660 ggtttattat ggtagttata ggatattgat gtatttttta tttggttgtt gtggatggat 30720 gattttgttt gtaggaagtt ttttttaagt attgtaggtg tttttgtttt tataggggat 30780 gtttgtataa gtaggtgtga aaaaagggtt ttgtgggggt aaggtttggg ttggtgtttg 30840 ttgttttttt ttattttatg ttagttttta tgtttttttt ggtaggagtg tttggtttta 30900 tttggtgaat tagagttaaa tttttttgat aattggttgt tatttattta attgttatta 30960 tttttaggag atagaaaatg ttagaagggt ggggtttgtg tagtgttttt ttgttatttt 31020 tttagggtat tgtgttatgt tgttttaatg tatagagtag ttgtttaaag tgtgttggat 31080 gaataggtgt tttatgttta gttatgtaga taaaagtgtg ttatgtggag ggagttggtt 31140 gtggaagaga ttattagtat tttggttgtt tgaggatttt gtttttgggt ttttgtaggt 31200 atttttagtt tattattttt ttttttattt atagttattt attttttttt tatttttttg 31260 atattagttt tgttatttat ttaggtttgt aagtaggaaa ttttagagtt gattttgatt 31320 tttgtttttt tagtattttt aggttttaat aggttgttaa gattttatta atttgttttt 31380 tgtatattga tttttggata ggttgttttg gttatggtta tgttttggtt gggtttttat 31440 tatttttttt tggattagta ggtgttattt tttttatttt tgttttgttg tggttttttt 31500 ttttttatgg ttaatattta gaggatgatt attatttttt tttttgtgtg ttggggattg 31560 ggtgatagga tttttttatt tgattatttt tattagattt gggttgggtt tttttattta 31620 tagagttttt agtttttgtt tttaaagttt tgagggtgga tttgtgttgt tgtttagttt 31680 ggttttgata ttgtttttta gtttggagtt ttttgttttt gtgtttttgg ttttgagtgt 31740 ttgggttttt tttggatggg ttgttatttg ttttttggaa agtagggttt ttatgttttt 31800 ggatttttta gttgatttag tgattttggg ttattttgtt atattttttt tattagtttg 31860 gttttggtta tttttgtgtt ttttatagtt ttggattaga gttatggtgg gatgtttttt 31920 tggtgtgtgg taggtagtta ggaaatattg ttggattgat tttgatagga gatgtttggg 31980 agaattgttt aaaaaattag tttaaaatgt aaatattggt ttttttttgt gttggttaaa 32040 gagtagtatt tttttgtttg ttttttgggt aagaaattga tggtgaatgt aatgttttta 32100 gggaggagaa gaaggtgata aaaagggttt gtataatggg gtatatgtta ggtatttgtg 32160 attatttaag tttaaattat aatataaatg tgaaattttt tgttttggta gtttttttat 32220 attgtaagtg tttattgtta tatgtggttg ttatattgat tatggtagat atagaatatt 32280 gatattattg tggagagttt tatggggggg tgttggttta gattattttt atgttggatt 32340 tataaattta ttgtttattt agtgaatggt tattgggtat ttattgagta agtaggatga 32400 aagatatttg tttttggggg agttttttgt tggttgtaga gaagtttaaa tttaggggat 32460 ttggggtaaa ttttgtaagg gtttttggtt tttgtatttt tagatttttt ttgttttgta 32520 ggggtagttg ggggtttttt ttaggaatgg agtgttagtt ttagtttttg ttaggttata 32580 gtttagatgg ttggttgagt atgagtatgt gagagtggaa ttgggtttaa ttgggttgtt 32640 tttttttgtt gttttggttt ttttttatgt tgatttggaa ggatttttaa agtaataggt 32700 ttgtttaggt ggtttgtatt agtaaatttt gtagtggttt taagggtaga gatagttgga 32760 ttgtatttat ttaggaatag ttaaagtttg aggtataata aaaagtggag aaagatttta 32820 gagaggaatg tagttggttt tagtttggga atttgttttg tttgggaggt tgtaggtggg 32880 ttaggttggg gttagtttgg agggttttgg ttggttttgt tggtaggtat agtagtaggg 32940 ttagtaggag ggagtttagg atggagtttt tttattttta atttagggaa gtaaatttta 33000 gtggttgagt ttgaggatga gtaggaaatg aatggaaaag tttttttttt tttttttttt 33060 tttttaggta gggttttttt ttgtttttta ggttggagtg tagtggtata attatagttt 33120 attgtagttt taatttgtta ggtttaaggg atttttttgt tttagttttt taagtagttg 33180 ggattatagt tgtgtgttat tatgattggt taatttttaa aagaaatgtt tttaggttag 33240 gtatggtgat ttatgtttgt aattttagta tttttggagt tgaggtggga ggattatttg 33300 agtttaggtg ttttagatta gtttgggtaa tatgatgaga ttttgttttg attaaaaata 33360 taaaaagtta gttgggtgtg gtggtatagt tttgtagttt tagttatttg ggaagttgag 33420 gttgtagtga gttgtgatta tgttattgtt ttttagtttg ggtaaaggga gtaaggtttt 33480 gttttaaaaa aaaaaatttt tttttttttt gaggtggagt tttgttttgt tgtttaggtt 33540 ggagtgtagt ggtatgattt tggtttattg taatttttgt tttttaggtt taagtgattt 33600 ttttgtttta gttttttaag tagttgggat tataggtatg agttattgtg tttggatttt 33660 tttttttttt tttttttttt gtagagatgg gattttttta tgttgtttag gttggttttg 33720 aatttttggt tttaagtgat ttttttattt tggtttttta aagtgttgga attataggtg 33780 tgagttatta tatttagtag gaaaagttat tttttaaagt gagaggttgt gtgtttttta 33840 tagtttggtg tttattagta tggaggattt attggaatgt gtgttaggtg aggggatatg 33900 gaagatggta gtaaatttga gtttagagta ttagaaagta tgtttttagt taaagatgtg 33960 ttttttttat ttttgtgtag tatttttttt tagtgtgtat ttttggagta aggtggggtt 34020 gattttatga agattttttt ttgaaggttt ttgttgttta tattagtgtt atttggattg 34080 tttgtttttt tttttggatg gttggattag ttttagggtt ttttggtttg gtgtggggag 34140 tatagtttat tttggggaat gtttggtatg tgtttttttt ttattgggta ttaggggatg 34200 aagttgtgtt ttgtggaagg ggatagaggt gttggtgttt aggatggtgt atttggggtg 34260 gttgaattgg atttggtttt tattgggttt ttgtggagtt tagattgttg tgagaagggg 34320 tggggaaagg taggtgattt gtatttttta tttttgtttt atatgggaat aggggtttat 34380 tttgtatata tatttagttt ggagtatgaa tttttatgaa gaggaaaatt tttattaggt 34440 tttgatgtta ggattgtttg tgagggttgg gttgtgtttt ggggtaagga taggagtgga 34500 gggggtaatt agggaaggtt ttttaatgga ggaggtattt gatagtattt tgaaaaagaa 34560 gtagttttta ggttaagtta gagattgaag aatgattatt taattttttt tttttttttt 34620 tgagatggaa ttttgtgttg ttgtttaggt tggagtgtag tggtgtgatt taggtttatt 34680 gtaattttta ttttttaggt ttaagtaatt tttttgtttt agttttttga atagttggga 34740 ttataggtat gtgttattat gtttagttaa tttttgtatt tttagtagag atggggtttt 34800 attatgttgg ttaggttggt ttggaatttt tgattttgtg atttatttgt tttggttttt 34860 taaagtgttg ggattatagg tatgagttat tgtatttggt tatgattatt taattttttt 34920 ttataagatg ttttttggtt gatgtaaagt aggttgagtg agtgtgatat tttttttttg 34980 tttgtgggtt ttggtttttt tagagtttgg ttagtgttat tggagataaa gtggtttttg 35040 tttttttttt ttgttttgtt aggtttagtt tgtgttgttg agttttattt tgtaattaag 35100 aggagttgtg aattagtgat gttgatgttg tagaaaagtg gttaggggtt tatggggggt 35160 gaaggatagg gatgttgttt tgagaattgt ttggaagggg tttttgggta atagtgttta 35220 ttttagggtg tgggtaggtt ggggtggttg ggagttgggt ttataggttg gtataattag 35280 agttttttaa agttgtgggt ttgagggttt tgtttttttg ggatagtaat ttttggttta 35340 atttgggaaa aggtgggtta aattaagttt ggttttttta ttgtaggatt atttagtgtg 35400 tttagtatgt aaatgtgttt ttgaatttaa gataggatta tagaaatttt tttagtgttt 35460 ttttggaggg agggattgtg ggggatttat tgtaggggtt tgggtttgta ttggtttggt 35520 gaagtgtttt tttagtgttt atattatgtg tggtgagagg ttggtttttg ttttttttat 35580 tttttgttgg ttttatttta ttatttttgt atttgttttt tagttggttt atgattaatt 35640 tttgtttttt tagagttaat tggtgttgtt aggtttttta ttttaagtga ttttttgttt 35700 gggttaaaat gtttggattt ttaggtatgg aggggagatg gattttaggt taaattatgt 35760 tgggtaaaat tgagggttaa ggttgtgttt agtaagtgtt ttagttttgg ttgttaaatt 35820 tatagtgtgt atagtgtgta ggaggtggtt gggtgaatga atttagttat agtttggttt 35880 tttatttggg gttgttttta agtttttatt gttagttagg ttgggttaga gttttgtggg 35940 gtttttttgg gtttttttgt tttatagtag gagtttgtat ggagagtttt gagtgaggtt 36000 aatgggtttt tttttttttt tttttttttt tttttaattt gagatagggt tttatttttt 36060 ttatttagtt agggtgtagt agtgtaatta tagtttatag tagttttgaa tttttggttt 36120 taagtaattt ttttgttgta gttttttaaa gtgttgagat tataggtatg tgttattttg 36180 tttagttggg gtttttgttt tttatttttt tttttgtttt taaatttaat ataaagaaag 36240 atattatatt tataattaga aaaattaata aggaatatta ttttaaaatt ggaaaaggga 36300 ttaaagaaat aaattaagaa atttttgtga tttttgttta ttggagttag tggttgttag 36360 tggttggttt aatataatgt tttaggaaga aatagaataa tagaaagtaa ttttagtgag 36420 ttgagttttg gttttgtttg tggtgttgta ttagtttttt gtagttgttg taatgagtgg 36480 ttataagttg gttgggttat aataatgttt agttattttt ttatagtttt gtaggttata 36540 tatttgagat tagggttatt aggttgaaat tagggtgttt attgggtata gttttttgga 36600 ggttttaggg taggggtttt tagttttgtg tgttttatta ggaattggtt tgtatagtag 36660 gaggtgagtg attggtaagt gagtgaagtt ttatttgtat ttatagttat tttttattgt 36720 ttgtattatt gtttaagttt tgttttttgt ttgattagtt atggtattgg atttttatag 36780 gagagtgaat tgtattgtga atggtatatg tgagggattt aggttgtgtg ttttttatga 36840 gaatttgatg tttgatgatt tgttattgtt ttttattatt attagatggg attgtttggt 36900 tgtaggaaaa taagtttagg gttttaattg attttatatt atggtgagtt gtataattat 36960 tttattatat attataataa taatagaaat aaagtgtata attaatataa tgtgtttgtg 37020 gttgggtgta gtggtttata tttgtaattt tagagtgaaa ttttgtttta aaaaataaaa 37080 aataaaggtt aggtatagtg gtttatgttt gtaattttag tattttggga ggttaaggtt 37140 ggtggattat gaggttagga gtttaagatt agtttggtta atatggtgaa attttgtttt 37200 tattaaaaat ataaaaatta gttggatatg gtggtaggtg tttgtagttt tagttttttg 37260 ggaggttgag gtagaagaat tgtttgaatt taggtggtgg aggttgtagt gaattgagat 37320 agtgttattg tattttagtt tgggtggtag agtgagattt tgttttaata aaataaaata 37380 aaataaaata ataaatataa tatatttgaa ttattttaaa attatttttt tattttttgg 37440 tttgtggaaa aattgttttt tttgaaattg attttaggtg ttaaaaaggt tgggggttat 37500 tgtttttatt gtttgttttt ttgagttttt ggtggttgtg ggtgtttttt ggtttgtggt 37560 tgtatggttt ttatttttaa tattagtatt tatagatttt tttgggtttt atttttattt 37620 ggttattttt gtttgtgtta aatttttttt tgtttttgtt ttgtatgagt attgagattg 37680 tttttaggga ttatttagat tatttagggt gtttttgtta tagtaagatt tgtaattgaa 37740 ttatagatgt aaaaattttt gttttaaata aggttttatt tgtaggttta gggattagga 37800 tatgttattt ttggggttat tatttagttt ttttttgtga ttatgatttt tttttttttt 37860 tttagttttt tattttggtt gagatgttgt ttttattttt tttattgttt ggttgtttgt 37920 ggggttgttt tttaggtttt ttgggaggag gtggttgttt gatgtttttt agaaggttgg 37980 gaatggtttt ttttattttt taggaagatg ttttttttgt taaggagatt gtatttgggg 38040 ttttatttta ggtagagagt ggatgggatt gtggtttgaa gtggtatttt agggtttttg 38100 gttttgttat ttagttgagg gttgtgtatg ggttttattt ggttataggt aatttatttg 38160 gttttgtggg gtagggattg taaatttaga ggtttgtggg gtgtgttgag gtagaggggt 38220 gtaaatattg taaatttgtt gggggttttg gggagtagta tagattgaaa agtgttttgt 38280 ttgaagagta gaattgtttt atattagttt tgtgtggtta ggtaggaagg tttttgtggt 38340 gtggttatgt gttttttttt ttttaataga agttgatagt ttggagtttt tagagagatt 38400 gtttgagttt ttagttttgg tataaatata tatttttttt aaataggttt gggttaatag 38460 aattagtttt tgtgttttgg gtttgaatga atttttgagg tgaagtttaa agatagagag 38520 gatgtttttg atttttattt tagggattta tattgtaaat ttttatttgt tttgttgagt 38580 ttttggtttt agtatggatt ttgattatgt gttggtgggg attttttagg taagtaagta 38640 gtttttgagg attttggatg aatagtgggg aatagtattg attttttagt ggggttttga 38700 gtttttggag aggaagattt gttttttttt aggggatggt tagagattta ttgatttatg 38760 tgtgtgtggt aggaattttt taggaagttt ttgttttgtt tgtttttttt gtttgggtgg 38820 ggatggtaat tgtttttgtt attgtagatt aatgggatgg aggggggtga ttttttaggg 38880 ttttttttgg gtaggtgttt tggaattttt ttttagtatg ttggtttggg gtatggttgt 38940 tttttttgtt tagttatgtt ggggtatagg gtgaagaagg gttggggtta gtttaggata 39000 gaggaaggtg aggtaggtat gtaggaattg ggttttttaa atttttaagt ttaaggaaat 39060 tgtagtattg tgggataggg aaaatgaaag attttggaag ttgttaggaa tttgattttg 39120 tgagttggtt tttaagagtt taagttaagt atttttaagt ggatattaaa aaggagtagt 39180 aagttttggg gtggtggggg ttggaggagg tggagagagg aggttgttgg aagttgtatt 39240 tgggattttt gtagttattg attagattgg gtggttggga ttttgggatt tttgtaggta 39300 gatttggtgg tttgttggat tttttggggt ttattttggg tttttttttt tgttttttat 39360 ttttggattt tttttttttg tttttttttt ttttttgttt tgaagagata atgttatttt 39420 agtttggagt ataaatatat gattagtata tggaaatgtg gtaatttgga tgtatttgtg 39480 attgtaatag attgaagaaa ttagattaga taaagagtgt ttttagagga ggaggaggag 39540 gaggaggagg ttgagagagg gagggtgatg ggggtgagaa aggggaggtt gtttttgagt 39600 gggatgttgg gatttttgtt gttgttaaat atatttgtag gaatggagag ggattggatt 39660 ttaggtatgt agatagtttt ttttttattg gttgtttttt attgttttgg atttggggtt 39720 ttatttatgt ttgggggaat aagtatgtaa agggtgtttt tgtttatttt ttatagaaat 39780 attttttttt tttttgatgg ttttaagttt gtgggatgaa ttttgtttta gaagttaagt 39840 ttttttgagt ttggttttta tttaaatttg gttttttttt tttttggtta tttttttttt 39900 attttttagt gtgttatttt tgtatgttat ggttattgtt aatgttgagg ttgttggtgt 39960 tgaaattttg ggagggtgtg ggggatttgt ttttttggtt tgggtttggg gtggtggtgt 40020 ttggatttgg ttggtggttg gtttgtttat tgtgtggttt gttttttgtt tttagttaaa 40080 gtttgttttt aaggttgttt tggtttttta tttaaaatag tatttttgtg tttttttggt 40140 agttgattat agagggggaa gtttttggtg tttagaggag tttggtgtgt gtgtgtatgt 40200 gtgtgtgtat gtgtgtgtgt gtgtttattt atgttggtag tttttttgtt gtaggtatag 40260 atttattagg gtgtgaatag gtaaatgaag agaaaggggg tttttttgtt tttagtttat 40320 tttagttttt taggtttttt tttttaggtt tagttttttt ggttttttta tttatatgtg 40380 gtgttgtggt tgttatttta tgtggttagt gttgttattg gtaattagta gtgatgatag 40440 tttttgttgt ttatgttgtt ttttgagttt agtgttggga gatatggggt ggttgagtta 40500 agttttaggt tttgggtatt ttgaagtgat ttatgggtta tggagtggga ggttgttaag 40560 agtgttaatt tttatgtgtt ttgggttttg gtttgttggt tgttattatg tgtgtgttgg 40620 ggggtttttg agaggtttga gagagggagg tttattttgg tggttttttt ttaggatgtg 40680 tggttttttt tattattgtt tttagggtta tatttttttt tttttttttt tttgagatgg 40740 agtttggttt tgttgtttag gttggagtgt agtggtgtga ttttagttta ttgtaagttt 40800 tgttttttta gtttatgtta tttttttgtt ttagtttttt aagtagttgg gattataggt 40860 gtttgttata tttttttgta tttttagtag agatggggtt ttattgtgtt aattaggatg 40920 gttttgattt tttgattttg tgatttgttt gttttagttt tttaaagtgt tgggattata 40980 ggtgtgagtt atggtgtttg gttttagggt tatattttga ttgttatgtt gggattggtg 41040 gagtgggtgt gtgttgtgtt gttgagtata tttagttggg tatagtaggt ggattttagg 41100 agggggttag gggagatggt agaaggtttg ggtggtagtg aaattgtatt ttatttgttt 41160 gagtttgggg gtttaggttt gttgggatgg gtgggtgtgg agtttagtgt tttgtttttt 41220 gtttagtagg agttgtaggg tagggagtgt tgagagggat ttttgttagg tttgtatagt 41280 ggagttgttt ttggagtgat tattttatta ggtagtttgg gtagattata gtgggttttt 41340 tgttttttgg gttattagtt ttaggaggat gttattttat ttgtttggtt ggtaggggtt 41400 ttggggagtt ttgggtttgg tttttatttt atagatgatt tagttgaggt ttagatgggt 41460 gattagtagg ggatttgaga gttgagtaga gaggtgtggg tttgggggtg gtgttttttg 41520 gggagttgga agtgatggta tttttttagg tttataaaat atgggttttt tatgaattga 41580 ataaaatatt ttttgaaagt agttagtgtt gtgttttaga gattattttg atttttgttg 41640 tttttggttg aggatagtat agttagggat gaagtgggga tttttttttg ggttgtgttt 41700 tgatgaaaga tgttttttat aaaattttat ttggatgtgt ttttatgtaa gaaaatgtat 41760 atttttagaa atttagttgt aaattggttg ttttttgaat gaatatgata gttttggagt 41820 tgtttttttt aatgaggttt ttgttttggg taaattttag tgttggtttt taattgttat 41880 tgaatttttg tatagttttt ggggaagtga tttttttttt gtttttgttg ggtggttttg 41940 agtaagttat ttggtagttt tgggttgtag ttttgttatt tgtaaggtga ggggtgggag 42000 tggtatggtt tttaggtagt gtttttattt tttgtgggtt tttgtgtgtg ttttgagttt 42060 tgtgggtgtt ttttttttta ttgaggggtt tttttttttt gtagggtatg gtttatgttg 42120 tgttgttagg ttgtaagtta ttgtgagagt tgttttgatt tttaagtatg ttttggtttg 42180 aggaggagtt atggggagga tgttgtgttt gtgtgataga ggtttgtttg gtagatgttg 42240 gtttgttgat ttttagatgt ggttgtgggt gttttatgtt ttattgggtt ggtgtgtgag 42300 gtgtgtttag tttaggttgt tttatagttg tttaggaagg gtttgtggga gggggtggtt 42360 ttattttggt gagtttatgg tggtttgtta gttttaggga aggtttagga gttttaagat 42420 ttgttttttt gttttttttt tggtagtgtt tggttttggt ttggtttgtg aatgggggtt 42480 tgggtatttt tttgtttttt ttgggggttg tggttttttt ttgggaaggt gttggagggt 42540 ttgttagtag ggttggtatg agttatggag tggtgattgg ttgttgaggt atggaaggtt 42600 atttttttta gttaagggtt ggagtttttt ttttgttttg gaatggtttt gtggttttta 42660 taaattaagt agttttattt tgttttaaga gtttgtattt tagtagggag agagttttta 42720 agaagggaat tttttattgg ggagttttgt tgggttggga ggttaggaat aggttatgag 42780 ggagggttgt aggtagggga agtggttgtt tgtgtatggt tatgaatgta ggtttggggt 42840 tttggagggg gtttggttat gttgttgttg gatgtttgtt tttattaggg tttatttgat 42900 gtagtatggt atagggtaaa gtttagtttt ttttatgggg tttttgggtt attagtgggt 42960 ggggaattga ggttttttgg agggtggtgt tttagttttt attttttttt tttgtttttt 43020 gttgtgttgt ttttgatggt ttttgttatt ttttgggagt ttttattttt ggatgtttgg 43080 tgtttgtttg gttttaattt ttttagtttt gtttttttat ttttgaggtg agaggtttgg 43140 tttgatgtgt tttgtatttg ttttttgttt agttttgtgg gaattttggt ttttgtagtg 43200 gttttttggg gttgttatta ttaagtgtta taaattgggt ggtttaaaat attagatatt 43260 tttttttttg ttgttttgga ggttagaagt ttgaaattat ggtattagta ggtttggttt 43320 tttttggagg ttttgagggg gagtttgttt tttgtttttg gtagtttttg gtggtttttg 43380 aaatttttgg tgttttttgg tttgtggtta tattatttga tttttgtttt tgttgttatg 43440 gggttttttt ttgtgtttta aatttttttt tgtttgtttt ttatatggat agtttttttt 43500 ggatttaggg tttattgggt aatttaaaat ggttttattt taagattttt aattttataa 43560 tgtttgtaaa gatttttttt ttaaataggt tatgtttata ggttttgggg tggatgtaaa 43620 ttttaggggt tattttttat ttttttgttg tttttgtgtg tttggatgta tagtatggtt 43680 ttatgtttta gattttttgt tggatttttt tggttttttg gggtggtttt tggttttttt 43740 tatttgtttt tgtgtttttg gtgaggtgtt ggggttgggt ttagtttttg taggaatttt 43800 ggggatagta tggagttggt aattttttat taggtgtttt tttatttgtt tagagtttat 43860 ggttgtgagg ggtttttttt tgtggttttg atttgtaatt ttttagtggt tagtgatgtt 43920 gagtattttt ttgtgtttat tgtttatttg tatatatttt tgtagaaatg tttgtttaag 43980 ttttttattt gtgtttgatt tggatgattg ttgttgttga gtgttaggag atttgtagat 44040 taatatttag atattaattt tatatttgat ttatgatttg ttgttatttt atggattgtt 44100 ttttttttat gttgttagtg ttttttgata tgtaattttt tttttttttt ttgagatgga 44160 gtttgatttt gttgtttagg ttggagtgta gtggtatgat tttggtttat tgtaattttt 44220 gtttttttgg ttttagtgat ttttttgttt tagttttttg agtagttggg attataggta 44280 tttgttatta tatttagtta atttttgtat ttttagtaga gatggggttt tattgtgttg 44340 attaagttgg ttttgaattt ttgattttaa gtaatttatt tgttttggtt ttttaaagtg 44400 ttggagttat aggtgtgagt tattgtattt aggttgatat gtaaatattt taaattttta 44460 tgatgtttta ttttatttat ttgttttttt gttgtttgtg tttttggtgt tatatttaag 44520 aaattattgt taaatgtaat gttaggaagt tttttttttg tgtttttttt taagagtttt 44580 gtggttttag tttttgagtt taggtttttg atgtaagttg agttgatttt tgtatgtggt 44640 gtaagggttg gtttagtttt atgttttggg tttttgattt attttttttt tttttttatg 44700 tttagttggt tttgttgggt ggtggggagg agtggggaag ttttgggttg ggtttgtatt 44760 tgattatttt tttttaggtt agttagggag ttttagtttt tgtttaggat ttggttggat 44820 gtgtttttta ttgggaaagt ttgggttgtt tttttaggtt gatggtaggg ttagtttggg 44880 gtgttttgag gtttgttttg tggatatgtt ttttgtttta ggtggtgtgg ttgtttggtt 44940 tgtgtgtgag attagttgtt tgtgttttag gttatggagg ttgagtgttt ttagtttgtt 45000 tttttgtttg gttttttttt tggggaagtt tttgtagttt attttttgtt tttgtttttg 45060 ttatttgtgt ttttgtttgt tttttgtttg gaggtggtta tttttggggt tattttttat 45120 gatttggata taagttttta ttttgaagtt attatttaaa tttttgtgtt ttaaattttt 45180 tttatttatt atatgggttt ttattgtgat taatttagta gttgatgaag ttttttttgg 45240 ggttttttta gtaatgggga gttggttttt ttggaggttt ggtttttttt taagtggaag 45300 tggggtgtga gggtgttagt ttttttttgt tgtttggtgt tttaggttgg tttgttattt 45360 ttggaagtat ttgttatttt tatatagtat tttatattta tttttttgtt ttttattttt 45420 ttttttaagg ggttattttt gttttttttt ttatttaatt ttatttatgt ggtttgttta 45480 gtaatttttg atttttaata tgataaaata aatttttttt gttggttatt tatttattta 45540 tttagtattg ggtgtttttt gtggatttgg tgttggggtt ttgtggagga taaagttaga 45600 tatagttttt gtttttatgg gattgtataa gtgtaagatt atattagtaa atgtgaaata 45660 taggaagtga taggtgtgat aaaggggatt agtggtagga tagaatttgt ggtttgtagg 45720 attaggttag gagggttgtt ttggggggat atttttgggt tgagtgtaga aggatgaggg 45780 gagtaaatta ggtttaaatt tagtaggtag aggtgattgt tgtaggtaat tggtaatgtg 45840 tttaaaggtt ttggggtgtg gggggttgag gttggtagta tggtaggaag taagattggg 45900 gttgaaagag attgattgtt atgttgtgaa atatatattt ggtttttatt tttatttttt 45960 ggtatataat ttttaaaatt tttggaattt ttaaagtgat gtttttttgg atgtttatga 46020 ttgatagatt agttggtagt tttaggatgg tttttaggga agattaggta gaattataag 46080 gtttagtatt attttgtaat ttttaggtag gggagagggg ttgaaggtta agtagattat 46140 tagtggttaa tgattgaatt aattatgttt ttgtaatgag gtttttgtga atatttagaa 46200 ggatggggtt ttgggagttt ttggatggat gagtatgtgg aggtttttgg agggtggagt 46260 gtttggggag tatatggaag ttttgtgttt tttttttata ttttgtttta tatatttttt 46320 tttttgtatt ttttgtaata ttttttataa taaattagta aattttatga gttttaggaa 46380 tatgtgtaaa agaaaaaaaa aagaataaat tatagttgtt gtagtaagtt aattttatta 46440 gtattggttt ttatttgttg attttatttt tggtaatgtt tttttttttt gggtttttgg 46500 gatttttttg gttttattat tttttttgta gtggttttgt tggttgttgt ttttaggtta 46560 gtttattttt atttggtttg tttttattag gggttgaggt ttttttgttt attttagttt 46620 tttggtttgt tttttgtttt gggtattttt ttattttgaa tggttagagt ttttgaagtt 46680 gtttgttgtg tgtttttgtt tggttttatg tattttgtat ggtgtttttt agggtttttt 46740 attggtaagg gtattggtat agattttggg gttgttttgg tttaagttta ttttgatttg 46800 gagtttgagg gtttttgagg gggttttgaa ggttagggta ggtaaggttg gtatgttttg 46860 ggtagtgggg gttgggtatg ggaggggatt gtgggtgggg agattttttt taattagtgg 46920 tttatgtttg gagattgatt tgggttttag gttatgtttt gaaattggga tagagagtgg 46980 tgtagatttt agtttggaga ttttttttgt ttgtggatgt ttttatattt ttatttgtgg 47040 agttattttt tttttttttt ttttaaatgg ggaaattttg atttgaatat tgaataaata 47100 atatattttt gaaattagtg aagaggtatt ggttttgaaa ttttgttatg aaagtttgaa 47160 aatgtttttt ggattgattt gttggaatag atgggtgtga tggggttgtg gggttttagg 47220 tggtaggagg tgtttttgtg tttagggtat tttgatgttt agagtttttt tgtgtttagt 47280 gtgtttttgt atttagggta tttttatgtt tagggtgttt ttgtgtttag tgtgtttttg 47340 tatttagggt atttttatgt ttagggtttt tttgtgttta gggtgttttt gtatttagag 47400 tatttttatg tttagggtgt ttttgtattt agggtgtttt tgtttttagg gtgttttgtg 47460 tttagggtgt ttttgtgttt agtgtgtttt tgtatttagg gtgtttttat gtttagggtg 47520 tttttatgtt taggtattgt ttttttttat ttttttaatt tttttttatt aataggtgtt 47580 agttgtgaaa tgtttgttgt gtgtgttttt tggttgagtt tattttgtgt ttttaagttt 47640 ttgttagata taggtaggtt gttttagttt ttttggtaaa tgttttgttg ttgttgtttg 47700 atatggggtt ttattttgtt atttaggttg gagtgtagtg gtgttatttt gttttattgt 47760 aatttttgtt ttttaggttt aagtgatttt tttgttttag ttttttaaat agttgggatg 47820 ataggtgttt gttattatgt ttggttaatt tttgtatttt tagtagagat ggggttttat 47880 tatgttggtt aggttggttt tgattttttg attttaagtg atttatttag tttggttttt 47940 taaagtgttg ggattatagg tatgagttat tgtgtttggt ttgtttggtg aatgtttatt 48000 gaggtttatt atgtgtagtt ttttttttag gtgtttggtt tgtaatgagg agtaataaag 48060 atatagttgt tggttgtttg ttatttaata gttggaattg agaggtagtt tataaatgag 48120 taaatttata ggtggtttta gatgaggatt gtgaagaagt taagaatagg ttgttggggg 48180 tgtatatttg tgtgtgtggt gaggggatta atggaagttt tttttgagtg gtgatattga 48240 gttgaagttg taatgattag aaggatttag ttaggttaaa atttaaggga agagtaattt 48300 ggtaaaggaa atagtaggtg tgaaggtttg aggttggagt ttggggaagg tgggagtggt 48360 tggagtgtgt ttttagagat gggttatggt gatattaatg tgataggtag ggttaggttg 48420 tgttgggttt tggaggtttt ggtgagggtt tgattttatt tttattatgg tgggatttta 48480 gtgttttgtg gttgttgaga atggttaggg gtaggtaggg aggtttgtta gggaggaggt 48540 tgttgtaggt tttgtagttg gagagggagg attaggattt ttttagagag gaagttggag 48600 agggaggatt tttttgattg ttggatggat ttatttgttt ggttgttttt gttagtattt 48660 agtagaggtt attggatgtt gataggtggt tggttttgtt tagttttgta ttgttttgtg 48720 ttgttttggt ggttgttggt tttaggagga gtgtttttgg tgtttgagtt tagtggtttt 48780 ggttgtggtt tggtatattt ggttgtgggt gaggttaagg tggtttggat tttgggaagg 48840 ttgggtattt ggtagtttta aggtaggagt tggggtgttg gaggaggaag tatgtttatt 48900 ttttgttttt ttttgttttg tgggatgttg agtttttggg tagggatatg gtgagttttg 48960 gtgtgatgta tttaatattt gttggtgttt ttatttttaa gtaggaattt tggtgtttgg 49020 tgtttgagga ttgttgttta ttgttttatt attttttagg ttttttttta gtttttgatt 49080 tggggtaagg tttagatatt tagaatattt ttggttggtt tttggagttg gggtgaggta 49140 gaattttttt tttatattta tagtattagt taaggttttg gggtttggat attatttttg 49200 ggaggggtga gtaggataag tgaggttttt agatttgggg tggttttgga ttggttaggt 49260 aggtgggtgg gggttgtagt ttatgttttt gttttaggta atatagttga gttgtagttt 49320 ttgttttatt tttagttggg gttttttgtg tttatttttt gttttttttt ttttttttgg 49380 aatggggggt ggatatttta agattagttt tttagttatt ttttttgttt tttgtttttt 49440 tttttttggg atagattttt gtgattgttg ggtgtttttg atgttttgtt ttttttgtgt 49500 tttgtgttgt gggtgagaga gggttttggg gggatttttt ttttttggag tatttgttgt 49560 tttgggtgtt tttgggggtg ggtttttatt ttatattgtg gagttggtgt aggaaggaag 49620 gtgttgggag ttagttttaa tttatgtgtt ggttgtggtt tttaaggtgt ggatggtagg 49680 aggtggtgag atagggattt attgattatg ggattgatat ttttttatgt tgatgtgggt 49740 tttgagttat aattttatta gtttttgagt tttggtgttg tttttggtga tggtgtggat 49800 ttagttaggt ttttgggtag ttttttttgg attttttttt tgtttttttt tgggtagtgt 49860 ttttgtttat ttggaaagga tgggtaggat ttggagataa tagggattta aagaagttgg 49920 gagtgggggt atttgtgtag tttattttgt agaatagata atttggttaa agtttaaagt 49980 ttgttgttag gagttttgtt tgttttttag agagtatatg gtttgattat tatggggatt 50040 gggggagagg tataggtatg tttgtttggt agtagaaggg aattttgggt ttgggttttt 50100 ttattttgtg gtgttgtttt tttttagagt tgtattgttt tttttattgt ttttgtttgg 50160 ttttagtgtt tatgtggttt gtggttttta gtttgggttt ggttttttgt aatttatttt 50220 gtttagtttt atatagtttg tttttttagt tgggaattgg agtttatttg gagttttagg 50280 tagtagattt gatgtagtga tgtagggttg ttagttatgt tagtaggttt tgttgtttat 50340 agagggatgg gtattgttgt tgataataat taaagaatta tggttttagg ttgggtatag 50400 tggtttatat ttgtaatttt agaattttgg gaggttgagg taggagaatt aattgaattt 50460 aggagtttta gattaggttg ggtaatatag taaggttttg tttttataaa aaataaaaaa 50520 taataataat aataaaaatt atagttttag aatgattgat tttagtatgt ttataaagtt 50580 aagggttttt agtgttttgg gtttatgtta ttgtgttaga gggagagagg aagaggttgg 50640 ggtgatgggt attggggttt atgttttttt tggaatgggt ggttttggat tgtgtttgtg 50700 tgatatgttt gttgagtggg ggtggtgttt attgaggatt ggatgttgag gtgtgggtgg 50760 ggggaggtta tgaagtattg ggtatttttt gtgtattagt gttttgagat tgtagagagg 50820 ggatttgttt agtttgggta gggaggtggg tggtagtgag gaaggggaga ggaatttggg 50880 tgtagaaagt ttttttttta gtaggtggtg ttgtaagttt ttgagagttt agtttttgtg 50940 gggtttgtat ttttattgaa tttgtgggta gaggttgttt gggtgtagtt tttgttaatt 51000 gtgattgttt attgtgggtg aggggaagtg gagtgtagag aatgtattgg agggtagatg 51060 attagttttt gtataggtat gggggtgttt ttttttttgt ataggtatgg ggggtttgag 51120 tttttggggt ttttgtttta attgggtggg gaaagggagg gttggaagtt gagttagggg 51180 gaaagggggt ggttttttgt tatttttttt attttatttt ttttattttt ggttgatagg 51240 ttttaatttt ttttatattt ttttaatttt ttgttgtaaa attttttaaa tatagaaaag 51300 atgaaagagg gttgagtgtg gtggtttatg attgtaattt tagtattttg ggaggttgag 51360 gtaggaggat tatttgagtt taggagttta agattagttt gggtaatata gtgagatttt 51420 atttttataa aggatataaa aaattagtta ggtatggtgg tgtaggtttg gagttttagt 51480 tatttggaag gttgaggtga gaggattgtt tgaatttggg aggttgaggt tgtagtgagt 51540 tgggattgtg ttaatgtatt ttagtttggg tgatagaata aaattttgtt ttaaaaataa 51600 aataaaataa aattataaaa aagaaattat gaaagatttt aaagtaaata tttatgtatt 51660 tattatttag attttatagt aattattttg ttgtttgttt tattataaat ttttttggtt 51720 attagtattt atgttggttt tgatgtattt aaaataagtt gtagaaatta gtatataata 51780 ttttgttaat attttagttt gtattttatt aattagagtt tggtatttgt ttgtgattat 51840 ttttgttttt ttttgaagta aaatgtatat attttgagat gtataggtgt gaaatgtttt 51900 gttttttgaa ttttaataaa ggtatttatg tgtattttag tttgattaga atatagaata 51960 ttattattat tttagtaagt tttttatgtt tttttaggtg tattatagtt tttatttttt 52020 ttagggtaat tataattgtg tttttttttt attatgaaat aattttgtta gtttgagtgt 52080 tttttagagt tatttatgtt gttgtaggtg ttagtgattt gttttgtttt attgttgagt 52140 aatgtttatt gtgtgaatat tttgtgggtt tttagttatt tttttgttga aagatttttg 52200 gttgttttta tttggaggtt tttatgagta aatttgttat gttggttttt tttgtataag 52260 tttttttgtg tatatgggtg tttatttatt ttgtagaaat atttagagta ggtatagggt 52320 aggtatatat ttagttttat aagaaattgt tagatttttt tttaaagtgg tttttttatt 52380 ttatattttt attagtaatg gatatgagtt ttagttgttt tatattttgg ttaatatttg 52440 gtgttgttat tttgtgaaat tttagttatt ttggtgggtg tgtagtggta ttattttatt 52500 atggttttaa tttgttttgg tttgatgatt aatgtggttg agtatatttt tatgattggt 52560 tttttatata tttttttttt gtgaaatgtt tttttaaatt tgttgtttat tttaaaattg 52620 ggttgtttga tttttttttt tggatattga ttttttgtta gatatgtgtt ttataaatat 52680 tttattttag tttgtggttt gtttgtttat tttttttttt tttttaagaa taaggttttg 52740 ttgtattgtt taagtaggtt tgaaattttt gggtttaagt tgtttttttg tttttgtttt 52800 tttaagagtt ggttttatag gtatgagtta ttatgtttgg tttgtttatt tttttagtgg 52860 tattttttaa taagtaaaag tgtgttattt taatttttat gaagtttaat ttaataaatt 52920 tttttttttg tggttttttt tttgtgtttt ttgtaagaaa tttttgttta ttttgttaaa 52980 ttgtaaagat atttatgttt ttttttagaa ggtttagagt tatatagttt ttatgaatta 53040 atttttgtat atggtgtgag gtagagggtt agggtttatt ttgttgttgt tttatgtgtt 53100 tatttagttg ttttaaattt tatttttttt taaagttttt attttgtatt tttttggtga 53160 tttatgaggt tgtataattt tttaagattt ttgttggtta tttatgtatt tttttttgta 53220 aaattatttg tttatgtttt attttttttt aaaattatgt tgttttaaga ttgagtgatt 53280 tttgaagttt ttattttata atgtttgaaa gaatgaatat tttgtttttt agttataggt 53340 ttttgttttt tgttttgtag ttgtatagtg gggtaagatt tgggttttgt tttgttgttg 53400 ttttgttgtt tttttatttg attgtttttt tatgggtttt atttaaaaaa aaaattggtt 53460 gggtatagtg gtttatgttt gtaattttag tattttggga ggttgaggtg ggtagattat 53520 gaggttagga gattaagatt attttggtta atatggtgaa attttatttt tattaaaaat 53580 ataaaaaatt agttgggtgt ggtggtgggt gtttgtagtt ttagataatt gggaggttga 53640 ggtaggaaaa tggtgtgaat ttgggaggtg gagtttgtag tgagttgaga ttgtattatt 53700 gtattttagt ttaggtgata gagtaagatt ttgttttaaa aaaaaaaaaa aaaaaaaatg 53760 ttgttttata tgttttttat atattttgga tataagtttt ttattagata tatgtattat 53820 aagttttttt ttttatattg tttttttttt tttggttttt ttaatgatgt tatttaatga 53880 gtaagagtat tttgttttta taaagtttaa tttattaatt ttttttagtt ttgatttatg 53940 atttttgtga tttatggagg aaatttttgt ttatattaag gttaaaagaa gtttttttat 54000 tttttagaaa ttttatagtt gtatatttta tgattttttt tattttttaa ttttttaaat 54060 ttttatattt tttaatttat tatagttgtt aggatgttgt atgatttatt ttaaattagt 54120 ttttgtattt ggtttgaggt tagggttaat ttttgttttt ttatatttat atttagtttt 54180 agtattgttt gttgaaaaga tatattttat tttattgaat tatttgatat ttttgttaaa 54240 aattattgat tgtatatgtg gttttatatt agtatatgta tgtatatata tgtaggtttt 54300 gtgttgattg tatgtgtggt tttatattag tatatgtatg tatatatata ttggttttat 54360 gttgattgta tatgtggttt tgtattagta tatatatatt agttttatat tgattgtata 54420 tgtggttttg tattagtata tgtatatata tatatgtagg ttttatgttg attgtatatg 54480 tggttttata ttagtatatg tatatttata tatgtaggtt ttgtgttgat tgtatatgtg 54540 gttttgtatt agtatatgta tatatatata tataggtttt gtgttgattg tatatgtggt 54600 tttgtattag tatatgtata tatatatatg taggttttat gttgattgta tatgtggttt 54660 tgtattagta tatgtatata tatatatata ggttttgtgt tgattgtata tgtggttttg 54720 tattagtata tgtatatata tatatgtagg ttttatgttg attgtatatg tggttttgta 54780 ttagtatatg tatatatata tatgtaggtt ttatgttgat tgtatatgta gttttatatt 54840 agtatatgta tatatatata tgtaggtttt atgttgattg tatatgtagt tttatattag 54900 tatatgtata tatatatatg taggttttat gttgattgta tatgtggttt tgtattagta 54960 tatgtatata tatatatgta ggttttatgt tgattgtata tgtggttttg tattagtata 55020 tgtatatata tatatgtagg ttttatgttg attgtatatg tggttttgta ttagtatatg 55080 tatatatata tatgtaggtt ttatgttgat tgtatatgtg gttttgtatt agtatatgta 55140 tatatatata tgtaggtttt atgttgattg tatatatata tgtggttttg tattagtata 55200 tgtatatata tatatgtagg ttttgtgttg attgtatatg tggttttgta ttagtatatg 55260 tatatatata tatgtaggtt ttatgttgat tgtatatgtg gttttatatt agtatatgta 55320 ttgtatatat gtaggtttta tgttgattgt atatgtggtt ttatattagt atatgtattg 55380 tatatatgta ggttttgtgt tgagatatta ttgtgttttt ttgatatttt gtttattttt 55440 ttgttgatgt tatattttga ttaatgtggt tttatagtaa gttttaatat aaagtttttt 55500 aaatatttaa aatattattt tgaatatttt aggttttttg agttttttta taaatttaag 55560 aagtagtttg ttgatgttta taaaaatgta gtgtgaattt tggttgagat tgtgttgaat 55620 ttgtagatta attaaggaag aattggtatt ttaataatat tgagtttttt gtatagatgg 55680 tatatttttg ttttaaaggt ttttttgtat tttttttatt tttttattga aaaaaaattt 55740 ttatagaatt atattgtttt gtagttttta agaaaaagat tttgtatgtt atttgttaaa 55800 tttattttta agaattttat ttttggtatt attttaagtt gaaatagatt ttaaatttta 55860 tttttaatta tttgttgtta gtatgtaaaa atataataga tttttgtatg taaattttat 55920 attttatgat tttttttaaa gttatttatt attttggtaa tggttttgta ggttttttag 55980 gatttaaata tatagtttta tttttttttg attttgatgt tttgtttttt ttttttgttt 56040 tattgtattg gttagagttg ttagtttagt attgaatagt agtgattagt ggatattttt 56100 gtttgtgtta aatttataat gttaatttta gatttgttat atatgatttt tgttagattg 56160 aggaaatttt tttttatttt taatttgttg aaatttttta atatgaatgg gtatgatttt 56220 agtaaatgtt ttttttgtat ttatggaaat gattattgtt ttgtttttta tttgtttaat 56280 aggataaatt ataatgattg atttttgttt tttgtttttt tttttttttt ttttaaagaa 56340 atagagtttt atttttgttt aggttgtagt atagtggtgt tattgtagtt tattgtagtt 56400 tgaatttttg gatttaagta atttttttat tttagttttt taagtagtag ggattatagg 56460 tatatgttat tatgttaagt taatttttaa tttttaaaat tttttgtata gatggggttt 56520 tattgtgttg tttaggttgg tttgtaattt ttgagtttaa gtaatatttt tatttttgtt 56580 ttttaaagtg ttgagattat aggtgtgagt tattgtgtag gtttgatttt ttaatattga 56640 attaattttg tatttttgga agaagtttaa tttgtttatg agatattatt ttttttatat 56700 attgttaaat ttgatttgtt tagtttttaa ggatttttgt gtgttgattt atgagggata 56760 ttggtgtggt attttttttg tttgttagtt tgttttggta atgtttttgt tagttttatt 56820 ttggttttat aaaattagtt tggaagtgtt tttttttttt tgttttttgt gtttttataa 56880 ggttgatgtt gttttttttt taaatgtttg atagaattta ttaagaaaat tgtttggatt 56940 tagaattttt tattaggaaa ggtgattgtt tgtttttaat tataaattta atttaatgta 57000 tagaaagagt tatttaggtt tttttatttt tttttgtttt atttttggta agttgtattt 57060 tgaaggaatt tgtttttttt aggtaagttg ttgaatttat ttatttaaag ttgtttgtaa 57120 tataagtata tttagggttt gtttttagat tttggtaata aagtaaatat tgtaataaag 57180 tatgttatat aaattttttg gttttttagt atatataaaa gttatgttta ggttaggtat 57240 ggtggtttat gtttgtaatt ttagtttttt gggaggttaa ggtgggtgga ttatttgagg 57300 ttaggagttt gagaatagtt tggttaatat ggtgaaattt tatttttatt agaaatataa 57360 aaattagttg ggtgtggtgg tatatgtttg tagttttagt tgtttgggag gttgaggtgg 57420 gagaattgtt tgaatttggg aggtggaggt tgtggtgagt tgagattata ttattgtatt 57480 ttagattggg tgatagggtg agattttatt ttaaaaaaaa aagaaaaaag ttatgtttat 57540 attatattat agtttattaa agtgtataag attattatgt ttttttgtta aaaaatgtta 57600 ataattattt gagtttttag taagttataa tttttttttt ggtagaaggt ttgttttaat 57660 gttgatggtt gttgattagg tggtggttgt tgaaagttga aggtagttgt ggtagtagtt 57720 tttttgtttt tttttttttt tttttttttt ttgagataga gttttgtttt attgtttagg 57780 ttggagtgta gtggtatgat tttagtttat tgtaattttt gttttttggg tttaagtaat 57840 ttttttgttt tagttttttg agtagttggg attataggtg tttgttatta tgtttggtta 57900 atttttgtat ttttagtaga gatagggttt tattttgttg gttaggttgg ttttaaattt 57960 ttgattttag gtgatttatt tgttttggtt ttttaaagtg ttgggattat aggtgtgagt 58020 tattgtattt ggttggtagt tttttaattg aagtttttga tatgggttga tttttttttt 58080 tatgaaagat ttttttgtgg tatgtattat gtttgatagt attttattta taatagagtt 58140 ttttttaaaa ttagagttaa tttttttaat tttggttatg gattgattaa ataagttgat 58200 gtaatatttt aaattttttg ttgttatttt aataatgttt atagtatttt tgtttggagt 58260 agattttatt tttaggaatt attttgtttg tttatttata agaagtaatt ttttatttgt 58320 ttaagtttga ttatgggatt gtagtaattt agttttattt ttaggtttta tttttaattt 58380 tagttttttg ttatttttat tatatttgta gtgatttttt ttgttgaagt tttaaattgt 58440 ttatttatga gggttggaat taattttttt taaatttttg ttaatgttga tattttaatt 58500 tttttttgtg aattataagt gtttttaatg gtatttagaa tggggaattt tttttagaag 58560 gtttttaatt tattttgttt agatttatta gaggaattat taattatggt agatattgtt 58620 ttataaaata tattttttaa ataataagat ttgaaaatta aatttatttt ttttttatgg 58680 gttgtagaat gggtgttata ttagtaggta tgaaaataat atttattttt atatatattt 58740 ttgttagagt ttttgggtta taaggtgtat tgttaatgag taataatatt ttgaaaggat 58800 tttttttttt tgagtagtag gttttaatga tttttttttt tttttgatgg agttttgttg 58860 tgttatttag aatggaatgt ggtggtatga ttttggttta ttgtaatttt tgttttttgg 58920 gtttaagtga tttttgtgtt ttagtttttt gagtagttgg gattataggt atatattatt 58980 atgtttggtt agtttttgta ttttttgtag aaatagggtt ttattatgtt ggttaggttg 59040 gttttgaatt tttgatttta ggtgatttat ttgttttagt tttttaaagt attgggatta 59100 taggtatgag ttattgtatt gggttttatt tgtttttttt ttgttgttgt tttttaattg 59160 agatagagtt ttgttttgtt gtttagattg gagtgtagta gtgttatttt agtttattgt 59220 agtttttgtt ttttaggttt aagtgatttt tttgttttag ttttttgagt agttgggatt 59280 gtaggtgtgt attattatgt ttggttaatt tttgtatttt taatagagat gaggttttat 59340 tattatgttg gttaggttgg ttttgaattt ttgaatttag gtgatttgtt tgttttggtt 59400 ttttaaaatg ttgggattat agttgtgagt tattgtgttt ggtttttttt tgtttttttg 59460 ttttttttta aattgagata gagttttttt ttgttgttta ggttggagta tagtggtatg 59520 attttggttt attgtaattt ttgttttttg ggtttaagtg gtttttttgt tttagttttt 59580 taagtagttg gaattatagg tgtgtgatat tatgtttgaa taatttttgt atttttagta 59640 gagatgtggt tttattatgt tggttaggtt ggttttgaat ttttgatttt aagtgatttt 59700 tttgttttag tttttaaaag tgttgggatt ataggtgtga gttgttgtat taggttttaa 59760 tgggttttta atatttagta aattatgttg taaatagatg tgttgttaag tagggtttgt 59820 tattttattt ttgaagtata gatagaatag atttggtaga atttttaagg gttttaggat 59880 ttttggaatg gttaatgagt attggtttta atttatggtt aatagttgtg ttagtttttt 59940 atgagagtta gtttgttttt tgaagtttta aagataggta ttgatttttt ttttttagtt 60000 atgaaaattt tagatgatat ttttttttag tagaaggtgg gatatttatg ttgaaatttt 60060 gttgtttagt gtagttattt ttattagtgt tttgagttag attttttggg taatttgttg 60120 ttgttttttt attagtattt gttgttttat tttgtatttt tatattatag agatggtttt 60180 tttttttaaa ttttatgatt tgatttttgt tagttttaaa tttttttttt ttagtttttt 60240 tatttttttt agtttttata ttattgaaga gagttagggt tttgttttgg attaggtttt 60300 tgtttaaggg aatgttgtgg ttgatttgat tttttattta gattatttaa atttttttta 60360 tattagtatt aaggttgttt tgtttttttt ttttttatgt gtgtattgga attgtatttt 60420 taattttttt taataatttt tttttggtat ttataatttg gttagttatt tggtataaga 60480 gattttattt ttgtttgttt tggtttttga tatgtttttt ttatttagtt taattatttt 60540 tagtttttga tttaaagtga gagatgggtg attttttttt ttatttgaat atttagaggt 60600 tattgtaggg ttattaattg gtttaatttt aatattgttg agttttaggg aatagggatg 60660 tttgagtaga gggagagaga gtggggaata gttagttagt ggagtagtta gaatatataa 60720 tgtttattga ataagtttat tgttttattt ggatgtggtt tgttatgttt taaaaataat 60780 tgtaataatg gtattgaaga ttattgatta ttgggtgtgg tggtttatgt ttgtaatttt 60840 agtattttgg gaggttgagg taggtggatt atttgaggtt aggagtttga gattagtttg 60900 gttaatatgg tgaaattttg tttttattaa aaatattaaa attagttagg tgtggtggtg 60960 ggtgtttgta gttttagtta ttggggaagt tggggtagaa gagttgtttg aatttgggag 61020 gtggaggttg tagtgagttg agattatatt attgtatttt attgtatttt agtttgggta 61080 atagagtgag attttatttt aaaaaaaaaa aaaaagggtt gggtgtagtg gtttatgttt 61140 gtaattttag tattttggga ggttgaggtg ggtagattat gaggttaggg gattgagatt 61200 attttggtta atatgatgaa attttgtttt tattaaagat atgaaaaaaa tagttgggtg 61260 tggtggtggg tgtttgtagt tttagttatt tgggaggttg aggtaggaga atggtgtgaa 61320 tttgggaggt ggagtttgta gtgagttgag attgtgttgt tgtattttag atagagtaag 61380 attttgtttt aaaaaaaaaa aaataaagaa agaaaaaaga aaaaagagat tatagattat 61440 tatagtagat ataataataa tgaaaaagtt tgaattattt taagaattat taaattttta 61500 tatagagata tagtgttaat atgttgttgg aaaaatggtg ttagtagatt tatttgatgt 61560 agggttgtta tgaattttta atttgtaaaa agtgtagtat ttgtgaagta taatgaaatg 61620 aggtgtgttt gtgttttttg ttattgtaat gttggtagga tttgtaagga aaatatttta 61680 ttttttttat tgtgatttta tgtttgttat ttttttttta ttagtagttt ggttaggagg 61740 ttattaattt agattttttt aaagaattag tattggattt tttttttttg gtgtttattt 61800 ttttgagttt ttttgttatt tttattattt ttttttttgt atttgtttta gtgtattagt 61860 tagggtttag ttaggaaata aaaattatat tggtaatttg aatagtaatt tgtaatataa 61920 agtgttttta attgtaagag gtagttaatt attaaaggga ttataaaggg gtgatattgt 61980 gatataagaa agatgtattt gggttgggtt tggtgtagtg gtttatgttt gtaattttag 62040 tattttggga ggttgaggta ggtggatttt ttgagtttag gagtttgaga ttagtttggg 62100 taatatggtg aaattttatg tttattaaaa atataaaaaa ttattttggt gtggtggtgt 62160 gtgtttgtgg ttttagttat ttgggaggtt gaggtgagag gatagtttga gtttgggaag 62220 gtagatgttg tggtgagttg agattgtatt attgtatttt agtttggatg atagagggag 62280 attttgtttt aaaaattaat gtatttgttt gtttgtttgt ttatttattt atttatttat 62340 ttatttattt atttatttag tttttgtttt ttaattttgt ttggtatgta gtttttaaaa 62400 tttttgaaat ttttaaagtg atgggtgttt ttttgtttgt taaggaggtg attggtggtt 62460 ggaggttttt ggatagtttg gggataaggg ttggttgtta ggggatttag ttttgtgatt 62520 agaaggttag aatttgtagt tttttttatt tattttttgt gaggtaagag gggatgaagg 62580 ttgagttgat tattaatggt taaagatttt atgttatgtt tatgtagtga agtttttttg 62640 aaaatttaaa aggatgaggt ttgtagagtt ttaggttgtt gaatatttgt aggtgttggg 62700 agggtagtgt atttttttgt ggaagtttta tgttgttttt tttatatttt ttttatgtat 62760 tttttttagt tggttgttta tttgtatttt ttgaaatatt atttgtaata agttagtaat 62820 tttaagtaaa ttgatttttt gggttttgtg agttatttaa gtaaattatt gaatttgaga 62880 agggagttgt gaagatttta aatttgtagt taagttagat agaagttatg ggtaatttgg 62940 tgttttatta tttgtgattg atttttgaag ttgagggtag ttttgtgaga tggaattttt 63000 aatttatggg atttgtatta attttggttg gtgttagaat tgaattgaat tgtaggatat 63060 ttagttgggg attgttgagt attggagaat tgtttggggg ttggtgggag gaaattatat 63120 atttggtgtt agagttgaag tattgagtgt tgtgaatgag agtggagaga tagagtttgt 63180 tttgttttat gtaagaggat tttaaggagt atagaaagag taaatatgag aagtagttat 63240 tttagaagaa aatataggag gaaagttttg tgatattgga gttggtaatg tttttttgga 63300 tgtgatattg aaaatataat aaaagaaata aatgataaat tggattttat taaaatttaa 63360 aatttttgtg tattaaggaa tattattaat ggtgtgaaaa ggaaatttat agaatggaag 63420 aaagtatttg aaaattgtat atttgataaa ggattagtat ttagaatata taaagaattt 63480 ttataattaa gttataaaat aaaaaaaaat aatttagtga atagatattt ttttatagaa 63540 gatatattaa tggttaagaa gtataggaag agatgtgtag tgttattaat tattagggaa 63600 atgaaaatta aagttataat aaaatatgat tttatatttt ttaaggtggt tgttagttaa 63660 aatatggata atagtaagtg ttggtaagga tatggagaaa ttggagtttt gtgtattgtt 63720 ggtgggaatg taaaatggtg tagttgttgt ggaaaagata taataattgt ttaaaaaatt 63780 aaatttagaa tgattataat atttagtgat tttattttta gatgtatatt ttaaagaatt 63840 gatagtaggg atttgaatag gtgtgttata tttttgtttg tagtagtatt ttttttataa 63900 ttaaaagatg taggtaattt aggtgtttat tagtggatga atgaatagat aaaatgtggt 63960 ttatttgtat agtggaatat tattttgttt taaaaaggaa ggagaggtta ggtgtggtgg 64020 tttatgtttg taattttagt gttttggaag gttgaggtgg gtagattatt tgaggttagg 64080 agtttgagat tagtttggtt agtatggtga aattttgttt ttgttaaaaa tataaaaatt 64140 agttaggtat gggggtatgt gtttgtaatt ttagttatta gggaggttga ggtaggagaa 64200 ttgtttgaat tagggaggtg gaggttgtag tgagttgaga ttatgttatt gtattttagt 64260 ttgggtgata gagtaagatt gttttaaaaa aaaaaaaaaa aaaaaaaaaa aaggagattt 64320 tgatatatgt tatagtatag atgagttttg aagatatgtt aagtgataga agttagatat 64380 gaaaagataa atattgtatg attttatttt tatgaggttt ttagagtagt taaatttaga 64440 gagatagaaa gtgggatgga ggttgttaga ggttggggga agggagaatg aatgggaagt 64500 tggtgtttaa tggggataga attgtagttt gggaagatga gatggatggt ggtgatggtt 64560 atataatagt gtgaatgtgt tttatgttat taaattgtat atttgaaaat ggttaaaatg 64620 gtaaattttt tgtgatggat attttaaggt atgtatgtaa atatatagaa gtagttatta 64680 ttattggggt tgatggaaaa gaaattaaga atttggagtg ttttttatat tttgttatgt 64740 tttatgttta ggttttgttg gagagtgtgt gattgttata gaaatttgta gtttattggt 64800 aataaaaagg tttttgttag aaggtgtaga aagagtggat ttgtaggatt agtttattgg 64860 gtagttgaga aatttattag agggtatggg tgggtaggag ttgggtgttt gagaagtttg 64920 ttgaggtttt attgggttag agttggggtg ttggagaaat ttagtataga gtaggtttta 64980 ttgggtatat gttattggta gttgtgtttt tagaggaaaa agagattttg gaattaggaa 65040 gagaagttgt tattttagta aggtttggta gttttttata gtgttgtttt ttgtggatag 65100 agtttgatat gattgtattt ggttaaggag aaagatttat aaggttttgg tttagtatta 65160 tggagtgggg tttggtagga tgtatgtaga gttaagaggt aatatatggg taattggtat 65220 atttttttag attttttgtt ttttttgttg ttttgttttg ttttgttttg ttttgttttg 65280 ttttgagaga gtattttgtt ttgttgttta ggttggagtg tagtggtatg atttaggttt 65340 attgtaattt ttattttttg ggtttaagtt atttttttgt tttagttttt taagtagttg 65400 gagatgttta ttatgtttag ttaatttttg tatttttagt agagataggg ttttattatg 65460 ttggttaggt tggttttgaa tttttgattt taggtgattt atttgttttg gttttttaaa 65520 gtgttgggat tataggtgtg agttatattg tatttggttt atttttttag atttttaaag 65580 tagattttta ggtttttttt tttttttttt tttttttttt tttatttttt ttttaatata 65640 agtatttata gttttttttt aagtattagt tttagtttat gtattttagt atgttgtgtt 65700 tttattatta ttttatttga aatattgtaa aatttttttt gtgatttttt ttttgattta 65760 tgggttattt agaagtatgt tgtttaattt gtaaatagtt aaggtttttt tgagtatttt 65820 agagttattg atttttaatt taattttatt ttggttagat aagtatattt tgtatgtttt 65880 taaaatttga gatttatggt ttagaatgtg tattttggtg aatgtattgt ttttatttga 65940 gaaaaaaata tgtatatata ttttagattt tttgagtata gagttttata attgttgatt 66000 aggttaattg ttagttatta gtgtttttta gattatttga tgtttgtttt ttagatgttg 66060 agagaatggt gtttgttatg gtttatttgt ttgtgttttt taaaatttat atgttggagt 66120 ttaatttttg gtgtagtggt gttgggaatt ggggtattag ggaagtattg gtttatgagg 66180 gtagagttat tgtgaatggg attagttttt tttgttatgt ggggatatag taggaaaagg 66240 atatttttga agtagggagt tagtttttat tagatattga gtattttgat tttggatttt 66300 ttagttttta gaattgtgag tattataatt tgtttataaa ttatttagtt taaggtattt 66360 tgttttaata ttttgaatga attgaggtgg tgttaaaatt tttaattatg tatttaggtg 66420 tagtggttta tatttgtaat tttagtattt taggaggtta aggtgggtgg attatttgag 66480 gttaggagtt tgagattagt ttggataata tggtgaaatt ttgtttttat taaaaatata 66540 aaaattagtt gggtgtggtg gtaggttttt gtaattttag ttatttggga ggttgaggta 66600 ggagaattgt ttgaatttag gaggtggagg ttgtagtgag ttgagattgt attattgtat 66660 tttagtttgg gtaataagag tgaaattttg ttttaaaaaa aaaaaaaaag agtttttatt 66720 tatgattgtg gaattgttta tttttttttt taattttttt aggttttata ttatgtattt 66780 tgaagttttt ttggttaggt gtatatatat ttatgattat aatggtgttt tgatgaattg 66840 attatttaat tatgatgaat gtattttttt attttgtaat aattttattt tggatttaat 66900 tttattgata tttatgtagt ttttttagtt tttttaaata tgttgtttgg gatgtataag 66960 aaggttggag aggtttatgg agaaatttat gatggtttga tttatagttt tttaatttta 67020 ttatggtgtg aatgtggtat gtatatagta gaaattgtat tttaagtatg tgtgaaatta 67080 ttgtgttttt tatttttagt atagtattta ataatttata tgagatagtt aatattttat 67140 tataaaatag gttttgtgtt tgttgatttt gtttaattgt aggttgaagt aagtgtttta 67200 attatgttaa ggtaggttag gttaagttag aatgtttggt aagttagatg tattaagtgt 67260 atttttgaga tgatatttat tttttattta tgatgggttt gttaagatat aattttatta 67320 ttatttaagt agtattagta tgtttttttt taaatagaaa attttaattt gtgtttatat 67380 tgaaatagta ttttttgtag atagtatata gttgagtttt gttattttat ttattttgat 67440 agtttttgtt ttttaattgg aatatttagg ttatttttgt ttaatatagt tatagatatg 67500 attgggttta gagttattat tttgtttttt gatatttatt ttttttattt tgtttttttg 67560 gtttttttta tgttaattaa gtatttttta gaattttatt ttaatttatg tttttttttt 67620 tttttttttt ttaagataga gttttatttt gttgtttagg ttggagtgta atagtatgat 67680 tttggtttat tgtaattttt gttttttggg tttaagtgat ttttttgttt tagttttttt 67740 agtatattgg gattatagat gtttgttatt atggttggtt aatttttgta tttttagtaa 67800 agatggggtt ttattatgtt ggttaggttg gttttgaatt tttgatttta ggtgatttgt 67860 ttattttggt tttttaaagt gttgggatta taagtgtgag ttattgagtt tggtttgttt 67920 tgatttttta attgtatttt tttgtattgt tattttagta gttattttat agattttatt 67980 gtatattttt agttttttat agtttattta gaattaatat tgtttttttt tatggaaaaa 68040 aagtgtaaga attaggtaat tttatgggtt tatttattat tttttatttt gtatgtgatg 68100 gttgttagat atttattata tttatatata ttgtaaatta gataatataa taaggaaatt 68160 tttgttttaa atagttttat gtattttaaa gaaattaaaa gtaaaataga atttttttta 68220 tttgtttatg tatttgttat attttgtgtt ttttattttt ttttgaagag ttgagttttt 68280 atttggtttt attttttatg attttggaga atttgtttta tggtttttgt agtgtaggtt 68340 tgtagatagt taattttttt ttatttttat ttatttgtaa atttttattt tgttgttatt 68400 tttttttttt ttatttttat ttttattttt gagatagagt tttattttgt ttttttatag 68460 gttatagtgt aatggtgtga ttttaaaatt tttgtttaat tttaatttat taattttttt 68520 tttttgggtt taaatgattt ttttgtttta gttttttaag tagttgggat tataggtatg 68580 tgttattata tttagttaat ttttgtattt ttagtagaga tgggatttta ttatgatggt 68640 taggttggtt ttgaattttt gattttaagt gatttgtttg ttttggtttt ttaaaatgtt 68700 gggattatag gtgtgagtta ttgtgtttag tttgttgtta tttttgaatt ataattttat 68760 tggttataga attttgagtt gttagttttt ttttttagga ttttaaaata tagggtttta 68820 gtgtttttgg tttttgttgt ttttgttaag gaattagtat ttatttagtt atttttttgt 68880 agattatatg ttgttttttt ttggatgttt ttaagatttt ttatttaagt ttgattgttt 68940 agtatttatt tttgggtaaa aaagttttta gaaattagaa atttatttag ttttattttt 69000 ttttgttagg tgtagatttt attttagttt ttatttattt gagatatttt atattgattt 69060 taggttgttg ttattttgtt tttttaaata ttttgtttag agttataatg ttttttgtag 69120 aattgattag atagtagtta ttttttgtga ttaggagttt tgatttttta gatttgttga 69180 tgggtttata aagtttttgt ttgtggtttt tagttggtag tggttttttt gttttgaagt 69240 tgttatgagt gtgtaaaatt tataggttta atttttttta ttagtatagt ttagaaaagt 69300 ggaatttttg gtttgggtgg ttatggtgtt ttagattatt ggttagatta gggtggtgat 69360 tgttagttgg ttgaatgtgg ggtttttagt ttagtatttt tggattttat tttaggagtt 69420 atggttgttt tagggttagg ggtttggttt tagtttttgt tttttttttt ttttttttaa 69480 gttgtttagt attaggtttt aattagtatt ttttgtagat agggtgggtt ggttttttat 69540 tagaggggta gggttgggtg ggaagtttgt tgagtttttt tttttgtgta gtttatagtt 69600 ttggggttag ttttagaggg gtgtagaaag gagtttttaa aggtagaaat ttattttttt 69660 ttttgttttt gtgtttttag ggataaagga gaggtggttt tagttggggg gttattagtg 69720 gtatgtagga ggtttatatg attattgttt gttggggttt tttttttttt gtgagagaga 69780 tgagagagag gagagagagt gtgagttagg gtagtgtttt tttttagtaa tgtagatttt 69840 tgtatgtgtt ttttaggaga aattttgtta tttgttagag ttttagattt ggaagaagtt 69900 ttgttttttt tttttttttt agtgtagtgt gtgtgtgtgt gtgtgtgtgt gtgtttttat 69960 atgtattata tttttttata gaggaaataa tttttgttta agtgtaaagg ttgggattgg 70020 agtaggtagt atgtgggtta aaggagtaga gaggaggaaa tgggggtggg ggtgagggtg 70080 ggaataggag gtgggtagat gttatgaggt atgtttttta taattagaag ggttggtgga 70140 gatgattaga atgttttaga tagatttttt attaaatttt taaaatttaa ttttgtttta 70200 tgaagtttga ggattttgta gagtgaaaga taaggaaggg tttttttgta ggggggtgtg 70260 tgtgtttgtg tgtgtttgtg tgttgtgtgt ttttatgtgt gtgtatgtgt ggatttgtgt 70320 ggtgtgtgtt tgtatatgtg tgtatgtgtg gatttgtgtg gtgtgtgttg agtgtgtata 70380 tgtgtgtgtt tgtgtgttgt gtatgtattt gtatatgtgt atatagattt tatttttttt 70440 ttttttggtt tattaagtgt tagaaagaat ttttgtgagt ttttttattt tttttaaggt 70500 tgtatatgga gggatttgtg taggtatatg tgtgtgtgta tataatatat atatatatat 70560 atatatatat atatatatat atatatgagt taggggtgag tatttttgtg gattgtattt 70620 aggtttggta ggaaattggg ttttgggaaa ttgtaggttt tatttttggt agaaaattat 70680 gtttttgttg ttgtttgttg aagggaatat taagtggggt tggggatagt ttatgttgag 70740 aagagtaaat tttgtttatg gtattgggga tattgagtgg tttttgtttt gggttttgga 70800 gggtttggga gatatgtttg tagttttggg tattttttaa ggttatgggt ggttatattt 70860 aaggttaggt ttttttttgt gtgagttgtg gttagtagga aggttgattt tagaggtggt 70920 tttagggttt ttggaggttt tgtttttgag atatgggtta aggttagaga gttgagaagg 70980 ttgttgttga ggattttggt tggtgtttag tttagtggtt ttttaggtgg gttttgtgta 71040 ggggttgatg aagttagttg ggaaatttgt gaaataaagt ataggttttt taggtttgtt 71100 tagagttttg gtattagatg aggtgtagag aagggaattg agttgttaag tgtgaatagg 71160 agagaggagt tttaggatta tataggggtt ttgatatggt aggtgtttgg ttagtagtgg 71220 tgttgttttt attgttggat gtgggaaaat gtattgatat ttgttgatta gagttggggt 71280 gagtatttgg gtgattttgt agatgagata aaataagggt tgttgtgggg gaggggtttt 71340 tgttgggtta ttttgttgag gttttgtgtt attgttttgt ggttgttata ataaaggatt 71400 ataaatgagg tgatttaaaa tatttgaaat tggttatgtg tggtggttta tgtttgtaat 71460 tttagtattt tgggaggttg aggtggttgg attatgaggt taggagattg agattatttt 71520 ggttaatatg gtgaaatttt gtttttatta aaaatataaa aaaaaaaaaa aaattagttg 71580 ggtgtggtgg tgggtgtttg tagttttagt tgtttaggag gttgaggtag gagaatggta 71640 tgaattttgg aggtggaggt tgtagtgagt tgagattgtg ttattgtatt ttagtttggg 71700 tgatagagta agattttgtt ttaaaaataa aaataaaaat aaaaataaaa atatttgaaa 71760 tgtttttttt aaagtttttg gagttagaaa ttttagattg aggtgtttga aggtttattt 71820 tttttggggg ttttgaggga gattgtttta tgtttttttt tgagttttgt ggtggttagt 71880 aatttttggt attttttggt ttgtagtttg gtttattttt tatttggttt ttattttgtg 71940 tttttttttg tgtttttgtt taaattgttt tttttgttgt ttttttaatt tatttttagg 72000 gataggtttt tattttgttt tttaggttgg agtgtagtgg tgtgattatg gtttattgta 72060 gttttagttt tttaggttta agtaattttt ttattttagt tttttaagta gttgggatat 72120 aggtgtatgt tattatgttt ggttaatttt ttaatttttt tgtagagatg agggtttagg 72180 ttggttttaa atttttgtgt ttaggtaatg agattttgtt ttttaaaata ttgggattag 72240 agatatgagt tgttgtgttt agtttatttt tgttttataa agatatttgt tattggattt 72300 agggtttatt ttgatttaat atgtttttaa ataatttaat tatattttta aagattttat 72360 gtttatataa agttatattt ataggtattg gggggttagg atttgtatat gttttttggg 72420 ggaatataat ttaatttata atgggtttta tttatagaat gaatggtttt tttagggtgt 72480 gtgtaggtgg gtgaggggtt taggagaggg atttgtgtgg taagagggtt tgtgtttatg 72540 ttagagattt tagaaggaga ttggatgggg tggttgtatg gagtaagggg ttatagttat 72600 tgtttttaag tagttggtgg gttgtttggt agaaagggag tatttatttt gagttttttt 72660 aagatatgaa gttagtatta ggtatttgga aggtgttagt gagtagagtt tgatttttta 72720 tagaaagagg tgtttttttt ataatgttta tttgaggatg gtggaatagg ttattttata 72780 aggtagtgag ttttttatgt ttggaagtat ttaagtaggg gttatgtggg agttgtttag 72840 gagtgtatag aagggatttt agaggttttt gttaatatta tttttgtttg ttttatttta 72900 tgataatttg aattttagaa tgtaatgtta ttggggatat gtttattaga ggggttttta 72960 gtattaggtt ttatatatta tgtattattt ttagggtagg gaatgagagt aggttttatt 73020 ttttttggtt gtttgtgagg attaggaggt ttgttgttga ggtagttttt tgtggaaata 73080 gtgttttagt tttgtaattt atttattgga gttttaatat tttaatgaaa tattgtgtta 73140 gatgggtttt gggtatgtgt gtgtagattg ttataagttt atgagaatgt atatatgtat 73200 attgtatgtg tgtgtatata tgtatgtata tatgtataag aatatgaaga tttgaggtag 73260 gtatagtttg tgagatagat ttttttaggt tgaaagattt tttataaggg tttttagaat 73320 aaggttttag ttttggtagt tttttttatt tttggtggga ggatttttat agagaagaag 73380 ggttaagaag tatagttttt gatgtttatg gtgtattaag ttttgtttta agtttgtgtt 73440 ttatttttta tttatttagt aaatttgttg tttttgtttt gtgttagatg ttgtttttag 73500 tattttataa atattgatgt atgtttgttt tatgataatt ttgtgaagta ggtagtgtta 73560 ttttgtttta tagatgagga aataggtgta gagggataaa gggatttgtt taaggtttgt 73620 ttttatttta tatgtatatg aatgtttatt tatgtggtag gtgttagttt ttttttgatg 73680 tgagttaggt tttgagttgg ttggggtttg ggttttattt tggttgtgtt ttgttgtggg 73740 tattaaggaa gtttttagta gttttatttt tttggtatga tttagtttta gggattggat 73800 ttttttaaat gtttttgttt agtttggagt ttttttttta gttgggggag ggttgaatga 73860 ttttttattt ttggaggttg ttggagtttt ttttgtttgt atgtggttgt tgttgggtgg 73920 ataggtttgt ttgtgggttg aggtttttag tagttggggt ggattatttt tttttttaag 73980 aagttttggg agaagtagtt gagggggtta gtgttttttt gaggttaatt ttttgttttt 74040 tttagtgtag gtgtgaagtt atttttgttt gtgtgtttgt tatagatagt ggagggtggt 74100 gtaattgtga tgtttgtttg ttgtattttg tgtttttgag gatgttgatt tttggttggt 74160 gttgggtgtt tgttttttag ttattttgtt ttgatttggt gtggtaggtt tgagtattgt 74220 ttttttataa ggaaataggt ttagaggttt tgagttattt gtttgggttt ttttagttaa 74280 taattggttg agttaggatt tttatttagt tttgtgattt tagaagttta agtttttttt 74340 attatgttag ggttaggaaa ggattagaat gtttttttat gtgttgatta tttggatgat 74400 ttgtgtagtt tagtttgttg tagttgttta ataaaaatgt ggaatgaatg ggtttatatg 74460 ttttattgtg tgatttagag ttaatgattt tggttgattt ttttgttttt attttgtggt 74520 ttagtatttt tttttggggt gtgtgatttt ggaagtagtg atttttttta ttttattttg 74580 aatggtgttt gtgttgtagt aggggagtag ttggggattg ttagtgtttg ttgttggtgg 74640 gttgtgtgtt agattttgtt ttggatgtgt gggtgattgt tagttatatg tgtgtgaagg 74700 gttgtgtgtg taggatttgt gtaaatgtgt ttttttttgt tgttagttta tgggaggttg 74760 ttaagatttt gtttttgtat attagtttat attttttttg tggtttattg ttgtggttgt 74820 ttttttgtgt tatgtggttg taggtatagt ttttaagtgg atggggattg tgggttgaat 74880 gtgtattaga tgtttttgtt ttttggtggg tggagatttt taatttatgt attgtggttg 74940 ttgtatttga aaggtttttt atggtgaagg atttggattt gagtaatttt ttgtagaggt 75000 tttagaagtg ttttttggtt gggtgtggtg gtttatattt gtaattttag tattttggga 75060 ggttgaggtg ggtggattat aaggttagga gattgagatt attttggtta atatggtgaa 75120 attttgtttt tattaaaaat ataaaaaatt agttgggtgt ggtggtgggt gtttgtagtt 75180 ttagttattt gggaggttga ggtaggagaa tggtgtgaat ttaggaggtg gagtttgtag 75240 tgagttgaga ttgtgttatt gtattttagt ttgggtgata gagtgagatt ttgttttaaa 75300 aaaaaaaaaa aaatgaagtg tttttagttt ttttttttgt ggtgaggttt tgagttttta 75360 tttttagaag aaaatttggt tggggagggt atttttagat ttggatataa atgttaggag 75420 attagggttg tttttttagg tgattaatta tagagattta gggaaagtta tgtttggaag 75480 aggtgatatt gtgttttagt tttatttatt tttttatttt atagatattg tttggtgttt 75540 agtttgtatt gtgaggtttt ttaagtagtt ttgggtattg tgtatttggt atggttttta 75600 gttttatttt tttgttttgg gagatttggt ggggattttg ggttgagttt ttgtggttgt 75660 ggaattttgg tggtttattg tggtggttga gaatagggat gtggggttgg atgggttgag 75720 tgtaattttt agtggttttg tgaattgttt gggagttttg ggtagttttt ttttattttg 75780 tgtttttgtt ttttgatgga aaaatggggg ttagggggga gtgattttga aggtatttgt 75840 gggaattaag tgaggtgata aatgtagtgt ttttggtaga gaattggata tagagtttat 75900 ttttatgaag ggggttgttt tttttttttt tatgtttttt tttgttttta tttttttttt 75960 tgtatttttt ttttttgttt tttttttttt tttttttttt ttttatatgt aggtatattt 76020 tatttggtgt tttaattgtt tttttttatt gtttttttgt aagtggtttt ttaagtggga 76080 atttaggttt ggaaagggtg ggtattttgt ttggtgggtt ttggtaggtt aggtgttgag 76140 tagttttagg agatataatt ttaggaaaag gtttatgtag gttggttgtt atgatggatt 76200 gttggtggga gaggggaagg tgttgtggta ggggaagttt tggaaatatt tattagtggt 76260 tttatttatg atttaggata tttgttaggt tattagaata tagttgagga agttgttggt 76320 tagatgttta gaagtattaa tttggtggtt gggttgtggg gggatttttt tggataggta 76380 gataaggtgt tggaggaagg ggttgatatt tatttagtgt ttgttatgta ttgagggtat 76440 aaagggtagg atggagagtt ggtttatgtt atttgtggaa ttttttaggt gtgggggtag 76500 atggggaagt aagggggttt gaagatatat gtgtttatta aatgttttta aattttaaga 76560 agaagaataa ggatatattt ataggggtag ggttgaaagt ttgatgtatg gtgttttggg 76620 gtttgttttt gttgtaatag ttatagtggt ttttttttat tttttttttt tttttatttt 76680 gttgtgaaaa tgtttaaaat atatggttaa gttgaaagta ttttataggg aatatattta 76740 gttattattt agattttatt attaatatta agttatattt gttttattat tttattgttt 76800 atttattttt tttttgtttg gttatgaatt tattttattt ttattttttg gtgtatttta 76860 aagtaatttt aggttatttt gattattttt ggaattattg ttagaaattt tttttttttt 76920 tttttttttt tttttttttt ttttttttga gatgggattt tgttaggtta tttaggttga 76980 agtgtggtgg tgtagttata gtatattgta gtttttaatt tttgagttta agtaattttt 77040 ttgttttagt tttttgagta gttgggattg taggtattta ttattatatt tagttttatt 77100 tttaaaattt tttattaatt ttttattttt tgtatttatt taggattatt ttttataaag 77160 ttagggtgtt gtaggagggg ttagaatttt aagttttaat tttggttttg ttattaatat 77220 tgtgtgattt ttagtaaatt attttgtttg tttaggtttt gtttttattt ttatgaaatg 77280 agggtgttaa attgtatgtt ataaataatg agggttatta gttattaagt ttttatttta 77340 ggttaggtat tttttatatg ttattatgag tttttttaat ttaggtattg tttttaatgg 77400 atagtttagt taatggaagt ttagagaggt ggtgtaattt gttaaaagtt ttattattta 77460 gtgaatgttt ttatggggtt tgtatttagg agtttgatat agagtttagg ttttagtatt 77520 tggtgatgtt ttgggggtgt gagtagttta gtttattttg ggtatgtgtt tatttgttgt 77580 tttttttgtt ttatgtttgt gtttgttttt tttgaagttt agattgttat tttttagttt 77640 taaatattaa aattggttag gtatggtggt ttatgtttgt aattttagta ttttgggaga 77700 ttaaggtggg tggattattt gaagttagga gtttaagatt agtttggtta atatggtaaa 77760 attttatttt tataaaaaat ataaaaatta gttagatatg gtggtgtgta tttgtagttt 77820 tagttattta aggagaattt agttatttag ttattgaggt atgagaatta tttaaatttg 77880 ggaggtggag gttgtagtga gttgagattg tattattttt ttttaggtta ggtaataagt 77940 gtgagatttt gttttaaaaa taataaataa ataaaataaa ataaaaatta aaattaaatg 78000 ttaaaattaa tttataaaat aaattttggt taaagtagtt tgtttatttt gttttaatta 78060 tgtatattgt attagatttt gttaggggtt tagtgtataa agatgagatt tttgttttgt 78120 tagataggtg ggatgatggt tatattttga gttagttaag gtattatttg gttgtgtaat 78180 aaaagttaaa atattagagg ttgagtagta tttggattta tgttttagtt taagtgttag 78240 ttgttatggg ggtttaggat agtttggatt tagtttattt ttttggtgta tttttgatat 78300 atagttttta ttttttgagt tgagatggtt ttagtttttg ttgttatgtt tgtattttag 78360 ttagagggaa gggaagaagg gagaggggaa agggtaagtg ttttttttta tttttaaggg 78420 tatgatttga aagttaaata ttttagtttt tttttattgg ttagaattta gttgtatggt 78480 tgtttttgtt attagggagg ttgagtaatg tattttttag ttgggttttt ttgtgtataa 78540 ttaaaatttt agttattata gaaaaaaggg agtttagata ttggggaaat aattagtatt 78600 tgtattatat gtattgatag ttttttttgt atgaatagag ttgtggtagg ttttatgtta 78660 gggagaaagt aagattggaa aagagtttat taaggaggtg gtatttgtat tgtgtttaag 78720 gggtaagaaa aatgtttttt aattaggagt tataaatgtt tggttgaagt gttattgttt 78780 ttttattttg gagttggaat agatgttatt agttaattat gatggttgtt gggtgtattg 78840 gttaatattt ataattttag tattttgtga ggttgagggt gggaagattg tttggggtta 78900 ggagtttgag attagtttgg gtaaattgta agattttgtt tttgtaaaaa aatataaaat 78960 gtagttgagt gtggtggtat ttgtagattt agttttagtt atttgagagg ttgagatggg 79020 aggattgttt gggtttagga gtttgaggtt gtagtgagtt atgattgtat tattgtattt 79080 tagtttgggt gatagagtag gatttgtttt taaaaataat aaaataaaat taaagtttta 79140 aaatggaaaa aaaattatga gtatataatt ttagatgtat ttttaagata gtaaatttgg 79200 gtgggtgtag tggtttatgt ttgtaatttt ggtattttgg gaggttaagg tgggtggatt 79260 atttgaggtt aggagtttga gattagtttg gttaatagtt ttatttgtat tataaatata 79320 aaattagttg ggtatggtgg tgggtatttg tgattttagt tatttggaag gttgaggtag 79380 gagaattgtt tgaatttagg aggtggaggt tgtagtgagt taagattata ttattgtatt 79440 ttagtttgga gaaaaaaagt aaaattttgt tttaaaaaaa aaaaaaaaaa gtaaatttag 79500 ggttaggttt gtagttatat ggttattttt ttttttgagt atggaggtag ttttagaaat 79560 ttgttttata ttatattagt gggtagttga ttgggttagt ttgttagttg aattttattt 79620 gttatagtta ttttttatag taaggggtat tttagatata tttttttttt tagggaagaa 79680 taagttgtag ttgtttgagt gttttattta gtggtgtgta tgtttttttt taattttgtg 79740 tttagtgatg ttttgtttgt agtttgaaat ttgttatagt gggtgtgttt atattatagg 79800 aattggtaaa tattatatat taggttttat tttttgtttt ttattagggt aggttgtttt 79860 ttttttgttg tttttgtttt ttgttttttt ttttttttga gatggagttt tgttttgttg 79920 tttaggttgg tgtggagtga tgtgattttt gtttattgta agttttgttt ttttggttta 79980 tattattttt ttgtttgagt ttttagaata gttgggatta taggtgtttg ttattatatt 80040 tggttaattt tttgtatttt tagtagagat ggggttttat tgtgttagtt aggatggttt 80100 tgattttttg attttgtaat ttgttttttt tggtttttta aaatgttggt attatgttat 80160 tgtgtttggt ttagggtagg ttgttagaaa tgtattagtt tgttagtttt agttttgttt 80220 gttttttatt tttttttttt tttttttttt ttttgagatg gggttttttt ttgttgtttt 80280 ttaggttgga gtgtagtggt gtgattttgg tttattgtaa tttttgtttt ttgggattaa 80340 gtgatttttt tgttttagtt ttttaagtag ttgggattat aggtgtttat tattatgttt 80400 agttaaattt tgtattttta gtagagatgg ggttttatta tattggttag gttggtattg 80460 aattttttat ttaaggtgat ttatttgttt tggtttttta aagtgttggg attataggtg 80520 tgagttattg tattgggttt tttttgtttt tttttaatga aaattttttt gaaagatttg 80580 tttattgatg tttgtgttaa taggtattgt ttgtgggata gagtttgttt tttttttgaa 80640 ggtttttttt tgtttgggtg attatttgta tgttattttt tgttgtttag aattaaagat 80700 gtagttatgt ttggggtagg ttgggaaaat ttgtgggaat tatagagttt gttgttatgt 80760 tgtgttttgg atatttgaag tttggtaggt aggtgggatt gagggtgggt attaggaaag 80820 tgatgtggtt ttataggaag gggatatagg ttttgagatt ttaggttttt aattggataa 80880 agttgttttt tttttttgga taaatgtttt agtttattta taattgagtg gttagttttt 80940 tttttttttt tttttttttt ttttttgaga tggagttttg tttttttgtt taggttggag 81000 tgtagtggtg ttattttggt ttattgtaag ttttgttttt taggtttatg ttattttttt 81060 gttttagttt ttggagtagt tgggattata ggtgtttgtt attgtgtttg gttaattttt 81120 tgtattttta gtagagatag ggttttattg tgttagttag gatggttttg attttttgat 81180 tttgtgattt gtttgttttg gttttttaaa gtgttgggat tataggtgtg agttattgtg 81240 tttggttaag tggttagttt ttttagttgt tgggttttgt atattttgtt ggttttggag 81300 attatatgta ttatgtagat tttatttgtt ttttattttt agtgttgggg gaggggttaa 81360 gggtttgttg atgtgttgat atttggttat ttattggttt tgaatgttta tatttatttt 81420 tttgaaattg atgttttgta ttggaggttt tatgtggatt tgggggtaga ggtttgtatt 81480 ttagatggtg gggtggtttt tattaattag gtagattttt tgttttgttt tgttttttgg 81540 gttttgtagt tttagatgtg tgtttaagat ttgtggttat atggatggga taagttatag 81600 agatttagat tttgtggttt ttgtgattag agtagttgtg gttttgtttg ggaatgtttt 81660 tattttgttg ttgaaggtga gaaatttttt tgtgttggag aatagttgtg ttgagaagtt 81720 ggtttatttg gtttgtagga ttgttggggt aagggaggtt tgttgttggt tttttttttt 81780 tttttttgat tgggtgtttt ttgtttaggt tttttgtagt aaaagaattt tttaatttat 81840 tttgtttttt tattgagttt ttattttatg aagtttattt tttaatttta gttgattggt 81900 ttttattttt ttaagaggaa ggttaggggt agatgaggtt gaaggaggtt gatttttttg 81960 tgtttttgta gtttgagttg atgttgttgt atgtttatag ggttttttta gtttttaaaa 82020 aggttttaat atgtttgtta tatgtttgtg gtttttttgg atgttatatt aatttagtaa 82080 ggtttgagtt agaggttgtt tttgaggttg tgaaaataga agaagggttt agaggagaat 82140 ttttttattt gatgatttta ggaaggtttt ttagaagaag tagtttttga gttgagattt 82200 gaagatagat taggtttgag ttaggttagg gagggtgtga ggggtttatt aggtagaggg 82260 aataggatag ggtaggtata gaggtttggt atttggtttg tggggaagtg tgagtttttg 82320 ggtatgatta aggtggggag aagtggtgtg agaggaggta gatgtggttg gtaggagatt 82380 ggtggttttg gttttgttga gttttatttt gtatgtatta ggtgatagag gttgtttagg 82440 atggtgggta gggaagtgat aggttatatg gttattttat taatagttgg gagtttagtt 82500 tggggggatt taagattttg gggaaggtat gagttagggg tttgttagag ttaggagtta 82560 gtgggagaag gaaatagtgt tgtttatgaa ttataaatag atatttttgt aatttttttt 82620 gatgtgatat aattttaaag tgggttattt agaggtggga aggtgatttt tggtttttta 82680 ggttttgggt ttgttttttt tttttttttt tttttttttt tgagatggag ttttattttg 82740 ttgtttaggt tggagtgtag tggtgtaatt ttggtttatt attatttttg ttttttgtgt 82800 ttaagtaatt tttttgtttt agttttttga gtagttggga ttataggtat ttgttattat 82860 atttggttaa tttttgtatt tttagtagag atggtgtttt attatgttgg ttaggttggt 82920 tttgaatttt tgattttagg tgatttgttt attttggttt tttaaagtgt tgggattata 82980 ggtatgagtt attgtgttta gttgagttta tttttaagtt ttttttggtt tttagtgttt 83040 ttgtattagt ttattttttt ggttttttgt ttttaagagt tttttttaag attgttttta 83100 agtggatagg tttttagaat taaggagtag ttttaggagt ttttagttat agatatttta 83160 gggggtttgt gtggttttta gtttttggtt tggttttggt agttttggtt ttttgtgttg 83220 ttttttatat agtttggtta gagttggtta ggttttttgg ttgggttgag ttattgtggt 83280 tagtgattta tgtaggggga gaaaagtgag gagggggaat agagtgtgag ggggattgtg 83340 ttaataataa atttattagg tttttgaggt tattttatag gagggataaa tggtttattt 83400 aggttgattt ggttgttggt tggtttttag agatatttag ggtggggaag attttattat 83460 ttggggaaag taatattaga ttgtttggag gggtttagtt agtgtatttt gtgttttttg 83520 tttgtttttt atgtagagtg ttttgttttt aaggtggtag gttaagagtg tgagttgagg 83580 tttaggtgta aagaggggtg tggtatgggg gtattgtagg gtatggggtg tatgtatttt 83640 tatttatttt tttattgagt gttagggtaa tttgttaatg gggtatattt ggtgatataa 83700 aattttttgt tgatttatgg tagtttggaa tggagtggaa gtgttttatt tttggggaat 83760 ttttatatat atttggttgt gaatgttggt gtttttgtat tggagttttt ttggagtgtg 83820 ttgggtagag tggagaggtt tttttttttt tttttttatt attttgtgga ggtgttaata 83880 tgtagttaga gatggttagt ggtagtgagg agaggggggt aggaagagat tagggttggg 83940 ggtttgttag tttatagttt tatttttgaa tatttatggt ttttttgttt aggttagtga 84000 ggttgggggt agagatgggt aggggttttt taatgttggg tatttttttg tttttttata 84060 ttttggattt gttttttgga gaaagttttg gagtatttag aagttttggg gttgttggtt 84120 gaggtgggga gtagagttta gttgtgtttg gaggtttttt atttttattt agtttttagg 84180 gatagtttta gttgtgtagg tttaggttgt tgaggttggt tttagaaatt tttttataat 84240 tattattgga tggaaaatta gttttttaaa gggttttaga gttagttttg tttttttttt 84300 tataggtttt tatagttaga gtattgggtt tttgttagag atgtagaaga gatgatgttt 84360 ttagttttta tgtggtttgg tttttattgt ggatgttggt gattttagtt ttttttttaa 84420 aattaagagg gttgatgttt tatattttag gtttttagaa agagttgtta tttatttata 84480 ttgttatatt ttttttttat ttttttgttt tggaaagagt agagtggata tgtgtttttg 84540 tagaaattta tttatagttt gattgtagat gtattttgtt tttttattga gtttttgttt 84600 tatgaagttt gttttgtttg tatttttttt tttttttttt tttttttttt tttttttttt 84660 tttttttttt gttttttttt tttttttttt ttttttgttt tatttttttt tttttttttt 84720 tttttttttt tttttttttt tttttttttt gtttttttta tttttttttt tttttttttt 84780 tttttttttt gaatagttaa agatagaatg aatggtatag gtaggtattg agttttttgt 84840 aattggaggt gtttaagtgt agggtggatg ggtatttata gggtaggtat tgaggaagga 84900 tttttttggg attgtggatg gtaggatagg ttttgtggag ttttttgagt gggtgtagaa 84960 gagggagggt atgtttttgt tttttgtttt ttttgggttg ttaggttgtt atttttaatt 85020 tttatttttt ttttttttat ttgttgggtt ttatgggatg ggtagaggta ttgttagaat 85080 atggagttgt ggtttataga gggttagtag ggaggagagt tttttgggga ttatgttgtt 85140 ttagttattg tggtgatttt gaaaataaat gttttttttt ttgtttgagt ttttgttgtt 85200 tttgttgatg tggaattagg gtaggttggt gatttagttt ttatttttgt attgtattgg 85260 tggtaagttg tttttagttt tagattttat agagtagggt gtttttttta gaaaaatagt 85320 agggaggtta ggatattaag ggttttaggg atagtttgtt ttttttggtt ggtatgagtt 85380 ttagttaagt tttttggtat tttgggggtg aggaggtatt agttgtgtgt tttagttatt 85440 ggttgttttg aggttgggtt ggtgttaggt tggttatttt tttttgtttt ttagtgtgat 85500 tttgtagagt ttttggaagg gttagagggt ttttttttat tattggtgtt tatgggatat 85560 tgtgttttta ttttattttt gtattttagt tttagatggg tgttaggaag ttggagattt 85620 tagttatttt atgattgtgt tttgtggggt tggagtagga ataggagtag gaggaatgtt 85680 ttggttatgg gattgtgtga agagagaagg attaggaaga aaatatgagt tattatgttt 85740 gggttatatt ttagtagagt tgttggtggt tttttaggta tttgaattta ttaattataa 85800 agtttattag gtgtgtaaat aaataaatgt tgtttaggag gtatagttag ggttttgttg 85860 gagagggatt attttggagg ggttatattt tttatttagt tttttagttt ttttgttttg 85920 tgtgtgtgta gtttttgatt attattattt ttgtttttgt tatttgtttt tagggtttta 85980 ttaggttgga tgttattgta ataaaatgta gtaatagaag gtttaggtag tgttgtagtt 86040 tttggtggta ttattagagt tagtaggtag tagggttggg gaattttaag ttgatttagt 86100 tttaagtgtt ggagtgggga gtttggatga ggtgggggtg gggaattggg gagttatgga 86160 gtagagtatt tgttgtgttg aaggttagga gtttttttgg gagattatga atttagaata 86220 ttaatatttt gtttaaaaag ttttttgttt tggagataag agtttaggtt gttgtggtta 86280 ggttttgttg taaatgtttt gtataaagta ggttgggggg attattggga agtttgggga 86340 atagattggt tatgtgtttt tttgagtgaa attttatggt tgtattgaag tggttaggta 86400 gagggtgtga tggggtgtgg tagttgtata ttggtttagt taggttgaat ggggaaatgt 86460 aaatttaggt ggtttgaaag agatttagtg gtttatagtt tggtggttgt ttttagtata 86520 ggtgatgtaa agagagaagg ggttttgggg gtttggttta ggtggaaatt atgtattgtt 86580 tgtgattttg ggtatgttga ggttggagta ggtttgtttg gtggttggta gaatgtatat 86640 gaagaattta tgtgtgtttt gaatgttttt tttgtttttt tgggtttatg ttttattagg 86700 agttttttga ttttgttatt ttgtaaagga aattgtgttt tgttattgta taggattgaa 86760 taggtgtgtg tggagttttt aaagttattg ttttaagggg ttttatggga taatgggaga 86820 gttgttgtga tgtttaagat taaagtgatg gttgggtgta gtggtttatg tttgtaattt 86880 tagtattttg ggaggttgag gaggatggat tatttgaggt taggagtttg agattatttt 86940 ggttaatatg gtgaaatttt atttttatta aaaaaataaa aattagttgg gtatggtagt 87000 gggtgtttgt aattttagtt atttgggagg ttgaggtagg agaattgttt tgatttggga 87060 ggtggaggtt gtagtgagtt gagattatgt tattatatta tagtttgggt gatagagtga 87120 gattgtttaa aataataata atgttaataa taaataaaat aataataata aaataataaa 87180 agtaaggatt tgaataaata tttgtatatt tatgtttgta gtagttttat ttttaattgt 87240 ttaaatgtgg aaggaatgga tatataaagt gtgtgtatat atagtggaat attatttagt 87300 ttttaaaagg aatggaattt tgttattata tgtgaatttt gaataatgaa ttttgaagat 87360 tttatgttat gtaagtttgt tttataagga taaatattgt atgattttat ttatgtgaag 87420 ttaaatttat agagaaattg gaatgatggt tgttagtagt taggggaagg aaggatgggg 87480 agttattgtt taatgaggat agagttttag tttgggaagt tggaagaagt tttggaggtg 87540 gatggtgttg atgggtgtat aatgtgaatg tatttaatgt tattaatatg gaaatttggt 87600 taaaatggta aatttgtttt ttttgttttt gttttttttt tttttgagat ggagttttgt 87660 tttgttgttt aggttggagt gtattggtgt gattttggtt tattgtaatt tttgtttttt 87720 aggtttaggt gatttttgtg ttttagtttt ttagagagtt gggattatag gtgtttgtta 87780 ttatgtttgg ttgatttttg tatttttagt agagataggg ttttattatg ttggttaggt 87840 tggttttgaa tttttgattt taggtgattt atttattttg gttttttaaa gtgttgggat 87900 tataggtgtg agttatggtg gttggttaaa aatggtaaat tttatattat atatatttta 87960 ttatagtaaa aatgtattgt tttattagaa aaatgataga tttttataat atgaattaaa 88020 ttataagtta tgaaggaaaa attaagtaaa atattaaaaa attatttata agtaattata 88080 tttaaaataa aagataataa atatataatt tttattattt tttaggtttt ttgtaatatt 88140 taattattgt ttgttttgtt gtggttatgt ttttgaggtt gtatttgtat gatagaaata 88200 ttatatttgt ggtgattaaa tatttttttt tagttttatt tttaatgatg ttatatagat 88260 aatttgaaat tggttggttg ggtatgatgg tttatgtttg taattttagt attttgggag 88320 gttaaggtag gtagattatt tgagtttaaa attagtttgg ttagtagggt gaatttttat 88380 ttttagtaaa aatataaaaa ttagttagga gtggtggtgg gtgtttgtaa tttgagttat 88440 ttgggaggtt gaggtaggag aattatttga atttgggagg tggagtttgt agtgagttag 88500 gattgtttta ttgtatttta gattgggtga tagagtgaga ttttgttaaa aaagaaaaga 88560 aaagaaagaa attggttaag gtaggaatat tgatattata ggaataggta agtgttataa 88620 attgggaaat tgagtgttgt tgtttttgtt ggttttaggt ggttggttgt tgattgttaa 88680 ttggtatatt attggaggag ggaggtttag attgatttgt agagagatta gaggtagaaa 88740 tgtattatgg tttggatgtt gagggtgagg gaaagagagg agttaatagt ggtgtttgga 88800 gatttggttt gagtaattag gtggatggta gtattgtttt ttaagatgag gggttgtggg 88860 aatttgaggg gttgtggaag gttttgttat tgatggattt agggtttggt agttttggga 88920 ggtttatttt gtgttaggtt atgtagagat aagattattt gggttttgtt tttgggaagt 88980 ttttgtttat gaggatatag tttgttattt aatggggtgt tttgtttgga gttttagtgt 89040 tgttgggaga aagtttttta tttttttttg ttttttgagt tttttttgtt tttttgttag 89100 ttgagttttt ttatggaggt tgtgtttgga ggggggttat ggatatggat gtgtgtgtta 89160 aatgttgttt ttttgtggat ttttttttta ttttgttttt atgttttgta agttttattt 89220 ttttggggtt tgatttgtgg ggtttttttt tagatttgtt tttttttatt tttagaaagg 89280 tgtgtagggg ttttttatgg tttttttttt tgtttttatt tttttttttt tgggatagtg 89340 atttgttgga tgggtgggtt atttataggg tttgtgattg tttagatatt tttgttgtat 89400 gaagttttga ttttaaggta tgatgtagat gggaataagg tatgagtttt ttttggttgt 89460 tgtaataatt gttgaaattg ggtggtttat agtaagggga atgtgttttt ttatagtttt 89520 ggaggttaga agtttgaaat taaggtgtta gtagggttag ttttttttga agattttagg 89580 ggaaaatttt tttttgtttt ttttagtttt tggtggtttt aggtgttttt tggtttgtgg 89640 ttgtattatt ttggtttttg tttttgtttt tataaggttt ttttttgtgt ttttgtattt 89700 ttttttttgt tttttagaag gatatagtat tgaatttagg gtttatttta ttttgagatt 89760 tttgtttaaa ttttttttgt agagattttt aaatagaatt aggttatatt tgaggtttta 89820 agtgggtata tttttgtttt gggggggatt attggtttat tgtaggtttt gttgtgtatt 89880 gaagatgtag gtggtttttt tggttaggtt tgtagttggt tttgtttttt tttgtgattg 89940 tggaagaatg tattttgttg gatgtatagg tttttatagt ttttttgttt ttgttaaatt 90000 ttagtttagt tttttttttg ttgttggtgt gtattttttt tgtttagtgt tttttttggg 90060 attgtgtgtt taggttttga ggttttagaa aaggggggtg gagggttttt ttattatttt 90120 gtagtaatga ggttttatta aaattttgga gttttagatt ggatttagtt tttagttatg 90180 attaaaggat agtttgggat atgattaaag ggttagagaa agatgattta ggttgagaaa 90240 gaggaggtta aggagtaatt ggattgtttt tgaatgtgga aaaggtaatt atgatttgaa 90300 gggtggtgtt tagttgtttt ttattttttt tgaggatagg aaaaaaaagg aaataaatga 90360 tgtataatta gagtagttgg ttagatatga gggtgaattt tttggttggg agtatggtta 90420 agttttgatt tgggtttttt gaaagagttt ggggaatttt tttatttgga ggtttttagg 90480 tttggttatg tggttttgag tgattatatt gaaggggtag tggttggggt tggagttggt 90540 gggttttgag tatagttatg aaggtatgtg tattttttgg ttgttttttt gttattgttt 90600 tttgggtttt tattttggtg aggtgtgtat tttggtggtg ttttttaggg aattaaatat 90660 gtttgttgta ttgtgtgtgg agatggagaa tgtataattg gttgattttg tgttaatttg 90720 gtggaatttt atgttagttt tgggaaagaa taattgtatg ggtgtgttta tatttattag 90780 gtgtttttta gaaaaatatt tgagaataat gttgtggttt aggatggttg ttgtgttgga 90840 tttggtattt ttttaggggg gttgtgttgt tgggttgagt tttttaggta ttggattttt 90900 aaatttttaa atatggtgtg gataggtggt ttagtagggg ttggattatt tgataggttt 90960 aggtgttgga gtttagataa gatatatttt ggtttggtgt ggaagatatg gggtgttatt 91020 aatggtagta atggttgtat ttttgaaatt tgggttttta ggttgatgag ggtgtgtatg 91080 tatttgaaat gtttgtggtt ttgtagtttt tatgtttata aatttatttg gttgaaaata 91140 gtttaaaata tttaaagtat gagggaggga gtgtttgttt tttttaaaaa ggaaggattt 91200 gattttattt atttaaaaag ttatttaaat ttagaatatt ttttgtaaga gattttttgt 91260 tttttgtttt tttagaatgg ttggagagtt ttagtatttt tgtatatttg ggatatttta 91320 gagggggtgg ggaggggtaa gtgggtagtg agtgatttta gatttaggat gagttgttag 91380 gtgttttttg gttatatatt taagggattg gagtgtagtt gtagtgttgt ggtttgttgt 91440 tttgggggtg ggggtgttgt tttatgttgt gaatttttat atggtttttg attttgggta 91500 gaggttgagg gtttaaggga tggggtgata gggagagtat gtaggagtgg gtttttggtt 91560 ttttagggtg agtggaagaa gtgttttttt tttttgtagg tgatagattt ggggggtttt 91620 ttttgaggat gagagtttgt tgttttttaa gttttgtgtt taatttaggt ttttaggttt 91680 attttagttt tttggttttg tttgttttgt ggatgatata gtttaagggt agagattgtt 91740 ggtttggagg gaaggttagg ttttaggtta gggtttagaa gggagggaga agtttttggg 91800 gtagtttttt ttttgtttat ttattgttta gttttttttt ttatattttt ttttggaaat 91860 gtttgttttt gataaggttt attttttgtt tttaggaggt ttttattgtg gaggaaggga 91920 ggtgttgttt gtttttggtt tttttgatag ttgtgtttta tttttgtttt gtgttttttt 91980 ttttggatag tgtttttttt agggtttatt taggagggtg tagtggtggt ttttggggtg 92040 gtggttgtgg tgggggtgtt agttgtaggg gtgtttttgg tgggtgggag ttggtggttt 92100 tttgttggtg ttatgggatt tgtatgtttg ttttgtgttt tttggttttt gagtttatag 92160 gttgggattt tgtttgttag ttgtgtgtgt tgttgtttaa tttttgtagg tgtagagtgt 92220 gtggtggtgg tgatagagaa ttttgtttgg ttgtttaaat atagtttttt gtagaaggat 92280 tttgtgtttg gggaagggga ggaatttttt tttttttggg tgtttgtttt ttttgttatg 92340 gtttggtttt tatatttgtt tatatttggt tgtagtgggg tgtttggggg gaggggttga 92400 ggttgtgttt tttgttgttt tttgggtgtg ggttaggtgg ggaggagggg ggtgttttgg 92460 ttgtgtgttt aggattgttt tttagtggtt atttgggttt tagtttttta ggtttggttt 92520 tgataggtgg gtggagtagt tagtgtgaga tagggaggtt ggtgtgggtg tgggaatttg 92580 atttgtttgg gaggtggggg tggggtgggg gtgtagtgtg tggggagggg ttggtgtttg 92640 tttttttttt ttatttattt agttgagtta gggggtttag gggttttttt ggtggttagt 92700 tttgtattgt aggagtgtgg gtgtggtgtt ttagttagtg tgtagggttt gggttttgtt 92760 gggggtgttt ttttgttgtt gttttttgtg tgatttgttg tttattagtt attatgttgg 92820 attttgtggt taatgtgtag ttggatggga ttattttgga ttttgaaggt gggtgttggg 92880 ttggttgttg tggttgtgga tgtgttggag aggattttgt gggtgggttt ggtgtgggat 92940 gggggtgtgt tgaggggaga tgggagtgtg ttgaggggag atgggatttt taatttaggt 93000 gtttttttgt tgagagtgtt gtgtgttttt ggttttgtgt ttgtgttgtt tatgtggggg 93060 attttgttag gggtatttgt gtagattttg tgtgttttta taggattttg tgtttgtttt 93120 gtgtattgtt gtttgggttt tttttttttt attgttgttt gtgtttgtta agtgatagtg 93180 atttttttga gggtttgtga ggttgttttg gaatttttta ggatgtatag ttttattttg 93240 ggaaatttat tggttttttt tttttggttt tttttggtgg tttttgggtt ttgtttggat 93300 ttggtaatgg gatagggagg ttgtttttta tttttgattg agtggatagt tgtgttttgt 93360 ttgggtggat agtttttttt ttttttatgt tagttttggg gttgttaagt tgtgtagttt 93420 gtgggttggg agtattgaat ggatatagtt taggttgtgg tagggtttag agtgggatgt 93480 tttatggttt ttatttaggt ttggggatat ttttatttgt tttttagaat tgggttgtgg 93540 gggatagaag gggtttgtgt gtgggtaggg agagtatttt ggtttttttt tgtttttggg 93600 gtttataaag tgtgttggga tttgtggggt tgttttgttt aagtttgggt ttggtgtttg 93660 tgtttttgag tttgtgagtg tgtgtgtttt tttgtgtttt tttgattgtt ggtgttgggg 93720 ttttgtgttt tgtgtttgtg ggagtaaata tagtaggtga aggggaagtt tatataatgg 93780 tttttagtgt tttggggtag ggtttttgag gggtgggttt gtttttgttg ggatttggag 93840 tttttgtttt ttggagaggt ttttaggttg atttgggtag agttttttgg tgggttggga 93900 gggggaaagg ttgtgttgaa atgagtaaat tgtttaggtg ttaggttaag ttgggaggtg 93960 attagtttga ggtttttttt gttttatggt tagaattagg gttgatattt gggtgttttg 94020 agtttagttg tttatatggt ttatttgggg ttagttttat ttgagtgggg gaggtggggt 94080 tttttggggg attagaattt tggttggatg ttaagtagag tgttagtggt tgttttttag 94140 ggttgggttt gaggagggtg tggggtggtg aagggatggg agggggttgt gatttagtgg 94200 ttattggtgt tgtgtagagt gtgagttgga aatattgtag ttattttgtt agtttagtgg 94260 tgaaagtttt tttttaggtt ttattttttt gtatttttgt tttttagagg gaggggaggt 94320 ttgggtttgt agagttggga gggtttgttg tttttgtttt ttttttttat aatatttttt 94380 tatttggata tttttgggta tatgtttata ttggggtttt tttaggttta ttgtgttttg 94440 ttgagttttt tgtagttttt gagtgaatgt gatttttttg tttttgtttt tttgtaattt 94500 ttttttgtga ttgttttttt aggggttttt tttgttttaa atgtttaagt ggtatgattt 94560 agttggtttg attatttttt agtaagtttt tatggagaga ggttttgtgt tgtgtagagt 94620 tttttttttg tttgtgggat tgaggttttt gtttttagtt tttaatagaa agtgttgggt 94680 ttttagtggg atttttgggg aagaattttt gtgttttaat gggagttttg tggtgggagg 94740 ggaggttagg gtttggggtt gtgtttgttg tatagttgtt attatttgta ttatgaaagt 94800 tgttagtgtt ttttttttgg gtttttgggt gtaattttat ttttgttttt atgtgttttt 94860 atttggagtt gtttttgtgg ttgtttttta agttagtttt gtgattttgt aatttagttt 94920 aagataatgg gtttattgag attattttgg tgtagtagtt ggtaattttt tggttttggg 94980 ggaaggtttt ttagttttgg ggagtggggt tttaatttgt tggttttttg tgtttattag 95040 tttttttttt gtgtgttttg aatggttttg ttgggaattt tggttttaga gttattaggt 95100 ggtttgagtt gataggtgtg agagagtgtg tgtgtgtatg agtgtgtatg tgtatggggg 95160 ttgatttggg gtatggaaag gtggtttttt ttggtgttta aggagtttgg agtatagttg 95220 gagggtgtgg gggtgtgtat atgggagttg gataattttg ggtggataga tagatgtggg 95280 gaagggatga ttgaaggagg tggaggagag agtgtgattt agtttagtta ggggtgatgt 95340 ggataggtag tttttgaatt agggtagaga aaagttatta ttagttagta ggggagaagt 95400 tagtatggag gaggtggatt ttgagggaga gtaggaattg gattgtaaga ggaaggagag 95460 ttttttggtt agtagtagtt agtagtagtg ggggaggttg gaatgagttg gttggagagg 95520 gggttggggt ataaggaggg gtttgtttgt gaagattata tgggttaggt tgtggagggt 95580 taggtatgtt tgttgggagt gtagttggtt tatgggaagt atttggagtg gttgggaatg 95640 ggtgtaggag tagtgttgtg ggagtatagg tttttttttt ggggtggttt atttggtgtt 95700 ttggtttttg taaggtaggt tgaaagggtg gggaggaaat tgttagtttt ttatagtgtt 95760 gggatggtgg ttttagggtt tttgaggtta gtggatgtgg gtgtttgtta ttatgtgggt 95820 tgttgagggg tggagatttt aggggttatt ttaaagtagg atgagttttg agttatggta 95880 tttttggggg tagtttttta attgagtaga tgtttaggtt tggaattttg taatagaggt 95940 tatagggttt tgattagggt gttttgggag gtttagaatt agtggtagta tatagggtag 96000 atggtaagtg atttggtatg gggaaagagg taggtgttta ggttggtata gtatatttgt 96060 aaggaatagg tagatgggaa gttgtttgtg ggtttgtgtg tgtgtttgga gttaaaattt 96120 tgttaatgtt ttatgttttg ggtatattta tttttttttt ggggagtatt ttttttttta 96180 tttttttttt ttttgtttgt tttttttatt tagggttttt tttatttttt ttgttttggg 96240 gattgagggt attatggttt tatgttttat tattgatgag ttgtataggg atttagtttt 96300 tttgttgttt aggttgggtt ttttaggttt agggttttta ggaatggaga gggtattagt 96360 gttttttatg gatttaaatt ttttgtattt tgtttttgtt ttttttttaa gataggtttt 96420 tgagttttaa ggttttaggg ttttgtggag gttgttatgt agtagtaagg agaatgtttt 96480 gtatttggtt gatgagattt ttagagtttt attttttatt tttttattgt ataaatgggt 96540 ttttaggtga ttgtagtatt tgttattgtt tgtaataggg tgataagagg gatgattttt 96600 tttttttttt tttttttggt tggtggaggt atggggttgg tggatggtat gtgtttttgt 96660 gaatttaggt taaatttgtt attgtaaata tgattataat ttgggttttt gtgtaataaa 96720 agttttttta agtattagtt gttggtttgt tttgtttagt ggtgtttgtt gtaattagat 96780 ttgtatattg agaaagaatt taaaagtttt tgatgtttgt tgaaataatt tggtttagga 96840 tttatgtgtt tagattttag agttgtgtgg tatttgagtt ttttttgagt ttttattgtt 96900 gtttgaggag gatttttaga tttgtgtttt ggaggtagag taggttgtgg gatgggtttt 96960 tgggtgggaa ggattatgtg gatatgtttt tttgtttgag agttttaata tttttgggat 97020 gtgggagttg gtgtgttggt aggatttagg tgtttttttt ttttttagag aaaaaggttt 97080 tgttgtttgg taataggtgt agatttgttt ttaattaatg ttagtaggtt ttttgtgtga 97140 tgaattttgt tttttagtta agatttaagg tattttgtga atattgtttt tttgtagttt 97200 gagtttttgt ggtgggaggt aggagttatg gggagtgggg gtaggttttt tatatgggtt 97260 ttatagttat tggtagtatt gatttgatgt tttttgagtt tagagtttag ggttagatag 97320 atttattgtt ttgattatga gttggtttat ttagaggggg gtggatatag tatttaggta 97380 gtagatgtat tgtgattagt tttgtagtgg ggttgtgggt tttttgggtt ggatgtttgg 97440 gaagaggtag gtggaggtaa atgttaggat atttttgtag tgattgggtg attgtaggtt 97500 ggaaatgttt tttgtgggtt gtggttgttt aggaaggttt tgaatggggt tagtggatag 97560 agtttgtatt tagaggggta gtgttttgga ggagtgaggg gtatggtagt gtagggatgt 97620 ttaggttgtt tttattttgt tattggaaag ttgggtggtt ttggtttttt tagttttttt 97680 gtttgttttt ttgtttgtaa agtggggtta gaaatagttt tttttgaggg ttgttggggg 97740 attttgagat gtagtttatg gtgttgagta tgggttttgt tttttatggg tgtggtgggt 97800 gttgtggttg gtgtggtatt tgggtgggaa aagggggtat ttgtaaagga taggtaggtt 97860 tggatgttta aatatgtaga tttggggatg ggaggtttta ggtaagggtt tgtgtgatgt 97920 tattgtatga atgaggttgg atagtatggt tattattaat tatggaaagt atggtagata 97980 ttagtgttag tagtgtttgt ttgggggttt ttttgagttt gataggtatt taggttttta 98040 gtgtagttat gggatttttt tttttttgtt tggttgatat tttggaggtt ggtgttatgt 98100 tggttgtagg ttttttttat tgggaggttg ttttggtttt ttttgttatt atttattttt 98160 atttttattt tggagtgtta tagatgggtg gattatatgt ttatttgtag ggttaagtgt 98220 tgataatgag gtgagtattt gttggatgat tggattatga ggatagtggg ggtgttggta 98280 gtttgtgttt ggttttgtag gttggttttt ttttgaaaag tggttgtggt agagtgtgta 98340 ttttagggag tggtgtttgt tgttttgaat atttttattt agtaggtttt tgtaagggtt 98400 tagttaagtg tggtgtagag ttgggttggt agttggaata gttttatttt gtttagtggt 98460 gagattaagg gttgatgggt taaggttgtg tgttgtttgt ttagtttgtg gatttattta 98520 ttgagtattt ttatattttt atattgggtt tggggtgtta ggaggtggag gggggattgg 98580 gtgtttggaa aaataagttt attgagagtt tgagttttta ggggttagta ttaggtagtt 98640 attatggtgt ttggtatata gtggttattt ggttttgttg gttgttttgg tggtggagag 98700 tgtgtatggt ggttgtatgt gatgggtatt atttagggta atatagatat gtagattgtg 98760 tatttgtttg taggagttag ggatttttta gtttggtaat ttgtgatttt tgtttatttg 98820 ttgggagaga ggtgttgttt tttgatagtt tggtgttggg agagtagaat tagggttttt 98880 tttttttttt tttatttttt attttttata tgtttaggta ttaggggagg ttatatttag 98940 ggatgagttt tggttattgg gtttagggtt ttattgttgt tatttttttt ttttgttagt 99000 tagttaaatg tttgtttatt attgtgttgg ggatggggtt ggtttgtttt tttgaagttt 99060 ttttggtgta tagtttaggt tggagttttg gatgattttg ttattttttt ttttgatttt 99120 ttttttttat tttgatttat tttagaaatt tagttaaaaa ttaagttttt gtgttttttt 99180 ttgataaagt tattgaggaa aaatggttaa atattgtttt tttttttaaa gtttttttgg 99240 ttttttttaa atttggaggt tttgagttgt ttatgagatt aaagggtttg gaattttttg 99300 gaatatagtt ttagaagtgg gaggatttgt tattttttta gttaaataga tttattagtt 99360 ggtttttaga tatttttagg tgtttggggt atttttgggt ttaggttgtt taatttggtt 99420 tgtagagttt tgaggttttg tttagattgg gttagtagat agttttagag attttaagtt 99480 tgttgttgtt tttaaaagtt ttgttaatgt ttagaaattt agagggataa gaagatgatt 99540 ttgatgttag ttgggattat aaatagtgag gtttgttttt ttttttattt atgtttgttt 99600 ttattgtttt tgtagttggg tttttagggg attgtttgtg gttatggggg aggttgggaa 99660 tgtggggttt agattttatt gggttttttg tatttttttg tttttttttg tttatttttt 99720 tttttggaaa tttttgaata tttttttata gtttttggta ttttgttatt tttggtattt 99780 ttgggttaat tgggaaagtt attatttgtt taatatttag aaaattaagg ggtttggttt 99840 taaatatatt gtagtgtttt tttttttata tggtattgaa ttttttgtgt ttttaaagtt 99900 aggagtttgt gttttggatg tgggtgatgg agttttgtag atatttggag tggttttttt 99960 gggagagttt tttttgtttt tttatttatt tgtttttttt tttttgtttt aagttttggt 100020 tatagttttg gaggggttat ttgagtgtag gttgttttta ggtgtatagt tggagggggg 100080 tagttatttt atattttttt gtttgttagg ggtattttta gggatttagg ttttgaggga 100140 tagtggaagg gtggggtggg gagtaggttg ttgttttgtg ttatttgggt gttatgtaga 100200 ttttgaatgg gtagtttttg ggagttggtt tttttttttt atttttttta tagtgttgtt 100260 tttttgaggg gttggagttt tttggagttt tttgtagttt gtggtaggtt tttttgattt 100320 tgtgtttggt tttgtagttt ttaatttata gttagtggta tgaagaatat ttttggttgt 100380 ttttatttgt ggtttttgta ggtagtagtt ttttggggta gggtttgggg gttttggtat 100440 ttttttgtgg gattttttgg gtatgaggga gggagttatt tgggttatag atagattttt 100500 tttttgtatt taggaggttt aggatggatt tgttttattt ttttttttgg tgggaagaga 100560 gtatttttgg ttatggggaa tgtggtttgg atagagttat ttagtttttt ttttttttta 100620 ggtagggttt tgaaagatgg agatggtttt gtttttgtta ggttaatagt tagtagtttg 100680 gtggattttt atgtagttta ggtaggattt ttttttgttt ttatttttta ttttatgtgt 100740 aggaagttgg ttttaagtag ggatttttgg ttttgttttt tatgtgggtg ggtagttttt 100800 ttgtgagggg taggttaggt ttttgtttta tgttttttag agattgatgt tatttatagt 100860 aagagtatat aagttttttt ggttttaaat taggtttgga ggggtggttt ttttttttgt 100920 tttttgtttt ttgtttttta ttaaaggtta gggaatggag tgttttgtat gtttgttggg 100980 gttgggtttt tttttttggt ttaaaatgaa gggttggaat ttttggtgta gattgtatgg 101040 tgagaggtgt tttttgggat ttatttgagg agtattattg ttgaatgttt tgttaggtta 101100 ggagtattgt tgggggtggg agaggtagtt ggtttatttg tttatttaat agttatttat 101160 gggtatttta agggttagtt ttgttttagg tattgggggt ttaggtatgg gtttaggaga 101220 aggggtagaa tgggagggtt ttttggagga aggtttttta attagagatt ggggtaggag 101280 tttgttaggt aggtgatgtt ggttagtttt ttttgttatt tttttttttt tttttttttt 101340 tttttttttt tttttttttt gagatagagt tttgtttttg ttgtttaggt tgtagtgtag 101400 tggtgtgatt ttggtttatt gtattttttg ttttttgggt ttaagtgatt tttttgtttt 101460 agttttttga gtagttgaga ttttaggtat gtattattat gtttagttaa ttttttgtat 101520 ttttagtaga gataaggttt tattttgttg gttaggttgg ttttaaattt tttattttag 101580 gtgatttgtt tattttggtt ttttaaagtg ttgggattat aggtgtgagt tattgtgttt 101640 ggtttttttt tgttattttt gtagatttat agtgtgtgtg gaagattgta tgtttgtgtt 101700 tggtatagtt gtttttggta tttaggtggg aggtggggga gagggttgtt ggtgttagta 101760 taggttatgg tatgagatag gtttttgtag ttaagtgggg tgtattgtag tattggaggg 101820 gttttgttgt gtatgagatt taggttttgt atttgttttt ttttttagga ggtttggagg 101880 gttgggaggg attagggtgg tgaaataatt taggtgggag agaggtattg ttggagaggt 101940 agagggagtt gtaggtttgt agtagtgagt tttaaatttt gggtttttat tagaaaattt 102000 tagaaagggt tgttttgttt ttttttttaa attataaaag aaatttttgg ttgtttgggt 102060 tttttggggt tgggtggggg aggagatttt ttatttgtat ttttgtaggt ttagtattgt 102120 gtagagggag gagggtggag gtaaaggtga gggaggaggg tggaagtaaa ggtggggttt 102180 ttttttagtt ttgttgtttt gtttggttgt tgtttttaga tttttatttt tggtttggaa 102240 atatggaatt ttgggatagt tggggtaggg ggtatagaat ggagattttg gtgagggagg 102300 aatttttttt ttagttttgg ttgtggttat agtaaggtta ggttgggagg attttattta 102360 aatatttata ttttttttaa tatttaaatg atgaagtagg tttttgtata tagttgtttt 102420 ggagttagtt gttgtttgtt ttattttttt tttttttttt tttttttttt tttttttttt 102480 tttttttttt tttttttttt tttttttttt ttttttttgt attttttgtt tttgatttaa 102540 gtttaggttt ttttagttgt ttttttttta tttataggta ttttttgtga ttgagttttt 102600 ttttgttatt ttttataatt atttttttta attgagtatt ttttaggtgt taggttttgg 102660 gttggtattt tgtatataag gtgtttttta atttttatga gagtttaata aggtagattg 102720 ggttgttgag gttttagtgt tggaaggttg gtttgggttt ttttagtttg tatttgtatt 102780 tatttattat ttttttattg tggagatttg ttttttggtt tttggttgag tatgatggaa 102840 atttttgttt attagttttt ggagagtggg gatggttgag ggttttgatt ttggggtttg 102900 atgggggttg tttttgtttt attttagttt ggttgttttt ttatttaatg attgagtttg 102960 taaaattaga ataatagtgt tatttggttg gtattttggg tggttgggag gtgtgggaga 103020 gggtgtatgg aggggttgag tgaggtgtta gtattgtggg gatttttgag ggtagttttt 103080 ttaggtttag ggtggagtgt aggtagaggg tgtgatggtt tagtgtgttg gtttatattt 103140 ggttttgttt ttgtttatat ggtaatgtgg gggagttatt agttttttag tgttttagtt 103200 ttttatttgt gtaatgggga taagagtaaa ttattgtttt taggtatggt aagtatttat 103260 atatattgat tattgtagaa tgaatatagt gagttttttt taggttttta ttatatgtta 103320 ggtagggtgt taggttttag tggagagggg ataatgatgg gtaagttggt ttttgttttt 103380 aagggttgtt gagtagggag gaaggtggtg gttgttttga ttgtgatttg gagtggggtg 103440 atttgtaaag aggttggtgg gaggttggtt gggggttggt tgggggttgt tttttttttt 103500 gtttgtgttt tgtggtaggg tattaaattg gtttttttta tggatttttg aggttttgat 103560 tgtgggattt tgggtaggtt ttgggatttt gtgattttgt ttttgtttgt tatttaggtt 103620 tttgttttta gtagtgttta gtatatggtg atttttgtat gttttttagt gtgtgattga 103680 ttttggagtt gagatttggt agttgaggtt ggatattgtt tttggataat ttttggggag 103740 gtgggggtag ggtggggttg tgagttggta attttgagtt tttagtagtt tttgaatgga 103800 ggtttttttt ttgtaggatt tttggggagg aaggagggga tgggggagat gaggtttgtg 103860 agtttttagg agggtagagg tttatatttg tagtgtttta gaaatatttt ggggtgttta 103920 ggtttattta gtttttttga gttagaatta ttaagagttg gggattagta gtttattttt 103980 tagtaagatt tagaaatgat ttttttgaat agtttgagtt aagaatgata tatttggaat 104040 tagaatatta gaattataga ggaattgaga gaatgggttt aaaatgtgta gggattttag 104100 ttatatggtg ttatatggag gaaagtattt aatattatta ttgtatgaat ttgtttaaat 104160 atatatatat atatatatat atatatatat atatatatat atatttttta gtaaagagtg 104220 gaaagatatt tgttagaata ttgatggaag ttatttgggt tgtgggttta tagatttttt 104280 ttttttgttt ttgtgtattt tgtaaatttt tggttttgtg tttaaatttt ttttatagtt 104340 aggaataaag taatagatgt tattttttaa agtttatggg tttgtgtttg taattttaat 104400 attttgggag gttgaggtag gaggattttt taagtttagg agtttgagat tagtttgggt 104460 aatataggga gatttttatt tttttttttt tttttttttg atagagtttt attgtgtttt 104520 aggttgaagt ggtggtggta tgtttttggt ttattgtaat ttttgttttt taggtttagg 104580 tgatttttat gttttagttt tttgagtagt tggattatag atatttatat ttgtaggatt 104640 tgagaatttt ataagaggaa agtttttatt tggaggttgt tggggatttg gagttgttag 104700 tttatatatt ttttagtaga gatagggttt tattatgttg attaggttgg ttttaaattt 104760 ttgtttttaa gtgatttatt tattttggtt ttttaaggtt ttaggattat aggtgtgagt 104820 tattgtgttt ggttatggga gatttttttt taaaataaga ataaaaataa aaataaataa 104880 aagtttattg ttaaaaagaa aaatatatta tttaatttaa ttttttttta ggattgagag 104940 atgaggaagt agaggttgga aagtgttata ttttttggtt gttggtagtt aggggatttg 105000 aggtttgggt tggttttttt gtgttttagg tttggggtgt taggtggagt ttttgttttg 105060 tttaaaggtt taggtgtttt tgttagtatt gtttgttttt gtatttttgg ttataaggaa 105120 tgtgggttaa aggtagggtt tttgattttt gtttaggagg gtgaagtggg ttggtttttt 105180 ttgtttttgt tttaaggttt ttgtggttgt gtttttggaa attgttggtt tgagttagtg 105240 tgtggagttg ggatagattt tattgtggtt tttgtggggt tattttatgt ttgggttgga 105300 agggattttt tggtttagtt ttttttgttt tttattagga aattgagatt agagaggtta 105360 tttgtttggt ttggggtggg gtgtagatgg tgtttgtgat ttttgtatgt tatgtgtaga 105420 tagtttttta gttgtgggtt ttttatgtaa gtagttatgt tggggataat ttggttgaaa 105480 tttgtgattt aatgaagaga agaatgattt tttttgtagt tttgtgtttt ataggttttt 105540 ttttgttttt attttttttg tagaggggtt ttatgttggt gggtgggttt ttgttgttgt 105600 aatgggttta ggtagttttt gggtagtgga ggtttggttg tttttttgtt taatgttttt 105660 tgtagtttat gttgtttggg aagggtgggg aagtatttag ttattgggga ttttataaga 105720 tgggtatttg ggagatgttg attggtaggt taggtttttg tggtttatag gtaggttaga 105780 ggttatagtg ttgagttggg ttgagttggt agtttagggt agtgggggtg ggggtatttt 105840 gtttagttat gggttttttt ggtataaggg tttggagttt attgtaaata atttttttag 105900 tttttttttt ttttataggt tattagtaga attgaggggt tttttgttga tgaggtgtgg 105960 tttgggaggg gttagttgtt tgtttatttg atttttgtgg ataggtgatt ataggttttt 106020 tgttttaggg ggttggggga aagattgggg aggttttttt ggttttttta tttggaagga 106080 aaatatgggt ataggggaga tattttatag ggatatattt tagttagtat tttttggttg 106140 tgttgggggt atagtgtttg ttttgtttat aagaggggtt agtttttttt aggatttaat 106200 tttagttttt agtgtagggt agatgagtat ttagaggttt agaggattta tattatgaga 106260 gagaagttgt gattatatag gtattgaagg ttaagtagaa gagtgggata tatgggtgat 106320 ttgaaagttt tagggttagt gtggttagtt ttagatagtt ggggagtttt gggtattagg 106380 tttagtaggg gaggagggtt tttgtgatag tttgttgggg ttgttgtaat aaagttttat 106440 gaattttggg ggttgaagat ggttttagag gttagaagtt taaaattaag gtgttgatta 106500 ggttgatttt ttggggtttt tgtgggaggt tttggtttag gttttttttt tagtttttgg 106560 tggtttttgg gtgtttttgg gtatgtagat gtgttatgtt attttttgtt ttgtttttat 106620 atggtttttt ttttgtgttt ttgtgttttg taaggatgtt tgttattgta tttagagttt 106680 attttaaatt taggatattt tttttttgag attttttatt gtatttgtaa agattttatt 106740 ttaatttttg ttatatttat aggtttgagg gttagggttt tggtatgttt tttgggggtt 106800 attatttagt ttattgtggt agttgatttt aggggaagta gaatgtttta agtttggggt 106860 gagtggaggg aatgttgttg ggtggggagt gggagattag gtttggagat attgtggatt 106920 ttttttgttt gatgagggtg tgatgaggtt tttattttag gttttttgaa tggtggttgt 106980 ttttgaggag attttttttt ttggatttgt ttttttagaa atttttattt aggtttaggt 107040 tttaaggtgg atggtaagag gtggttgttt ttgttatatt tgatgggtga gtgtgtgaat 107100 ggggttggga gtaggatatt tgttattttt gtggatagat tttagaggtt tatgaatttg 107160 ttgttgggga aggtgtttga tttagtttga ttttttattt ttattttttt ttttttgttt 107220 ttttttatta gttttgtttt tagagtttta tttttttaaa ggtaggtgtt gttttttgga 107280 ttttttagta gttatttttt attttagatt ttttttttgt aggttttttt ggttttagtg 107340 tttatttttt tttgggtttt tgttttttta ttgtgaggtt tttgggtaga agtgtggggt 107400 ttttttgttg tgtttggttt ttgtggtata ttaggggttt ttttaggggt ttgttttgtt 107460 tgttaggttt ttagggagtt ttttaagttt ttagatgggt ttgatggagt tttttaatgt 107520 gttgttttag agtaggaggg gttttggttg agtttgagag tttttttagt tatattttgg 107580 gttgtttggg gtagttaggt agtttgtttt ttggaggtgt tgtttttttt tggttatttt 107640 ttttggaatt ttttgtgttt agttgtggtt ttttttatat agtatattta ttattttttt 107700 ttatttgtga tttttttttg ttaatttttt tatgtttttg agaatggaga ttaggttttt 107760 tttattttgg agtttagtag aatttaaatt aggtagattt gtgtaggttt atgtgggggt 107820 tttgtggtta ttgtggtttt gttgttattt ttagtttagt ttggtgtgtt ttggattatg 107880 ttatttagtg ttggtttttt aaattttttt tttggttttg taggtttggg aagtagttgg 107940 tttttgggtg tagttgtgat tggagtttga attttgtttt ttggggttat tgttttttgt 108000 aattaggttg tagtttatat tggtttgggt agaggttatt ggttgtttgt tttggggtta 108060 taatatagag agttttgtga ttaatggagg ttttatttgg gttaagtggt ttttggtgtt 108120 aggtgttttt tttttttttt tttttttttt gtatttttta agtgtttgta atattttttt 108180 taatggataa tgagatgagg agggagggag gggtggtttt tttgtttagg tagattagga 108240 atggttattg tttgtgtgtg tagtgatagg tttgggaata gataagggag agtttgtttg 108300 ggaggttgga tttttatatt gatgttgttt gtgtttggta gttttgtttt gggttttaga 108360 atagatattg attaatatgt tttttagggt ttttaggttt gggttttggt ttttggtaga 108420 gttttttatt tatgggaaga agtattgagt agttttgttg gttttttgta gggagttggg 108480 atgtattttt aagagtagta tgtgtgaagt ttggggtttg ggtaaaggag tgtttgggga 108540 agagtttgtt gttgttggag ggttggaagt agaggggaag gaggggtatg tggtaggttg 108600 aggaggtggt tggtgatttt gtggtgggga tgagggggtt atgagtagat taggagttag 108660 tattatgttt ttttgttttt agaattgagg atggagagtt gttagagagg ttttggtggg 108720 gtgtttgggg ttatttaaag ggtgtgggtg gattaaagtt gaggaaagtt ttattttggg 108780 ggattttgta tttaattttt gaggttttta gagttgtagt ttgtggtttt ttgaagttaa 108840 ttatttttta gggttttgtt tttgttttta gtgatagtta tttattaggg agtttttgat 108900 ttaaggagat ttgaaaggtt atttggtttt ttttttattt ttaggtaggt tatatttaga 108960 tttttttata tagatttgtt ttattttttt gttgtttttt attagggatg gagggtgggt 109020 ggttttttta tttaggtttt ggtggtttta ttttagttag gaaatttttt ttttttattt 109080 gttttatatt tttttttttg tggtttttgt ttattttttt ttaatttgtt tttagtggag 109140 tagttagtag ttggtttaga atttgggggt ggggggagtg ttagattagt gtagtatatt 109200 tgagagtgtg ttagaggtgt ttttattttt atagttgatt tagtaaagaa aagaggaagt 109260 ttagtaattt agtgttattt taaagtttgt ttggaatgat tttgtggttg ttggaattag 109320 gggtatgtgg tagatgatgg gagtaggtat agagaggttt ttgttttgga ttagttgttg 109380 ttgttttttt ggaggttggg ttgtttttta agaagaggat ttaaggtttt gtgagtggtg 109440 gttttttttg gagtttttat tgtggttttg gttttgtttt gtgtaaagag agatggtttg 109500 aagtagaagt tgttatgtgg ttgttttagg taggtgtttg tagttttagt tatttgggag 109560 gtggaggtag gagaatggta tgaatttggg aggtggagtt tgtagtgagt agagatggta 109620 ttattgtatt gtagtttggg tgatagagta agattttgtt ttaaaaaaaa aaaaaaaaaa 109680 aaggagtaga gaaatttttt ttagaaggtt tgtagttatt ttttttttat gttttagagg 109740 taaaaaaaaa aaaaattgta tattttgttt tttttttttt tttttgagat ggagttttgt 109800 tttgttgttt aggttggagt gtagtggtgt gattttggtt tgttgtaagt tttgtttttt 109860 gggtttatgt tatttttttg ttttagtttt ttgagtagtt gggattatag gtgtttgtta 109920 ttatgtttgg ttaatttttt gtgtttttag tagagatggg gttttattgt gttagttagg 109980 atggttttga ttttttgatt ttgtgatttg tttgtttttg ttttttaaag tgttgggatt 110040 ataggtgtga gttgttgtgt ttggttatat gtttttgttt ttgaataggt ggttttttga 110100 ttttgggtgt ggttatttta agattttgtt ttggtggggt ataattttgg ttttaggtag 110160 ggtgattgta taatttattg ttttttgggg gatatgttag tgaaagggat ttttgaatga 110220 ttatggtggg ataatagatg tgagttgggt ttgttttagg aaggttggat gtatgggttt 110280 tttgagttag aggagataat agtagaaagt tttgtggttg atgggattga gtaggagaag 110340 ggttggtgga ggttggggta ataatgtatt tgtttattgt gaagggtttg tgtgagttga 110400 tggttgatga gagggtagtg gggtgaggtt gttttttgtt aggttagatt agttttagga 110460 tatttatatt ttttttttag aattggtgat ttagtggtta gaaggggttt tagaattgat 110520 gggatattga gggagttgaa tggaatggtt ggagtggtta tagtaggttt taggtttttt 110580 tttgtttttt ttttgtgttt tgtttttggg gtttatattt tggggttgtt gtaatagagt 110640 gttataattt gggggtttat aaatatagtt tttggtggtt tttggagatt tttggtgttt 110700 tttggtttgt agatgtatta ttattatttt tgatttttgg tttttgtttt tatgtggttt 110760 tttttttttg tttgtgtgtt tttttttttt tttgtttttt ataaagatgt ttattattgg 110820 atttagggtt tattaaattt agaatgattt tattttgaga tttttatttt aattatattt 110880 gtaaagattt gttttttaaa tgtgattatg tttgtaggtt ttaggagtta ggatttaaga 110940 tatattgttt tgggggatat tgttgaattt attatattta ataaatttag agttggtgtt 111000 aatgtttttt gtggatatta tagtagattt tggaggtttt ttgtaaagga atttgtagga 111060 tttttttttt tttttggagg gatgagattg tagttgggtt ggggaaagtt gttggtttaa 111120 gttggggttg gtttagttgg tgttggtttg ttaggttgtt agagagtttt atttagggag 111180 aaattaatat tataaagttg ggggataaga gaaggtttgg aattttaagg gttggttgtt 111240 gaggttagtt gtttattttt ttgtgtttta ttttataggg atttaggttt gttagtgttt 111300 tgtttttgga aggaatgttg tgggttgttg tgttttatag gtagggtgga gggttttttt 111360 gtagttagtg agttgttttt tttgtagtgt gtagagggaa ggaggaggtt tgtttatttt 111420 ttttggtttt agttgaaaat ttaattatag gttttggtat taggtagatt tgtttatttt 111480 tatattatta ttgtagagtg agttaggttt tttgggtggg gttgtgatga gtaggaagga 111540 tttttggagt gtttgggatt ttttgggttt agggttgtta gaggtagaga gaaagaagtt 111600 tttttttaat atttgagtaa agatagttat tagaatttat tagagtggtt ttttgtggtt 111660 tttttttggg tgttgatttt tttggtgtat ttgaagtttt tagggatatt attgatgttt 111720 tttgtatttt tatttagggg ttagtggaaa tggttttttt tttttttgtt tagaggtatt 111780 gtggatgatg attttaggtt ttagatttta gttattgggt tatgtgtgta gataagtttg 111840 ggtagttagt aatttttggt tattaagttg gttttttgtg gattgggttg gtattggagg 111900 tgggttttag ttgttagtat tgtggtttag ttaggtttgg ttttgggaag gtagaggggg 111960 aggggattgg gaaagggatt gagttggggg tggggtggta ttttggtttt ttttttttag 112020 atttttggta ggtttgaatt atttggttgt ggttttttaa ggagggagtg ttttttttgt 112080 tttgatgtgg attttgtttt ttgtttatgt tgtttttgtt tttaaataaa tgtggttttt 112140 tgtggggagt ttgggggttg ttttttattg atattgttgt tttttggttt ttttttgtag 112200 gttttgttta gttttattgt gtttattttt aagttttttt ttttggatgg ttttgttttt 112260 tgagaatata ttttttttta ttattttaat tgtgtttttt tttttatttg gagtttgttt 112320 tatttgtttt aggagttatt tttttttttt attaagtagt ttaggttaat tttggagggt 112380 taatttgtgt ttttttagaa gtaggttttg agatagggat tttagtggga ggggatatta 112440 ggggatgttt gagtgtggga atgggttagg tagggaattt agttaataaa gggtgtttta 112500 ttagtttatt gtgattatag gtggttgttt agtttttata ttgggtagta tggggagatt 112560 gtagattgtg tttttagttt tgttttattt ggggttgggt aagggagttg gggtttttat 112620 attttagttt ttggttaagg attgtattgt ttattttttt tagttttttg agggtttggg 112680 tattaggaaa ggttttgggt ggagatatgg aaataggtta tgtgaagtta gtgggtgtga 112740 ttggtagtag taaggttagg atagttttgg ttattagtaa ggtgattata tattttagta 112800 tgtatagttt ttatagatat atatttagga gatggtaatt atattagtaa tagttatttt 112860 tgttgtgtgt tatgtttgta tttagggaat tttatttttt atttatttat ttatttttat 112920 ttgagatgga gttgtgtttt tgttgtttag gatagagtgt aatggtataa ttttggttta 112980 ttataatttt tgttttttgg gtttaagtta ttttgtttta gttttttgag tagttgggat 113040 tataggtatg tattattatg tttgattatt tttgtatttt tagtagagat ggggtttttt 113100 tattttggtt aggttggttt tgaatttttg attttaggtg atttatttat tttagttttt 113160 taaagtgtta ggattatagg tatgagttat tgtgtttggt tttaggggta ttttattatt 113220 ttattatttt ttatagtagg tgatattgag gatattgagg tttagagtag attgtggtta 113280 tgttattttt ttgtttggtt tttttgtttt tagttttgaa ataaagagta tggtttttgt 113340 gtaggtttat atgttttgtt tttagttttg gagtagtttt taagtttttt gaaggtatat 113400 taggtttttg ggttttgttt tttaagtttt ggataaatag gaggtgaagg agtttttgta 113460 attggatttt attttgttag tgttaaggtt ttgtttgatt atttatttta ttttatatag 113520 attagggatt tgtgttaagg tttagtgtta taggagagtg aagataagga ggtgtttatg 113580 gtgtatatgt tgttggattt attttgtaga ttttaagggt tatggggagt tatttgttag 113640 gtgaggtttt tttgtggttt ttttttgtag gtttagggta gtatataggg aggtgttttt 113700 ttattttttg gtattatttg tttggttttt ttgagttttg attttggttt ttagatagtt 113760 agtgtttttt tagggataga atttgttttg ttgttgttta gaggagattt agtttgatta 113820 gggttagtgt ttttggaatt tgagtttgga attttatttt gttttgggta gaggttatgt 113880 tgtttttttt tatgagagtt gagttgtgta tgagattatt ttgattttgg gttttattat 113940 ttttttgtat gatatttgtt ttaggttgga gtagggtttt gtggtttgtt tggtgttttt 114000 tttttagatt gaggtttgat atgtatatta ggaagtgttt gatttggttt taggagttgg 114060 gagtggtttg ttaggtagtt tgtggttaga gtaggggttt taataatggt tttttgtgtg 114120 gtatattttt ttttaaatag gtttaggttt aggttgtttt tgttttgatt ttgttatggg 114180 tttggagggg aaagtttgta tttggagggt ggtttattgt ggtttttttt tgtgtagtag 114240 ttgagattgt aggtgtttga gaataggaga agttttgtgt ttattttggg ttgtgagatg 114300 tttttttaga ggtggggatg gggatgggtt agtatgtagt tatttatatt ttttagtttg 114360 ttggtattaa ggtttgtgta tgtgtgtgtt tttttttttt taattttgtt tttttaatat 114420 ggagttttgt tatttgttta ggttggtttt ggatttttgg tttaagtgat tttttagttt 114480 taggttttta aagtgttggg attataggtg tgagttatta tgtttagtta gtattaaggt 114540 gtgtttttta agagtaatat tggttgggtg tagtggttta tgtttgtaat tgtagtattt 114600 tgggaggttg aggtaggtgg attatgaggt tagtagattg agattatttt ggttaatatg 114660 gtgaaattgt gtttttatta aaaatataaa aaaattagtt agatgtggtg gttgggtatt 114720 tgtagtttta gttatttggg aggttgaggt aggagaatgg tgtgaatttg ggaggtggag 114780 tttgtggtga gttgagattg tgttattgta ttttagtttg ggtgatagag tgagattgtt 114840 ttaaaaaaaa aaaaaaaaaa gaataatatt gatggtttta ttttttgaat atgttaagtg 114900 atttttatgt agtataagta ttttagaagg taggaaaatg taatgaataa tatttattgt 114960 tatttatttt atttagagat tgttattttt tgtttgggtg tgagtgtgtg tgtgtgtgta 115020 aattgtatat gtgtgtatga aatggaatta ggatttttgt atatattttg tgttttgtta 115080 tttttattta atatttttgg tattttttat ttttaaaaat gtgattttaa tgatggtgta 115140 ggtttttgat atatgggttt agaaaatttg tggaaatttg gattgttttt aggttttgtt 115200 agtttaatgt tgatgtaaat gtttttgtat gtaaattttt ttgtattttt gattattttt 115260 ttgggataaa tttttagaag tgggttaaag tatatgaatg gtttttaggt ttttggagta 115320 agttgagatt ggtggggatt ggagaaggga tttagggagg tttttgggag tttgtgagat 115380 tggagtttgg ttttagggga tttgaattta tagatgaagg agatggttgg taaaggtggg 115440 aattttttgt tttatgggtg ggggggtgat attgttttat tttttagtga tagtatgggg 115500 atttttttaa tatgatttgg ttttgtattt ttttgatatt gtgtatggtt tatagttgtg 115560 atgtttagtt gggagttttt tttgtgtttt ttagttgtat taattttttg tagatagagg 115620 aggaagttgt ttggtgtttt tttttgttgt gtgggttttt tgaatttgtt tagttgggtt 115680 tgtggatttg tgtagttatg tatggggttt taaaatttgt aaaatgataa gtttatgaat 115740 atttttgttt ttgtgggtga atgtggatat tttttggttg tgtttttttt tatagggaag 115800 atggagatgt gtaaagtgat aaggatttgt tatttttggg taggttatgt tggttttatt 115860 gtgaggatgg tggtaggggg ttttttagga ggtttgtata ttgggaagag aggggtgatt 115920 gtgtgtgatt gtaggattta gggtgtagtt ttaggatttt gatgggggag gagatgttgg 115980 ggagttttgt tttgttagtt tggtgataga tattttttaa tgttttttgg ttgggtataa 116040 tttataatgt tttttgtggg gaggtaattg tttatgaggt atttttggta gggatgattt 116100 tgttttattg ttatatattt tagtaatgaa ataagaattt agagtgatgt gatttttttg 116160 atgatttttt taattatttg gggtttttgt gtgattttaa gaagggggaa ggaggtagtt 116220 tttgtttttt tgggtttttg atgtggtagt tttggaatgg ttatgtgttt gttggtttat 116280 agtgggttat ttgttgaatg tggttgtggt gggattgggg ttgggttgga gagtgggtga 116340 ttatattagt tagttttatt ttgggttatt gtgtagttag gggttttatt tttttagggg 116400 ttttgttgtg agtgttttgg ggttgttgga ataaattatt ggaaattaag tggtttaata 116460 aagattgatt tgtttatggt tttggaggtt ataagtttga tattaaggta ttggtaggat 116520 tatatttttt ttgatagttt gaggggagga tttttttttg ttttttttag tttgtgttgg 116580 tttaggtgtt ttttggtttt ggtagtattt gtagtttttg tttttattat gtagtttttt 116640 ttattgtgtt tttttgtgtt ttaagttttt ttttgttttt tttttataag gatattgagt 116700 attggattta gagtttattt taaatttagg atagttttat tttgggattt ttaattatat 116760 ttgtaaagat ttttttttta aataaggtta tatttgtggg tttttggggt taggtattag 116820 atatgttttt ttgggggtta ttagttaatt ttttatagaa ttttagatga aagtgaattt 116880 ttataggttg aaatgggggt gaaggtttag tgtgtttttt ttttttggga gtttttttag 116940 ggtttgtgtt tattttgtga ttttgtgatt tagttttttt tttgagatga agttttgttt 117000 tgttgtttag gttggagtat tgtggtatga tttgggttta ttgtaatttt tgttttttga 117060 atttaagtga tttttttgtt ttagtttttt aagtagttgg gattataggt gtttattttt 117120 atgtttagtt aattttttgt gtttttagta gagatagggt tttattatgt tggttaggtt 117180 ggttttgaat ttttgatttt aggtgatttg tttgttttgg gtttgttttg gttttttaaa 117240 gtgttgggat tataggtatg agttattatg tttggtattt agtaggtttt ggttgttttt 117300 tttttttgag atagagtttt attttgttat ttaggttgga gtgtagtggt gtgattatgg 117360 tttattgtag ttttgatttt ttggttttaa gtgatttttt tattttagtt ttttgagtag 117420 ttgggattat aggtatatgt tattattttt ggttaatttt tgtattgttt agtggagttg 117480 gggttttgtt atgttgttta ggtttgtttt gaatttttgg gtttaagtga tttgtttatt 117540 ttggtttttt aaagtgttgg ggttataggt gtgagttatt atgtttggtt tagtaggttt 117600 tttagaagtg tttgaggttt ggtgaaggta tggtgttatg gagtagagaa tatttaattt 117660 tgtttttggg gagttggaat atattttttg tagttaattt taatagttat gatgtggtta 117720 ggatgatatg gggagggggt ggtgtggatt gtgtgggagg ttagtttttt gggaaggggg 117780 ttggagtggg tttggttttg aggaggattt ttaagaggag gaggaggtgg tggtatgttt 117840 gtttgggggg atggtgtgag ttagggtggg tattttttta tttaggtgtt atttttttga 117900 tattttagtt gggatatggt ttttttgggg aagatggata tttttagagt ggggtatttt 117960 ttggggaaga tggatatttt tggaatgggg tgttttttgt ttttattgtt tttttagtat 118020 atagttgtat ttttttgtag ttttggaggt tgtgagattt tttggttgtt atttagaata 118080 aatttgtttt tgagtagtgt tgttttgatg gtggggtggt ttttgtgggt ggaatagttt 118140 ttgttgtttt agagtttatt gagagttagt gggtatggga gtggtgttgg attgaaatat 118200 ttagagggat tatagagtta ggtagtaagt atagaggtta gttagtgggg agggagggat 118260 ttatttatga aaagatatta agtattgaaa gagaggagag gatggttggg gattggtata 118320 tatgtgtatt ttgtgtagat ggttaaggtg gtgaggtgtt agttatgtag ataattggag 118380 gaaggaggag tgttttaggg gaggggttag ttttggtttt agaatgattt gtttgtgtat 118440 gtgggtttgg ttggaataaa ttattgtatt tgtattgtag atttaattgt aagtttatat 118500 tagggtagtt tttgttttgg tgtagtgttt ttgattatga gttggttatg gtgggggtga 118560 ttttaagggg atttttaagg agggggttta ttggattttt tagggaaggt tatttgtttt 118620 tttgggttgg atttgggata aggttttttt ttgtttagtt tttgtttttt aatttgattg 118680 tatggaagga tgttgaggat atttggaagt tggtttttgt tttatagtat ttataggata 118740 gaggtatatt atgtggggat agtttggata gtgtttagga ggtagggagt agattagagg 118800 attgtgggag gttttgggaa ttgtatgagg atttaggtat tgagttttgt attttttggt 118860 attagtttga tgtatagttt ggttttgtgt ttattttgta ttttattttt tttatttgta 118920 tgggggtggt aataatattt tttatagttt aggtttaagt gggtgtagat gtgatgagtt 118980 tggtaagttt attttattat atttagtttt gggtattgaa ttttggattt tttggttggt 119040 agaagtggat atttaatttt tttttggggt tttggggttt ttgtagaatt agaatatagt 119100 tagtagtttg tatgtagggt gtagagggat agagggatat tatgttggga gtttatattt 119160 ggtatatttt tgattttggg gtttagtgtt ttgttgtttt gtggttatgt gattagttag 119220 aggttatggt tggatttata ggtgaatata gtttgtggat ttgattttgt ttggttttgt 119280 ggtgttttat tttattttta gttttagttt gtggagatag agttttgttt tgttagttag 119340 gttgagtgta gtgatatgat tttagttttg taatttttgt tttttgggtt taagtgattt 119400 ttttgtttta gttttttgag tagttgggat tataggtgag tgttattatg tttagttaat 119460 tttttatttt tagtaaagat ggggttttat tatattagtt aggttgttta gtgttttaaa 119520 aagggtttgt tttgttttgt gttagtattt aaagattagg agatattata taaagattta 119580 gatttttatt tttttgagaa gtgaatagtt ttggttatgt tgggtttata ttttttaggg 119640 tagtgatgga gttgagatag ggtttgtgat aattgagagt tttttggagt ttatatggtt 119700 ttttgtttag tttttggtgg aggttgagtt tagtgattta ggattttgtt tgtgtttatt 119760 aagaaggaga ggtgtttgtg gtttagagag ggtgtttata ggagtgtttt gtttaggaag 119820 ttggtagttg aggtggttag ggttaggggg ttgggttttt tttttttttt tttagtgttt 119880 gagtgtattt ggaggaagag agatgggtga ggggaaggta ttgaaattgg ttttggagtg 119940 ttattattgg gggttgggga ttagttgtta tttttttttt tgtgggtagg ggaggtagtg 120000 gtgggatttt atgagatttg gattttgtgg tttggtgagg tagggagtgg ttggggagat 120060 attgtgggtt tttatagggg tgtgttgtgg gtttggtttg gggaaggagt tggtgaatgt 120120 gtttgttatg tgggtttttt tttgttttgg ttttgataat taggagtggt tggtttttat 120180 ttggagtgtg gttgtgggga ttgtggaggt ggtagttttt taggtattat ttttattgtt 120240 tttgagggag tagattttgg tggagaggta ggatggttgt agggtgggag ttggtggttg 120300 gtattattgt atgggtttgt agtagtggat gggaagatgt aggagaggtt gatgattgag 120360 aaagttggtt tttgtggatt aagttggggg agttggataa ttaagtggtt agaattttgg 120420 gttttggtat tagtttgatg tatagtttgg ttttgtgttt attttgtgtt ttattttttt 120480 tatttgtatt gggggtattg gtatttttta tattttaggg ttaagtggtt gtagatgtga 120540 tgagtttggt aggtttggtg ttttgttggt attgaaagtt ttagtgtttg tttttagtgt 120600 tattgatggg gttttgtttt tgttgtggtt ttgattggtt atagttgtgg ttatttatta 120660 ttggaggtat gttttttgtt gtggttgatg gtagaggtgt gtttgttggt ggtgttttag 120720 tgtgtgtttt ggttggaggt gaggagggat aaaaatagtt gtgataagaa ggaaattaag 120780 gttgggtatg gtggtgtatg tttgtaattt tagtattttg ggaggttgag gtgggtggat 120840 tgtttgaggt taggagtttg agattagatt gattaatatg gtgaaatttt atttttatta 120900 aaaatataaa aattagttag gtatggtggt ttgtgtttat aattttagtt attggggagg 120960 ttgaggtagg agaattgttt gaatttggga ggtgttgttg tattttagtt agggtaatag 121020 agtaagattt tattttaaaa aaaaaaagaa ggaaataaaa gttttttttg gaattagaat 121080 gtttttatgt agatgtagtt ggagggggag gttgtgtggt ttgtgttgtg gttatggtaa 121140 gatatgatgg gtagtatttt tttattttag tttgtatttt tgttttagaa tttatgatgg 121200 tttttttagg atggggttgt tttttttgtt tgttgagata tgaaggatgg gaagagattt 121260 ttggttttta ttgttgtatt gtttgttttt ttttgttgtt ttttagtagg aaatatgttg 121320 gagtgttttt tagttattta tttattaatt gtattttttt tttttatttt ttagttttga 121380 aaagattttt tgaggttgag gaggttgaga tatttaattt tattttattt tggagggttt 121440 agattttttt attttgagtt attgtggtta gttttattta gaaattttag gatttgggtg 121500 tgaagaattt agaatttttg gtttgttatg tggatttttt aagttaatgt ttttttaagg 121560 tgtttttgtg gagggtggag tttttgggtt ttaaggtggt tgagttggtg ttttggtgta 121620 ttgagttgtt tattgatatt ttgtttaagt aggtggagaa tgttggggtt attggtttgt 121680 tttggtttgg gtttaagagg gttgaggtgt tgggttataa gatgttagaa ttggtttttt 121740 ggaggatgga gattattatt gttaaatttt aggagttagt ttattggagg atggagtttt 121800 ttgtttttaa ggtttttgag gtgtttattg tttttgttat tgatgtagtt tttaagaggg 121860 tggagattta gatgtttaag tttgttgagg tgtttattgt ttttagttta gtttagattt 121920 tggagaattt agagtttgtt tttgtgtttt agttgtagag taggttggag tttaagtttt 121980 agttttttgt ggttgaggtt atattttgga gttaggaggg tgagttgtag agtgttaggt 122040 tttggatgtt gtggtaatgg ggggtttggt tgttggtttt gttatagaat tttggaggaa 122100 gaagttggat atggggtgga gggtgttatt ttggagattt agaaagattg gaatgtatgg 122160 gggtgggggt ttgtaagttt aggagaggtg gttttttttg tttgatggga atatgttaag 122220 atgttttaag tgggatttga atgagagttt ggaaagattt tttgggtttt aaggagtttt 122280 ttttatgggt tattgtgggt tttgttggga tttttgtttg ttgtgtgttt ttggagggtt 122340 tgggaggttt agagaatgag gagttatgta ggaattaggg taggtttatg taggggtgta 122400 ggatagggtg gagttgagat ttttagaagg gttgttatat tttggtggtt tttgtttgag 122460 gaattgtagg ttgtttggat atgtttagta gaggttgagg gtttggggaa gggaggaggg 122520 atgtatgttt tttgaggttt gtattggagt ttatggtttg gttttttttt tttaggaggg 122580 atggttgtgg tagagggagg ggaatatgag gagtatttta gtttgtagga taaaattttt 122640 agggtattgg gaaggggtgt ttggattagg gggttgtgtg atagttgtat atggttttat 122700 ttgggggtgt ttttttggtg agaggagaga ggttatgggg ttttagtagt gttttgggag 122760 ggtttaagtt tatagttgtg ttgatatgga gtttataggt aggggattgg tgttagtttt 122820 gtgggatata gggtttgttt ggaaatgtta ggttgtggga tatggttggg ttttttttta 122880 gaagtgtgtt ttttggtttt agtagggatt gtggttttat ggggttatag taaggtgtta 122940 gttgggttag aagtttttta agagttaggt ttgattttgg gtataggatt agaatttagt 123000 aatgtttagt aagttttttt taggttggat aaatagtata gtttgggttt ttgatttagt 123060 tgttgttttt tatttttaat tgtggtgaaa tatataatat ataatgtgta attttagtta 123120 ttttgtagtg tatgttttag tggtatttag tatatttatg gtgttgtgta gttgttattg 123180 ttgtttattt ttggtatttt ttttattttt ttaaattgag ttttgttttt gttagattaa 123240 gttttttatg tttttttttt agttgttggt agttattatt ttattttttg tttttattat 123300 gaatttattt gattatttta ggaattttgt gtgtgtggaa aaatataata attgtttatt 123360 ttgtgtttgg tttattttat ttagtatgat gttttaaagg tttatttgtt gtgttgtagt 123420 atggggtaga attttttttt ttttagaggt tgaataatat tttgttgtgt gatgtatttg 123480 tgttgtgtag ttgttttttt attggtggat ttttgggttg tttttatatt tttttaagtt 123540 ttttttttta ttttttttga tttttttttg atttttttga gatagggttt tgttttgttt 123600 tttaggttgg tgtgtagtgg tgtgattatt gtttattgta atttttgttt tttgggttta 123660 agtgattttt tagttttagt tttttaagta tttaggatta taggttgtgt gttattatgt 123720 ttggttaatt tttaaatttt ttttgtagag ataggttttt attaggttgt ttaggttggt 123780 tttaaatttt tgggtttaaa tgagtttttt gttttggttt tttaaagtgt tgggattata 123840 ggtatgagtt atttaatttt tttttggttt ttttttttga atgagagttt tttagtggtt 123900 agtgggtttg ggggttggga ggatgtgggg tttggagagg gtgtgggttt ggggggagat 123960 tagtgttttt tatgttttta tgggtatgtg gagtgtatat ttgttttggt gggtttgggg 124020 tttgggattt tgtatttttt atagaggggg tattggaata tattgagtag ttagaggtta 124080 gtgggttttg gaaggttttt tttggttttt agtgtgtgag ttttgtgttt ttttttttat 124140 ttttttaagt ttgattttga agagttattt tgttttagtt atttagattt agtgatagtg 124200 gttgttggtg gtatggtgtt aggttaaagg tatgggtagt ttgtagagtg gtaggaggtt 124260 gttttttttt ttgttttttg ttggtgtagg atttttgttt gatgtgttgg atatattttt 124320 attttgggtt gatgtgttta tatttagttg agttaaatag gatgtggttg gggaggtggt 124380 tgttattgag ttatttaaat tttggtgatg gttggtgttg gatgtatagg gatgtggttt 124440 tggttttggg ggataggtag ggggatgttt atggggatgt ataagaatat ttttttttag 124500 gggtagatat agtttagttt ttaaattgtg ttagagattg tgttgggagt taggtttagg 124560 gatataattt gtgggttttg ttttttggag tttattgagt tgtgagtagg atggttggga 124620 tataaggagt gtttagggag tttttttagt agtggaagta taattttatt aggttaggaa 124680 ggggagagaa aggtaggtta tgtggaggta gtagtgttta gagttgttag gaatttggtg 124740 ttttgggggg atggtggttt tttttatgga ataggatgta tatgttggag ttggggtatg 124800 ggagaaaatt attagtattt tagatttggt tatttatgga tagggatttg tgtaggtggg 124860 agtttagttt atgtggagag gtttgtgggt tgggttgata gttttgaggg tttaagtaag 124920 tttaggtgga ggaaatgtag ggatagatga gggtagggtt tttttaatgg aggagtgttt 124980 ttgaaatttg atgggagtgg ttttttgggg ggtttaggtt tgagttttat tagttttttt 125040 tttgaggtat tatttgtttg tttttttgtt tttttttttt gtgttatgat tgttttggat 125100 atggatttag ttttttttaa tttagttttt tgtttatttt ttttttaggt ttattttttt 125160 ttgttttttt atgtggggtt gggttgggag ttttttgagt tttgatatgt atagttttga 125220 ttaatttttg tggttttttt gttttttgag tattagggat ttagttggta ttatggggaa 125280 aggaattatg gagggagttt tgtgtttttt gagtagatgt ttagtttttt ggtttttgtt 125340 tgtgggaggg tatttgtgtt gtggtttgtt tttattttag agttgtgggt gtagggtagg 125400 gttttttggg gttttagttg aattgttttt agattgattt ttttaaagta tagtattgtt 125460 gagatttttt tttgtgttga gttttttttg tttatttatt ataggttttt ttatggttga 125520 tttatttttt tgtttagttt atattttttt tttttttagt tttttttgtt ttggtttttt 125580 tttggttttt tatatttttt tttataattt ttttgttttg attttttgaa ttttgatttt 125640 tgtttttttt tatattattg ttttggtgaa tttttatgta ttttttaaaa tttggtttaa 125700 atattttgtg tttggtttgg gatataaatg atttgtgtat aaattttttt ttttttgtta 125760 gatttttttt tttaaatgtg aaagtagttt tttagattat aaaaagtaat tgagtatttt 125820 ttttttaaaa tgtaggaagt atagaaatga gaaagaattt aaaatttatt tgtaagttag 125880 tgatatttat gtttgaggtt ttgttgtata gtttttaaaa ttttttttat gtttttatta 125940 gattttgagg gtagggttgt tgtttttgtt tttttttgtg tttttttttt gttttttgtt 126000 ttttgagatg gagttttttt ttattattta ggttggagtg tagtggtatg attttagttt 126060 attgtaattt ttgtttttta ggtttaagtg atttttttgt tttagttttt tgagtagttg 126120 ggattatagg tgtgggttat tatgtttggt taatttttgt atttttagta gagatggggt 126180 tttattatat aggttaggtt ggttttgaat ttttgatttt gtgatttatt tattttagtt 126240 tttttgattt tttaaagtgt tgggattatg ttattgtgtt tagtttgttt tggtttttat 126300 aaagaatttt ataaggggtt aggtgtagtg gtttatgttt gtaaatttag tattttggag 126360 gttgaagtag gtagattgtt tgagtttagg agtttgggat tagtttgggt aatatagaga 126420 aattttattt ttataaaaaa tataaaaaat tagttaggta tgatagtatg tgtttgtagt 126480 tttagttatt ggggaggttg aggtgggagg attatttaag tatgggaggt tgaggttgtg 126540 gtgagttgag attgtgttat tgtattttag tttaggagat agagtgagat tttgttttaa 126600 aaaaaaaaaa aaaaaaaaaa aaaattttat aagatattaa gtaagtgatt tggatataat 126660 aggtgtgtta tgaaattatg ttgaaggagt gagttattgg tggtgagttg ggatggtttt 126720 tttgtggttt ttgtaggtag atgtagtgat ttttatgggt tgtttttaga gattaagtag 126780 aaattttttt ggttaatttt atttttagga tatttggttt tttttttgga ggttgtgttg 126840 gagggtttag tgggtgggtg ttggttttag tgtgggggtt ttggaaggag ttagtatttt 126900 aggagggagt gtgggtattt agatggttga aggggaggga gaggaagaga ggtgttgtag 126960 agggtagagg tatttttgtt tgtttttttg ttttagggtt tggtgaggtt tgagttttat 127020 gttggtgggg tggatttttg gtttttgagg ttttggtttt gtttttggat ttggtatttt 127080 ttttgttgtt tttttataga agggtgttta ttttttgggg ttatttttgg tttttttagg 127140 ttttgggtgg ggatggtttt gttttttttt ttggattttt gttttttttt tgttttttaa 127200 tatgggtgtt tttgggtgga gtggggtggg gttgggttgt agtatttagt attgagtttg 127260 taagggttgg ttgttggttt agagtttttt ttattagagt tatttttttt tggtttttta 127320 gttatattag ttaagttttt ttagagttgt tttataaggt gggtgtttag tgtttgttta 127380 tgggtttggt tttttgtttt tttgggatgt ttattggggg taagagggag gttaggttta 127440 gtgtttagtt tagttttggg tatgttttag ttttgtttta tgagttaatt ggttttgaat 127500 tattatttta ttttttttag ttttaatttt ttgatttgtt aaagaggtat ttgtagaggt 127560 ggttgggggt tgagttttta tgtatttatt tattttaaga attaagaagg gagtttatag 127620 tggttttggg gttatttgtg aatatggatg tgaaattggg gtggggtaga tatggtagta 127680 tgttttagta gtttttttgt gatttagagg gtttggaaat ttttgttatg tgggtggagt 127740 gttgagggag tagggggtta ggtttttttg agttgatgat ggtgggtgtg gttttttgta 127800 tatttggttt gtattgggtt gtgtgtttta ggggtagaat agggaggaat tttagtatag 127860 atagtagggt tgttagtata gtgttgagta tagggttaat taaagtatag ggttttttgg 127920 aattatttaa tatagagtag tgaagaggtg gttttgggga aagtggggtt agagttgagt 127980 ttgagtgggg ggtggggagg gtgggtatta gtttgtaagg gagggatatt tattgggttt 128040 tagaagtttt tggtggggat tagggattgt gaagttgggg agagggtgat tattgtgatt 128100 tagggaggaa gggttttata gatagtttag tttttggttt tgtgtttata ggatatttta 128160 tataggtttt gagtttattt ttggattgtg gattttttga ggtagggtgt gtaggtttgt 128220 ttagtattag gtgtaaggta gggggttttg gtaagtgttg agggatttat tggtgtttga 128280 tgaagtagtg agtttggatt gtgttatgtt ttgggttttg agtttgtagg atttttttgt 128340 ggggttgtgt gtttttgttt ttggaggtgt ttagaaggta ttgatgtttt tgttgggatg 128400 ttttatttgg aaggttttgt tgtttttatt tttttttatt tttttgagtt gtttgtagag 128460 ggtatttagg ttttttttta ttttgggatt gggttttttt tttttttttt ttttaagaat 128520 aagtattttt tttttttgaa ttgtttttgg agttttttag atttaggttt agagtgggaa 128580 gttttgtatg tgttggggga ataggaatta atgtgggagg attggttagg tttggtgtgt 128640 tttttttgtg gtgggatggg gtggggttag agaatagagt ttggttttag agtttaggaa 128700 gagaattttt ttttttgttg gtttgttaag tattgtgtag tggtgagagg aaaggagggt 128760 tggtttggga atgtagtggg tgttgagtag ttgtggaata ttttaaatag agtgtagttg 128820 tggggaaggg tggggttagg aggtaggtgt tgggggtggt ttttttgttt tgttttttgt 128880 agttttgtgg ttttgattat ttagtttggt tttaggatgg agttttggtt tttagatata 128940 tggtattggg tgaggttgtt ttttagtatt tgttttagga agttagagta gttgttagaa 129000 gagagaggag ttgtgtttgt atttgttgtt ttttaggttt gggatagttg ttgggattga 129060 gggtttgtat aatggtgagt ttgtttggag gggtgtgttg tggttagata gttatgtttt 129120 gtgtggtgtg gatagagggt atatttagtt ttggaggagt gtatttagat tttttgtttt 129180 ggggtttaaa gtgtgggtag tttttaatta gattttggat tttagtagat agtttgggag 129240 gatgttatgt ggtttatttt gatatattgt tttatttgtg attttatttt tgagagttgt 129300 agggaggtgt ttttttagtt ggattttatt ttttttttgg ggttttttgt gggtgttata 129360 agtgattttg ttttttttag tttaaggggg gtttttgggg tatgggttgt aattgatagg 129420 ttagagtagt ttatggttag ggttgagttt tttttttgtt ttttttgaat attgggttta 129480 ggaaggggtt aaagtggaga tgttttgatt aaagttgagg gaggtatgga gtttttttga 129540 ttttgttttt ttattttatt gttgttattg ggtgtatttt gtggagtttt aggattttta 129600 aagaatttag agtggagatt tttggtttta tttagtgtag gtgaggggga aagtgatttg 129660 tttatagtta tatggttatt attagtatat ttgggttaag tttgatttta ttttatggtt 129720 tttgtttgaa atttggaatt ggaaatggtt ttggaaatta ttgattttat ttgttgtttt 129780 ttaaaatggt ttgtagaggt taagatatag atttttgtaa tgttttgttt atttgtgtgt 129840 ggggaaatgg tagaggagta ttggttttgt ttttatattg tttgggttgt tgtttttgtt 129900 ttgtttagtg gttttttttt ttggtttgtt tttttattgt ggaagtgggt ataatttttt 129960 ttgtgtagtg tggttagagt ggatagtgat gatttgtgaa gtagggtgga gtgtttgggg 130020 gatttgtgtt aaataagtat ataaataaaa gttaatataa tttttattta attagtaagt 130080 aggttttgtt tgaagttttt gggtagtatt ttatgttatt tttaggtttt aggttggtgg 130140 tgttgttttg tgtttttttt atttgtaagt tggtgtttag aagttttgtt ttgtgttttg 130200 gtttttattt tttttgtgat tttttttttt ttttatttta aaaagtaatg tatgatgggg 130260 tgtggtggtg ggtatttgta gttttagttg tttgggaggt tgaggtagga gaattatttg 130320 aatttaggag gtggaggttg tagtgagttg agattgtgtt agtgtagttt agtttgggta 130380 atagaataag atttttattt gggaaaaaaa aaaaaaagtg atgtttagtt atttttagat 130440 agaaaatgaa gattatatga aatttggaaa gaagtttttt ttttttattt tttaattttt 130500 ttttaagggg tggttatgtt gatagttggg tgtggtattt ttttgaattt tatttttgta 130560 gagttattta gggtttgtgt aaaaaaagtt aatgtgtaaa tatagatttt ttaagaatat 130620 aaaggaaatt agatttttgt tattagtttt tatttttttt atttaataat attgttgtta 130680 tttgtagatg tagtatgttt tttttttttt tttttttttt ttttttttga tagagtgtgg 130740 tttaggttgg agtgtagtgg tgtgatttta gtttattgtg gtttattgta atttttattt 130800 tttgtttttt gtttttaagt gatttttttg ttttagtttt ttaagtagtt gaaattatag 130860 gtgtttgtta ttatatttgg ttaatttttg tatttttagt agagatgggg ttttattatg 130920 ttggttaggt tgtttttgaa tttttgattt tgagatttgt ttattttggt tttttaaagt 130980 agtatgtttt ttttaatggt tgtgttatta gttgttttat ggttttgtta ggtttgttta 131040 gttttttatt gtgattgaga ggttgtaata gatgtttttg tatttgtata tgtgtatata 131100 tgattgaagg atgagttttt agtgaatttt tgtgttaagg atgtgtgtat ttaagttttg 131160 atttgttggg tatagtggtt tatatttgta attttagtat tttgggaggt taaggtgggt 131220 tgattatttg aggttaggag tttaagatta gtttggttaa tatggtgaaa ttttattttt 131280 attaaaaata taaaaattag ttgggtatgg tggtttgtgt ttgtagtttt agttatttag 131340 gaggttaagg taggagattt gtttgaattt agtaggtaga ggttgtagtg agttaagatt 131400 gtgttattgt attttagttt gggtgataga gtgagatttt ttattaaaaa aaaaaaaaaa 131460 aaaaaaaaat tgatttttgt ttttgaattg gtttttaaag tggttattag aattttttag 131520 gatttttttt tttgttgatt tgtttagttg tttgttgggt tttgtgtagt gatggtttag 131580 tagggaggtt ttatgttttt tatttttggt tgagggttaa atgtttttta attggtgttt 131640 tattttgtgt attttggtta agtgagaggg attatttttt tgtatgttat aggttagggt 131700 tttgtgtttt ttttttattt ggaaggtgta tttttttttt gttgaaattt tttaaaaaga 131760 gttttttgta agttaggtgt gatggttaat atttataatt ttagtatttt gggaggttga 131820 agtgggtgga ttgtttgagt ttaggagttt gagattagtt taggtaatat ggtaaaattg 131880 tatttttgta aaaattagtt gggtgaggtg gtgtgtttgt agttttggtt atttgggagg 131940 ttgatgtggg aggattattt gagtttggga gtttgaggtt gttgtgagtt gtggttatat 132000 tattgtattt tagtttgggt gatagagtga gattttgttt aaaaaaaaaa aagagttatt 132060 tgtatatttt tattatagta ggtatgagta ttttgttttt agttgtttat ttttgatttt 132120 gtttttggga tgttttttta tatagaatat tttaattttg atattgttaa gtttttgttt 132180 ttttttttag tttttggaat ttatattttg tttagaggtt ttttgtgttt tgaaattata 132240 ggaaagaatt ttatttatgt ttttttttag tatttttgtg gttttatttt tatatgttga 132300 aattatgaat ttattggaat gtattttggt tttagtagtg aggtaggggt agatggtatt 132360 gtttggatat atagtagtga gtttggtttg gagtgggtgg ggtgtgtgtg tgtgtgtgtg 132420 tgtgtgtgtg tgtgtgtgtt atttttatta gttttggtgt ttgtattgtg ttggtttagt 132480 aaaaataatt tggatgtatt ttttttattt tttgtttttt ggaatatttt aagtagtaat 132540 ataataattt ttttgttaaa attttttaag aatttatttg tgaaattatt tgagtttgat 132600 atttttgggg gagtttagta ttttaaaaat ttaaattttt tttatgggtt tgtgagtttg 132660 ggagtttttt ttttttttta aaatttatta ttattttttt tttagaaaag tgttttttag 132720 tttatttaaa atttgttagt ttattttgag ggggttgttt tagtttgttt agtgaggata 132780 gtgtgtagtg tggtgattga tatgattgat tagtagagta tgattgatta gttggtgtgt 132840 aaatatgatt gattgtggtt agtgttttgg gatgttttat gttgaggtat atgtgtgtag 132900 tgtagggtga tgtgtatttt gagaggggat gaagttatag gatttttgta tttttaggag 132960 agagtttttt tttttaaggt tgtagttttg agtaggtagt gatgggattg ggtttagggg 133020 gttgagtggt tttagtaggt taagggtttt aggaattatg agaagtttgg agttgtttag 133080 agagtagttt ttaaaattag tttggattgt agtttttaga aagatatgtg attgatatta 133140 tgaattagga tatatttata tatggggtgg gggtggggat gggatgtatt aatgaaatta 133200 aatttttgtg atggaatttt tatttttatt atgtgtgtgt tatatttagt attttttttt 133260 tttttttttt tttttttttt tttttttttt ttttttgttt gtttgttttg gagagaggga 133320 aggttttttt ttattttttt ttaaatagtt ttattgagat ttaagtaagt tattatataa 133380 tttattaatt tatttattta tttatttttt tgagatggag ttttattttt gttgtttagg 133440 ttggagtgta gtggtgttat tttggttgat tgtaattttt gttttttggg tttaattaat 133500 ttttttgttt tagttttttg agtagttgag attatagata tgtattatta tgtttggtta 133560 attttgtatt tttagtagag atggggtttt tttatgttga ggttggtttt gaatttttga 133620 ttttaggtga tttatttgtt ttagtttttt aaagtgttgg gattataggt atgagttatt 133680 gtgtggttta atttatttat ttaaagtgta taattttatg gtttttagtt tatttagaga 133740 gtagtgtaat tattgttatt ataattaatt ttagaaaatt gaaaatttga gaaatttaga 133800 aaattttttt tttaagaaga aattttgtag tttttagtta ttaattttgt tttttttttt 133860 tatatttttt ttttatttgt gtggattttt tttttttttt tttttttttt tgagataggg 133920 ttttattttg ttatttaggt tggggtgtaa tggtttaatt tttgtttatt gtaattttta 133980 ttttttaggt ttaagttatt tttttattat ggttttttga gtagttgaga ttataggttt 134040 gtgttattat gtttggttaa tttttgtatt ttttgtagag atggggtttt attatgttgt 134100 ttaggttggt tttgaatttt tgggtttaaa tgattttttt gttttggttt tttaaagttt 134160 tggaattata ggtgtgagtt attgtgtttg gttgatttta gatatttttt gtatagagaa 134220 ttgtatgttt ggtttttgtg tttggttttt ttatttggtg ttatgttttt aaggtttatt 134280 tatattgtgg taggtgttag tgtgtttttg agtaatattt tattatggta tggattattt 134340 tattgtggat agatatgttg tttttattag ttgagggata ttgggttgtt gttattgttg 134400 gtgagtgtat tttttttaaa ttaaaaaaaa aatgttggtt attatttatt agattgtttt 134460 tttggtttat agggtgggat aagttggttt gggtgagggt taggaggtgg ttaggtggag 134520 gtggttggag tggttttggg ttgtttttgg gtgtagtagg tagaggtgta atggtagagt 134580 ttgagtaggt tttttgggtg gatttttatg ttggtaatgt ttgtttattt aagaagtttt 134640 ggttaggtgt ggtgttttat atttgtaatt ttagtatttt gggaagttga ggtaggtaga 134700 ttatttgagg ttaggagttt gagattagtt tggttaatat ggtaaaattt tgtttttatt 134760 aaaaatataa aaattagttg ggtgtggtgg tgtgtatttg tagttttagt tatttggtag 134820 gttgaggtag gagaatttgt ttgattttag gaggtagagt ttgaatttag gaggtggagg 134880 ttgtagtgag ttaaaattgt gttattgtat tttagtttgg gtgatagagt gagattatgt 134940 tttaaaaaaa aaaaaaaaaa gaaaaaaaaa gaaattttta gtgttgtttt gtgtttggta 135000 ttgaagttga gggaaggtag tattagtatg agtttttagt ttattgggtt tttgtttgga 135060 gttgatgtgt gattaaggta tatgagggaa gtatggtgag gtggatggtg tggaggtata 135120 aggagtaaaa taaggtagat gtagtggttt agtggttttt ggtggttgtg aggagtgtgg 135180 gtaggatagt tttaggaggg tatttggaga gtagggttgg ttggggtaag gtgtgttagg 135240 tatttgttag gagtaaaatg taaggggata ttaaagagtt taggaattaa tatagatagt 135300 atttaatgta gtatttttta atattgaaat gatgtatagt aatttttatg atgaataaat 135360 gttggaattt taaattaaga taggtttagt tttgtatgtg tatagttttg ttagagtttg 135420 tttagtgtgg aatttgattt gtttaaaatg ttgttttaaa atattgtttg atttttggat 135480 tttttggtat tgttttaatt tttgtatttg gatgaaggtt ttattttaat tttagttgga 135540 gagggttaag ggttggtgaa tttggttttg gatttgtaga gtttgtggta tttgagaggt 135600 ggggttagga ataggaagga gttggtgaga atggtatttg gtatgggatg gggttagatt 135660 agagtagtat tgtggttttt tttaatttgt ggttttgttg ttggatgttt ggtgttggtg 135720 ttgagttttt ggttttttga atggagtgtg atgaataatg gggttgggga gtttttgggt 135780 ttttttttga agtagtagtg aagttaggga tatgttggta gtaggtaggg agagggatgt 135840 ttggtttgtg tttggagtta gttgttttat ggaggagttg ggtgaggatg tggtgggagg 135900 aagatttttt tagttttgta ttttttgaag tataattgag tgtttgtgtg gtttgggggt 135960 tattttggtt tgaggatagt tttgttttgt ttagttaggt tttgaagagt tattgggata 136020 tggatagtag ttttgttggg tggtaggttg tttatttttg tttatttaat gttggaattg 136080 gatgtagagt atttggatgg ttagttttag agtgtttttg atatttttag ttattttatt 136140 ttttagatta ggataagatg tgggatttta attttgagtt ttttatgggt tttattttat 136200 gtgtttttat aagttattgg gtttattttt tggttttagg gttgtttggt tatttggtat 136260 tttggttttt ttatttgtat aatgaaaata atagttttag tttttttgag gagttataag 136320 atgttttttg tgtgaaaaat tgggatttgg tattagatta tttggatttg aattttggtt 136380 ttattttttt taatttgtgg ttttgggtta atttggtttt tttgttttta gtttttttat 136440 ttatagagtt attttattga gttgttggga ggatgaatat aaggaagtgt atttatgtgt 136500 ttagagtatt gtgattttat ttattattat taaatgaggt atataataag tgtttaatag 136560 atgtttagtg ttattttatg gattttgtgt gttttgtgtg tttttagtag ttaagttttg 136620 gaggtgggga agttgttgat gagttgtatg aggtaattag aaagaggagg ttataggtgt 136680 aagggtttgg gtgatatttg tggatagaga gaggttgatg gattttggta gaggggaagg 136740 gggtttttgt atatagaaaa tgttttttgt atttaagatt tttgtgattt tggaatagag 136800 gtagtagagg tttgtaaatt ttaaattata aatttagaaa gtatagaata tttgtagaga 136860 ggattagaaa tattatatat tttagtgtgt atagaatttt ttatatagtt aaataaaagt 136920 atgtttttaa ttgaagttgt tggagagttt ttgaggattt tatattagat aagggttggt 136980 aagtggaagt ttaatatgta ggagttattt tttttgttta taaatgtttg ttgttttttt 137040 tgtttatatt tgtatttatg tgagggtatt tataggttta ttgtttagtt ttatgttttg 137100 tttgttatta aaaaattttt taagaatttt ttagttgtaa atttttttat tggagggggg 137160 gttttaggaa tttagttttg tttggggttg gggtatttta gtatttgttg tataggtgtt 137220 ggttattaaa ggttatgtgt tgtatttgtg ggtttttggg gtttggtggt atttgggtat 137280 atagtttagt ggtggttttt tatttgttag atattgggag tggggggttt tttatttttg 137340 ttttttggtg gtggggggag tgttttgagt tgttatatat tagaatttat tgatttatat 137400 gttgtggtat tttatagttt tttgatagtt ttttagtttg agagattatt aaattgagtt 137460 tttggagagg gtggttgttg aggtttggat ataggtgtgg ataggatagt tttgttttat 137520 tttggagttt tgttttggtt tagttttttg tgggtttgaa gtttaggttg ggttagtttt 137580 tgttttttag atggttggaa aggtagttta gttttatggt ttttttgtta ggttttgaga 137640 gttgtttggt ttttagtttt gttttttttt ttttttaaga tggagtttta ttttgttgtt 137700 taggttggag tgtagtggtg ttattttggt ttattgtaat ttttattttt tgggtttaag 137760 taattttttt gttttagttt tttgagtagt tgggattata ggtgtgtgtt attatggtag 137820 gttagttttt gtatttttag tagggattgg tttttattat gttggttagg ttggttttga 137880 atttttgatt ttaagtgatt tgtttatttt ggttttttaa agtgttggga ttataggtgt 137940 gagttgttat gtttagtttt tagttttgtt ttgatttttt tttaaggttg tgaggatgtt 138000 tatgtttttt ttttttttta tggtttattg atgtttttag atgttttgta aagttatttt 138060 ttttttggga gttttttagt tggtgatggg ggattttttg gggattattg tttaggtagt 138120 tatgtaggtt tgtgggttgt gtttttaggt tggattgaga tttggtgtat ggggtgtttt 138180 tggtttgagt tgaggttttt ggaagttata gttaggaggt agtaagggat ggttgttatg 138240 tttttttttt tttgtttttt agggtttttg tgggatagat ttttttgttt gagttttttg 138300 gttgtttata ttttggtttt ttaaagttta gtttgaagtt ttaggtattt tataatttgt 138360 tttttttagt agtttgtttt gttttttttt tgttgatgtt tttgaaattt ttttgttttt 138420 ttttattttt tggttagaga gagattggag attttgtggg aatttttgag gggagggaga 138480 aggttgttgt ttgaatggag gtggtttttt tttttgtttt tttttaggtg ggttatattt 138540 gtaggtttag ttttttgttg tggtagtgtt tggggtgttg gttgtttttt gggtatgagt 138600 tgggagttga gggaggtgtt tttaggattg gagtggtaat ttagttggag gaggagtaat 138660 aggtttgtgg ttagtagtag ttgttgtagg gattttggtg ttgtatttgt gttttagttg 138720 attttttttg tttttttagg gtgggttggg gatggtggtt tgttgtttag tttaggaaga 138780 agaggggttg taattagtag tagttatttt aggggatttt agtgttgtat ttgtgattta 138840 gttgattttt tttttttttt tagggttggt tgggaatggt ggtttgttgt ttagtttagg 138900 aggaagaggg gttgtggttt ttattttaga ggtttttttt ttggtttttt ttttggtgtt 138960 ggtttaattg taggtttgtt ttaggttgtg ttggtatttg ttgattgatg tttagtggat 139020 gttgatagga gagggttggg atggggaagt agtaagtttt ggttattgtg ggtttgggtt 139080 atagatggtt gaggtatttt ttggttattt ttaggaagta aggttttatg tagtttttga 139140 tttatttatt gtttgtgtgt attttaggag gttgtatttt ttaaggtttt tattaggtaa 139200 ttttattggg ttgggtgttg ttgtaaaatt atttattggg tgtggtggtt ttttggtggg 139260 gggtatggtt ggggaggatg tggtggagga gaagttagtt ttgtggttgg ggggagggtg 139320 gattatttgt tttttgtttg ttttttgaat tggagtttat ggtttttttt ttaggtgttt 139380 gggttatgga agaggttata gttttgtttt atttttgtgg tagtttaggg gagttttggt 139440 tagttttgtg ttttttggga gggtgatagt ttggttaggt tgtagggtag gattggaatg 139500 tagatttttg tttggttatg ttgttgtttg gttgttttgt ttggggattt tttgtttagg 139560 aagagagaag tgggttggat agtttggttt agtgattgga agtttagttt tttatgttta 139620 gtttagtagg aagtttgttt ttttggaata tttgtgtgtt tttgtatgtg tttttttggt 139680 tggtggtttt gtgaggtttt tattgggttg tgttatgttt tttggttatt ttggttttgg 139740 tgtttggttt ttgtgaaata gagatatttg ggtagttttt tatttgtgtt tgtaagtttg 139800 tgtggtttta gtgatggttg attttgtttt atttagagga tttgggaatt tttagtttaa 139860 ttgtttagag gagttttttt tagtggggag agtttgagtt gtttttttgg tggatagttt 139920 tttagatttt aggtggattt ttttgttggt tgtttttttt gttgtttttg tttttttgtt 139980 ttttatttgt tttttatttt tttttttgta gtagttagtt ggtatgggga tttttttttt 140040 tttttgggat tgtgaatgag atgatttttt tggttttttt gggtttagat ttttttggta 140100 atagttagtg aaatttttgt tttaggtggg aggagaaggt ttagtatgtg gttataataa 140160 tggttttaat tatattattt ttaaatgttg gtttttattt attttttgtt ttgtttaata 140220 gttattttta ttattttatt ttttagatta ggaaattaag gtgtagagag ttttagttat 140280 ttgtttgagg tttttatagt taagtgtttg gatttgaatt ttggagtagt ttggttgttg 140340 agttgttttg gagatggggt attgtgtagt ggttggggta ggggtggagt tttgttgttg 140400 ttgatttttg ggttatttgg agtgataata tagtttagtg tttgggtttt tgtttgagat 140460 tttggttgga tgttaggagt ttgagatttt ttagtttttt tttgtgtaag gtgttatggg 140520 gtgaaatgaa agaaaatttt agttagaagg tgtttttttt tttttttagt tttttagttg 140580 ttttggattt tgaaataaga tattgtttgt ttgtggggtg agtaggaata gattggaatt 140640 gtattttttt ttttttagtt atagttgtta ggagtttatt tttttttgtt tttttttttt 140700 gttgtttttt tttataagat tgggttggat gttgttggga aagttaatag gaagtttttt 140760 ggttgtggtg gaggtggggg tttgtgtttt tttggggatt gagatgaggg ttttaggttg 140820 gttttggtaa gagtagggag gtttatgttt ttgtttgttg gttttgtttt ttgttttggg 140880 agaaggtatt tatatgtttt agaatgtatt ttttgtgtgt atagggatgg tttttgggtt 140940 atttatttga ggtttattga tttttttttt tggaattgga gtggtttttt tatggtggat 141000 tgggttgagt tttttgtttt ggttgatgtt tttttttagg tatttttttt tattgtgtta 141060 gggtgtaggt tgttagtgga tgggttttta tttttgggga ttggtagttg ttatgtttat 141120 tttatagttg agatattttg gttgaaggtt ttgttaagtt ttatggagtg tagggatttt 141180 ttttgagatg gttttttttt gttgtttagg ttggagttta atggtttaat gttttgttta 141240 ttgtgatttt gattttttag gtttagtagt ttttttattt tagtttatta agtagttggg 141300 attataggtg tgtgttatta tgtttggtta attttttaat tttaattttt ttttgtagaa 141360 atggagtttt attatatttt ttaggttgaa ttttaatttt tgggtttaaa tgattttttt 141420 gttttggttt gttaaagtgt tgggatttta ggtatgagtt attgtgttta gttggggttt 141480 ttttttaatt ttttttggtt ttttttaggt gtaggatttg ggttttagtt ttatgtgttt 141540 ttgaatagtt ttgggttttg ttttgtattt tttgggtgtg tggttaggtt ttttgtgata 141600 ttagtaggag atttaggtga agaagtaggt agaatggaat gtttgtttat ttagttttgg 141660 ggttaggtgg ggtggttagg atagtagtag tggttggtgt ggttttttgg gaggttagtt 141720 tattggtgtg gttagtgaat ggggagggga gttttttttt ttgttttttt ttatttttgg 141780 tttttgggtt tttagggtta ggtttttaga gttttaggtg gaggatggag gttagggaag 141840 ttggggtaag agtgggttgg gggtgggtgg ttaggtggat tttggaaaat tattttttgt 141900 aggttttgtt ttttttaggg agtatttagg gttggttttg gggagttggg ttaatggtta 141960 ttttggatgg tgtaggggtt tatttttatg aaattgggtt tatttttatg aaattgggtt 142020 tatagaagtt tttggttttg gttttgtttt gttttttggt ttttgttttt aaagtaggat 142080 ttaggatagt tttgaatttt ttgttgaaat gtagtttttt gggttttaat ttagtttttt 142140 agaattagag tttttggggt gggttttttg tttgtttagt agtttttagg ggatatttgt 142200 gtttgttaga gtaagtttaa taagtattgt tgtaaatttt ttgtttttat agttttttgg 142260 tttgtttttt tttttttgtt gggatttgta ttaggattaa atgttaatat tagggattag 142320 gttatatttg tgaattttga gataatattt gtattttttt tttttttgag gttgttttgt 142380 ttgttttgtt atttaggttg aagtataatg gtgtgatatt tatttatggt aatttttatt 142440 tttagggttt aagtaatttt tttgttttag ttttttgagt agttgggatt ataggtttat 142500 attattatat ttggttaatt tttgtatttt tagtagagat ggagttttat tatgttggtt 142560 aggttggttt tgaatttttg gttttaagtg atttgtttgt tttagttttt taaagtgttg 142620 ggattatagg tgtgagttat tgtgtttggt ttgatattta tattttgatt aagttgttgt 142680 ggaaatattg agtttttttt gatagttttg tttatagagt gaatgtttag gaattggtga 142740 ggtatttttt atttttattt agatggtggt ttggaggtag tgtttttgat tttgtgatgg 142800 gatttgtttt ttttgtttaa gagattttag agatgtggtt tttgaatgtg ggggtttttg 142860 ttggggtggg aatgggagtt ggttttggtt attgtttagt gattttattt tagtgttttg 142920 attttagtat ttttgatttt agtgtttttt tttttttggt tttgtgtgga gattatgtgg 142980 tttgtgttga gtaatttttt attgtttttg ttgtgttttt gttgtaggga agttttttta 143040 gggagttagt tgatatattt ggtttttatt atttgttttt gaataggaat gaaaggagag 143100 agtgagtaag aaagtggtag gaggtggggg ttgtagagta ggggaaggtt agagagaggg 143160 gaggaaagat ttggaaagtt taggtatgtg ttttggaagt aggtgttagt gatgagttta 143220 tttggagggt ggttgtttgt tttgagtttt gtttggggtt agtagggaat attttgttag 143280 ggtatgttgt tgggagtttg tttttggttt attttttgtt gttttgagtg ttgagtagat 143340 ttgtttttat tttagggata atgtaaggag gttgttattt tattttttat tttattaata 143400 ttttatgaat tataagtgat tatttattgt gttttgatgt attttaggtg ttgggtttga 143460 agttttatgt gttttatggg atgtatttgt attattgttg tagaaaatgg tttttgttat 143520 tattgtagag aaggtattga ggtatagaga ggttgaggaa ttggttttag gttatatagt 143580 tagaagtggt tgattttggt tgtgaatata gggttgtttg attttaaagt ttgagttggt 143640 ttgtagtgag gtttatggtt tttgtgttat tgtttgagtt tttggttgag ttttttggtt 143700 tagtgggggg tttagtgatt tattagttgt tttattatat gttgtggata tttttatggt 143760 ttatttgggt gggagggaag gggttttagg aggtgggagg ggtataggga atatagttta 143820 gtttgtttgg gtttaatatt ttgattttta aggtattttt tgagggtagt atgaggttaa 143880 gtttttgttt ttttttagga ttttgttttt gtgagggttt tggggttttt tgtttttttt 143940 tgggggtttt gttggttagg attatagaga agttttttgt tgttgatttt tttgtttttg 144000 tattttttgg taagttattt tatgatttag ttgttttgtt tgtaaaatgg gttgaataat 144060 attgttttgt tttggagggt ttttgggagg attaaatgag atttgttgta tagaagtttt 144120 ttgtaagtta tgttgattgg tggttgttgg gtttttaagt gaatgggtat ttgggtattg 144180 agtgtgtgga tttagtattt ggaaggaggg gttggggggt atttagaatt tttgggaggt 144240 ttggattttt gttttgttta gattttgagt ttttttttgg ttagtttaat ttttattagt 144300 agggtgaggg taattaggat ttatgtatag ttgggtgaag ttgagtgatt atatgtggaa 144360 gtttagtgtt ttttatgtaa agtgggtagg tggttaaagt gagttttgtt ttagtttttt 144420 tatttttggg gttgtttttg gtgttttgtt tttttttaga gttttattga tttgtattat 144480 gtgatttggg tttgggaaga tgggtttagt tgtgggaggt tgtgtgggtt ggggattgag 144540 agtgttggag gagggttttt taggaaaatt tagttgtata ggaagttggg ttagtggttt 144600 ttggaagttt ttgggttttg taagttggat tttttagatt tgtggttgtg gggttttttt 144660 ttgtttgtag ttgagagttt ttgatttgta tttgagggtt ttagaggttt gggaggggga 144720 tgtgattgtg tttttagggt gaagtttatt tgagtgttat tttggatata gtttttattt 144780 ttttttggtt ttttttttgg ttatggggat gttgtttggg gggggttttt ttatatggaa 144840 ggagttgtag ttgagttggt gggttttgta tatttttaag gttgtttgat ttttagtttt 144900 taagtggggt tgtatttatt atttaggatt tggagtttta gttagagagg gattttttat 144960 tgtttttttt tttgtttttt gggaaaggta gggtttttgt gttttttttt atttagggat 145020 ttggtatgtt gggaggttaa gaggaagttg ttttttgttt atttattttt taattttttt 145080 agttagtaga gttttatttg tgtgtttaga atttgtgtgt ggagttagaa gttataaggt 145140 tggtttagtt gtgtttgatt ttggttgtgt ggttttggat agttttagtt tttttggagt 145200 tgagtatttt gatttgtaga ggagaggttg ttgtgttggt tttgtagggt tttgtgtaga 145260 ggggagtgtg tgtggttgtg agtttaggtt atgtttttag attggaggat aggattggaa 145320 tagtgggtta ggatggttag agggttttag ttttaggagg aggtttttat attttttagt 145380 atttttatat taggaaatgt agttaggttt ttaggttttt tatgttagga agtagtattt 145440 tgttttttat ttttggttgt ttgggtttga gaagttgagt attttttttg aatttgagtg 145500 ttttttgatt tttgtttggg tagttgtttt ttttgaattg attgtttgtt ttatatagtt 145560 ttttgtggtt tgtttgatag ggtggttagt gagttttttg tatagtatat tttttttagg 145620 agtgttgttt gtgatgatgg tgtaaagggt gtttttttga gtttttggag gtatgtagtg 145680 gtgtaatagt gtgagtttag gagttttggt gagtttttgg atggagaatt tgtttagatt 145740 attttttagt ttaaattttt tttgggtgtt tgttgtgttt ggggtgttga tttattgtgg 145800 ggtggtttgt gagattttat gttatttggt tatttttttt agtttttgtt tattgtattg 145860 gttttttggt ttggttgttt ttggaatatg agggtttatt tttatggaag aatatttatt 145920 tgtttttttt tggaaagttt ttttttagat tttttggttg ttttatttag gttttgttga 145980 agtgttgtta ttttggagag gtttttttgt tatttgtagt taaaatagtt tttttatgtt 146040 tgtgggtggt tttttatggg gtatggatga gtattggaga gttttgttgt ttatttgttt 146100 atatgttttt tgggagggta ggggatattg atttgtgttg tgggtgtttt gtatgttatg 146160 ggtgtttagt gaatgtttgt taagtattag gggagtataa aggagggaag tttttgttta 146220 attggagtag ttagggaaga ttttttggag gaagtggtat ttggtttgtt tagaatgtgg 146280 tgatttgttt gtatgtagat attagattag agggtaaagg ttattattat aatttagtag 146340 atagttataa gtagttaagg aattgttatg atatggattg tttgtgattg gagttaagaa 146400 ggagttagag atagaggttt ttgtgttttg gtgtgagttt ttgggggagg ttgagttttt 146460 agaatgtggg gttgtttgtg tagaggttgg aggtgggaga tatatttgtg agtgttggtg 146520 agtgtggggt gagttattgg ggttggatta gaagatggga atttttaaat ttattaatta 146580 gttttggtgt tttgggagtg ataggagatg gggtttttgg gggattaatt tagtataagt 146640 ggatgagatg ggatgtaggg gaaaggataa agttttttga ggttttggga agttgagtta 146700 gggtagagtt atgatagggt gagttttaga agtaatataa gaaaaaatag ttagattggg 146760 tttttttttt attgtgggag atgttttatt ttattttttt tgttttttgg gttttggtaa 146820 tgggttgggt atagtgaatg ggttttattt gtaggagtgg ttatattttt tgggtatagt 146880 tgttttatat attgtattga gatgggattt gaggttggga agaatagttt tttttgtagg 146940 ttgatattgt tagtttttgg ggagggaagg atggtagggg gtttggagta tttttttttg 147000 ttatttatat tttgtgtttg tttgtagggt tttgagtttt gtttgttttg ttttagtttt 147060 ggttaggaat ttgttggagt ttataggggt agttaggttg gaataggagg agattaggtt 147120 ggtaggggag ttgagagggg gttttggata gtatttaggg ttgagttatt ttgggtttgt 147180 ttgatttgtt atttggagtt gtttttgttt gtttattatg tgtaaggttt tgatttattt 147240 gggtttgttt aattagtgtt tttttttagg tttagttagt ttggtttttg tttgatttat 147300 ttattgttat tagtgttatt tttgtattat gtaattagtt tttgtagtat gttagttatt 147360 aagtttaggg ttttttgtgt attttttgta atttttatag taatttggga ggtatagaga 147420 ggttgagttg ttggtttata gttatatagt aggtatgggg tattgttagg atttagttgg 147480 atttttgatt ttagggtttt tttagggttt tgggtgggat attggtaagg aagtaaggta 147540 tgaatattgg ttttgttttg gatagagttt ggggatggtg gtttggtagg tttagttgat 147600 atagtgattt tggtgtaggt ttaattattg gtaaagtgtt taagtatata tagaatttta 147660 attggggaga taggtgaagt ggttaaggga gggttgtgag tgataggtgg atattgtatt 147720 tattggtaga ttagttgatt ttggtgtttt ttggagtttt ttaatttttt tatttagaaa 147780 aagaggaatt aatagtttta tttttaaatt gggtgggagt attatatttg aaattgaagt 147840 aaagttggtt gtgttatagg tttggtagat gttagttgtg taggtaattt agtgattatt 147900 tgaagtaggt tgtgtggtgg tatttttatt ttgtagatgt agtttagaga ggttagggta 147960 ttaattttgg gttatatagt gatagtttag gttatagaga gtagtgttgg atgggagggt 148020 gttggtagtt ttaggtatag gttgggaggg ttgtggggtt agtagaggga gggtatattt 148080 tttagttggt ggggtttttt tgtgttttag tatttatgtg ggtttaaagg agttggaagg 148140 agggaggtta gagttattta tgggtttaga agttgataag taggttattg attttgaatt 148200 tgttttattg tatgtaaatt ggggataaat ttggggattt aatgatataa tgtaagaagt 148260 agatatgtta tagttttggt tatatagtta gtgtataata agtggtaagt tgttagagga 148320 ggtagttggt gagaatggga gtattttagt agttttttgt tttttgtttt tggttgtaga 148380 tgtatttgtt tttggttatt tgtgttttag ttttgtgttt tttggtgtgt gtgaggttaa 148440 gtttttgggg tggggatttg ggggtgtgtt tgtagttttt gaggttaaga ttaaggttga 148500 ggttgaggtt gaggttgagg ttattttggt gaggaggaaa ttgtaggtgg agaagtttgt 148560 tgattgtgat tttgatttga ttgtaatttt gatggtgttg atgttgttag tatgtaggtt 148620 ttttgttttt gttatgattg gtttttgtag tttatttggt tgagaggtgt gttggttttt 148680 gtaggttgta aaatggggat attattgttt gtttgggtta tagtgtgttt gttgattgta 148740 tttggggagg gattgagggt tgattgtgtt gtggggatgt tggtagagaa ttagagaggg 148800 tatttaaaaa ggttaatagt ttggtgggga gaggaggtgt aaggttggtt tttgtttttt 148860 gggttttgat tgaaagggaa taggggatat atttggggat agtttttttt ttggaggaag 148920 aagggtttag ggtgttggtg tggagtttgt atagatgggg ataatgagtt ggagggtgtt 148980 gggtaggagt tggttagtaa taggttgatg agggaggttt tgttggttgg gtttggtttt 149040 taagtgagta ttttgagttg tggggattta gggggtttta gagattttag agttgagatt 149100 tgggattata gaggggtggg ttgtgtttag ggtaatatag tggatggggt agatgttgtg 149160 aaatttgttt ttttgttttt tttttttttg ttatagaatt ggattttttt agtttatggt 149220 tgttaaattt tttagatgtt tttgggtttt atgggtgttt tatattggtt tttttgtagg 149280 atagtagatt ttgggggttg gttttgatgg tatttattat ggggtatttt atgtaagtat 149340 agtgttttta tgtttagttt tttagtttgt ggagtaggtt tgtgtttggt tagttttatt 149400 ttgtggttag aggagggaga tagtggtttt ggagatagga gttggtttgg ggttgttttt 149460 ttagtttttg tttttttagt ttattttttt gttttgtggg tgttggttat tttttttttg 149520 ttagttttat ttttagtttt ttttgtttga gttgtgattt gttagtaggg ggtagtggag 149580 gttttgaaag tttttggaga ggattttgaa gtagttttta taaatttgtt tttggaaagt 149640 tttttttgtt atatttttag tggttttttt ttttttaata ttttttttgg ggttgttatg 149700 tagtgggggg tggaggaatt tattaggttg tggatagagt agagttatgt tgatataaat 149760 tttggttgaa tttatatgtt ttttatagtt agtggttgat tattggaatt agggaagtga 149820 ttttatagta agggtttgta gagtagttat tatgtatttt tgattttggt ttttggattt 149880 agttttggaa aagaagttag attttagtta tttggagttg tttagggaag attttagttt 149940 ggtgttggtt gatagtttat tggaattttt tatttgtttg gttaggtgat gttaaggggt 150000 agaggttaga agtgttaaga agtaggttga gggtggtggt ttatgtatgt aattttaata 150060 ttttgggagg ttaaggtggg tgaatttttt aaggttagga gtttaagatt aggttggtta 150120 atatggtgaa attttatttt tattgaaaat ataaaaatta gttaggtatg gtggtgtatg 150180 tttgtaattt tagttatttt ggaggttgag gtaggagaat tttttgaatt tgggaggtag 150240 aggttgtagt gagttgagat tgtgttattg tattttagtt tgggtaatag agtaatattt 150300 tgtattaaaa aaaaaaaaaa gaagaagaat aagaagtgtt aagaagtatt tgtttttttg 150360 attgaaaagt aatttttgtt gggtgtggtg gtttatgttt gtaattttag ttttgggagg 150420 ttgtggtggg agagttgttt gaggttaggt gtttgagatt agtttgggta atagaggtgt 150480 taggggtagt ggtgtttgtt tgtagtttta gttttttagg aggtttaggt aggaggattg 150540 tttgagttag gagtttgagg ttgtagtgag ttatgattat attattgtat tttagttttt 150600 gggtgatagg atgagatttt gttttaaaaa ataaaatata aataaaaaat taatgtttat 150660 tttttgtgat tttaaaaatt atatttattt gtgataaaat aattaaatta gaaaatgtaa 150720 aggaaatgat taataataat tgtgtttttt agataaatat tgttaatatg tttatgtttt 150780 tttttagttt ttttttatat agatatttaa tatttattaa tttgttttga attaaagatg 150840 gttttttttg ttttgtatga gaattatttt agttaggtat ggtggtttat gtttataatt 150900 ttagaaagtt gaggtaggta gattgtttga gtttatgagt ttgagattag tttgggtaat 150960 atggtgaaat tttattttta taaaaaaata taaaaattag tttggtgtgg tggtatatgt 151020 ttgtgttttt agttttttag gaggttgagg taggagaata gtttgagttt gggaggtaga 151080 ggttgtagtg agttaagatt gtgttattgt attttagttt aggtaatggg agtgaaatgt 151140 tgttttaaaa aaaaaaaaaa aaaaaaaaaa gttgttatgt tgttattttt tttagggatt 151200 tttatttttt ttattttttg tttaagattt gttttgtaaa aggatgaggt taaatagtta 151260 tgggagggtg gtattggatg tttaaaaaaa tgttttgtgg ttggtgggat ttagaaatag 151320 gttggggagg ttttagtaga gggtggattt tagttggggg tggggggtag taggggggtt 151380 ttttatatgt tttttttgtg tgttttatgg ggttgtttgt gaggttgtgt gaattagagt 151440 ttggttggga agttatatgt tatttggatt ttgatttttt ttggtagtat gattttagtt 151500 aatatgttta attatgtttt tttttgtaaa atgggttaat agaaatgttt atttgagata 151560 tgatgagaaa taaaggtgtt tatagagtaa agtgtttaga atggttttgg tatgatagga 151620 gtttatatgt tagtgttgtt gttggtattg ttattattat ggtggtattg gttgttttgt 151680 tttttttttg tttttgttat tttttttttt tagtaggttt ttatttattt gtttatttat 151740 ttatggttga ggttttgttt gtgttaggtt tggtgttgag aatgggggta gagagatggg 151800 ggttgtgttt tgttttttga tttaagggtt ttttttgtaa tgtgaagttt ttggagattg 151860 gatttttagg ttgttttatt agtttttttt taggttagtt taattttttt gtgtttgttt 151920 tttgagttgt tagaggaaga gagtgggagg aaggatggag tggggttttt gtggggattg 151980 agtggggggt gtgtgaggtt ttggaaatgg tgtttgtggt atttatgtag tattagtttt 152040 tgttgtagtt gttgtttgga gaatattttt ggattttagg atattgatga tagaaggtgg 152100 aatgtttttt ttggaagtta ttaagagggg attattgtgg tggttgagta gagttgttga 152160 tttgtgagtt gtggtttgat tatagttatt gtttttatga gtgaggtttt ttgtggtttt 152220 ttttttagga atttttggtt ttttggtagg ggatagttta gggttggggg tgggtagtgg 152280 tgtttgtagg tttttttgga gttagagaat tttttgttgt tgtggtgggg ttgttttttt 152340 ttgttttttt ttttttgttg tgtttttagt tgttttgata ggatgttttt ggtttgagag 152400 atagaaattt taattttgaa tggttttagt ttttaagaga atttggagtt tttttgtgta 152460 aaatgagatg ttttgagtat tgaggatgtt gtgggggatt ttttatttta ttatttttag 152520 ttgtggtgtt ttttttggtt ataggatgtt gtagttatgt tgtagggaag gagagttttt 152580 ttttttgtga gtttagggag tttttttatg tagttttttt attggttatt gtttgagatt 152640 tgatttggtg gtttttgttt taaggagtag aaagggggtt tgttaggtta gggtggggtt 152700 gggtgtgagg attttttttg gttaataggg tttgtttagg tgtttgtttt gttggggtag 152760 tagggaaggg atttatatgt ggtattggga tatggagagg tttttgtgtt tgtgatggtt 152820 aaaagggatg gtgttttagt tatgttttta tttattttga ggtttagtat ggttatgttg 152880 gaaatagtag tattgttttt tttattgttt tggtttgttt ttaataggtt agaggggtgg 152940 ggttggagtg ggtgtttgat ttgtggttgg atttagttgt ttgtggatag gttgtgagtg 153000 aatttgtaga ggaagggaga tgggaatgtt gggatttttt tttgtatttt ttgaattttt 153060 gttttttgtg agttagatgg ggagtgtatt tttgtttttt ttttttgggt attttttgtg 153120 ttttttgttt taggtatttg atgttgtttg tttatttttt ttttttgttt tttttgttgg 153180 ttttttttat atggttttaa ttaggatttt ttgtttgttg gtggatgggt agagagggga 153240 gtttgttgtg gggttttttt tgattggggg attttttagt atagagtttt ttggtttttg 153300 tagggatgtt gtgtgtgttt gtgtgagttt ggtgtgttag aagtgttaag ttgtagttgt 153360 tttgtgtgtt ttttatattt tttatttttt aaaggttttg ggtttggtgt ttgtgggttg 153420 gggatttgtg ttggggtttt taggaggttt ttggtgggag aggtagggtt tttttttttt 153480 taatttgggt aattttgttt tggtttgttg tttgtggaaa gtgttttagg atatggtggt 153540 aggattggtt ggggttttgg ttttaggttt agttttagtt tttgttagat ttattttttt 153600 tgtgtttttg tttattttgt ttatttgtag ggtttgtagg agtattttga gagttggtag 153660 ggtggtttgt ttggtgtttg tatagggttt gttggtgggt ggttgaggtt gtggtgaggt 153720 ttttatggtt tttttgtttt gtatattttt tttttgttgt gttgttttgt tagtatatga 153780 gtttgtattg tttttgagtt tgtagtttgt tttttttatt aggtggttaa gtagggtggt 153840 agttagggtg gtagagtttt attggtttgt aggggatttt ttgtgggttg taggtagttt 153900 tttgtggttg aaggtgtttt ggtaggattt gtattatgat ttttgttaaa gtttatgttt 153960 aaggtatttg tgggtatttt tgttttagat gtgagggttg gtattttttt ttgtatgtga 154020 agtaaaggtt tgtttgaagg agtgtgtgga agtttgggtg tgatgaaggt aaggattggt 154080 ggtttatttt ttttgtattt ggattttggg tggtaggttt ggggttttta gtttttaatt 154140 taggagggta gttagttgtt ggaattaaga gtgaatttta gttgttgttg ttatagttgg 154200 agggaagagg ggaaaggagg tgttgtaggg gagtagagat tttatttttt ttttgttgat 154260 attaggttgt tggtgttgga tggggttttg gtaattgtgg taggagtggt gatgtttgat 154320 gatggtaata agggtttttt gaggattttg agttgtttta agggtttttt atttggagta 154380 agtatttttt ttaatttttt taataatatt gtgaaattga ttttgttgtt atttttattt 154440 tattgatgag gaatttatag tttagagatg ttaagtaatt tgtttaagtt tttttttgag 154500 tatggtagag ggagggtttg aatgtggaaa gtttggtttt agtgttttta tttttaatta 154560 ttgttattta tttttttggt tagttttttg attgtaaaat ttgaggttta gaggagtgta 154620 gtgatttggt tagttttgta tggtaggtta gtggtagagt tgagtagtgt tttttatgtt 154680 ttgattttgt ggttttttga ggtggtttat ttttaaatat gttttttatg gtggttttgt 154740 tttttttttt tttttgaatt tgttagtttg tgtttaggta gggggagaag tagagtaatt 154800 atgttgggtg ggttgttgtg ttttagtgtt gtttgtttta tatttgattg gtagtagagt 154860 ggtttttttt tggtgtggtt tggaggtgtt agtggttatt tattagtata gtttagtttt 154920 atatatgtta tttttaaagg atgttgatat agaatgaagt agttagggga ggtggatgtt 154980 ttggtatgag ggtggtgttt ttggtaattt gtagtgttgt tgtttgtggt tgtttttggt 155040 tggtatttta tttttttttg gttgttttgt agttatttga gggaggttag tatgttgttt 155100 ttattttagg atagtgtgaa tgtagtagtg taagtttgtt agtgttgtat tgtgggattt 155160 ggaggttttt gtttttgagt tttgtttttg tgtaattttt aaagtatgga ttttttaggg 155220 gtttttattt ttttatttgg aaaaatttta tattgtttag ggtttgaggt agggttagag 155280 tatggagatg ttgttggagg attaagggag aattgagtgt gtgttttttt ggttttagtt 155340 ttgtgtgtgt gtttatgtat gggtattttg ttatttatat tggtttttat ggttgggtgg 155400 gagttgagtt gagtttggtg gttgtttttt tattttgtgg gtttggttgg ggagtgtgag 155460 gatgtttgtt ggaagttaat gtgtatgaaa gagttaatgg tggattttat ttttttagtt 155520 ttttttttag tttttttagg gaaagggtag gaatagagag gttttatttt tagaggaagg 155580 ggtgggtggg gatatagtgt tgtttggtat agtttttttt gagttatttt gtatgtttta 155640 ttttattgat ttttgtagtt tagttgttta gagtggattt agaaggtgga gagagggttt 155700 ttaataagta gaggatggag tgaatgtgag atttattatt gggatttggt aaagtaaaga 155760 gttttatttt ttttttgtag atgggatggg ggtggggttg gagttagtgg ggtgggggta 155820 tttagtaaga gttttttttt atttttttat tttttttgtt atgggttttt ttttttatgt 155880 agatttttag tttggaatga ttagtgttta gttttttttg tttttttttt gttttgttgg 155940 agggagtgat ttggtttttg gttttggtta tttatatttt ttgttttgtt gtattagttt 156000 tgtggtaggg gttgtggtgg aggtgggtaa aagttgtttt tgggtagtta gtttttattt 156060 tgggagtgat tgaaagtttt tgggggtttt tgtagggtga gttgtttatt ttggttttgg 156120 taaggatatt taggagaggg ttagggtgtt tgtatttggg gtatagtata aagaatagtt 156180 gtaagtgttt tttaggtagg agggtgttga agtattggga agttgggatt tagaagtatt 156240 gtttggggtg gtgagtggaa gatgtaggat atagatttat gtgattgtgt agattatttg 156300 gttttatttt tttggtttat agtggaggaa attagaggtt gagagaggtg aagtgagttt 156360 tttggggtta tatagtttag ttaggtttag ggtgttgatt ttttgttttg tttttttgtg 156420 tttatttggt tggtattagt atttttgttt tgatattttt gtgtggtagt tgttgtgatt 156480 ttgtgatttt tttttatttt attttagtgg ggttttgtga gggaaagaag aatgttttat 156540 gtagaagtgg ttggaaagta agaagtttgg agagaagtga ggtttttgtg gtttggtttg 156600 agtttaggat ttatggtttg gtttttaggg atggagtatt gatttttttt ttttatattt 156660 ttattttatg tttttaggag ttttttatgg ggaagttgga atggatttgg gtttagagat 156720 tgtaaattta ttttgttgga tgtgtggttg tttttatgta attaattttt ttatggagaa 156780 gttaggggat ggtttttagt atttttgggg gttttttagt gaggtgggag gattttgaga 156840 ggttaggagg ttgtttaaga ttttttgttt tttagggatt aggtgagggt ttgttgattg 156900 ttttgatttt ttgatgtttt tggtggggag attttagagg ggtttgttgt tattattgtt 156960 agtggttttg gtttgtttag ttattttttt ggggtggtta aattttatgt tgtaaaagtt 157020 taagtgaatt ttagtagtgg tttgggagaa ttatttgtta tgagttaagg atggagtttt 157080 tggggaggat tttttgttgt tttttaattt tttttgggta tatttttttg tagttttatt 157140 ttttgtaaga aagttaggtg ttttttgaag tttttttttg gttttaggtt agaggtgata 157200 gtgggggttt tttgtttgtg ttggtgattg tggttggttg ttggtgtttg gttttgtttt 157260 gtattgtgta tttattgaag gtggtattat ttgggttttt ttggtggtta tgtatgggtg 157320 agtagtttat gatatatttg tttttagtat tgtgtgggtt ggggttttta gaggggttga 157380 gggtttggat ggttttgtag gggggtgttt ttggttttgt gattgaaagg agttgaaggt 157440 ttggagaagt tgttgggttg aggttagttt ttatagattt ggtgaggagg gaatagatgt 157500 ttatggagtt gttttaggta ttgtatatat tgttttattt tgtgttgata gttaagaggt 157560 tggttttttg ttgattttta ttttatagat aatgtgtttt tttagttttt tagtggtgga 157620 gttaggattt gaatttatgt aggtagtttt ttgggtttgt agttttattt tttatttttt 157680 tttaggattt atgttttggg gttggtagga taatgatttt tagagttgag tatattttaa 157740 tttttagtat ttgggattat gttaggtgat atggtagggt tagttaaggt tattaattag 157800 ttggttttaa aatagggaga tgattttgga tgatttatat gggtttgttg ttattataag 157860 agtttttaaa agtgtaatag attatttgag gggtgtagtg ggagaggttt ggaaggagga 157920 aggaggttat aagttaagaa atgtaggtga atagaaaatg taggaaaatg tagttttttt 157980 tgtagttttg ggagggtgtg tagttttgtg gatatttttt ttgtagttta gtgaggtgga 158040 gtgtgggatt aatttgtgtt gtttgatatt ataagtgtgt ggttatttgt tatagtagtg 158100 atgggaattg aatgttatta ggtagtagtg tttttatttt ggaagaatta ggataaattt 158160 ttttgtggat tttaagtttt gggagatttt gggttttttt ggattgtttt agttttgtaa 158220 ttataggaaa ggttttttat gtttgtttgg gagaagaaaa ttttgtagta aatttatttt 158280 tttttttgat aaatgaaggt gagggtgtgg gttggatata tgtttttttt ttgtggattt 158340 tttttgtttt aatatttaga attttgtagt tgaaggagat tttggggggt tgtttgtttg 158400 atttgtaagt gaagaaatgg aggtttaggg aagttaagtg attggtttag ggttatgtag 158460 agttatgttg gaatattaag ttagatagtt tagtttttgt tttaaagtgt tttttttttt 158520 ggttggggag gagggttgga gggagtggat tttgagtaat agtagtattg gtaggggttg 158580 gaagagtagt tattgtattt aggtgttgga gtttttggtt attttttgta ggaattaggt 158640 gatttattat ggtataggtt tttttttgtt tatttgtagt tttgggggtt ttagggatta 158700 gaggatattt tggtttgagg gttggggttt gagagaagag atggaagtat ttttagtttg 158760 gtttgttttt gtggtgtttt gtaggtatat ttggtagttt aggggtttta gagaatttgg 158820 ttggtgggtg tttttatttt gttgtagttg tattttgtgg ttagtagttt gtaggatttg 158880 ggttgttgtt tgtggttttg aaatagttat tttttgagtt gagtggggat taggtgagta 158940 gatttttata ttttaattgt tgtgattttt ttgttttgga ggttggtggg tagtttggtt 159000 ggtgttttat ggtattttat gattggtttt gttattaggt ttgtgagttg tttttttttt 159060 tttgggtatt ttgaatggtt tttttgagag ttttgttttg ggtttttgtt tttgtaggtt 159120 tttgttgttt ggggtgtttt ttttttttgg aagttgggtt tttttgggga tttattaaga 159180 agggttttgt tgagtgttgt taaattgttt tatttggttt ttatttgttt tatttattat 159240 tttattttaa tttttatgtt ttttttttgg ttttaagatt tgagtaggta gggtttgtga 159300 ggtattttag gttttttgat gttgttagta tttaggggat tgttagtata tatgtaggga 159360 gggaaggaat gaaggaagag atgatttggg gagtttttta gtttttattt gtaattggta 159420 tattgtgata aaatatttat ggtattttat tttttttata tatttttttt ttaaatttat 159480 ttttatttga gatggagttt tgttttgtta tttaggttgg agtgtagtag tataattttg 159540 gtttattgta atttttattt tttgggttta agtgagtttt ttgttttagt tttttaagta 159600 gttgggatta taggtgttta ttattatgtt tggtgaattt ttgtattttt agtagagatg 159660 gggttttatt aagttggtta ggttggtttt gaatttttga ttttaggtga tttgtttgtt 159720 tttgtttttt aaagtgttgg gattataggt gtgagttatt gtatttggtt tttgtatatt 159780 tataaaagag aatttgttta gaaaattttt tagatgtatt tttagggttt taaggtatag 159840 atatatgaag tttgttagtg agtagttgtt gtttattttt tttttttttt taatttagag 159900 tggtttgtgt tttaagtgga tagttgtttt tttttttttg gttttttgtt gtttatgttt 159960 ttatagaagt agggagaaga ggtaggaagg tgatgtgtga ttatttgttg ggtgtttgta 160020 tagtgttgtt tgtataggtg ttattttttt tatttgttat tttttttgtt gagttttttt 160080 ttttttttgt agatgagaga gtattgtttt ttagaggtta agaaatgggt ttagagttat 160140 ttagttgatt agtgtgtagt tagatttgaa ttatattttg ttgattttta tgtttgtagg 160200 tttggtttga tgagatggat agttgggtgg tggagatttt gagattttgg atggttttta 160260 aatagggttt gtagtttttg gatagggaga gtttggtata aagggtttgt ggagtgagtt 160320 gggggagaag gtggtttagg gtttttgttt ttgaataaat agatggaggg gttattttag 160380 tgttttttta gtttttggtg tgttgggttt ttggttttgg gaggagagaa tggagttggt 160440 ttttattttg ggttgggttg gtttgggttt aatttagata agttttttag tttgttatga 160500 gtgatatttt tgtttgtttt ggtgtttttg ttaaaaatat gaagggtttt agaattttta 160560 ttttggtttg tttttttttt agatttggag tgggtttggg gttgataata gttttatgtt 160620 agatagtttg agtagttatt agtgttatta ggtttgatat tgtggttttt gttttggagg 160680 gaaaaataag gttttttttg ggggattttt tgttagtttg tgaaaatagg tttggagtta 160740 gttagtgttt ttatgtttag atattttgtg tggtttttaa agtgttttta tgttgttagt 160800 ttatatgatt ttttttaaaa ttttataagg gagggtagga agtttgagta atagtttgtt 160860 aagtatttat atagtaggtg gttttattgt tttttattta tagataagta aattgagttt 160920 tagggtggtt attgtttgtt ttttaagtta tttagttatt tagttatgga agaggttatg 160980 attttttata ttttagtgaa gttgaagatt tttttttttg tttttaaaaa tgtttatttt 161040 ttagggtagt gaatatttgg tgtttttgtt tagtgtaaga ggtgaatgtt tgttattttt 161100 gttttttttt ttttattaga tttgattttt tttttgtgat gggaatattt tgtaggtagt 161160 ttgttttgtt tttatagatt ttgagaaatg gggtttaaat tgttggttgt gggtgggata 161220 ggtgatattg tagtgaagag gtggagtatt tttgtagtgg ggaagaaata tatttttttt 161280 atttttttag gtttagtgtt tgggggtttg tgaattaaat ttatttaaga taaattaatg 161340 agagaaaaga tagatttaat tatatatgta tgggatttta ttgaaaaatg tgatttaaaa 161400 gagtaggtag aaggtggggt ttgtgattgg tttgaaggta gtgagttatt ttagttgatt 161460 gtttatagtt agttatagat tagatttttt gttttattgt tttttttttt tttatttgtt 161520 ttgttttttt tgagttagag ttttgtattg ttgtttgggt tggagtgtaa tggtatgatt 161580 ttggtttatt ttaatttttg ttttttgggt ttaagtgatt tttttgtttt agttttttga 161640 gtagttagga ttataggtat ttattattat gtttggttaa ttttttgtat ttttagtaga 161700 gatagggttt tattatgttg gttaggttgg ttttaaattt ttgattttgt gatttgttta 161760 ttttggtttt ttaaagtggt gggattatag gtatgagtta ttgtatttag ttaattagtt 161820 ttaaaaaaaa aaaaaaaaaa aaaagaattt agggtttgta tattatttta ataggaaaaa 161880 aggaaggggt gaaagtatat attatgggtt gggtgtgatg gtttatgttt gtaattttgg 161940 tattttggga ggttgaggta ggtggattat ttgaggttgg gaatttaaga ttagtttggt 162000 taatatggtg aaattttgtt tttattaaaa atataaaaat tagttgggta tggtggtgta 162060 tatttgtaat tttagttatt tgggaagttg aggtaggaga attgtttgaa tttatgaggt 162120 ggaggttgta gtgagttgag attatattat tgtattttag tttgggtaat agagtgagat 162180 tgtgttttaa aaaaataaat aaaaaaaaaa aagtatatat tatggtaaaa taaatgagtt 162240 tttggaaaga taaataggtt tttaggagtt gagatgggag atgtgaagtt ttgtgataat 162300 gtttttttag gtgtggtgtg gaaattattt atatttttta gggaagagtt agttgttttt 162360 agggagtaga tttgggtttg tatattattt taatagggga aatggaaggg gtaaaagtat 162420 atattatggg ttgggtgtaa tgtgtttagt gtaggaggta gatgtggttt atggttgttg 162480 ttgaaattag tgtagggttt gattgttttg tattgagtgt tgaggatttt ggttttgtat 162540 tagttatgag tttgtagttt tgggatatat ttgatgttgg tttaagggga aatgaggttg 162600 gaggggtagg gtggttggat tggatgtggg tttggggtta ttgttgattt ataaagtggt 162660 tattatatgg gaataataga gttggttata gattataatt agtaatatta tttaaaagta 162720 aggttatatt tttaataata agttatattt taagttatta ttaatttata aaatatattg 162780 ttggtataat gatagttttt taagaaggat ataaaaaggt atgttgggtt gggtgtagtg 162840 atttatgttt ataattttag tattttgaga ggttgaggtt ggtggattat tttaagttag 162900 gagtttgaga ttagtttggt taatatggtg aaattttgtt tttgttaaaa atataaaaaa 162960 aaattagttt ggtgtggtgg tgtatgtttg taattttagt tatgggggag gttgtggtag 163020 aagaattatt taaaatttgg gaggtggagg ttgtagtgag ttgagattgt gttattatat 163080 tttagtttgg gtaatagagt tagattttgt tttaaaaaaa aagaaaaaaa agaaaaaaag 163140 taaaaaggta tgttgaaggt atttgtttgt ggaaagttgt aatttgatgg gaggtagggt 163200 gagtattttt tagaaaggtg gaaatgggtt tttttgttat agagatttat aaatatagat 163260 tgaggtttgt agtttaggag atttaaaaga ggtaaaggtg aataagagtt aaggttttta 163320 agttagggtt tgattttggg ggtgggggtt atatatgatg gaggatgtta ggagggtttt 163380 ttggaggtgg tgatatttat taggggggat tttaggtggg gtttgtgaga tagtaggatt 163440 tggttgaaga gtgtaggttt tttagatagg agtgggaatt taggtttgaa aatgagttgg 163500 ttagattgta ggggtttttg aatgtaaggg aagaatttta attttaatag aggagtttgg 163560 gaagttgttt gggaaaagga gtgataaagt gggaggggtt ttttagtaga gttttgtatg 163620 ggtaggaggg agtgagatgg gaggtgggtg ttggtaaggg atgattttag tggtttaggg 163680 gagtagttat agggtggaaa ttaattttgt ggggtttggg taggaaggga ttgatttgag 163740 atattgggaa gaaatagtta gtaggatttt ggtgagaggg ttgggggttg gggagggggg 163800 tgtggagagt gggagtttga gtttttgaaa atagatagtg ttttaagggg gagatttgag 163860 gtaagatgtg gagaggtagt tgagttggga agttggaatg gaggtgtggt tattttagga 163920 gattaagtta gggggtgagg ggatttttgg gagttattta gattttagta ttagggaata 163980 tggaggggag aaggagggga gaagaattag ttggtgtgtg ttaggtattg tttttgaggt 164040 tagatggggt ggggttggat attggttatg aggatttttt taagagttgg gttaatagtg 164100 agatgggtgg atattagatg gtttgggtta agaagtaagt gggtggtggg aagttagaag 164160 ttgtggtgta gatttatttt gagaggttgg gttgtttaga tagggagaaa gtttatagtt 164220 tgaggaggta gataggttaa aggaagaggg tttgtttgtt tttgagattg gggtattttg 164280 aatgtttttt taggttaagt gagaagaaat tagaagagga atatgttatt taaatgtgtt 164340 gaaatagttt agtagttgtg ttgttttata gaaaatgtgt agaggttttt ttgttttatt 164400 atgtttgttt ggggatggtt tttatttggg ttatttaggg tttttttagt ttgttaattt 164460 aagggtggta ggagttgtgg gtgtttttag ttttttttta aggttggttt gtgggtagaa 164520 atgtgggttg ttttggggtg ttatagttat aaatgtatat tagtttttag aattatattt 164580 ttgtttttta gttttttttt ttgtattttt atgtagaagt gtggttgtta gtttataaag 164640 gatagggagg gatattgttt ttggtatttg atgggaagta tttgttgtat tttattgggg 164700 tgttgtttag gatggattgg aaaagagttg gtaggaaggt tgagttttgt gtttataatt 164760 tggtttggtg gtggttgagg agtttggtag gagtagagtg taggatttgg gaattggggg 164820 ttggtgtatg tgtgtatgta tgtgtgtgtg tgtgtgtgtg tgtgttgggt gggtagggag 164880 gaagttgtga aattatattt tttttttttt gttgttgtgt tgttgtgtgt tttagtagta 164940 tgtgggtgtt attatatttt ttagtaggtg ttaattttta agattgtttt gggttttttt 165000 tttagttggt tgagttggag gtgggagttt taattgtttt ttgtggtttt tagagtggga 165060 ttttgttgtg ggataggttg gttaatggtg tttttttttt tgtgattttt ttgttgggtg 165120 ggttatgagg aaggattgtg ggtgttgttt atagataggt ggatatgtgg taaggatatt 165180 ttgggatttt ttttttgatg ttttttgaag ggggtatttt tttagttttg agatgagttt 165240 ttgtggatgt gggaagttta ttattttaag agtagtagtt ttggaaaatt taatatagaa 165300 ttttgagtag gggtgggaag gggttttgtt ttgtttattg gttgtttggt agagttttgt 165360 ataaggaagt gtttgtgttg ttgtgggtgg aggaatggat tgagggttat atttgttttt 165420 tgttgttgtt gtaattgttt attataaatt tagtggttta aagtaataga ggtttttttt 165480 tttatagtgt taagggttag aagttgatta gttttattgg attaaagtta aggtgttggt 165540 agaatttatt tttgtttttt ttagttttgg gtgggaggtt ttgttggagt tttttggttt 165600 gtggttgtat ttttttagtt tttgttttta tttttttata gttttttttt tttttgtagt 165660 tagatttttt tttgtttttt tttttttttt ttttgagatg gagttattta ggttggagtg 165720 tagtggtata attttggttt attgtagttt ttgttttttg ggtttaagtg atttttttgt 165780 tttagttttt tgagtagttg ggattatagg tatgtgttat tatatttggt taatttttgt 165840 atttttagta gagatagggt tttgttatgt tggttaggtt ggttttgaat ttttgatttt 165900 aggtgatttg tttgttttag ttttttaaag tgttgggatt gtagttatga gttattatat 165960 ttggtttgtt ttttttttaa aggatgtttg tgatttgggg tttatttggg taattttttt 166020 attttaatat ttttagttat atttatagag tttttgttgt tatatgaggt aatatagttt 166080 gggaagggag agttatttag tttattttag gggtttgtgg tgtattttag ggtttttttg 166140 attttaagat ataaagtaag aaaataaatt ggtttaaggg gaaaaaagga tatgttgaat 166200 tttgttgttt taaatgtata tttttttatt gtgttaaaat gtatagaata taaaatttgt 166260 tattagtaat attgagtata tttatagtgt tgtgtaatta ttagtattgt ttagtgttag 166320 aattttttta ttattttaaa gggaaatttt gtatttatga aggatttatt ttttatttgt 166380 tttttttagt ttttggtagt tattagaatg ttttttgttt ttataaattt atttttaata 166440 agtgtaattt tgtgtgattt taaaataaat aaatatgagt atgatgagtt gtttattgga 166500 aggatattta tgtggggagg ttggtgtgtg gagtgtgtag gtttttggat gggtaggagt 166560 tgaaggggtg tggatgtgtt gttttttttt ttttttgttt tttttttggg gttattgttt 166620 gagtattttt ttttgtaaat ggttttaaat aatgttttag tttttatgtt tgtattgttt 166680 tttagtttta ggatttttta ttaaaaaata ttttaagttt tagatttatt tttgggaaaa 166740 ttttaatggt tttatttttt tttttgagtt agttagattt tatggtttgt ggtgggttgt 166800 ttttgagttt tgagtatttg tgagttaggg aagtaggata ggtatattta gggaagggga 166860 agagttgttg ttagttatag taattgatat ttttggaatt gtttaagaga tatttagtgt 166920 gtgtttaaaa tatttatttt tttttttgtt tgttttttga gatgaagttt tgttttgttg 166980 tttaggttgg agtgtagtgg tgtgatttta gtttattgta attttttttt tttgggttta 167040 agtgattttt ttgttttaat tttttgagtg gttgggatta taggtatata ttattatgtt 167100 tggtgaattt ttgtattttt agtagtgatt gggttttatt atgttggtta ggttggtttt 167160 gaatttttga ttttaggtaa tgtgtttgtt ttggtttttt aaagtgttgg gatgataggt 167220 gtgagttaat atatttggtt atatttattt tttaggagaa gttttgtatt ttttgaaagt 167280 gaaatgtttt taggtgggtg atattgatgg tgggatttgt ggttttatta gtgttttatg 167340 agagatgttg ttgtgtgttt tattaagttg tattttattg ttttttaaat gtggtttgta 167400 gatatggtgt tgagaatgat ttgggaggtt taaattataa tatggtttaa attaatagtt 167460 ttttgatgat ttggtattat tttaggatta aattgagatt atttgaggat gggtgtggtg 167520 gtttatgtgt gtaattttag tattttagga ggttgaggtg ggtggattaa ttgaggtttg 167580 tagtttgaga ttagtttggt taatatggtg aaattttatt tttattaaaa atataaaaag 167640 tagttgttgg atatggtggt gtatgtttgt agttttagtt atttgggagg ttgaggtggg 167700 agaattgttt gaatttagga gatggaggtt gtagtgagtt aagattatgt tattgtgttt 167760 tagtttgggt gatagagtaa gattttgttt tttggtaatt aaaaaaaaaa aaaaaaattg 167820 agattttttg agttgtattg tttagtatga tagttattgg ttgtatgggg ttatttgaat 167880 atttgaaatg tggtgatttt aagtggagag gtgttgtgtg tgtgaagtgt attttgggtt 167940 ttagagtttt agtaaggggg aaagaaaaga atattaaata tttgttattt ttatattgat 168000 tatatgttga attgataata ttttgggttt tgttaagtga atgatattaa aattaatatt 168060 atttgttttt atatttttta atgatttttt tttttttttt tttttttttt ttttttaaat 168120 atggggtttt atattgttgt ttaggttgga gtgtagtggt atgattttgg tttattgtaa 168180 tttttgtttt ttaggtttga gtgatttttt tgttttagtt ttttaagtag ttgggattat 168240 aggtggttgt tattatgttt ggttaatttt tgtattttta gtagagatag ggttttgtta 168300 tgttggttag gttggttttg aatttttgat tttaggtgat ttgtttattt tagtttttta 168360 aagtgttggt atgataggtg tgagttattg tgtttggttt gtttttatat tttttattgt 168420 aggtgttgga aaatgtaagg ttgtgtttgt ggtttatgtg ttgtttttgt tggagggttg 168480 gattgagggt tagttgagaa ggttttgggg ttgttttatt tgaatgttga gtgtgtgttg 168540 agtggtagag aattttgaga agtgttgaag gatagaggtt ttgtgtgggg gatgtagttt 168600 taggttggag atgttttttt tgtgttttgg agatttttat ttggtgatag taagaggaat 168660 tattgtaaga ggggtggtta ttttagtaaa gtatttagga tgttggtttt ttagtttagg 168720 aatttagagg tagaggaggg gaggaggttg ggtttggagg agagtagggt tttgggtttt 168780 gggaaaagtt tggggggtta gaaagttggg ggatagattg aggttagagg taaagagaag 168840 aaggtttgga gaggagggtt aaggaagaag ggttttgttt atggggaggg agaggtttat 168900 ggggtagggg tgtggtggga gttgtatttt tgaggttttt tgttgatttt gatatttggt 168960 tagaaaggag ttttttttgg tattttttgt tagtggtttt tggagttgtt ttttaggggt 169020 tagtgatgag ggtgttttgg gttgggttgt agatagtgga aaagataggt tttttttatt 169080 tttagtgttg gggaaattag ttttttggag gaagggggag ttgtattttt tgagtggttg 169140 tattttttgg tttagatgtg tgtgttttgt tgtaattttg gtgattggtg ttggtggtgt 169200 ttattttatg gatggggaag gttaaatttt atagatattg agtgataggt ttagggtttt 169260 ggattttagt gtttgattta gaatttaggt ttttgatttg ttattagttt tttttttatt 169320 tagatgggaa tagggatttt gggtatgtag ttttttttta gatatttttt tggttttggt 169380 ttggtgtttg gagattagta gtagtagttt tttatggttg tttattgtga gggtggggag 169440 ggttgtggga ttaggaggtt ttagggggaa agttggttat gaggagtggg aagtgatggg 169500 ttagatgtta gtgattgttg gttggggagt tgttggatgt ggttggtttg tttggttagt 169560 gtggtgggtg ttttggggtt ttagttattt ttagttatgt gtgggggtgt gggatgggaa 169620 aggtaagagt gtgtggagtt tagttagtat ttaatatgag gttttgtggg ggttgtttga 169680 gggtgtagtt tttagaattt agtttttggt ttttagaagg tgttattaaa ggtttttttt 169740 tatttgagtg aatttttttt agtttttagt aagtttttgg aatgagttta tttttaggtg 169800 ttttttttta gtgtgggagt ggttatgttt ttgttgggag tgatttattt gggtttagag 169860 gttgtggtat tgagatgggt ttggtagatt ttagtgttta ggtttagttt ttatagtgtt 169920 agtttttttt tttggggatt tttttgtttg tgtttttttg ggttttagta tattttaggt 169980 ttgtagggag ggggagagga agagattgat ttattggtta ggttttttag gggttggaga 170040 ggttggagag gtaggagttg gattagattt gaatttagag gtttttggag gaagagttta 170100 gggtgagttg tgtttttatt ttttgttttt ttttttttgt tttttttttt ttttatggtt 170160 ttagttagta agtatttggg gtagagggga taaatttagg tggttgtgtt ttagttttgg 170220 ttgtaggttt gaatggtttt ttggggtggt tggttatgtt ttttgagagt ttagttgtgg 170280 tgatgtttga gtaggtaggt gggggagtat ttaggaagta ggggtgttag gtagagtata 170340 aggagagagg gtgtttaggt tagttttagg atttggttga gaggaggggg ttttttatgg 170400 gtattgtttt tggtaagtat agggataagg gtaaggatgg tatggttaga ggtttttggg 170460 agtttttttt tttttttttt ttttagtagt ttttttttat tttttttagg gattttgtta 170520 ttttttttta gtgtgtggta gttttttggt gttttttttg tgtttttagg ttgtttttgt 170580 gttgggtttg ttgttgggtg tttttatttt tgtttgtttt ttttttttgt tttttttgtt 170640 ttgttttttt ggagtaattt tttattgagt tttttttttt aggtagttga ggtttttttt 170700 tatttttgtt ttgtgttttg ggaggttttt tgttttgtga ttataaagtt tttttgattt 170760 tttgtttggt tttgagttat gtgatttggt gggtgggttg tggtttttgg tgtgtttagt 170820 gtagtttgat gttttgttgt tggggtgagt tttgtttttt tgtttttttt agttttgtat 170880 tattggtttg ggggttttta ggtggtgtgg ttgtgaggtg gattttgatg gttatggtgg 170940 tggtgttggg agttatgttg tttttgggtt ttggtttgag gttggtagga ttgagtgggg 171000 tttttaggag aggggtggtg gggagtttga tttttatgtg gggattagat ttttggtttt 171060 aaaatagaag aatagggttt tgtgtggtta tagttatttt tttgtaaata tttggttaat 171120 taagttgagt ggttaagttt ttttgttgtt tggagttttt tggaatatgt tttttttttg 171180 taaggggttt ttttggtttt taggagggtt aggaagaaat ttgaattggt tattgttttt 171240 tttaaaatta ttttgtttaa gttattattt ttttgggttt ttgaagattg gttggttgga 171300 ggttggagat agttttaatg tttgaaatgt tgtaattgaa gttttttgtg gtgttggtat 171360 tgggatttag ggagttgttg ttatagtgta gttttggatt tttggatgtg ttggatatgt 171420 gtagggtgtt tttgggagga gtggggaggg agggtgttgt tggtggggtt ggtttgtgtg 171480 tgttttgttt ttttataatg gtatgttgtg tgttggttat gtagaggtat gttagtgagt 171540 aggggttgag ggattttttt aatggatttg tttttagagg gtttttttat gttgggagaa 171600 ttttagagat taaattatgt agttaatggg gtggtttttg gttttaaagt agggaggggt 171660 gaggagtttt gtaggtaatg ttatttgttt ttgaaatgtt gttttagtga ttttggggat 171720 tgatttagtt tttagtttgt tgtattttat ttttggtttt tttttttttg tttttttatg 171780 tgaaatttgt tgtgttttgg ttagaggttt ggggaatagt tttttgttta tttaagataa 171840 gtttgtaatt ttttttttgg agaaaaatat gttatttgga agtaggttga gtagtggttt 171900 tttggtaggt ttgtttgggg ttgtggagat agtatttgtt ggattaggat ggagttggaa 171960 tttggtttgg attttatatg agaaaatttg ttggaagagg aggaagtaga aaaaggtttt 172020 attttttaat aatgttgtgg gttttttttt tttatttatt gttattttgt tttgaaattt 172080 aatggggtta tgtgtgtttt tatgaatgtt attttttttg gttaattttt ttggtagttt 172140 taggagtttt tttttaggaa aaggaagaag gtgtttgttt agtatttagt atatgagttt 172200 ttgttggaaa ggtgggattt ttgttttttt ttgggttttt tttaggttga gatgtggtta 172260 aggaaggttt gtggtgtggt ttgttttttt taatgtttgt ttttggagat ttgagttgtt 172320 gttgattttt agtttgtttt ttttgttttt tggttatttt tgtgttgggg tggttgagat 172380 attattgtat tggttatttt gtgtttttat tagtttttgt ttttgtaggt tgttattgtg 172440 atggtgatgg ggttaattta gttgtggtgg ggaggattta ttgtgtgtgt ttggggggtg 172500 gtgtggggta ttttgggatg agaagatgtg atttttgttt tgagagtttt gttttaatgg 172560 aaggtggggg tatagttgta ggtagaagtt attaagtatt gtggttagat tagtatttta 172620 tgttaaaaat ggttttgttg gttgggtgta gtggtttatg tttgtaattt taatatttta 172680 ggaggttaag gtaggtagat tatttgaggt taagagtttg agattagttt ggttaatatg 172740 gtgaaatttt gtttttatta aaaatattgg ttaatttggg tatggtggtg tgtgtttgta 172800 atggtagtta tttgggaggt tgagatagga gaattatttg aatttgggag gtggaggttg 172860 tagtgagttg agattgtgtt attgtatttt agtttgggta ataagagtga aattttgttt 172920 taaaaaaaaa aaaaaaaagt tttatttggg tttgggattt gttttttgaa tattgggttt 172980 attgtgtttt ataaggattt ttattttgga agttttagat ttatttgggt aattagagtt 173040 tttgggttga ttatttttta gttttggtta gttttttggg ttattgtatt tttttaattt 173100 tttgttgtgt tatggttggt ttaagttgtt tttattagat aatgtgaggt atttttatag 173160 gaggggataa ttttgttttt aggagttttt tttttttgtt tttaggtttg gtgtagtgtg 173220 tggttttttt gttggtgtta aaggttttaa ggttttttta agaagtttgt tattattatt 173280 agtagttttt gttatttggt ttttttgtat atgtaagttt tttttatata ttttggatgt 173340 ttagggtttt tgtttttttt ttttggttgg gagtgtggga agagggtttt attttaatgt 173400 ttgagagtag ggttaatggt tagggtaagt tgtgggggtt tttttttgtt ggtttttttt 173460 tgtagttttt attttaatat agagtattga tattatttgg gttttgggaa gatttggagg 173520 ttgattattt tggaggtttt tagtgtttta tagttatttt ttggggaaga ggttttttga 173580 gggatttgtg gtttttggtt gggattttag ttttagagtt ttgttttttg gtgttgagtt 173640 ttgatttgtt tattgagtgt tagtttggtt tttggatagg tagggatttg tttttggagt 173700 ttagtagagt tttgggaagt ttttttagga gggtttttga gggtggtggt tatgtttagt 173760 ttgttgtatg tgtgagtttg tttgatgagg aattggttgg gaaggtgtgg gtttaattat 173820 aggtttatga gggttttttt tgtttttatt taggaagtag tggagatttt ggtatattta 173880 gtatttgggt ttgtgtttgt ttagttgttg gtggaattat gggagttttg ttttggggtt 173940 tgtagagtag tagtgggaat tttttttatt ttagtttttt ttagagttgg ttgtttaaat 174000 ttgttgttgt ttagtttttt tttttttttt tttattaatt ttgggaattg tatattgttt 174060 attttattgg gttttggagt gggtgtagga agagagagtt taatatttag aggtttgggt 174120 tttttgtagg tgtttgagtt gttgtggttt gagttgggtt ttttgttgga attattatag 174180 tagatttaat gatttgtttg taggagttgt tttattttag ttgattttgg ggttgtggga 174240 aggggttggg ttttggtttt gttgggggtg gggggttagt gtaaagggtt tgaaaagtgg 174300 tagaggtgat ggtttatttg tttttttttt ggttggttgg tttaaatgtg attggttttt 174360 tttttttttt tttttttttt tttttttttt tataaataat attaaatgtg atttgttaat 174420 gtatttattt gggtttagta gttggattat gggtagaagt attttagatt tgttattttt 174480 tttaagttaa gggtggggaa tattttttgt gagattttgg tttttgagtg tttaagattg 174540 tttttggaat tttaattttg ggttggtttt aggggattga tgttgatgga gttgttgata 174600 ttgatttttg gtttttgtat ggtttttagg aagggggttt tttgtttttt gttttgttga 174660 gtttggttgg tagtattttt tttttaggtt tgtgtttttg gtagggtttg ttgtttttgt 174720 tttgttttgt gggtgttagg ttttaagtat taggtgattt ggttattgaa tggttattga 174780 atagttattt ttgttggtgt ttttagtgga atgtgtatgg atgttttttt ttttttagat 174840 ttttgttttt tattttttag tttttgtttt aggggttatt ataggattag gaggtatgta 174900 gatgtgggtg gtatatttat tgggtagatt tagttttgaa tttgtatgtt ttttttaagg 174960 gggtttttag tgggtggggt tgatggtgtt gttttttttt ttgttattag aatggatatg 175020 aggattgtgt tttgttgatt tatgttttga gtttttagat gttataggtg tttgtttaat 175080 gagtgtttga atgaatggtt agtattgtgt gattgtagat ttttaatttt tatttaaata 175140 gtttgtggtt tttgtgaggt tattttgaga tagttttata agaattttta ttttttttgt 175200 atgttttgta taaggttttt ttggggggtt ttttagaaaa agggttaaag agtagtattt 175260 ttttggggat ttgaatatga ttttttttgg ggtaggggat tgttttggaa gatttttggt 175320 attgtttttt atgtgttatg tgattaggag ggttttgggg taggatggtg ttttttgtgt 175380 tttgtgtgtt ggggttggag gaaatattgt ttgtggttgg tgttatttgt tagttttgaa 175440 gattaatgat gggttggata gtggttttat tgagtgggag ggagaattgt tgttgtttgt 175500 agttgggggg ttgggtgggt gggagttgag gttagggaga atagtgtaga tttggtatgg 175560 agaggtttgg aggaggagta gggggtttta gttatttagg gtgtagggat gttatatgag 175620 gagtaggtgt ggtgtgtgtt tttttgtggg ttttttattt tttggttttg ttatttgtat 175680 taggttttgt ggtgagaggg tatagagtgg aggaaggtgt tgtggttagg gtaggttata 175740 tgttgtgtta atggattgtt gttatttgtt gtttttgtgg ttttgttgtt aggatttttt 175800 agtattaggt ttttattatt aggtatgggt tttataggta ttattggttt tttgaagtta 175860 gggatagatt ttatagataa tattgagttt ttgtagttag ggatgggttt ttatggttag 175920 tattagattt tagggattag tattgggtat ttatagttag ggataggttt ttatggttag 175980 tattaggttt tagggattag tattgggtat ttatagttag ggatgggttt ttatggttag 176040 tattagattt tagggattag tattgggtat ttatagttag ggatgggttt ttatggttag 176100 tattaggttt tagggattag tgttgggttt ttatagttaa ggataagttt ttatggttaa 176160 tattagattt tagtgattag tattagatgt ttatagttag agatgggttt ttatggttag 176220 tattaggttt tagggattag tgttgggatt ttggatgatt gaaggagggt atggttgatt 176280 aaagttgtag gagttagttt ggttattttg aggtattaag ttattattgt ggttttaggg 176340 gatttagatt tttttatttg tttttttgaa ttttggaatt agatatattt gggtttagtt 176400 tttgtttttg gggttgtgtg tttgggatgg ttgttttatt tttttgaagt ttagtgagat 176460 ggggatggtt gtatagggtt tggtatagat ggtatttgat ggtatagggt tatttgtttg 176520 tatttatata gttttggttt ttgttttggt tgtgtattga gagttttatg tttagatttt 176580 tgttgagttt ttaagttttt ggttatgttt taggtttttt gtgagaagta ttattgtatg 176640 gattatgttt tgggatttta ttttgggttg ggaagtttgt tttatttttt taagtttttt 176700 ttagaggtgt tttatgtttt attattttta ttgtttgagg ggttagatag gggaatttag 176760 tgtgggaggt ttagaggtgt tggagtagat gttaagtgag ttttgtgttt atgtgttggg 176820 ttttggtaga tattttgaat gagttttttt tttaggaagg agattggggt tttagtttaa 176880 gttgtggttt taaattttgt gattaagagt ggagaaaagg taagattttt ttttttagtt 176940 ttttagaata gttgatagtg gtggaaatat ggggtttata ttgaattttt ttgtaatttg 177000 ttgaagagaa tttagtttat atttttaggg gtggaggttt ggttgatttg gtagtgtgtt 177060 tgtttttttg gttatagttt attttggatt gggtattttg gtgttttttt ttagtgatgt 177120 agtgaagtta ttatgatgtg tttagttggt gagaaagtgt tttttgtaat gttttatttt 177180 ttttagaggg tgaataagtt ttgtttatta taaataatta tttatagaat atatgaggtt 177240 taatttaatt ttgggttatg gtagtgtttt ttgggtaaat ttatgtgtta ttttagttag 177300 agtttgtgtt tttataggtt ttttggattt attttgaagg ggggttggat tttttgtttg 177360 ttttgatgag agggttgtag gatagttttt agtgagtttt tttgagggtt gtaatttttt 177420 tttttggtat ttttttgttt gttaggaatg ttttaagttt ttagtagaag tttatttatt 177480 atagttgttt tttattttgt ttattatttt ttttgttttt atttatttag tagattttgt 177540 gtatagttta gtgtaggatt tagggtggga aggtgttttg ggtgggttgg agtaaggttt 177600 ttagttaggg tggggtttta aggtgggttt atagttagga ttgtgatttg ggaggttttt 177660 ttttgttttg ttttagtttt ggtattgttg ttgtttttgt gtttagtgga gatttattgg 177720 ttttaggttt taaaatttta gtgaggtttg tagataggga ggagttttat ttgagggtag 177780 agtgattgtt gggtttattt gtttgttatg aattatgtgg ttttagattt gttatttttt 177840 tttttttaga gttatggttt tttgtttgaa aaatggataa tgatggttat tatgttaggg 177900 attattttga ggataaatgg ggatgaaatt gaagaggttt agtatggaat ttggatatag 177960 aagtgttaat tgtgtgttat tagttgtggt ggttgttaag gtttaattat atggtagtta 178020 tgggttgagt ggtgggtggg aagtggggag taggagtatg taagatgggt atttttgaag 178080 tttttgattt agtgagataa gtatatattt agttttaaga tggagtgttt taggaaggtg 178140 gagattgtaa aggttttgtg gtgtaggagt gtgagttgta tttttgggtt ttttagaatt 178200 ttattagagt ttagggagga ggttagttta gatatagggg taatgggaga gatgggagtg 178260 agaaaatggt ttggtgtttg gaagtggagt ttggaaaggt gggtgtgggg atagaggagg 178320 gttttggggg ttatgggttt atgtgtttag gaggtggagg tagtgaatgg ggttatggtt 178380 ggttttatat gtggtattat tagttttgtt gagtttgtat ttgtttttta ggttttttga 178440 gtgttattat tatttggtat tttttggttt gatttttgtt ttttgtttgt ttgggaagag 178500 tgagattatt tgtttaaagt tttttagttg tttttaatta ttttggttgt tttttggttt 178560 tgtttagggt tagttgttga tttgaattgt ttggtgttat ttttttagat ttttggggtt 178620 ttgttttggt attaatagtt atttttattt ttattattta tttgtatatt tatttagtag 178680 tgttttttgg gtatttattt agtaatatta aggtgttgag atgtggttgt ggttaagatt 178740 tgggtttggt ttgtgaggat tttgtagttg ttattttttt agagtatagt tttagttagg 178800 tatattgtgg ggtttagaaa gagaaattaa tatattgtgt ttgtttattt tgagttgtta 178860 taaggaatag ttgaggttgg ggggttattt gatttatggt tttgtaggtt gtataagtgg 178920 tgttagtatt tgtttggttt ttggggaggt tttaggaagt ttttttttat ggtagaaggt 178980 gaagggggag ttggtatgtt atatggtgag agagagaatt tttagatttt tttttttttt 179040 gaaatggagt tttgttgtgt tagttaggtt ggagtgtagt ggtataattt ttggtttatt 179100 gtaattttag ttttttgagt agttgggatt ataggtgtat gttattgtgt ttggttaatt 179160 tttttgtatt tttattagag atggggtttt attatgttgg ttgggttggt tttaaatttt 179220 taattttgtg atttatttat tttggttttt taaagtgttg ggattatagg tgtgagttat 179280 tttatttagt ttttttagat tttatagtaa ttagattttt tggattttgt gattgtgggg 179340 agggtattaa attatttatg agggatttat ttttatgatt taagttttat tttttttagg 179400 ttttattttt aatattaggg attatatttt agtatgagat ttggagggga taatgtttaa 179460 attatattat atgtgatttt tttgtgtgtg tgttagtttt tatatttggt taagtagtag 179520 aagttttttt tttgtttttt gttgagagag tggtggggga gaaatgattt agggatggga 179580 ggttggtttt ttgaggggtt ttggtgtttg tggagtggga gtgtgggaag gtttttatgt 179640 tgtgtgtgtt gtgttgggtt ggttttttat agtttattgt ggtgtttttt gaggattgtt 179700 ggggaggaaa gagttaatta atttggggat ttagttgttg aagttattat taaatttgag 179760 tagtttaggg gttttttttt ttttgggttt tatgttattt agtatagtgg ggtttaattg 179820 aatttttttt tattttttaa ggtttttggt tggtgtggtt ggggtttggg atatggggag 179880 tgagagggtt tgggtttttt ttagatttgg agtgggttta ttagaaatgg tttaggaaat 179940 tgtgggggtt atttttagta gttgggggtt tttgtggtta tttttttttg gttttgttga 180000 gtagttttgg tttttggagt ttttagtaag ggatgtgggg gtttgttagg ttagggtttt 180060 tattgttgtt gttatgtata gttgtatttt gtatttgggg agtggggtgt tgagtggggt 180120 gtttgggagg taggtttttt tttgtttttt ttgtttagag attttgggga tgagttgagt 180180 gagatttttt tggtttttga ttggttgtgt ttttgttgtt attttttatt ttttttaagt 180240 ggaggtttat gatttttttt tttatttaaa agggttattt agtgatttag tagattttag 180300 tttgtgttat ttagggtttt tttaaaaatt tgtggggagg ttgggtttgg tggtttatat 180360 ttttaatttt agtattttgg gaggttgagg tgggtggatt atttgaagtt aggagtttga 180420 gattagtttg gttaatatgg agaaatttta tttttagtaa aaatataaaa aattggttgg 180480 gtgtggtggt atgtgtttgt aattttagtt atttgggagg ttgaggtagg agaattattt 180540 aaatttagga ggtggaggtt gtagtgagtt gagattatat tattgtattt tagtttggat 180600 gatagagtga gattttgttt taaaaaaata aaaataaata aataaaaata aaaatttatg 180660 gggggatttt tgtgtttatt ggttggtgtg aggagagggt gaggagttgt agagaaggta 180720 ttaggttgag gattgttttt atttttgggt tatagaattg aaggagggga tatatgaaag 180780 atgtttttag atttgggttg gaggttgggg atatttgagg gtaaggatga tgttgttttt 180840 gtttttgttt gtagaggagt gtatagggtt tattagtttt ttgttgttgt ttaagtgata 180900 gttttatgga gatagaattt atatattgtg atgttgattt ttttaaaatt tatagtttaa 180960 tggttttgtt gtatttataa agtgattgta ttagggttat ttagagaaat agaattaata 181020 gaaggtgtgt atgtgtgttt agataaagag atttattatt atgaggagtt ggtttatttt 181080 attatagagg ttggtaagtg ttaagattgg tagagtaaat tagtaggttg gagatatggg 181140 agagtttatg ttgtggtttt ggtgtttatt tgaaggttta agatttagga gagttaatgg 181200 tgttgtttta gttttgagat ttaggaaaag tgtatgtgtt agtttgagtt tgaagtagga 181260 aaaatttgat gttttaggtt gaaggtggtt aagtgggaag aatttttttt tatttaggtt 181320 ttgtgttttt ttatttagat ttttaggttt ttgttataaa attataaaga tttgattaga 181380 ataaaatttg agaaaaaatt tttttttttt attggttttg gatttattgg ttgggatttt 181440 ggaaattaga ttgatagaga ttaataggaa ataagtataa taatttaagt aagttttatt 181500 tgatattgag tttttataag gaaatgaaga tttagagaaa ttgttagttt gagtggtttt 181560 tgttttgttt tgagataaag ttttattttg ttgtatgttt aggttggaga gtagtggttt 181620 gattatggtt tattgtagtt ttgatttttt gggtttaagt tggggtttag ttgttggttt 181680 tgggagttgt tttgaattta tttttaagtt ttagtttaga tttttaagta gttgggatta 181740 taggtatgtg ttattttgtt tggttaattt tttatttttt gtagagatag ggttttatta 181800 tgttgtttgg gttggtttta aatttttggg tttgagtaat ttttttgttt tggtttttta 181860 aagtgttggg gttataggtg tgagttattg tgtttggttt aggtttgaat agtttttatt 181920 tgttttgttt gttttttaaa tttgtttgtt gtttgttttg agtagttttt ttgtttattt 181980 tttttgtttg ttttttgttt aggttggagt gtagtggtat gatttttgtt tattgtaatt 182040 tttgtttttt gggtttaagt tatttttatg ttttagtttt ttaagtagtt gtgattatag 182100 gtgtgtgtta ttatatttgg ttgatttttg tatttttagt agggatgggg ttttattatg 182160 ttggttaggt tgttttttaa tttttgattt taagtgattt ggttattttg gttttttaaa 182220 gtgttgggat tgtaggtgtg agttgttgtg tttagtttag gtttgagtgt ttttatgttg 182280 ggtttgatga agagtggaaa gttgtgggaa attgtgatag agtaataaaa gatgagttga 182340 atagtgagtt tgtgggggtt ttggtaagat ttgtgtattg gggttttttt tagatttttt 182400 gtttttggag atgaggttgt ttttttttgt tgggtgtagg gagggtattt tttatgtgag 182460 gggtttatga tttattttag agaaggggta ggttagtgag ttttttttgg atttgttatt 182520 ttttaaattt ttttagttga aaatatttat tatgttaagg tattgtattt tggagtgtgt 182580 gttttaagtt ttgttgtttt taattgattg ggtgaggttt atttttatta gagtatatag 182640 tttgttttat ttaggttttt gattgtattt tttttttgtt tgttttgaga atatttatta 182700 gtagtgtttg tggttgtagt gtttatttta agataaattt gttgggaagt attttgtttt 182760 tattattatt tttatattat tttagtatat tgattttgga aataaaagat attattttgt 182820 ttatagtatt ttatttttag tagtggtatt ttttttaaaa aaaaatggta atttttagtt 182880 gggtgtggtg gtttatgttt gtaattttag tatttgggaa agttgaggta ggttgattat 182940 ttgaggttag gagttggaga ttagtttggt taatatggtg aaattttatt tttattaaaa 183000 atataaaaat tagttaggtg tggtggtagg tatttgtaat tttagttatt tgggaggttg 183060 aggttggaga attgtttgaa tttgggaggt agaggttgta gtgagttgag attgtgttat 183120 tgtattttag tttggatgat agagtaagat tttattttaa aaaataaata aataaataaa 183180 atttaaaaaa aaatagtaat ttttgattgt tgaaaatgtt aaattttaga gaatatagta 183240 tttttataag tgatgttaat attgtttttg attagttgtt ggttgaagat ttatttgatg 183300 aatttgattt ttttagaata gatgatttag atgattttgt tgttttgttt agaaataatt 183360 gtaggaataa tttaaaaaat tttttttttt tttaattttt ttgttttttg agatggattt 183420 tttttgttgt ttaggttgga gtgtagtggt atgattttgg tttattgtaa tttttgtttt 183480 ttgggtttaa gtgatttttt agttttagtt ttttgagttt agttgggatt ataaggtgtt 183540 tgttattata tgtggttaat tttttgtatt tttagtagag atggtgtttt attaggttga 183600 ttaggttagt tttgaatttt tgattttaaa taattggttt atgttggttt tttaaagtgt 183660 tgggattata ggtgtgagtt attatgtttg gttagttttt atatttaatt tttatataga 183720 gtatttagtt agatttgttt tagttttaaa gagtgtgttt atgtaaaatt aagtgagtgt 183780 tggtagtgag ttgaattttt taaaaggtaa aagggttaaa tattaaattt atttaaaaat 183840 atttttatag atatatttag aataatgttt gattggttat ttaggtgttt tatagtttag 183900 tttagttgat atagaaattt tttttttttt ttttgagatg gagttttgtt ttgttgttta 183960 ggttggagtg tagtggtgtg attttggttt attgtaagtt ttgtttttta ggtttatgtt 184020 atttttttgt tttagttttt tgagtagttg ggattatagg tgtttattat tatatttggt 184080 taattttttt ttttgtattt ttagtagaga tggggtttta ttgtggtttt aattttttga 184140 ttttgtgatt tatttgtttt agttttttaa agtgttggga ttataggtat gagttattgt 184200 gtttggttga tataggaaat taattattat agttatatag ttattgttat taattttagt 184260 atattttatt atttttaaaa gagattttgt ttttattagt taatttttat ttttaatttt 184320 gggtttttag tttttagtta ttgtttattt gtttttgttt ttatgaattt atttgtttta 184380 gatagtttgt ataagtggaa ttgtatagta tgtggttttg gtgtttggtt ttttttattt 184440 ggtagaatat ttttaaggtt tatttatatt gtagtaggtg ttggtgtttt attttttttt 184500 atggttgaat aatattttat tgtggataga ttatattgtg tattttttta tttgttgatg 184560 gatatttggg ttgtttttgt tttttggtat aattttgttg tgaagaattt tgtagtgagt 184620 gttggtttat aggtttttgt gtgaatatgt ttttattttt tttgggtaat tgtaagatta 184680 tgtggtttag ttaattagtt tttaagttat gtgtttgttg agggatttag gtttggtggg 184740 ggtgtattgt tgtgtttggt tagttaggtg ttgtgagttt gtgttgtagt tatttttttg 184800 tgttgtgttt tgaggttgtt ttgttggtat tgggtattgt gagttttagg aggttaaagt 184860 tttttttgtt ttattttgag tttaggtttt gttttatgaa ttaggatgaa tggatattga 184920 attaatgtag ggatgggtgg ggttggggtg gggatgtaga gtgattttgg gggtttgtag 184980 ttgggttttg gttgttgatt tttagttttt tttgtttgtt ggagtttaga ataagttaga 185040 aaggggaaat gtaaagtttg agtgtttttt ttgtggtaga ttggtaggtt tgggtgggtg 185100 agttatttgt agttagttgt agtgtgagag aggaagtggg aggggaggga gagggtgagt 185160 ttggtgtaat ttatttttgg aaggaggttg ggttgaggtt gggggaagtg atttttattt 185220 ttttgagagg attttttttt ggggttaatt ttaaattaag ggagataaga tttttttggg 185280 ggaggttgga agtgttgggg tttttaggtg ggtaggtttt ttagggttaa tgttttgggg 185340 aagttataag ttattatgtt tttggattgt tatatatata tatatatata tatatatata 185400 tatatatata tatatatata tatgagtaaa ttgtaatata aatgtgtgtt tatgaaagtg 185460 tttattttaa attattatat agtttgtaaa gtgaaggttt tggtttgtat ttgggtattt 185520 attgtttagt tagttggtag gtagtttgta ttgtagtttg ttattatttt ttagagatgt 185580 agttgaggag tttagttggt ttggagggtt tagtgggtgt agttttagga aagtggttag 185640 gtttgggtta ggtttttttt tttttttagt tttgggagaa attattatat gaatgtagtt 185700 tttttttgga gtttgggttg gaagggtttg ggaggggata ggtttttatt ttaggagttt 185760 ttaggttttg gttgttgttt gtgttagttg tgtgagtgtg agtgagttag gggttattat 185820 tgggtggaag gaagaagtgg gtattttttt taggaggtta ttgttggagt tttatagtag 185880 gttaatttta ggttttgggt ttttgggagg aggagaaaga agagaagtag gaggtgtgga 185940 gggtaggtta ggattagaag gtatataggg ttggggtagt gtgggagatt ttgggggttt 186000 ttttatttaa ttagttaata ttatagtgtt tataagaata tgttattatt gtagttttat 186060 tattttgttt tgattttaga aggtataatt gatgatttta gggaatggag aatttgagga 186120 aggttttgta ggagagggtt agatgtgatt gagtaaatgt gagttgtttg taaattgtag 186180 agtgtatgta tagtattggt tagttttggg gttagtgttt ttttggtgtt tagtttggtt 186240 tttgtatttt ttagtgtttg gttgggtttt gtgggggtta gggttgggtt tggtatatta 186300 gaggattttt attaagtttt tggtagtgtt ttagttatta aatttagttt gttagttatt 186360 aaatttgttt tgttggtttt tgaattattt ttttgttggg gttggttatg ttatgttagg 186420 ttttttatgt aggatggtag atggatagat gttgggatta agttattttt gggttgtgag 186480 atgtttgatt ttttgttggt gttttagaag atgttagttt tttgtggtat gttttttatg 186540 tggtgtttgg ggattagtgg tttttaaggg gtttttttgt tttagtgtgg ggagtggttt 186600 ggttaaggtt ttagtgtttg gttggagtta ggtataggtt taggtgtatt ggttggaggt 186660 tttttgttta tgggttttgt ttgttttgtg tttttggttt ttattgtgtt ttttgtgttt 186720 ttgggagaga ttttaggggt tttgagttta gtattggggt tggggagtgg gtggggaaga 186780 gggtggggat tagggttttt ggttgtagaa tagttaggtt ttaagttttt attttatttt 186840 ttttttattg ggtgttttat tttatattga ttattttttg aagaaaattt tttgaattgg 186900 ttttttattt tggttgtttt aggaagttta tttatttttt tgttttaatg ttttgtggtt 186960 ttagaaggat ggtggaagtt ggaaattatg agttttattt ataggtggtt atatattgaa 187020 gttgtggaga tgttgtggga aaggattttg gttagtgtgg ttggtataga gggagtggtg 187080 ttattggggt agatgggaat tgtggttgtt tttatgttgg tttgggagag atgaggggtt 187140 ggatgaaagg atagtagatt ggttatttat ttatttattt atttatttat ttatagtgtt 187200 ttattgggtg ttttggatgt gtaaggtttt gtgggtagtg aatgtgatag attttagata 187260 gtaattggag ggttatgtgt gtaagaattg agggatttag gttgggtgtg gtgttttaag 187320 tttgtaattt tagtattttg ggaggtagag gtgggtggat tatgaggtta ggagattgag 187380 attattttgg ttaatatggt gaaattttgt ttttattaaa aatataaaaa attagttggg 187440 tgtggtggtg ggtgtttgta attttagtta tttaggaggt tgaggtagga gaatggtgtg 187500 aatttgggag gtagagtttg tagtgagttt agatagtgtt attgtatttt agtttgggtg 187560 atagagtgag attttatttt aaaaaaaata aaataaaata aaataaaata aaaattgagg 187620 aatttagtgt agatgagtta ttttgggaaa ataagtggga gttttaggaa tagtatgggg 187680 aagggatggt tttggtaggg aggatttttg tgggtagttt tgttggaaga gttgaaaggt 187740 agttagagag gttgtgtgtg gatggaagtt gaagagtagg ttaggggtgt gtgttttgtt 187800 aataaagatt ttaagtattt attgattagg tataatatta tgtgttttat aaataaatat 187860 tttatttgat ttttagtatt tttatgagat agatgttatt attttatttt atatgtaaga 187920 atattgaggt atagagtggt taagttattt gtttagggtt atatagtatg ttggtggtag 187980 gtaggatttt ggagttatag gaatttggta tattttaggt gtaatggaaa ttagttatgg 188040 ttttatagag ggaaattatt agattagtaa attttatata tgttttttgg tgttttgagg 188100 aggagggatt tggatagggg tagttaatgg tggtggttgt gagatgtgtt gggttaatat 188160 tgatgagagt ttgggatgga tgagtggatt tggagtaatg gaaatggagg gtttaggttt 188220 ggtttttgga gatttagttg taatagttgt tggttggaga ggttgtttat ttagatgggg 188280 gatggggtgg gaggtaggtg agatgagagt tttagagttt agtttggggt atggttattg 188340 ggtttaagat gtttttagat gttggggttt gatagtgata gtggttgtag atatttagga 188400 tttagtagag ggtttggtat agtggggttt agggatatgt ttgtgagtta ggttggtatt 188460 taagtgtgaa tttggataaa gaaggtggta ttgttggtat tgaatgttta ggggttgggt 188520 gaagttagtt agggagaggg gtttttaagg tattaggatt gattttgtgg gtgagggtgg 188580 aggaggagat ggtagaggtt gagagaatag ttagagatag gaggaaggtt agtagagtta 188640 tgtatagaag tttggagaag atttgaggaa aggaagggtt gggtggttgt tattttttgt 188700 agttaggagg taagggtgat ttttgtgtgt tttatttttt agaggattgg tggttttatt 188760 tggttagaat tttaagttta gagatgtatt tgagttttat gttatggtgt aggtagtagg 188820 agttatggag taggtttgtg gggttatggt ttgtttgttg ttttttggtg tttttatttt 188880 gagtttaggg gttgtttgga tgttttgtgt tgtatttttt taggtggtgt tttagagagg 188940 atgaaagtgg ttattttaag gtgtgattag gtagtggttt atgtatattg tttttttttg 189000 gggagagttt gggatggaag ggtatgtgtg tgtttttgag attttttgaa taggttttat 189060 gtatttattt atttatttta ttatttattt atttatttat ttatttattt atttatgtat 189120 ttatttattt atttatttat ttatttattt gttaatttat ttatttattt atttatttat 189180 ttatttattt atttatttat agttatttat ttatttattt atttatttat ttatttattt 189240 atttatttat ttatttattt gtttatttat ttatttattt atttatttat ttatttattt 189300 atttatttat ttatgtattt atttatttat ttatttattt atttatttat ttatttattt 189360 atttatttat ttatttattt atttatttat ttatttattt atttatttat ttatttattt 189420 atttatttat ttatttgttt atttatttat ttatttattt atttatttat ttatttattt 189480 atttatttaa ttatttattt atttatttat ttatttatta tttgtttatt tatttattta 189540 tttatttatg tatttattta tttatttatt tatttattta tttgtttatt tatttattta 189600 tttatttatt tatttattta tttatttatt tatttattta tttatttttt tatttattta 189660 tttatttatt tatttattta tttatttatt tatttattta tttgtttatt tatttattta 189720 tgtatttatt tatttattta tttatttatt tatttattta tttatttatt tgtttattta 189780 tttatttatt tatttattta tttatttatt tatttattta tttatttatt tatttattta 189840 tttatttatt tatttattaa tttatttatt tatttattta tttatttatt tatttattta 189900 gttatttatt tatttgttta tttatttgtt aatttattta tttatttgtt tgtttattta 189960 tttatttatt tatttattta tttgtttatt tatttattta tttatttatt tatttatata 190020 tttatatatt tatttattta tttaattatt tatttttatt tttattttag aaagtatttg 190080 aagttgttgg ggtgtgtatt tggaaaatgt gttataagtt tttataggtt tttttttggt 190140 ttttttattt ttttgattgg tttttttttt ggatatgtag gattttgagt agtttttttg 190200 ggaggtgggt gtagtttagg taggttgttt gtaaagttag gattgaggga gttatattta 190260 aggtattgtg ggtttttaag gtgatggtat tgtgggttta ttgtttttag atttttttaa 190320 tttttaggtt tttgagtagg aggatttttg gggtagggtt tggagatggg aagagaaaat 190380 aattttagtt ttttaatttt tgttagttta ggtgggtgtt gtatggattg ggggtatttg 190440 gaatagttgg tttttttatt tttttttttt atttttttag tttttttggt tataattaga 190500 tagttgtgtg tgatgttttt tttttttttg aaggggttat ttagttaggt ttttatttat 190560 ggtttaggaa tgtgtttttt tttgtttgtt ttttattttt aagtaggttg tgtttttagt 190620 tttttgttgt ttttgaaggg tttgggtatg gggtagtttt tgtagtattt ttagggtttg 190680 agttgatttg tatagtagaa gggaattggg ggaaagtttt ttttttattt agtatttggt 190740 agggggttat tttgttgtat tttagagatt tttgtttaag ttttgttatt ttagatgatt 190800 ttataagttg ggggaggtgg agttttagtt tttatagttt ttgttgttgt tttattgttg 190860 agttttgttg tgtatttgtt gataggtttg ttgatagtag aaggggttgg agagagggaa 190920 gttttgggtt ttgttttttt taatttttgt ttaggggata tttttgataa gaggaaattt 190980 tagtttgtga tagatggtta gtgtttattt atttatgggg gaattttttt ttttttttgt 191040 aagtttgtag atttgttagg aattaaagga atttttggtt gataggttat tgtggatatg 191100 gttggagggt tggtatgggt tggattttgg ggttgttttg aggtaggggt tgtttttgtt 191160 ggaaggtttt ttggggtggg gaaggtatta gggttatttt ttgatttttt ttttgtagtg 191220 gatttatttt agagtttgag ataaggtaag ggggtagtag aaaatagaat ataaaatagt 191280 tttttttatt atatattgta ttagaagtta gaggatttat ttttggtttg ttttttttgt 191340 agtttaagtt ttgagagtgg ttttttagga agtgaatggt gatggtttgt aggttagagt 191400 ttgttttggt ttaagattga tgttttaata ggttgtggag tttgggtgaa aaaatttagg 191460 ttagggaggt ggtgggttgt aaatgaaaga atagaggagg gtttttttta gaaagtggtg 191520 ggtggtgtga ggagtttttg gattttgttt aaatttgatt ttattgattg gggttaattg 191580 aaattgtgtt ggtagaaagg taaaattgtt tgagattttt ttttttataa tagaggagag 191640 gtttgtttga aagggtttgg tgagggaaaa gttggaggaa ttttggttgg tagtaaaagt 191700 ggggattttt gttttttgtt ttgggggtgt tttggttttt gaatgaatga aagaggaggt 191760 tggatggaga tagatttata ttatttgttt tttttaggtt ttgtaaagga gtatataggg 191820 tttttgttgg tttttttatt ttgttagtta ttaagaagga gaaaatatta ataggggaat 191880 tgtaaagttg tagttttgtt taagttttat agtggaaatt ggaaagagtt ttagtttgga 191940 gaaaaatgta gttttttgtt tttgtaaatt tgtgtttttt tttgggaggt tagagttatt 192000 gtgtttgatt tttaagtagg gttttagagt gttttaggag gggaaggtag agttttagat 192060 ttttggtatt ttaggtttta attaggtttt gaggagatgt tttttgtttt atataaagtg 192120 tgaagtgtaa tttgatttgg agttagttaa taaattagat gagttgtgtg tattttaaaa 192180 atttagtttt tgatttttta tttatatata tttgtataat ttggttattt atatttagtg 192240 tttttatttt tagaagagaa taggaagttt ttagtgatat ttatggagtg tttgtagtag 192300 tttgggtagg ttagtaggaa tataatgtag tgaaaagtag agttgagatg ggaaaatatt 192360 ttgtttttag agttttttag ggatgatatt ttttattgtt tttgtttatt tgttttggag 192420 tttattttgt aaatagtaat ttgtttttat ttgagagttt ttttttgttg gagtttaggg 192480 atggagagta gttggtttta gttttttttt tttatttttt tgttttttag atttattttt 192540 tattttgaat aattgttttt aatttgtttt tttttttttt tagttgtaga atttagaatt 192600 ttgtgtgtgt ggttaaaagt ttagagagtg ttgtaggtaa tgttgagata attttattaa 192660 attttgtaag tttttattat attaagtttg tttgtttttt ttaattttta ttttatttta 192720 ttttatttta tagggatggg gttttgttat gttgtttagg ttggttttga atttttgggt 192780 ttaaatgatt tttttgtttt ggttttttag agtgttaagt tattttttta attgggattt 192840 atgggtttag ggattttttg atgaattgtt taaaatatgt gtgtgtttgt ttgtttgttt 192900 ttaatgtata tttttttagg gagagttttt attttttatt agaggtttgt ggtatatata 192960 tgttttgtat tattgtatta gattgtgaat tttttatatg ttaaagattg ttttaaattt 193020 gtttggaagt tttggttaat aaatatttaa ataaatgaat tttaaatttt tatgtgttat 193080 tattgttttt attttgatta tttttaagtt tgtagtgtta tttttttgtt attgtgaagt 193140 agatatttaa taaatatttg ttaaatgaat taatgttatg gttttggttt attaggattt 193200 taggattatt gtttattatt attgtttata gtttttttat tattttgttt tagagtagtt 193260 ttttttttga ggtttgttta tttttgtatg tgtgtttagt ttttagtttt gttgttttat 193320 tatttttttt tttttatttg tattttttga attgttaata gttaataata gttttttttt 193380 ttatttattt atttatattt gaagtgagaa gttattattg aggtttttgt ggattttgtt 193440 agtttaattt ggggtggttt tttggaggtg gagtttttag atgagggatg gatattttgg 193500 tgtttgttgg gtagatttat ttgggagttt tggtaggggt tttagggtag ttttgttttt 193560 ttattttggt tgtgggattt ttggtgtatt agggtttttt aagtaagtat ttgtgttttg 193620 ggagagttat aggtaggttt gagagggttt ttggaatttg ggatttttag tttggtttag 193680 tagttggtat tattattttt tttgtaaggg aagttatgga aattaagatg ttaatgtgtt 193740 ttgataggtt tggggtggtt ttaagttttg ggaagagttt tggtaatttt ttttggttgg 193800 tgggtagaat ttttttttgg tagtttaggg ttttgttttt agttttttgg gggagagtaa 193860 ttgagggagg agttggaggt taaggtttta gtgttgagtt gtttgtattg tagttgtatt 193920 ttttgggttt tggttgtagg aattttatat ttttttagtt tttttatggt ttttgaagat 193980 ttggtttggg gagggggtta gtagtttggg gtttatttat ttggttttaa attttggttt 194040 tattgtttat ttgttttgtg atttttataa ttgataaaag tttttttggt tttggttttt 194100 ttatttgtga aatgggataa taatagtggt tattttatag gattgtgtga tgatttatta 194160 gttataatag tttttgagta gtgtttagag taatatttgg ggtttggtgt agtggtttat 194220 gtttataatt ttagtatttt gggaggttaa ggtgggagga ttgtttgagg ttaggagttt 194280 gaaattagtt tgattaatat tagtgagatt tattttttaa aaaaaaaaat tagagtaatg 194340 tttggtatag agagttttta gtaaattttg gttgttgtga tgagttttgt ttttttattt 194400 gtttatttat ttattagatt ttttgttggg gtttgttgtg agttttatgt tgttttgaag 194460 aaagttgggt tggggtgagt gtgatggatg aggtgtttgg ttttataaat tttgtgtggg 194520 ggggttgtgg tgagaggaaa ttgtatatat tattatttag ttattattgt ggggagattg 194580 tttggatgta gagagtaggt tttgtgtggg agtggggagg gtaagttttg gttgtgaggt 194640 agggtttttt taggatttag tagggatttg aaggattttg taggtattta gggagatagg 194700 agaggaggag ggagtagttt tggttggata ttgttttttt agtattgttt gtattaggga 194760 tttatttagt tttaagaagt ttttttgtgg gggataggga gtatttgtta gtttatagga 194820 tttgaagtgt ttttatgggt ttaagttttt gggaaggttt gtaggtggtt gtagggttgt 194880 tgtaggggtg ttggttttag ggtttggatt taggggagtt tgtagaggga gggtagttgg 194940 aggttgtttt agtgtgtatt gttatgaggt aaagtaagga gattgttggg tttatgttgg 195000 gttggggtgg atggaggtaa ggaagttttt gttggggtaa gggtattagt tgtagatgtt 195060 ggtagttttt ttttggatat gggtttggaa ggttgatagg gtgtggtgag tgttattggt 195120 ttttttgttg tggtttggtt agtggtttta taggtttttg tgggtaggag gaggatgatt 195180 ttgtattttg tttggttatt attggtagtg atagataagg tgtgtgggga tgtggttatt 195240 ttggtttgtg ttttgagagt taggtgtggg ttgggtttgg ggaagatagg ggaatggtat 195300 tgatttgatt ttgagtattt tgttttgggg tgtaggtttg gttgttattt ttttggagtt 195360 gggaatggta ttgggtggtg gtttagggtt ttttgtttta gtggtattat ttttgtattt 195420 ggttagtaag gttgatggga tttgtgtgga tatttttggg atgtagatta ggtagtatga 195480 tatataggga ggggtaggta gagaagggtg gtttttgggt tttggttttt aagttaggtt 195540 ttgtaagttt gttgtgttaa gttttttttt ggtattaggt taggtgggtt agggttagtt 195600 ttggggttgt gatgagtgtg agtgttttta aagtgtgtta tgtttaatag ttgttttttt 195660 tttgggtatt gttttttagt tagatatttt atagtttttg ttttagttat agatagtaat 195720 ttgatttttt tatttttggt aggttttggg gttggggtaa gaatttgtta ttaagtgtag 195780 atgtttttag agggtgttgg tttagggttg tgtggattat agttttttta tttttgtttt 195840 agatttattt gtaattttgg agaaaagatg gtttagtgga tgtttgtggg gaggagggag 195900 ttggttttta ggatgagtag atttgggggt agtttttatt atgggattgg tgatttattg 195960 ttattagtgt tagtgaatgg tagaggggtt ttggtataag gtttgggttt agaatgggaa 196020 tttgtagaga aattgttaag gttttttgtt atttgatatt tttgtttggt tgttatttta 196080 gaaatatttt tgttgtaaga agatggggga gtttgtttgg ggtatggttt ggtgatatta 196140 atttgagaat tttaggttta agtgttggtt tttgggtttt agttgttttt tgagttgtaa 196200 agttggtttt tgggtatttg tggaaaatat tggatttttt attttatttt attttatatt 196260 ttgggatata tgtgtagaat gtgtaggttt gttatatagg aatataagtg ttatagtggt 196320 ttgttgtatt tattggattt tttaatttag ttttattaga aatgattgtt tttttttttt 196380 ttttttgttt tttttttttt tttttttttt tttttttttt tttttgtttt tttttttttt 196440 tttttttttt tttttttttt tttttttttg tttttatggg gatataattt ttatattata 196500 ttatttgttg atttagaaag tatagttgag tggtattttt ttataatttt ttataagtat 196560 tatttttaat tttagaatgt tttttttatt ttaaaaggaa atgttatttt tggtatatag 196620 ttattttttt ttttttagtt tttggaaatt attaatttgt gttttgtttt tatagatgta 196680 tttattttga atatatgatt agaattttaa aagatgtgat tttttgtgtt tggttttttg 196740 tagttggaat gtttttagag tttatttgtg ttggtgtatg tttgtgtttt tttatggttg 196800 agaaatagtt tgttgtgttg atttagtatg ttgggttttt ttatgtattt gttggtggat 196860 gtgttagtta tttttggagt tgggtgtgtt gtgttattta tgggttgtat taggagttgg 196920 ggatattatt gagtaagtta tagttttggg tatttaggag tttgtagagt aggagttggg 196980 agggaggtta ggaggtgtat ggtttgtttg ttaggttgga gagatttgta aaaagttatt 197040 ttgagttaga aattagagtt tgaggttttt gatttttagt tgtggagttg ggagggaagt 197100 tttgtatttt gttttgattg tggggtgatg tgttagttat tgtttaaatt agaatttttt 197160 tgagagttga tgtgggtatt gttgataatt agtttggata tttgaaagaa tggaaagtag 197220 ggatttagat agatttttgt ataattgtgt ttgtagtagg gtgaggtttg gaggtgtgat 197280 ggggatttta atggggtagt tgttgttttg ttggagttta tggtttttgg ggggggttat 197340 aggtgttaat tgtatattat ataagtagga gtgtgaaatt ttagggttgt taaatttagt 197400 gagggttttg tgttggtttg gttatttata gtggtatttt aggaaaaaaa attattttat 197460 ggattttagt ttttttatta gtaaagagta ggttggattg gaattttgta ttatttagta 197520 tagttgttat ttatgaaatg tggttattta aatttaaata aaaatagaaa ttttgttttt 197580 tagttggatt agtttagtgt taagtgttta gaagttattt gtgaatatat tgtggtaatt 197640 ttttaaaaaa tgaaaattag aattattgta gtattttata attttatttt tgggtgtgga 197700 tttaaaagaa tgtatagtat tttaaagagt tagagatatt tgtatattta tatttatagt 197760 ggttttgttt atagtagtta gtgggtagaa ataatttgaa tgtttgtggt taaatgaatg 197820 gagaaattaa aggtgggata ggttgggtgt ggtggtttat gtttgtaatt ttagtatttt 197880 gggaggttga ggtgggtgga ttatttgagg ttataagttt aagattagtt tgattagtat 197940 ggagaaattt tgtttttatt aaaataaaat tagttgggta tggtggtggg tgtttgtaat 198000 tttagttatt tgagaggttg aggtaggaga attgtttgaa tttggggagg tagaggtttt 198060 ggtgagttga gattgtgtta ttgtatttta gtttgggtaa taagagtaaa attttgttta 198120 aaaaaaaaaa aaaaaagggt ggaatatata aggaatttga tttagttgta aagaggaagt 198180 taggatattt gtaatagtaa gggtgaattt tttgggtatt atgttaagtg aaataatttg 198240 gttataaaag gataattttg taggatttta tttatattag gtttgtagag tagttagatt 198300 tagaaaaata gtagaatgga ggttgttaga ggtttggggg atggggttgg ggagttgttt 198360 aatgaggata gtttgtttta taagatgaaa aagttttgga gatttgttat ataataatgt 198420 gaatgtattt aatattattg gattgtatat tttaaaatag tgattgtggt aaatgttatg 198480 ataattaaaa ggaaaagtta tgtggttagt ggttattatg ttgagtagtg taggttttgg 198540 atggtgttgt ggttatagat aatggagtgg gtgattttta ttattgtttt tagttgtttg 198600 agtattatgg tgttttgggg ttaggatgaa agtgtttttg ggtatggggg tttttgtttt 198660 ttttatttgg gagttttgaa ggtagatttt aaagtttatt tggttaggta ggagagtgag 198720 gtgggttttt gtattgtttt ttgtgtgtgt gtttgtttgt gggttagttg gggtttgtaa 198780 ggttgttttt tgagggaggg gttgtaggaa tggtttttat ttgtgtagaa ggtaagttat 198840 tgttttatgt taatggtaaa gatggggttt ggttgtgttg tattattatt ttttaagtgg 198900 ggtttttggt gggtaggatg tttggtttga tttgagtttt tgtagtgagt gttggtgttt 198960 gtggagggat ttagttgtag ttgagttggt tttttttttg ttttgggttt taggggtgtt 199020 gggggtgaga aaggagagtt tagggggtag tgtttttttt taggttttgt tggggagggt 199080 tgagggatgt tggggggagg tgggggtggg taggggttgg ttttagtttt aggtaaaatg 199140 gtttttagat ttataggtag atggaagtga tttttggtta tgtgggtggg gattgaattg 199200 ttgttttgta aggtaaggtt ttatgtttgg ttttaggaag tggttttaaa gttatatggt 199260 ttatggttag atgtagggtt gtgtttttgt ttatttaaag gttttggaag tttaggggag 199320 agtatttttg aagggggagt aggagtagga gtaaagtttt gaaggttttt aggttgtgtg 199380 gtttgggtgg gggttatgtg ggggtataga gagaggagtt ttggttttta ggtttgtttg 199440 tgggtattgt ttttagtagt ggagatgtgt ggattttttt ttggtatttt ttaataagga 199500 attatattgt ttttttgttt ttttaatttt ataagatagg aatttttgtg ttttgtggag 199560 gttgagaaga tggggaggtg tttgtgagga taaattagtt tttagttttt ggtttttaga 199620 gttttttttt tttttatttt tgatgtttta ggtttgggga gttttttttt gatatttttt 199680 gattgtttta gtgaaatagg ttgagaggga tggtttgaat tggttgggga tgtaggttgt 199740 agttaggggg tttagtgggt attttttgag tttggttttt gttttgtaag tggaagggta 199800 gttgaattga agttttttat tgtttttttt ggtttggaag tttgtttttt attttttggg 199860 tagagtgagg agtgggtgtg ggttgggagg gttgtttttt gtttgggagg gttgtttatt 199920 tgtttgttat gggggatgag ttttttgtag ttttttgtgt tgtggttttg gtttttatgt 199980 tggttttatt tttttgtggt tgtttttgtt gggtgtttat tggttttagg gaaaagttat 200040 tttttttttg gaggattggt gggaggggtt ttgtttggga gtgtgttgtg tggtttttgt 200100 tttagtgtag gatgtttgag gttagatttt ttttgggagg taggatgggg taaaagtttt 200160 tttgtaggta gagtagggtt tggatgggtt taagtaggga tgggggtata gaatagtagt 200220 tgtttagttt gtgtgggagt tgagggttat taagggtagt tttagtttgt ggggattagt 200280 agaggtatta tttttgtgat tagtgagttg tttgtatttg tatgtgtatg tattagtgag 200340 tgtggtgagt ttgaggtgtg ttgggatttg gtttgtgtat tagttagttt tgatgggaat 200400 tagttttatt ttgggtattt ttggaatttt attgtgtggg agtatttggg tttttagtag 200460 gtgttttttg ggtgtttgtt tttagtttta ggtttttgat ttgtgtgtgg tgttttaata 200520 gtagttagga gtagggttat tgaagggatt tatagataga agaggtttta gtgattttgg 200580 gaagtttagt tttatgtgtt ttatatattt aagagtaaaa tttggttttg gtttgtgggt 200640 gtgtagtttg tgggtgttgg ttaggtatat aagatggttg tttgggttag tttaggggga 200700 ggtagatgtg gtgtaggggt tttttttttt tatgagttta ggaatagttt tgtatttagg 200760 tatttgtttt gtatttagta tttttttttt ttttaggatt gttggtttgt tttatgggat 200820 tgaatatata attttatggg gattgatgtt ggttttattt ttttttttta taagattatt 200880 tatggggatg tgggaggtgg ggatatatgt tggttttatt tttgtttttt ataagattat 200940 tttttttgtg ttttggtttg tggattggtt tttaaggttt ttgagtggta gtaggtggta 201000 tagtttattt gagtagaggt gaaggagagg gttaggttta tttgggtggt ttgaggtagt 201060 gtggagggtt aggagaggag agtatttttt atttttgttt gagtagtttt ttagggtatg 201120 gagataggag tttagggtta gttttgtttt ggagtgtagg gggtttttag tttggtatag 201180 tttttagaag aggagatgaa aaagtttggt tttgggagtt tggggatgga gttttgttgg 201240 ggaggtagtg tggttgtagg atggtagttt tttagaggat attatggtta gggatattta 201300 tttgggggaa tttttagggg ttgtttgggt aagttgttta gtttttttga gttttagtgt 201360 tttagttttt ttatttaagg atgggtgtga taattatttg gtaggtgttt gtgtgtgagt 201420 ttttgttttg ttttaatttt tttgttgttt tttttttagt tattgaggtg gtttttagtt 201480 gtgttggtga tatggttgat atttttagag atgttgggtt taagtaggtg tttgtattat 201540 ggaatgagaa ggttttggtg gattttggtt atgtggggat tgattttatt ttggagtaga 201600 tgtgttggaa ggttatgaag tagggttttg agtttaatat tatggtggtt ggtgagtttt 201660 tattttgtat gttatttaat taatgttgga aattagtttt agtttttagg gtggtttata 201720 agtttttggg tttggttttt ttttttgtaa aatggggtag taattttgat tttaaggatg 201780 gattgttagt gatattgtgt gtgtatgtat gtgtttggga ggagtttata gtttttagtg 201840 gttttttaga ggggtttgtt ttgtatattt agggtttttg agatgatttt ggggagttta 201900 ggttggtttg gagtaggttt tgatgagtgg ttgttgtttt tgagtaatga tgttagtttg 201960 tgtagagggt tttgtggtag ttgttttttt attgttgttt tagtttggtt ttttaggttt 202020 tttattgtat tttattgtat tttggttaga ggttttttag tagtttagtt ttagttttgt 202080 tttggaattg gggttttgtg gtttttatat tttttggtgg ttttggagag ttggaggtta 202140 ttatgggagg ttgttgatta gtatgatttg ggtagggtga gggggttagg ttggagttta 202200 tagtgggttg tttgttgttt ttaaagtttt ttaggtttta tttaaatttt atagggattt 202260 tgtgaagggg gtgttttgtt ttttaggtag aagtgaggtt tagggaaggt tgttaaggtt 202320 ttttagttta tagggtagag aattgtagtt attgttttga tttttagaat tgtgttttgt 202380 ttattttatg gggtttaggg aggggtttgg ggaagtgttt ttgttaggtt atattttaaa 202440 taaaggtgag tttgtggggt ttttgtaagg tgtttgggta ttttttaggt tgggtttgtt 202500 tttttgattt ttgttagttg tgtatgtttt ttttgtttag ttttgtggat gtaaatttat 202560 atttgttagt ttgatatttt tttttttttt tttgtattga tttgggtttt ggtttttttg 202620 gggttttggt gttttttttg ttttttgtag ttttatggga tttggttgtt tatggttttg 202680 ttgtgtttat agttgtttgg aagttggtag tttgttttaa gggagggtgg aggtgtgggg 202740 ttttttttta tggtttttat tttgttttgt ttgttgtggg ggatgtgttt gtattttgag 202800 gatttagggt tgttttttgg gaagatggtt ggagagaaag agaggggaga ggtttaaagg 202860 tagtggttag gttgggattt atttttgtgg gttatggagg ggttgttttg ttttttagtt 202920 agggataggg tgagaaggat ttgggaattt ttgtgtttta gttatggtat aggttttttt 202980 ttggagtttt ggttttaagg agagggagag gtagtttagt agtttttgtt ttttgtggtt 203040 gttattgtga tagttttgtt ttttgggaat ggtgtgtagg aggttatttt atttgtttgg 203100 gtttttttgt ttttttaatt ttgagaagaa tagtggtttt gattttttat aaaattattt 203160 ttttttaggg atgttgagtg aggaataaga tgtggggtag ttttgttttt tttttttttt 203220 ttttttatgg tagttgtgtt tatttgtaga ggtgtaggta aggtggaggg gtatttgttt 203280 ggaggtttat agattttggg gagaatttta gttttgtttt aatttagtgg ggtgaggttt 203340 gtgtgttttt ttttgggttt tttttttgtg agttttagtt tttttgttta taaaatggga 203400 ttattttata aagtgagatt aagtgagtta ggttttgggt agggttttta ataggttgtg 203460 gttgtttgag aatttgtagt agtggtgatg gtggttgtgg tgatgaggat gatgggggtg 203520 gtaatgatgg tgatgatgat ggggtgatgg tgttagtgga gatgatgggg atgatggtga 203580 tggtggtggt gatagtggtg ggatggtagt ggtgatgtgg gtgatggtga ttgtgatggt 203640 ggtggtggtg gtgatggagg tgatggtgat agtgattatg agggtgatgg ggatggtggt 203700 ggtggtgatg gtgatagtgg tgggatggta gtgatgatgt gggtgatggt gatggtggtg 203760 atggtggtgg tggtgattgt ggtggtggtg gtgatgatgg tggtgatgat ggtgattgtg 203820 gtgatggtga tggtggtaat tgtgatggtg gtggtggtga tggtggtgat gatggtgatt 203880 gtggtgatgg tggttatgat ggtggtaatt gtgatggtgg tggtgatggt ggtgatgggg 203940 atgatgatgg tgattgtgat gggggtggtg gtggtgattg tgatggtggt gatgtgggtg 204000 gtggtggtga ttgtgatggt ggtgatgtgg gtggtggtgg tgattgtgat ggtggtggtg 204060 gtggttgtga tggtggtgat gtgggtggtg gtggtgattg tgatggtggt gatgtgggtg 204120 gtggtggtga ttgtgatggt ggtggtgatg gtggttgtga tggtggtgat gtgggtggtg 204180 gtgattgtga tggttgtgat tgtgatggtg gtggtggtga tggtgatgat ggtggtgatt 204240 gtgatggtgg tgatgggagt gatgttggtg attgtggtgg tgaagggggt gatggtggtg 204300 attgtgatgg tggtgaaggg ggtgatggtg gtgattgtga tggtggtgaa gggggtgatg 204360 gtggtgattg tggtggtggt aatggtgatg gtggtaaagg ggtgatggtg gtgattgtgg 204420 tgatgtgggt ggtggtggtg atgtgggtgg tggtggtgat tgtgatgggg gtgatgatgg 204480 taatgtgggt gatggtgatt gtggtggtgg tggtgatggt gatgattgtg atggtggtga 204540 agggggtgat ggtggtgatt gtgatggtgg tgattgtgat ggtgatgtgg gtgatggtgg 204600 tgttgatggg ggtgatgatg ttagtagtgg tggtgatagt gatggggatg atggtggtgt 204660 tgatggtgat agtggtggga tggtagtggt gatgtggttg atgatggtgt tggtgttgat 204720 gattgtgatg atagtggtgg tggtgatgag ggtgatggaa gtggtgatga tggtgggagt 204780 gatgggatga tggtaatagt agtgatggta ttgtgatgat ggtgttgatg gggatggtgg 204840 tgatgataag ggtgatgatg atggtgatga taataataaa agtaataata ataaagggat 204900 atattttgta gtattttagt tggtattttt tagatttaag gtgttgtggt tggaatattg 204960 atataatttt tgatttgagg ttggttagga tatagatttg gtggatagag agagatggat 205020 gaggagtgtt tgtttttggg ttattaaata gtttaggtta gggattttta gtattagttt 205080 ttgttttttt aggagtttat atttttttta gaaaggtgtt attaaagtta gaatattagt 205140 gtaatttagg gtgttttttg tgttgtgttt ttttgagata gggttttatt gttgtttagg 205200 ttggagtgta gtggtatggt tttgatttat tgtagttttt atattttggg tttaagtgat 205260 ttttgtgttt taggtatgtg ttattatatt tggttaattt ttgtgttttt tggtagagat 205320 agggttttat tatgttggtt aagttggttt tgaatttttg attttaagta atttattttt 205380 tttagttttt taaagtgttg ggattatagg tgtgagttat tttgtttggt tgatttttgt 205440 ttttttaaaa gatagggttt ttgttatttt ggagtggtaa tgattttagt ttattgtagt 205500 tttgtatttt tgggtttgag taattttttt attttagttt tttgtgtagt tgggattata 205560 ggtgtttgtt attatattta gttaatgttt atattttgat gtagagatag ggtttttttg 205620 tgttgtttag gttggttttg aatttttggg tttaagtaat ttttttgttt tagtttttta 205680 aagtgttggg attataggta tgagttatta tatttggttt agggtatttt ttttggtgtg 205740 ttgttagtgt agtttaaggt agttttgtgt agggtaaagt aatggggttt tgagtttgga 205800 ggggtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtatgtgtg tgtgtgttat 205860 atgtgatttg tttgtgtgtg ttgtgagagt tgtgtgtgag gtatgtgtaa gaggtatgtt 205920 tgaggtgagt tgtgtgtgtg ttgtgagttg tgtatgtgaa gtgtgtgtgt tgtgaggtgt 205980 gtgtatgagg tgtatgtgag ttgtgtgtgt tgtgttgtat atgaatgtta tttttttatt 206040 tttgtttgtt ttagttattt gtggattggt tgtttgtata tatggttatt gttttttgag 206100 tggtattatt ttgtaggtta gtgtttttta gtatatggtt ttatagattt tatgggatat 206160 gtgtgagttt gtttgatgtt tatattagtt ttatggggga aggattgttt attttatttt 206220 gtagattagg aaattgagat atggtgaggt taggtgattt gtttaggttt tggttggtta 206280 gggaggagta gtttgaatat ttgggttttg gttgtaatta ttttggtgaa ttgtaggaat 206340 tttggttatt tggtgtattt tgggtagttt tgggtttttt tgttagtttg gtttttgttt 206400 tgtttaaaat ttgagttatt aggagatttt ttgtttagaa agtataaggg gtataagaga 206460 tgttgatttt tttaggtttg gtttattttt taggagagga ttgtggtttg ggttgtgttg 206520 gtattagagt ttggttgtgt gggtttatat agttattgga tatttggttt gagggtgaag 206580 tttttggggg ttgtttggta gggatattgt tgggaggtag tttaggtatt gttgaatttt 206640 agattggaga gttttgtgtt tgggtgggag gggttttatg tgtagatttt gttggttttt 206700 ttggagagat ttttgattgg ttttttattt tttttttagg gtagagtggt ttgggtaaat 206760 ttattttaat taatattttt tttaaattta aaattagttg gaagttggtg tagtttattt 206820 tagaggagtg tatttttaag attattgaga ttaagtttat tatgtatggt tagtggttgg 206880 gagtgggttg ggggtgtagg atgtttttgt ttttttggag tataggggtt gggggttaag 206940 attattatat atagttagtg gttaggggtg ggttgggggt gtaggatttt tttgtttttt 207000 tggagtatag agtggggggt taagattatt atatatagtt agtggttggg agtgggttgg 207060 ggatgtagga tgtttttgtt tttttggagt ataggggttg ggggttaaga ttattatata 207120 tggttagtgg ttggggatgg gttggggatg tgggatattt atgttttttt ggagtattgg 207180 tgtggtgtga gggtgtttga gttaggtaat tttaggtttt taagatgggg atttgttgtg 207240 tttattattt ttagtatgtt gagtatgttg gggttttggt tgtgatgggt tagtgttttg 207300 gatttttgtg ggttttgtta tattgagttt tttatagata attgagtttt ttattaaaag 207360 tttgataggt aaggggtttt taggggaatt gttattggtt tgtgttggag ttggttgagg 207420 aaggttatta attttttggt gtttttttgg ttgttattgt tgtttatttg gggttgtttt 207480 ggggttagtt aggtgtgggg tgtttgtgag ggttttttgt tttttttttg attttgtgtt 207540 tgtggttttg tgtagatatt gaggagaaag gtgtttggat gaagttgata gtgattgata 207600 tattagggtt tggggattat attaataatg agaattggtg aggttttttt agggggagga 207660 gtattagtgg gggttttagg gttttttgga ttttatttag agttagtttt agaggttttt 207720 tggtttgtgg gggtgtaggg tttatttttt gggatttgat atgttgttaa agttgtatgt 207780 tttaggggtt tgaaaatttt ggattaaagt agaattattt ggggaatttt gttgttttta 207840 atttattatt tgaggttagt ttggggaggt tggtttggga ggttgagggt aaggttgtgg 207900 tatttttgtt tagtaagtta gattttttag ggtatgtatt ttattggaag gtggggtgtt 207960 gggttttgag ttttgggaat gtatgatttg tttggggagg gtattttatg tgtttgttga 208020 tttgttttta ttttttatgt agttggtagt ttattatgaa gtttattaat gattagtatg 208080 agaaatattt gtaggaggag gttaatatta attgtaagaa gtgtattttg gatatttgtg 208140 tttattgttg tttttatttt atttttgtta ttggttattt gtatgttttt gtagtgttgg 208200 tgtttttatg ttgggtgttt tgggtttttt ttgttttttg ggattgtaag atggtgttgt 208260 ttgttttgtt gttgggtgta gaggggttga gttaggggtt atggttgtta gttatgaagt 208320 tgggggtgtg ttatgtttgt atttttaaag ttttatattg atttttatgt aagtgttttg 208380 tttagttttt attttttagt tgtgttttgg ggagttgagg gttaggtagg ttttgggttg 208440 ttttggagtt tggtggtttg tgttttgttt ttttaggtta ggttttggta ggtggagtgg 208500 gagtttttag ttaagtattt gtagtggtga ttgatttttt tatttgggtt ttgttttatg 208560 ggatttttta gagggtttgg tgtgttttta gatgggaagt atagagatta gtgttggttt 208620 tttttagggt tggatggggt tgttgttggt gttggtgaga gttttttttt tttgttggtt 208680 ttgtttgtat ttgatgttgt ttttagagat tagtaagggt gggaggttgt atgtattttg 208740 gtaggtggat tttttatggt tttatggatt ttttgttttt agttttttgt gtattttttg 208800 ttagatattt gtggtttatt ttgagttagg gttgggagga ggaggattag aggttagtag 208860 gagtggttgg tggaggtagt tgtgggtggt ttgtttgtat gggtgggtgg agaaggtttt 208920 ttgtatttgt tgttttagat gtattttttt gggtggagga agtttagggg tttggggaaa 208980 ttatattttg tgggtattag gtgtaggaag gagtttggtt ggtgggtagt gggttttatt 209040 tagagtttgt gggaaaattt aagttggagt ttttgagttt attttttggt attatttttt 209100 gtgggttagt aggagttagg ggtagggggt tagtttgttg tttatgggtt ttttttgaat 209160 tgaatatttg tttttttagg tagaatggtt tatttgtggt tttgtggtag ttgttttagt 209220 tgttttaagt tttgttttag ttgaggttga tggtaggagg tagaagtttt ttttgatgtt 209280 agttgggtaa gttgagggtg ggtgggtggt ttgtggtatt tttgttattt tttagtattg 209340 attttttggt tgggatttta gttaggtatg ttgtttggtt ttgtttaagg tgtttagttt 209400 tatggggtag gggtgggttt tggttatttt tgtttaaatt tttgtttgga gtgggttttt 209460 ttttagttat gtgtgtgatt gatttatttt tattgtggga aaagtttggt tttagaattg 209520 gggaagatgg tgttttagtt ttagggtttt gttagttttt gttatttata gtttttttta 209580 tattagattt taggtttatt ggggttaagt aggtaagggg agtagtttgt ttggtgtagg 209640 ggagtagttt gtttggtgta ggggtattgt atattggtgt tagtttttat tttttttgtt 209700 tttttttttt tagttaaagt tttatagtaa gatggttgtt gagttaatga tagttttttt 209760 gtgtggatat gtaggggtgt ggttgggatt ttagaattta tggatgaggg tgtttggagt 209820 tggttttggt ttgtttggtt tgtgtagtgg tgttatttgt gtttgggata tatttgtgtt 209880 ttttttttgt tttatattta tagtgtggtt gatttggttt ggggttttgt ttttgttagt 209940 agggattttt gtgagttttg agttagtatt tgagagtgtt gatatttgtt tgggggtggg 210000 tgttttttta ttgttttgtt tttttagatg agttttatgt atattttttt gttttagttt 210060 taggtttttg gatattgagt ttatgaaatg tttgagtaag gtggttaata ttgtttttgt 210120 tattgttaag gtggatatat ttattttgga ggagagggtt tattttaaat agtgggtagg 210180 gttttatttt tatttgtttt agtttttttg tgtaatttgg agatgttgta ggtttggtag 210240 gggttatttt gtttaaagga gttatattgt tagggagatt gaattgttgg ttattttttt 210300 tagtgggtgg ttggtttggt ggtttttggt ttaggtggtt gttgggggtt gtttttgaga 210360 tggttttttt agttttttta tattttaaaa gtagttttgt gggagtgtta attttttagt 210420 agagtttttg aggggggttt tggagaagat ttggattagg tagatggtga attttttttt 210480 tagggagtga ggttgagtag gggttgtgtg atatggttta ttttgtttta tgtttttttt 210540 tttttttttt gagaaagggt ttggtttagt tgttaaggtt gtaatgtagt ggtataatta 210600 tggtttattg tagtttttat tttttaggtt tagtttttga gtagttggaa ttatagatgt 210660 atattattat gtttggttaa tttttgtatt tttagtagag atgaggtttt gttatgttgt 210720 ttaggttggt ttttaatttt tgggtttaag ggattttttt gttttagttt tttaaagtgt 210780 tggggttata ggtatgagtt attttatttt gttttgtttg gtttttatta gatggaagag 210840 aagttgggtt aggtgtggtg gtttatgttt gtaattttag tattttggga ggttgaggtg 210900 ggtagattat ttgaggttag gagtttgagg ttaatatgat gaaattttat ttttattaaa 210960 aatataaaaa tattagttgg gtatggtggt gggtgtttgt agttttagtt atttgggagg 211020 ttgaggtagg agaatttttt gaatttggga ggtggaggtt ttagtgagtt gagattgagt 211080 tattgtattt tagtttgggt gatagagtga gattttattt taaaaaaaaa aaaaaaaaaa 211140 aaagttttag gagggatggt ttttgttatt tttttttttg ttattgtttg aggtttttgt 211200 tgtgggatag ggaggggtat ttaagtaaga gggtagtttt gggttttttt ttttgatagg 211260 gtagtatatt agagttatat ggggtgtttt ttaaaatgaa attgaggtgt ttgggttgtg 211320 gtattatatt tgttttggtg ggtgtgggtg gggtttgtaa tttattttgt tttggggtta 211380 ggtgttaggg atttttttag tatgtgtagg ggaagatagt ttatataaag tgggtgtgtt 211440 tgttggaggt tatatatggg ttgtggtttg tgtttgggta ggtgagtagt tgtttattgg 211500 gatgtttttg ttgtatgtat ttatgttggg ttgttggtag ggagttgaga ggttattgta 211560 ggtggggttt ttgttggaat tggggattgt gatgagggtt ttttaggaag ggttttagga 211620 ggggaggttt tggtaatttt gagtattttt ttggggttgt gatgagtagg agaagagagg 211680 tgggaggtgt ttaggatgat gattttaagt ttttggggag ttgtagtgtt gtttaggata 211740 gtaggtgtat ttgtagttgt tttttttttt tttaggaggt ataggagttg gaggtgattg 211800 gtgttatagt tttttagagt ttgtttttga atttgagttt ggggtagtat atagtgtgga 211860 ggttatgtgg taaatattag tgggtgggta gagtttgtta tagggatggg tttatttttt 211920 ttttttttta ttttagatta ttgtagattt gttgtttaat ggtattgatg tgtattttta 211980 gaaggaattt gatgaggatt tggaggattg gttggtgaat gagaagtttt gggtgagtgg 212040 atttattagg atgttgtttt taggggattt ttagtttttg ttgaagggtg ggttgggggt 212100 ttggaggatt ttaagttatg aaattatatt tttggggtta gagggtattg agtttaggtg 212160 tttgtattta gtgttgttag gttgaggttt ttgtttttgg gggattttag gtttagggta 212220 gttttttttg ggggtttagg ggagggaatt gtttttttgt atatgtgtaa ttaatattgt 212280 ttgtttgttt tttaggagat gattttattt gttgtggtgg gtagtgatta tgagtattag 212340 gttaatggta agaggatttt tgggaggaag attaagtggg gtattattga aggtatttgt 212400 tgtaggtgtt ggggttttag atagatggga agatagtttt ttttgttgat ttagagtttg 212460 tgggttatgt ttgagttagg gatttgtgga attttattta ttgttttgtt ttatttagag 212520 ggaggggttt ttttgttttt atttaatttt tgggaaagtg agagggtaag tggtttgtgt 212580 agatgttttt attttagatt tttttttggg tagggaaaga tttagggaga taggagttgg 212640 gatgggggtt gttaagtttt ggattttggt gtaggttttt ttataggtat ttgtgtggtt 212700 ttggataaat tgtttaattt ttttgggttt agaaaagggg tgggttgtag ttttgtgagt 212760 tagatggatt tttggttttt tattttgttg aagtttttgg gatttttata ttttagtttt 212820 ttgagtggtt gttgtaatta attagtataa atgaggggat ttaaaataat ataaatgtat 212880 ttttatagtt ttagaggtta gaggtttgaa attaggggtt gttttttttt gaggttttga 212940 ggattagttt tatttatgtt tttttttttt tggtggtgtt tggtattttt agttgtattg 213000 taaaggtatt atatgtttta atttttgttt tattgttata gggttttttt ttttgtgttt 213060 ttgttttgtt tttttttttt tttttttttt tttttttttt ttgtttgaga tggagttttg 213120 ttttgttatt taggttggag tgtagtgttg taattttagt ttattgtaat ttttgttttt 213180 tgggtttaag taattttttt gttttagttt tttgagtatt tgggattata gttatgtatt 213240 atttatttga tttaattttt gtatttttag tagagatagg attttgttat gttggttagg 213300 ttggttttaa atttttgatt ttaggtgatt tgtttatttt gtttggtttt ttaaagtgtt 213360 gggattatag gaatgagtta ttgagtttgt tttttttttt ttttgttttt ggataaggat 213420 gtttgttttt ggatttaggg tttattttaa gtggatgatt ttatttggag atttttaatg 213480 aatttataaa gaaagatgtt ttttaagtaa ggttataatt atgggtttta aggtttggat 213540 tttgattatg tttttgaatg gatgggagtt tttggggggt tatagtttaa tttatttttg 213600 gtggtgatat tttgggaggg atgggtttga atgttttttt tttttttttt tttttgtttt 213660 tttatttttt attagaatgg aagaggggaa ggtgtagagg gaaatgtagt aggaaaagtt 213720 attttgtttt gggagagtat ttggttgaaa ggtttagtag agtaggaagt ataagttttt 213780 taatttttta gggttttagt ttttattatt tataaagtgg gtgtagtgtg ttaagatttt 213840 agtgagttga gagattgttt taaagattat agagtttttt gggaagttgt tgttttaaaa 213900 aaatggttat aatgataatt attaggaggt attagatatt tttgtgttat tggttagata 213960 tgggttattt tgttttatgt ttgaagtttt ttgtatttat tttttttgta gagttgaaga 214020 ggtgttgtga gtagaaaatt tgttaaggga tttagaatgg gaggtggttt tagaatttat 214080 agttttagtt ttgtattaga tttttttgag atgggagttt atgtttggag gagggtgtgg 214140 agaggtatat gggttttttt tttgtttgta tttttttttt attattattt ttgttgggtt 214200 tattttgtgg gagttgttta gttgggtgta gtttgggtgt tttttagtat ttgtttgtgg 214260 tgttaggttg gtttgttttt ttttggtttt tttgtttgta gttttttttt ttttttttgt 214320 ttaaagagtt tttgttgttt aggaaatttt ttatgaaagg taggtttggg agagttaggg 214380 atggatgggt ttgggatggg ttggtggttt tgttatgggt gtgtttttgt tgtattttgg 214440 tggttaattt tgagtattgt aggtggttgg tgatagaaat tgttaggaaa tgtataagag 214500 agaggttttt gtattttttt gatttgtgtg ttgttgagta ttattggttt tagttgagga 214560 agagtttgga atttgttagg atagttgtga ggtggtgggg tttatttttt agtagtttta 214620 tatgaggatt ttggaaatgt gtttttagta ttgttgggtt tttatattag gggttttatg 214680 agtttatagt tgatttgata tttggattag taagggttgt gttttgtttt tgttttttat 214740 ttggtgaata gtattttgag gtattttttt tatttttaga aattatttta agtattgtta 214800 atagaaatgt ggggtgtaat tgattatgtt atgaatttat ttaattttta tgtttttgag 214860 aggtgggtga tgttattatt tatattttat ggatgaggaa attgagggaa tgagagtaat 214920 ttgtttgagt tagggagtgg tgattatata ttttaatttt agtttgagag ttttattttt 214980 tttgttggtt tttgttgttt gttagtgtta gatgagagtg ttgttggtta gtttgtagga 215040 ggttttagtg tggatattgt tttatatagg gttgtggtag gagggtttag gtaaaggtaa 215100 ttggtatagt attgagagta tttgagggtt gggtaaggtg gaggttttgg ttttgtttgt 215160 tggtttatta agtaaaaatt agatattttt aatttgggga aaagttatgt ggttttgtga 215220 tggggtagtt tggagttagg tgtatgggtt ttgtattttg ttttagtttt atgtattgtg 215280 gagttgagat agatatagtt tttgtgtttt ttatgtttta tttttttttt tttttttttt 215340 tttttttttt tttttttttt ttgagatgaa gttttatttt tttgtttagg ttggagtgtt 215400 gtggtgtgat tttggtttat tataattttt attttttggg ttttagtgat ttttttgttt 215460 tagttttttg agtagttggg attataggtg tttggtatta ggtttggtta atttttgtat 215520 ttttaataga gatgagattt tattatgttg gttaggttgg ttttgaattt ttgattttgt 215580 gatttattta ttttagtttt ttaaagtgtt gggattgtag atgtgagttg tggtgtttag 215640 tgtttatgtt ttatttttgt aagataatgg ggataataaa ggaattataa gagatatttg 215700 taggtgtgtg aagatgaagt ttattatatg ggagggtatt gggtgttttt atttgttttt 215760 tttgtttggt tttttatttt tagtgatgtt gtttattgtt ttttttgtta aaaggttttt 215820 tgttatataa tagttatata tgttaggtat tgtgtgttta tataggagtt atgaagtata 215880 gtaataaaat gattattttg agatggttat tagtttgagt ttgagggtat ttgtgggtgt 215940 ttgtggtttt ttgtttagtt tttttgagaa gtggttattg ttttgagttt gggtttgtat 216000 gtattgtgtg aagtgtatat gtttttgagt aatgtttagt attgttgatt tttgagtttg 216060 tgaatggttg tttatagtat gtagtttttg tgtgtgtttt tgtgtgtgtg tgttttgagt 216120 gtatataagg tggatggggt tgtgggggta atattttgtg ggttataggt tttttttaaa 216180 attttagttt tgatttttgt tttattttat ttttagtagt ttagtttttt gtttgttttt 216240 aggtttttgt tgggatgttt tgtttttttt ggttatttta gtggtgtggg ggtttattgt 216300 tttggttttt ttattgtggt ttttttttat gtttttattt ggtttggtta ttgtgttatt 216360 ttttattagt taggaatttt ttggagagta ggagttgagt tgtttaggag taggagttgg 216420 tgttggttat tttagtattt tttagattga gggtagtgtt aggtgtttta tatttagttg 216480 tagagtaggt ggtttttttg tttttttgtt tatggggttg tttttagatt ttgtttttgg 216540 tattagtatt tttgggtagg gggagagagg tggggtttgg gtagagtttt tttattggga 216600 tattaaagtt ttttttgttt ttttttttag ttgaaaatat tatatattgt gagtttgttt 216660 atttgtggga tttttttatt aggtgagaga tagggtgttt gggtggggtt gatggtttta 216720 tttttaagag ggttttatag tgggtggggg tagtgggtgt ggggttgaag ttttgggtag 216780 agtgggtgtt ttttgttatt tgtttgtttt gtttttggga agattttgga agtttatttt 216840 ttgaaaaaga aaatttattg ggaaatgaag taggtagtga agattttttt taatttttgt 216900 gaagttggtt ggatgggaag gttgagtttt gatttattgt ggtttggttt gttagagttg 216960 tttggtggtt attaagggtt tagtgaggtt ttatgtgtag gttttgttgg tagtgtgggg 217020 tgtttttagt tttgatttta ttggtttttg atttttattt tttttatttg gttgaggttt 217080 ttttttgttt tttttgagtt taggtaagga ggggaagttt tgatggagag ggtgttgggt 217140 gggtggtttt tggagtgtgg gttttggttt gggtaggttt ttttttagta agtagttggt 217200 atggatgatg ggaatgttat taagaggagg ggtttttagg ttggtggggg taggggtggg 217260 gggattttgg gagttgtttt gttattgtgg ggatattggg ttttttaatt tttttttaga 217320 ttattttttt tgagttgtag aggaatgaaa atttgagttt aggatttttt ttttttgggg 217380 ataagggtaa tttagttttt tgttttaggt tatttgtttg ttataggtta tagttttgga 217440 ggttggtggt tatttattgt ttttattttg ttagtatttt ggatattggt ttggagtaat 217500 aatgttttag ttttgttttt ttgagtttat gtattgtttt tgggttttgg atttagggtt 217560 atagggtgga tttagaggga gatatatgta ttggaatatg tgtgttttga ttgagtttgg 217620 gtttattagg gggattgatt ttttttttaa aatgtgtatt agatttggtt taatatggtg 217680 ggtttggggg attttatggg gagttaagta gttgggatgg ggagtggggg tgggggtagg 217740 tgggtttgag tttgaggtag gttgagtagg gtttttgttt tgttgttttt attttgttgt 217800 gtttatttta ttgatttgtt tgttttttat ttttatagga tgtatatgta gaatattaag 217860 gatattatta gtagtattta ttttgaggtg tattgtgtga agtgttttaa tgagggtagt 217920 agtgttatgg ttaatggtat ggaggagaag gagttagaag ttttggagat gtagatgtta 217980 ttttgtttat ttttgggatt ttgtttttaa gttatttttg ttttttttta ggttttttta 218040 ttattttatt ttattttata tgattttttt tatttgttat tgttttttat ttttttgata 218100 tgttgttagg aaataaggga aggggttttt ttttgagtga gttagtgatg aggttgtggt 218160 ttttttgagg ttgtggggag gttgtattgg agttataggt aggggtgaga gtatttattg 218220 aattgatatg attttttgtt tttaggtttg gttttttgag ggtttagaag agtagttttg 218280 gtgtgtagat tatttgtttg tgtggggttt ttagtgttgg aggttttggg gtgggggtta 218340 ggttttgtat ttgtagagga gtttagtggg ttgtatgttt ttttttattt ttattggttt 218400 tgttttttgg agtgtgttag agtttagggg agaatgtagt ttattaggag tatttggatt 218460 ttttgtttgt tatatggtgt ggttattatt tagtttttat ttttgttttg tttttaaggg 218520 tagaaaattt tagggttttt tgttattgat tgtttagtta ttttaagttt tttggtagtt 218580 gttttttttg gagtagaaag tgtttttatt ttagttattt gtagattgtt tggttagatg 218640 tggggatagg ttggaatgag ggaggtgttt ttattttttt gttatttttt ttttatgtta 218700 tttttgtttt tattgggttg taggtgttgt tgatgtgttg ggatttgatt gaggataaaa 218760 aggaaggaga gatgattttt atttttttat tttttagttt tgaaaaggtt taagtaagtg 218820 agtttggtgg aggagttgag ggagggagtt atggaaggtg ttagaaggaa ggttggtggg 218880 ggtatgtgtg ggttgtggtt tgggttggtt agagtggtgt gagttgtttg gtgtttgttt 218940 tgtttaagtg attagggaag tgtgtgtgtg tttatgtgta tgtgtgtttg tttgtttgtt 219000 tagtgtttgg gtttggttta agattgggtt gtagttatat taatgtttag ttagttattt 219060 ttgttattta ttttttttgg tttaggtttt gttgattttt tgagttgggg aggtgggagg 219120 ttaggtgagt ttgattttgt tgatttattt gtgtttgggt tttttttttt agagtttatg 219180 gtaatgaatt tttagaaagg agagaatggg tgttaggggt gtatagttta tagttgaaga 219240 gtaaggtttt gtggtagtat ggtttggttt tttatttttt gtttttatga ggggatttat 219300 gggggttgtt tttgtagggt atagatgatt aaagtttttt tttgtttttt gttatttgtt 219360 ttgtttttgg ggagaaagag gggtttgatg agattttatt taggtgtata tattattagg 219420 tgtatttgta ggtattgggt tggttgtttg tagttaggag aaggttagtg agaaggagtg 219480 tatgagtgtg agtgtgtgtg tatggaagtt ggggtattgg gtgtttgatt ttttttttat 219540 ttaagagagg aaggattttt tattattttt attggtgaga tagtttattt tgttaatttg 219600 ttatgttttt gttaaaatta agattttgaa ggaaatgagt ggttagtgtt agggtttagg 219660 ttatgtggtt tgtttagttt taatgttatt tggtggtggg gtggggtggg ggtgggtagt 219720 agtattttag ttttgagatg ttttattttt tttttttgta attagatttt gaaaaattgt 219780 ttgttttatt aggttttgtt ttttaatggt tttttgttat gtgttttttg agaaatttgt 219840 ttttttgtat aaatgataaa gtgttgaaaa tgtatttttt gaaataaatg ttttaaatgt 219900 agaaattta 219909 <210> 11 <211> 219909 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 11 tgggtttttg tatttgaaat atttatttta ggaaatatat ttttaatatt ttgttattta 60 tataaaaaga taaatttttt gggaggtatg tagtaaaagg ttattgagga atagagtttg 120 atgaaatgaa taatttttta aagtttggtt atagagaagg aaagtgaagt attttaaggt 180 tgggatgttg ttgtttattt ttattttatt ttgttattaa gtgatattga ggttgggtag 240 gttatatggt ttgggttttg gtgttggtta tttatttttt ttaaaatttt ggttttggta 300 aaaatatggt aagttggtaa agtaaattgt tttattagtg ggggtggtga ggggtttttt 360 tttttttggg tggggaggga gttagatgtt tagtgtttta atttttatgt atatatattt 420 atatttatat attttttttt gttgattttt ttttggttgt aagtagttag tttggtgttt 480 gtagatgtat ttggtgatgt gtgtatttga gtggagtttt attaggtttt tttttttttt 540 taggagtaag ataggtaata ggaagtagga agggattttg gttatttgtg ttttgtaaag 600 atagttttta tgggtttttt tgtggggata gagggtgagg ggttgggttg tgttgttatg 660 aaattttgtt ttttagttgt ggattgtgta tttttgatgt ttgttttttt ttttttaggg 720 gtttgttatt atgggttttg aggggagggg tttaggtatg ggtagattaa tagagttagg 780 tttgtttggt tttttatttt tttagtttag agagttagta aggtttgggt taggaagggt 840 gagtggtagg ggtggttggt tgggtattaa tgtaattata gtttagtttt gggttaaatt 900 tagatattag atagatagat ggatatgtat atatatggat atatatatat ttttttggtt 960 atttgggtag ggtaggtgtt gggtagttta tgttattttg attagtttaa gttatggttt 1020 atatgtgttt ttgttaattt tttttttggt attttttatg gttttttttt ttagtttttt 1080 tattagattt atttgtttag atttttttaa aattggggga tgagggggta ggggttattt 1140 tttttttttt tttattttta attagatttt agtgtattag tagtatttgt agtttggtgg 1200 gggtgggggt ggtgtgagag ggggatggta gggagatgaa gatgtttttt ttattttagt 1260 ttgtttttgt atttggttaa gtagtttgtg gatggttgag ataaaggtat tttttgtttt 1320 aggaggggta gttgttaggg ggtttggagt ggttgggtag ttggtggtag gggattttgg 1380 agttttttat ttttaggagt agggtagggg taggggttga gtgatggtta tattatgtgg 1440 tgggtagggg gtttaggtgt ttttggtggg ttgtattttt ttttgggttt tgatatattt 1500 taggggatag ggttgatggg gatggagggg agtgtgtagt ttattgggtt tttttgtaag 1560 tgtgaggttt ggtttttatt ttaaggtttt tggtattgag aattttatat agatggatga 1620 tttgtatatt gaagttgttt ttttgagttt ttggggagtt aggtttgggg atagagggtt 1680 atgttaattt agtgggtgtt tttatttttg tttgtggttt tagtgtagtt tttttataat 1740 tttggggagg ttgtggtttt attattgatt tatttggagg gaggtttttt tttttgtttt 1800 ttggtagtat gttgaagggg tggggaatga tgataaatgg agaaaattat ataaaataaa 1860 atggggtggt gggagggttt ggggggggat ggaaatgatt tgggggtagg attttggggg 1920 tgggtagggt ggtgtttata tttttggggt ttttggtttt ttttttttta tgttgttggt 1980 tatggtgttg ttgtttttgt tgaggtgttt tatatggtat gttttgaagt ggatgttgtt 2040 ggtgatgttt ttgatgtttt gtatgtgtgt tttgtggggg tggggggtgg gtgggttagt 2100 gaggtgggtg tagtggggtg ggggtagtgg ggtaggggtt ttgtttggtt tgttttggat 2160 ttaggtttgt ttgtttttat ttttattttt tattttgatt gtttggtttt ttatggggtt 2220 ttttaggttt attatgttgg attagatttg gtatatgttt tgggggaagg gttagttttt 2280 ttggtaagtt tagatttggt tagaatatat atattttagt gtatgtgttt ttttttgggt 2340 ttattttatg gttttgggtt tagggtttag ggatagtgta tagatttaga gggatagggt 2400 tggagtattg ttgttttagg ttggtgttta gggtgttggt agggtggaag tagtgggtga 2460 ttattggttt ttaggattat ggtttgtggt aggtaggtgg tttggggtaa agggttgggt 2520 tgtttttgtt tttaggaaaa aaaagttttg ggtttggatt tttatttttt tgtagtttag 2580 gaggaataat ttggagggag gttggaaagt ttagtatttt tataatggta gaatggtttt 2640 tggaattttt ttatttttgt ttttgttaat ttggaggttt ttttttttga taatattttt 2700 attatttatg ttagttgttt gttgaggaag aatttgttta ggttagggtt tatattttag 2760 ggattattta tttagtattt tttttattag ggtttttttt ttttgtttgg atttaaggga 2820 aataaggaga agttttagtt aggtgaaagg ggtaggggtt agaggttagt gggattggag 2880 ttggagatgt tttatgttgt tggtagggtt tgtatatgag gttttattgg gtttttagtg 2940 gttattgggt agttttaatg ggttagatta tagtggatta aagtttagtt tttttattta 3000 gttaattttg taggggttga aaaggatttt tattgtttgt tttatttttt agtgggtttt 3060 tttttttaga agatgggttt ttaagatttt tttgagggta gggtaggtag gtggtagggg 3120 gtatttattt tgtttagggt tttggtttta tatttattgt ttttatttgt tgtagggttt 3180 ttttaggggt gaagttgtta gttttattta agtattttgt tttttatttg atgagaaggt 3240 tttgtaggta ggtaaattta tagtgtgtgg tgtttttaat taggagagga gataggaggg 3300 gttttaatgt tttagtggag aaattttgtt tggattttat tttttttttt ttgtttagaa 3360 atgttggtgt taaaagtaga gtttgagggt agttttatgg gtaggagggt aggggaatta 3420 tttgttttgt agttgagtat aggatatttg gtattgtttt tagtttgggg gatattggag 3480 tgattagtat tagtttttgt ttttggatag tttagttttt gttttttaga aagtttttgg 3540 ttaatgggag atggtatagt gattaggtta aataggagta tggaaggaag ttatagtgga 3600 gaagttaggg tagtgggttt ttgtattatt ggggtgatta gggagagtag gatgttttag 3660 taggggtttg aagataggta gggggttggg ttgttgggaa tgggatgaag taggaattgg 3720 agttgggatt ttaaagaaaa tttgtggttt atagggtgtt atttttatgg ttttatttat 3780 tttgtgtgtg tttagagtat atatatatag ggatatatat aggggttatg tattgtggat 3840 gattatttat aagtttaaga attagtaatg ttaaatattg tttagggata tgtgtatttt 3900 atataatata tataagttta agtttgggat agtggttatt ttttagggag attgggtagg 3960 agattatggg tatttataag tgtttttggg tttgagttgg tggttatttt agagtggtta 4020 ttttattgtt gtgttttgta atttttatat gaatatgtgg tgtttggtat gtgtaattgt 4080 tatataatag aaggtttttt aataaggagg gtagtgaatg gtattattgg aggtggggag 4140 ttgggtaggg aaggtaaata aagatatttg gtgttttttt atgtgatgaa ttttgttttt 4200 atatatttgt aagtgttttt tgtgattttt ttgttatttt tattatttta tgaaaatggg 4260 gtgtagatgt tgggtattat ggtttatgtt tgtaatttta gtattttggg aggttgaggt 4320 gggtggatta tgaggttagg agtttgagat tagtttggtt aatatgatga aattttgttt 4380 ttgttaaaaa tataaaaatt agttaggttt ggtattaggt gtttgtaatt ttagttattt 4440 aggaggttga ggtaggagaa ttattggaat ttaggaggtg gaggttgtgg tgagttaaga 4500 ttatgttatg gtattttagt ttgggtaaaa gagtgaaatt ttgttttaaa aaaaaaaaaa 4560 aagaaaaaga aaaagaaaag aaaagaaaat gaggtataga gaatgtaaga attgtgtttg 4620 ttttagtttt atagtgtata aggttggagt gggatgtaga atttatatat ttggttttag 4680 gttgttttat tgtagagtta tatggttttt ttttaagtta aaaatgttta gtttttattt 4740 ggtaggttag taggtagggt tggggttttt attttgttta gtttttaagt gtttttagtg 4800 ttatgttggt tgtttttgtt taggtttttt tgttatggtt ttgtgtaggg tggtgtttat 4860 attagaattt tttgtagatt gattagtagt atttttattt aatattgatg ggtagtgaga 4920 gttggtagga agaatggggt ttttaggttg gagttggagt gtgtgattgt tattttttgg 4980 tttgggtaag ttatttttat ttttttagtt tttttattta taaaatgtgg ataataatgt 5040 tatttgtttt ttagggatat gaggattaaa tgagtttatg gtgtgattaa ttatatttta 5100 tatttttatt gataatattt ggggtggttt ttaaggatgg gaaagatatt ttaagatgtt 5160 gtttattaag tgggaggtaa gaataaggta tagtttttat tagtttgggt gttaggttag 5220 ttatgaattt atggggtttt tgatataaaa atttagtagt gttgaaggta tatttttagg 5280 gtttttatat aagattgttg gaaagtgggt tttattattt tataattgtt ttgataggtt 5340 ttagattttt ttttagttgg agttagtggt gtttaataat gtataggtta gagaggtgtg 5400 gggatttttt ttttgtgtat tttttgatag tttttgttat tggttatttg tggtatttaa 5460 ggttggttat tagggtgtag tagaggtatg tttatagtaa agttgttggt ttgttttagg 5520 tttatttatt tttaattttt ttaaatttgt tttttataaa aagtttttta aatagtaaga 5580 attttttggg tagagaggaa gagaggaatt gtaggtagag gggttaaggg gaggtaagtt 5640 agtttgatat tataggtgga tattggaaaa tatttaggtt gtatttagtt gggtagtttt 5700 tgtagggtgg gtttggtagg ggtggtggta ggggaggagt gtagataggg gaaaggtttg 5760 tgtgtttttt tatatttttt tttaggtatg aatttttatt ttgagggagt ttggtgtagg 5820 gttggagttg tagattttag agttgttttt tgttttgggt tttttggtag gttttttgtt 5880 tatagtattt ttttaatttt gtaaggaggg tgggtgtggg gagttttgga tatgaaatga 5940 gataatttat gtttagttag tggtatagga gtgtttgatg ttttttggta attgttatta 6000 tgattatttt tttagagtaa tagtttttta aaaagttttg tggtttttgg gatagttttt 6060 taatttatta aaattttggt atattgtatt tattttgtgg atgatgaaaa ttgaggtttt 6120 ggaagattaa gagatttgtg ttttttgttt tattgggttt tttagttaag tgttttttta 6180 gaataaagtg gttttttttg ttgtattttt ttttgtattt tttttttttt tattttaatg 6240 agaaatgaag ggatagagag aggaagggga aggaaatgtt tgggtttatt ttttttgggg 6300 tgttattgtt aggagtgggt tgaattgtgg ttttttaggg gtttttattt atttaaagat 6360 atggttaagg tttaggtttt ggaatttatg attgtgattt tatttggaaa atgttttttt 6420 ttatagattt attaaggatt tttaaatggg attatttatt tagggtaggt tttaagttta 6480 aagataggta tttttgttta aagataagaa ggaaagaggg taggtttggt ggtttatttt 6540 tgtaatttta gtattttggg aggttaagta aggtgggtag attatttgag gttaggagtt 6600 taagattagt ttggttaata tggtgaaatt ttgtttttat taaaaatata aaaattaagt 6660 taggtgggtg gtatgtgatt gtaattttag atatttggga ggttgaggta ggagaattat 6720 ttgaatttag gaggtagagg ttgtagtgag ttgagattgt aatattgtat tttagtttgg 6780 gtgatagaat gagattttgt tttaaataaa aaaaaaaaaa aaaaaaaagg aagaggaggg 6840 atgggataga gatataggga agaaggtttt gtgataatgg ggtagagatt agagtatgtg 6900 atgtttttat aatataatta ggaatgttag gtgttattag aaggaggaag gtatggatga 6960 ggttggtttt tagggtttta gaaggaaata gtttttgatt ttggattttt ggtttttgga 7020 attgtgaaaa tatgtttgtg ttgttttaag tttttttgtt tgtgttaatt ggttataata 7080 gttatttaag agattaaggt gtgagggttt taggaatttt agtagggtaa ggggttgagg 7140 gtttatttgg tttatagagt tatagtttat ttttttttta ggtttagaga ggttgggtga 7200 tttgtttagg gttatatagg tgtttatgaa agagtttgta ttaggattta gaatttggtg 7260 gtttttattt tagtttttgt ttttttgaat ttttttttgt ttggggggag gtttggggtg 7320 gaggtatttg tataggttat ttgttttttt atttttttaa gggttgaatg gggataagga 7380 gatttttttt tttgggtggg gtaaggtagt ggatgaggtt ttatgagttt ttggtttagg 7440 tgtggtttat aggttttggg ttagtagaag agattgtttt tttatttgtt tggagttttg 7500 gtgtttgtgg tgagtatttt tgatggtatt ttatttggtt ttttttttaa ggattttttt 7560 gttgttgatt tggtatttgt ggttattgtt tattatagta aatgggatta ttttttgggg 7620 aatgggtaga tggtattggt tatatatgtg tgggaaggta attttttttt ttgggttttt 7680 gggaggagtt gttttgagtt tggggttttt taaaaatgag agttttagtt tgatagtatt 7740 gggtatagat atttgggttt agtgtttttt ggttttaaga atataatttt atggtttaag 7800 gttttttaaa tttttaattt attttttagt aggaattggg ggttttttgg gaataatatt 7860 ttagtggatt tatttatttg gaattttttg tttattagtt ggttttttga gtttttatta 7920 aatttttttt gggggtatat gttgatgttg ttggatagta ggtttgtggt gatttgggat 7980 aaggagggag agagatgggt ttatttttgt ggtaagtttt atttatttat tggtgtttgt 8040 tatatgattt ttatattgtg tgttgtttta ggtttgggtt taagggtagg ttttgggggg 8100 ttgtgatatt aattattttt aatttttgtg ttttttggag ggaagagggg tagttgtagg 8160 tgtatttgtt gttttgagtg atgttgtaat tttttagggg tttaaggtta ttgttttgag 8220 tattttttat tttttttttt ttgtttatta tagttttaag aaagtattta gggttattga 8280 gatttttttt tttgaaattt tttttaaaaa atttttgtta tagtttttag ttttagtagg 8340 ggttttgttt gtagtaattt tttagttttt tgttagtagt ttgatatggg tatgtgtaat 8400 agaaatattt tagtgagtgg ttgtttgttt gtttaggtat agattatagt ttgtgtgtag 8460 tttttggtag atatatttat tttgtgtgga ttgttttttt ttgtatatgt tgggaaggtt 8520 tttgatattt ggttttagga tggagtaggt tataggtttt atttatattt attgaggtag 8580 atgtggtgtt gtagtttagg tattttggtt ttattttgaa aggtatttta tgtggttttg 8640 atgtgttgtt ttgttaggag gaagagttta gggttgtttt tttgtttgga tgtttttttt 8700 tattttatag taggggtttt agatggtggt ggagaagaag gtggtagaga ttattttttt 8760 tgaaattttt tttttttttt ttttttttga gatggagttt tgttttgtta tttaggttgg 8820 agtgtagtgg tttaattttg gtttattgaa gtttttgttt tttgggttta agagattttt 8880 ttgttttagt tttttaagta gttgggatta taggtgtttg ttattatgtt tgattaatat 8940 ttttgtattt ttagtagaga tggggtttta ttatgttggt tttaaatttt tgattttaag 9000 tgatttgttt gttttggttt tttaaagtgt tgggattata ggtgtgagtt attatatttg 9060 gtttagtttt ttttttattt aataaaaatt aggtagggtg aggtgaggtg gtttatgttt 9120 gtaattttag tattttggga ggttgaggta ggaggatttt ttgagtttaa gggttagaga 9180 ttagtttggg taatatggta aaattttgtt tttattaaaa atataaaaat tagttagata 9240 tggtggtgtg tgtttgtaat tttagttatt tggggattga gtttgggagg tggaggttgt 9300 agtgagttat gattgtgtta ttatattgta attttggtaa ttgagttaga ttttttttta 9360 aaaaaaaaaa gggggggtat aaaataaggt gggttatgtt gtatggtttt tgtttggttt 9420 tattttttgg aagagagatt tattatttgt ttggtttagg ttttttttaa aatttttttt 9480 agagattttg ttggagaatt ggtattttta taaagttgtt tttgagatat gggggagttg 9540 gagaggttat tttagggatg gtttttagta gttatttggg ttagggatta ttaggttagt 9600 tatttgttgg ggagagtgat tagtggtttg gtttttttga tagtgtgatt tttttagatg 9660 gggtggtttt tgttaggttt gtagtgtttt taggttgtat agaagggttg gggtaagtag 9720 agatggaatt ttatttgttg tttgaagtgg attttttttt ttagggtgag tgtgtttgtt 9780 ttggtgatga tagggatgat gttgattatt ttgtttaggt gttttataaa tttgatgttt 9840 aggggtttga ggttgaagta gagggatgtg tgtgaggttt atttggggga gtggggtagt 9900 gggggggtat ttatttttaa gtaggtgttg atatttttag gtgttggttt ggggtttatg 9960 ggggtttttg ttggtaagga tagggttttg ggttgagttg gttatgttgt gagtgtgggg 10020 tagaggaagg atatgggtgt gttttagata taggtgatat tattgtatag gttaggtggg 10080 ttagggttag ttttaagtat ttttgtttat gagttttggg gttttaatta tatttttata 10140 tgtttatata gaagggttgt tgttggttta gtagttgttt tgttgtgggg ttttggttgg 10200 gaggggagag gtaagagaaa tagaagttag tattagtgtg tggtgttttt gtattaggtg 10260 ggttgttttt ttgtattagg tgggttgttt tttttgtttg tttggtttta gtgagtttgg 10320 ggtttgatgt ggggaaagtt gtgggtggta ggggttggta gggttttgga attggggtat 10380 tatttttttt agttttggag ttgagttttt tttatagtga gaataaattg gttatatata 10440 tggttgggga gaagtttgtt ttgggtagaa gtttaagtag agatggttaa ggtttgtttt 10500 tgttttatgg gattggatgt tttgggtggg attaggtaat atgtttagtt ggagttttag 10560 ttaaagggtt agtgttgggg agtggtagaa gtgttataga ttgtttgttt gtttttggtt 10620 tgtttagttg gtattaggag aggtttttgt tttttgttat tagttttagt tgaggtaaag 10680 tttggagtag ttggaatagt tgttatagga ttgtaggtga gttgttttgt ttgggagggt 10740 agatgtttag tttaggagag gtttatggat agtgggttgg ttttttgttt ttgatttttg 10800 ttggtttata gaggatgatg ttagagggtg ggtttgaaaa ttttggtttg ggttttttta 10860 tagattttgg gtgaggtttg ttgtttatta gttaggtttt tttttgtatt tggtgtttat 10920 agagtatggt ttttttaaat ttttgggttt tttttgttta gggaagtata tttgggatag 10980 taggtgtgaa ggattttttt tatttattta tgtagataag ttatttatgg ttgtttttat 11040 tagttatttt tgttggtttt tggttttttt ttttttagtt ttggtttagg gtgagttata 11100 ggtgtttggt agggggtgta tagggagttg aggatagagg gtttgtgagg ttatgaagag 11160 tttatttgtt agggtatatg tagttttttg tttttgttga tttttagggg tgatgttagg 11220 tgtggataga gttggtggga ggaaagggtt tttattaata ttaatagtag ttttgtttag 11280 ttttggaagg ggttagtatt gatttttgtg ttttttgttt aagaatgtat taaatttttt 11340 aaggggtttt atgaggtagg gtttggatga gaaggttagt tattgttatg ggtgtttggt 11400 tgggggtttt tattttattt gttagagttt ggtttgagaa ggtaggatat agattattag 11460 gttttagaat agtttagggt ttgtttgatt tttagttttt taagatgtag ttgaaggatg 11520 ggggttgggt aggatatttg tataggggtt agtgtgaggt tttggaggtg tagatatggt 11580 atatttttaa ttttatagtt ggtggttatg gtttttgatt tagttttttt gtatttagta 11640 gtagggtaga tagtattgtt ttgtagtttt aggggataga gggaatttag ggtatttggt 11700 atgaggatgt tgatattgta gggatgtatg agtggttggt ggtggggatg aagtagaggt 11760 agtagtggat gtgggtgttt gggatgtgtt ttttgtggtt gatgttgatt tttttttgta 11820 ggtatttttt gtattggtta ttgatgaatt ttatgatggg ttgttagttg tgtgggggat 11880 ggggatgagt tagtaggtat atgagatgtt ttttttaagt aggttgtgta tttttaggat 11940 ttagagttta atattttatt ttttaatgaa atgtatgttt tgggaggttt ggtttgttga 12000 gtggagatgt tatagtttta tttttggttt tttaaattag tttttttggg ttggttttag 12060 gtgatgagtt ggggatagta agatttttta ggtaattttg ttttggttta gaatttttag 12120 gtttttgaga tgtgtggttt tggtagtatg ttaggtttta ggaggtgggt tttgtatttt 12180 tgtgggttgg gaaattttta gggttgattt tgggtggggt ttagggagtt ttgaagtttt 12240 tgttagtgtt tttttttttg gaggggtttt attagttttt gttgttgatg tggtttttga 12300 attttggtgt gttaattatt gttagtttta tttggatgtt ttttttttta atatttgtat 12360 agagttatgg atgtagagtt agaggggaga tggaagattt ttatagatat tttatatttg 12420 attgattttg gggtaatttt aggtaggtag tgatgataat taaggagata ttgggaaatt 12480 aatggttttt tttagttaat tttggtatag gttggtgatg gtttttttgg gagttttttg 12540 tttgttagat ttttggtgga aaatttagtt gtttgtgggg agtttagtgt gatggggttt 12600 ataggggttt gggatattga tttattatag ttagagtttt aatatgttta atatgttggg 12660 gatggtgggt atagtgagtt tttgttttgg ggatttggga ttgtttgatt tgggtatttt 12720 tatattgtat tagtgtttta ggaaggtatg ggtattttat atttttagtt tatttttagt 12780 tattgattgt gtgtgatggt tttgattttt aatttttgtg ttttaggaag gtaggggtgt 12840 tttgtatttt tagtttattt ttggttattg attgtgtgtg atggttttga ttttttattt 12900 tgtgttttag gaaggtagag gagttttgta tttttagttt gtttttggtt attgattgtg 12960 tgtgatggtt ttgattttta atttttgtgt tttaggaagg taggggtgtt ttgtattttt 13020 agtttatttt tggttattga ttgtgtgtga tggatttgat tttgatggtt ttggggatgt 13080 gtttttttga ggtgggttgt attgattttt ggttgatttt ggatttgaag agggtgttga 13140 ttaaggtgga tttatttaag ttgttttgtt ttggggagag gatgggaggt tggttagggg 13200 tttttttgga gagattagta gggtttgtat atggggtttt ttttatttag gtatgaggtt 13260 ttttagtttg agatttagta gtgtttgggt tattttttgg taatattttt gttaagtagt 13320 ttttgaggat tttatttttg agttgggtgt ttagtgattg tgtaaattta tatagttggg 13380 ttttgatgtt agtataattt aggttatagt ttttttttga gaggtgagtt gggtttggga 13440 gagttggtat tttttgtgtt ttttgtgttt tttggatagg aggttttttg gtggtttaga 13500 ttttggatag gatagaggtt gggttggtgg aggagtttag ggttgtttag ggtgtattag 13560 gtggttggga tttttgtagt ttattagggt ggttgtaatt aaagtttagg tgtttaaatt 13620 gttttttttt gattggttag ggtttgggta agttatttga ttttattgtg ttttagtttt 13680 ttgatttgta aaatgggata aatagttttt tttttgtgga gttggtgtga gtattaggta 13740 ggtttatgta tgttttatgg ggtttgtggg gttatgtgtt agggggtgtt ggtttgtagg 13800 gtggtgttat ttgagggata gtgattgtgt gtgtagatag ttagtttata ggtgattgag 13860 ataaatgagg atgaggaagt agtatttata tgtaatataa tatatataat ttatatatat 13920 tttatatata tattttataa tatatatatt ttatatgtat aatttataat atatatataa 13980 tttattttaa atatattttt tatatatatt ttatatataa tttttataat atatataaat 14040 aaattatata taatatgtgt gtgtgtgtgt gtatatatat atatatatat atatatatat 14100 atatattttt ttagatttgg agttttattg ttttattttg tatagagttg ttttgggtta 14160 tgttagtaat atattaaaaa aaatatttta ggttaggtgt ggtggtttat gtttgtagtt 14220 ttagtatttt gggaggttga ggtaggagga ttgtttgagt ttaggagttt aagattagtt 14280 tgggtaatat agagagattt tgtttttata ttaaaatgta aatattggtt aggtgtagtg 14340 gtgagtattt atagttttag ttatgtagga ggttgaagta ggagaattgt ttaagtttag 14400 gagtgtgagg ttgtagtgag ttaggattat tgttatttta gagtgataga gattttgttt 14460 tttaaaaaaa taaaaattgg ttaggtgaga tggtttatgt ttgtaatttt agtattttgg 14520 gaggttgagg agggtggatt atttgaggtt aggagtttga gattagtttg gttaatatgg 14580 tgaaattttg tttttattaa aaaatataaa aattagttag gtatggtggt atatgtttga 14640 ggtatgagaa ttatttgaat ttaggatgtg gaggttgtag tgagttaaga ttatgttatt 14700 gtattttagt ttgggtaata atgagatttt gttttaaaaa aatataatat aaaaaatatt 14760 ttaaattata ttgatgtttt gattttgata atattttttt aggaaaagtg tgggtttttg 14820 ggaggataga ggttggtgtt gggaattttt ggtttgaatt gtttagtagt ttaaggatgg 14880 atattttttg tttatttttt tttgtttatt aggtttgtgt tttggttaat tttaggttag 14940 gagttatgtt aatgttttag ttatgatatt ttagatttag gagatgttaa ttgggatatt 15000 gtaaggtgta tttttttatt attgttattt ttattattat tattattatt attattattt 15060 ttattattat tattattttt attagtatta ttattataat attattattg ttattattat 15120 tattttatta tttttgttat tattattatt tttgttattt ttattattat tattattgtt 15180 attataatta ttagtattag tattattatt aattatatta ttattattat tttattatta 15240 ttattattaa tattattatt atttttatta ttattattat tattattaat attattattt 15300 ttattaatat tattattatt tatattatta ttataattat tattattata attattatta 15360 ttattttttt tattattatt ataattatta ttattattat tattattata attattatta 15420 tttatattat tattattatt tttattataa ttattattat tatttatatt attattatta 15480 tttatattat tataattatt attattattt ttttattatt attattatta ttattattat 15540 aattattatt attatttttt ttattattat tataattatt attattattt tttttattat 15600 tattataatt attattatta ttttttttat tattataatt attagtatta tttttattat 15660 tattattata attattatta ttattattat tattattatt attattataa ttataattat 15720 tataattatt attatttata ttattattat tataattatt attgttatta ttattataat 15780 tattattatt atttatatta ttattattat aattattatt attatttata ttattattat 15840 tataattatt attattatta ttataattat tattattatt tatattatta ttattataat 15900 tattattatt atttatatta ttattattat aattattatt attattttta ttataattat 15960 tattattatt tttattatta ttattattat tattattata attattatta ttataattat 16020 tattattata attattatta ttattattat tattattatt attattataa ttattattat 16080 tattattatt ataattatta ttattattat tattattatt attattatta taattattat 16140 tattattatt attattatta ttattattta tattattatt attattttat tattgttatt 16200 attattatta ttattatttt tattattttt atgattatta ttattattat ttttattatt 16260 attattatta ttattataat tattattatt tatattatta ttattatttt attattatta 16320 ttattattat tattattatt tttattattt ttattagtat tattatttta ttattattat 16380 tgttattatt atttttatta tttttattat tataattatt attattattg ttgtaaattt 16440 ttgaataatt ataatttgtt ggggattttg tttggggttt agtttgtttg attttatttt 16500 atgggatgat tttattttat ggatgaggaa gttaaggttt atagaggagg agtttagggg 16560 aagatatata agttttattt tgttgagtta ggataaagtt gggatttttt ttggggtttg 16620 tggattttta aataggtgtt tttttatttt gtttgtattt ttgtaggtgg gtatagttgt 16680 tatgggaggg aggagggagg agagtagagt tgttttatgt tttgtttttt atttggtatt 16740 tttgggaggg agtgattttg tggggaatta ggattattgt tttttttagg gttgaaaggg 16800 tgaagaggtt tagataggtg aagtggtttt ttgtgtatta tttttagagg gtaaggttgt 16860 tatagtggta gttatggaag gtgagggttg ttgggttgtt tttttttttt tttggggtta 16920 aagttttgga agaaggtttg tgttatggtt gggatgtaga ggtttttagg ttttttttat 16980 tttgtttttg gttagggagt agggtagttt ttttgtagtt tatagagatg agttttagtt 17040 tggttattgt ttttgggttt tttttttttt ttttttttta gttatttttt tgggaggtag 17100 ttttgaattt ttagggtata agtatgtttt ttataatagg tagaataggg tgggggttgt 17160 aggaggggat tttatatttt tgtttttttt tgaagtaggt tgttagtttt taggtagttg 17220 tgagtatagt agggttatga gtagttgggt tttatgaggt tataggaagt agagaggata 17280 ttaagatttt aggggagtta gggtttagat tagtgtagaa gaggaaagaa aggtgttggg 17340 ttggtaggtg tgggtttgtg tttatagagt tgggtaggaa ggatgtgtat ggttggtaaa 17400 ggttagagaa ataggtttgg tttgagaggt gtttagatat tttgtagaaa ttttgtaagt 17460 ttatttttgt ttagggtgtg atttggtggg ggtatttttt tagatttttt tttggatttt 17520 gtggagtggg tagaatatag ttttgggagt taaaatggtg gttgtggttt tttgttttgt 17580 gagttaagga attttggtag ttttttttga gttttgtttt tgtttggaaa atgggatgtt 17640 ttttttatag ggtttttgtg aggtttgaat gggatttggg gggttttgga aataataggt 17700 ggtttattgt agattttagt ttggtttttt tattttgttt aggttgtgtt gattgatgat 17760 tttttgtggt gatttttagt tttttggggt tattaggggg tgtggaagtt atgaggtttt 17820 aattttaggg tagagttgaa gttgagttgt tgggaagttt ttggttgggg tgtggtgggg 17880 tgtggtgggg agtttggagg gttaggttgg agtaatagtg aggggatagt tgttatagaa 17940 ttttttgtat aagttgatgt tattgtttag aggtagtgat tatttattag gatttgtttt 18000 aggttggttt gggtttttta aagttatttt aggggttttg gatgtgtagg ataggttttt 18060 ttgaggagtt gttggaggtt gtgggttttt tttaggtgta tgtatgtata tgtaatgtta 18120 ttggtaattt gtttttgagg ttagggttgt tgttttattt tatagaaggg aagattaagt 18180 ttaaaggttt gtgggttgtt ttgggggttg aggttggttt ttggtattgg ttgagtggta 18240 tgtaaggtga ggatttattg attattatga tgttgaattt gaagttttgt tttatggttt 18300 tttggtgtat ttgttttagg atggagttaa tttttatgta gttgaagttt attggggttt 18360 ttttgttttg tgatgtaggt gtttgtttga gtttggtatt tttgggggtg ttggttatgt 18420 tgttaatgta gttgggagtt gttttagtgg ttggggaagg aatagtagag gagttagagt 18480 ggaatagggg tttatatata ggtgtttgtt aggtggttgt tatatttatt tttggatggg 18540 gaaattgagg tattgaggtt tagaaaggtt aagtgatttg tttaggtgat ttttgagaat 18600 ttttttgggt ggatgttttt ggttgtggtg ttttttaaaa agttgttatt ttgtagttat 18660 gttgtttttt tagtaaagtt ttatttttag atttttaagg ttaggttttt ttattttttt 18720 ttttaggagt tgtgttaagt tgggggtttt ttgtgtttta aggtagggtt gattttgaat 18780 ttttgttttt gtattttgga gggttgttta gataagggtg gagggtgttt tttttttttg 18840 gttttttata ttgttttggg ttatttaggt ggatttggtt ttttttttta tttttattta 18900 gataagttgt attgtttgtt gttatttaaa ggttttagaa gttgatttat gagttaagat 18960 ataggaggga tggttttgta agaaatgggg atagaattag tgtgtgtttt tgttttttat 19020 atttttatgg atggttttgt aagaaagggg gatagaatta gtgttggttt ttatggagtt 19080 gtgtgtttaa ttttatagaa tgagttagta gttttgggag aaggaaaagt gttgggtgta 19140 gggtgggtgt ttggatgtag agttgttttt gggtttatgg aggagggggg tttttgtatt 19200 atatttgttt ttttttggat tgatttaggt ggttgttttg tgtgtttggt tagtgtttat 19260 gggttgtata tttataggtt aagattaagt tttatttttg ggtatgtggg gtatgtggag 19320 ttgaattttt tgaaattatt aaagtttttt ttgtttgtag gtttttttga tggttttgtt 19380 tttggttgtt gttaagatat tatatatggg ttagaggttt ggggttgggg gtggatgttt 19440 ggaagatgtt tgttgaggat ttaggtgttt ttatatagtg gggttttagg ggtatttagg 19500 atggggttgg tttttattag ggttggttgg tatatgggtt aggttttagt atattttaga 19560 tttgttatat ttattggtgt atgtgtatgt aggtgtagat aatttgttgg ttatagaggt 19620 ggtgtttttg ttagttttta taggttggag ttgtttttgg tggtttttag tttttatgta 19680 ggttgggtgg ttgttgtttt gtgtttttgt ttttgtttgg gtttatttag gttttgtttt 19740 gtttgtgggg agatttttgt tttattttgt tttttaggga ggatttggtt ttaggtattt 19800 tgtgttaaga tagggattat atggtatgtt tttaggtagg gttttttttg ttagtttttt 19860 gggaggggag tggttttttt ttgggattgg tgggtattta gtaggggtag ttatagggga 19920 gtggagttgg tgtgggagtt agggttatag tatgggaggt tgtagggggt ttattttttg 19980 tgataggtaa gtgagtagtt tttttagata ggaggtagtt tttttggttt atgtttattt 20040 tttattttgt ttagaaggtg ggaggtaggt ttttaggtta ggaggggtag tgggagattt 20100 tagtttaatt gtttttttat ttgtggggta agaattgaat ttaggaaatg tttattgagt 20160 tttttggttg tagtttgtat ttttagttga tttaagttat tttttttggt ttattttatt 20220 ggagtggtta gagggtgttg gagggaggtt ttttaggttt gaggtattag aggtgagaga 20280 ggaaaagatt ttggaagtta gaaattgggg gttggtttat ttttataggt atttttttgt 20340 ttttttagtt tttatagggt ataggaattt ttattttatg gaattggggg aataaaggaa 20400 taatataatt ttttgttggg aaatgttaag ggggggttta tatattttta ttgttgagag 20460 taatatttat aggtggattt ggaggttagg gttttttttt ttgtgttttt atgtggtttt 20520 tatttaggtt atgtagtttg gaagttttta gggttttgtt tttgtttttg tttttttttt 20580 agaaatattt ttttttgggt ttttaggatt tttaaataaa taaagatata gttttgtatt 20640 tggttatgga ttatgtggtt ttggggttgt tttttgaagt tagatatggg gttttgtttt 20700 gtggggtagt agtttagttt ttatttatgt gattgaaaat tgtttttatt tgtttgtggg 20760 tttgagagtt attttgtttg ggattgggat tagtttttat ttgtttttat ttttttttag 20820 tattttttaa ttttttttag taggatttgg ggggaggtgt tgttttttga attttttttt 20880 tttgttttta atgtttttgg agtttagagt gagggagggg ttggtttagt tgtagttggg 20940 tttttttata ggtattagta tttattgtag aaatttaaat taaattaaat attttgttta 21000 ttaggggttt tgtttgagaa ataataatat aatgtagttg agttttattt ttgttattga 21060 tgtagggtag tggtttgttt tttgtatagg tgagagttat ttttgtaatt ttttttttga 21120 gaggtggttt tgtaggtttt ggttggtttg taggtaggta tgtatgtaga gagtaatgta 21180 agagtttgtt ttgttttttt atttggttag gtgagttttg gggtttgttt ttaggatttt 21240 taagtgggaa aagtagagat ttttatattt agagatattt ttattttggt tttaggatat 21300 tatggtgttt agatagttgg aaataatggt aaagattatt tattttattg tttgtgatta 21360 tgatattgtt tgaggtttgt gttgtttagt gtggtagtta ttggttatgt gatttttttt 21420 tttaattgtt ataatgtttg ttatggttat tattttgaag tgtgtagttt agtggtgtta 21480 agtatatttg tattgttgtg taataaattt ttagaatttt tttattttgt aaaataaatt 21540 gtttttatta aataattttt tagttttatt ttttaagttt ttggtaattt ttattttgtt 21600 gtttttttga atttgattat tttatggatt tggtataagt ggaattttat aggattgttt 21660 ttttgtgatt aaattatttt atttagtgta atatttgaaa ggtttatttt tgttgttgta 21720 ggtattttaa tttttttttt atggttgagt taaatttttt gtatgtttta tttttttttt 21780 tttttttttt agatagagtt ttgtttttgt tgtttaggtt ggagtgtaat ggtgtgattt 21840 tggtttattg aaatttttgt ttttttaggt ttaagtaatt tttttgtttt agttttttaa 21900 gtagttggga ttataggtat ttgttattat gtttggttaa ttttgtttta gtagagatgg 21960 ggttttttta tgttggttag gttggttttg aatttgtgat tttagatgat ttatttgttt 22020 tggtttttta aagtgttgag attataggtg tgagttatta tgtttggttt gttttgtttt 22080 tgattttttt atttatttga ttgtgggtat ttgggttgtt tttatttgtt ggttattgtg 22140 aatagagttg ttatgaatgt gggtgtataa atatttttag ttttttaaga tgttgtgtat 22200 ttttttgaat ttatatttag aagtggaatt atgggatgtt atggtggttt tagtttttgt 22260 tttttgagga attgttatag tgtgtttata agtgattttt gagtatttga tattgagtta 22320 gtttaattga ggaatggaat ttttattttt atttaaattt aaatagttat attttataaa 22380 tggtaattat attggatggt atagaatttt agtttaattt attttttatt aatggggaaa 22440 ttgaggttta tagagtgatt tttttttttg aaatgttatt gtaagtggtt aggttagtat 22500 aagattttta ttgaatttgg taattttgaa attttatatt tttgtttgta tgatatgtgg 22560 ttaatatttg tgattttttt taaagattgt gggttttagt aagatggtag ttgttttgtt 22620 gagattttta ttgtattttt aggttttgtt ttgttatgaa tatggttgtg taaggatttg 22680 tttgggtttt tgttttttat ttttttgggt atttagatta attattagta gtatttatgt 22740 tgatttttag aaaggttttg atttggatag taattgatat gttattttat agttaaagta 22800 aaatgtagag tttttttttt ggttttgtag ttgggagtta gaggttttag gttttggttt 22860 ttggtttaaa gtgatttttt gtaagttttt ttagtttggt aaataggtta tgtatttttt 22920 gatttttttt ttagtttttg ttttgtgagt ttttgggtgt ttgaggttgt ggtttattta 22980 gtgatatttt tagtttttag tgtagtttgt gagtagtata atatatttgg ttttagaaat 23040 aattaatata tttgttaata gatgtgtgga gaaatttaat gtgttgagtt aatatagtgg 23100 attatttttt agttataaaa aggtatgagt gtgtgttaat atagatgaat tttgaaaata 23160 ttttaattgt aagaaattaa gtataaaaag ttatattttt tagggtttta gttatatgtt 23220 tagaataagt atatttgtag ggataaagtg tagattggtg atttttaggg gttgggggag 23280 ggggagtgat tgtgtattga ggatggtgtt tttttttggg gtgaggaaaa tgttttggaa 23340 ttagaggtga tgtttataga aggttgtgaa aaaatgttat ttaattgtgt tttttgaatt 23400 ggtggatggt gtaatatgga aattatattt ttatgaggat gggagaggaa gggaaagaag 23460 ggaaggaggg agggggaagg aaatagggaa ggaaggaaaa aagggagggg aggagggagg 23520 gatggaagaa gggaaagaag gtagttattt ttagtggagt tggattgaag agtttaatgg 23580 gtgtagtaaa ttattatggt atttgtattt ttatgtaata aatttgtatg ttttgtatat 23640 gtattttaga atgtaaagta aaataaaata aagagtttag tgttttttat aagtgtttag 23700 gagttagttt tatagtttag aggatagttg aggtttagag gttaatattt aggtttgagg 23760 tttttaagtt ggtgttgtta gattatgttt tagataaatt tttttatttt tttgtagtaa 23820 gggtgttttt agggtggtag ttaggtggag gtgttaggtg gtgggagatt ttgatagttt 23880 ttttgtaggt ttttattttg aatttaggtt ttatgttagg gtttttttgt tatttattgg 23940 tgttggtggt agtaggttat tggttttgtg atggggattg tttttaaatt tgtttatttt 24000 ggggattagt tttttttttt ttgtaggtgt ttattgggtt attttttttt tagagttgta 24060 ggtgggttta aggtagggat gaaagggttg taatttatgt agttttgagt tagtattttt 24120 tgggaatatt tgtatttagt gataaatttt tattttaatt ttaggatttg ttgaggatga 24180 gggaattaga ttgttgtttg tggttgggat gggggttgta ggatatttgg ttgggaggta 24240 gtgtttagag aggaggtagt tattggatat gatatatttt aggggtattt atatttatta 24300 tagttttagg gttgattttg gtttatttgg tttggtgttg agagagggtt tgatatagta 24360 ggtttgtaaa gtttgatttg gaaattaaga tttaggggtt gttttttttt gtttattttt 24420 ttttgtgtgt tatgttgttt ggtttatgtt ttagaaatgt ttatataagt tttattagtt 24480 ttgttggtta aatgtagaga tggtgttgtt ggggtaaggg attttgagtt attgtttaat 24540 gttattttta gttttagggg agtgatagtt gggtttgtat tttaggataa agtgtttagg 24600 gttaagttaa tgttattttt ttgttttttt taaatttaat ttatatttgg tttttagagt 24660 atggattgaa atggttatat ttttatatat tttgtttgtt attgttaatg gtggttaagt 24720 agaatgtaag gttatttttt ttttgtttat ggaggtttgt gaagttattg attaggttat 24780 ggtaggggag ttggtggtat ttattatatt ttgttagttt tttaggtttg tgtttaggag 24840 aaagttgttg gtatttatag ttggtgtttt tgttttggtg aagatttttt tgtttttatt 24900 tattttggtt tagtgtgggt ttagtagttt ttttattttg ttttgtaata atgtatattg 24960 gagtagtttt tagttgtttt ttttttgtag gtttttttga atttagattt tggggttagt 25020 atttttgtgg tagttttatg gttatttgta ggttttttta gaaatttgag tttatggggg 25080 tattttaggt tttataaatt aatagatgtt ttttgttttt tataaagggg ttttttaaag 25140 ttgagtgagt ttttgatgta ggtaatgtta ggaggatagt gtttggttag ggttgttttt 25200 tttttttttt ttattttttt gggtgtttgt aaagtttttt agatttttgt tgaattttgg 25260 ggaagttttg ttttgtaatt agggtttgtt ttttttgttt ttatatagag tttgtttttt 25320 gtgtttagat agttttttta tgatggtaat tgaataatga tgtgtgtggt ttttttttat 25380 tataattttt ttatataggg tttgtgaagt tagatatttt atttattatg tttattttag 25440 tttggttttt tttagagtag tgtagggttt atggtaagtt ttggtaaaaa gtttggtgaa 25500 tgaatgaata aatgaagaaa taaagtttat tatagtagtt gaggtttatt gggggttttt 25560 tgtgttaggt gttattttaa tttttttttt tagagagtgg gttttattaa tgttggttag 25620 gttggtttta aatttttggt tttaagtgat ttttttattt tggtttttta aagtgttggg 25680 attatagata taagttattg tattgagttt taggtgttat tttaaatgtt gtttaggagt 25740 tattataatt gatggattat tatataattt tataaggtag ttattgttat tgttttattt 25800 tatagataag gaaattgaga ttgagagggt ttttgttaat tatgagggtt gtaaagtgag 25860 taagtggtag agttaggatt tgaagttagg taggtgagtt ttaggttgtt gatttttttt 25920 ttaggttagg tttttgggaa ttatggaaag gttggagaag tatggggttt ttgtagttag 25980 gatttagaag gtgtagttgt ggtgtaggta gtttagtatt gaggttttgg tttttagttt 26040 tttttttagt tgtttttttt tagggagttg gaggtagagt tttgaattgt taggagaaga 26100 ttttatttgt tagttaggga aagttgttag ggtttttttt agggtttaga gttattttag 26160 gtttattaaa gtatattagt attttagttt ttataatttt ttttgtaaga aagatgatgg 26220 tattagttat tgggttgggt tgggggtttt agattttagg ggttttttta ggtttgttta 26280 tggttttttt aggatataga tgtttatttg agaaatttta gtgtattagg ggttttatag 26340 ttaaaataaa gaggtagagt tgttttgggg tttttgttaa agtttttagg tagatttatt 26400 tagtagatat taaaatgttt attttttatt tgaaaatttt atttttagga ggttgtttta 26460 ggttgggttg ataaaattta tagagatttt aatgatgatt ttttatttta ggtatgagtg 26520 agtgggtgga gggagaagtt attgttaatt attaatagtt taggaaatgt aggtaaagga 26580 aagagaatgg taaggtgata gggttggaaa ttagatatat gtgtagaggt gagtagattt 26640 tagagaaaga attgttttgg aataagatgg taaagaaatt atagataata atggtagatg 26700 atgattttgg ggttttagtg gattaggatt ataatattga tttatttgat aagtatttat 26760 tgagtgttta ttttatagta ataaaaagat gatattatag gtttgagagt agttagaatg 26820 aaaatagtgg tggtatatgg gaatttgaag tttatttatt taaatgttta ttagttgaga 26880 tttttggata gatttgaagt agtttttaat atgtaaggaa tttataattt gatatagtag 26940 tataggatat gtgtgtgtta taaatttttg gtgaaaagta aagatttttt ttagaaaagt 27000 atatattgaa gatagataga tagatatata tgtattttga atggtttatt aaagaatttt 27060 taggtttgtg gattttagtt aaaaaaataa tttggtattt tgggaggttg aggtgggagg 27120 attgtttgag tttaggagtt taagattagt ttgggtaatg tagtgagatt ttatttttat 27180 aaaatgaaat aaaataaaat gagaattaaa aaaaataaat aaatttggtg tgatgagaat 27240 ttatagaatt taatagggtt attttagtat tatttgtagt attttttaaa tttttgatta 27300 tatatataaa gttttgggtt ttatagttag agaagaggga gagtaggtta aaaataatta 27360 tttaaggtgg aagatgagtt tgagaaataa agaggtaaga ggagaagatt gaggttagtt 27420 gttttttatt tttgagtttt ggtaggagga agtttttaag tgagaataag ttgttgtttg 27480 tggagtggat tttagagtgg gtggatagag atgataagga atgttatttt tggggggttt 27540 tgaaaatagg atattttttt attttaattt tgttttttat tgtattgtgt ttttattgat 27600 ttatttaagt tattataaat attttataaa tgttattggg gattttttgt ttttttttaa 27660 agatggaaat attgaatata aatgattaaa ttgtgtaaat gtgtgtgggt gggggattaa 27720 ggattgaatt tttaaaatgt atatagttta tttaatttgt taattaattt taaattaaat 27780 tatattttat attttgtatg ggataggaag tgttttttta aagtttggtt aggatttggg 27840 atgttggaaa tttgagattt tgtttttttt ttttgagata ttttgaaatt ttgtttagaa 27900 attgagtata atggttttgg ttttttagag aaagatatgg atttgtaaag gtaaagagtt 27960 gtattttttt ttgagttgga gttttttttg gtttttatta tggggtttaa ataaaattgt 28020 agttttatag tttttttgtt ggtgtttttt tttttttggt gattaataag gtggaagagt 28080 taataagaat tttgtgtgtt tttttgtagg atttggaagg gataggtggt gtgagtttgt 28140 ttttatttag tttttttttt tatttattta ggggttgagg tgtttttgag gtagggggtg 28200 ggggttttta tttttattgt tggttaaggt ttttttagtt ttttttttgt taaatttttt 28260 taagtaaatt ttttttttat tgtggaggaa ggaattttaa gtagttttgt ttttttgtta 28320 gtatggtttt aattggtttt agttggtaaa gttaaatttg gataaggttt aagggttttt 28380 tatattattt gttgtttttt ggaagaggtt tttttttgtt tttttatttg taatttatta 28440 tttttttagt ttgagttttt ttatttaggt tttgtggttt attgagatat taattttggg 28500 ttagagtaag ttttgatttg taaattatta ttatttattt tttaaagagt tatttttaga 28560 atttaggttg tagggagggt aggttaagga tgaatttttt gatttttggt gtggtgtgtg 28620 gtgggggggg ttattttata ttttgttttt tgttgttttt ttgttttgtt ttaggttttg 28680 aagtggattt attgtagagg gagggttagg gaatggtttt gatgtttttt ttattttaag 28740 gaatttttta gtaggagtgg tttttatttt aaagtaattt taagatttag tttgtgttag 28800 ttttttagtt atgtttatag tggtttgtta attagagatt tttttagttt ttggtaaatt 28860 tgtaaattta taaagagaaa gaaaagtttt tttgtgggtg ggtggatatt ggttatttgt 28920 tataggttgg aatttttttt tattagggat gttttttaag taggggttgg ggagggtagg 28980 gtttagagtt tttttttttt tagttttttt tgttattagt agatttgtta gtagatatat 29040 agtagagttt agtagtgagg taataatagg ggttgtgggg gttggggttt tgtttttttt 29100 aatttatgaa attatttgaa ataataaaat ttagataagg gtttttgggg tgtaataggg 29160 tggttttttg ttaggtgttg ggtagaaaaa aagttttttt ttaatttttt tttgttgtgt 29220 agattagttt gggttttggg gatgttgtag aggttgtttt atgtttaggt tttttagaga 29280 tagtaggggg ttggaggtat ggtttgtttg ggggtagggg ataggtaggg aggggtatat 29340 ttttgggtta tgagtaggag tttgattaaa tgattttttt aggagggaga aagatattgt 29400 atataattgt ttgattatag ttagaggggt tggaaaggtg ggggaaaggg gtgaaggggt 29460 taattgtttt aggtgttttt aatttatgta gtatttattt ggattgataa gagttgagag 29520 attggaattg tttttttttt ttgtttttag gttttgtttt aggagttttt ttgtttagga 29580 gtttgggagt tgaggaggtt tggaagtagt gggtttatag tgttattgtt ttgggaattt 29640 atagtgtttt ggatgtggtt tttttggttt tagttttgta ggtagtttat ttggattgta 29700 tttatttttt agaagagttg tttagaattt tgtatgtttg aaagaaagat taattaaaga 29760 agtgaggaag ttaaagagag gtttatgaaa gtttatgatg tattttttaa gtgtatattt 29820 tagtaatttt aaatgttttt tgaagtaagg atggggatgg atggttggat aaatggatgg 29880 gtgtatgggt gtgtgaatgg gtgagtgggt gggtggatgg atggatagat ggatgaatgg 29940 atgggtaggt ggatgaatag gtaggtgaat ggatgggttg gtggatgaat gagtaaatgg 30000 atgaatgatt ggatggatgg gtggatgagt agataggtgg atgagtgaat tggtggatga 30060 gtggatagat ggatgagtgg atgagtagat gagtgaatgg gtggatgagt ggatgggtgg 30120 gtgagtggat gagtagataa gtggatgggt ggatgagtgg atgggtagat ggatgggtga 30180 gtggatgtgt ggatgagtgg atggatggat gagtggatgg atggataagt ggatgggtag 30240 atgagtggat ggatagatga gaggatgggt agatggatgg gtgagtggat gggtgggtga 30300 gtagatgggt ggataagtgg atggatagat gagtggatgg gtggatgagt ggatggatat 30360 atgggtggat agatgggtga gtggatggat gatgagtgga tgggtggatg agtggatggt 30420 tgagtggatg gataaatggg tgaatgagtg gatgggtaga tgagtggatg gatagatgag 30480 tgaatgagtg gatgggtgga tgagtggatg gatagatggg tgaatgagtg gatgggtgga 30540 tgagtgaatg agtgaatgag tggataggtg gatgagtgga tgggtggatg agtgtataga 30600 tagatgggtg gatgggtgga tgagtggatg ggtgggtgag tggatgggta ggtggatgag 30660 tggatggata gatgggtaaa tgagtggatg ggtggatgag tgaatgattg tagataggtg 30720 gatgagtgga tgggtgaatg agtggataga tgggttgata ggtggatgag tggatgggtg 30780 gatgggtggg tgtgtggatg ggtgagtgag tggatgggtg ggtgggtggt aagatgggtg 30840 gataggtata tggagtttat ttaaggagtt ttagaaatat atatatattt ttttatttta 30900 gatttttttt aggaaaaagt agtgtgtatg gattgttatt tggttatatt ttgagatagt 30960 tatttttatt ttttttggaa tattgtttgg ggggatgtag tatagggtat ttaagtaatt 31020 tttgagttta gggtagagat attaggaagt agtaggtagg ttgtgatttt gtaggtttgt 31080 tttatggttt ttgttgtttg tattatggta tgaagtttag atgtattttt ggatttgggg 31140 ttttgattag atggagttat taattttttg aagaatgaaa tatatagggg ttatttttgt 31200 tttttagttg tagggaatga tgattattta gttttttttt tttttaaatt ttttttaggt 31260 ttttgtgtat ggttttgttg attttttttt tgtttttggt tattttttta gtttttgttg 31320 tttttttttt tgtttttatt tatggagtta gttttggtgt tttgagagtt ttttttttta 31380 gttgatttta tttagttttt gagtatttaa tgttaataat gttatttttt ttgtttagat 31440 ttatatttga gtgttagttt gatttataga tgtgtttttg ggttttgttg tgttaggttt 31500 tttgttgggt tttgggtatt tgtagttatt gttattgtta agttttaata tttgaaggta 31560 ttttgaattt aatgattgtg ttttaggttg aattttggag tttttatttt atttgttttt 31620 tattttattt tttatttaag tgaatagttt ttttagttaa tagttattgt agttagattt 31680 ttaggggttg ggtttgggtt ttttattttt attattttga atttatttat ttattttaaa 31740 tttttattaa tgttaattta atatatttta tagttattat tattagttgt ttttgtttga 31800 attttttttt tttaaagtat tagggggtgt gtgtaaaatt tattaatttg atgatttttt 31860 tttatgaagt tgtgattggt ttttattgta tttgggatat attagatttt tgtggtttta 31920 gaattttgtt tattattgat gtgttgtgtg attttgagta agtaatttaa ttattttgtg 31980 ttttaatgtt tttatatgtg aaatgggata ataatatttg ttttataaga atgttgggga 32040 ttaaatgaga tatttattta tgaagtatat agtgttgtgt ttggttagta aatgtttgaa 32100 gtttttgtta ataaaatata tgtttttaat ttatttttta gtttttattt atgtatagtt 32160 tttttggttg ttttttagtt tttttaataa ggttatttat agaggttttt tttgttggga 32220 ttattttttt tttatgttgt ttttagaatt tttatttgtt tttttgggat agtttattta 32280 tattgggttt tttagttttt gttttgtttt gttttgtttt gttttttttg agatggagtt 32340 ttattttgtt gtttaggttg gagtgtagtg gtattatttg ggtttattgt aagttttgtt 32400 ttttgggttt atgttatttt tttgttttag ttttttgagt agttgggatt ataggtgttt 32460 gttattatgt ttggttaatt ttttatattt ttagtagaaa tggggtttta ttgtgttagt 32520 taggatggtt ttgatttttt gattttgtaa tttgtttgtt tttgtttttt aaagtgttga 32580 gattataggt ttgagatatt atgtttagtt taggtttttt agtttttata tatgtggttt 32640 tttgattgtt gtttggggtt tgttgtattt attatttata aaattttata tgtttgaagt 32700 atttagtaag atgttgtgaa tgagtgaatg aataaatgaa tgaatggtta gtttgttgtt 32760 tttttgtttg gttttttgtt ttttttagat tagtatgggg gtagttatgg tttttgttta 32820 ttttggtaat attgtttttt ttgtgttggt tgtgttggtt agagtttttt tttatggtgt 32880 ttttgtggtt ttggtgtgtg gttgtttgtg aatgagattt atgatttttg gtttttatta 32940 tttttttgga gttataaagt attaaggtgg aaggatggat gggttttttg ggatagttgg 33000 ggtgggaggt tggtttagga aatttttttt aggaaatggt tagtgtggga tgaggtgttt 33060 ggtgggaggg gagtggagtg gggatttggg gtttggttgt tttgtagtta gggattttaa 33120 tttttatttt tttttttgtt tattttttaa ttttagtgtt gggtttaggg tttttggggt 33180 tttttttagg aatatagaag atatagtaag gattagggat ataggatagg tagagtttat 33240 gggtaggagg tttttagtta gtatatttga gtttatgttt ggttttaatt agatattgag 33300 attttggtta ggttattttt tatgttgagg taggggggtt ttttagaggt tattggtttt 33360 taagtattgt gtggaagata tgttatggag agttagtatt ttttgagata ttagtagaag 33420 gttagatgtt ttgtggttta aggatgattt ggttttagtg tttatttatt tgttgttttg 33480 tatgaaaagt ttgatgtgat atggttggtt ttagtggaag agtgatttgg gaattggtag 33540 agtggattta gtaattggta aattggattt agtaattgag atattgttag gggtttggta 33600 gaagtttttt aatgtattag atttagtttt gatttttata gagtttagtt gagtattaaa 33660 aggtgtagag gttgagttga gtattagggg aatattgatt ttagggttga ttggtgttgt 33720 gtgtgtattt tatagtttat agatggttta tatttatttg attgtatttg attttttttt 33780 gtgaggtttt ttttagattt tttgtttttt aaagttatta gttgtgtttt ttgaaattag 33840 agtaaagtaa taaaattgta gtaatagtgt gtttttatga atgttgtgat gttagttggt 33900 taaatgaggg agtttttagg gttttttata ttgttttgat tttgtgtgtt ttttggtttt 33960 ggtttatttt ttatattttt tgtttttttt tttttttttt tttttgagga tttagggttt 34020 ggggttgatt tattgtggga ttttaatggt gattttttgg aagaaatgtt tgtttttttt 34080 ttttatttag tagtgatttt tggtttgttt atgtttatgt agttaatata ggtagtagtt 34140 ggaatttgga agtttttggg gtgggagttt gttttttttt aggttttttt agtttgaatt 34200 ttgggaagga gttatattta tatggtaatt ttttttaagg ttgggagggg gaaggggttt 34260 ggtttgggtt tgattatttt tttgaggttg tgtttattgg gttttttaag ttagttgggt 34320 tttttggttg tatttttgag ggatggtaat agattatagt gtaaattgtt tattggttgg 34380 ttgggtagtg ggtgtttaga tgtgggttag ggtttttgtt ttataggttg tgtggtggtt 34440 taaagtgggt atttttatgg gtatatattt gtgttatagt ttatttgtgt gtgtgtgtgt 34500 gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtgtgtgtga tagtttagaa atatggtaat 34560 ttatagtttt tttaagatgt tggttttggg agatttgttt atttgggggt tttagtattt 34620 ttagtttttt ttaggaaggt tttgtttttt ttggtttgaa gttggtttta gggaagaatt 34680 tttttagaaa aataaaagtt atttttttta gttttagttt agtttttttt taggggtgag 34740 ttatattaaa tttatttttt tttttttttt ttattttttt ttttatgttg taattagttg 34800 taagtggttt atttatttag gtttgttagt ttattataga aaagatattt gaattttgta 34860 tttttttttt ttgatttgtt ttgggtttta ataggtaaag gaaattggaa gttagtagtt 34920 aggatttagt tgtaggtttt tggggttatt ttgtgttttt attttagttt tatttatttt 34980 tgtgttgatt taatgtttat ttattttagt ttatggagtg aggtttggat ttaagataaa 35040 ataaaggggg ttttggtttt ttggggttta tagtgtttgg tgttggtgag ataattttag 35100 agtatagtat agagaaatgg ttgtgatatg gatttgtagt atttggttgg ttaagtatag 35160 taatgtattt ttattaggtt tgggtttttt agtagatata tggtttaaag gttggttggt 35220 taaattatat gattttgtaa ttatttaaga gaaatgaaaa tatgtttata taaaaatttg 35280 tagattagta tttattgtag aattttttat aatagaatta tgttaaaaag tagaaataat 35340 ttaaatgttt attagtagat gaagagatat atagtgtggt ttatttatga tggaatatta 35400 tttggttatg aaaaagaatg aagtattagt atttgttata atgtggatga gttttgaaaa 35460 tattttatta agtgaaagga gttagatatt aaggttatat attgtatgat tttatttata 35520 taaattattt agaataggtg aatttataga gatgaaggta gatgagtggt ggttaggggt 35580 tgagagtttg gagttgggaa tggggattgg ttaatggggg tagggttttt tttggggatg 35640 atgaaatgtg ttgggattaa tggtgatggt tgtgtaattg tgatggttaa ttttttgtgt 35700 tagttgggtg tagtggttta tgtttgtaat tttagtattt tgggaggttg aggtgggtgg 35760 attatgaggt taggagattg agattatggt gaaattttat ttttattaaa aatataaaaa 35820 aaaaaattag ttgggtgtgg tggtgggtat ttgtagtttt agttatttgg gaggttgagg 35880 taggagaatg gtgtgaattt gggaggtgaa gtttgtagtg agttaagatt gtgttattgt 35940 attttagttt gggtgataga gtgagatttt gttttaaaaa aaaaaaaaaa aatttttgtg 36000 ttaattggat tgggttatgg ggtatttagg taattggtta aatattattt tgagtgtgtt 36060 tgtgaaggtg tttttggatg agtttaatat ttaatttttt tattttttag aaagtttagt 36120 ttattgttag tatttattta attttatata aatatgtttt ttgaggttga agtaaatttg 36180 attggatgtt ttgtgtgaaa attaaatata aaaattggtt aggtgtggtg gtttatgttt 36240 gtaattttag tgttttggga agttgatatg ggttaattat ttgaggttag gggtttgaga 36300 ttagtttggt taatttggtg aaatattgtt tttattaaaa atataaaaaa ttagttatgt 36360 gtggtggtag gtattttgta attttagtta aatttaggag gttaagattg gagaattatt 36420 tgaatttagg aggtagaggt tgtagtaagt tgagattgtg ttattgtatt ttagtttggg 36480 taatagagag agtttgtttt aaaaaataaa aaaattaaaa agaaaaaaaa ttttttaaat 36540 tgtttttgta gttattttta agtaaaataa tagagttatt tgagttgttt attttggaaa 36600 aattagattt attaaatgaa tttttagtta ataattgatt aagaataatg ttaatattat 36660 ttgtaggaat gttgtgtttt ttaggatttg atatttttag tgattgagaa ttattatttt 36720 tttttaaatt ttatttattt atttattttt tgagatggaa ttttgttttg ttgtttaggt 36780 tggaatgtaa tggtgtgatt ttggtttatt gtaatttttg ttttttgggt ttaagtaatt 36840 ttttggtttt ggttttttaa gtagttggga ttataggtgt ttattattat gtttggttaa 36900 tttttgtatt tttagtagag atgggatttt attatgttgg ttaggttggt ttttaatttt 36960 tggttttagg tgattagttt gttttagttt ttttaagtgt taggattata ggtatgagtt 37020 attatattta gttgagaatt attatttttt tttaaaggaa atattattat taaaaatgga 37080 atgttataaa tagaatgatg ttttttgttt ttaaagttga tatattagag tgatgtgaaa 37140 ataataataa aagtaagata ttttttggta aatttatttt ggggtgaatg ttgtagttat 37200 aagtattgtt ggtgagtatt tttggggtaa ataggaaaag ggtgtaatta ggagtttggg 37260 taaagtagat tgtgtgtttt gatgggggtg ggttttattt gattagttga aggtaatagg 37320 gtttggaatg tatattttaa gatatagtgt tttggtatag taaatatttt tagttgaagg 37380 aatttaagaa atggtaggtt taagaagaat ttattgattt gttttttttt tgaagtagat 37440 tataagtttt ttatgtaaga ggtgtttttt ttatatttag tggaaaggaa tagttttatt 37500 tttagagata gaggatttga gaggggtttt agtatatagg ttttgttgag atttttatgg 37560 gtttattgtt tagtttattt tttgttgttt tgttatagtt ttttatgatt ttttattttt 37620 tattaaattt agtataaaaa tgtttaggtt taggttaggt atagtagttt atatttataa 37680 ttttagtatt ttggaaggtt aaggtggtta gattatttga ggttaggagt tgaagaatag 37740 tttggttaat atggtaaaat tttattttta ttaaaaatat aaaaattagt tgggtgtggt 37800 ggtatatgtt tgtagttgta gttatttggg aggttgaggt atgagaatgg tttgaattta 37860 ggagatagag gttgtagtga gtagagatta tgttattgta ttttagtttg ggtaaaagat 37920 aagtaaaaga aataaataaa aaaattgttt aaaataagta ataaataaat ttaaaaaata 37980 agtaaaataa ataaaaattg tttaggttta ggttgggtat agtggtttat atttgtaatt 38040 ttagtatttt gggaggttaa ggtaggagga ttgtttgagt ttaggagttt gagattagtt 38100 tgggtaatat agtgggattt tgtttttata aaaaataaaa aattagttag gtggggtggt 38160 atatgtttgt agttttagtt atttgggagt ttgagttggg atttaagagt gggtttagag 38220 tagtttttgg ggttggtagt tgggttttag tttgagttta ggaagttaag gttgtagtga 38280 gttgtgattg ggttattgtt ttttagtttg gatgtgtgat agagtgagat tttgttttaa 38340 aataaaataa aaattgttta ggttaatggt ttttttgggt ttttattttt ttatgaaggt 38400 ttggtgttaa gtaaaattta tttgaattgt tatgtttgtt ttttgttaat ttttgttagt 38460 ttaattttta gggttttagt taatgaattt aaaattgata gaaggaaagg gttttttttt 38520 agattttgtt ttgattaggt ttttgtaatt ttgtgataaa ggtttgaagg tttgaatagg 38580 aggatataag gtttgagtga gagagaattt tttttgttta attgttttta atttggaata 38640 ttagattttt tttgttttag atttaaattg atatatgtgt tttttttggg ttttgggatt 38700 ggaatgatgt tattggtttt tttgggtttt gggtttttag gtggatatta gagttgtaat 38760 atgggttttt ttgtgttttt agtttgttga tttattttgt taattttggt atttgttaat 38820 ttttgtaatg aggtgagtta attttttata ataataaatt tttttattta aatatatgta 38880 tatatttttt attggttttg tttttttgga tgattttaat ataattattt tgtgaatata 38940 gtaaaattat tgaattgtag attttaaaaa ggttaatgtt atagtatgtg aattttattt 39000 ttataaagtt attatttaaa tagtaataag aagttggtga gttttgtgta tttttttgta 39060 aataagagta gggatagtgt tgtttttgtt tttggatgtt tttagttttt agtttgagtt 39120 taggaatatt ttttatgtgt tttttttttt aattttgtag tttaagggtg ggggtggttt 39180 ttagtttggt attttttttg tagtttttta tttttttttt atattagtta atggatatag 39240 aggttttttt atggattttt atttttattt atttattttt atttttttga gatagagttt 39300 tattttgttg tttaggttgg agtgtagtgg tgtgattttg gtttattgta atttttgttt 39360 tttggatttg agtgattttt ttgttttagt tttttgagta attgggatta taggtatgtg 39420 ttattatatt tagttaattt tttgtatttt tattagaggt agggtttttt tatgttggtt 39480 aggttggttt tgaatttttg attttaggtg atttatttgt tttagttttt taaagtgttg 39540 ggattagagg tgtgagttat taagtttagt ttttttatag atttttaaaa gggttttggg 39600 taatatagat tgggatttgt taagttatta aatgattttt ttaaataaag aaggaagtta 39660 taaattttta tttaaaagga gtgggggatg gtaatagaaa tatagttagt tagaagttgg 39720 aagggtttta tttaatttat ttttaaggtt tttgggtaga agggataagg gaaaatttgt 39780 tttttaaata ttttatttgg tattttattt tttggatgta agatgtagtt gtgtatagtg 39840 gtagtagtga ggattttggt ttggtaggtt tttatatttt ttgttgaggg ttttaggggt 39900 tagggttgtt taataggatt aagaggaaat gattatagga gtttttagtt gttgggggtg 39960 gtttttgtgg ttttttgggt tatttttggt gaatttattt taaatttgga agaggtttaa 40020 gtttttttgt tttttgtatt ttaaatttta gttatgttag ttaggagttt tgggggatga 40080 gaaaaaattt aattaagttt tattgtgttg ggtgatatag gatttagaag gagaggggtt 40140 tttggattgt ttaagtttaa tgataatttt agtagttggg tttttaagtt aattagtttt 40200 ttttttttta gtagtttttg gggagtatta tggtgagttg tgaggagtta gtttagtatg 40260 gtatatataa tgtaggggtt tttttgtatt tttattttat aaatattagg gttttttggg 40320 ggattagttt tttatttttg agttattttt tttttattgt ttttttaata aggaatagag 40380 aaggagtttt tattgtttaa ttagatgtag aaattgatgt atgtatagag aggttatgtg 40440 tgatatggtt tggatgttgt tttttttaaa ttttatgttg aaatgtgatt tttgatgttg 40500 gaggtaaggt ttgggggggg tggggtttgg gttatggggg tggatttttt atggatggtt 40560 tggtgttttt tttatggtta taaagtttgg gagatttgat tgttatagag tttgggaggg 40620 ttgggtgagg tggtttatat ttgtaatttt agtattttgg gaggttaagg tgggtggatt 40680 ataaggttag gagtttggga ttagtttgat taatatggtg aaattttatt tttagtaaaa 40740 atataaaaaa attagttggg tgtggtggta tgtgtttgta attttagtta tttaggaggt 40800 tgaggttgta gtgagttgag gattgtgtta ttgtatttta gtttggttga tatagtgaga 40860 ttttatttta aaaaaaaaaa gagtttggga gttttttttt ttgttatgtg atgtgttagt 40920 ttttttttta ttttttatta tgaggaaaag ttttttgggg tttttttaga agttaagtag 40980 atgttggtat tatttgtata gtttgtagaa ttgtgagtta aataattttt tagttttggt 41040 tattttttat agtaatttaa aatggatgaa tataatgtat tagttttttt ttttggattt 41100 tatagtgtgt ttggttgggg ttgtgttttg gggaaatggt aattgtgagg tttttataga 41160 ttgggtttgg gttttaatta tagttgtatt ttagtgtttt gatattgttg agtggatgtt 41220 taaaaagtat tgttgggtga atgtgtgagt gaatgatgaa gatggaggtg gttgttggtg 41280 ttagggtaag gttttaggag tttggggagg tggtattagg tagtttaggt taatggttaa 41340 ttttggatag ggttaggagg tagttagaat ggttaaggat agttaaggga ttttaggtaa 41400 gtggttttat tttttttagg tgggtaggaa gtaggaatta gattaagggg tgttaggtgg 41460 tagtggtatt tagggggttt gaggagtagg tgtaggttta gtagggttgg tggtgttatg 41520 tgtggggttg attgtggttt tgtttattgt ttttattttt tggatgtatg ggtttatggt 41580 ttttaaggtt tttttttgtt tttatgttta tttttttagg ttttattttt agatgttaag 41640 ttattttttt atttttattt tttttgttgt ttttatattt gagttgattt tttttttgag 41700 ttttggtgaa attttagaga gtttagaggt gtagtttata tttttgtgtt ataaggtttt 41760 tgtagttttt atttttttgg gatattttat tttagagttg ggtgtgtatt tattttattg 41820 gattagaaat tttaggaatg tttattttgt atgtttttgt tttttatttt ttgtttgtta 41880 tttagtttgt ggttgttatg tggttgggtt ttggtagtta ttgtagttgg taatatataa 41940 ttagtatttt tgtgtttagg ttttgtgttg agttttttta gttttatttt tgtttgtttt 42000 taaaatggtt tttgatatgg taattattat tatttatttt ttagataaaa gattatagtt 42060 ttaggagagg aggaatggta ggtttgaggt tatgtggttt gtaataggta aatggatttg 42120 gtagttattt tatttttgag tggggttttt ttttgtttgt agattttgtt gaggttttag 42180 agtttggagt tagtgagttt ttattgagta taaggatagt ggtggtgttg gggttggaat 42240 aaggtaggga ggggtttttt aaattatagt tttggttgtg gatttatttt gggattttgt 42300 tttggttggg aattttgttt tagtttattt gggatatttt tttattttga gttttgtatt 42360 gggttgtgta tggggtttgt tgaatgagtg agggtaggag ggatggtgag tagggtggaa 42420 agtgattatg gtgggtaggt ttttgttgga agtttgaaat atttttggtg agtaggaaaa 42480 tattagggga agaggttata gtttttagaa gggtttgttg gggattgttt tgtagttttt 42540 ttattgggat aggtagaaaa tttagttttt ttttagggtg agtttaggaa gtttgtgggg 42600 gtataggttt tagttagggt ggtgtgtggg tttatttagg ggatgttgtt gtggtttaga 42660 gttaggttaa attttatgta ttttgtaaat aattatttat aataaataag gtttatttat 42720 tttttaagaa gagtaaaata ttataggagg tattttttta ttaattaaat atgttatagt 42780 gattttattg tgttattgag ggagggtatt agggtgtttg gtttagagta aattgtggtt 42840 agggggatgg gtatattgtt aaattggtta gatttttatt tttgaaaatg tgggttaaat 42900 tttttttaat aagttataag gaaatttagt gtgaatttta tgtttttatt attattggtt 42960 gttttggaag attgggagga ggggttttgt ttttttttta tttttggtta tagggtttga 43020 ggttataatt tggattggga ttttaatttt ttttttgggg aagaggttta tttagggtgt 43080 ttgttaaggt ttagtgtata aatatggaat ttgtttaatg tttgttttgg tatttttggg 43140 ttttttatat tgggtttttt tatttgattt tttaagtagt gagagtgatg ggatatgggg 43200 tgtttttagg ggagatttgg ggagatggag taagtttttt agtttaaggt gaggttttga 43260 ggtatggttt atgtagtgat gttttttatg ggaggtttga ggtatgatta ggagtttgga 43320 gatttagtag aggtttgggt atgggatttt tggtatgtag ttagagtgag ggttgaggtt 43380 gtatggatgt aagtaggtga ttttgtgtta ttgggtgtta tttgtgttgg gttttgtgta 43440 gttgttttta ttttattgag ttttagggag gtgaggtaat tattttaggt atatagtttt 43500 gggggtaaag gttggattta ggtgtgtttg attttagaat ttaagaagat aagtagagga 43560 gtttgagttt tttgagattg tagtgatggt ttagtgtttt aggatggtta ggttggtttt 43620 tgtagtttta gttaattgtg ttttttttta gttatttagg gttttagtgt tggtttttga 43680 gatttggtat tggttatagg ggtttatttt tggttgtgga tatttagtgt tggttattgg 43740 gatttggtat tggttgtggg gatttgtttt tggttgtggg gatttagtgt tggtttttga 43800 gatttggtat tggttatggg gatttgtttt tggttgtggg tatttggtgt tggtttttga 43860 gatttggtat tggttatggg ggtttgtttt tggttgtggg tatttggtgt tggtttttga 43920 gatttggtat tggttatgga ggtttgtttt tggttgtggg tatttggtgt tggtttttga 43980 gatttggtat tggttgtggg ggtttatttt tggttgtagg gatttagtat tgtttatggg 44040 gtttgttttt ggttttgggg agttagtagt gtttgtgggg tttatatttg gtggtgggga 44100 tttggtgttg gaggattttg atagtaaaat tatagaggtg ataggtaata gtaatttatt 44160 agtatagtgt gtggtttgtt ttagttatgg tatttttttt tattttgtgt ttttttatta 44220 taaagtttag tgtaggtaat gaagttaaga ggtggagaat ttgtaggagg atgtatatta 44280 tatttgtttt ttgtgtggtg tttttgtatt ttgggtggtt gagatttttt gttttttttt 44340 taggtttttt tgtgttaggt ttgtgttgtt ttttttggtt ttggttttta tttatttggt 44400 tttttagtta tagatagtag tgattttttt ttttatttaa tggggttatt gtttagttta 44460 ttattagttt ttagggttgg tagatgatat tggttatggg tagtgttttt tttggtttta 44520 gtatataagg tataaaagat attattttgt tttaagattt ttttagttat gtggtgtatg 44580 ggaagtggtg ttgggaattt tttagggtag ttttttgttt tgggggagat tgtgtttaaa 44640 tttttgagga aatgttgttt tttggttttt tttttgaaaa attttttaag gagattttgt 44700 gtggagtgtg tagggagaat ggagattttt gtgagattgt tttgggatag ttttatagaa 44760 attataaatt atttggataa aagttgaaaa tttgtggtta tataatgttg attatttatt 44820 taaatatttg ttgagtaagt atttatgatg tttgggaatt taggatgtgg attgataaga 44880 tataattttt atgtttgttt tagtgataga gagagagatg gtattattaa ttttgtttgt 44940 tgggggtttt tttggagggg gtgtgtaggt ttagggttga atttgtttag tggatgtgtt 45000 atttatgttt gtgtattttt tggttttgtg gtggtttttg gaataaaggt tgagagataa 45060 aagataagga tttgggggag ggaggatgtt tatgtatatt ttattgggga tattagtaag 45120 gatgattgtt tagtgattat ttagtgattg agttatttgg tgtttggagt ttggtattta 45180 tagagtaggg tgggggtagt aggttttgtt gggggtatag gtttgagaag ggagtgttgt 45240 tagttaggtt tgatgggata gagagtgaag ggtttttttt ttgaaggtta tgtagaggtt 45300 ggaggttaat gttagtaatt ttattaatgt tagttttttg agattgattt agagttgggg 45360 ttttaagagt agttttgggt gtttaggagt taagatttta tagagggtgt tttttatttt 45420 tagtttaggg aaagtgataa atttggagtg tttttgttta tggtttaatt attgaattta 45480 aatgaatgta ttgataaatt gtatttagtg ttatttatag ggaaaaggga gggaaaaaaa 45540 aaaaagaaag agagttaatt gtgtttaggt tggttggtta gggggaggat agatgggtta 45600 ttatttttgt tattttttag gttttttgta ttgatttttt atttttagta aaattaaggt 45660 ttagtttttt tttgtagttt tggagttggt tgggatgaag taatttttgt aggtagatta 45720 ttaggtttat tgtgatggtt ttagtaggga atttagttta ggttatagta gtttaggtgt 45780 ttgtagaagg tttagatttt tgggtgttaa gttttttttt tttgtatttg ttttggggtt 45840 tggtggggtg ggtagtgtgt gatttttagg gttgatgaaa gagaggagga agaggttgag 45900 tggtggtgag tttgaatagt taattttggg aggggttgag gtggggaagg tttttattgt 45960 tgttttatag gttttggagt aaggttttta tgattttatt agtagttggg taggtatagg 46020 tttaggtgtt gagtgtgtta ggatttttgt tgttttttgg gtgggggtga gagggatttt 46080 tatgggtttg taattagatt tgtgtttttt tagttaattt tttattaaat aaatttatat 46140 gtatagtgga ttgggtatgg ttgttatttt tgggagtttt tttgggaaag ttttttaagg 46200 ttttgttgag ttttgggaat aggtttttat ttgtttggga attgggttgg tatttaataa 46260 ataaattaaa gtttggtgtt ggaaggtaga attttgggat tagagtttta gttaagggtt 46320 ataagttttt taggaagttt tttttttaaa gagtggttgt gggatgttgg gagtttttag 46380 ggtggttagt ttttaggttt ttttaaagtt taggtggtat tgatgttttg tgttaaggtg 46440 agggttgtag agaggggttg gtggggagga gtttttatag tttattttgg ttattgattt 46500 tatttttaag tattgaaata aagttttttt tttatatttt tggttaggga gagagggtgg 46560 aagttttaaa tatttggggt gtatgggaaa ggtttatatg tatagaagaa ttagataatg 46620 gaagttgttg gtggtggtga taggtttttt aaaggggttt tgagattttt gatattggta 46680 gggaagttat atattgtatt aggtttgggg gtagggagaa ggggttttta aggatggggt 46740 tgtttttttt tgtggaagtg ttttgtattg tttgataaga gtagtttgga ttagttgtgg 46800 tataatagga agttgggaga atatggtggt ttaggaggtt ggttagggtt ggggagtggt 46860 taatttagag attttggttg tttaagtggg tttagggttt ttggggtgaa agtttttgtg 46920 gagtatagtg gatttagtgt ttggaggata gattttaggt ttagataagg tttttttttt 46980 ttttttttga gatagagttt tatttttgtt gtttagattg gagtgtagta gtataatttt 47040 agtttattgt aatttttatt ttttaggttt aagtgatttt tttgttttag ttttttgagt 47100 agttgttatt ataggtatgt gttattatgt ttggattagt tagtattttt agtagagata 47160 gggttttatt atgttggtta ggttggtttt gaatttttga ttttaggtga tttgtttgtt 47220 ttggtttttt gaagtgttgg gattataggt atgagttatt gtgtttggtt aataaggtta 47280 tttttgatat ggaatgttgg tttgattata gtgtttgatg gtttttgttt gtaattatgt 47340 ttttgttttt tattaaagta gggtttttag ggtagaagtt gtattttttt attttagagt 47400 gttttatgtt attttttagg tgtatatagt gggttttttt tattgtagtt gaattggttt 47460 tattattatt ataatgatag tttatagggg tgggggttag tgggaatata aagtggttaa 47520 tgtaatagtg ttttagttat tttgatatag aaatggttag gggatagaag gggtaagttg 47580 ggagttagta gtaatttagg tttttagaga tgagtattaa aaaaggtgag ttatattata 47640 ggtttttttt gattatattt tagtttaaaa gagatttaag gagaaataag aattttattt 47700 ttttaataag gatttgtata ttagatgtta agtaaatatt tttttttttt ttttgaaaag 47760 gagtttttgg ggttgttggg ggagttggtt aaagagaatg atatttatgg aaatatatgt 47820 ggttttatta agttttaagg taaggtggta atgaatggag gaggaaaatt tatagtatta 47880 ttagggaatg gggttttttt ttgttttttt tttttttaat gggttttttt atgtgggatt 47940 taaattaaat tttaatttta ttttgattta gtaggtgttg tttttatagt tttgaataga 48000 tttgttagaa aattattgtt taatttgttt ttgggtggta tatttttttt taggaaagga 48060 attataaatt tattttagat gagtagagag ttgtttttta aatttttgat taaaatatag 48120 tagattttat atgaaaaagt aaagagagag gggttaggga tgaagtgtag taggttggag 48180 gttgagttag tttttagagt tattgggatg gtgttttagg agtagatggt attgtttata 48240 aagttttttg tttttttttg ttttgaggtt ggggattatt ttgttggttg tatgatttag 48300 tttttggggt ttttttagta tgaaaagatt ttttgaaagt aggtttgtta gggagatttt 48360 ttagtttttg tttattgata tgtttttgta tggttgatat gtagtatgtt attgtagaga 48420 agtaaagtat atgtagatta gttttgttag tagtattttt tttttttgtt ttttttagga 48480 atgttttgta tatatttaat atatttagga atttagagtt gtgttgtagt agtagttttt 48540 tggattttag tgttggtgtt gtggggagtt ttggttatgg tattttgagt attgagatta 48600 tttttagttt ttagttagtt ggtttttggg agtttagagg ggtgataatt tgagtggagt 48660 gattttagag aaagtggtgg ttaatttgaa tttttttttg gtttttttgg aagttaggga 48720 aattttttgt gaaaaggaaa tatgttttaa gaagttttgg gtagtaggag aatttagtta 48780 tttagtttag ttggttaaat atttataaag agatagttgt gattatataa agttttattt 48840 ttttattttg aggttgaaaa tttggttttt gtgtggagat tgagtttttt gttatttttt 48900 ttttggggat tttgtttggt tttgttggtt ttgggttggg gtttagggat agtgtggttt 48960 ttggtattgt tattatggtt attagggttt gttttgtggt tgtgttattt gagagttttt 49020 gagttagtgg tgtaaggttg ggaagaataa aggagtagga tttattttag tagtggaatg 49080 ttgggttgtg ttggatgtgt tgagagttgt ggtttgttta ttgggttata tggtttagag 49140 ttgagtagag gattaaaggg gttttgtggt tgtggaataa ggagtttttt agagtgtggg 49200 gtagaggtag ggagggattt tgattgtttg ggaagggagg tttggtgggg aattgtttta 49260 agggggtagg gtgaggggag taggaggagg gggtaggtag agataggggt gtttagtggt 49320 aggtttggtg tagaagtaat ttgaaggtat gggagggatg ttaaggagtt gttatatgtt 49380 aaaggaaagt gatagggttt ttgggaagag tgagggggag ttgttaggaa gaagagaggg 49440 gaagaggttt ttagggattt ttggttatgt tgtttttgtt tttgtttttg tgtttgttag 49500 aggtggtgtt tgtgaggagt tttttttttt tagttaggtt ttgaaattga tttggatatt 49560 tttttttttt gtgttttgtt tgatattttt gttttttagg tgttttttta tttatttgtt 49620 tagatattgt tatagttggg tttttaggga gtatggttag ttattttaga aagttattta 49680 gatttgtagt tagggttgga atatagttat ttgggtttgt tttttttatt ttaggtgttt 49740 gttggttggg attatggaag ggagaaggag taggagagga ggggtagggg atgggggtgt 49800 agtttatttt gagttttttt tttgagagtt tttggattta gatttgattt agtttttgtt 49860 tttttagttt ttttagtttt tgggggattt ggttagtgag ttagtttttt tttttttttt 49920 tttttgtagg tttgggatgt gttgggattt agaggggtat aagtaagggg gtttttagag 49980 gagggagttg atattatagg ggttgggttt ggatgttggg atttgttaga tttattttag 50040 tgttatgatt tttgaattta agtgagttat ttttagtagg ggtgtggtta tttttatatt 50100 aggagagagt gtttgggagt gggtttgttt tgagggtttg ttgggggttg ggagggattt 50160 atttaaatgg aaagaagttt ttggtgatat tttttgaggg ttaggggttg aattttggaa 50220 gttatgtttt taggtagttt ttatgggatt ttatgttgag tgttgattgg gttttatata 50280 tttttatttt ttttattttg tatttttata tgtggttggg ggtgattgaa gttttggggt 50340 atttgttata ttggttaaat aggttagtta tgtttagtgg ttttttagtt agtagttatt 50400 ggtatttgat ttgttgtttt ttatttttta tggttaattt tttttttaag gttttttggt 50460 tttatggttt tttttatttt tatagtgaat ggttgtgggg agttgttgtt attggttttt 50520 gggtgttagg ttagagttgg gggagtgttt gggagaagat tgtatgtttg gagtttttgt 50580 ttttatttga atgggaggga ggttggtggt agattagaga tttgggtttt gagttaaata 50640 ttgaaattta aggttttggg tttgttattt aatatttgtg gaatttgatt ttttttattt 50700 ataaaatggg tattattaat attagttgtt aaaattatag taagatatat atgtttaggt 50760 taggaagtgt ggttatttag aaaatatagt tttttttttt tttaagaagt taattttttt 50820 agtattggga gtgagaagag tttgtttttt ttattgtttg tagtttagtt tagggtattt 50880 ttattattgg tttttaaagg gtagttttag aaattgttga taaaggatgt tagaaggaat 50940 ttttttttgg ttaggtgtta gggttaatag aaagttttga ggatgtagtt tttattatgt 51000 ttttgttttg tgggtttttt tttttttgtg ggtagaattt tttttttttg gttttttttt 51060 ttgaattttt ttttttttgt ttttggtttt aatttgtttt ttagtttttt ggttttttag 51120 gtttttttta gggtttaaga ttttgttttt ttttaagttt agtttttttt ttttttttgt 51180 ttttggattt ttgagttggg aggttagtat tttgggtgtt ttgttgaggt ggttgttttt 51240 tttgtagtgg ttttttttgt tgttattaaa tgagggtttt tagagtatag agaaggtatt 51300 tttggtttgg ggttgtattt tttatataaa gtttttgttt tttagtattt tttaaagttt 51360 tttattgttt agtatatatt tagtatttag gtagagtagt tttagagttt ttttggttgg 51420 tttttggttt aattttttag tagaaatggt atatgggtta tagatgtaat tttatatttt 51480 ttagtattta taataaaaaa tgtaagaata agttaggtat agtggtttat gtttgttata 51540 ttagtatttt gggaggttga ggtgggtaga ttatttgagg ttaggagttt aaaattagtt 51600 tggttaatat ggtaaaattt tgtttttatt aaaaatataa aaattagtta ggtatggtag 51660 tagttatttg taattttagt tatttgggag gttgaggtag gagaattgtt taaatttggg 51720 aggtaaaggt tgtagtgagt tgagattgtg ttattgtatt ttagtttggg taatagtgtg 51780 agattttata tttaaaaaaa aaaagaaaag aaaagaaaaa ggaaattatt aaaaaatgta 51840 agaataggtg atattaattt taatattatt tatttaatag agtttaaaat attattaatt 51900 taatatgtaa ttaatgtaaa aatgatagat atttgatatt tttttttttt ttttttgtta 51960 ggattttgaa atttagagtg tattttatat atatggtatt tttttatttg gaattattat 52020 attttaggtg tttaaatggt tttgtgtagt tagtggttat tatgttggat agtgtagttt 52080 ggagagtttt aatttttttt tttttttttg gttgttgggg aatagagttt tgttttgtta 52140 tttaggttgg agtgtaatgg tgtgattttg gtttattgta atttttgttt tttgagttta 52200 agtaattttt ttgttttagt tttttaagta gttgggatta taggtgtata ttattatgtt 52260 tggtggttat tttttgtatt tttagtagag atggggtttt attatgttgg ttaggttggt 52320 tttaaattat agattttaat tgatttgttt gttttagttt tttgaagtgt tgagattata 52380 tgtgtgagtt attatgttta tttttggata gttttaattt gattttagga taatattagg 52440 ttattagaga gttgttgatt tggattatat tatgatttga attttttaga ttatttttgg 52500 tattatgttt ataagttata tttagaggat aataggatat agtttggtga aatatatagt 52560 ggtatttttt ataagatatt ggtgaggtta tagattttat tattagtgtt atttgtttgg 52620 ggatatttta tttttagaaa atgtagagtt ttttttaaga aatgaatgtg gttaggtgtg 52680 ttggtttata tttgttattt tagtattttg ggaggttaag gtgagtatat tgtttgaggt 52740 taggagttta agattagttt gattaatatg gtgaaattta gttattatta aaaatataaa 52800 aatttgttag gtgtggtagt gtgtgtttgt agttttagtt atttaggagg ttgaggtagg 52860 agaattgttt gaatttggga ggaggaggtt gtggtgagtt gagattatgt tattgtattt 52920 tagtttgggt gatagagtga gattttgttt taaaaaataa ataaaaaaag aaatgaatgt 52980 tttaggtata tgttaagtat tttttagatg attttaaaga tattaattat tgtgattgat 53040 gatgattttt tttttttttt gggtgtgttt gttttgtttt tttagtttat aggtgtttag 53100 gatttaaagg tagtttgtta taggttatgg gatttggttg gtttaaaagg gagagtgagg 53160 ttattggaat ttttttagga gtgagtttga agtttggaat gttttttggt ggagggtttt 53220 gaagttagga ggtgatgtag atgtgggggt tgagatatta tttggggtta tttgtaaaga 53280 gggatattta ggtagtgatt ttaaggaaag agtaagggga ggagagggtg gtatatttat 53340 gtttttttaa tttttgtttg tttggaggtt tatgtatttt atatgttggt ttttttgtat 53400 ggatattttt ttaataagta atttattgtg tttatgttta tttattttaa agttatatag 53460 aattgtattt attaaaaatg aatttatgga gatagaaagt attttggtgg ttgttaaggg 53520 ttggagaggg tgaatgggga gtgagttttt tatggatatg gggttttttt ttggggtgat 53580 gaaaaagttt tggtgttaga tagtgttgat ggttgtatga tattgtgaat gtatttagtg 53640 ttattaatgg taaattttat gttttgtgta ttttagtata ataaaaaaat atatatttaa 53700 agtaatagaa tttaatgtgt tttttttttt ttttgagtta gtttgttttt ttgttttata 53760 ttttaaaatt agaagggttt tgagatatat tataggtttt tagggtaggt tgaataattt 53820 ttttttttta aattgtgtta ttttatgtgg taatagggat tttgtagatg taattgaaga 53880 tgttgagatg aagagattat ttaggtgggt tttaaattat aagtgttttt taagagggag 53940 gtaggttagg tgtgatggtt tatggttgta attttagtat tttgggaggt tgaggtaggt 54000 agattatttg aggttaggag tttaagatta gtttggttaa tatggtaaaa ttttgttttt 54060 attaaaaata taaaaattag ttaggtgtag tagtatatgt ttgtaatttt agttatttgg 54120 gaagttgagg taggagaatt gtttgaattt aggaggtgga ggttgtagtg agttaagatt 54180 gtgttattgt attttagttt gggtgatttt gttttaaaaa aaaaaaagag gaaggtagag 54240 ggagatttga ttgtagagaa ggaggaggtt gtaggaggat ggaggtagag gttggaggga 54300 tgtagttgta agttaaggaa ttttagtaga gttttttatt taaagttgga agaggtagga 54360 atggattttg ttaatatttt gattttagtt tggtgagatt gattggtttt tgatttttag 54420 tattgtaaag gaaggagttt ttgttgtttt aagttattga gtttgtgata agtagttata 54480 gtggtaatag gaagtgaatg tagtttttag tttatttttt tgtttatagt aatataggtg 54540 tttttttgtg tagaattttg ttaggtagtt agtgagtggg ataggatttt tttttgtttt 54600 tatttggggt tttgtgttgg attttttaag gttgttgttt ttgagatagt gaatttttta 54660 tatttataga gatttatttt aaagttgaga aagtgttttt tttaaggggt gttagaaaga 54720 aggttttaag gtgtttttgt tatatgttta tttgtttgtg ggtaatattt atagtttttt 54780 tttgtgattt atttaataga agggttatag gggagggagt attattggtt agtttatttt 54840 atagtaaggt tttattttgg aagttatagg ggatagttgg gatttttatt tttaatttag 54900 ttaattggga gaagagttta gaatagtttt ggaggttgat atttgttagg aagtgtggtg 54960 atatttatgt gttgttgaaa tatatagtaa tatagtagta gagaggaggg gatgtggttt 55020 tatagttttt tttttattta tttagtatgt atgtatatat atatatatgt gtgtgtatat 55080 atgtattaat ttttagtttt taggttttgt attttgtttt tgttaagttt tttggttatt 55140 attaagttag gttgtgagta tagagtttag tttttttgtt aatttttttt taatttattt 55200 tgggtaatat tttaatggga tgtagtagat gttttttatt aaatgttaag agtaatattt 55260 ttttttattt tttgtgagtt ggtggttgtg tttttgtatg ggggtgtgga ggaaagggtt 55320 ggggagtagg aatgtggttt tgagggttgg tatgtatttg tagttgtgat gttttgaggt 55380 agtttatatt tttatttata gattaatttt gagaaggggt tgggagtatt tatagttttt 55440 gttatttttg ggttggtagg ttggggaaat tttgagtagt ttgagtgaag gttgttttta 55500 ggtaggtatg gtgggataga ggggtttttg tatatttttt gtgaggtagt gtagttgttg 55560 ggttgtttta gtatatttgg gtgatatgtt ttttttttgg ttttttttta tttggtttgg 55620 gagaatgttt aggatgtttt aattttaaaa ataagtaaat tttttttttt tgatttattt 55680 atttttttaa attgtgaatt ttttttttgt ttgaatagtt taatttttta aagtaggttt 55740 atattatggt ttttagtttt ttattgttta tttatttttt agtttgagtt atttggtgtt 55800 tgtttgtttt attattaatt tagtttttga aaaaattttt atggttagta tttagtttta 55860 ttttatttga ttttgagggt agtgtttgat atgtattagt tggttttttt tttttttttt 55920 ttttttttgt attttttagt gttggggttt agatagtttt taagggtttt tttgtttttt 55980 gatttagttt tttggagtga ttatattttt gttttagttt tttagtttag ttgttttttt 56040 atattttgtt ttaggttttt tttttggaat attgtttgtt tttagagatt taagttttta 56100 ttttttatat tttttttttt gatttttagt ttttttatta aagttttatt ggttgttttt 56160 ttttggtgtt ttaaattagt ttttttttgt ttagatttta taaggttagt ttttatttta 56220 tgattgtttt tttggattat tgggattatt ttttattaat atttattttt tattttgttt 56280 ttttttgttt atgtagggtt ttgttggagg attttttttg ttttattatt ttttttttta 56340 aatagttttt taggtttttt tgttaaagtt gaaatttttt ttttgtattt gaggattttt 56400 gtaatttggt taatttattt ttaagtttga atttttattt ttgtttaagg agtttatgtt 56460 ttttagttag gttttattgt tttgtaaatt ttatttaaaa ttttttttgg taaatgttat 56520 tatttttagg aagttttttt gatatttttt attatatgtg atttttattt ttagagttag 56580 attttgattt ggagattttg atttttattt atttttgttt tttttgagtt ttttaggttg 56640 taggttttag tttatgtttg tgggtttttg tagtaggagg gtttattttt atttttttaa 56700 gaagtgtttg ttttattttt tgttaagttg taatttttta taagtaggta tttttaatat 56760 gtttttttat tttttttttt tttttttttt ttttttgaga tggagtttgg ttttgttgtt 56820 taggttggag tgtagtggtg tgattttagt ttattgtaat ttttattttt taggttttaa 56880 gtgatttttt tgttatagtt ttttttgtag ttgggattat aagtatgtgt tgttatgtta 56940 agttaatttt tttttgtatt tttagtagag atagggtttt attatgttgg ttaggttggt 57000 tttaaatttt tggtttgaag tgatttgttg attttagttt tttaaagtgt tgggattata 57060 ggtgtgagtt attgtattta gtttaatatg tttttttata ttttttttga aaagttatta 57120 ttatattaat agtgtgtttt ataaattgat aataatttaa aatgtgattt attattaaaa 57180 gtgtgatttt atttttaaat aatattgttg gttgtggttt gtagttagtt ttattatttt 57240 tgtgtgatga ttattttgta gattagtaat ggttttaggt ttatatttaa tttaattatt 57300 ttgttttttt aattttattt ttttttgagt taatattaag tgtgttttag agttgtaaat 57360 ttatggttga tataaaatta ggatttttaa tatttaatat aaagtaattg ggttttgtat 57420 tggttttaat agtaattata aattatgttt gttttttgta ttgggtatat tgtatttagt 57480 ttataatatg tgtttttgtt ttttttattt tttttattaa gatggtatat aggtttaaat 57540 ttgttttttg ggagtaattg attttttttt ggaagatgtg agtagttttt atattatatt 57600 taagaagata ttgttataag attttatatt ttttatttta gtttttaagg gtttatttat 57660 ttttttaaaa atttatttgt tttgttataa tatgtgtttt ttttttttta tttgtttttt 57720 taagatatag ttttattttg ttgtttagat tggaatgtaa tggtatgatt ttagtttatt 57780 gtaatttttg ttttgtgggt ttaagtaatt tttttgtttt agttttttaa gtagttggga 57840 ttataggtgt gtattattat atttggttaa tttttgtatt tttagtagag atggggtttt 57900 attatgttgg ttaggttggt tttgaatttt tgattttagg tgatttattt gttttggttt 57960 tttgaagtgt tgggattata ggtgtgagtt attgtatttg gtttataata tgtgttttta 58020 tttttttttt tttttttatt aagatagtat atgggtttta agtttttttt tttttttttt 58080 tttttttaag attagttggt tgggtgtagt ggtttatgtt tgtaatttta ttattttggg 58140 aggttgaggt aggtagatta tgaggttagg agtttgagat tagtttggtt aatatagtga 58200 aattttgttt ttattaaaaa tataaaaaat tagttaggtg tggtggtggg tgtttgtaat 58260 tttagttatt tgggaggttg aggtagggga attgtttgaa tttgggaggt ggaggttaga 58320 gtgagttgag attgtgttat tgtattttag tttaggtaat agtgtaagat tttgatttaa 58380 aaaaaataaa ataagtggga agaggggaga tagtggaata aggagtttaa tttgtaattg 58440 attgtgaata attaattgag ataatttatt atttttggat tagttatggg ttttattttt 58500 tatttgtttt tttgagttat gttttttagt gaaattttat atgtatgtga ttaaatttgt 58560 tttttttttt attaatttat tttgagtgag tttaatttat agatttttaa atattgaatt 58620 taagagggta gaggaaatgt attttttttt tgttataaaa atattttatt tttttattgt 58680 agtgttgttt gttttattta tagttggtaa tttggatttt gttttttaaa gtttatgaaa 58740 gtaggataga ttgtttgtag gatgtttttg ttataaaagg agggttaggt ttggtaggag 58800 gaaagaaatg gaagtggtaa atgtttattt tttgtgttag atagaggtat taggtgttta 58860 ttgttttggg gagtaaatat ttttaaaaat ggaaagaaaa atttttagtt ttattggggt 58920 gtaaaaagtt atgatttttt ttgtggttaa atggttgggt ggtttgggag ataagtggta 58980 gttattttga agtttagttt atttgtttgt aaatggaggg taatgaaatt atttgttgta 59040 tgggtgtttg ataggttgtt gtttaaattt tttgtttttt tttatggggt tttggggaag 59100 attatatgag ttagtaatat aaaagtattt tgaaaattat atgaagtgtt taagtatggg 59160 ggtgttggtt gattttaggt ttgtttttat aagttggtag aaaatttttt agagagggtt 59220 ttgttttttt ttttggggta ggggttgtag tgttagattt gatggtattg gtggttgttt 59280 aggttatttg gtatgagatt gttgttagtt ttagatttat tttaagtttg ggagggaagt 59340 aggttggggt gggggttttg aaatttttta tatttttggt agagatatta gggtaggtaa 59400 aagtgttatt tatggtaaat taagaagttt gtttgaattg ggtttaaatt agtttagttt 59460 agaatggagg ttagttttat tttttttttt tagaattagg agtttagtat attagaggtt 59520 gagaaaatgt tggaatagtt tttttatttg tttgtttaga gatagggatt ttaagttatt 59580 ttttttttta gtttatttta taaatttttt gtgttagatt ttttttgttt aggagttata 59640 ggttttattt gggagttatt tagggtttta aggtttttat tatttagttg tttattttat 59700 taggttaggt ttgtaggtat ggagattagt aggatgtggt ttaaatttgg ttgtatgttg 59760 attagttgag tgattttggg tttatttttt aatttttggg aggtaatgtt tttttatttg 59820 taaaaagggg aaagggttta gtgaggagag tgataagtaa aggagatggt atttgtgtag 59880 atggtattgt gtgggtgttt agtggatgat tatgtgttat ttttttgttt tttttttttg 59940 tttttgtggg agtgtgggta gtagggagtt aagaggaagg gagtagttgt ttgtttggga 60000 tgtaggttgt tttgaattgg aagagaaaaa ggaataagta gtagttgttt attgataagt 60060 tttatgtatt tgtgttttaa aattttaaag gtgtatttga aagatttttt gggtaaattt 60120 ttttttatag atatatgaaa gttaggtgta gtggtttatg tttgtaattt taatattttg 60180 ggaggtgaag gtaggtggat tatttgaagt tgggagtttg agattagttt ggttaatttg 60240 gtgaaatttt atttttatta aaaatataaa aatttgttgg gtgtggtggt gggtgtttat 60300 aattttagtt atttaggagg ttgaggtagg agatttgttt gaatttgaga ggtggaggtt 60360 gtagtgagtt aagattgtgt tattgtattt tagtttaggt gatggagtga gattttattt 60420 taaataaaaa taaatttaaa aaaaaggtat atgaaaaagg taaaatgtta tgagtgtttt 60480 gttgtaatgt gttagttata aatgggaatt ggaggatttt ttaagttatt ttttttttta 60540 tttttttttt ttttgtatat gtattaatag ttttttgggt gttggtagta ttaggggatt 60600 tggggtgttt tataggtttt gtttgtttag attttagagt taaggaggag atataaaagt 60660 taaaataggg tggtaagtgg aataaatggg gattagatgg ggtaatttgg tagtatttgg 60720 taaggttttt tttaatgagt ttttaaagag gtttagtttt taggggaagg aggtgtttta 60780 ggtagtgggg gtttgtagag gtgaaggttt agggtggggt ttttagggaa gttgtttagg 60840 atgtttgaaa ggaggggagt aatttatgag tttggtgata gggttggtta taaagtgtta 60900 tgaagtatta attaggttgt ttattagttt ttaggataga aagattatag tagttaaggt 60960 gtggggattt gtttatttga tttttattta gtttagaaaa tgattgtttt agggttatag 61020 gtaatagttt aagttttgta agttgttggt tatagggtgt agttgtggta aggtggggat 61080 gtttattagt taagtttttt aggatttttg ggttgttgga tatgtttgta ggatgttatg 61140 ggggtaggtt agattagggg tatttttatt ttttttttta ggttttagtt tttaggttag 61200 agtgtttttt ggtttttggg gtttttaggg ttgtagatag atagggagag gtttgtgtta 61260 tggtgggtta tttggttttt gtaggaagtg gttagaggtt ttagtatttg gatatagtag 61320 ttattttttt aatttttgtt aatgttgttg ttgtttgggg tttatttttt ttaatttttt 61380 tttttaatta gggaggaaag tattttggag taggaattgg gttatttagt ttgatatttt 61440 agtatgattt tgtatgattt tgggttagtt atttaatttt tttgggtttt tattttttta 61500 tttgtaaatt aggtagataa ttttttaaag ttttttttag ttatagaatt ttaagtgtta 61560 aaataaaaaa aatttataaa aaggaaatat gtgtttagtt tatatttttg tttttatttg 61620 ttaaaagggg aaatggattt gttatggggt tttttttttt taaatagata tgggagattt 61680 tttttatgat tgtagaattg gagtagttta gaggagttta gaatttttta gagtttgaga 61740 tttatagggg aatttatttt aatttttttg ggatagaagt attgttgttt aatggtattt 61800 aatttttatt attgttgtag taaatgatta tatatttgtg atgttaaata atatagatta 61860 gttttatatt ttattttatt aggttatagg gaaggtgttt atagggttgt gtattttttt 61920 gaggttgtag gggagattgt gtttttttgt attttttgtt tatttgtatt ttttggtttg 61980 tggttttttt ttttttttta agtttttttt attgtatttt ttagatggtt tattgtgttt 62040 ttaaaaattt ttgtgatgat agtgggtttg tgtggattat ttaggattat ttttttattt 62100 taagattagt tgattagtga ttttagttgg ttttgttatg ttatttaatg tagttttagg 62160 tgttggggat taggatgtgt ttaattttgg gagttattat tttgttaatt ttaagatata 62220 ggttttggag ggagatgaag ggtaggatta taggtttagg aggttgtttg tgtgggtttg 62280 aattttggtt ttattattaa ggaattgggg gagtatatta tttgtaaaat gggggttggt 62340 ggggaattag ttttttggtt gttagtgtag agtgaggtag tgtgtgtagt gtttggagta 62400 gttttgtgag tatttgtttt ttttttgtta aatttataag aattgatttt ggtttaatgg 62460 tttttttaaa tttttagttt tttttggtta taaggttagg agtatttttt tgtagggtta 62520 tttaagtttt tagttttttt gaaagttttg gtttatatga tgttggaagt agatgtgttg 62580 tgggttgttt atttatgtat ggttattgga gaggtttgga tgatgttgtt tttaatgggt 62640 gtatagtgta gggtagggtt aggtattaat aattagttat agttattagt gtaagtaagg 62700 ggtttttatt gttatttttg gtttggggtt agggagaagt tttgggaggt atttgatttt 62760 tttataggga gtggggttat aggagaatgt atttgaaagg ggttgggggg tagtagaaag 62820 ttttttttag aaattttatt tttggtttgt gatagatgat ttttttaggt tattattggg 62880 gtttatttgg gtttttgtag tatggagttt ggttatttta gaaggatgat tgggtaggtt 62940 agggttattg gtgatggtga tggtaggttt ttttgaggtt tttttattag aagtattagg 63000 aggttagagt agttgataag tttttatttg gtttttgagg ggtagaaggt tttgagtagt 63060 tttttgattt tttgaggttt ttttatttta ttgagagatt tttgagagta ttgagagtta 63120 ttttttggtt tttttgtgag agagttggtt atataaaggt agttatatat ttagtaagat 63180 gaatttataa tttttgagtt taggtttatt ttggtttttt tatagggagt ttttgggggt 63240 gtggggtggg ggtgtagaag ggaggggttg gtgttttatt tttgggaatt aggttatgag 63300 ttttggattt aggttaaatt atagaggttt tatttttttt taggtttttt gttttttaat 63360 tatttttgta tagggtattt tttttttttt tgtagggttt tattggggtg gggtgaggag 63420 gagttataga attatagtag ttgttatatg ggggtgttaa ggtagggatg ttgatgttaa 63480 ttgaatgggt atgggaaggt agagtaggag gttggtgttt tgggtttggt taggttgtgt 63540 gattttaggg aatttatttt attttttttg gtttttagtt ttttttattg taaattgagg 63600 gagtgaggtt aggtgatttg tataattgtg tgaatttgtg ttttgtattt tttatttatt 63660 attttaaata atgtttttaa attttagttt tttaatgttt tggtattttt ttgtttgaga 63720 aatatttatg gttgtttttt atgttgtgtt ttaaatatag gtattttggt ttttttttgg 63780 gtgtttttat tagggttaga atgggtagtt tattttgtag gaatttttaa ggatttttag 63840 ttatttttag gatgggggtt ggttgtttgg aagtggtttt tgtttatttt tgttgtagtt 63900 tttattatga ggttagtgta gtaaaatagg aggtgtaggt ggttggggtt aggggttagg 63960 ttattttttt tagtggggta ggagaggggt gagaaaagtt ggatattgat tattttaggt 64020 tgagggtttg tgtggaggag ggggtttatg gtaaaggaag tgggaggatg ggaaggagtt 64080 tttgttggat atttttattt tgttggtttt agttttgttt ttgttttatt tgtggggaga 64140 aagtgaggtt ttttgttttg ttaaatttta gtaatgaatt ttatatttat tttatttttt 64200 gtttattgga aatttttttt ttattttttg gatttgtttt gaatagttgg gttgtagaag 64260 ttggtggaat gaaatatgta gggtggttta gaggggattg tgttgaatag tgttgtgttt 64320 ttgtttattt ttttttttga agataaggtt tttttgtttt tgtttttttt ttgggaaagt 64380 tggagagggg gttgaggaaa tgggatttat tattaatttt tttgtgtatg ttggttttta 64440 gtaggtattt ttatattttt taattaggtt tgtagggtgg aaaggtagtt gttgagttta 64500 atttaatttt tatttagttg tggaagttag tgtggatggt aaagtattta tgtataaata 64560 tatatatgag gttgaggtta agagaatatg tgtttagttt ttttttggtt ttttagtaat 64620 gtttttatgt tttagttttg ttttaagttt taaatggtgt aaggtttttt taggtggagg 64680 aatggaagtt tttaagaagt ttgtgtttta gggattatat agaggtaggg tttaggagta 64740 aaggttttta gattttgtag tgtggtgttg gtaagtttgt gttgttgtat ttatattgtt 64800 ttgggatgaa ggtgatatgt tgattttttt taggtggttg taggatagtt aggaggaggt 64860 gagatgttag ttaaaggtag ttatagataa tagtattatg gattattaga aatgttattt 64920 ttgtgttaaa gtgtttgttt tttttagttg ttttattttg tgttaatatt ttttgggagt 64980 gatatgtgtg agattgggtt gtgttgatga gtgattattg gtatttttag attatattaa 65040 ggaggggtta ttttgttgtt aattaggtgt agggtaggtg gtattggggt atgatgattt 65100 gtttggtatg gttgttttat tttttttttt gtttgagtat aggttggtag gtttagagga 65160 gaggaggaaa tagagttatt atggggggtg tgtttagggg tgagttattt taagaagtta 65220 tagaattagg gtatgggaga tattgtttag ttttgttatt aatttgttgt gtgaagttgg 65280 ttaagttatt gtattttttt gggttttagg ttttgtaatt agagggttgg ttgaagaggt 65340 aaatgatagt ggttagggat gggggtattg aagttagatt ttttgtattt ggattttttt 65400 tttgttatgt ttagagggag gtttgggtag gttatttaat atttttgggt tgtgggtttt 65460 ttattggtga aatgggaata ataatagaat taattttata gtgttgttgg gaggattaaa 65520 ggggatattt attttaggta aagagttttt aagatagttt ggggttttta ggaagttttt 65580 gttattatta ttggatatta ttatttttgt tatggttgtt agggttttgt ttagtattgg 65640 tagtttgatg ttggtagagg aagggtgagg tttttgtttt tttgtagtgt tttttttttt 65700 tttttttttt tagttatggt aataatagtt gaagtttatt tttagtttta gtgattggtt 65760 atttttttga attaaggatt gaaggtttta ggtttgttat ttaaggttta ggtgtaagag 65820 gggtgagtta ttggtttttg tttttattat atttaggttt ttatatgttt ttttaaatag 65880 gtttttgttt tatgtgtaag agaagatgtt aatttttatg tttggggtgg gggtgtttat 65940 aaatgttttg gatgtgagtt ttgatggggg ttatggtgta ggttttgtta gggtattttt 66000 aattataggg gattatttgt agtttataga gggttttttg taggttaatg ggattttgtt 66060 attttggttg ttattttgtt tagttatttg gtaaggaaaa taggttgtag atttagaggt 66120 agtatgggtt tatatgttag tgagataata taataaggga aggatgtgta ggatgaggga 66180 gttatggaga ttttattgta gttttagtta tttattagta gattttgtgt ggatgttggg 66240 taggttattt tattaatttt taggatgttt ttgtaggttt tgtgggtgga tagggtgaat 66300 ggaggtataa ggagggtaag tttgataggg gttggggttg ggtttggagt tagaatttta 66360 gttagttttg ttattgtatt ttagggtatt ttttgtagat agtaggttaa agtaaggttg 66420 tttagattaa aggggaaggg gttttgtttt ttttattaag ggttttttgg agattttaat 66480 atagattttt agtttataga tattaaattt agggtttttg agaagtgaga aatgtgaaaa 66540 atgtatagaa tagttgtagt ttagtgtttt taatatgtta gatttatata ggtatatata 66600 gtgtttttgt agaggttaga aagttttgtg ttgggaagtt ttttgattgg gggaggtttt 66660 atagtaagtt tttttttttg tttatttatt aatgggtgga aggttttaat taggattata 66720 tgggaagggt tagtgggagg ggtagagagg gaaaatgaat aggtaatatt aagtgtttgg 66780 ggtggggggt gtaggggata tttaggaggg gagggtaggg gtgtattttt tatttaattt 66840 atagggaatg ggggtttggg aggtgtagga gaaggttttg gtatttttat tttttttttt 66900 ttgtagattt atttatagtt tgtttatggg tagttagatt tagttatagg ttagatgttt 66960 gttttagttt tatttttttg gtttattgaa agtaagttag gatagtgagg gggatgatgt 67020 tgttattttt ggtatggtta tgttgggttt tggggtgggt gggaatgtgg ttggggtgtt 67080 attttttttg gttgttatag gtataaaagt ttttttgtgt tttagtgtta tatgtgggtt 67140 ttttttttgt tgttttaata ggatggatat ttaagtagat tttgttggtt ggggggggtt 67200 tttgtattta gttttatttt gatttagtga attttttttt tgttttttgg ggtaggagtt 67260 attaggttgg gttttaggta atggttagtg aaggggttgt atggaggggt tttttaggtt 67320 tataggaagg gaggtttttt ttttttgtaa tgtggttgta gtattttgtg attgagaggg 67380 atattatggt tggagatggt gggatggagg attttttata gtatttttga tgtttagaat 67440 attttatttt gtataaaaaa gttttaaatt tttttgaggg ttgaagttat ttagagttgg 67500 ggtttttgtt ttttaggtta aaagtatttt gttggagtag ttgagagtat agtgggaggg 67560 gaggggtagg agggaatagt tttgttatgg tgatagggga ttttttgatt ttaagagggt 67620 ttgtagatat tattatttat ttttagtttt gaattgtttt ttgttaaggg gttagaaatt 67680 tttgggaggg ggattatagg gggttttgtt tatgagaata gtgattgtgg ttaggttata 67740 gtttataagt tagtaatttt gtttagttgt tgtggtggtt tttttttgat ggtttttaga 67800 aaaagtgttt tattttttgt tattagtgtt ttgaaattta agaatatttt ttaaatagta 67860 attgtagtaa aagttaatgt tgtgtgagtg ttgtaggtat tatttttagg gttttatata 67920 ttttttgttt agtttttata aaaattttat tttatttttt tttttgtttt ttttttttaa 67980 tagtttagaa aatgagtatg gaagggttaa gttggtttga ggaggggttg gtggaatagt 68040 ttgagggttt agtttttaag aattttatat tgtaaaggga atttttgggt tagggagtag 68100 ggtatagttt ttattttttt atttttgttt ttagtattag gtttgatata gatggggttt 68160 tggttatgaa taaatgaata agtgaatgag agtttgttga gggaagaagg tgatagggat 68220 aagggagaaa taaagtagtt aatgttgttg tgatgatgat gatgttaatg gtagtattga 68280 tatgtgggtt tttgttatgt taggattgtt ttaagtattt tgttttatga atatttttgt 68340 tttttattat gttttgagtg gatattttta ttagtttatt ttatagaggg gaatatagtt 68400 gagtgtattg gttaaggtta tgttgttagg aaaggttaga gtttaggtag tatgtggttt 68460 tttagttggg ttttggttta tatggtttta taggtagttt tatgaaatat gtagagagag 68520 tatgtgaggg gtttttttgt tgttttttat ttttagttgg ggtttatttt ttgttgaaat 68580 ttttttaatt tgtttttaag ttttgttagt tatgaaatat ttttttgaat atttagtatt 68640 atttttttat ggttatttgg ttttattttt ttatagggta agttttgggt gaaaagtaga 68700 aaggatgaaa atttttgaga gaggtgataa tgtggtaatt tttttttttt tttttttttt 68760 tttgagatag tattttattt ttgttgttta ggttggaatg tagtggtatg attttggttt 68820 attgtaattt ttattttttg ggtttaagtt atttttttgt tttagttttt tgaggagttg 68880 ggagtatagg tatgtgttat tatattaggt taatttttgt gtttttttgt agagatggag 68940 ttttgttatg ttgtttaggt tggttttaaa tttgtgggtt taagtaattt gtttgtttta 69000 gttttttggg attatagatg tgaattattg tgtttggttg aggtggtttt tatataaagt 69060 agagaaaatt atttttagtt taaaataaat taataagtat tgagtgttta tgtagaaaaa 69120 gattagaagg aaatgtgaat atgttaatag tgtttgtttg gaggatgtaa ttattattga 69180 ttattttttt tatatttttt aatttaatta ttttgttata agtaggtgtg atttttaaaa 69240 ttataaaaga taaatgttgg ttttttgttt gtgttttgtt ttttgagata gggttttatt 69300 ttgttattta ggagttggag tatagtggtg tggttatagt ttattgtagt tttaaatttt 69360 taatttaagt aattttttta tttgagtttt ttgaggagtt gggattatag gtaagtgtta 69420 ttatttttag tatttttgtt gtttagattg gttttgaatg tttggtttta agtgattttt 69480 ttattgtagt tttttaaagt tgggattata ggtgtgagtt attatgttta gtaaagattg 69540 ttttttaatt aggaagatag atgtttttta gtattttttg tttttttttt tttttttttt 69600 tttgatatgg agtattgttt tgttgtttag gttggagtgt agtagtatag ttttggttta 69660 ttgtaatttt tgttttttgg gtttaagaga tttttttgtt ttagttttta gagtagttgg 69720 gattataagt gtgtattatt atatttggtt aatttttgta tttttagtag agatggggtt 69780 ttgttatgtt gattagtttg gttttgaatt tttgatttta agggatttat ttgttttggt 69840 tttttaaagt gttgggatta tatgtgtgag ttattatttt tggtttgttt tttagtattt 69900 ttaatttttg ttttttggta ttatttggtt aagtagatga aaagttttag tgagttgtta 69960 gttggtatta ggttggggtt ttttttaggt agttttaagt ggttaggatt tggttttttt 70020 tttagagttg ggtttagaaa ttaagattgg gaatgtgtga tggttgtttt gtgggttttt 70080 gttatgaggt tatttttttg gttttagtga ttggttgttg gttgtaggga gtatgtgggt 70140 ttagttaggg tttgtgttaa tatggttttg ttttatttat ggtttagtgg gtttttttat 70200 tttttgttgt atgataattt taggaaaaat gttaggaggg agggagttgt tgggggtgtg 70260 ataggagaga ttttttaggg atagatttgt aaaaattgtt ttaaagtttt ttttaaggat 70320 ttttaaggtt tttattgttt tttattgata ggttatggtt tgggtagaga aagttgggga 70380 tggagttggt ggggggaggg tggttagtat ttgtaaggta aggagatgag ttgggagaat 70440 aggggttggg agggtagttt taggttagtt tttgttttta gaattattgt tttttttttt 70500 tggttataaa gtgaggttgg ttagatatag gtttatttta taggttggga ggttgggtgt 70560 gaaagtattg tgtttgtatg gggtatttta tggtgaatat tattagagtt aatttttagg 70620 gtttgttgtt ttatagggaa gttagtgtaa ggtgtttatg gaatttagaa gtatttaaag 70680 gatttgatag ttatgagttg ggaggattta gttttgtagt aggagaaaga gaggtagaga 70740 gataggtttt gtaatatttg ttttatttgt tgtgttgttt tgagtatagt ttattttttt 70800 gtggttttga gttttagttt tgaggttttt aagatttttt gggtttttgt agtttaggat 70860 gtttatttga aaattaggtt tagttagtag ggtttttttt gttagtttat tattggttag 70920 tttttgttta gtatttttta gtttattatt tttatttgtg taaattttat attagtattt 70980 taagtttttt tttttttagg aaggagattg tttttagatg tgttttttgt ttttttttga 71040 ttaaagttta gaaaatagga attagttttg tgtttttttt ttttattgaa ttgttggttt 71100 ttttggatgt tttttttgat tttttgttaa tatttttata atataattag tttttagttt 71160 ttttttaaat gtaattggtg agtatgttgt agtttaggtg gatggtgatg tttttatttt 71220 gtaatttgtg agagttagta tattttttag ttaggtgggt tgtaggagtt agttgtggtg 71280 agggtaggag gtttgtgtgt tgatggtatt ggtattatta aaattatggt tagattaagg 71340 ttatggttaa tgagtttttt tatttgtaat ttttttttta ttaaggtggt tttagtttta 71400 gttttggttt tagttttggt tttggtttta ggagttgtag atatattttt aagtttttat 71460 tttaggagtt tggttttata tatattggag gatatggagt tggggtataa atagttaaga 71520 ataggtatat ttgtaattag gagtaggggg tggagggttg ttgagatgtt tttattttta 71580 ttggttgttt tttttgatgg tttattattt attatatatt gattgtataa ttagggttgt 71640 gatatgtttg ttttttatat tatattatta aatttttaaa tttgttttta atttatatat 71700 gatgaggtaa atttagagtt aataatttgt ttattagttt ttgaatttat gggtggtttt 71760 aatttttttt tttttagttt ttttgggttt atatgagtat tgaggtataa gggaatttta 71820 ttagttggga agtgtgtttt ttttttgttg attttatagt ttttttagtt tgtgtttgaa 71880 gttgttaata tttttttatt tagtattgtt ttttgtagtt tgagttgttg ttgtgtgatt 71940 tagggttagt gttttaattt ttttggatta tatttgtaag atgaggatgt tgttgtatag 72000 tttattttaa atggttatta agttgtttgt atagttaata tttgttgagt ttgtgatatg 72060 attagttttg ttttaatttt gaatgtggta tttttattta gtttgggggt ggaattgtta 72120 gttttttttt ttttggataa ggaagttgaa aggttttaga aggtattaag gttagttgat 72180 ttgttagtag gtatagtgtt tatttgttat ttatagtttt tttttgattg ttttgtttgt 72240 ttttttagtt gagattttgt gtgtatttga atattttgtt aatggttgaa tttgtattag 72300 ggttattgtg ttagttgggt ttgttaggtt attgtttttg agttttgttt aaggtagggt 72360 tagtgtttat attttgtttt tttgttagtg ttttatttaa ggttttggaa aggttttgga 72420 gttagagatt tggttaaatt ttggtaatgt tttatatttg ttgtgtgatt atgggttagt 72480 gatttagttt ttttgtgttt tttgggttgt tgtgagggtt ataggagatg tatagagggt 72540 tttgagtttg gtggttggta tgttgtaaag gttagttatg tggtgtaagg atggtattga 72600 tgataataaa tgaattgaat gaaaattagg ttaattgggt ttggggaggg gtgttggtta 72660 aatagatttg agtggattag gattttgtat atgatgagta agtgggaata gttttaaata 72720 gtaagttggg taggtttagg atgatttagt tttgggtgtt gtttagggtt tttttttggt 72780 ttttttgttg gtttggtttt tttttgtttt agtttgattg tttttatggg ttttaataag 72840 tttttgatta ggattgaggt agaatagata gggtttaaga ttttgtaggt aggtatagag 72900 tgtggatggt aaaaggagat gttttaggtt ttttgttgtt tttttttttt tgaaggttga 72960 taatgttaat ttatagaaga agttgttttt tttggttttg gattttattt taatatagtg 73020 tatgaggtag ttgtgtttaa ggggtgtgat tatttttgta gatggaattt atttattgtg 73080 tttagtttat tgttagagtt tggaggatgg gggaagtgag gtggggtatt ttttatagtg 73140 aagggaaaat ttagtttagt tatttttttt tgtgttgttt ttggaattta ttttgttatg 73200 gttttatttt aatttagttt tttaaagttt tagagagttt tgtttttttt tttgtatttt 73260 attttgttta tttgtgttgg gttagttttt tagaagtttt gttttttgtt atttttaggg 73320 tattaaggtt ggttggtggg tttagggatt tttatttttt gatttagttt tagtggttta 73380 ttttatattt attggtattt ataggtgtgt tttttatttt tggtttttgt ataggtggtt 73440 ttatattttg ggagtttagt tttttttaag gatttatgtt agagtatagg gatttttgtt 73500 tttgattttt ttttagtttt aattatgagt agtttatgtt atagtaattt tttagttgtt 73560 tgtagttgtt tgttaagtta tgataatggt ttttgttttt taatttaatg tttgtatata 73620 gataaattgt tatattttaa gtagattaga tattattttt tttaggaagt tttttttgat 73680 tgttttagtt ggatagaggt tttttttttt tgtgtttttt taatgtttaa taggtattta 73740 ttgagtattt gtgatatgta aggtatttat aatataagtt agtgtttttt gtttttttag 73800 agggtatatg aataaataaa tggtaagatt ttttaatatt tatttatgtt ttatagaaag 73860 ttatttatag gtatgggagg gttgttttaa ttgtgggtga tagggaggtt tttttaagat 73920 ggtagtgttt tagtaagatt tgaatgaggt ggttaggagg tttagggagg gattttttag 73980 gagggaataa gtgaatattt ttttgtgagg atgagttttt atgttttagg agtagttagg 74040 ttaggggatt ggtgtagtga ataggggttg aggggagtgg ttaggtgatg tagggtttta 74100 taggttgttt tatgatgagt tagtgtttta agtatagtag atatttaggg aaggtttagg 74160 ttggggagtg atttgaatag attttttatt taggagttta ttggggtttt tgggtttatg 74220 ttgttgtgtt attgtatgtt tttgggggtt tgggggggta ttttttatat tattattata 74280 ggtagtattt ttgggggagg tgtgttgtgt aggggatttg ttggttattt tgttgggtaa 74340 attatagggg attgtgtagg ataggtggtt agtttaggag ggataattat ttaagtaggg 74400 gttagagggt atttggattt gggaggagtg tttaattttt taggtttagg taattagagg 74460 tggggggtgg ggtgttgttt tttgatatgg gaggtttggg ggtttggttg tattttttgg 74520 tgtggaggtg ttgggaggtg tggaggtttt tttttgaggt tgggattttt tggttatttt 74580 gatttattgt tttgatttta ttttttagtt tgagggtatg gtttgaattt atagttgtat 74640 atattttttt ttgtataggg ttttgtgggg ttggtatagt agtttttttt ttatagatta 74700 ggatgtttag ttttaggagg gttgggattg tttaagattg tataattagg gttagatata 74760 gttgggttaa ttttgtgatt tttggtttta tgtatagatt ttaagtatat aggtaaaatt 74820 ttgttggttg ggagggttgg ggggtagatg agtggggggt agtttttttt tagtttttta 74880 atatgttagg tttttgggtg ggagggggta taaagatttt atttttttta agagatagag 74940 aaagaggtag tggagggttt ttttttggtt gaggttttag gttttgagtg gtgaatgtaa 75000 ttttatttgg aggttggaag ttaggtggtt ttgggggtgt gtgaggtttg ttagtttagt 75060 tgtagttttt tttatgtaag ggaatttttt ttaggtagtg tttttatgat tagagagggg 75120 gttaggaaga ggtgagggtt gtatttagag tgatatttgg gtgggtttta ttttggggat 75180 atggttatat tttttttttg gatttttgaa gtttttaggt gtgggttaag ggtttttagt 75240 tgtaggtagg agagggtttt atagttatag atttggggag tttagtttgt aaagtttaga 75300 ggtttttgga ggttgttggt ttggtttttt gtgtagttgg gtttttttgg gaggtttttt 75360 tttggtattt ttagttttta gtttgtatga ttttttatag ttgggtttat ttttttaggt 75420 ttgggttata tggtgtaggt tagtggggtt ttgggggagg gtagggtgtt aggaatagtt 75480 ttgggggtgg ggggattgga gtagagttta ttttggttgt ttgtttattt tgtatgaagg 75540 atgttagatt tttatatgtg gttatttgat tttgtttaat tatgtgtaag ttttggttat 75600 ttttatttta ttgatgggaa ttaaattggt taaggagaag tttagaattt gagtagagta 75660 ggggtttaag ttttttagga gttttaggta ttttttagtt tttttttttg agtattgagt 75720 ttatatattt agtgtttgga tgtttattta tttgggggtt tggtgattgt tagttagtat 75780 ggtttataaa gggtttttgt gtaataggtt ttatttgatt tttttaaaaa ttttttgagg 75840 taggataatg ttatttaatt tattttatag ataaagtaat tgagttataa aatggtttgt 75900 taaaagatat agaggtagaa agattaatag taaagagttt ttttgtgatt ttgattagta 75960 aggtttttag aaaaaagtaa gggattttga ggtttttata ggaatagagt tttggaggag 76020 aataagagtt tagttttatg ttatttttaa ggggtatttt gaaggttaag gtattgggtt 76080 taagtaggtt ggattgtgtt ttttgtattt tttttatttt ttgaagtttt ttttttttta 76140 tttaggtggg ttgtggaggt gtttataata tataatggaa tagttggtag gttattgggt 76200 tttttattga gttaaggggt ttgattagag gtttaaatag tggtatagaa attatgagtt 76260 ttgttgtaaa ttagtttagg ttttggagtt aagtagtttt gtgtttatag ttagggttag 76320 ttgtttttag ttgtgtggtt tgaggttagt tttttaattt ttttgtgttt tggtgttttt 76380 tttgtagtag taataggaat tgttttttat ggtgatagtg tagatatatt ttatgaagtg 76440 tataaagttt tgagtttagt gtttggagta tgttaggatg tagtaagtgg ttatttatga 76500 tttatgaaat attaataagg tgaggggtgg aatgatagtt tttttgtgtt gtttttaaaa 76560 tggaaataaa tttgtttagt gtttaaagta gtagaaagtg agttaaggat aggtttttag 76620 tgatatgttt tggtagagtg ttttttgttg gttttaggta gggtttaggg tgggtggtta 76680 ttttttagat gagtttattg ttggtatttg tttttagagt atatgtttgg attttttaga 76740 tttttttttt tttttttttg attttttttt attttgtaat ttttattttt tgttattttt 76800 ttatttattt ttttttttta tttttgttta aaaataaata atggaggtta aatgtgttag 76860 ttggtttttt ggaaaggttt ttttgtagta ggaatgtgat gggggtagtg gaggattgtt 76920 tagtgtaagt tatgtgattt ttgtgtggag ttggggaagg ggaggtgttg agattgaggg 76980 tgttaggatt gaggtattga gatggggtta ttggataatg gttagggtta gtttttgttt 77040 ttattttaat aggggttttt atatttaggg gttatatttt taaagttttt tggataagag 77100 agataaattt tattataggg ttagaaatgt tgtttttagg ttgttatttg ggtgggggtg 77160 agagatgttt tgttggtttt taaatattta ttttgtggat aaaattatta aggggaattt 77220 aatgttttta tagtagtttg gttaagatat aggtattagg ttgggtgtag tggtttatgt 77280 ttgtagtttt agtattttgg gaggttgagg tgggtggatt gtttgaggtt aggagtttga 77340 gattagtttg gttaatatgg tgaaatttta tttttattaa aaatataaaa attagttagg 77400 tgtggtggtg tgagtttgta gttttagtta tttaggaggt tgagatagga gaattgtttg 77460 aattttggag gtggaggttg ttatgagtgg atattatatt attgtatttt agtttggatg 77520 atagagtgag taagatagtt ttaagaaaaa aaaagatgta ggtattgttt tagggtttat 77580 aagtataatt tgatttttga tgttggtatt taattttgat gtagatttta gtaggaaaag 77640 ggagatgaat tagaaggttg tggggatgag gggtttatag tagtgtttat tagatttgtt 77700 ttggtaggta taagtgtttt ttggaggttg ttagataagt agagggttta ttttagagat 77760 tttggttttg gagggttggg ttagggttta ggaagttgta ttttggtagg gaatttagag 77820 ttattttgag ttttattttg gaagtaagag ttagggggta gaatagaatt ggaattaaaa 77880 gtttttgtgg gtttagtttt atggggatgg gtttggtttt atggggatgg atttttgtat 77940 tatttgaggt gattattagt ttggtttttt gggattagtt ttgagtgttt tttggggaaa 78000 gtgggatttg tagaggatgg ttttttagga tttgtttgat tatttatttt tagtttgttt 78060 ttattttagt ttttttgatt tttatttttt atttagaatt ttggagattt ggttttggag 78120 gtttagagat tagaaatgag gggagataag gggagaagtt ttttttttta tttgttggtt 78180 atgttaatgg gttgattttt taggaagtta tattagttat tgttattgtt ttggttgttt 78240 tgtttggttt tgaggttggg tgagtaagta ttttgttttg tttgtttttt tatttgagtt 78300 ttttgttgat gttatgagag gtttgattat gtgtttagga ggtataggat agagtttaga 78360 gttgtttaag aatatataag gttgaggttt gggttttgta tttgggaagg gttaggaagg 78420 gttaaaggaa aattttagtt gagtataatg gtttatgttt ggaattttag tattttggta 78480 ggttaaggta ggaggattat ttaagtttag gagttggagt ttagtttggg aaatatagta 78540 agattttatt tttataaaaa aaaattaaaa ttaaaaaatt aattaggtat ggtggtatat 78600 atttgtagtt ttagttattt ggtaggttga gatgggagga ttgttgagtt taggaggttg 78660 agattatagt gagtgggata ttgggttatt gaattttagt ttgggtgata gagagagatt 78720 gttttaaaaa aaatttttat attttatgga gtttagtaga atttttggtt agggtgtttt 78780 gattgtgaaa tgagtgtggt agttgttaat ttttgagggt gaagatttat ttattagtaa 78840 tttgtatttt ggtatggtga gaggaagtgt ttggggaaag atgttggttg aggtagagag 78900 tttagtttaa tttattgtgg aggagttatt ttagttttaa agagaaagat taataaattt 78960 taggtgaatg gtttaaaagt tatttttgta tatgtagagg gtgtattttg ggatatgtgg 79020 atattttttt ttaggatagg aagtaaaatt agtaggtaga gatgtgagtt tttttgtttt 79080 tgttggagtt aatttggagt ttttattttg gtttttaggg aagtatagat ttttattttt 79140 attgtagtta aaagattttt tgttgatttt tttagtagta tttagtttag ttttgtgggg 79200 agaggtggta gggggaggag atagagaaag atgagttttt ggtagttgtg attgggggga 79260 gagaaatgtg gttttaattt gtttttgttt attttataga tgggtggtgt tttattttaa 79320 aatttagggt agttgaggga ttgaaggaag agggggatat tttttaattg gggttttttt 79380 ttattttatt ttatggtgtt ttatatagga aagagttgga aggttttggg tttttggtat 79440 ttagttaaag ttttaggtag gggtttagat attgggttgt gttattattt taggtagttt 79500 gggagttagt gatggtagag ttttattttt attttgatta ttgtatagta ttttgttttt 79560 aggatagttt agtagttagg ttgttttagg gtttaaattt agatatttaa ttgtgggggt 79620 tttaggtaag tggttgaagt tttttgtgtt ttgatttttt aatttggaaa atgggatgat 79680 gaaagtaatt gttgggtagg gtaaggggta agtgaaagtt agtgtttgag agtgatgtgg 79740 ttaggattgt tgttgtgatt atatattgag tttttttttt ttatttgaga taagggtttt 79800 attgattgtt gttagaaaga tttagattta gaaggattag gaaagttgtt ttatttataa 79860 ttttagaggg aaggggaggt ttttgtgtta gttggttgtt gtaggggaga gggtgggaga 79920 tagatggggg atagaggagt aggggtagta ggaggaatgg ttggtaggga agtttgtttg 79980 agatttaaag gattgtttat taggaggata gtttaggttt tttttattga gaaagatttt 80040 tttggatagt tgggttgagg atttttaggt tttttgggtg gagtagaatt agttattatt 80100 gaagttatat aggtttgtaa gtataagtgg gggattgttt aggtattttt gttttatagg 80160 ggttaggtat taaggttagg gtggttagag gatatgatgt agtttagtag gggttttgta 80220 gaattattag ttaagaagat atatgtagaa gtatgtaagt gttttgagga ggtaaatttt 80280 ttgttggatt gaatatgggg agttgagttt ttaattattg agttgggttg tttggtttgt 80340 tttttttttt ttgaatagaa ggtttttaga tagagtagtt aggtaatagt atggttaagt 80400 aggggtttgt attttagttt tgttttgtag tttgattagg ttgttgtttt tttaggagat 80460 atgggattgg ttagggtttt tttaggttgt tataggaata aggtagggtt gtgatttttt 80520 ttatggttta ggtatttggg ggagggatta tgagttttag tttaggggat agataggaaa 80580 tggatagttt gttttttttt taattatgga gttggttttt tttttattgt atttttttta 80640 gttatgtttt ttattagaag attattgtat ttaatgggtg gttttgtagt gatatttagt 80700 ttaatgaagt tatttggtgg gggttttggg ggatgtagtt ttttgaaata tatatgggta 80760 gtgggtgagt tggaggttgt gtggggtttt gttttttggg gatggttagg aggtgtttta 80820 attatttgta atttgagttt atagtgattg ggatttgttg tttttttatt ttagtttttt 80880 tttattagta tttgttaagt gttagttagt aggtgttggt atggtttaag gtaggtttgt 80940 agttagatta gtattggggg agggattggg agagagattt ttagagtgga agttatagtt 81000 tttttttttt ttaggttggg taatagatta ttatttttag ttagttttgg ggaaggggga 81060 ggggttagtt gggttgtagg tatagtgttg gggttttttg aggtggttgt tgttgattat 81120 ggtttttttt ttttttgggt tgggtaatag attattattt ttggtttatt ttagggaagt 81180 gggaggggtt agttggggta taggtatagt gttggggttt ttgtggtggt tgttgttgat 81240 tatgggtttg ttattttttt tttagttggg ttgttatttt ggttttgaaa gtgttttttt 81300 tagtttttaa tttgtgttta ggaggtagtt gatattttaa gtgttgttat agtaggaggt 81360 tgggtttgta agtgtgattt gtttggggag gggtagaggg aaagattatt tttgtttaaa 81420 tagtggtttt tttttttttt ttgggggttt ttatagggtt tttagttttt ttttggttaa 81480 gaggtaagga gaggtaggaa agttttagga atattggtag agaagagata gggtaggttg 81540 ttagaggaag taggttgtag ggtgtttaag gttttaggtt gggttttggg aggttagggt 81600 atgggtaatt aggaggttta ggtagggaaa tttgttttgt agggattttg ggagataggg 81660 gagaggggat atgatagttg ttttttgttg ttttttggtt gtggttttta ggggttttag 81720 tttagattag aagtatttta tgtattgggt tttggtttag tttggaagta tggtttatag 81780 atttatatga ttatttgggt agtgattttt aaaaggtttt ttgttattag ttggggagtt 81840 tttgagggga gggtggtttt gtagagtatt tggagatatt aatgggttgt gaggaaagga 81900 ggaggtgtgg atatttttat ggttttaaga gaaaattaag gtagagttgg aggttgggtg 81960 tggtggttta tatttgtaat tttagtattt tgggaagttg aggtgggtag attatttgag 82020 gttaggagtt taagattagt ttggttaata tggtgaaaat tggtttttgt taaaaatata 82080 aaaattagtt tgttatggtg atatgtgttt gtagttttag ttatttagga ggttgaggta 82140 ggagaattgt ttgaatttag gaggtggaga ttgtagtgag ttaagatggt attattgtat 82200 tttagtttgg gtaatagagt aaaattttat tttaagaaaa aaaaagagta gagttggagg 82260 ttaggtggtt tttagagttt gataaggagg ttgtggggtt gggttgtttt tttggttatt 82320 tgaggggtag ggattggttt agtttgagtt ttagatttat aagaggttga attggagtgg 82380 gattttgaga tgaggtaggg ttattttgtt tatatttgtg tttaggtttt aatagttatt 82440 ttttttagga atttagtttg atggtttttt aggttgagag gttgttaagg ggttgtaagg 82500 tgttgtaatg tgtgagttgg tgggttttga tgtgtgatag tttggggtat tttttttatt 82560 gttagggaat aggaatgagg agttttttat ttttagtgtt tggtaggtag gaggttgtta 82620 ttggattgtg tgtttaggtg ttattagatt ttgagggttt atggatatgg tatatgattt 82680 ttaatgatta atgtttgtgt agtaggtgtt gaggtgtttt aattttgagt aaggttgggt 82740 ttttggaatt ttttttttgg taggaggatt tgtagttgag gaatttttaa gaaatttttt 82800 ggtagtaaat aaagtatggg gttggatggt ggatttatga gtgtttttat atgaatgtgg 82860 atatagatag aaaagatggt aaatatttgt gaataaaagg aatggttttt gtgtattgaa 82920 tttttattta ttggtttttg tttggtataa agtttttagg aattttttaa tagttttagt 82980 tagaaatgtg tttttgtttg gttatgtgga aaattttata tatattaaga tatatgatgt 83040 ttttggtttt ttttatgaat gttttatgtt ttttgggttt atgatttgga atttgtagat 83100 ttttgttgtt tttgttttag agttataagg attttggatg taggaaatat tttttatgtg 83160 taagggtttt tttttttttt gttagggttt attggttttt ttttgtttat aggtgttatt 83220 taaatttttg tatttgtggt tttttttttt taattatttt gtgtaatttg ttaatagttt 83280 ttttattttt agagtttggt tgttggagat atataaggta tatagaattt gtgaaatgat 83340 attgagtatt tattaggtat ttattgtgtg ttttgtttgg taataataag taaaattata 83400 atgttttggg tatatgagta tattttttta tgtttatttt tttagtaatt taatgagatg 83460 gttttataaa tggggaaatt gaggataggg aggttagatt ggtttaaagt tataggttag 83520 gaggggtagg gttaaaattt aaatttagat agtttggtat taaattttag ttttttatat 83580 gaaaggtatt ttgtaatttt ttgagaaggt tgggattatt atttttattg tatagatgag 83640 gaaattaaga tgttaaatgg ttagatagtt ttggagttag gaggtgggtt tagtggttta 83700 tgggagtata tggaatggag tttatgggag gtttgaggtt gggattttgt attttatttt 83760 ggtttaaggg atgaggtgat tgggagtgtt agagatattt tgggattggt tatttaggtg 83820 ttttgtattt agttttagtg ttgagtgggt gagggtggat aatttgttat ttagtagggt 83880 tgttgtttgt attttggtgg ttttttaaag tttggttaag taaagtaaga ttgtttttgg 83940 attagagtga tttttaagtt atataagtat ttagttatgt tttggaggat gtaggattgg 84000 gaaggttttt tttttattgt atttttattt agttttttta tggggtagtt ggttttaggt 84060 atagattaga tgtttttttt tttgtttgtt gttggtatgt ttttggtttt attgttgttt 84120 tagggagggg tttaagagtt ttttggtttt gttatttatt atattttgtt tagagggttg 84180 ggggtttagt attaatgtta agtatttagt agtaaaatta tgggttggaa agagttatag 84240 tgttgttttg atttggtttt attttatatt gggtgttgtt tttattagtt tttttttgtt 84300 tttggtttta ttttttaggt attataagtt ttgtaggttt aaagttaaat ttattagttt 84360 ttgatttttt ttagttggga ttagggtgag gtttttgttt aggtgtaaaa gttaaggtag 84420 tgttaaaaaa tttaggaatt aaataatatt ttgaagtaat attttaaata aattaaattt 84480 tatgttgaat aaattttgat agggttgtgt atgtgtaggg ttgggtttgt tttaatttaa 84540 aattttaata tttgtttatt atagagatta ttatgtatta ttttgatatt gaaaaatatt 84600 gtattaaata ttatttgtgt tgatttttga gttttttggt gtttttttat attttgtttt 84660 tgataagtgt ttgatatatt ttgttttagt tggttttgtt ttttaggtgt ttttttgggg 84720 ttgttttgtt tatgtttttt gtagttatta ggagttattg agttattgta tttgttttat 84780 tttgtttttt atgtttttgt attgtttatt ttgttatgtt ttttttgtgt gttttggttg 84840 tatgttagtt ttagatagga gtttggtggg ttgggagttt atattaatgt tgtttttttt 84900 tggttttggt gttgggtata gggtagtatt ggagattttt tttttttttt tttttttttt 84960 ttttttgaga tatagtttta ttttgttatt taggttggag tgtagtggtg taattttggt 85020 ttattgtaat ttttattttt taggtttaag ttttgttttt tggaattaag tagatttttt 85080 tgttttagtt tattgagtag ttgggattat aggtatatgt tattatattt agttaatttt 85140 tatattttta gtagagatgg ggttttgtta tgttggttag gttggttttg aatttttgat 85200 tttaggtgat ttgtttgttt taatttttta aagtgttggg attataggtg tgaggtatta 85260 tgtttggttg agattttttg aataaataaa tattattggt atggagattt gtttagggaa 85320 tttgtttaga ttttgttatt gtatttttgt ttgttgtgtt tagaggtaat ttagggttgt 85380 tttagttgtt tttatttggt tattttttgg tttttattta ggttggtttg ttttattttg 85440 tgggttaaga aaatgattta gtgggtggtg attagtattt tttttttaat ttgaaaagaa 85500 tatatttatt agtggtggta gtaatttaat gttttttagt tgatgaaggt aatatgtttg 85560 tttataatgg aatggtttat gttatggtgg aatattattt agggatgtat tggtatttgt 85620 tataatgtgg atggattttg gaaatatgat attaagtgga gaagttagat ataaaggtta 85680 aatgtgtaat tttttgtata agaaatgttt agaattggtt aggtgtagta gtttatgttt 85740 gtaattttag aattttggga ggttaaggta ggaggattat ttgagtttag gagtttaaga 85800 ttagtttggg taatatggtg aaattttatt tttataaaaa atataaaaat tagttgggta 85860 tggtggtata ggtttgtagt tttagttatt tgggaggtta tggtgggagg atggtttgag 85920 tttgggaggt ggaggttgta gtgagtagag attgagttat tgtattttag tttgggtgat 85980 agagtgagat tttattttaa aaaaaaaaaa aaaaaaaaaa agaatttata tagataggaa 86040 ggaaatatgg aggaggaggg taggattgat agttaaaggt tatggggttt ttttttaaga 86100 aaaaaatttt ttaaattttt taaattttta attttttaaa attggttgtg gtgatgatgg 86160 ttgtattatt ttttgaatag attgaaaatt atggaattat gtattttaaa tgggtggatt 86220 gggttatgtg gtgatttatg tttgtaattt tagtattttg ggaggttgag gtgggtggat 86280 tatttgaggt taggagtttg agattagttt taatatggag aaattttgtt tttattaaaa 86340 atataaaatt agttgggtgt agtggtatat gtttgtaatt ttagttattt gggaggttga 86400 ggtaggagaa ttggttgaat ttaggaggtg gaggttgtag ttagttgaga tggtgttatt 86460 gtattttagt ttaggtgata agagtgaaat tttgttttaa aaaaataaat aaataaataa 86520 attggtggat tgtatagtag tttatttgga ttttaataaa gttgtttaaa aaaaaatgaa 86580 aaaaagtttt tttttttttt aaaataaata aataaaaaga aaaaaagaga gaggggaaaa 86640 aaaaaaaaaa aaagaaaata ttgagtgtag tatatgtatg gtaaaggtaa gaattttatt 86700 atggaaattt ggttttatta atatatttta tttttatttt tattttatat ataggtgtgt 86760 tttggtttgt ggtgttaatt gtatgttttt ttggaggttg tagtttagat tggttttgaa 86820 agttgttttt tgggtaattt taaatttttt ataatttttg aagtttttgg tttgttggga 86880 ttatttagtt ttttagattt agttttgtta ttatttattt aagattgtag ttttggggag 86940 gggggttttt ttttaagggt gtaggggttt tgtggtttta ttttttttta gaatatatat 87000 tattttgtat tgtatatatg tgttttaata tggagtattt taggatgttg gttatagtta 87060 gttatgtttg tatattgatt gattgattgt gttttgttga ttaattatgt taattattgt 87120 gttgtatatt gtttttatta agtgagttaa agtaattttt ttggaataag ttgatggatt 87180 ttaaataagt taaaagatat ttttttagga aaaaaatagt aatgaatttt aagaagaaag 87240 aaaaattttt aaatttatag atttatggaa aaagtttaag tttttaaagt gttagatttt 87300 tttaaaagta ttaggtttag atggttttat gagtgaattt ttgaaaagtt ttaatagaga 87360 gattattatg ttgttgttta aaatgtttta gaaggtagag ggtaaaagaa atgtatttaa 87420 attgtttttg ttaagttagt ataatgtaga tattaaaatt gataaaaata gtatatatat 87480 atatatatat atatatatat atatatgttt tatttgtttt agattaagtt tgttgttgtg 87540 tatttaagta atattattta tttttatttt gttgttgaaa ttaaaatata ttttaatgga 87600 tttatgattt taatatgtaa aaatgaaatt atagaagtat tagaagaaaa tgtgggtgaa 87660 attttttttt ataattttag aatgtaggag atttttaaat aggatgtgaa ttttaaaagt 87720 taaaagggaa agtagagatt tgataatatt aggattaaaa tgttttgtgt agaagaatat 87780 tttagaaata aaattaaaag taggtagttg gggataagat atttgtattt gttgtgataa 87840 agatgtataa ataatttttt ttttttttta gataggattt tattttgtta tttaggttgg 87900 agtgtagtgg tatgattata gtttatagta gttttaaatt tttagattta aatgattttt 87960 ttatattagt tttttgagta gttgggatta taggtgtatt attttattta gttaattttt 88020 gtagagatgt ggttttgtta tgttgtttag gttggttttg aatttttaag tttaagtaat 88080 ttgtttattt tagtttttta aagtgttggg attataggtg ttagttatta tgtttggttt 88140 ataaagaatt ttttttaaaa aattttaata agaaaaggat atatttttta aatgaaaaga 88200 gaatataggg ttttggttta taatatatga agagataatt ttttttgttt gattgagatg 88260 tataaaataa aatattaatt ggagagtatt tggtttttag ttaggggtaa ggggtatagg 88320 atttttttgt tggattatta ttgtataggg tttagtagat agttgagtag gttgatgagg 88380 ggaggggttt taaaaaattt tagtaattat tttagaggtt aatttaggaa taaggattaa 88440 tttttttttt tttttttttt ttttgatagg gagttttgtt ttgttattta ggttggagtg 88500 taatggtatg attttggttt attgtaattt ttgtttgttg ggtttaagta agttttttgt 88560 tttagttttt tgagtaattg ggattatagg tataagttat tatgtttagt taatttttgt 88620 atttttagta gagatggggt tttattatgt tggttaggtt ggttttgaat ttttgatttt 88680 aagtgattag tttgttttgg ttttttaaag tgttgggatt ataggtgtga gttattgtgt 88740 ttagtagatt aaaatttaaa tgtatatatt tttgatatag aaatttatta agagtttatt 88800 ttttagttat gtgtgtatat gtataagtgt gagaatattt gttgtagttt tttaattata 88860 gtgggaagtt ggataagttt ggtagggtta tgggatagtt gatgatataa ttattaaaag 88920 gaatgtgtta ttttgggagg ttgaggtggg tggattttaa ggttaggagt ttaagagtag 88980 tttggttaat atggtgaaat tttgttttta ttaaaaatat aaaaattagt taggtgtggt 89040 ggtaagtatt tgtgatttta gttatttggg aggttgaggt aggagaattg tttgaaagtg 89100 gaaggtgaaa ggtggaggtt atagtgagtt atagtgagtt gagattgtat tattgtattt 89160 tagtttgggt tatgttttgt taaaaaaaaa aaaaaagaaa aagaaaaagg aatgtgttat 89220 atttataagt ggtaatagtg ttgttaaatg gaaaaaataa aagttggtag tagaagtttg 89280 attttttttg tgtttttgaa aagtttatat ttatatattg atttttttta tataagtttt 89340 gaatgatttt gtaggaataa aatttaggag aatgttatat ttagttgtta atatggttat 89400 tttttgggag agagttgggg aatgggagag aaaaattttt ttttaaattt tatgtgattt 89460 ttatttttta tttaagaatg attgggtatt gttttttttt ttttttttta gatgggagtt 89520 ttgttttgtt gtttaggttg gattgtattg gtataatttt agtttattgt aatttttgtt 89580 ttttgggttt aagtgatttt tttgttttag ttttttaagt agttgggatt ataggtgttt 89640 gttattatgt tttgttgtgt attgtttttt aggatgaaga aagggaaagg ttatagggag 89700 aatgggagtt agaatataga gtagggtttt taaatattag tttgtgggtg agagagatat 89760 ggggtgatat tattggtttg gaatttaggg atggtatgag gtgttgttta ggggttttag 89820 ataaggtttg tttgttgatt aagtaagggt tgtgttggtt tttgtttatg tgtttgttta 89880 atatgaattt tttaggtgtt ttattttgtt ttatgaatta ttattgttta ttttaattat 89940 gttgtatagg aagaattgtg tttattttta taatgagaaa atggattaga gaggaaagtt 90000 attaggtagg gtaggggtgg tagtttaggt agtgtgaggg taaagttggt gtttttttgt 90060 tattttttta tatatgagtg ggtaaggtat tataggagtt tatattttaa tttttgtggg 90120 ttattttgga aggtggtaga tggaattagt gatttttagg gttattttta gttttaggtt 90180 ttagataggg gttgtggagt ggaattgagt ttgatttagg tgtgttgatg gtagttatgt 90240 aattgtggat aaattatttt tttttttatt tgtattggat gagattggga atttttattt 90300 tgggtttttt aagagttttg gggttttata gagtatattt agtagtagta gtgggatggg 90360 gggatagggt taggggagtt ttatgttttt tttaatttta attagagtat ttttatttta 90420 attttttttt gggtttagtg tttagagaga atgggaagga agtttagttt tggttatggg 90480 ttattttagt ttgttagtta tagtttatat tttaggagtt ttttttggat tgaaggagat 90540 agagttattt ataatattta tagaaaattt tggagaggaa gtggagttta attgaggaag 90600 tgtttttttg tagtttttag aaatgaggtt ataggtgaga tagtgtgtta gggtggatta 90660 tatggtattt ttttaggttg tttgttggaa tttagggttt ggttaggggt tgtttatatt 90720 ttgggttttg aggtggggag tttgagtgtg tttttttagg gttgaatgtg ttttttgttt 90780 atattgtata gagtatggtt gtttggttgt ggtgtgtttt tttggatagg tttgttattg 90840 tgtagatttt taattttggt agttgttttg ggtttgggag gtggtgggta tagatatagt 90900 tttttttttt tttggtagtt gttttgattt tttgggataa gtgttgagag gtggttttat 90960 ttagtgttat gtgtttgggg gttggggttt tattttgggg ttaggttggg tggttagggt 91020 tatagagttg tagggggtgg agtagagaaa ttgtttttag tgtttgtttt ttggttttat 91080 ttttttttgt agttgtgttt tatttaaggt attttatagt tgtttggtat ttgttgtatt 91140 tttggattag tttttttttt tttttattat tgtatggtgt ttggtaggtt ggtgagggga 91200 ggggtttttt ttttgggttt tggagttagg ttttgttttt tggttttatt ttgttttatt 91260 atgaaggaga tatattgggt ttggttaatt tttttgtatt gatttttgtt tttttagtat 91320 atgtgggatt ttttatttta gatttaggtt tgagaggttt tagggatagt ttggagaagg 91380 agggtatttg tttttagaag gggaaagaga aagagattta attttaaagt aaaaggggat 91440 ttgggtgttt tttgtaagta gtttaggaaa atgggaggag gtgggagtag tgggattttt 91500 tgagtaaggt attttggtag gaatgttagt gttttttgga tatttttaga agtagaagta 91560 tatagtttta tagaaaaatt ttgtaggttt aggatttgag gtatgatatg atttaaattt 91620 attgttttat tagatattag tgagtttttt gatgtttatt aaggtttttt gttttatatt 91680 tggtattgga tgaatttgta tattttgttt tagggagttt atagtttagg gataggttta 91740 gagtttatgt ggggtgtttt gtaaatatgg ggttagaagt tgggttgttt atggggtttt 91800 ttttttttaa attatagtgg ttattttttt tttaatttta tagtttttga tttttattag 91860 gaatttttgg ggtttagtag gtgttttttt tttgtaggtt gatgtttgtt ttttttattt 91920 tttatttagg tttagttttg attttatttt ttttaaagtt atttttttat tgttttgtgt 91980 tgggtggttt tagggagttt tgtgttttga ttaattttat atttaatgtt gtattggtag 92040 ttttgttgtt tgtgttgaga tttttttttg ttttgttttt ggaatatatg gtttggtgtg 92100 gattaagtat gtgaagagtt atgtttatta ttattagttt gggggggttt gattttttgt 92160 ttttttaatg ttttatttat atgataaaga tttttagatt ttttgggtta taggaaaatt 92220 attgagatat gttgttatgt ttattttgtt ttaattttat atttatgttt ataagtggtt 92280 ttagaattat tgtggatttt ttttttggtt tttggggtgg gtggatatat gagagtttag 92340 tttttagtta tttttgtaga tgtttttttg atagattaag aaattgaggt tgggaggggt 92400 ggaatgatag tttagaatta gttgatttat ggggtagagt tgggatatgt ttagaattga 92460 gttgggtatt gggtttggtt ttttttttgt ttttagtgag tattttaaga aggtagagaa 92520 ttagatttat gaatgagtgt tgagtatttg ttttataagg tagttttgga gaaatttggt 92580 tggtgtggtt gaggagttgg aggggggtaa ttttggtggg gggggttttg agttagtagt 92640 tagtttttgt aggtttagta ttgggtgttg tagtttagtt ttattttatt ttatttagag 92700 gtatttatgt tggggggtag gaaaagagta gggatttagg agaggaggta aggttgtttt 92760 tatttagagt ttgagaggat tagggatgat tttaaaggat gagtgttttt ttgtgggagg 92820 atagtaagga gggtgttaag tttaggggta gggttagagt tttggaaatt gagaatttat 92880 tttattagta taaagtttag attttattag gttttggggt ggaggagtag gtagggatgt 92940 ttttgttttt tgtagtgttt tttttttttt tttttttttt taattattta ggtgtttata 93000 tttttttttg aaatgttgat tttttttaga atttttatat tgaagttaat atttatttat 93060 tgagtttttt agtataattt ttagaggaga gattaggtgt tttgggggta aagttgatta 93120 ggaaagtttt tgtttggttt ttagggatga tttatggggg ttattatatt tgtttataag 93180 aattataaaa aagttatttt aatttattat tagtggttta tttttttagt ataattttat 93240 ggtatattta ttatgtttaa gttatttatt tggtatttta tgggattttt tttttttttt 93300 tttttttttt tgagataggg ttttattttg ttttttaggt tggagtgtag tggtataatt 93360 ttagtttatt gtagttttaa ttttttatgt ttaggtggtt tttttatttt aattttttta 93420 gtagttggga ttataagtgt atgttattat gtttggttaa ttttttgtat tttttgtaaa 93480 gatagggttt ttttatgttg tttaggttag ttttaaattt ttgggtttaa gtaatttgtt 93540 tgttttggtt tttaaagtgt tggatttata ggtatgagtt attgtatttg gttttttatg 93600 ggatttttta taaaaattaa gataggttgg gtatggtggt atgattttag tattttggga 93660 ggttagggaa gttgaggtgg gtgggttatg aggttaggag tttgagatta gtttggttta 93720 tatggtgaaa ttttgttttt attaaaaata taaaagttag ttaggtgtgg tagtttatgt 93780 ttatagtttt agttatttgg gaggttgagg tagaagaatt gtttgaattt gggaggtaga 93840 ggttgtagta agttgagatt atgttattgt attttagttt gggtgataga gagagatttt 93900 attttaaaaa ataaaaaata aaaaaaaaat ataaaaaaaa ataaagataa tagttttatt 93960 tttagaattt agtgggggta tgaaaggaat tttgaagatt atatagtaaa attttaagta 94020 tggatattgt tggtttatag gtgaatttta ggtttttttt tatttttgta ttttttgtat 94080 tttaaagaaa gggtatttga ttatttttta tgatttgaaa aattattttt atatttaaaa 94140 aaaaaagttt agtagaggaa agaaagttta tatataaatt atttatattt taagttaaat 94200 atgaggtatt tggattaggt tttgagggat gtataggagt ttattaaggt agtgatgtaa 94260 agagaagtag aggttagggt ttaggaggtt agggtaaagg ggttgtgagg aaaggtgtga 94320 gagattaagg gaagattaaa gtaggagaag ttgggaagga gagaggtgtg agttgagtag 94380 gagagtgaat taattgtgga ggggtttatg gtgagtgagt agagaaggtt tagtatggga 94440 agagatttta gtagtgttgt gttttgggga agttagtttg ggagtaattt agttggggtt 94500 ttaggagatt ttgttttgta tttatagttt tggggtggag ataaattata gtatagatgt 94560 ttttttgtag gtagaagtta aggggttggg tgtttgttta gagggtatgg aatttttttt 94620 atgatttttt tttttatggt gttagttgga tttttggtgt ttgggggata gaggggttgt 94680 agagattggt tagagttgtg tatgttgggg tttagggaat ttttagttta gttttatatg 94740 gaggggtaga aggggatggg tttgaaggaa agatgggtag gaagttgagt tggagagaat 94800 tggatttgtg tttagaatgg ttgtgatata gagagggagg atggagaagt aagtaggtgg 94860 tgttttggag gaagaattag tggggtttag gtttgggttt tttgagaagt tatttttatt 94920 ggattttaag agtatttttt tattgggaag gttttgtttt tgtttgtttt tgtatttttt 94980 ttatttggat ttgtttaggt ttttaggatt gttagtttag tttatggatt tttttatgtg 95040 agttggattt ttatttgtat aggtttttgt ttgtgggtgg ttgggtttgg gatgttgatg 95100 gttttttttt atgttttggt tttaatgtgt atattttatt ttatggagaa agttattgtt 95160 tttttagagt gttaggtttt tggtagtttt gaatgttgtt gtttttatgt ggtttgtttt 95220 tttttttttt ttttggtttg atgaaattgt atttttattg ttggggaagt tttttggata 95280 ttttttgtgt tttagttatt ttgtttatgg tttggtgagt tttagaaagt agagtttgta 95340 ggttgtgttt ttgggtttgg tttttggtat agtttttggt ataatttagg ggttaaattg 95400 tgtttgtttt tggaggagaa tgtttttgta tatttttatg gatatttttt tatttgtttt 95460 ttagagttag gattatgttt ttgtgtattt agtattagtt attattgaga tttagatggt 95520 ttggtgataa ttgttttttt agttatattt tgtttgattt agttgagtgt gaatatatta 95580 atttaggatg ggggtgtatt tggtatgtta aataaaggtt ttgtattaat agaaggtagg 95640 ggaggaaata gttttttgtt attttgtaaa ttgtttatgt ttttggtttg atattatgtt 95700 attagtaatt attgttattg agtttgggtg gttggggtag ggtggttttt tagagttaag 95760 tttagagaga tgggagaggg aatatgggat ttgtatattg agggttggaa aggatttttt 95820 aaggtttatt agtttttggt tatttagtgt gttttgatgt tttttttgta ggaaatgtag 95880 agttttaggt tttagatttg ttaagataaa tgtgtatttt atatgtttat gaaagtatga 95940 ggagtattgg ttttttttta aatttatatt ttttttaggt tttatatttt tttagttttt 96000 aagtttattg attattggag aatttttatt taaaaagaaa aattaaaaag gggttgggtg 96060 gtttatgttt ataattttaa tattttggga ggttgaggta ggaggtttat ttgaatttag 96120 gagtttgaga ttagtttggg taatttagtg agaatttgtt tttataaaaa aaatttaaaa 96180 attagttagg tatggtggtg tgtaatttgt ggttttaggt atttgggagg ttgaggttgg 96240 ggaattattt gagtttaggg ggtagaggtt gtagtaagta gtgattatat tattgtatgt 96300 tagtttggag gatagagtaa gattttgttt taaaaaagtt aaagaaaagt taaagaagat 96360 ggaaagaggg atttagagag atgtggaagt aatttaaggg tttattgatg gaggaatagt 96420 tatataatat aagtgtattg tataatagaa tattatttag tttttgaaag gaaggaaatt 96480 ttgttttatg ttatagtatg atggatgaat ttttaggatg ttatgttgag tgaaatgagt 96540 tagatataaa atgggtagtt attgtatttt tttatatata taaggttttt agagtggtta 96600 aataaattta taataaagat agaaaataga atggtggttg ttagtagttg ggggaggggt 96660 atggggagtt tggtttaatg gggatggagt ttagtttggg aggatgaaaa gggtattgga 96720 gatggatagt ggtggtagtt gtgtaatatt gtgaatgtat tgaatgttgt tgaaatgtat 96780 attgtaaagt ggttaaaatt gtatattgta tgttgtgtat tttattatgg ttagaaataa 96840 gaagtagtag ttaaattaaa aatttagatt gtgttgtttg tttaatttaa agaaggttta 96900 ttgagtatta ttgagttttg attttgtgtt tagaattaga tttggttttt gaggggtttt 96960 taatttagtt ggtattttat tatagtttta tggagttatg atttttgttg gggttagggg 97020 gtatgttttt gagaagggat ttaattatgt tttatagttt ggtattttta aataggtttt 97080 gtgttttata ggattggtat taattttttg tttgtaagtt ttatgttagt atggttgtgg 97140 gtttgagttt ttttaggatg ttgttggagt tttatggttt tttttttttt gttagaaggg 97200 tatttttaaa taaaattgtg tgtagttatt atatagtttt ttggtttagg tatttttttt 97260 tagtgttttg agaattttgt tttgtaggtt aaggtgtttt ttatgttttt ttttttttgt 97320 tataattatt ttttttgggg gaggaggatt agattatggg ttttaatgta agttttagga 97380 ggtatatgtt tttttttttt tttttaagtt tttggttttt gttgggtata tttaggtagt 97440 ttgtaatttt ttaagtagga gttattagaa tgtgatagtt tttttagggg ttttaatttt 97500 attttgtttt atatttttgt atgagtttgt tttggttttt gtgtggtttt ttatttttta 97560 agttttttag gttttttagg gatatatagt agatagaggt tttagtaagg tttatggtga 97620 tttataaagg aggttttttg aaatttagaa aattttttta aatttttatt taagttttgt 97680 ttggggtatt ttggtatgtt tttattagat agagagagtt attttttttg agtttgtaga 97740 tttttatttt tatgtatttt ggtttttttg ggtttttagg gtagtatttt ttattttata 97800 tttagttttt ttttttaaga ttttgtggta aagttagtaa ttaggttttt tattattata 97860 gtatttaaga tttagtgttt tgtgatttat ttttttggtt ttggggtgta gttttagtta 97920 tagggggttg gggtttgggt tttagtttgt tttgtagttg agatataggg gtaggttttg 97980 aattttttaa ggtttgggtt gggttggggg tggtgggtgt tttagtaggt ttgggtattt 98040 ggatttttat ttttttgggg gttgtgttgg tggtaggggt agtgggtatt ttggggattt 98100 tggaggtagg gggttttatt ttttggtggg ttgatttttg gggtttgatg atggtgattt 98160 ttgttttttg aggggttggt tttggtgttt tgtggtttaa tattttggtt tttttgagtt 98220 tgaattggga tgggttgatg gttttggtgt tttttatttg tttggatgag atgttaatgg 98280 atagtttagt gtgttgggat attggtttgg ttgttttggg gtttgagagt tttatttttt 98340 gtagggatgt tttgggggag tgttggttta gggagtttat atggtgggtt gagggttttg 98400 agttttttat gtttaggttt tggaattttt gggtggagtt ggttatagtg gtttggagta 98460 ggggagtttg gattttttgg ggtggggtgg agttgggtgt tttgattttt ttgattttaa 98520 aagatttttt taaggttgaa aaataaagag aggggatgta attggtgaat ggatggttag 98580 ggaatatttt ggtatgtttt ttgttaagga gtagtagagg aaggtaggtg atgtggtggt 98640 gagggttggg ggtttttttt tgttttttat gttttagtaa gtggaaggga tagttttatt 98700 ttaggagaat tattatgagt tttggggtag agatgtaggt tggagtggga agatgttgtt 98760 tgttgtgttt tgttatggtt atggtgtaaa ttatatagtt ttttttttta gttatgttta 98820 tataggaatg ttttagtttt agagaagatt tttatttttt tttttttttt tttgagatgg 98880 agttttgttt tgttgttttg gttggagtgt agtggtattt tttgggttta agtgattttt 98940 ttattttagt ttttttagta gttgggatta taggtatggg ttattatgtt tggttaattt 99000 ttgtattttt agtagagatg gggttttatt atgttggtta gtttggtttt ggatttttga 99060 ttttaagtga tttatttgtt ttggtttttt aaagtgttgg gattataggt gtgtgttatt 99120 gtgtttggtt ttgatttttt ttttgttgtg gttgttttta ttttttttta tttttagtta 99180 aggtatatat tgggatatta ttagtaaata tatttttatt attagttata gtgggggata 99240 tgtttttaat aataagtgat tgtaattgta attaattaga attgtagtag gaataaaatt 99300 ttattaatga tattaagggt ggatattgga gtttttagtg ttggtgaggt gttgggttta 99360 ttgagtttat tatatttgta gttgtttaat tttgggatgt aaagaatatt agtattttta 99420 gtatagatgg ggaaagtggg gtatggggta gatatagagt tagattgtat attaggttga 99480 tattagagtt taaggtttta attatttggt tgtttggttt ttttagttta gtttatagga 99540 attaattttt ttagttatta gttttttttg tattttttta tttattatta taagtttgtg 99600 tagtgatgtt aattattagt ttttgttttg tagttatttt gtttttttat tagggtttgt 99660 ttttttggag gtagtgggga tggtatttgg gaagttgtta tttttatagt ttttataatt 99720 gtattttaaa tgagagttag ttgtttttgg ttattagggt tagagtaggg agggatttat 99780 atggtaggta tatttattag tttttttttt aggttagatt tatagtgtat ttttgtggag 99840 atttatagtg tttttttagt tgttttttgt tttattaggt tatagagttt gggttttatg 99900 ggattttatt attgtttttt ttgtttatag gaaaagggat gatagttggt ttttagtttt 99960 taataatagt gttttaggat taattttagt gttttttttt tatttgtttt ttttttttta 100020 aatgtattta ggtattgggg aggggaagag gaagtttaat tttttaattt tggttgtttt 100080 agttgttagt tttttgggta aggtattttt gtgggtgttt tttttaagtt ataggtattt 100140 tttttttttg gtggatatag atgaaatttt gggttattaa gtttaatttt tattagaagt 100200 tgggtaagga gttgtgtgga ttttagagaa tttttagttg ttataggttt tgttttagtt 100260 ttgttattgt tttagaggat atgggtttgg tgtggttaga gttgtttatt ttttaagaga 100320 gtagaaattt ggatttttat atgatatttt ttgattttta aatgttggta taaagtaaaa 100380 taagtttttt ttaaaatatt gagtagtttg gttgatgtgg tgaaatttta tttttattaa 100440 aaataaaaaa ttagttgggt atggtgatat ttgtttatag ttttagttat ttaggaggtt 100500 gaggtaggag aattgtttga atttgggagg tagaggttgt agagttgaga ttgtgttatt 100560 gtatttagtt tgattgatag agtgagattt tgtttttata aattaaaatt aaaaataaaa 100620 taaaatattg tagggttaaa taaaattaaa tttataggtt gtatttgttt atgggtttag 100680 ttatgatttt tagttgatta tgtggttgta gggtagtagg atattgagtt ttagagttag 100740 gggtgtgtta ggtgtgggtt tttgatatgg tgtttttttg tttttttgta ttttgtatgt 100800 aaattgttgg ttgtgttttg attttgtaga agttttaggg ttttaaggaa aggttgaatg 100860 tttattttta ttagttagaa agtttagggt ttaatgttta gaattgaatg taatgagatg 100920 ggtttattaa gtttattata tttatatttg tttaaatttg ggttgtaaag aatattatta 100980 ttgtttttgt atagatgggg aaagtgaagt atggggtaga tatagagtta gattgtatat 101040 tgggttgatg ttagaaagtg tagagtttaa tgtttgggtt tttgtgtggt ttttagggtt 101100 ttttgtggtt ttttgatttg ttttttgttt tttgagtatt gtttaaattg tttttatatg 101160 gtgtgttttt gttttatggg tgttgtagag taggggttgg tttttaggtg tttttagtat 101220 ttttttgtgt ggttaagttg gagaatagaa attagatagg agaaggtttt gttttaggtt 101280 taatttaaga aaataaatga ttttttttgg gagatttggt gaattttttt tttgggagtt 101340 tttttggagt tatttttatt atggttaatt tatgattgaa gatattgtat taaagtagag 101400 gttgttttgg tgtgagttta tgattgagtt tatggtgtgg atgtaatgat ttattttagt 101460 taggtttatg tgtataagtg gattatttta gaattggagt tggttttttt tttagggtat 101520 tttttttttt tttagttgtt tgtgtggttg gtgttttatt attttggtta tttgtgtaaa 101580 atgtatatgt gtgttggttt ttaattattt tttttttttt tttaatgttt ggtgtttttt 101640 tatggatggg tttttttttt tttattagtt ggtttttgtg tttattgttt ggttttatga 101700 tttttttggg tgttttggtt tagtattatt tttatgttta ttagttttta gtaagttttg 101760 agatagtagg ggttgtttta tttgtagggg ttattttatt attaggatgg tgttgtttaa 101820 aggtgagttt gttttagata atagttagga gattttatag tttttagaat tgtaagagaa 101880 tataattgtg tgttagaaga atagtgagaa taggaggtgt tttattttgg aggtgtttat 101940 tttttttagg agatgtttta ttttgggggt gtttattttt tttaaggaaa ttatgttttg 102000 gttggaatgt taagaaggtg atatttaaat gaagaggtgt ttattttggt ttatgttatt 102060 tttttaaatg agtatgttat tgtttttttt tttttttggg aatttttttt aaagttaagt 102120 ttattttagt tttttttttg gggagttggt tttttatata gtttatatta tttttttttt 102180 atgttatttt ggttatgtta tgattgttga gattggttat gaggggtgtg ttttggtttt 102240 ttgggaatag agttgaatgt tttttatttt atgatattat gtttttatta ggttttaggt 102300 gtttttagaa aatttattaa gttaggtgtg gtggtttatg tttgtaattt taatattttg 102360 ggaagttaag gtggatagat tgtttgagtt taggagttta agataaattt gggtaatatg 102420 gtaaagtttt gattttatta aataatataa aaattggtta ggggtggtgg tatatgtttg 102480 taattttagt tatttgagag gttgaggtga gaggattatt tgaggttagg agattaaggt 102540 tgtagtgagt tatgattata ttattatatt ttagtttgga tgatagagtg agattttgtt 102600 ttaaaaaaaa aaaataatta aaatttatta aatgttaggt gtggtggttt atgtttgtaa 102660 ttttagtatt ttgggaggtt aaggtaggtt taaggtaggt ggattatttg aggttaggag 102720 tttgaaatta gtttggttaa tatggtaaaa ttttgttttt attaaaaata taaaaaatta 102780 gttaggtatg ggggtgggtg tttgtaattt tagttatttg gaaggttgag gtagaagaat 102840 tatttaaatt tgggaggtag aggttgtagt gagtttagat tgtgttatag tattttagtt 102900 tgggtgataa agtaagattt tattttaaaa aaaaggttgg attataggat tataggatag 102960 gtataagttt tgagggagtt tttaaggagg agggatgtat tagattttta tttttatttt 103020 agtttgtgaa gatttatttt tgtttgaggt tttgtagagg gttgattagt gatttttaaa 103080 aagatatgtt taatatttaa ttttaagaat ttatgaatgt gattttattt ggaaaaaggg 103140 tttttgtaga tgtgattagg gattttggga tgagattatt ttggatttgg gatgggtttt 103200 aaatttagtg tttggtgttt ttataggaga aaggtagaag gggatttggg atataaagag 103260 atatggtggg gagggttatg tgatgagagt agagattgta gatgttgtta gagttaagga 103320 gtgtttgggt taatgtaagt tggaggaggt aaggaagggt tttttttttg agttgttgga 103380 gggagtgtgg ttttgttaat attttgatgt taaatttgtg gtttttagaa ttatgagtga 103440 attaattttt gttgggttat ttggttttta gtaatttgtt ttagtagttt taggatattt 103500 ataatgagat ttttgggaag atgaaatttt tggttgtata gtggtttagg gtgaggttag 103560 ttggtgtggt tatttatttt ttagtttagt tttaatttta ttataattat atttgataaa 103620 tggtttattg tgggttaatg gatatgtggt tattttagag ttgttatatt aggagtttag 103680 aggagtgaga gttgtttttt tttttttttt tggagttgta taaaaatttt agatggttgg 103740 agaagttatt ggaggaatta tattatttta gatttttgtt ttattgttgg gatatgtggt 103800 aatgaaataa gattattttt gttagggatg ttttatgggt aattgttttt ttatggagga 103860 tattgtgagt tgtatttagt tgggaaatat taggagatgt ttgttattag gttggtagaa 103920 tagggttttt tagtattttt ttttttatta gagttttaag attgtgtttt gggttttgta 103980 gttatatatg gttgtttttt tttttttaat gtgtaggttt tttgggaagt tttttgttat 104040 tatttttata gtggaattgg tataatttgt ttaggggtag taggtttttg ttattttata 104100 tgtttttatt ttttttgtgg agggagatgt agttaagggg tatttatatt tatttataga 104160 agtgagagtg tttgtgagtt tgttattttg tagattttag aattttgtat gtgattgtat 104220 agatttatag gtttaattgg gtagatttaa aggatttatg tagtagggag gagtattgga 104280 tagttttttt ttttgtttgt aaggagttaa tgtaattgaa ggatatagaa gaggttttta 104340 gttgagtatt ataattgtgg attgtgtata gtgttagaaa gatgtggagt taggttatgt 104400 tgggaggatt tttatgttgt tattggaagg taaagtagtg ttattttttt atttatagag 104460 taggaggttt ttatttttgt tagttatttt ttttatttgt gaatttaagt tttttaaagt 104520 tagattttaa ttttgtaagt ttttaaaagt ttttttgggt ttttttttta atttttattg 104580 attttaattt gttttaaaag tttgaagatt gtttatgtgt tttggtttat ttttgggaat 104640 ttattttaag gaaataatta gaagtataga aagatttatg tatgaggata tttgtattag 104700 tattaaattg ataaaatttg gaaatagttt gggtttttgt agatttttta aatttatatg 104760 ttaaaggttt gtattattat taaaattata tttttgaaga tgagaaatgt tgagaatatt 104820 aagtaaaaat agtaggatat aagatgtata taaagatttt aattttattt tatatatata 104880 tgtgtagttt gtatgtatat atatatttat atttgggtag aaaataatga tttttggatg 104940 gaatgaatgg tggtgggtgt tgtttattat atttttttgt tttttgagat gtttatatta 105000 tatggggatt atttagtatg tttagggaat aaaattattg atattgtttt tttttttttt 105060 tttttttgag atagttttgt tttgttgttt agattggagt gtagtggtgt aattttggtt 105120 tattgtaagt tttatttttt aggtttatgt tatttttttg ttttagtttt ttgagtagtt 105180 gggattatag gtgtttggtt attatgtttg gttaattttt ttgtattttt agtagagata 105240 tgattttatt gtgttagtta ggatggtttt aatttgttga ttttatgatt tgtttgtttt 105300 ggttttttaa agtgttgtga ttataggtgt gagttattgt atttggttaa tattgttttt 105360 aaaaaatata ttttggtatt ggttgggtat ggtggtttat atttataatt ttagtatttt 105420 gggaatttga ggttagagga ttgtttgagt taggagtttg agattagttt gggtaaatgg 105480 taagatttta tgttggaaaa ataaaattaa aaaaaaaaaa atatatatat atatagattt 105540 tgatgttaat aagttggagg gtgtgggtaa ttgtatgttg gtttattttt atttttattt 105600 ttggaaaaat attttatagt ttaggatggg tatagggttt tttttatttt taagtattta 105660 tggttttagt tgttatataa aaagaggtta tagtgggtta ttttttagat gtaaattttt 105720 ttttttaggt ttatggtggg gttgaaatag gagtagtttg gatttgggtt tatttagaga 105780 ggaatgtgtt gtataaggga ttattgttaa ggtttttgtt ttgattatag gttgtttggt 105840 aaattgtttt tagtttttga aattagatta agtatttttt ggtgtatata ttaggtttta 105900 gtttggggag ggaatattaa gtgagttata gagttttgtt ttagtttggg ataaatgtta 105960 tgtaaagaaa tggtagagtt taaggttaga ataattttat gtgtagttta gtttttgtag 106020 gagggagtaa tgtggttttt gtttagggta gggtggaatt ttaggtttag gttttaggaa 106080 tgttagtttt ggttaaattg ggtttttttt gagtagtagt aaagtaggtt ttgtttttga 106140 agaaatattg gttatttagg agttagggtt agggtttagg gaagttggat agatggtgtt 106200 aaggagtagg gaagtatttt tttgtatgtt attttgagtt tgtaggaaaa agttatggga 106260 aaattttatt tggtagataa ttttttataa tttttaggat ttatagagtg agtttagtag 106320 tatgtatgtt atgggtattt ttttgttttt atttttttgt gatattggat tttggtatag 106380 gtttttgatt tgtgtagggt ggggtgggta gttaggtagg gttttggtgt tggtagagtg 106440 gggtttagtt gtaaaggttt ttttattttt tatttattta ggatttgggg gatgaggttt 106500 aaaggtttgg tgtgttttta aggagtttaa ggattgtttt agggttggag ataggatgta 106560 tgggtttgta tagggattgt gttttttatt ttagggttga gagtaggaga attaaatagg 106620 agagtgatat aattatagtt tattttgagt tttagtgttt ttagtgttat ttgttgtagg 106680 aggtgatggg gtaataaggt gtttttgagg ttaggtgtgg tggtttatgt ttgtaatttt 106740 aatattttgg gaggttgagg tgggtggatt atttgaggtt aggagtttga gattagtttg 106800 attaaaatgg agaaatttta tttttattaa aaatataaaa atagttaggt gtggtggtgt 106860 atgtttgtaa ttttagttat ttgggaggtt gaggtagaat agtttgaatt taggaggtgg 106920 aggttgtggt gagttgagat tgtgttattg tattttattt tgggtaataa gagtgtaatt 106980 ttattttaaa taaaaataaa taaataaata aaaaataaga ttttttgggt gtaggtatgg 107040 tatgtggtag gggtgattgt tgttggtgta attattattt tttgggtgtg tgtttgtggg 107100 ggttgtgtat gttgaaatgt gtggttattt tgttggtgat taaggttgtt ttggttttat 107160 tgttattaat tatgtttatt gattttatat ggtttatttt tgtgttttta tttagagttt 107220 tttttagtgt ttaagttttt ggaaggttgg aaggagtgag tagtgtagtt tttggttaag 107280 aattgaagta taaaaatttt agttttttta tttaatttta ggtgggataa ggttgggggt 107340 atggtttgta gtttttttat gttgtttggt atgggggttg ggtagttatt tgtggttata 107400 atgagttggt gaggtatttt ttattggttg gattttttgt ttggtttatt tttatattta 107460 ggtatttttt ggtgtttttt tttattgaaa tttttgtttt aggatttgtt tttggaggga 107520 tataaattag ttttttagaa ttggtttggg ttgtttggtg gaggagggag gtggtttttg 107580 gggtaggtgg agtaggtttt ggatagggag gaggatatag ttggggtgat ggggaggggt 107640 gtgtttttag gaagtaaaat tgtttaaaag gaaaggttta aaaataggtg tagtgaagtt 107700 gagtggagtt tgtaaaggga agttaggaaa tagtagtgtt agtggagggt ggtttttagg 107760 ttttttatag agagttatat ttgtttaggg atagggataa tgtgaataga aggtaaagtt 107820 tatattaagg tggaggaggt gttttttttt tagagagttg tagttagata gtttaaattt 107880 gttaaaggtt tgggagggaa gaattagggt attattttat ttttagttta attttttttt 107940 tagttttttt tttttttgtt tttttaaggt taggtttggt tgggttatag tgttagtagt 108000 taagatttgt ttttagtgtt ggtttagttt gtaggaggtt agtttggtgg ttaaaggtta 108060 ttgattgttt aggtttattt gtatatgtgg tttaatgatt gaggtttggg atttggggtt 108120 attatttata gtatttttgg ataaggagga aaagaattat ttttattaat ttttggatgg 108180 aggtgtaggg agtgttaata gtatttttga aaattttaaa tgtattaggg gggttagtat 108240 ttagggaaga gttataggag gttattttga tggattttga tgattatttt tgtttaagtg 108300 ttaggaggag gttttttttt ttttgttttt ggtaattttg ggtttaagaa gttttaggta 108360 ttttggaggt tttttttgtt tattatagtt ttatttaaga ggtttggttt attttgtaat 108420 gatgatgtga gaatgagtag gtttgtttag tgttagagtt tgtggttgga tttttggttg 108480 aggttaagag aaataaataa gttttttttt tttttttgta tgttatagga agagtagttt 108540 gttggttgta aggggatttt ttattttgtt tatggggtat agtagtttat agtatttttt 108600 ttagaaatgg agtattggta ggtttgggtt tttgtaagat ggaatataaa ggggtgggta 108660 gttgatttta atagttagtt tttgggattt taaatttttt tttatttttt aattttgtga 108720 tgttaatttt tttttggata aagtttttta ataatttggt aagttagtat tagttgaatt 108780 agttttagtt tgaattagta gtttttttta gtttagttat agttttattt ttttagaagg 108840 gaaaagaagt tttatggatt tttttataag gaatttttag aatttgttat ggtgtttgta 108900 ggggatattg gtattaattt tgggtttatt aaatgtagtg ggtttaatag tgttttttaa 108960 aatgatatgt tttaagtttt aatttttgga atttgtgaat atgattatat ttggaaaatg 109020 gatttttgta gatgtaatta aggtaagggt tttaaggtga gattattttg aatttagtgg 109080 gttttaaatt taatggtgag tatttttata aaagatagaa aaggagaaag atatatagat 109140 agggggagaa agttatgtgg agataggggt tagagattag agatgatggt gatgtgtttg 109200 taggttaagg aatgttagga atttttagga gttgttggaa gttatgtttg taagttttta 109260 ggttgtggta ttttgttata gtaattttag gatatagatt ttaggaatag aatatagaaa 109320 agaaatggga ggaggtttag agtttgttgt ggttatttta gttattttat ttgatttttt 109380 tagtgttttg ttaattttga agtttttttt agttattgag ttattggttt tgaaaaggag 109440 atatgggtgt tttggagttg gtttagtttg gtaggaggta gttttgtttt attgtttttt 109500 tattagttat tagtttatat aggtttttta tagtgggtaa gtgtgttgtt gttttagttt 109560 ttgttggttt tttttttgtt tggttttatt agttgtagag ttttttgttg ttgttttttt 109620 tggtttaaga ggtttatata tttagttttt ttgggataaa tttagtttat atttgttgtt 109680 ttattgtagt tatttaaggg ttttttttat taatgtgttt tttaagggat agtaagttat 109740 atggttgttt tatttggggt tagaattgtg ttttattaga gtaaggtttt ggagtaatta 109800 tatttagggt tagggagtta tttgtttaag aatagaaatg tgtggttggg tgtggtggtt 109860 tatgtttgta attttagtat tttgggaggt agaggtgggt agattatgag gttaggagat 109920 tgagattatt ttggttaata tagtgaaatt ttgtttttat taaaaatata aaaaattagt 109980 tgggtgtggt ggtgggtgtt tgtagtttta gttatttggg aggttgaggt aggagaatgg 110040 tgtgaatttg ggaggtggag tttgtagtga gttgagattg tgttattgta ttttagtttg 110100 ggtgatagag tgagattttg ttttaaaaaa aaaaaaaaaa agtgaaatgt gtagtttttt 110160 ttttttttat ttttgaaata tgaaggggag gtgattgtag gttttttggg aaagattttt 110220 ttattttttt tttttttttt tttttttaag atggagtttt gttttgttgt ttaggttgtg 110280 gtgtagtggt gttatttttg tttattgtaa gttttgtttt ttgggtttat gttatttttt 110340 tgtttttgtt ttttgagtag ttgggattat gggtgtttgt ttgggatagt tatgtagtag 110400 tttttgtttt aagttatttt tttttatgta gagtagaatt aggattatag taaaggtttt 110460 agaggaggtt attgtttata gggttttggg tttttttttt gaaaggtagt ttagttttta 110520 agagggtaat agtgattgat ttgggatgaa ggtttttttg tgtttgtttt tgttatttat 110580 tgtgtgtttt tggttttggt agttataggg ttattttagg tggattttaa agtggtgtta 110640 agttgttgga tttttttttt tttttattaa attagttatg ggaatgggag tatttttggt 110700 atatttttag atgtgttgta ttggtttagt gtttttttta tttttgggtt ttaaattagt 110760 tgttggttgt tttattagga gtagattgag gggaaatggg tggaagttgt aggggaagag 110820 atgtgaggta gataaagagg aagaattttt tggttggggt ggggttgtta gggtttgggt 110880 gggagggttg tttatttttt gtttttggtg gaaggtagta gaagggtggg atggatttgt 110940 gtgggagggt ttaggtgtgg tttgtttggg ggtaggagag ggattagatg attttttagg 111000 tttttttggg ttaaagattt tttgataaat ggttgttgtt gaaggtagga gtgaggtttt 111060 gggaggtgat tgattttgaa aaattatagg ttgtagtttt gagggtttta aaggttaagt 111120 atggagtttt ttaaaatgag gtttttttta gttttaattt atttatgttt tttaggtggt 111180 tttagatatt ttgttagggt ttttttggta gttttttgtt tttgattttg gagatagaga 111240 aatgtgatgt tggtttttgg tttgtttata gtttttttgt ttttattata gggttgttag 111300 ttattttttt agtttattgt gtgttttttt ttttttttta tttttgattt tttaataata 111360 gtagattttt ttttaaatat ttttttgttt agattttggg ttttatgtat gttgttttta 111420 gaaatgtatt ttagtttttt gtgaggagtt agtaaggttg tttggtgttt ttttttatgg 111480 atgggaagtt ttgttgggga ttaggatttg gatttggaga ttttgaggag tgtgttggtt 111540 agtgtttgtt ttgaggtttg ggatagagtt gttaggtata ggtagtattg gtgtgagggt 111600 ttagtttttt ggataagttt ttttttgttt gtttttagat ttgttattgt atatataggt 111660 ggtgattatt tttgatttgt ttgggtagag aagttatttt tttttttttt tttgttttat 111720 tgtttattag gggaaatgtt ataagtattt aaaaaatgta aaaaaaaaaa aaaaaaaaaa 111780 aaagtgttta atattagggg ttatttggtt taggtggagt ttttattaat tatggggttt 111840 tttgtgttgt ggttttaagg tgggtagttg atggtttttg tttgagttaa tatgagttgt 111900 agtttaatta taggggatgg tgattttagg gagtagagtt taggttttgg ttatagttgt 111960 atttaggagt tagttgtttt ttagatttgt agagttaggg gagaggtttg gaggattggt 112020 attgaatgat atgatttaaa gtgtgttaag ttgggttgga ggtgatggta gagttatagt 112080 ggttatagag tttttatgtg aatttatatg gatttgtttg gtttaggttt tgttgaattt 112140 tagggtgagg aggatttggt ttttattttt aaagatatga agaggttgat aaagaagagt 112200 tataggtaaa agggggtggt gggtgtgttg tgtaggaggg gttgtaattg gatgtagaag 112260 attttagaag gggtaattag agagaggtag tatttttaga agatgggttg tttggttgtt 112320 ttaaatagtt tagggtgtga ttgaggggat ttttggattt agttggggtt ttttttgttt 112380 tgagataatg tattgggaaa ttttattaag tttatttaag aatttgaaaa gttttttgga 112440 aatttagtgg gtagggtggg tttttgggag gatttttggt atattgtgag agttagatat 112500 agtgaggggg ttttatattt ttgtttagaa gttttatggt agaggggtag aagtttaggg 112560 aggagtaggt gttgagatta gaggggttta taagagaggg gtttggggta gggggtagtt 112620 gttgagaagt ttaggaaatg gtgtttgttt ttggggaagt gaagttttgg gaatagggtt 112680 ggtgaagggg ggtgggaagg gggaggtggg ggtggagggt taggttagat taggtatttt 112740 ttttagtagt agatttatga gtttttggaa tttgtttata gaagtgataa gtgttttgtt 112800 tttagttttg tttatatatt tatttattaa gtgtggtagg gatagttgtt ttttattatt 112860 tattttggga tttggattta agtggaggtt tttggagggg tagatttagg ggaaagggtt 112920 tttttagaag tagttgttat ttagaggatt tgagatgaga attttattat gtttttatta 112980 gatagaggag atttgtggtg tttttgagtt tggtttttta ttttttattt agtagtgttt 113040 tttttgttta ttttaagttt agaatatttt gtttttttta agattagttg ttgtagtgga 113100 ttgaatagtg atttttaaaa gatatgttag agttttagtt tttggatttg tgaatgtgat 113160 aggagttgga atagggtttt tgtagatgta ataaaggatt ttaagaggag agtattttgg 113220 atttagggtg ggttttaaat gtaatgataa gtatttttat gagatataga gatatagaga 113280 aaaggttatg tgaagatgga gtagggagtg gtgtgatgta tttatatgtt taggagtatt 113340 tgggagttat tagaagttgg gagagaggtt tgggttggag ttttttgtag aggttttaaa 113400 ggattagttt ggttgatatt ttgattttgg atttttggtt tttagaatta tttttagttt 113460 ttaaagtttg tggggttttg ttgtagtagt tttagtaaat tgttatgggg gttttttttt 113520 tttgttaagt ttggtattta aagtttttta gttatttggg gttaattata ttgattttgg 113580 gatttttagg ttatttgtgt gttttatttt tttgtttaat ttttagtgtt tgtgtggtta 113640 tagttttttt tttgtgatat gagttttttg ggtttttgag tgtttatttg ttttgtattg 113700 aaggttgaag ttaaattttg gagagaattg attttttttg tgggtagggt aggtattgtg 113760 tttttagtat agttagaggg tattggttga aatgtgtttt tgtaaagtgt tttttttatg 113820 tttgtatttt ttttttaagt ggggaagtta gagaggtttt tttgattttt tttttagttt 113880 tttggggtag gaagtttgtg gttatttgtt tgtaaggatt aggtggatag ataattagtt 113940 ttttttaggt tatattttat taatagaggg ttttttaatt ttgttggtgg tttatgagag 114000 aaggaaaaat tgaaggagtt gtttatagta aattttaaat ttttgtgtta gagaggttta 114060 tggttgagta aggtattttt atttttattg ttttgagttg ttaatttagt ttagtttagt 114120 attgtgattt ttgatttgtt tgtgggttat gggagtttgg tttgttaatt agtatttttt 114180 agatatttat tttgtgaagt ttttagtggt tgagtgtttt tttgtttttt ttggatagtg 114240 tgggttatag gggatattgg gtaggaagat agttaagttt ttattgttta gaaattgttt 114300 gggtttattg tagtaatagg gatttattta ttagtatgag gtttttttgt aggaggggtg 114360 ggggtaggag ggagtttgtg gggtataggg ttgtaggagg agttattttt ttttttatta 114420 aattgtaggt tttagttaag ttatttttag tatggttgtt tgtgtgggaa gtttatagtt 114480 gagggattgt ttgtatgtgg tatgtaggag ttataagtgt tatttatatt ttattttggg 114540 ttaggtagat gatttttttg gttttagttt tttgatgagg aataggaagg gttggattga 114600 aagatttttt ttagtttgga tatggaatga ttttatgagg gttatggtga ggtttgtttt 114660 agttttgtat attagtttgg gttagtagtt tttaaaggta tagttgtagg ggttttggag 114720 tagggataag gaggattagt ttattttatt tttttgggta gaggttaagg attttgtttt 114780 tggtttatat tttttgtggt taaaaatgta gaagtaagta gtgttggtag aggtatttag 114840 atttttgggt aaagtagggg ttttatttga tattttaggt ttggagtatg agaaaattag 114900 tttaggtttt aggttttttg attgttagtg attagggaat gtgatatttt ttggtttttg 114960 tttttttatt ttttaatttt agggggagat taggttgggt gatgtgtttt tttttttgat 115020 agtaaatttt tatttatttt tatttttatt tttgttttaa gagggggttt tttatggttg 115080 ggtgtagtgg tttatgtttg taattttgga attttgggag gttgagatgg atggattatt 115140 tgaggatagg agtttgagat tagtttggtt aatatggtga aattttgttt ttattaaaaa 115200 atatgtgagt tggtaatttt aagtttttag tagtttttga atggaggttt tttttttgta 115260 ggatttttaa attttataaa tatgagtgtt tgtaatttag ttatttagga ggttgaggta 115320 tgagaattat ttgaatttgg gaggtagagg ttgtagtgaa ttaagaatgt gttattgtta 115380 ttttagtttg ggatatagtg aaattttgtt aaaaaaaaaa aaaaaaaaag gtgggggttt 115440 ttttatgttg tttaggttgg ttttaaattt ttgggtttaa ggaatttttt tgttttagtt 115500 ttttagagtg ttgggattat gggtatgagt ttatgaattt taaaaaataa tatttattgt 115560 tttgtttttg attgtaaaag gaatttaggt ataaagttga aaatttgtaa aatgtataaa 115620 aataaaggga aaaaatttat aaatttataa tttaggtaat ttttattaat attttgataa 115680 atgttttttt attttttatt ggggagtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg 115740 tgtgtgtgtg tttaaatagg tttatatagt gatgatgttg ggtgtttttt tttatgtggt 115800 gttatgtggt tgaggttttt atatattttg ggtttgtttt tttgattttt ttgtagtttt 115860 gatgttttga ttttagatat gttatttttg gtttggattg tttaggagaa ttatttttgg 115920 attttgttaa aaaatggatt gttggttttt aatttttggt ggttttggtt taggagggtt 115980 gggtaagttt gggtattttg gagtgttttt ggggtgttgt aggtgtgaat ttttgttttt 116040 ttgaagattt ataagtttta ttttttttat tttttttttt ttttttgaga attttataag 116100 aggaaagttt ttatttggag gttgttaggg atttggagtt gttagtttat agttttattt 116160 tgtttttatt tttttgggag ttatttaagg ataatgttta gttttagttg ttaagtttta 116220 gttttagggt tagttatata ttgaaggata tgtagaagtt gttgtgtgtt gggtattgtt 116280 gaggataaag gtttgaatga taagtgggaa taaagttata aggttttaaa atttgtttga 116340 ggttttatag ttagggtttt ggaaatttat gaaaaaagtt agtttaatat tttgttatgg 116400 aatataggta ggagagggag tagtttttag ttagttttta gttagttttt tgttagtttt 116460 tttgtgaatt attttatttt gggttatagt tagggtagtt gttgtttttt tttttgtttg 116520 atagtttttg agggtaggag ttagtttgtt tattattgtt ttttttttat tagggtttgg 116580 tattttgttt ggtatgtagt agaagtttaa gaagggttta ttgtgtttat tttgtaatag 116640 ttaatgtgta tgagtgttta ttatatttga agatagtgat ttatttttgt ttttattgta 116700 tagatgggaa attgaggtat tgagaggttg atgatttttt tatattgttg tgtgggtaag 116760 ggtaaggtta gatgtgagtt ggtatgttgg gttattgtgt tttttgttta tattttgttt 116820 tgggtttggg aaggttattt ttggagattt ttatgatgtt gatattttgt ttagtttttt 116880 tgtgtatttt tttttatgtt ttttagttat ttaaagtatt agttaggtag tattgttatt 116940 ttggttttgt aaatttagtt attgagtgga agagtagtta ggttgaagtg gggtagaggt 117000 agtttttgtt agattttagg gttgggattt ttagttattt ttatttttta aggattagta 117060 gatagagatt tttattgtgt ttagttaggg gttagggaat aggtttttat agtgggggag 117120 tgatggatgg atgtaggtgt ggattgggag gatttgggtt ggttttttag tgttggagtt 117180 ttagtagttt aatttatttt gttgggtttt tgtggggatt aaaagatatt ttgtatataa 117240 agtattagtt tagggtttgg tatttaggag gtgtttaatt aaaggaaatg gttatgaaaa 117300 ataataagga gaagtttagt tataggaggt gtttgtgggt aaggagagaa tagttggaag 117360 ggtttggatt tgggttagag ataaagaatg taagagggag ggagggagag aaggagggag 117420 ggagagaaag agggagggaa agaaagaggg agggagagag ggagggtagg gtaggtaata 117480 gttggtttta gggtagttgt gtgtaggagt ttgttttatt atttaaatat taggagagat 117540 gtaaatattt gagtgaggtt tttttagttt ggttttgttg tggttatagt tagggttgga 117600 gaaagagttt tttttttatt agggtttttg ttttgtgttt tttattttag ttgttttaag 117660 attttatgtt tttgggttag gagtaggggt ttgagagtag taattaggta gggtagtggg 117720 gttagggagg gattttgttt ttgtttttat tttttttttt tgtttttgtt tttatttttt 117780 tttttttgta tagtattggg tttgtaaagg tgtgaatgaa ggattttttt ttttatttga 117840 ttttaagggg tttaggtggt taagggtttt ttttgtagtt tagaaaaaaa agtaaagtag 117900 ttttttttga ggttttttgg tggaggttta gggtttaaag tttgttgtta taaatttgta 117960 gttttttttg tttttttaat agtgtttttt ttttatttgg gttattttat tattttggtt 118020 ttttttagtt ttttaggttt tttggggagg aggatagatg tagagtttgg attttgtgtg 118080 tagtagggtt tttttaatgt tgtggtgtat tttgtttggt tgtgggagtt tgttttatgt 118140 tatgatttgt gttggtatta atagtttttt tttttatttt ttatttgagt gttgagggta 118200 gttgtgttag gtatagatat atagtttttt atatatatta tgagtttgta gaaatggtaa 118260 gagaaggttg agtgtagtgg tttatatttg taattttagt attttgggaa gttaaggtgg 118320 gtggattatt tgaggtaagg agtttgagat tagtttggtt aataggatga aattttgttt 118380 ttattaaaaa tataaaaaat tagttgggtg tggtggtgtg tgtttggagt tttagttatt 118440 taggaggttg aggtaggaga attgtttgaa tttaggaggt ggaggatgta gtgagttgag 118500 attatgttat tgtattgtag tttgggtaat aagagtgaaa ttttgtttta aaaaaaaaga 118560 aagaaagaaa aagaaaaaaa gaaaaggaaa atggtaagag aagttggtta gtattatttg 118620 tttggtaaat ttttattttg gtttttggtt aggaagtttt tttttaggaa gtttttttgt 118680 tttatttttt tttttgagtt tatgtttaga tttttagtgt ttagaataga gttggttttt 118740 ggggtattta tggatggttg ttggataaat aaataagtta attgtttttt ttatttttag 118800 tgatgttttt ggtttggtag ggtatttagt agtaatgttt tttgagtgga ttttaaggag 118860 tattttttat tgtgtagttt gtattaggga ttttagtttt ttattttaaa ttaaaggaaa 118920 aaatttaatt ttagtaaata tatagagtat tttatttttt gatttttaat ggggggtaag 118980 aggtagagga tagaggagaa gattattttt ttaggtttgg tttggagtta aaaagatttg 119040 tatgttttta ttgtagataa tattggtttt tgggggatat agggtagggg tttggtttgt 119100 tttttgtagg gaaattgttt atttatgtgg aaagtggggt taagggtttt tgtttggaat 119160 tagttttttg tatatggggt ggggggtggg gatagaagga gattttgttt ggattgtatg 119220 gaaatttatt agattgttgg ttgttgattt ggtaggagta gagttatttt tattttttag 119280 ggttttgttt gggggagggg agaggttagg tggttttgtt taggttatat tttttatggt 119340 taggaatgtt ttttttttat tagaaagaaa gatgagatag gtttattttg aattttttgg 119400 atataggaag ggggtttatt tgtggtttag gtggtttttt tttttatatt taaggggttt 119460 tataaggagg tgttaggatt tttaggtttt gttttaggga attgttgttt gtaaaggtta 119520 taggtagaga tagttaggaa tgttttttat gttattggtt atgggttgga ggttgtgaaa 119580 ttaggtatag aattagaaag atttgttata ggttgtaaag ggttttagag agttttagtt 119640 ttttagaggg gtagtattgt agaaggggtg agaaggaaaa attagttttt aggaattgtt 119700 tatttagagt ttatataata tttaggtggt atgagataat ggtttatttt ttattttatt 119760 tttttgttgt tttttaagat ttgagttttt gggggtgttt ttagtagata gggggatgtg 119820 gggtaattgt ttttttttaa ttgtatattt ggaggtaatt tatatttaga tgattttttt 119880 gaggttgtga ttagagtttg gggtagggga ggggaagtgg gtggatggga aggtgaggga 119940 gattttttta ggaaagttgt tttaggtgtt tgtaaggttt tattgtttat atttaaggta 120000 taggtttttg gttttgagga tataggaaat ttgatgttat gtggggagga gggtattgta 120060 atgtatttaa ggttaggttt tttgattttt tggatattgg ataaatgatg gtttttttag 120120 ttggtttaga gatgttagga gtgatagaat gttaaaggtt gtagggggat atttagaaat 120180 ttttgagaaa gaagatggat aaggaaaaat aaaaaaatat gagaagttta gtagagtttg 120240 agttttgtat ttttggtttt ttttatggtt atgggtaatt ttttggagat ttagttatgg 120300 gagtagtgga ggtaggtatg ggtggggggg ggggtgggtt ttattgttta tggttttggt 120360 tgatattgag gttatttttt tgttttttta agtttttggg tattggtagg atttttaaaa 120420 atgataataa atttgaagtt tttagaattg tttgttggtt tagtttaaat ggagttttgg 120480 ggttttgtag attaaattaa atagtttgag tttagaaatg ttttaggtgt ttgggggtgt 120540 ttaggggtta attggtgggt ttgtttggtt ggagagatga taaatttttt tatttttggg 120600 attgtgtttt agagagtttt ggattttttg gttttataag taatttagag tttttaaatt 120660 tgggaaaaat taagagggtt ttggaaagaa aggtagtgtt tgattatttt tttttagtgg 120720 ttttgttaag ggagagtata ggaatttggt ttttggttgg gtttttggga tgaattaaaa 120780 taaaaagaaa aagttggggg agggggtggt ggaattgttt ggggttttag tttaggttat 120840 atattaagga gattttagag gagtaggtta gttttatttt tggtatgatg atggatgggt 120900 atttggttgg ttggtaaagg gaagagatgg taatagtgag gttttgaatt tagtggttaa 120960 gatttatttt tgagtgtgat tttttttgat gtttgggtat gtaagaaatg ggaggtggag 121020 aaaggaggag gagattttag ttttgttttt ttggtattag gttattaggg aatagtattt 121080 tttttttaat gggtaggtag aggttatagg ttgttaggtt gagaagtttt tggtttttat 121140 agataaatgt atagtttgta tatttgtatt attttgggtg atgtttatta tgtatggtta 121200 ttatgtatgt tttttattat taagatagtt gatgagatta ggtggttatt gtgtattggg 121260 tattgtggtg attgtttgat attgattttt gggggtttag gtttttggtg ggtttgtttt 121320 tttaggtatt tagttttttt tttatttttt gatattttgg gtttagtgta ggggtatggg 121380 ggtgtttagt ggatgggttt atgggttggg taagtagtat gtagttttgg tttattagtt 121440 tttggtttta ttattagata agatgagatt gttttagttg ttagtttagt tttgtattat 121500 atttgattgg gtttttgtag aggtttgttg gatgagaatg tttagggtag taggtattat 121560 tttttgggat gtatattttg ttataattgt tttttaggga aaggttagtt tgtagagttg 121620 aatgtaggtt gttagtgttt ttgttgtttt tatggtttgg ttatttagta agtgtttatt 121680 ttattgttag tgtttggttt tgtagatggg tatatggttt atttatttgt gatattttag 121740 ggtgggggtg ggggtagatg gtggtaggga agattaggat aattttttag taagaggaat 121800 ttgtagttaa tatgatgtta gtttttagaa tgttagttag gtaggaaaag gggggtttta 121860 tggttgtatt gggagtttga gtatttgttg ggtttagagg gatttttagg tgggtgttat 121920 tggtattagt gtttgttgtg ttttttataa ttagtggtga ttatgttgtt tggttttatt 121980 tatatagtgg tattatatag gtttttgttt gagatttttt atttttagat ttgtatattt 122040 aagtatttaa atttatttgt tttttgtaaa tgtttttttt ttttgtttag atgttatatt 122100 agttgtgata tttattatat ttgtaggagg taggatttgt gtttagtgtt atgggttgta 122160 ttttagagtt ttttagtaat ttttaaagag agttgttttt aattttattt tgtaggtagg 122220 gaaataggtg aagaaattga agaaattgaa gttgtttagt tttttaatgg tagagtgagg 122280 gtggtttggg tatttttata ttgttatatt ttttattttt ttaaagtatt gtttttttgg 122340 atgtaaattt tgtttattag ttttatttaa aatttttttg gatagttata gtttatagaa 122400 agtattttta gtttgtagtt atttagttat tgtaggggtg ttttggtgtt tatttttatt 122460 tgtttttttt tggatattta gtttagagaa tttatagttt tgttgtaagg ttgattatag 122520 tgtatttgtt gtttgggtgt tgtgtttgtt tttttttaaa tgaattaatt tgtagttggg 122580 atagtgggtt tgtttggttt tgggttttga atttaaagag tattaagtta gtgttgttag 122640 tggttgtggg atttgtgtaa gaggtttgtt tttatttttt atggtttttg ttttttatta 122700 taaaagttta aattgtagag aggtagtatt tataggatgt tttgagtttt ggttgaaagg 122760 tagggtttat tatgtaagag gtttattggt attaattagg gataggtttg tatttattat 122820 taagtaatgg ggtttttttt tttagagagg aaagaggtat ttgaattttg ttagtgtgtt 122880 agtttttatg ttttggaggt gttgggattt ttagataaga aggtatattt atatggtttt 122940 ttttatttag aagtttgttt tatagtttgt tttgttttta gaatatagat ttgggggttt 123000 tttttgggtg atagtggggg tttgggagaa gtttagatgt tatatagttt tgggatttga 123060 gtatgtgggt tttgggttag attgttttaa taaatattaa ggatttttgg attttttttt 123120 ggtgtgtaaa tttggttata gtaaatattg ttgagtaaag taggttaata gttggtattt 123180 ggaaaggttt ttgttatata aagatttgag ttgtaattgt gtttgtgata atagatttgg 123240 tttgaattta tgaaagtata tgttgtttgt tagttttgtg tttttattaa ttagaaggga 123300 gaaagaggaa agggttattt tttttgttat tttattatgg gtagtggtgg gtgttgtagt 123360 tgtttggagg tttgtttgta tagtggaaaa gtagaaaatg agattttaaa aattttatta 123420 gttaaatata aaatattttt tttgttgtta tgtggtggtt tttatagagt tttaaaattt 123480 tgaagtttgg agatttattt tgaaggggga gtaaaggtgg gatgtgggaa gtttgagttt 123540 atggaagata ttgatatttt ttttattttt gggaattttg agtttgaagg atttggtttg 123600 aatagtggaa ggattgaatt tttgtgtaat ttattggtga tggaatataa agttatggtg 123660 tttttggttt ttaagatggg agggatgggg aaggttttgg gtgaagggga taggtgggga 123720 aggaaaaggt gaagagaaag gtgtttttta gggagggggt agatgtgttt aggatatggg 123780 atattggtag aattttaatt ttgagtatat atataggttt atggatggtt ttttgtttat 123840 ttgtttttta tgggtgtgtt gtgttggttt gggtatttgt tttttttttt atgttaggtt 123900 atttgttgtt tattttgtat attgttatta gttttaagtt ttttagaata ttttgattag 123960 ggttttgtgg tttttgttat aggattttag gtttagatgt ttgtttgatt ggaaaattgt 124020 ttttagagat gttgtggttt agagtttgtt ttgttttggg gtggtttttg gagtttttgt 124080 tttttagtaa tttatatggt gataggtatt tatatttgtt ggttttagga attttggggt 124140 tattatttta gtgttgtaag gagttggtag tttttttttt atttttttgg tttattttgt 124200 aggaattaag atattaggtg agttgttttg ggaaagagat ttgtgttttt atggtgttgt 124260 ttttgtgttt atttttagtt attttagatg ttttttgtgg attagttgta tttttggtgg 124320 gtatgtttgg ttttttgtag tttggtttat atgattttta taggtaggtt tttttttatg 124380 ttttagtttt ttttttagtt agtttatttt agtttttttt attgttgttg gttgttgttg 124440 gttagaaggt tttttttttt tttgtaattt aatttttatt tttttttaag gtttgttttt 124500 tttatattga tttttttttt gttagttagt ggtgattttt ttttattttg atttggaagt 124560 tgtttgttta tattattttt ggttgggttg aattatattt ttttttttat tttttttaat 124620 tatttttttt ttatgtttgt ttgtttattt aaggttgttt aatttttata tatatatttt 124680 tatatttttt aattatattt taggtttttt gggtattagg gagggttatt tttttatatt 124740 ttaggttagt ttttatgtat atgtgtattt atgtatatat atattttttt atgtttattg 124800 atttgggtta tttgatggtt ttaagattag aatttttagt aaaattattt aggatatata 124860 agggggagat tgataaatat agggaattag tagattgagg ttttattttt tgagattgag 124920 aaattttttt ttagagttaa aggattgtta attgttgtat taggatggtt ttaatgagtt 124980 tattgttttg gattaaatta tagggttata aaattggttt gggagatagt tgtagaagta 125040 gttttagatg gaggtatatg ggggtaaggg tggagttata tttagagatt taaggaaggg 125100 gtattaataa tttttatagt gtaaatggtg atagttgtat aatgaatata attttaaatt 125160 ttggtttttt tttttgttat agggtttttg ttgagatatg agagtttttt tttagaaatt 125220 ttattggggg tttgatattt tttgttagga attgagagta gagattttga ttttgtaggt 125280 aggaggagag ttttgtataa tatagggttt ttttttataa gggtttattg gaaagtggtt 125340 agattggtta agttgtgtta tttggatatt tgggataagg aaggtttttg gaggagtggt 125400 tgtagggagg agttgtaaag aggtaggggt agggaggtta tatttatttg gggattgtag 125460 gaggtttaat ggaatatagt ggatttaggg agattttagt atgagtatgt gtttaaagat 125520 gtttagatga ggaggtgttg tgggggaggg gggtgggaat agtaagtttt tttagttttg 125580 tagatttaga tttttttttt ttttgggaag tagggatgta aagggataga gtttgaaaaa 125640 gggtttttat tattaagttg ataaagtaat tatgatgttt ttagtttata ttttgtatag 125700 tgttagtggt tattggatta taattttttt ttgttttttt gttgttttat atttttttta 125760 ggtttagttt tgaagaatag ttattggtat tttgtttggt gtttagttaa agttttggtt 125820 ttttaggagg ttttgttttt tttatttaga tagggttgat tttaggtggg ttgtgtgggt 125880 agttgggttt aggatattta gatgttagtt ttggttttgg ttatggagtg gggaggattt 125940 taggttggtt attttttagt ttggtttgat atttggatag tttgtttatt ttaatatagt 126000 tttttttttt tttggtttat tagagggttt tgtttaagtt agtttaggag tttttttgag 126060 gggtgggggt tttaggtttt ggtagaggta ggtttgtttt ttagaagttt tgttttagag 126120 tgttggagat tattgtgtga gttttttttt tgtttgttgt atttattttt gtggatgtag 126180 gatgtagagt tttagtattg gtagttaaga ggatgtagga aagtgtatgt atttataggt 126240 ttagagatgt ggatgttaga tttaggtttg gatagagtag ttttgtaagt tttaatatat 126300 tttgtaaatt ttgaagatag gagagagtta aaatattttt tttgtttgta tgtaggtttt 126360 ttttgttttt tatggtttga ttttgggagg tggatgagga tatttttagg tttggatggg 126420 ggttatggga tattttattt tagattttgt tatgatttgg gttgtgtttg tttggtgttt 126480 ttggtttatg ggttgtataa tttggtggtt ttgaaattgg tgtgggggag gggagggttg 126540 tttatttgag taggatgtgg ttgtttattt agttggaggt gaggaatgat ttttttattt 126600 tgttgttggg tttaagtggg gtttgagagt tgttggggag agttaaaggg aggggattga 126660 tggatttttt agagtgaaat tgtgtgtttt ggagagtttt gaggtagttt tgtgagtttt 126720 tgaggaggtt gttgttgttt ggtaaatata aataataata aaaggaagga aatttaggtg 126780 gtagtgtgta gaatgagtat agggttttgt gagggtgtgt agggtttatg tgggtgtttt 126840 taatagggtt ttttatgtag gtggtgtggg tatggggttg ggggtgtgtg gtgtttttag 126900 tgggagggtg tttggattag gggttttgtt tttttttagt gtatttttgt ttttttttag 126960 tgtatttttg ttttgtgtta ggtttatttg tagggttttt tttagtatgt ttgtggttgt 127020 agtagttagt ttagtattta tttttgaagt ttgaaatgat tttatttagt tgtgtgttga 127080 ttgtggggtt tgatatgatg gttggtgggt agtgggttgt gtggagggta gtggtgagga 127140 agtgtttttg gtggggtttg ggttttgtgt gttggttggg gtgttgtgtt tgtgtttttg 127200 tagtgtagag ttagttgttg gaggagtttt taggtttttt ggtttagttg aatgaatggg 127260 ggaggaaggt gggtgttggt ttttttttgt gtgttgtgtt tttgttttgt ttttgttttt 127320 tgggtggatt aggtttttgt atttgtattg gtttttttgt tttgtattgg ttgttttgtt 127380 tgtttgttaa ggttaggttt ggggggttgg ggtttgagtg gttgttgggg gatagttttg 127440 ggtatatgat tggagtgttt tttttttttt tgtttggttt gtgtttaggg gatggtgaga 127500 gatgtggttt tagttttttt ttttgggtgt tttgttgtgg ttagatgtgg gtggatgtgg 127560 aggttgggtt atggtgagga gggtgggtgt ttagagggga agagattttt tttttttttt 127620 gggtgtaggg tttttttgta ggaggttgta tttgggtagt taaataaagt tttttgttat 127680 tgttgttgtg tgttttgtgt ttgtaagggt taaatggtag tgtatgtggt tggtaggtag 127740 gattttggtt tgtgggttta agagttgagg ggtgtagggt gaatatgtga gttttatggt 127800 attagtgaga ggttattaat ttttatttat tgagggtatt tttgtagtta atatttttat 127860 tatgattatt gttttggggg ttattgttgt atttttttgg gtgagttttg gagaaggtat 127920 tgtttgggag aaggggtata gggtggggat ggaatatggt tgttagagaa gttagggatg 127980 ggtgatgttt tttttttttt ataataaggg ttttttgaga gtaggaagta gattttgtta 128040 ggagtagatg tttttgaagg aaggtgtgaa ggaaggagtt aggtagtgag tgagtagaaa 128100 gggagttgtt ttaagggttt tttttttttt tttgggtttt aatttgaggt ttagtttttt 128160 ttttaggtta gtggttttta tttttaaatt atattattta taaggtaggt agggttgagg 128220 ggttggggta gatttgggga tttgggttag atatagaatt tgagaagtaa taggttttta 128280 tttttaagaa gggtttttta ggtttgttat ttataagaga gagaggtgtt ttttttattt 128340 gttttggaaa gttagaaatt tatttttgta tgtttttttt gttattttgt tttttagatt 128400 tttggttttt gtttagagtt aggggttatg tgagaattta tagtatggaa taatattttt 128460 atttttgaag tagtaggttg taatgttata attgtatttt ggttttttga atgtgtggtt 128520 ggggagtgtt tgatagttta ttttgggttt gaggttgttt gttgtttatt tgtttttttt 128580 tatttttttt gaaatatttt aaatgtgtag gagtgttgag attttttagt tattttggag 128640 aggtgggggg tagggggttt tttgtggaaa atgttttagg tttgggtggt tttttaagta 128700 gatgaaatta agtttttttt ttttaagaaa agtaggtatt ttttttttta tgttttggat 128760 attttgaatt atttttaatt aagtgagttt gtggatatgg gaattgtaaa attatagata 128820 ttttagatgt gtgtatattt ttgttggttt gggagtttgg gttttagaaa tgtagttatt 128880 gttgttatta atagtatttt gtatttttta tgttaggtta gggtatgttt tgtttgaatt 128940 ttagtatttg ggtttattgg atagtttagt ttttattggg ttatttgttt atgttgtatt 129000 tggggatttg ggggtttagt atttaagaaa tttagtttaa taatatagtt tttttgggaa 129060 gatgttgggt ttggtataat agttatttta agttatagta ttatttttga gtgttttttt 129120 aaaaagtatt tggtgagtgt ggatatattt atgtaattgt ttttttttag ggttggtatg 129180 gagttttatt agattagtat agggttagtt aattgtatat tttttatttt tatgtatagt 129240 gtagtaaata tatttagttt tttggggagt gttgttaggg tgtatgtttt attaaaatgg 129300 gaatttaagg gataatggta ggagagtagt tagaaagtgt gtatgttttt gtgattgtgt 129360 ttagagttta ttggttttag ttttagttat tgttttttta atgtaattat ttagagttat 129420 atgattaggt ttagaaattt ttaggtaagg aggttttttg agttttttta ggaaatttaa 129480 attagggttt ggttatattt ttagttagga agtttatttt tgtatttaat taattgtttt 129540 aattgtatat tatttatttt tttttttttt ttgtttttag aggagatggg aaatagttgg 129600 gtattatttt ttaagttata attatttttt ttatatttaa ggataattta gttgtttttt 129660 ggtttttttt tttttagttt aaattatttt tttttagttt tttaattata ttttgagttg 129720 ttttttgatt atagttaagg gttgggttta gtttggggtt ttaggatttt aatgaggttt 129780 tattgttata ggatagtgag gaggtttttt attttttttt tttagggttt tagggtttgg 129840 atatatagtt ttagaagggg tattgggtag agaagatgta tgttggtagt agagaggaaa 129900 ttgagttgaa atttggtaag aataaaagaa ttataaaggt ttgtgtattt agtaaggtgt 129960 atttttttat ggttataaaa gaaggtaaga ttgattgtag gtttggttaa agggattgtt 130020 tgtgttttta gtgtataatg agatttatag tgggttggtg atttttttta aaataaagat 130080 atgtttattt ggaattttaa atgtgatttg attttgttta agggtttttg tagaaagaat 130140 ttaggtaagg attttaagat aaggtgggtt ttaaatttaa tgttgtgttt ttttaagaga 130200 tagaaaagaa agtatagaga tatagaaaaa ggttttgtga agatagaggt agagattgga 130260 gtgatgtagt tataggttaa ggaatatttg gggttattag aagttggaag aggtaaagaa 130320 aggttttttt ttggagtttt tagaggaagt tggttttgtt ggtattttga ttttagattt 130380 ttggttttta gaattgtgag aggatatatt ttttttgtta taagttattt agttttgata 130440 gttgttatag tagttaggag aaatttgtgt tttattttta tttgtattat gttttgaggt 130500 taaagtttta tatagtaaag atgtttaagt aattataaat tttgtgggta gtttatttgt 130560 ttagtagatt attgttttaa gggaaggggg atggggatag ggaagagagt tataggaaat 130620 ttttgtatgt ttttttggaa atgggaagga gtaggtttgg agagaaattt tataggttag 130680 gttttgggga aatgaagttt ataaagtgtg ggaatggagt ggggaggaaa tttatgagga 130740 agtagtgttt ggtgtatata tttatattta tgattttttt ttaggtatag tttttatgga 130800 gaggtttagt tggtagggaa gtaaaagagg tttggagagt gaaggaaggt gaggggtttt 130860 tttttagtaa tattgaggtt ttagatggga tattttatta ggtggtaggt tgtgttttta 130920 tagatagaga ttttttaagg gtagggttta gatggtttta tttttgtgtg gtttgatata 130980 aagtaggttt tttagagttg ttgagttttg ggtttgttag tggtagagtt ttttatagtt 131040 ttttaagttt ttatagtttt ttattttagg aaatggtgtt attatttatt tagttgttta 131100 agttaagttt ttgggtatta ttgttgattt tttttttttt tttattttta gtatttaaat 131160 tatggtgtgt ttttattttt agtttttttg tgaattagtt tgaatttttt ttttttagta 131220 gtgtgttagt taatggttaa taattggtta tttggggtta gtaaaagtaa taatatttag 131280 ttttttgatt tgtagtgttt gtttattttt gtggtgttaa tatttttgtt ttggttaatt 131340 tttttttttt tttttttttt ttgatagggt tttattttgt tatttggttt ggagtgtagt 131400 ggggtaattt tggtttattg taaattttat tttttaggtt taagtgattt ttttgtttta 131460 gttttttaag tagtttggat tataggtatt tgttattatt tttggttaat ttttgtattt 131520 ttattagaga tgaggattta ttttgttggt taggttggtt ttgaatttag atgatttgtt 131580 tgttttggtt ttttaaagtg ttgggattat aggtatgagt tattgtgttt agttggttaa 131640 ttttaagtta tttgtatgat attattggag gtgagattga gaagagatgt ttagttatta 131700 tgaatatagt gtttttatta tataaatata attttaagaa tataattgta ataggataga 131760 taatagttaa atgttgtaaa aaatttaaga ggtgatgaaa gttgtgtatt tattattttt 131820 tgttttaaat ataattattt ataagtaatt ttttaatgtt ttgtttaatt ttttttttat 131880 aatttgtaat ttaatttata ttgtaaaaat ttattatttt tttaatagag taatgtattt 131940 ttattgtgat aaaatatatg taatataaaa tttattattt ttggttagtt attatggttt 132000 atgtttgtaa ttttagtatt ttggaaggtt aaggtgggtg gattatttga ggttaggagt 132060 ttaagattag tttggttaat atggtgaaat tttgttttta ttaaaaatat aaaaattagt 132120 tgggtgtggt ggtaaatgtt tataatttta gttttttggg aggttgaggt atgagaattg 132180 tttgaatttg ggaggtggag gttatagtga gttaagatta tgttagtgta ttttagtttg 132240 ggtgatagag tgagattttg ttttaaaaaa aaaaaaaata aaaataaaaa agataaattt 132300 attattttaa ttaagttttt atgttagtga tattaagtat atttatattg tatatttatt 132360 aatattattt atttttgaaa ttttttttaa ttttttaaat tgaaattttg tttttattaa 132420 ataataattt tttatttttt ttttttttag ttgttggtaa ttgttatttt aattttttta 132480 tgaatttgat tttatataag tgaaattata taatatttgt ttttgtgaga taggtttatg 132540 tagtatgagg tttttaaggt ttattattta aggtttatat gtagtgatag aattttgttt 132600 tttttgaagg ttgaatgata ttttattgtg tgtatatata ttttgtatat ttattttttt 132660 tatatttgag taattgagag taaagttgtt ataaatatgg gtgtgtaaat atttgtttaa 132720 gtttttgttt ttattatttt attattatta ttttatttat tattagtatt attattattt 132780 tagatagttt tattttgttg tttgggttgt agtgtagtgg tgtgattttg gtttattgta 132840 atttttgttt tttagattgg agtaattttt ttgttttagt tttttgagta gttgggatta 132900 taggtatttg ttattatgtt tggttaattt ttgttttttt agtagagatg gggttttatt 132960 gtgttggtta gggtagtttt gaatttttgg ttttaagtga tttatttttt ttagtttttt 133020 aaagtgttgg gattatagat gtgagttatt gtgtttagtt attattttag ttttaaatat 133080 tatagtaatt tttttattgt tttatgagat tttttgagat agtggtttta gggattttat 133140 atatatttgt ttgattttgt gtaatgataa agtgtagttt tttttgtaga atggtagagt 133200 tgggagattt ttgatggggt atgagtttaa aggggtagag gggatgttta gaatatatat 133260 ggatttttta tgtgtgtttt gttagttatt aagtagattt gttttagttt tgatatgttt 133320 aggattatag atagtgtatg gtttttattt gggttaagtt tttggaattt tttttttttt 133380 tatattattt gtattgggag tagttattag gttgtggatt attaagtttt ttttaggtta 133440 tttgagtttg tattttttta tttagtttga ttgagttggt gtgtagttat tatattttat 133500 tatatttttt gtttggttgt tttaatgtaa ttataaggtt ttatttaaag aagtatatga 133560 ttaatttgtt ttttagattt tttagtgatt tttttagttt gttttgtgta gaatatttat 133620 agtaaaattt gattatagtg gtttgagttt ttatttttaa ggtaggggat tttttaaata 133680 aagtattagt gttttaaatt tatgattttt taaggaggtt tttggttttt agtatagtaa 133740 atgttttgtt ttatggtttt ttggtttttt atttttattt tatttgagtt ttttgttttg 133800 gtatttggga ttgaattagt ttggagtttt ttagttttgt tgtttgttgg ttttgatgat 133860 attattaggg attgtagtat tgtttggatt ttttgttgtt atattttatt gtaataatat 133920 ttaatttgat ggaattttgg gagtaagtgg taggggtagg gatggtggtg gttaggggtt 133980 gtatatatat aggatagaag gattgaagga ttgggtggaa agtatgattt ttttaagatg 134040 attttttttt agtagaattt tggttgtgtt ttttgaatag tatttgttta tttgtatatt 134100 tggtgagttt tgtgattagt aaatttagat gtttgggagg ttattagtgg ttttgttgag 134160 gtataattta gatatgatag tttatgtttt ttttttgatt tttttttttt tatatagttt 134220 tatgattaga gtgttttttt tatttttgtt tttattttag ttttgtaaga tatagttgtg 134280 aaatggttaa agtttttaat tttttagtat ttgtttgaga ttggagtata aaaatgagat 134340 ggggatatag tattttatgg atattagtga tggaaaaaaa ttttttgatt tttttgggag 134400 ttttgtaaag ttatattagg ggataagaag gagtggttag tttggtattg atttagtttt 134460 aaagtagtta gtgattaaag tatatagttg gtattttttt atttttaggg tattaggagg 134520 tttggttaga atttatgtta gttaggagaa ataggttgtt tttggggttt ttggtgtttt 134580 ggttttttta ttgttttttt gaagaaggta ttttgttttg tggggtttga ggttggaggt 134640 aatttgttat tgatgtagtg tagggatgag ggttgagtta ttagtttgtt ttagttttat 134700 gttagtagga ataataggga tttaagtaga gaagaaagta tttattttta aagttattat 134760 agtgattgag gtgatgtggt ttttagggag tttttttttt tgttggtttt ttgtggattg 134820 tggttttatg ttttaataat gtttttgttt attttgtaag gtttagtagg tggaaggaaa 134880 gagggtggag gttgggagtg gtggtttggt aatttgggaa gggtagggag taggaatatg 134940 tttttttttt tttgtatttg tttagaaggt tttatagggt ttgttttgtt atttataatt 135000 ttagggagat ttttttttaa tgtttgtttt ataaatgttt atttatttta tatttgaata 135060 tttttagtta tagggagttt agtatttatt tatgttattt attttatttt tggttgttta 135120 aaaaagagga aagagagaga aagaaaagat aggaaagata gagaaagggg gaaagagaga 135180 gagaggaaag aaagaaagag gaaagaataa gataggaagg aaagaaaaag gaagggaatg 135240 gaagggaagg aagagaggga agaaagagag aaagagagag aaagaggtat aaataaggta 135300 ggttttatgg agtagagatt taataaggga gtaaaatata tttgtagtta ggttgtagat 135360 ggatttttat aggagtgtat atttatttta ttttttttgg aatagaaaag tggaaagaag 135420 atgtagtggt gtgggtgggt ggtggttttt tttgggggtt tggaatgtgg ggtattagtt 135480 tttttggttt tgagaaggag attaagatta ttaatattta tagtggagat tgaattatat 135540 aagggttggg gatattgttt tttttgtatt tttaataaag atttgatgtt ttaattatgg 135600 gaatttgtgg aagaagaaat aaaattggtt ttggggtttt ttagagaatt ggttttttat 135660 ttagtggtgg ttgtgaagaa atttttggag ttagttttag tggtttgggt ttgtatagtt 135720 gagattgttt ttggaagttg agtggaagtg gggagttttt aggtatagtt gggttttgtt 135780 ttttatttta gttagtagtt ttaggatttt tgggtgtttt agagtttttt ttagagggta 135840 aatttagagt atgagggagt ggggagatgt ttaatattgg gggatttttg tttgtttttg 135900 tttttagttt tgttgatttg aatagggagg ttatgggtgt ttaggggtag aattgtgggt 135960 tggtaagttt ttagttttgg tttttttttg tttttttttt tttattgtta ttgattattt 136020 ttggttatat gttgatattt ttataggatg atggagaaga gagaagagga atttttttgt 136080 tttgtttagt atattttaaa gaggttttag tgtaaaggta ttgatgttta tagttaaatg 136140 tgtgtggggg ttttttagga gtgggatgtt tttattttgt tttagattgt tatgaattga 136200 tagaaggttt tatgttatta aatatatttt attaataaat tattttaata tttagtaaaa 136260 aaataaataa aaatgtatgt attttgtgtt ttgtagtgtt tttatgttgt attttttttt 136320 gtatttgagt tttggtttgt gtttttggtt tgttgttttg ggaatagaat gttttgtgtg 136380 ggaggtagat aggaagtgtg gggtgtgttg gttgggtttt tttagataat ttggtattgt 136440 tttttttaga taatgaaatt ttttttattt tgagtgtttt tggaagttag ttggtagtta 136500 gattaattta aatgaattat ttgttttttt tgtgaagtga ttttagggat ttaatgggtt 136560 tgttattaat atagtttttt ttgtattttg tttttttttt ttattttttt ttttttgtat 136620 gagttattgg ttatgatgat ttggtttagt taagggattt ggttagtttt ggttaggtta 136680 tgtgagagat agtataaagg attaaggttg ttggaattag gttagaggtt gagggttata 136740 tggatttttt ggagtgtttg taattgggga tttttaaggt tgttttttgg ttttggggat 136800 ttgtttattt ggggatagtt ttaagggaga tttttaaaag tagggagtta aaagggtgaa 136860 ttaatataga aatattgagg gttagggaga atttgaagat gggtttggtt gggtatagtg 136920 gtttatgttt gtaattttag tattttggga ggttaaggtg ggtggattat ttgaggttag 136980 gaatttgaga ttagtttggt taatatggtg aaatattatt tttattaaaa atataaaaat 137040 tagttgggtg tggtggtagg tgtttgtaat tttagttatt taggaggttg aggtaggagg 137100 attgtttgaa tgtaggaggt agaggtggta gtgagttaag attatattat tgtattttag 137160 tttgggtaat agagtgagat tttattttaa aaaaaaaaaa aaaaaaaaaa aaaagatagg 137220 tttaaggttt ggagagttag aagttatttt tttatttttg ggtggtttat tttgagattg 137280 tattatgtta gagaaagttg tgggagtgtt tgtttataat ttataagtaa tattgttttt 137340 tttttttatt agtttttggt tttagtaggt ttttgatttg tgtttttttt agggttttgg 137400 gtttttttaa gttggatttt tggttgttgg tgggatgatt atgtgatttg ttattttttt 137460 gtttattgtt ttgggtagtt tttgttattt ggtgtatata gagtggagtt tagtaaggtt 137520 ggggttgttg attttttgtt agttatattt gttttttttt atgttatttt tttttgtttt 137580 ggttatgttt aggggtttat atttttttat aagttaggtg ttagattttt gtgtttgttt 137640 tattttgttt tttttgtttg gtgggttttt tatatttttt ttggtttgat ttaggtttga 137700 tttgttttta ggttttagtt tagaggttgt tttttttagg aagttttttt gggattgtta 137760 gatgaaggga tttttttttg gatttttttt ttatttttat agttttagga atagttttta 137820 atttaggttt tattgagtta gtgtggtatt taggagagtt ataagtgtgt gatgaatgtg 137880 ttgaagtttt tttaaaagtt gaaggagttt tgtgaatata tagtagtatt agtttagatt 137940 gtgaaggtat aggggagtta gtttttttta gttttgtttg tttttggttt tttttttgag 138000 gaggtgggag ttagttagtt gggattagga ggtgggtttt atggagtaga gatttaataa 138060 gggaataaaa taaattagag aatttttttg ttgtaaggaa tttagataag gagtatttag 138120 ttagaggagg aaggaagaga ttggtagtag attttttttg ttttagtagt tttgtaagtt 138180 agatgggtta attttttagt atagttgttt tttagtatag agaaattttt tatttttagt 138240 aatagggtgg gaatattttt agatagggtt atggttattt tggttatagg gattatggag 138300 tttgagtttt tgtggtttgt tttatttatg tggttataga ttttgagtat atatttggag 138360 ttatagagtt taaagggtag ggtagggtag ggaatttgtt tgattggtga aggttatttt 138420 attatttgga gtataggttt ttgtttttaa atttatatgg agtttttgat atggggtatt 138480 gattttaagg aggtgaatgt ggatatttaa ggttagtgaa tggttaggtg ttaatatatt 138540 gataggtttt tggttttttt tttaatattg agggtaggaa ataaatgggg tttatatggt 138600 gtatatggtt tttagagtta gtaaggtgtg taagatttgg tagttgagaa aattgattat 138660 ttggttgggt gtggtggttt atgtttgtaa ttttagtatt ttgggaggtt gaggtgggtg 138720 gattatgagg ttaagagatt gagattattt tggttaatat ggtgaaattt tgtttttatt 138780 aaaaatataa aaaattagtt ggatgtggtg gtaggtgttt gtagttttag ttattttgga 138840 ggttgaggtg ggagaatggt gtgaatttgg gaggtggagt ttgtagtgag ttgagatagt 138900 gttattgtat tttagtttgg gtgaaagagt gagattttat tttaaaaaaa aaaagaaaag 138960 aaaagaaaag aaaattgatt atttgattat gaataagtta gaatatttat ttagaaaaaa 139020 aaaatagttt tgtttaattg gggatttaaa attttaggat ttatgttttt tttttataga 139080 gttatattat ttttttaatg tttatttttg attttatttg tttgttaagt tttaggtatt 139140 tagaatatag tatgatagta agttttgtga tttttatagg tttttttaat ttattttagg 139200 tatagttata tttttagttt tgagtagtag ggagtgatat gtagatggtt atttagatag 139260 agaaagattt ttaaaaggag ggtaggtttt gttttgtagg tagtatttat tgatatagat 139320 attagtaggt aaatttttta ggaagatttt tattaagaaa gaatgaaaga ggtttagtgt 139380 ggtggtttat gtttgtaatt ttagtatttt gggaggttaa ggtgggtgga ttattttagg 139440 taaggagttt gatattagtt tggttaatgt ggtgaaattt tatttttatt aaaaatataa 139500 aatttagttg gatgtggtgg tgggtatttg taattttagt tatttgggag gttgaggtag 139560 gagaattatt tgattttagg aggtagaggt tgtagtgagt taggattata ttattgtatt 139620 ttagtttggg gggtaataga gagagatttt gttttaaaaa aaaaaaaaaa aaaaaaaagg 139680 atgaaagata aataaggttg aaattggtag gttggtatat ttttaataat ttattttagg 139740 ttgggtgtag tggtataatg ttagtatttt gggaggttga ggagggtaga ttgtgaggtt 139800 aggagattga gattattttg gttaatatgg tgaaattttg tttttattaa aaatataaaa 139860 aattagttgg gtgtggtggt gggtgtttgt agttttagtt attttggaag tttaggtagg 139920 agaatggtgt gaattaggga ggtggagttt gtagtgagtg gagattgtat tattttatgt 139980 tagtttgggt gatagagtga gattttgttt taaaaaaaaa aagaaataaa aaataaaaat 140040 aataaaaaaa aaataattta ttttagtagg gagtaggagg taaggtttga tatgtagtgt 140100 ttgttaattt ttgtggtgta aatatattta ttgtggtaaa ttttaagtta taaataggat 140160 attattaaat atagagttgg gaaaagatat gtatattatt ggataaaatg tttaggtagt 140220 tatggtttat ttttttttgg gaaggggggt atgtttagaa tgttttttat tatggagaat 140280 gattgtggta aatagggttt aattggtagg ttgatttaat taattgttta ttgatgtgat 140340 gtggggtagg tttttgaggt tgtttttatg tttagggaag aaggtggtta tgtggttata 140400 gatttggttt tgggtttgtt tttttttttt ttttttgaga tagagttttg tttttttttt 140460 ttaggttgga gtgtaatggt gtgattttgg tttattgtaa tttttgtttt ttgggtttaa 140520 gtaatttttt tgttttagtt ttttaagtag ttgggattat aggtgtttat tattatgttt 140580 agttaatttt gtatttgtag tatagatggg gttgttggtt aggttagttt taaatttttg 140640 attttaggtg atttatttat tttggttttt taaagtgtta ggattatagg tatgagttat 140700 tgtgtttatt tgggtttgtt attttgagga tatatttgga gttatgtgtt tatgattttt 140760 tttttatttt aaaattttga ttttatttta ttgtttttag agataggttt tgttttgtta 140820 tttaggttgg agtgtagtgg tgtaattata gtttattgta gttttgaatt tttaggttta 140880 agtgattttt ttattttagt tttttgagta gttggggttg ggtttatagg tgttattata 140940 tttagttata ttttatattt ttttgtagag atagggtttt gtaatttgtt taaattggtt 141000 ttaaattttt ggttttaagt aattttttta tttttagttt tataaagtgt tgggattata 141060 gatgttagtt agtgtattta gtagttatta tgattgattg gtgatgtttg ttttagtttt 141120 aggatgaaag agtagtagta ttttagttaa gtatttgtgg tttttgattg gaagatgttt 141180 tttttgtttt ttaagtatag tgtaaatgtt atttttttgg taagtttttt tttaatttta 141240 tttttttttt ggtatagggt ttgttatagt tttgtttata taaagagagt tattagtgta 141300 tgtggtatag atgttagttg tttttttaat atttgagttt tttttttttt atagtaattg 141360 aagttttggt tgtgtatagg gaagtttagt tgaagaatat attgtttagt ttttttgatg 141420 ataggagtgg ttatataatt gggttttggt tagtgggaag gagttgaagt gtttaatttt 141480 taggttatgt ttttaaaaat aaagagggat atttgttttt tttttttttt tttttttttt 141540 tttttttggt tggagtgtag atatgatggt aggagttgga attattttag tttaagagat 141600 ggaagttgtg tgttgaggat gtattaaagg aatgaattag gtttgggttg ttttgggttt 141660 ttataatgat tgatatttgg attgggatgt gggtttgagt gttgtttagt ttttgatgtt 141720 ttagtttttg ttatatagtt agatggtgtt ttgattaatt taaggtatgg ttattatttt 141780 atttgtttgg tagggtaggg gttttatttt tatatgttga gtttttggta gaatttggtg 141840 taatatatat agttaaagta aaatgaatag gttattttaa ttaaggttta ttttgtgggt 141900 tggttttggt atttggtttt aatttttatt ttattttatt tatttattat ttttgagata 141960 gagttttata tttgttgttt agtttagaga ggagtggtgt gattttggtt tattgtaatt 142020 tttatttttt aggtttaagt gatttttgtg ttttagtagt tgggtagttg ggtttttttt 142080 gagtagttgg gattataggt gtatgttatt atgtttggtt aatttttgta ttttttgtag 142140 agatggggtt ttattatgtt ggttaggttg gttttgaatt tttgatttta agtgatttat 142200 ttgttttggt tttttaaagt gttgggatta taggtatgag ttattgtgtt tagttagttt 142260 tggtatttgg aattggaaaa taatagtttg agttttagag gggataaata taaatatgag 142320 gtagaaggaa tagtaagtaa atatgtgttt agagtaggtt gggttgttta tatttttaaa 142380 atattgttag gtgttgaggt ttgggttttg tgttagattt ttgggtgtag attttgtggg 142440 gatatttatt gggtagtggg atttttggta agttatatta tttttttgag tttttgttga 142500 ttaagttgtt tattgagaat aatatttaga ttgaaaggat ttataataat atgtgaaaag 142560 tgtttggttt aaaataggag tttggtaatt ggtagttttt attatttata atatatagtt 142620 taatgttttt gttttatagg aatgaaaata ggatttagat aggtaaaatg atttgttgag 142680 ggttgtatag tgttaatgat agagttagga ttagggtttg gggttttgat tttttttgta 142740 gtattttggt tttgtgagaa gtggttttgg gtgaatataa ggagtgagga gttggtgaga 142800 aattttgaaa atgaagttgg gtgtggtggt ggatgtttgt ggttttagtt atttaggagg 142860 ttgaggtagg aggattgttt gagtttggga gttggaggtt gtagtgtgtt atgattgtat 142920 tattgtattt tagtttaggt gatttagtaa gattttattt tagaaaagga aaggaaagga 142980 gaggggaggg gaagggaggg aatttttgat agtgatttta gagataatta ggatgatttg 143040 aaattatttt gaaatgtatt aaaaaataaa aataaaatgg atttatggtt aggtgaagga 143100 gggatagatg gatggtgagg tgataaagta ggtgtagttt ggtgttagtg gtagaattta 143160 ggtgatggtt gaatgtgttt tttgtaaaat gtttttaatt tgattatgtg ttttgaatat 143220 ttttataata gaatggaggg aagagaaagg taagagggag ttattgtagt tgttgtagta 143280 ggagtagatt ttaaaatatt atgtattaga tttttagttt tgtttttgtg gatgtgtttt 143340 tgtttttttt tttgggattt aaggatattt aatgagtgta tgtgttttta agtttttttg 143400 tttttttatt tgtttttata tttggaagat tttataggtg gtgtgggtta gttttttatt 143460 ttgttttttg tgtttttagt gtatgataga tattgagtga gtgttagttt ttttttttga 143520 tattttgttt gtttgtttag agaggttttt ttatagttta gttattaggt tgatgttttt 143580 ggatgtttgg ttgatagttt ttttagttgt gttttagtga tttggtaggt gttttgagtt 143640 ataaataagg ttattagtgg atgtttttaa agtttttttt attatggtgt tttttttttt 143700 tttattaata gtttgttatg atagttagtt tgtatgagtt tttttttagg gttgtgtttt 143760 ttgaggttgt ttagtgtttg gtttgttaga gtttattaga tagggtgttt atttttttta 143820 ggtttgagtt tttatttaga gaattattta tagaaggata atggagaaag gtagttgggg 143880 tattaaatgg agtgtgtttg tatgtggggg gggaggggag ggggagggaa agtaggaaga 143940 gaagatataa gaggagaaat aagaataaga ggaaatatag aaggaggagg agtagttttt 144000 tttatggggg tggattttgt gtttagtttt ttattaagga tattatattt attattttgt 144060 ttggttttta tgaatatttt taaggttgtt tttttttggt ttttattttt ttattaggaa 144120 gtggaggtat agagtgagaa agagttgttt aaggttttta ggtagtttat ggagttattg 144180 ggagttatat ttaatttgtt taattttatg tttttgtttt tagttattat aataaattat 144240 taaggtttta tagttatagg agtttagttt ggagttttta ttgggttttt taaggtaggg 144300 agatggggtt ggaggttatg ttaggtgtat ggtgtttaga gttgtttagg aagttttgtg 144360 gtgtgggttg ggtattaggt agtgtttgta ggatggagaa atgaatgagg ttgagatata 144420 gtgttgtttt ttttaaatgt gatttttttt gagtttttgt gattggttat ttgagagggt 144480 agttttggtt ttttggtgtt tatgtttggg tttagagatg ttttttttag ttaggttttt 144540 ttttgaggat ggaaatttag aattttatta taggaggaag agttgggagt attttatttt 144600 tttttttttt ttgagatgga gttttgtttt gttgtttagg ttggagtgta gtgatgtgat 144660 tttggtttat tgtaagtttt gttttttggg tttatgttat ttttttgttt tagttttttg 144720 agtagttggg attataggta tttgttatta tgtttggtta attttttgta tttttagtag 144780 agatggggtt ttattgtgtt agttaggatg gttttgattt tttgattttg tgatttgttt 144840 attttggttt tttaaagtgt tgggattata ggtgtgagtt attgtgtttg gttagggagt 144900 atttttaaga tttttgtgga gggttgttta ggtttaagtt ttttattatg gaaggttttt 144960 tagatgtggt agttatggtg tatgggttga gggtttttat ttattaagaa gtaggagtat 145020 ttgatgtata tttagtttat gatttttatt tatttggggg ttgtgtttgt agttatgtga 145080 tataagggaa tagttatagt agtgggttat aaagagagtg tgggttaatg tgtaggggta 145140 gaattttgat agttttttat gggttggtag tagggagggg tatatttgta taaattttat 145200 atgtatagtt ttttatatat atgtggttga taattattta tatatttaag atgggatttg 145260 gtgtatagtt tattagtaat aggtgttggt aatttttagt tgtttttttg ttgtggtgta 145320 gatattattt aaggtgggat ggagagagtt attgttttta aggttatata ttttaaaggg 145380 agatgttggg ttatggaatg aaaataggag gattagttag agttattggt tttgagttat 145440 ataatgggat atataggttt atttatttta tatttttatt gagtaattat aatgagttaa 145500 gttgtataga ttatttaaat aattggtatg tagaaaagta ttttaatttt tttttggttt 145560 tgatgtgatg ggaagaattt ggatttttgg agttatagag ttggatggaa attttggttt 145620 agttaattat tggttggggg agtttgggta agtgatttaa ggtttttgag tttgtttttt 145680 tgtaaaagag tagtgtttgg gtttgttatg ttaggttagg gtaagatgat tgaagagtaa 145740 gtgtttagta ttggttaggg gttaatgttt ttaaggatgt aaagtgtaat aagtaggtgt 145800 tatgattgta ttgtttttta ttgtttgtgg taaatatata agtaaagatg gttttgtgtt 145860 tgtgttgggg gaggtaggga attggtttta ggaggatgtt ggttttttta gttgtttttt 145920 ttaaagtttt ttgggaggag aaatgattta ttttagttgt tgggagtttt aatttataag 145980 taggtttgtt tatttggtag tggttgtatg taggtaggag gggttttggt agtttttaag 146040 agtgaggggt tgtttagttt ttttttagtt ggaaaggagg ttttaggttg ggtaggagta 146100 tttggggaaa tttagttttt ggagttaggt tatattaggg agatgaggtt gttagaagtt 146160 tttttggtgt ttatagtaaa atataattaa agtgggattt agattttaat tagtttaagg 146220 tttgatttat attagaggga aattagtgtt tgttgtatga gtgagtgttt atgtgtgtgt 146280 aaggtagaga tagattttgg gtaagttttt ttattttttt atgtttgttt ttttatttat 146340 aaaatggggt aatattattt attttatagg gttgttatga aataaatatg tattaatatt 146400 tgtaaagtgt tgagaatagt atttggtata aaataagagt gatagatttg ttaaataagt 146460 aaaaaataag atataagttt aaagtagagt ttggtatatt gtgagtatta agagttgtgt 146520 tttttgattt tttttttttg tggagatttt tttattagaa gtgggaggga ttgttgaggt 146580 tggagttttg ttttagggat ttttgtgggg agttttttag tttagaggga tttgttttat 146640 ggattatatt tgttttgggt ttttgtgttt ttgtgtatgt gtgtatatat gtgtgtatat 146700 atatgtaatg tgtgtgtgtg tatttttatg gatttgtgat aatttgtata tatatgttta 146760 gaatttattt gatatagtgt tttattaaga tgttggagtt ttgatgaatg gattgtgggg 146820 ttgagatatt gtttttatag gaagttgttt tagtagtaag ttttttggtt tttatagata 146880 attaaaaaga atggagtttg tttttatttt ttgttttaaa aatgatgtat agtgtgtggg 146940 gtttgatgtt ggaggttttt ttagtagata tatttttaat aatattatat tttgaaattt 147000 aagttgttgt aaaataagat aagtaaagat ggtattggta gggatttttg aggttttttt 147060 tatgtatttt tgaataattt ttatatggtt tttgtttgaa tgtttttagg tatggggaat 147120 ttattatttt gtgaaatagt ttgttttatt gtttttaagt gaatattgtg agaaaaatat 147180 ttttttttgt aaagagttaa gttttatttg ttagtatttt ttaggtattt ggtattagtt 147240 ttatattttg ggggaattta aaataaatgt ttttttttta ttagataatt tattaattat 147300 ttggagatag tggttgtagt tttttgtttt atgtagttat tttatttagt ttttttttgg 147360 aatttttgat gtgaatataa gtttttttgt tatgtaggtt ttttttttgg gttttttatt 147420 tatttgtgta tattttggag aggttgtttg ttttgtgggt gagatttatt gtgggttgaa 147480 ttgtgttttt ttaaaagata tatgtaagtt ttgatttttt agtatttatg aatgtgattt 147540 tatatggata tagggttttt gaagatgtaa ttgggttatt tgagggtata ttgaattaga 147600 gtgggtttta aatttaatga taggtgtttt tataagatag aggtaggttg ggtatagtag 147660 tttatgtttt taattttagt gttttgggag gtaaagtttt attgtttgag tgtaggagtt 147720 tgagattagt ttgggttttt gtttttataa aaaaattaaa aaattagtta ggtatggtgg 147780 tgtgtgtttg tgttttagtt atttggaagg ttgaggtggg aggattgttt gagtttggga 147840 ggttgaggtt gtagtgagtt atgattatgt tattgtattt tagtttggag gatagaatga 147900 gaatttgttt ttaaaaataa attaaaaaga taatagagag ggtagtttgg atagagatat 147960 aagaagagat atagggtgaa ggttaggtgg ggggtaggtt gagttgtaag ttgaggaata 148020 ttaggggttg ttggttgttg tagagtttgg agaaaggtat gggatagttt tttttggaat 148080 ttttaggagg aatgaatttt tagatatttt ggtttgggat ttttggtttt agaaatttta 148140 gggaagatat tttggatgtt tttgtttttg tttttgtttt tgtttttgag atggagtttt 148200 gttttgttat ttaggttgga gtgtaatggt gtgattttgg tttattgtaa tttttatttt 148260 taaggtttat gttatttttt tgttttagtt ttttgagtag ttgggattat aggtatttat 148320 tattatgttt ggttaatttt tttttttttt ttgtattttt agtagagatg gggttttatt 148380 atgttagtta ggatggtttt gattttttga ttttgtgatt taattgtttt ggttttttaa 148440 agtgttggga ttataggtat gagttattgt atgtggttga ttttggatgt tttgagttat 148500 tttatttgtg gttttttgtt atgatagttg taggatagta atatagggtt ttagtagggt 148560 ggtttggtaa gggttttttt tttatggtag tttttatttt gttttatttg tagggttatt 148620 tagatgttta ttttggtttt ggttagtaag tgttagtgta tttttttatg tttagtagta 148680 agggtagtat tgttgttgat taagtatttg ttatgttggg gtttttgtgt ggttttgggg 148740 tttttttttt ttgtttatat ttggtagttt agtttttttt tttgtatttt atttgatgtt 148800 ggggttttgg gtaagtttgg gggatttgtg ttttatttta tagatttttt agttgatttt 148860 attagttttt gtatagggtt tgtttgaagg gttgttgggt tgggtgttaa ttagagtttt 148920 tagtagtagt ttttttggtt ttttgatttt ggtttatgtt ttaggggtag ggtttttaag 148980 ggttttgggg ttgtttttga ggttagtttt tttgttgatt gtagtttata tagaggaggg 149040 tttaattttg agtgtggttg tttgtgattt tgagagatgt ttagagttgt agatgtgttt 149100 tttaagtttt ttagagtttg ggataggagt tatttaatgt ttttagtgtt ataggtaaaa 149160 tttgtttttt ttaatataaa ttgtttttag ttttatttaa tgtttttttt aatgagtagt 149220 aataaaaata tggttttttg ttaaaggtgg ggtttatagt tttttagaat ttggtttttt 149280 gttaggttta ggtataattt ataggagtgt ttgtttttga tttgtgtgtg tgtgtgtgtg 149340 tgtgtgtgtg tgtgtgtgtg tgtgttgtgt gtatgtgtat atgtgtttgt gtaagttttt 149400 ttatgtgtag ttttgggaag ggtggagagg tttatggaaa ttttttttgg tatttagtaa 149460 gttagaaaaa aggaaaatga gatttgtgta tatatgtgta agtgtatata tagtatatag 149520 gtatatatat atatatattt agtatatatt atataggttt atatgtgtat atatgtgtag 149580 gtatatatta tataggttta tatgtgtata tatatggggg tatatagtat ataggtatat 149640 ataggtatat atattttttt gtaggaaagt ttttttttgt tttttatttt gtagggtttt 149700 taggttttat gaaataagat tgaattttgg aagtttgata aaaggtttgt ttggagtatt 149760 ttggttattt ttattagttt ttttagttgt ggaaggtatg ttttgtggta tttatttatt 149820 ttttgttttt atttttattt ttgtttttgt tttttttttt ttgttttttt agtttatatg 149880 ttgtttgttt taattttaat ttttgtattt ggatgggaat tatttttttt gtagaagggt 149940 gtaatgtatg tggggatata tatatatata tatatatata tattgtattg gaggagagaa 150000 gagaggtaga gtttttttta gatttagagt tttagtgagt gatgggattt tttttagaga 150060 atatgtgtag aagtttgtgt tattggaaga agatattatt ttgatttata tttttttttt 150120 ttttttttgt tttttttata gagaaggaaa ggttttagta aatagtggtt atgtgggttt 150180 tttgtatgtt attggtagtt ttttagttag gattattttt tttttatttt tggaagtata 150240 agaatagaga gaagggtgag tttttgtttt tgggggtttt tttttgtatt tttttggagt 150300 taattttagg gttgtgggtt gtataggaag gagggtttaa taggtttttt gtttaatttt 150360 gtttttttag tgaggagttg atttattttg tttgtaaaag atgttggttg ggatttgatg 150420 ttgggtaatt tgaggagaag agaaggggga taggggttga ggttaggttt ttggttttga 150480 aatagttata atttttgggg tagagtttaa gggtgttagg ttggagattt tatatttggt 150540 tagttggtag ttattatttt ggtttagtta gtggtttagg gtattatagt tatttagatt 150600 aggaatttta tttttttgga ttgtattaat gaggaaggtt gagtttgtag gttttatata 150660 tttatggtaa ttttaaggta gagaggttat tgttaattga gggttatggg taggagtttt 150720 gtgagtttat tagtaagttt ggaagattaa ggtttttggt tatagagagt agttgttatt 150780 tggttaattt tgtagaaaat attatagttt tggataaaat atttgaaaga ataaaataat 150840 aatagtttgg agttagtata gaatatttta agtaggtaga agttggagta gagtttatat 150900 ttgatagagg ggaataaaat tagataagtt tttggttttt ggaggttttt ttgtttagag 150960 gtaggtattg agtaattaaa tttggataaa aagttttaaa agtatttagg gaaaaataat 151020 atgtggttta taggggaata gttagatgaa tgttgatttt ttgatagaaa taatggaggt 151080 taaagatatt ggaattttat attttaaagt tttgaaagaa aaaattgata atttagaatt 151140 ttataattag tgaaattatg gtttaagaat gatagtaggt tgggtatagt ggtttatatt 151200 tataatttta gtattttagg aggttaaagt aggtagatta tttgaggtta ggagtttgag 151260 attagtttgg ttattatggt gaaattttat ttttattaaa aatataaaaa ttagttgggt 151320 atgatggtat atgtttgtag ttttagttat ttgggaggtt gaggtaggag aattgtttga 151380 gtttgggagg agaaggttgg tgagttgaga ttgggtagga gttttgaaat tatattattg 151440 tattgtagtt tgtggggaga tagagtgaga ttttgtttta aaaataaaaa taaaaataaa 151500 aaaagaaaga atgatagtaa aataaagatt tgtagataag tgaaaatgaa agggaattag 151560 ttgtttgtaa atttgtatta taaaaattgt gaagtaagtt ttttaagatt atgggaaatg 151620 agattagatg ggaatttagt tttttaggaa ggaatgaaga gtataggata tagtaaatat 151680 atgggtaaat agaaaagatt ttgttttatt tttaattttt ttaaaatgta tggggttgtt 151740 taaagtaaaa atttttttat tgtattgttt agtttataat gtgtatggat gtagtaaata 151800 tttaataatt attatatata ggatggaaag tggtaaatga atttatagga ttgtttagtt 151860 tttatatttt ttttttatga agaaaaataa tgttaatttt aagtagattg tgaaaagtta 151920 agaatgtgta atagaattta taaagtaatt attaaaatag taatataaag agatataatt 151980 aaaaagttaa aataggttgg gtttagtggt ttatgtttgt aattttagta ttttgggagg 152040 ttagggtggg tggattgttt gaggttagga gtttgaggtt agtttggtta gtatggtgaa 152100 attttgtttt tattaaaaat ataaaaatta gttggttgtg gtggtaggtg tttgtaattt 152160 tagtatatta gggaagttga ggtaggagaa ttatttgaat ttaggaggta gaggttgtag 152220 tgagttaaga ttatgttatt gtattttagt ttgggtaata gagtgagatt ttgttttaaa 152280 aaaaaaaaaa aaaaaaaaat ataaattaaa atagaatttt aaaaaatatt taattaatat 152340 aaaagaagtt aagaaagtaa gatgaaagaa ataaatatta aagagtaagg tagtagtttt 152400 aaatttagtt atatttataa ttatgttaaa tagaaatagt ttgaatattt taattaaaag 152460 gtggaggttg ttagaatgaa taaaatagta agatttaatt atatattatt tataaaagat 152520 gttgttttag tataaatata ggttgaaatt ttttgtttgg aaaaagatat attgatgttg 152580 tttgaatgat gatggagtta tgttttgata aatttattat aagtggaaaa taaatattat 152640 tttaaaaatg tatttaatat atttaattta ttgaatattt tagtttagtt tagtttattt 152700 taatatgatt agaatattta ttttagttta tagttgagta aaattaataa atataaagtt 152760 tattttataa taaagtgttg attattttat gtaagttatt gaatattgta ttgaaagtga 152820 gaaatataat ggttttatat atatttaaag tatagttttt attgtatata tattatgttt 152880 gtattatggt aaagttgaaa aattgtaagt taaattatta taagtttttt tataagtttt 152940 tttagttttt ttatgtattt taaatagtat gtttaagaag gttggagagg ttatataaat 153000 attaataaag ttgagtttaa gataaaatta ttatgagata aaggaatata tttattatgg 153060 ttaaatgatt agtttattga gatattatta taattataaa tgtgtatgta tttaattaaa 153120 ggagttttaa aatatatgat ataaaatttg aaagaattaa agggagaaat gggtaatttt 153180 ataattatag gtggagattt tttttttttt tttttgagat ggagttttat ttttgttgtt 153240 taggttggag tataatggtg taattttggt ttattgtaat ttttattttt tgggtttaag 153300 tgattttttt gttttagttt tttgagtagt tgggattata ggagtttgtt attatgttta 153360 gttaattttt gtatttttag tagagataag gttttattat gttgtttagg ttggttttaa 153420 atttttgatt ttaggtgatt tatttgtttt ggttttttga agtgttggga ttataggtgt 153480 gagttattgt gtttggatgt atagttggag attttaatat tattttagtt tatttaggat 153540 gttaaaataa aatgttttag gttgggtaat ttataaatag attgtagtgt ttatagtttt 153600 agaggttggg aagtttaaaa ttagggtgtt tagtgtttgg tgagagttag ttttttgttt 153660 tagagatgtt ttttttttgt tgtgttttta tatggtagaa gggattaatt ttatttatga 153720 tgattttgtt tttatgagtt aatatttttt tgatgtttta atttttaata ttattgtatt 153780 agagattaag ttttaatata tgaattttgg gggatataaa taggtaggtt atagtaaata 153840 ttattttttt aatatttgag aaataagtat tagataattt gaagaatatt ggtaattagt 153900 aattgattta attagtagtt ataaagtttt atatttagga agtttagaat atatatatat 153960 attttttttt taagtgaaaa tagtgtattt attaagatat atattttggg ttataagttt 154020 taaattttaa aagtatgtaa aatatgtttg tttggttaaa gtaagattaa attagaaatt 154080 aatagtttta agatatttag aggagttttg attatttgta aattaaataa tatattttta 154140 aataatttat gagttaaaga ggaaattata agaaaaattt tataatattt taaatgaaat 154200 gataatgaaa atatagtata ttaaaatatg taggttgaag ttagtgttta gagggaaatt 154260 gtaagtgttt atattagaaa agaagtaaaa aaaaaaaaaa aaaaaaaaaa aaaaagattt 154320 aaggatttgt tttaagaatt tggaaaaatg ggttaggtgt agtgtagttt atgtttgtaa 154380 ttttagtatt ttgggaggtt aaggtaggtg gattatttga gattaggagt ttaagattag 154440 tttggttaat atggtgaaat tttgttttta ttaaaaatat aaaaattagt tgggtatggt 154500 gggtattttt agttatttag aaggttgagg taggagaatg gtttgaattt gggaggtgga 154560 ggttgtagtg agtttagatt atgttattgt attttagttt gggtaataga gtaggatgtt 154620 tttttaaaat aaaataaaat aaaataaaat aaaataaaat aataaaaaaa ataaagaatt 154680 tggaaaaata tgttagttat ttatgtattg ttttttaatt ttgtatatat tttgttaggt 154740 tttgttttgt gatattggat tgaggtttta tgagtttttt tttttggtta aatatagtta 154800 tgttaggttt tatttatagg ggataatatt gtggggagtt gttaggtttt gttgaggtag 154860 tagttttttt ttttggtttt agggtttttt ttttttttga aggtatagtt gttagtggtg 154920 tgtgtttagt ggggtttgtt ttgtattgag tttttttagt attttagttt tagtttaatg 154980 ggattttagt aaatttttta gatatttagt ttttgtttat ttatattttt tagtaggttt 155040 tttggttatt tagtaagttg attttgtaga tttatttttt ttatattttt tggtaagaat 155100 ttttttgtta ttagtaggtt gtaggttttt gtggtagtta tatatttttt aataaggttt 155160 gaatgtaaga tgtggtaagg tgtggaggat gttttgagtt tttggttttt tttttattaa 155220 ttttagtggt agtaattgtt tttgtgtgtt tgtatatatg ttttaaagta tttattatag 155280 aaaatttatt attttaatta tttttaggtg tgtagtttgg tggtatgaag tatatttata 155340 ttgttgtgta attattatta ttatttattt tattttttta aattgtaatt ttatttttat 155400 taaatattaa ttttttattt attttttttt tttttagttt ttggtaattt ttattttatt 155460 ttttgttttt ttgaatttga ttattttagg gattttataa aagtgaaatt atatagtatt 155520 tgttttttta tgtttggttt ttgttattta gtatgttttt aaggtttatt tatgttatag 155580 tatgtgttag aatttttttt tttttttttt tttttttttt ttttgaggta gttttgtttt 155640 gttgtttaag ttggagtgta gtggtatggt tttggtttat tgtaattttt atttttttag 155700 tttaagtgat ttttttgttt tagttttttt agtagttggg attataggta tatgttttta 155760 tgtttggtta atttttgtat ttttagtaga gatagggttt tgttatgttg gttaggttag 155820 ttttaaattt ttgattttaa gtgatttgtt tattttggtt ttttaaagtg ttgggattat 155880 aggtgtgagt tattatattt ggtttttttt ttttttttaa ggtagaataa tattttattg 155940 tatagatgga ttatattttg tttgtttatt tatttgttgg tggatatttg ggttgtttgt 156000 attttttggt tatgggaaaa gtgttgttat aaataagaat gtagtatatt tgtttaagtt 156060 tttgttgtta gttttttgga gtatatattt agaagtggaa ttattggatg ttatggttat 156120 tttgagttta attttttgag taattgttat atttttttta tagtagttgt attattttat 156180 atttttatta gtagtgtatg gggttttaat ttttttatat ttttgttaat atttgttgtt 156240 atttatgttt tggttaatag ttattttaaa gggtgtgaaa ttatatttta ttgtggtttt 156300 gatttttatt tttttgatga ttagtgatat tgtgtatttt tttttgtgtt ttttggttat 156360 tggtatgttt tttgtggaaa aatgtttgtt tattgggttg tttttttttg ttttgtggtt 156420 tagttgtagg agttttttat atattttgga tattagtttt ttattggata tatgattttt 156480 aaatattttt ttttattttg tggatttttt ttttatgtta ttggtagtat tttttgatgt 156540 ataaaagttt taagttttgg tgaagtttaa tttattattt attttttttg ttgtattttt 156600 ggtgttatat ttaagaaagt attgttaatt ttaatgttat gaagtttttt ttttatgttt 156660 ttttttaaag tagttgtttt ttatatttgt tttttttata ttttttagag tttttttgta 156720 taaggtaaaa taaattttat ttttttattt ttatttataa tatttagtgt tttagttttg 156780 atattagatg tgtggttttt ttttgttgat ttttaagtaa ttttttaata tttagtagtt 156840 tttaattggg tgttttgtaa tttagtttaa ttttgatatt aattagagtt agtgtagatt 156900 ttataggtta agggttttat tttataagat tgtttttaat tttagagatt agttgtaagt 156960 ggtaagatat taggttattt ataatttttg tttgatttgg ttataaattt gaggttttta 157020 taattttttt tttaggttta ataatttgtt tgagtgattt atagaattta ggaaattagt 157080 ttatttaaaa ttgttgattt attataaatg atattttaaa ggatataaat gaatagttaa 157140 ttggaagaga tgtataagaa aggtatgaag gaagtggtat ggagttttta tgggagggta 157200 tattgttttt ttagtatttg taggtattta ataatttgaa attttataaa ttttattttt 157260 ttgggttttt agggaggttt tattatataa gtatgatatg aaatttttgg ttattgatga 157320 ttaatttaat ttttattttt ttttgttttg taggaggtgg atgggaaagg ttgtaagttt 157380 tagtttttta attataaggt tgggtttttt ggtaattagt ttttattttt aggttgttta 157440 ggagttttta gttattagtt gtttttttag taaataaaaa gatatttatt attttggaga 157500 ttttaagagt tttaggagtt atatgttaaa taaagttggg ggatagagat tagatagata 157560 gatagataga tagatagata gatagataga tagatagata gatagatata ttgatttttg 157620 agatagagtt tttttttgtt atttaggttg gagtgtagta gtgtaatttt ggtttattat 157680 aatgtttgtt tttttgggtt taaattattt ttttatttta attttttaag tagttggaat 157740 tgtaggtata tattgttatg ttaggataat tttttgtatt tttggtagat atgaggtttt 157800 attatgttgt ttaggttggt tttaaatttt tgagtttaag ggatttgttt gttttagttt 157860 tttaaagtgt tgggattata aatatgagtt attgtattga gtttagttta aatatatttt 157920 ttttatatta taatgttatt tttttgtgat ttttttaata gttaattatt ttttatagtt 157980 aagaatattt tatattataa gttgttattt aaattgttgg tgtggttttt gttttttgat 158040 tgggttttga ttaatgtgtt gaagtaagta taaggaagga agtaatgaag ataatagaga 158100 aatttaagga aatggatatt agaaaagggg agtttaatgt tggtttttta aaaagattta 158160 gattgataat tttttagtta ggttgttgat gagagggaga tggtgaatat aaagttataa 158220 taaaaggaat gaagtgtttt ttttatggat tttattgata ttatagtgat aaggaatata 158280 ggtatatttt attttattgt gttttataga tattgtattt tttataaatt gaaggtttgt 158340 ggtagttttg tattaagtaa gtttgttggt attatttttt taataatatg ttaatattgt 158400 gtttttgtgt aggagtttga tgatttttga aatagtttaa atttttttat tattattata 158460 tttgttatgg tgatttgtga tttttttttt tttttttttt tttttgtttt tttttttttg 158520 agatagagtt ttgttttgtt tggagtgtag tggtgtgatt ttggtttatt gtaagttttg 158580 ttttttgggt ttatgttatt tttttgtttt agttttttga gtagttggga ttataggtat 158640 ttattattat gtttggttat tttttttgta tttttagtag agatggggtt ttattgtgtt 158700 agttaggatg gttttaattt tttgatttta tgatttgttt gttttggttt tttaaagtgt 158760 tgggattata ggtgtgagtt attgtgtttg gttttttttt tttttttttg agatggagtt 158820 ttgttttgtt gtttaggttg gagtgtagtg gagtgtagtg gtgtgatttt ggtttattgt 158880 aatttttatt ttttaggttt aagtgatttt tttgttttag tttttttagt agttgggatt 158940 ataggtattt gttattatgt ttggttaatt ttggtatttt tagtagagat gaggttttat 159000 tatgttggtt aggttggttt taaatttttg attttaggtg atttatttgt tttggttttt 159060 taaagtgttg ggattatagg tatgggttat tgtgtttagt gattagtgat ttttaatgtt 159120 attattgtag ttgtttttgg ggtatgatga gttatattta gataagatag tgaatttatt 159180 taataaatgt tgtatgtttt gattgtttta ttgattggtt gttttttgtt tttttttttt 159240 ttgtttaggt atttttattt tttgagattt aataatattg aaattaggtt aattaataat 159300 tttataatgg tttttaagtg tttaagtgaa aggaagagtt atttgttttt tattttaaat 159360 taaaagttag aaatgattaa gttgagtgag gaaggtgtgt tgaaagttaa gataggtaaa 159420 agtgagattt tttatgttaa atagttagtt aagttgtgaa tgttaagaaa aagttattga 159480 aagaaattaa aagtgtgatt ttagtgtata tatgaagaag aagaaagtaa aatagtttta 159540 atgttgatat gaagaaagtt tgagtggttt ggatagaaga ttaaattagt tataatattt 159600 ttttaaataa aagtttaatt tagggtaaag ttttaatttt ttttaatggt atgaaggtta 159660 agagaagtga ggaagttgga gaaggaaagt ttgaggttag tagaggttag gttatgaagt 159720 ttaaggaaag aagttatttt tataatgtaa aagtgtaagg tgaagtagta ggtgttgatg 159780 gagaagtggt agtaagttat ttagaagatt tagtttagag tattgatgaa ggtggttata 159840 ttaagtaata gaattttagt atagatgttt tattttttat tggaagaaga tgttatttag 159900 gatttttata gttagagggg agaagttaat gtttgttttt aaagttttaa aggataggtt 159960 gatttttatg agaggttaat gtagttgttg attgtaagtt aaagttaata tttattgatt 160020 gttttaaaaa ttttagggtt tttaagaatt ttgttaaatt tattttgttt atgttttaga 160080 aatggaataa taggttttat ttgatagtat atttgtttat agtatggttt attgaatatt 160140 aaaaatttat tgaggtttgg tgtggtaatt tatgtttgta attttagtat ttttgaaggt 160200 tggggtgggg ggattatttg aggttaggag tttgagatta gtttggttaa tatggtgaaa 160260 ttgtattttt attaaaaata taaaaattat ttaggtatgg tgttatatgt ttgtaatttt 160320 agttatttgg gaggttgagg taggagaatt gtttgagttt aggaggtgga ggttgtagtg 160380 agttgagatt gtgttattgt attttagttt gggtaataga gggagatttt gttttaattt 160440 gaaaaaaaat aaaaaaataa aaaagggtta agtatggtgg tttatagttg taattttagt 160500 attttgggag gttaaggtag gtaaattatt tgagtttagg agtttaagat tagtttggtt 160560 aatatggtgg tgaaatttta tttttattaa aaatataaaa attagttagg tatggtagtg 160620 tatatttgta gttttagtta tttaggaggt tgaggtagga gaattatttg aatttgggag 160680 gtggaggttg tggtgagttg agatagtgtt gttgtatttt agtttaggta ataaagtgag 160740 attttgtttt aattaaaaaa taataataaa aaaaaaataa atagggtttg gtgtagtggt 160800 ttatgtttgt agttttaatg ttttgagagg ttgaggtagg tggattattt gaggttagga 160860 gtttgagatt agtttggtta atatggtgaa attttgtttt tataaaaaat ataaaaatta 160920 gttaagtatg gtggtgtgtg tttgtaattt taattattta ggaggttgag gtataagaat 160980 tatttgaatt tgggaggtag aggttataat gagttgagat tatgttattg tattttattt 161040 tgggtgatat agtgagattt tattaaaaaa aaaaaaaaat tattgagatt tattgtttag 161100 gaaaaaagaa tttttttaaa atattattgt ttattgataa tgtattttgt gatttaagag 161160 ttttgatgga gatgtatgta aagatgaatg ttgtttttat gtttgttaat gtaatattta 161220 ttttgtagtt tatggagaag ggataaattt gatttttaag ttttattatt taagaaatat 161280 attttataaa gtagtatttg ttatagttag tgattttttt aatggatttg ggtaaagtaa 161340 attgaaaatt ttttggaaag gattttttat tttagatgtt attaagaata tttgtgattt 161400 ataagaagag gttgaaatat taatattaat aggagtttgg aagaagttga ttttaatttt 161460 tatggatgag tggtttaaga ttttagtaga ggaagttatt gtagatgtgg tggaaatagt 161520 agagaattag aattagaagt ggagtttgga gatgggattg gattgttgta attttatgat 161580 taaatttgaa tagatgagga gttgtttttt atggatgagt agataaagtg gtttttggag 161640 atgggattta ttttaggtga agatgttgtg aatattgttg aaatgataat aaaagattta 161700 gaatattata ttaatttatt tgattaattt gtggttaggg ttgaaagaat tgattttaat 161760 tttgaaggaa gttttattgt gggtaagatg ttattaaata taatgtgtgt tatagaaaaa 161820 ttttttatga aagaaagagt taatttatgt taaaaatttt agttaagaaa ttgttggtta 161880 ggtgtagtgg tttatgtttg taattttagt attttgggag gttaaggtag gtggattatt 161940 tgaggttagg agtttgagat tagtttggtt aataaggtga aattttgttt ttattaaaaa 162000 tataaaaatt agttaggtgt ggtggtaggt atttgtagtt ttagttattt gggaggttga 162060 ggtaggagaa ttgtttgaat ttgggaggta gaggttgtag tgagttgaaa ttgtgttatt 162120 gtattttagt ttgggtaata gagtaagatt ttgttttaaa aaaaaagaaa aagaaaaaag 162180 aaataaagaa attgttgtta tagttatttt taatttttag taattattat ttggttagta 162240 gttattaata ttgaggtaga ttttttatta agaaaaagat tatggtttgt tgaaggttta 162300 gatgattatt agtatttttt agtaaaaaga tataatgatt ttatatattt taatagatta 162360 tagtatagtg taaatataat tttttttttt tttttttgag atggagtttt gttttgttat 162420 ttagtttgga gtatagtggt gtgattttag tttattgtaa tttttatttt ttaggtttga 162480 gtaatttttt tattttagtt ttttaagtag ttgggattat aggtatgtgt tattatattt 162540 agttaatttt tgtattttta atagagatga ggttttatta tgttggttag gttgttttta 162600 aatttttaat tttaaatgat ttgtttattt tggtttttta aagggttagg attataggta 162660 tgagttatta tgtttggttt aaatataatt tttatatgta ttgggaaatt aaaaagtttg 162720 tgtgatgtgt tttattgtaa tatttgtttt attgttgagg tttggaagta aattttaggt 162780 atgtttgtat tatgaataat tttaaatgag taaatttaat aatttatttg aaagggataa 162840 atttttttaa agtataattt attaaaagta agataagggg aagtaaaaaa atttgaataa 162900 ttttttttat atattaaatt gaatttgtga ttaaaaataa ataattattt tttttagtag 162960 aaaattttag gtttagatgg tttttttggt ggattttatt aaatatttaa ggaagaaata 163020 atattaattt tatgaaaata tagaaaataa agagaaggga atatttttaa attaatttta 163080 tgaagttaaa atgaggttga taaagatatt attgaaataa attaataaat aaagaaaata 163140 ttatattaat attttttatg aattaatatg taaaaatttt taaaaattgg gtaaattaaa 163200 tttagtaata tataaaaagg atgatatttt ataagtaagt tggatttttt ttagaaatgt 163260 aaggttggtt taatattaaa aaattaggtt tgtatagtgg tttatatttg taattttagt 163320 attttgggag gtagaggtgg gagtattgtt taagtttaag aattgtagat tagtttgagt 163380 aatataatga gattttattt gtataaaaaa ttttaaaaat taaaaattag tttggtatgg 163440 tggtatgtgt ttatagtttt tgttatttag gaggttgagg tgggaggatt gtttaagttt 163500 aggagtttag gttgtagtga gttatgatgg tattattgtg ttatagtttg ggtaagagtg 163560 agattttgtt tttttaaaaa aaaaaaaaaa aaaaatgggg ggtaaaaatt aattattgta 163620 atttatttta ttaaatgaat aaaagataaa ataatgatta tttttataga tgtagaaaaa 163680 gtatttatta aaattatatt tatttatgtt aaaaaatttt agtaaattaa gaatagaagg 163740 gaattttttt aatttgataa aggttatata tgataaattt aaagttaata ttataagttt 163800 ggtataggta aggatgttta ttaattatta ttatttaata ttgaattggt agttttaatt 163860 agtgtaataa agtaagaaaa aaaaataagg tattaagatt agaaagaagt aaaattatgt 163920 atttaaattt taaaagattt ataaaattat tattagagta ataaatgatt ttggaaaaga 163980 ttataggata taagatttat atataaaaat ttattgtatt tttatatatt agtagtaaat 164040 aattaaaaat gaaatttaaa atttatttta gtttaaaata gtgttaaaag taaaattttt 164100 aggaataaat ttaataaatg gtatgtaaga tttttttttt gaaaattata aaataatgta 164160 attttgtaga gatttttttt tagtagagaa ataaaagaaa tataaaagga tttttaaaat 164220 ggagatatat tatttatata aaagatttaa tattgttaaa atgttaattt ttttttaatt 164280 gatttataga tttaatataa ttttaattaa aatttatatt gtatttttgt agatattaat 164340 aagttatttt ttaaatttat aaggaaattt aaaggattta gaatatttaa agtaatattt 164400 tagatatttg agagatttta tattaagatt tattgtaaag ttatattaat taagatgtgg 164460 tattagtaaa ggaatggata aaatattaag aaaatataat agtgttttaa tatagggttt 164520 atatgtatat agtatatata ttaatatagg attatatata tagttaatat aggatttata 164580 tgtatatagt atatatatta atataggatt atatatatag ttaatatagg atttatatgt 164640 atatatgtat atatattaat ataggattat atatatagtt aatatggggt ttatatgtat 164700 atatgtatat atattaatat aggattatat atatatatat agttaatata gggtttatat 164760 gtatatatgt atatatatta atataggatt atatatatag ttaatatagg gtttatatgt 164820 atatatgtat atatattaat ataggattat atatatagtt aatatagggt ttatatgtat 164880 atatgtatat atattaatat aggattatat atatagttaa tatagggttt atatgtatat 164940 atgtatatat attaatatag gattatatat atagttaata tggggtttat atgtatatat 165000 gtatatatat taatatagga ttatatatat agttaatata gggtttatat gtatatatgt 165060 atatatatta atataggatt atatatatag ttaatatagg gtttatatgt atatatgtat 165120 atatattaat ataagattat atatatagtt aatatggggt ttatatgtat atatgtatat 165180 atattaatat aggattatat atatagttaa tatggggttt atatgtatat atgtatatat 165240 attaatatag gattatatat atagttaata tggggtttat atgtatatat gtatatatat 165300 taatatagga ttatatatat agttaatatg gggtttatat gtatatatgt atatatatta 165360 atataggatt atatatatag ttaatatagg gtttatatgt ataaatgtat atatattaat 165420 ataggattat atatatagtt aatatagggt ttatatgtat atatgtatat atattaatat 165480 aggattatat atatagttaa tatagggttg atatgtatat attaatatag gattatatat 165540 atagttaata tagggttaat atgtatatat gtatatatat taatatagga ttatatatat 165600 agttaatata gggtttatat gtatatatgt atatatatta atatagggtt atatatatag 165660 ttaatgattt ttagtaaagg tgttaggtaa tttaatagag taaggtatgt ttttttaata 165720 aatggtgtta gaattggata tgagtataga aaaataagaa ttaattttga ttttaaatta 165780 aatataaaaa ttgatttaaa atggattata taatattttg atggttataa taggttaaaa 165840 aatgtaaaaa tttaaaaaat taaaaaataa aaggaattat agaatatata attataaaat 165900 ttttagaaaa taagagaatt ttttttgatt ttagtgtagg taaagatttt ttttataggt 165960 tataaaaatt ataaattgaa attggaaaaa gttgataaat tggattttat gaaaataaaa 166020 tatttttgtt tattaaataa tattattaag aaaattaaaa ggaaaggagt aatgtggaaa 166080 aaaaaattta tgatatatat atttgataaa ggatttatat ttagaatata taaaaaatat 166140 atgaaataat attttttttt tttttttttt ttgagataga gttttgtttt gttatttagg 166200 ttggagtgta gtggtgtaat tttggtttat tgtaagtttt gttttttagg tttatattat 166260 ttttttgttt tggttttttg attatttggg attataggtg tttgttatta tgtttggtta 166320 attttttgta tttttagtag agatggggtt ttattgtgtt agttaggatg gttttgattt 166380 tttgattttg tgatttgttt gttttggttt tttaaagtgt tgggattata ggtgtgagtt 166440 attgtgtttg gttaattttt tttttaaatg agatttatgg ggaaatagtt aaatgaagaa 166500 ataataaagt agtaataaaa taaaatttaa gttttatttt attgtgtagt tgtaggataa 166560 agagtagaag tttgtagttg gggaataagg tgtttatttt tttaagtatt ataaaatgaa 166620 ggttttagaa attatttgat tttgaaataa tataatttta aaaagaagta agatgtggat 166680 agataatttt ataaaggaaa atatgtaaat gattaataag gattttggaa aattgtgtga 166740 ttttataagt tattaagaaa atataaaata aaagttttaa aaaaaaatga agtttggaat 166800 aattgaataa atatataaaa tgataataaa atgaattttg attttttatt ttatattata 166860 tgtaaaagtt aatttataaa agttatataa ttttaagttt tttaaaggaa aatataaata 166920 tttttgtaat ttggtagggt aggtaaaggt tttttataaa gaatatagag agagaattat 166980 aaagaaagga gtttgttaaa ttagatttta taaaaattaa agtgatatat ttttgtttat 167040 tggaaaatat tattaagaaa atgaataggt tgggtatggt ggtttatgtt tgtaaaattg 167100 gtttttgggg aggtagaggt aggaggatag tttgagttta ggagttttag atttgtttgg 167160 gtaatatagt gagattttgt ttttgaaaaa ggaaagaaaa tgaataggta agttatagat 167220 tggaataaaa tatttgtaaa atatgtattt gataaaagat tagtatttag aagaaaaagt 167280 taagtaattt aattttaaaa tgagtaatag atttgaaaag atattttata aaggaaaaat 167340 atatgaagag ttaattatga aaatgtgttt aattgtatta gttattaggt taaagtaaat 167400 taaagttata atgagatgat attattatat gtttattaga atgattaaga ttttatagag 167460 tgatagtatt aaatgttggt taggatgtgg agtaattaga atttgtattt attgttggtg 167520 ggagtgtgaa atggaagggt tattttggga aaagatttgg tagtttttta taaaattaaa 167580 tgtatattta ttttatattt attttaggtg tttttataga ataaatgaat gtttatatgt 167640 atagaaaaat ttgtataaga agaattagtg taataggttt atttataaga gtttttagat 167700 ggaaatagtt aggggttttt taataagaga atgattaaaa atttatagaa tgtttatata 167760 gtggatgtta tttagtaata aaatagaata aattgttggt atttgtagta atatgggtag 167820 ttttaagaaa tatttaaatt ggtaaaatta ttttgtggtg gaaaaaaagt ataattgtgg 167880 ttgttttggg gaaggtgggg attgtgatgt atttggaggg gtatgaggaa tttattgggg 167940 tgatagtgat gttttatgtt ttggttaggt tgggatatat gtggatattt ttgttaaaat 168000 ttaaagaatg gaatgtttta tatttgtgta ttttagggta tatatatttt attttaaaga 168060 aaaataaaaa taattataga taaatgttgg attttagtta atgaaatgta aattgaggtg 168120 ttgataggat gttgtgtgtt gatttttgta gtttatttta agtgtattaa aattagtgtg 168180 gatgttggtg gttagaggga tttgtggtga agtaaatagt aaaatggttg ttgtggaatt 168240 taggtggtag gtgtatgggt gtttatttta gaatttttta tggttttttt tttgtggttt 168300 tgttttgttt tgtttttgag atagggtttt gttttgttgt ttaggttgga gtgtattggt 168360 ataattttag tttattgtag ttttaatttt ttaggtttaa gtaatttttt tattttaatt 168420 ttttgagtag ttgggatttt aagtttgtat tattatgttt gattaatttt ttgtattttt 168480 tatagagatg ggattttatt atattgtttg ggttggtttt gaatttttgg gtttaagtga 168540 tttttttatt ttaatttttt aaagtgttgg gattatagtt atgagttatt atatttagtt 168600 tttttttatt ttttttatgt ttgaaaagtt ttatggtaaa aagttggaaa aatgtaaaaa 168660 agattgaaat ttattaatta aaaataggaa aaataaaata aaagagatgg taggagatta 168720 tttttttttt ttttaattta gtttttaatt tttttttttt ttgtttagtt aggataggaa 168780 ttttaagggt ttgggttttt tgtgtttgtg tggggaagga ggtatttttg tgtttgtgtg 168840 ggggttggtt atttgttttt tggtgtattt tttgtatttt attttttttt gtttgtagtg 168900 agtagttata gttggtggaa attatattta ggtagttttt gtttataaat ttagtgaaaa 168960 tgtaaatttt gtaggagttg gatttttgag agtttgtggt gttatttgtt ggaggaaagg 169020 ttttttgtat ttgagttttt tttttttttt ttgttgttat ttgttttttt gtttaggttg 169080 ggtgggtttt ttttttgtaa ttttggggta ttggtgtatg ggaaatgttt agtgttttat 169140 aatttttttt tatttatatt ttaatattta gtttttagtg gatattgttt ttgtttgata 169200 aatatattat ataggtatag tttaagatta tttattttag gaggagtata agttttagtg 169260 tttattattt tagttttttt tttttttttt ttgatgtagt gatataggtt taggatattg 169320 aagatttttg attttataaa tatgttgaag ttaattattt tgaagttgta gtttttatta 169380 ttattattat tttttatttt ttgtaaagat aaagttttgt tatgttgttt agtttggttt 169440 ggaatttttg gatttaattg atttttttgt tttggttttt taaagttttg ggattgtagg 169500 tgtgagttat tgtatttagt ttgaagttgt agttttttaa ttattgttaa tagtaatatt 169560 tatttttttg tgagtagtag ggtttgttgg tatggttgat agttttgtat tattgtattg 169620 aatttgttgt ttgggatttt aggtgagttt tgatttttag ttggagggat aagttgtgtg 169680 gggttgggta gggtgaattg tgggagatta agtttagatt gagggttata agttatatga 169740 gtattggggt taggtaggga tagtgaagga gatagtgtaa ttttgaggaa agataatgtt 169800 atagaatgga gaggtttagg tttggggttt ttttttgttg ttggataggt atgtttgtgt 169860 ttttttttta gtttttgtga tggttaagtt atgtgttttt tgagaggtaa gtgaggtttt 169920 tgatagtagg ttttaggttt taattaaatt gtttgttttg tagggtgagt tgtataggtg 169980 tttttatttt tgattttttt gaatttttgt tgtttttaag ttttatttat tttttttagg 170040 tgaatagaaa tattgtttag gggagaatgg aggaagaatt taggaaaggt tgtttgagag 170100 tttggttgag tttatgttat tgttaagagt agtgttaaaa tttaggagtt ggtgagatta 170160 tggtttaggg tttatattaa tatgaggggg tgttagtttt atgattaatg agtttttgtt 170220 ttattatttt ttgttattta tattttgagg gttatagtta gtatgtgaat tggagttggt 170280 ttttggtatt ttttttttta tattagtttt ataatgtgag gtgggggttt gtttttagag 170340 gtatttggag tagtaggtgt tttaagaggg ggaagttttt ttgaagtttt tttttattta 170400 tggtatagga tgtagagggg atagagtatt aggaatattt agtgattata ggggtttgtt 170460 ttgaaggaga ggaggtagga ggtagggaga gtggttggga ggttagtttt ggagtgttta 170520 ttttttattt tgagggagag gaaggaagta gaaggtgagt atagggagtt ttagttgggg 170580 atggagtggg ggttgtagtt tgattgtgtt gtttggagtg ggggtatgga ttgtagtttt 170640 tatttatttg tttggttagt ttgaagttat tttaagtttg gagattttat ttgttttgtt 170700 tatttttttt agggatggtg tttaaatttt gaagttttgg ttggtgttgt aaatatggga 170760 gggaggtttt gttttatttt agttttaaga gttagttaag aatgttttgg atatttgaat 170820 tttgttttga gttagaggtt gggaagaaat ttgaaggatg gtgggatggt ggatagtagt 170880 ttttaggtat taggtattag ggtttttgtt tggggatggg ggtattagta ggtgttaagt 170940 gtattatatt agggtttatt atgtttttgt ttagagattt agtattttat gaaataggaa 171000 ggaatgaggg atgagtgtgt tttttttttt aatattttag tttttgtttt gaggttgtta 171060 ggtatttaat ttttttagga tttaaattat tttggtttta tttatggtta agtgtattaa 171120 attatagtta ggattattgg gtttagatat taaaagtgtt ttttttaaag ttggtagtta 171180 ttagggtagt atagggtagt gtaaggttgg gtagggttgg ttatttgtta gtatttagtg 171240 gtttttgttg gatgttgatg ggggtagtta ggtaggtggg tttatttagt aattaaagag 171300 attttttttt tttaattttt tttttaaaga gattttgatt tttttttttt agttgtaggg 171360 tttgtagtag tttttttttt agtaggtttt tttgtttgtt tttggttatt tttagtagtt 171420 atagggtatt gaggttttat tatagtgaga ataaaattaa gtttttatta gggtttttaa 171480 ggtttggtat gatttggttt tgtttgttgt attggtgtta ttatggtttg tttttgaaaa 171540 tatattttag ttatttttat tttttttagg ttttagtttt gggtttttat atttgttgtt 171600 ttttttgtta ggttgttttt tttttggatt ttggtttggt tgggtttttt tggttattat 171660 agttttagtt tagtgttatt atttagaaag ggtttttatt aatttttttg ttatatatat 171720 agatatgtat ttttagtaat ttgtttttag tttttttata gtttttattt aaaattattt 171780 atggatttgt ttatttgtgg attgtttttt agttttaatt gttaagtaat aagtgattag 171840 tgattgtgtt tttgttgttt tttattatag gttaagtatt taagagaggg gttgtatata 171900 gtaggtttta ataaatattt attagatggg ttaggtatgg tggtttatgt ttgtaatttt 171960 agtattttgg gaggttaagt tgggtggatt atttgaggtt aggagattgg gattagtttg 172020 attaatatgg tgaaatttta tttttattaa aaatataaaa attaattagg tatggtggtg 172080 gatgtttgtt attttagtta tttgggaggt tgaggtagga gaattgtttg aatttgggag 172140 gtggaggttg tagtgaggtg agatggtgtt attgtatttt agtttgggtg atggagtgag 172200 attttgtatt aaataataat aataaaatat ttgttagaag aattaaagta gtttgtttgt 172260 gtttaatagg aatttaagag tataagatga atttaattaa aggatatata tagtaggtat 172320 tttatagttg atatttgttg gtggagggag attaggaaag tggggagagg tagtgtttgg 172380 gtatggggat attttgggta tggggatgtt ttggatatag ggatatattg ggtatgggga 172440 tattttgggt ataggatgtt ttgggaatgg ggatattttg ggtatgggga tattttgggt 172500 atggggatgt tttggatata gggatatttt gggtatgggg aaattttggg tatggggatg 172560 ttttggatat agggatatat taggtatggg gatattttgg gtatggggat gttttggata 172620 tagggatata ttgggtatgg ggaaattttg agtattggga tgttttaggt atggggatgt 172680 tttttgttat ttgaaatttt gtagttttat tatatttgtt tgttttagta aattggttta 172740 aagagtattt ttaagttttt atggtaaagt tttagagtta gtgttttttt gttgattttg 172800 agggtgtgtt gtttatttag tgtttaagtt agagtttttt tatttagaaa aaaaaagagg 172860 agggtggttt tatggatgga ggtatgaggg tgtttatagg tagagggagt ttttgggttg 172920 agatttgtgt tattttttgt tttaatttta aggtgtagtt tggagtttaa attagttttt 172980 aaatgtgggt tgttggttaa gaggaatttt tttatttatg attttttttt atatttagtt 173040 tttattgttt agagtatgtt agttttgttt gttttggttt ttaggatttt tttagggatt 173100 tttaggtttt aagttagggt gggtttgaat taaggtagtt ttagaattta tgttaatgtt 173160 tttgttagtg ggagattttg gggagtattg tgtgggatgt atggggttag gtgggggtat 173220 atagtgagtg gttttagaag ttttggttgt ttggagtggg ggggtgttta gagtaagaga 173280 tgggttagga agttggagtg agtaaggagg ttttagtttt tggtgggagt aggttgggta 173340 aaaataaatt aatttgaggg tagtagttag tgagattatt ataggagggg tggtggggtt 173400 ggaggggttt taggagttta ggagagggag gtattgttag aggtaaggtt ggtagatgag 173460 agttagtgtt ggtaggatta atttgttata gtagttatgg tttatttttt tttttttttt 173520 ttatatatgt ttttggggtt tatggaattt attagtttat tataaaggat attataaagg 173580 atatagggga agagatgtgt agggtaaggt atgggggagg gatgtagagt ttttatgtgt 173640 tttttaggtg ttttattttt taggagtttt tatatgttta tttatttaga agtttttgga 173700 attttatttt tttgagtgtt tatggaggtt ttattatgaa ggtatgattg atttaattat 173760 tggttgttga tgatttgttt aatttttagt tttttttttt tatttggagg ttgtggggtg 173820 gtgttgaatt ttgtgatttt atttggtttt ttttgggaat tattttgaag ttgttagttg 173880 gtttgttaat tatgagtatt taaaaagata ttattttgga gattttaagg attttaggag 173940 ttgtgtgtta ggaaatggag atgaaaatta agtgtatatt ttataatatg atagttagtt 174000 ttttttaatt ttagttttat tttttgttgt gttgttggtt ttagtttttt gtgttttagg 174060 gtttttgaat atattgttgg ttgtttgtag tgattgtttt tgtttgttgg gtttgagttt 174120 ggtttatttt ttttattttt ttgtgtttag tttgaaggtg tttttttgag gtagtttttt 174180 tgatttggtt ttatgaattg taggttttgt tttgttattg gttttttttg ttatatttgt 174240 tattttttgt gttttatgtt tattgatgtg gttttgtatt tgtgtagttt tatgagggta 174300 aggattgtgt ttggttttgt tttttatggg attttagtgt taagtttata gggagtattt 174360 aatgttgaat gaatgaatga gtgattggta agggaggttt attttgttat gttgggggtt 174420 aaaggttgtt gggtggatta tatgggtgag gttgggtggg gagggaagta gagatgattt 174480 tttggaagaa ggggtaggag gtggggaggt gggtgtgggg tgttgtataa ggatggtaag 174540 tgtttttagg ggtgataagt taatttagag tattaggtag tagaaaaagg ttgatatttt 174600 tatgttttat ttttatttag ggagaggtta ggtttttggg aaagttagtt ttttgttgtt 174660 aggagagttt taagggaagt tttattagtt gttgagttgg ttatagtgga aatttatgtg 174720 gtgggtggga ggggtttgag gtataggggt ttgggtggtg gttttaggat ggagatttgt 174780 gtttagatta tgaggggtgg ttttagggat gattattttt aaataggaag tagataaagg 174840 tatagatggt agaagtggag gtagagaatg ggttgtaggg gtttttttag agggagagtt 174900 gagtaagggg ataggttgga aatatttagt ttttatggtt tgaagtatag atagttggtt 174960 ttatatgtag gttgggtagt tatattattt agaataaggg gtatgtttgt agggtaggtt 175020 ttaggatgtt ttgggttggt tttgttatta gtttagaaag atggtttagg tttttttggt 175080 agggagtatg tttagttagg ttttgggtag gagttgagat tttttggttg gtttgagagg 175140 ggatgattga gtgtaggttt agtttgggat ttttttattt ttttttgtta tttagtggaa 175200 ttagttgggt gtgagaaaag aagagaagtg aattaagagt ttagagtatg aggttggatt 175260 agtttttata ttatatgtaa aaattaattt aatttgtatt aaagatttaa atttaagagt 175320 taaaattata aaatttttag aagaaaatat aggggaaaag ttttttgatg ttgtatttgg 175380 taatgatttt ttggatatgg tgttaaaagt ataggtaata gaagaataaa tagataaagt 175440 ggaatgttat agaagtttaa aatatttgta tattagtttg ggtgtggtga tttatgtttg 175500 taattttggt attttgggag gttgagatgg gtggattatt tgaggttagg agtttgagat 175560 taatttagtt aatatagtga aattttgttt ttattaaaaa tataaaaatt agttgggtgt 175620 ggtggtgggt gtttgtaatt ttaattattt aggaggttga ggtaggaaaa ttgttggaat 175680 tagggaggtg gaggttgtag tgagttaaga ttatgttatt gtattttagt ttgggtaata 175740 gagttagatt ttattttaaa aaaaaaaaaa aaaattgtat attaaagggt attaataatg 175800 tggggagaag gtaatttatg gaatggtagt aaattatagg ttagatatgg gattagtatt 175860 tggatattaa tttatagatt ttttaatatt tagtaataat aattatttaa attaaatata 175920 ggtaaaggat ttggatagat atttttgtaa gaatatgtgt aaatgagtaa taaatatgaa 175980 aagatgttta atattattaa ttattgggga attgtaaatt aaaattataa ggagagattt 176040 tttataatta tgagttttgg gtaggtagga agatgtttgg tggggagttg ttggttttat 176100 gttgttttta gaatttttgt aggggttaag tttgattttg atattttatt aggagtatag 176160 aaatgagtgg aaaaggttaa aggttatttt aaagggttag aggggtttag taaggagttt 176220 gggatatgga attatgttgt gtatttagat atatggggat aataggggga tgaaaggtgg 176280 tttttaaaat ttatatttat tttagagttt atgaatatgg tttatttgga aaaagggttt 176340 ttgtagatgt tatgaagtta aggattttga gatgggatta ttttgggtta tttagtgggt 176400 tttaaatttg agaaagattg tttgtatgag agatagatag ggggagattt agggtataga 176460 aggaggtttt gtgataatgg aggtagaggt tgagtggtgt ggttatgagt taaggaatgt 176520 taagggtttt gggagttgtt agaagttgtt agaggtgaga agtaggtttt tttttggagt 176580 ttttggaaag aattaggttt gttgatgttg tgattttgga tttttggttt ttagaatggt 176640 gagagaagaa atgtttggtg ttttgagtta tttagtttgt ggtatttggt gatggtagtt 176700 ttaggaaatt attataggga ttagagtttt tatggggttg ggtaggaagt gggtgtagag 176760 tgtgttaggt taggtttttt attttggaga tggaaaagta gagttggaga ggttgagatt 176820 ggataggtat tgagtgttta ggggtaagaa tttttagggg atggtagagg ttattgggga 176880 tagtatagtg agggatagga gggaggggtg agggttgagg tattgttttt taggaggttt 176940 tggttttttg tttattgatg atttaggaat tttgtaagag gagttgggtt ttattttgtg 177000 ttgtattgta ttagatggat tttggtgggg atagatgttt agtgatagtg tggttaagtt 177060 ttttttagga ttttgggttt gtatttatga ttatgtatag atggttattt tttttgtttg 177120 tagttttttt ttgtggtttg tttttagttt tttagtttaa tagagttttt tagtggaaag 177180 tttttttttt ggagattttt tttttgttga aatataagtt tttggaataa gataaaattg 177240 tttaatttgt aaaagttata aagttgtttt agaataaaaa aaaagttttg atttttggtt 177300 ggaaggagtg gttttttatg ttttagtggt tagttattat tttatgattt atgttggttt 177360 tgttgataaa ttttttagta tttttttagg ggaaggttat agtttttagg gagggtggga 177420 gagtatttag gtttttgttt ataaattaga ttggagttag atattgttga gggagggata 177480 agagggtagg ttttggggtt tttaagtttt ttttggggtt ggtagattat tgtggattta 177540 ttagggtagg attatttttt tttataaatt ttttttgggt agttgtaggg tagtttgagt 177600 tggatatgtt ttatatgtta gtttagtggg gtatgaggta tttatagtta tgtttggaag 177660 ttagtgggtt ggtatttgtt gggtaggttt ttgttatata ggtatagtgt tttttttatg 177720 gttttttttt aggttagagt atgtttgggg attagagtag tttttgtagt ggtttgtagt 177780 ttgataatgt ggtgtgagtt atgttttgta gagaagaaga gttttttagt gagggaagag 177840 gtgtttataa aatttaggat atgtgtagaa atttgtagga ggtgggggtg ttgtttaggg 177900 gttgtgttgt ttttattttt tattttgtag atgatggaat tgtggtttag agttgttaag 177960 tggtttgttt aaggttattt agtagggata ggaaggaagt tattttttta gggattgtgt 178020 gggagtttag tgataattaa agattagtgt taaagtttgt ttaggatgag aattttatta 178080 agggaaatag ttttgggatt gttgtgttta tttggaaggt agttagttta taattgagtt 178140 tttaaaaatg tatgtttttt tatatgaaaa tatatttgaa tgggattttg tagaaagtat 178200 tttttattaa ggtatagttt gaggggaggt ttttgtttta tttttggttg tgttgttttt 178260 agttaagggt agtagggatt agagtggttt ttggggtata gtattggttg tttttaaaga 178320 gtgttttgtt tagtttatga aaagtttgtg ttttgtgagt ttgggagggt gttattattt 178380 ttagtttttt agggagtatt atttttaaat ttatgttttt ttgtttagtt tttagatttt 178440 ttgttggtta tttatttggg ttttggttag attatttata aagtgaaggt tgaatttgag 178500 gttttttgag gtttttgtta gttaggtggg tggagtgatg tttttttggg gttggtggtt 178560 taggaggtag gggatttatt gtggtttgtt taggttgttt ggtggggtgg ttattttgag 178620 gatggtttta ttgtgtaagt ttgatgaagg ttttttttag tgttttttgt tttgtggttt 178680 ttgttgggtg gagagtagga tgttgggttt tatatttatt tgttttagtg ggtttgagtt 178740 tttgagttta aatagataag atgtagtttt attgttattt aagttttttg ttgttttttt 178800 tggttttttt ttgaggtttg tttgttgtgt ttgattgggt gtgtttagtg gtataatata 178860 tatttgtttt attagtttta atgtgataat taagatgtgg ttttgaggtt gggtgttgtg 178920 gtttatgttt gtaattttag tattttggga ggttgaggtg ggtggattat gagattagga 178980 gattgagatt attttggttg atatggtgaa attttatttt tattaaaaat ataaaaaaat 179040 atggtgggtg tttatagttt tagttgtttg ggaggttgag gtaggagaat ggtatgaatt 179100 agggaggtgg agtttgtagt gagttgagat tgtgttattg tattttagtt tgggtaatag 179160 agttagattt tgttttaaag aaaaaaaaaa aaaaagatgt ggttttggga gtagtggtgg 179220 aggggattat atgttttaga gaggagttat tgagatgggt tttttttttt taggtttttt 179280 agggattttt taatatatat atagtggtaa ttaatagatt agggtttaag gtatgtaggg 179340 gttgatattt ttagtgattt tttgttttat ggtttgtagg ttattttaga atatttaaag 179400 tttggagttt ggtttagtta ttttatgttt tttagtgttg ggtttagagg gtggtatgag 179460 tggtagaaat tgttattatt gttaattatt gatgatggtg ttggttatgt gagatggtag 179520 ttatggtatt gtatgtgagt gaagggatta aggaggttgg gtttgggagg gagggtttgg 179580 aaagttgggg tgaattaaag gtaggggagt tttttttttt tttatttgtt tgtttatgtt 179640 ttgatgggtt tgtgtttgtg gtaagggggt tgttagtgtg aatggatata tgtatatata 179700 tgtatatata tgtgtatata tatgttaggt ttttttgagt gttgggagtt ttttttttta 179760 taattaattg ttaggaaggt atagaaatgt tattttaggt aggagattga ggtagttttg 179820 aagatagatt ttggttggaa gtaaaaaata aattatatag tggataaatt aattattagt 179880 taggtttaag tgttgttgtt ttagatttga gttagggggg taggtttttt atattttttt 179940 aaggttttgg tgttaatagt tttagtattg atagtggtta tgatatgtaa gaatggtata 180000 ttggaaaatg aaagggaagt agttaggaga gaggagagtt gagtttaaat aaaagttaga 180060 tttaggagag tttagttttt gagatggagt ttattttatg agtttggaat tgttaaaaag 180120 aaaagaaata tttttgtgaa aaatgagtaa aagtgttttt tgtatgttta tttttttagg 180180 tataaataaa gttttgagtt tagggtagtg gggggtggtt gatggggagg gggttgtttg 180240 tgtatttgag atttggtttt tttttatttt tatggatata tttagtagtg gtgggagttt 180300 tggtgttttg tttagaggtg gttttttttt ttttattttt gttgtttttt tttttttagt 180360 tttttttttt tttttttttt tttttaaaaa tattttttgt ttggtttaat ttttttaatt 180420 tgttgtaatt atgaatgtat ttgaattatt atatttttat gtgttgatta tatgtttgtg 180480 ttttaaattg aagtagtatt gtttttttaa aatgggagga aaaagggagt aaaggagaga 180540 aatttaaaaa taggaggtag gagagagggt ttgaagtggg ttttgaggag tttggtagat 180600 tattgggttt gtttgtgaga gttttagagt tttggttgtt tggtttggtt ggtggttgta 180660 gaggttttga gtgtggtttt tggtagtttt ttttttttat tttttttagt ttttgttgtt 180720 ttgaggtttg ttgttttttt ttaatattta tttggagatg tttaatttag atttttggaa 180780 attaatttat agagttaaat ttttgatgat ttttaaagtt ttttattttt tttgttttgt 180840 gatgttatga tttttttggg tttaagggtt taaaaagttt agtttttgtg tgtttgtttt 180900 gttttttttt gttttgggtt ggttttagtt tttttttatt ttgtatttta atgtggttgg 180960 gtaggaggaa tggttgtgtt ttaggttagt gtgttgagaa aaggttttgg agtatttgtt 181020 taggaggaat tttgagaagt tatttttttt tgttttatta gtttgtagtg atagaggtag 181080 ttgttgtttt tgtttaggta gagagggtga atgggatggg gattttttgg aagattttta 181140 ttatatatgt atgagttagt gagtttttag ttgttttttg ggagggagtg agtttttttt 181200 tttgggaatt tggggtttta ttgggggatt agtgttgttt tttattgttt atttggggtt 181260 tttagaggtt gtttatttat ttggggggtt tttattagta tatggttagg gtttatgttg 181320 aggttaaggg tttagtagag taggtggggg tttataatgt gggtttttgg ggtgggaatt 181380 aggggtattt tttttgtttt taagttttat tttaagggtt tatttaaatt tgagatatgg 181440 aggttggttt tgttggttta agtttgttta aagagaatgt gtgtttgtgt taaggttgag 181500 aatttaggta atttttttga aaattttaga ttgttagttt ttgttgagaa agggaggatg 181560 tgtggttgta ttatggaagt ttttttgttt ggttgtatag ggttggtata agatagtttt 181620 gttttttaga taaaatattt tttagtttgt gttgtttttt aaggttttta ataaatttat 181680 aatatttgta tttttttatt ttgatatatt ttgtaggttt ttgagtttat aatttttgtt 181740 ttatagagtt aggtgagtta tttgtgatta ggtgaggttt atgtatagtt tttggttaga 181800 tgatagagtt aaaggttttg aagtgttatt ttaggttata gttttgtttg ttttttgttt 181860 gggataggat tttaaatgta atttttttgg tagaaaggat atttttttgg ggggtgggga 181920 ggattatttt tagttttttg ggagatatta agtaattatt tttttttaaa gagtttggag 181980 gatagtttta taggtagtta gatagtgagg gaggtgggga tagtatttta gttgaggtgg 182040 gaggttgggg aggaagggag ggattatagt tatgagagaa ggttgaataa tggttttagg 182100 gatagtatgt tttaattttt agatttgtaa atgggatttt gtttggaata agagtttttg 182160 tatttgtgat ttagttgtag attttgttgt ggtgagagta ttttggatgg tttaggtggt 182220 ttttaaaggt agttttggtg tttatataag atgggggtag agggagattt gatatagata 182280 gggatggtta agtggagatg gggtttggag agatttgtag atgttggtgt tgaaggtaag 182340 ggttatgtag ttataagtta agggatattt atagttatta gaggtttaaa ggggtaggtg 182400 atgaaggtag tggtttttaa tttttttggt atttgggatt ggttttaggg aagataattt 182460 ttttatagat tagggagtgg ggagatggtt ttgagatgat ttaagtgtat tatatttatt 182520 attttatttt attttatttt attgagatag agttttgttt tgttatttag gttggagtat 182580 agtggtatta ttttagttta ttgtaatttt tgttatttgg gtttaagtaa tttttttgtt 182640 ttagtttttt aagaagttgg gattatagat gtttgttatt gtgtttggtt aatttttgta 182700 tttttagtag aaatggggtt ttattatatt ggttaggttg attttgaatt tttgattttg 182760 tgatttgtta gttttggttt tttaaagtgt tgggattata ggtataagtt attgtgtttg 182820 gtttttattt tttatttttt gagatagagt tttattttgg gattataggt gtgagttatt 182880 gtatttggtt ataagtatgt tgtattgatt gtgtatttta tttttattat tattataata 182940 tataatgaga taattatata atttattata atgtagaatt agttggagtt ttgagtttat 183000 ttttttgtaa ttagatggtt ttatttggtg gtgatgggag atggtgatag attattaggt 183060 attagatttt tataagaagt atgtaattta gattttttat atgtgttgtt tataatatgg 183120 tttatttttt tataagaatt taatgttatg gttgattaga taggaggtag agtttgggta 183180 gtaatgtgag taatggggag tgattgtaaa tatagatgaa gttttgtttg tttgttagtt 183240 atttattttt tgttgtgtag gttagttttt aataggatat atggggttgg gaatttttgt 183300 tttagagttt ttagagggtt atgtttagtg gatattttga ttttagtttg gtgattttga 183360 ttttggatgt gtggtttgta gagttgtgag aggatggttg ggtgttgttg tgatttagtt 183420 agtttgtggt tatttgttat agtagttgta ggaaattgat gtagtgttat agatggagtt 183480 agggtttagt ttattggagt tgttttttgt tattttattt ttttttaaaa tattgtgtta 183540 agttaattat taataattat tgattttgat gggtaggaat tgtagaggtt ttttggtttg 183600 tttttttaat ttttttttta attttgaaat aatatttttt gttggttttt ttgattataa 183660 atgtaatatt tttttttgta ttgagtttag aaataagaga aaaagtaaaa agtagaaatt 183720 ttagttgggt aaggtggtat gtgtttgtaa ttttagtatt ttgggaggtt gtggtggaag 183780 gattgtttga agttaggagt ttgaggttgt tgtgagttat aattgtatta ttgtattttg 183840 gttgggtaaa aagagtgaga ttttgtttta aattaaaaaa aaaaaaaaag aagaggaaga 183900 aaatttatta attttatttg agatttttta tatgaatttt tgttgtgggg tagggaagtt 183960 taggaaggtt ttatgaggtt ttgatttagt ttggttggtg gtgggaattt gggaatagtt 184020 ttgagtgagg ggttgggtta tgattgagtt tatttattta gttatttttt gtatgttgtg 184080 tatattatgg gtttgatggt tagggttgga gtatttgttg agtatagttt tgatttttag 184140 ttttatttag tatggtttgg tttgaggttt attttttttt tgtgtttgaa aatttaaata 184200 ttttggttta ggtgggggat tatttgaaat ggaaaatttg gtagtattga ttggttttga 184260 agaggtagga gttagttatg agttggttgg gaggtgagtg tagaggtggt gaggtaaggt 184320 tagtagaggg tgggggaggt gagggttaat tttttattgt gtatggtgta agtattaagg 184380 gggtatttta ttaggttagt gtagatttag gtttttgtgg tggatttttt gtggtttttt 184440 tttttagagg aatattgaag aggtttttgt ggttttgttt tagatttaga ggtatatttg 184500 tatattaaat gtattgagta attttatagt gagggagttg ggtttggttt aatttatttt 184560 tttttaaatt ggattaaagg ttgttgtttt aggaaggtag ggtttttagg tttatggttt 184620 tgggaaattt tggttgtgtt agtttatgag tttagttttt agttatttta gtttgtttat 184680 attttggagt gggtattgtt atttaaaagt tttttttaga tagtttttag ggtggtattt 184740 ttgtttttta ttttttatag atttttggtt atttttttgt gatattagta ttattggttt 184800 atagtttttt ttaattgtaa agtggggttt agtggtatag gttgggtttg gtagggtggg 184860 aaggaagagt gaaggttatt ttgtttttaa tagtattggt tgggttttgg aaaggttgga 184920 atttatagat aggaaggaag tgttatattt atttaatttg ttttgtgtta gttagggggt 184980 attttgtaga aagaagttag gtggttgtgg ttgggtgtag tggtttatgt ttgtaatttt 185040 agtattttgg gaggttgagg taggtggatt ataaggttag gggttttaga ttagtttgat 185100 taatatggtg aaattttgtt tttattaaaa atataaaaat tagttgggta tggtggtgta 185160 tgtttgtaat tttagttatt tagaaggttg aggtaggaga attgtttgaa tttgggaggt 185220 ggaggttgta gtgagtttag attatgttat tgtattttag tttgggtgat agtgtgagat 185280 tttattttaa aaaaaaaaaa aagaagttag gtggttattt tttagttttt ggtttggttt 185340 aggaattgtt ttttttttaa gatgttatta aatgtttttt ttattaggaa gttttttttg 185400 gttgtttttt ttatttttgt ttttgtttta gaatatggtt tggtttttat ggataatttt 185460 gatattagag tttaatagag attttttttt ttatggaaat ttatatttta aattgaatat 185520 gtgtgtagga taagtttttg tttttatgtg aaataaaagt gaaaggtgtg gattatttgt 185580 ttttttttat ttttttttat aataatttgg gttttatagg ggtttagtag gagttaggtt 185640 tagtttagtt gttttaggtg tattattttg ggtattagtg tttttgtttt tttttatgaa 185700 gtatagtttt attttttggt atttagtggg gaggggatat atattaggta ttttttaggg 185760 tggattgtgt tttttatatt aggttaggag gttttggggt tggtttagtt atttagaaaa 185820 gggagtaggt ggtttaggtg atattgatgt gggtagtagg ggtttttggg aaagggtttt 185880 tgtaggattg gttttatttt gttttaggag tatatattgg ggaagggtgt tgtgtggagg 185940 tggagagaat gtatttttgg ttgaaagtat gttttttgat gttttgggtt tggatttgtt 186000 gttatttttt atgttttttt atttaatata tgttttagta aattttttat gttgatgagt 186060 gttaagttat agaggatgta taattttttg ttttaaaaag tgattttttt tgttgggtgt 186120 ggtggtttat atttgtaatt ttaatatttt gggaggttaa agtgggagga ttatttgagg 186180 ttaagagttt aagattagtt tgggtaatat agagaaattt tatttttata aaaaaaaaaa 186240 aaaaaaaaaa aagtttaggt atagtggttt atgtttgtaa ttttagttat ttgggaggtt 186300 gaggtaggag aattatttga atttgggagg tagagattgt agtgagttaa gattatgtta 186360 ttgtatttta gtttgggtaa tagagtaaga ttttatttta aaaaaaaaaa aaattttttt 186420 ttttgaaata gggttttatt ttttttgttt aggttggagg atagtgatgt gattataatt 186480 tattgtagtt ttagtttttt gggtagttgg aattataggg ttgtattatt atgtttagtt 186540 aattttttgt atttttagtt aagatggggt tttgttatgt tgtttaggtt ggtttggagt 186600 atttgagttt aagtgatttt tttattttgg ttttaaaagt attgggatta taggtatggg 186660 ttattatgtt tagtttgaaa atattttttt taagaattag ttagttatgg tggtgtataa 186720 ttgtagtttt agttatttag gaggttaagg taggaggatt ttttgagttt ggtaggttga 186780 ggttgtagtg agttataatt gtgttattgt attttagttt gggggataga gaaagatttt 186840 gtttagaaag aaaaaagaaa aaaaaaagat ttttttattt attttttgtt tatttttaga 186900 tttaattatt gaagtttgtt tttttgaatt aaaaatgaag gagttttgtt ttggattttt 186960 ttttgttgat tttgttattg tatttgttag tagagttagt taagattttt taggttggtt 187020 ttagtttggt ttgtttatag ttttttaagt aagatggatt tttaggttga ggttagttgt 187080 attttttttt ggaatttttt tttatttttt attgtgtttt agattttggt tgtttttaaa 187140 taaatataat ttagttattt ttgtttttgg ggttgttgta gggtttattg gtgtaaattg 187200 tttgggtagg tttgttgttt taggagtttt tttaggttag tgtggaagga aattaagata 187260 atggggagaa gtagtttggt tgggtttaat tttattttta tatgtttgtg tttagttaat 187320 tatttgggtt gtagtttgat aggagttgga gttggtgttt tatttttaga gggggttttt 187380 gattgttttt gtagagtgag ggaggtttgg gggtgtagag gttaagggtt tttgtagagt 187440 ttgttttagg ttttttgagt ttaagttttt ttgtagttaa tggaagattt ttttgagagt 187500 gggtgttttt tattttgttt gtttagtagg tgtttagtaa ttgtttattg gataaataat 187560 gaatttgtgg atttaatgtg aagatgattt aaattagtgt ttttttatag aattttttgt 187620 aatgatgtta atgttttgta tttgttgtag ttaatatggt agttatatgt ggtagtgaat 187680 gtttgtaatg tggaagggtt attaaggtaa agagttttgt atttatgtta taatttaaat 187740 ttaaatagtt ataaatgttt agtgtgtgtt ttgttatata gatttttttt gttatttttt 187800 tttttttttt agagatattg tatttgttat taatttttta tttgggaggt aaatggagaa 187860 atgttatttt ttagttaatg taaaagaagg ttaatatttg tattttaagt tagttttttg 187920 ggtaattttt ttaagtattt tttattaagg ttagtttagt aatatttttt gattgtttgt 187980 tatgtattag gaaagtattt tgttgtggtt ttggtttgag gttatggagg atatagaaat 188040 aattaaggtt aagttgatag aaggggtgtg ataagatggt ttaaagttat tgagttagtt 188100 aggaggttta ggagtatgga agttttgttt tttagaggat aagtggtaat ttatttaggg 188160 ggggtttgag tatttagagt taggagtgta gaagtagggg gttttaggtt ggaaagtggt 188220 attagggtta ggttgggtgg tagtatgaat ttatttttga ggttttgggg gtggaaatta 188280 agggttttat gagtaagaag atttggttta ggtttaatgg aaatgattgg gtggagggat 188340 tttattattt ggtttttagt atatagggag ggaagtggta attgtttttt aaatgttggt 188400 tgtggagggg aaggagttat agtagggtag gggtggggag gatggtattt gttggtttaa 188460 ggagggatga tggaggttta attaagatat gattgtgatt ggggtagttt gtttaagggt 188520 tagtatgtag agggtgagtt gatgagattt tggtagtttg ttgagatttg ggggtgttgg 188580 ggaggtagag gttaaggtta attttgagat tttttgtttg taaatttggg tgggtggtaa 188640 ggttgatatt agagaaatag aggaagagtg ggtagttatg ggtgagagag gaagtaatga 188700 attaggggtg tttgtaagag tttaggggta aggtttttgg gtagttaaga tgttggtggt 188760 tttttttatg attagttttt tttatgtggt atatttttgt ttgtatggtt gggtatgggg 188820 tatttgtttg tttgatatat tttgagtagt tattttgtgt attgaggtaa tgtggtatgg 188880 tgttttgggg aaatagtgag gaggtattgt ataggtttta tttttttggt attttttgtt 188940 ttttggggat ggtggtagtt aaataagtga tagttaattg ttaggagagt ttggttttga 189000 tttattaggt ggagttaggt atttttgttg gaagaggtat gggaattagt ataggatgaa 189060 gggaggtagt gagtattagt ttaggttttg tttttatagg gttttttttt tatatttatt 189120 tgtgtaggtg ttttttgtga gggtagagat atttgtagtg tttgagggag attttttgtg 189180 ggtggggttg tttatttata gtggttaggt gggaggtgta ttagtgtttt gtggttgtta 189240 taatggatta tagttgtggg gtttgaaaaa atggaagtgg gttttttttt atgttggagg 189300 ttagaggttt aaaattaagg tgttagtaag gttatatttt ttagggaggt tttggggtgg 189360 ggtggggggg gggttttttt ttgttttttt ttagatgttt tttggtttgg ggttgtgtta 189420 ttttattatt tgtttttgtt tttatgtggt tttttttggt gtgtttgtgg tttttttgtt 189480 ttttttaagg atattagttg ttggatttag ggtttatttt aatttagaat gattttattt 189540 taagattttt aattatttat atttgtaaag attttatttt taatttttag gttatatttt 189600 gaggtttttg gtggatatga gtttgtgggg gatatggttt aatttaggat agaagggatg 189660 atgggggtat tggggaaaag gttatatatt ttagaggtat tggaagatgg aagagtagga 189720 tttagtgata tgggatgtta ggtagaggag ttggttttaa ggattttagt tggggtttga 189780 gggttagagg gagggaagtt taggtattat tgagatgaaa tgttttgtgt attgtgggaa 189840 atagggtaaa agtttgttgg atgtttagtt agagaggtgg ttgtttgagg tatagaaaat 189900 gagtgaatat gggagagttt attagaaggt tatttgggag ggtgtggtgg taatatttag 189960 aagggttgag aagtgtattt ttatagttta gttaaattta tttggggaaa tatatgtttt 190020 tggtagtatt agtaatagag aagatttttg gtgatgttat tagtgggtta tgggatgggt 190080 aaattttgtt tttttatata gaggaatatt tgttagttgt taaaataagt gaattaaggt 190140 tttgtggatt tatatggata agtttttatg ttgttatgtt gtgggtatag gtagggtagt 190200 tattgatttt agtgaggtat taaggatgtg atgttgatga tggtatttaa gaggagatag 190260 atttaggttg tttagttata tgatgttgat gattgtatgt aagaggagat taggttggat 190320 gtggtggttt atatttataa ttttagtatt ttgggaggtt aaggtaggtg gattatttga 190380 ggttaggggt atgagattag tttgattaat atggtgaaat tttgtgttta ttaaaaatat 190440 aaaaaaaatt agttagatat ggtggtgggt gtttgtaatt ttggttattg aggaggttga 190500 ggtagaagaa ttgtttgaat ttaggaggta gaggttgtag tgagttgaga tggtgttatt 190560 gtattttagt ttgggtgata gagtgagatt ttattttaaa aaaaaaaaaa aggagattta 190620 ggttttttag atatattatt gtttagtata gatgtgtttg tttggggtta gattttaatt 190680 tagaggggtg ggtattgtag taggagtggg gttaggatgg agaaggttat ttagggttgt 190740 ggttatattt gtaatgtttt attttttaag tgggatggtg agtatatagg tgttttatta 190800 ttttattttt tatatttttg ttttgtagtt ttaagaattt tatttttttt ttaaaaggaa 190860 agaaagtgtg tgagttgatt aaagtgttga ttatggtgtt atttaagttt ttgttagaaa 190920 tgttattttt ggtttagttt taaatataat tttgagaaga gtttttgttt ttttggggag 190980 ggtaagagtt ttagatatag gagattggtt agatgtggat ttatagagaa gttgggttgg 191040 gaggatggga tggtagatag ttgtttgggg agtgttaaat ggggaggttg gagatgttgg 191100 ggtgtttagg aatgaatttt tgtttggatt agggttttag taaaagggag gtagggagaa 191160 agaaagaagt taagaagatg aggaaagggt gttttgggtt agagtttata gaggtttata 191220 gagggaggat tttgtgtgtt agtaggtagt tttatgtaaa tttagattat tagtttgtag 191280 ttttgggatt tagtaaatta tgttttaggt ttttaagttg agttgtgatt gtggttgtta 191340 agtgttgata gtatagaatt agttagtttg agtagaggga agtaattgtt gggggaggtt 191400 gtgtttatgt agtttagggt gttaggtttt taagatgtaa tttttataag aattggggga 191460 ttttttttat ttattttatt agaagttggt taatgagagg gaaggagatg gagaggtaga 191520 ttagatgtgg agttggagaa aagtttttta gaaatatagt agtggttggg ttgtttagtg 191580 gttagtgttt aatatgattg tgatgggtgg agtttttttt aattatagtg ttgaattatg 191640 tagttgttta ggggttttta gttagagtat tatttttttt tttttatata tagttttatt 191700 ttgtattgta aggggtttta tatgtattta atgtggatat ggtatttttt ttatttttat 191760 tttttgtaaa aagttatttt ttttattgtt taggtttggt ggtgtatagt ttatgggtat 191820 tgtatttatt tttggaaggt agatttagga ggtgtttgtg ttgtttttat agaagtaagt 191880 ttaggattag aagtaggttt tgggtttaga attttgaggt tttaggtgtt agtgtggttt 191940 ggaattgttt agttttatag ttattagtta tatgtagata taagtggaaa tttatttaaa 192000 ataaataaat aattttatgt aagtaaatga gtgaataaag taaatgtaaa tatttatatt 192060 ttgagtgtgt aatagattta ggtggttaag tggttattat ataggatggt ggagtgtaga 192120 tgtatagaat agatttatta ttatagaagg ttttattaga tggagttggt ttagagtatg 192180 gaggtggtgg ttttagatgg gtatatgttt ttgtttttgt aggtgttttg ttttggtagg 192240 atggttgttt tattttgttt tgaaggtagt tttggtttat aggtgtttta tttgtgtgga 192300 tttgattttg ggtttgtgtt ttttggtaat tttgtttttt ttagaatggt taatttatga 192360 aggtatagtt tttgtttgtt tgttattatg atggtagtta ggggtttggt atttagttgg 192420 tttttagtat atatgtatag gtgattatgt tatttttgtt ttttttagag ttttttgttt 192480 tttaggggag gtaagtttat ttattgttgt gatttattat tttttttaaa tagaaaagtt 192540 attagatggg tatttgtttt agtttggttg ttggaagtga tagttaagaa taatgtaggt 192600 ttttagaaat agaggtatta gtatggttat attggggtta ggtaggggag attagggata 192660 tttagtgggg agaagatgat gtgtagattt agttttgggg ggtaagggtt ggaggtagag 192720 ttttgatttt tttgttttat ttttttgttt aggttgtatt tagtgttggt agagtttttt 192780 taagtttata agttgtaatt tgtgttttgg atggttagtt ttagagtttt gatgggtgta 192840 tttgtttttt ttttttattg gttagtgtgg aaaattttta aatatatgga aaaagtataa 192900 ggagtagtat agtgattatt gttagaggtt tatttatttt tttttagata atattggatg 192960 tatttgtttt attttggagt attttttatt ttgtaaggtt gtagggagtt tatagatatt 193020 gaattaatat tgagaggttt atggttaaag ttatttgttt atggtatatt tgttttttta 193080 gtattttaaa ttaaattatt tagttttatt tattttttgt tttttttttt gttttgtata 193140 tatgggtttg ttttttgagt ttgggggtgg ttgtttttgt ttttataagg attattttta 193200 gtagggtagt gttgataggt ttggaagtta tttgagttta aagttgttaa agattgtgtt 193260 tttttgggaa atgggtaagt ggttttattt atttagggaa gttaggtggg gaggtaggtt 193320 ttagattaga atgaagggat tttagtataa atatatttat gagttgggtg gggttagagt 193380 ggagtgagtt atttatttgg gttattggag ttattaagtt tttggagttg gttattggag 193440 gtttgtgtgt tttttaaaga tagagataaa gggtaaaggt tatataaggt tattggtgtt 193500 ttttttttgg gtggatgatt aatattagga atgtttttgt ttttgttttt gttgtgagtt 193560 ttagagttag aaatggggtt tatttgggga tagaggtttt atttttttag gtaattttgg 193620 atgttggagg gatgatagtt attgttgttt ggttgttgga ggggttttgg gttaaatttt 193680 tatatatatt tttttttaag ttttattatt tttgttttgt agataaggaa tttgagtttt 193740 tatagagtgt tatttttttg tggttatata gtgaatgaga gttgtatata ggtgagttta 193800 tgtttattag attttaagtt gggttgtatt taagtgtgtt tttgttggat ggagtttttt 193860 ttttttttta tgtttatttg ttttatgaat tagggttttt ttatattagg gtttataatt 193920 tatgggtagt tttgatttag ttttttttat ttttagggtt gggtgtagtt gggttggatt 193980 tggggatgga gtgggatagg ttatttttat tttttgtttt aggagggaat aaaaatagaa 194040 ttttagatta atgtagtttt ttgtggtatg tgtttttttt gtttatatat aggttttggt 194100 ttggggttgt ttgttggaga ggtttatggt aggtaagttt taatttgagg agatttgttg 194160 aggtgttaag ttaagtaaat ttgaaaggtt gttaggagga gtggttttgg gagtataggt 194220 ggttatttta ttgttgtaga gtatggtatt ttggggatgt tttttgggta atgttatata 194280 gttatttttt agagagtttt agggatatat aattagttta gttttattaa tagtgagata 194340 agggattagg tagatttaga tatttttttg tatttgatta ttatgttggt tgttggttaa 194400 agatgttagt ttttttttgg aattttttag aaaggttttt gtagtattta tttatttatt 194460 tatttattta tttattttat ttatttattt atttatttat ttatttatgg attttattta 194520 ttttattatt tttttatata tttatttatt tatttattta atttatttat ttagtttttt 194580 atttatttat ttatttatta atttatttat ttgtttattt aatttattta tttattaatt 194640 tatttattta ttatttattt atttatttat ttatttattt atttttttat ttatttattt 194700 attttttttt ttatttattt tataatttta tttttaaatt gtgattagat ggaaatgggt 194760 gtagttagtt tgtttttaaa ggtttagagt ggaggtagag tgaattgttt atttggtttt 194820 tgtgtttagt agtttaggtt tgtatatatg ttttataatt ataggatatt agatttagta 194880 attggtagta gaatgagtat agtgtatttt ttgtggaatt agtattgata gggtatttat 194940 ttttattaag tttgagtttt tttggtgttg gagggaattt ttagatgggt tttaatttta 195000 gttgaattta ttttttaggg aaagtaatat tgtgagaaat gtgtgtgata taaggtttta 195060 aagagggtgt gggttgtgat ttttggagta attagggagg ttttatggag gagatgagga 195120 taaagttgag ttttgaagga gggattggag gatgttgagt agggatattt atttttgttt 195180 gtgagggttt gatggtaggt tgtgagttgt attttagttt tgatttattt aatttataat 195240 tttagtaggt aggtgttttt gttttatttt atagaggagg aagtgaggtt tagggttggg 195300 taaattgttt aaggttgtat agttgtggaa tttattttta gtatttttag tttgttttag 195360 ttatgtttgt gattttattt agtatttttt ttttggtgtt tatttatttt gtttattgtt 195420 aagtaataaa aattttatta ggaaaattta ggggtttttg gttagttttt ttagatagaa 195480 aggtagattt tggtgtagat ttttaggaag taaggatgga agggttagta tttgtttttt 195540 agaaatgata gtttttttaa gattaggaga gatggtttag agtgtagttt tggtgggttg 195600 tttaggatta ggaggggaga ggagtgggga ggaggatgaa ttttattttt aaggttgttg 195660 agtggtatat agtgagtttg gattttttag ttttagttga gtttattttt atgatggtta 195720 tgagtatttt ttttatatat ttgattggaa gttgtattgt atataatgta tatggggtta 195780 ttattttttg ttttatatat ttttatgtat atattattag tgtattattg ggatattttg 195840 ttgtttgggg ttgagagtga attagaattt tgtttataaa tttagtatat tttattgtgg 195900 aaataatggg gggtaaggag gggttgttta gtaaagaata ggatatatgt ttttgaggat 195960 ggagttattt ttggttgaga tatttttgta ggggatgttg gtgataaagg ttgttttatt 196020 tttttttttg ggttagatgg atattatttt tgttttttgt tttttagtat taggtaaaag 196080 gaaaatagaa gaggttttat ttaggttaaa tattttaggg ttttttattt gtaggaaata 196140 tgttggttta ttttttttaa atttagtatg ggggtggaga aatggtgggg aaaatagtat 196200 ttgttttaga ttttttgggt ggagtttttg ttttatttat attgtttatt tttttgattt 196260 tttaaaatgg gtatttggtg tttggtagtt tttggtatag agaagatgta aagtaaattg 196320 tttataagaa gggggtgagt gtagtttgag tattttttgt ttttgaataa attgttaggt 196380 ttagtgtagt tgttgttgtt attgttgttt ttaggaaggg atttttggtt atgagtggtt 196440 ttagtttagt tttttggatt taattattta ggtttgtgtt tgagtttagt aaagaggtag 196500 ttagaaaagt ttttaagata tttaatgatt ttgtggtttt agttgagaag tgagttattt 196560 ttatgtgatt ttaaaataaa atatatttag aaggagagaa gataattgaa atttagttgt 196620 ttggagttat tttagatgaa agtatttgag tttttgggag gtaaaggagg taggaaagtt 196680 tggagttaga tgattagaat ttgaatgtag attttgttag gtttttgttg tgggttttgg 196740 gagatgattt ttattttttg agttttagtt tttttgggga tagagatggt gtttatttat 196800 aggttgtttt gagttaatga ggttatatgg tgtaagtatt agtatagtgt ttggtataaa 196860 attaaaattt aataagtgat attattatta ttattattat tattattatt tttgagatgg 196920 agttttgttt tgttatttag gttggattgt agtggtatga ttttagttta ttgtaatttt 196980 tgttttttaa gtagttgaga ttataggtat ttgttattat gttttggtta atttttgtat 197040 atttggtaga gatagggttt tattatgttg gttaggttgg ttttgaattg attttaggtg 197100 atttgtttgt tttagttttt taaagtgttt ggattatagg tgttagttat tgttatttgg 197160 ttgtgatatt attataatat taatattata atagttggtt aggtatggtg atttatgttt 197220 gtaattttag taatttggga ggttgatgtg ggttagttat ttgaggttag tttgagatta 197280 gtttgattaa tatagggaaa ttttattttt attaaaaata taaaaattag ttgggtgtgg 197340 tggtatttgt ttgtaatttt agttatttgg gaggttaagg taggagaatt gtttgaattt 197400 aggagatgga ggttgtagtg agttgagatt atattattgt attttagttt gggtgataga 197460 gtaagatttt gttttaaaaa ataataataa taaataaata aaatatattt tgatgagata 197520 tggtaaaaga tagtagaagg taggagtttg gggatttatt atgggttggt gttttaagta 197580 gaaagaaatg tagtgtttat aagttagaga gtagatgttg aagataggag atgagtgggg 197640 ttttttggtt ttggagagga aagggtgagt ttaggtagaa agagtaaatt tagggtgttt 197700 tgtgtagtgt tttttttgtg gaattagttt agggtattag tagtatagtt tttttttagt 197760 agtggagatt aggttaattg tttagtgttt tttttgtttt tttgttttaa ttttattaag 197820 tatagttttt ttttgggtat agtagttttg taggggtgga tattgattta tgtatttagg 197880 agtttagagg tttttttttt tttatttatt tatttagaga tggagttttt ttttgttgtt 197940 taggttggag tgtagtggta ttaatttggt ttattgtaat ttttattttt taggtttaag 198000 tgattttttt gttttaattt tttgtgtagt tgggattata agtatgtatt attatgtttg 198060 gttaattttt gtatttttag tagagatggg gttttattat gttggttagg ttggttttga 198120 atttttgatt ttgtgatttt tttattttgg ttttttaaag tgttgggatt atagatgtga 198180 gttattatgt ttggttaggg gtttttttta atggattttt tttaatgtat ataatttggg 198240 gaatttagat ataagaaaga tatagagtat gaaggttttt tattggtttg tttattttta 198300 gaggtggggt tttaggtggt ttaggttggt tttaaatttt tggttttaag taattttttt 198360 gttttggttt tatgttggga ttataggtat aagttattat gtttagttat tttttttttt 198420 atttgggttg ttatgttaga atttggtaag ttataagatg gaaatgttta aataggtatt 198480 tagaatttga gtagatatta tttgatgtat tattgttgtt attttaatga ttgaaatgta 198540 tttattatat ttgttttttt aaaggttatt ttagattttt atagatttta tttgtgatgt 198600 aagatagtta ttttaaattt ttttgtgggt ttgaatagat tagatttttg aatttttggg 198660 tagagtaggg atggggttgt tttagaggag ggtgatattg ttatattttt gttttgtttt 198720 tgtgttgata atgaatgagg tttggatagt ttttttttta ttaaaagtta tattttttta 198780 aaaaggagtt ttttaggatg aggtgttatg ataatttaat tgtgtataaa tatttatttt 198840 taataatgat agaagttatt tatagaaaag aatttatttt tggttgggta tggtggttta 198900 ggtttgtaat tttagtattt tgagaggtta aggtaggtaa attatttgag gtttggagtt 198960 tgagattagt ttgattaata tggtgaaatt ttgtttttaa tgaaaatata aaattagttt 199020 gtatgtttgt aattttagtt atttaggaag ttgaggtaga agaagtattt gagtttgaga 199080 ggtggaggtt gtagtgagtt gagattgtgt tattgtattt tagtttgggt gatagagtga 199140 aatttttttt taaaatatat atatatatat atatatatat atatatatat atatatataa 199200 atttattttt attttttttt ttgaaatttt tgagagaggt taggtgtagt ggtttatatt 199260 tgtaatttta gtagtttggg aggttgaggt gggaggatgg tttgaggtta ggagttggag 199320 attagtttgg gtaatatagt aagattttat ttttattaaa aaataataaa agtttaaaaa 199380 gtttttgaga tagtttttgg ggaaaggtgg gttatggaga tttttatttt ggttatttgt 199440 gttttttttg tttgtttttt tgtggttttt ttttattttg agtttggggt gggggtggtt 199500 tgagtttagg atgggggtgg tttgagtttg gggtgggagt ggtttgagtt tgggataggg 199560 tggtttgagt tggggtgggg gtgttttaag tttgggttgt gggtattttg agtttggggt 199620 ggggatgttt tgagtttggg gtgggggtgt tttgagtttg ggttgagggt ggtttgagtt 199680 tgtgttgggg gtggtttgag ttgggatggg ggtggtttga gttgggatgg gggtggtttg 199740 agtttggggt gggggtgttt tgagtttggg atgggggtat tttgagtttg ggatgggggt 199800 gttttgagtt gggatggggg tgttttgagt ttgggatggg ggtggtttga gttgggatgg 199860 gggtggtttg agtttggggt gggggtggtt tgagtttggg gtgggggtgt ttaggatgta 199920 taggttttat tttttttttt tgaggtttag tttgtttata ggagttgtga agggttggat 199980 taaagttaaa ggtttaaatt ttagatttat ttttagattt agtggataat taaaatattt 200040 aagtttattt ttaaaggaag ttgagataag gagataatgg ttattttttt tttttttttt 200100 tttttgtttt tggtttttgt tatttggagt tgtgttttga agaggtatat tgggtattag 200160 gtttttttgg ttttgttttt attttttgtt tagatataga ataatttttt tttattttta 200220 aggttgatat gtggggttgt ggattaaagt taatttattt atttatgagg ggagtaattt 200280 ttttgtttta ggaatttgtt tttataggag aataaatatt gtagaaggta ttgtttttag 200340 tggtggtgta tgtttgtaat tttagttatt taggaggttg aggtagaaga attgttagaa 200400 tttaggaggt ggaggttgta gtgagttaat attatgttat tgtattttaa tttgggtgaa 200460 aagattaaga ttttgtttta aaataaaaaa agaatagtat tttgtgttaa ggttaggggt 200520 tttagttatt ttttttgtga agtggaaggg gtattattag tttttgtgag aaggaaatag 200580 tttatttaat tataaaatgt taattaaagg aggtagtata ttggttttgg tgtggtgttg 200640 ttggtttttg tttggggtag gaggagggtt gggggagagt taaaagttaa agaaggttta 200700 tggaggttgt tttttttttg gtgattagtt ttttttttga tggtaagttg ttaatagtat 200760 ttggttttta ggttggggaa ggtgagatta gtttatattt gtttagggtt ttgttttgtt 200820 tgtatgggta gtaggtgttt attttgttag atggttttgt ttattatagg gtattagtgt 200880 tagttaagga tttatagagt ttttttgtaa aggtttatta gtgggtattg ggattttggg 200940 ttttatttat atagggtttt tatataaaat ataggatgtt tagttaaatt tggattttag 201000 ataaataatt aataattttt tgaagagata aggattttgt tgttttattt aagttggagt 201060 ttagtggtat gattatggtt tattgtaatt ttgaattttt ggatttaagt aattttttaa 201120 ttgtagtttt ttaaagtatt gggattgtag gtatgagtta ttaaggttag taaataatga 201180 attattttta ggtataagta tattttaagt ttgttgtggg atatgtttat attaaaaatt 201240 aatttttgtt tatttgaaat ttaaattgaa tttattgttg ggggagataa tggagtgatg 201300 gattgataga ggagtataga gatagttttt ttaaattttt agttgattaa agtttggttt 201360 ttagtttttt tgggttttta gagatgtatt aagggtggaa gtgattagga gggagataaa 201420 aatattgaag tttgagtgtt agtattgagt tgtgtggttt tggataggat tgtttttttt 201480 ttgagtttta gttttatatg ttataattgg ttaataatag ttataaagta tttgaagtta 201540 atggttggga gtttgtttta ggaggtaggt attattagga tgtagagaga gtgaggagtt 201600 tttaaagtta gtttaggtta ggtatagtag tttatgtttg taattttagt attttgagag 201660 gttgaggtga gagaattatt tgagtttaga agtttaaggt tgtagtgagt tgtaattgta 201720 ttgttgtatt ttaggttgaa tgatagagtt tttgttttta aaataaaata aaataaaata 201780 aaataaaata ataaagttag tttgtgtatt ggattgtatg ttgttttaaa gtatttaaag 201840 tgagagaggt taggaagtaa tgagatgtag aaaggtaggg ggaggaggtt tagaggtatt 201900 agagaagata gttgattttt atttttatat atttttgggg tattttgagt tttatttata 201960 tatttaggtg agaatttttg tatttgtgaa agtaatttga ggttgagaga attaatagga 202020 aattgtttta ttttttatgt agggtttttt tataaataag gttgagttgt agtttattat 202080 tgtagttgag ttttttgtag tagttgtggt ggggaaggtt ttttaggagg tttgagtaat 202140 ttagaaatat ttatagtata ttttttagtt tttttagagg tttttgttga gatgaaagtg 202200 ttttggtttg tggttaaaga gtttagtata ttgggtagtt atagttttta ttatattgat 202260 ttggttatta ggtttttatg aatttagtga ggggagatgg gttttttagg gaagtttgtt 202320 gattttttta tattgttgta aatgtaaagt ttggtgattt tattattttt agtaattgtg 202380 atgtagtaat aataagaata gttatgttta ttgtttattg aaggtatatg atgagttaga 202440 tattgtgttg gtatatgtga tttttggagg taatatattt ttttttaagg aggaaatgat 202500 tgagttttgg agggagggtt ttttatttgg ttttaggttt ttttttgatt tgtgtttttt 202560 tttttttttt tgtttgtttt attgtagttt ttttggtttt tttgttgttt ttggaatgta 202620 ttaagtttgt ttttagttta gtttttgtat tgttggtttt tttttgtttt tttaatttta 202680 atttagttgt tattattttt gtgatttttt attatttatt ttaaagtagt tattagttat 202740 tttttatgta attattttat tttaattttt attatagttt ttagttttat tttgatagtt 202800 tttagaattg atgaatttat tgattttgtt tttttttatt gtatgtaaat tttaagaaat 202860 aagagttttt gtttgtttat tgttgtgttt tagtgtttgt tatagtattt ggtatgtagt 202920 aggtgtttaa tgaatatatt tttaaaagaa tgaatgattg gaaggagttt gaaagaatga 202980 tggtttgtgt taatagttta tttttaattt ttttagatgg gatggagatt attattatgt 203040 aattatgatt tttttgagtt tgtgtggtgg ttgatggtag gtgttagttt ggttggatta 203100 agggatggtt ggtaatgtat tgtttttggg tgtgtttgtg agggtgtttt tggaggagat 203160 gggtatgtga gttggtgggt tgagtggtaa agattttttt ttaatatgga tgatattatt 203220 ttattgttag ataataaaaa ggtagagaaa aggtgaattt tttttttttt ttggaggtgg 203280 gatgtttttt ttttttgttt ttggatttag aatttttagt tttttagtag ttttttaggt 203340 ttttaaattt ttggttttaa attaagagtt atattaatag ttttttagtt ttgaggtttg 203400 tagatttgga ttgagttatg atattggttt ttttgggttt ttagtttgtg gatggttttt 203460 tgtggtatat tttggttttt ataatggtat gagttaattt ttttaataaa ttttttttta 203520 tttatttatt atttattttt ttaattgttt atttgtttat ttatttattt atttattatt 203580 tattttttat ttatttattt attatttatt taattaatgt atttatgttt gtttgtttat 203640 tggttattta tatttattta ttaattattt atttatttat tatttatttg ttatttattt 203700 agttatttat ttatttattt atttattttt tttttttttt tgagatggag ttttattttg 203760 ttgtttaggt tggagtgtag tggtgtgatt ttagtttatt gtaattttta ttttttaggt 203820 ttaagtgatt tttgtgtttt agttttttga gtggttggga ttatagatat gtattattat 203880 gtttagttaa tttttttatt tttagtagag atggggtttt attttgttag ttaggttggt 203940 tttaaatttt tggttttaag tgatttattg gttttagttt attaatgtgt tggttattat 204000 aggtaagagt tattgaattt aatttattat ttgtttgttt gtttgtttgt ttgtttgtgt 204060 ttatttgttt gtttggttat ttattattta tttatttatt tgtttgtttg tttgtttgtt 204120 tgtttgtgtt tgtttgtttt tatttttttg tttgtttgtt tatttagtta tttgtttgtt 204180 tgtttgtttg tgtttgtttg tttttttttt tttttgtttg tttgtttgtt tatttagtta 204240 tttatttatt tatttatttt ttattggttg tttttttgga gagttttggt tgatgtagat 204300 ggtgttttgg taagtttagg ttgttattta gattattgtg gagggagtga tttaaataat 204360 agatatgtat tttttagttt gagaggttta aagttttgga ttaaggtgtt gttagggtta 204420 gtttttggtg aggttttttt ttttggtttg tatttatttt tttgttgtgt tttttgttat 204480 tttttttttg tttataagtg aggggggagg agagattttt ggtgtttttt ttttttttta 204540 taaggatatt aattttatta gattagggtt ttgttttatg attttattta attttaatta 204600 tttttttaaa agttttattt ttaattatag ttgtattggg agttagggtt ttaatgtagg 204660 aatttaaggg gaagggtata gtttggttta taataaatgg gaaattatgt ttatgattaa 204720 attttttaga agatatggtt tattagtgtt gttaatgatt gtaagtaaag gttagagagg 204780 aaaggggttt ttgtggggtg gggggtggtg ggggtagttg gtgttgggaa taaggttttt 204840 ttttttgttt aatagtaggg aagtgaggtt ggttgtagat gttatttggg gtgggaagag 204900 aggggagttt ttgtttgtat attttgtgtg ggttttggtt tgattttttt ttgtgttttt 204960 tattttttgt gttttttttt gtgtgggaga aatgttgatt tttgttggtt taggtgttta 205020 ggtttttagg tttgttggtt ttgggttggg tttaattaat gagaggtttg ggaggaattt 205080 gggaggtgga agtaagggag ggtgtgggag ttttttattt tttttgtttt agatagtttt 205140 tttagtagga gaggtggttt tttgtgtagt tttagttttt gttagagttt tatttttgtt 205200 tgggttttta gtaggtgatt ttggtttttg gattttggtt ataggatttt ttttttttta 205260 tttttattta ggggtggtgg tggtattttg ttgttaattt ttaggttatt tttataatgt 205320 taagaatttt ttttttattt gtatggtttt tttttaaggt attgagaagg gttttaatta 205380 tatgtttata gggttaaata ttttttgtaa aatttataaa atggaaaata ttttttttat 205440 aattaattaa tgtttttgtt tatttttagt tttgagtttt tgtttgttat attttttttt 205500 gtgtgaggtg gaaatggagg tttgttgtta tgtgggggtt tttgttaagg agaagttgaa 205560 ttggaaagat atttagtttg gttttggttg ggttatattt atgtagtttt tatttatttt 205620 tatgtatagt ttagttattg tttgttattt tggtgtggaa atggatttta gtaatatttg 205680 ttttatttat tgttttaatt ttatttattg tgtagaatta aaaattataa gatatgaata 205740 tattttgtgg tgtttggtgt tggaaaaatg tgtgtagtgg agagaagtaa gatttgaaat 205800 gtatgggttt agaagtaaat ttgtggaaaa ttatttttat tattagaggt gaagttgtaa 205860 gtaaaggatt tagttttttt aatgtggagt taaaatagaa aagttttttt ggttagaaat 205920 atatgtataa atgttttata tgtagttaga aatttttttt atttttttat tttttttttg 205980 atgggaatta tatttaaaaa aaaagaaaaa aataggattt attagaattt ttgtgtattt 206040 tgaataaaat aattgtagta gtattattaa ttttatgttg attgttattt ttgtatatat 206100 tttaattatt aaaaataaaa ataaaatttg attaattaag gagatttatt tgttttattt 206160 atttatttat ttttgagatg gagttttatt ttgttgttta ggttggagtg taatggtatg 206220 attttggttt attgtaattt ttgttttttg ggtttaagtt atttttttgt tttagttttt 206280 taagtagttg ggattatagg tgtgtgttat tatatttggt taatttttta tgtttttggt 206340 agagatgggg ttttattatg ttgattaggt tggttttaaa tttttgattt taagtgattt 206400 gtttatttta attttttata gtgttggaat tataggtgtg agttattatg tttagtttat 206460 gttttttttt gttgtttttt tttttttttt gagatatggt tttatttttt tatttaggtt 206520 ggagtgtagt ggtatgatta tggtttattg tagttttgat tttttgggtt taagtaattt 206580 ttttatttta gttttttaag taattgggat tataggtgta tgttattatg ttttgttagt 206640 ttttgtattt ttagtagaga tggggttttg ttatgttgtt tggattggtt ttgaattttt 206700 ggttttaagt gatttatttg ttttggtttt ttaaagtgtt gggattatag gtatgagtta 206760 ttgtgtttag tttgattagt tttttgtttt tgaaatagaa aatgatatta taaagttatt 206820 atattgaaga agtaatgtta aaaatgtggg agaaatagaa ttttggagat atgattgata 206880 gttgattggt atttttttgt atgtagtgat gtttgtgata tttaatagtt gtttataatt 206940 tataatttgt tgttatttat ttttttattt taaatgaatt attgtattta tatttttaga 207000 gggttgtata agtttatatt attttgattt tttgttgatt gtttttttgt tttttgtttg 207060 gtttttattt tttttattat ttgtgtaatt agttttttgt ttttaagttt ttttgtttta 207120 aatgtttaag tggattaggt attgtggttt ttgtttgtaa ttttagtatt ttgggaggtt 207180 taggtaggag gattatataa atttaggagt ataagattaa tttgggtaat atagtaagat 207240 tttgttttta tatatatata aaaaatataa aaattagtaa ggtgtgatgg tatatgtttg 207300 tagttttagt attttgggag gttgaggtag gaggattgtt tgaggttggg agtttaggat 207360 tagtttgggt aataaagtaa gattttgttt ttataaaaat aaaagaaaaa attaggtagg 207420 tatatagtgt gtatttatag tttgagttat ttgggaggtt gagaagggag gattgtttga 207480 gtttaggagt ttaaggttgt tatgagttgt gattatatta ttgtatttta gtttgtgtga 207540 tagagtgaga ttttgttttg ggaaaaataa ataaataaat aaataaataa ataaataaat 207600 aaatgtttaa gtggttttta ttttttggtt agattttatt atatatttta tgaataaatt 207660 gtatgtatga gaaaggtgag tagatgaata gggtagggtt agggggttaa ggggaagatt 207720 atagattatg tggagtgaga ttagtggtta aaaattgtta attatagtta ggtttggtgg 207780 tttatgaagg taattttaat ggttgggttt ggtggtttat gtttgtaatt ttagtatttt 207840 gggaggttga tgtgagttta ttatttgagg ttaagagttt gagattagtt tggttaatgt 207900 agggaaattt tgtttttatt aaaaatatta aaattggtta ggtatggtgg tgggtgtttg 207960 tagttttagt tatttgggag gttgaagtag gagaattggt tgaatttggg aggtggaggt 208020 tgtagtgagt tgggatttta ttattgtatt ttagtttggg tgatagagtg agattttatt 208080 ttaaaaaatt taaaaaaaaa aaaataaaaa attgtagatt ttaataagga agagttatag 208140 gatgatattt taggatgtgg gaaaaggtta tgttagtttt ggattttttt tgattaatgg 208200 gtattttagt tattaaaggg gtagatgtgt tttatttaat ttttatttag ttattagagt 208260 ataatatagg gatgtgttat agatagagat ggagattaat aggtagaggg gtgatgggga 208320 ggaagattga ggtaagagga ataaaatggg gattgtagag ggtaggtggt aggagtttga 208380 gggttttaga agaaattgtt gtataagtaa tgagttagta gggtgagtga tggttaggag 208440 aggtggttta agaaaataaa gagatatttt tgggggtata gatgtgtttt gaggggttga 208500 ggaagagatg gggaaggggt ggttttgtgg atttttggta tgattgttgt ggtgaaaagg 208560 aattaaagat tttgataagg ggatgatttt ttaaataagg aagttttggg tttttgtagg 208620 gggattagta gattgagggt aaatggtatt ttgtttatta aagttttaat aaaatgttaa 208680 ggtaagaata tttgtttggt tttgggggta attttagaaa tattagaaaa gggatttatt 208740 atgtgtaatt tttttttaat tatttggaga aatgtatggt tatttaagat agagaaaggt 208800 agttaaagta agtggaggtt aggtatagtg atttatgttt gtatttttag tgttttggga 208860 ggttgaggta ggaggattgt ttgaggttgg aaatttagta ttagtttagg taataataaa 208920 ataagatttt gttgttataa aaataaaaat aaaaattttt tgagatggag ttttattttt 208980 tttgtttagg ttggagtgtt gtggtatgat tttagtttat tgtaattttt gttttttaga 209040 tttaagtaat ttttttgttt tagttttttg agtagttggg attataggta tgtgttatta 209100 tgtttagtta attttgtagt tttagtagag atagggtttt tttatgttgg ttaggttggt 209160 tttgaatttt tgattttttt ggttttttaa agtgttagga ttataggtat gagttattgt 209220 gtttggttgt tataaaaatt ttttaaaaat tagttaggta tgttaggtgt ggtggttttt 209280 atttgtaatt ttagtatttt gggaggttaa ggtaggtgga ttatgaggtt aggagtttga 209340 gattagtttg attaatatgg tgaaattttg tttttattaa aaatataaaa attagttagg 209400 tgtggtggta tatgtttgta attgtagtta tttaggaggt tgaggtagga gaattgtttt 209460 aatttaggag ttgggggttg tagtgagttg agattgtatt atggtatttt agtttgggta 209520 atagagtaag attttgtttt aaaaaaaaaa aaaaaaaaaa aattagttag gtatgtagtg 209580 tatatttgta gttttagtta tttaggaggt tgagaaggga ggattaattg aaattgggag 209640 gttgagattg ggaggttatg attatgttat tgtattttaa tttgggtaat atagtaagat 209700 tttgtttaat aataataata ataaataatg taagtgggta taagaattta tttatttatt 209760 tatttattta tttatttatg agatagggtt ttattttgtt gtttaggttg gagtgtattg 209820 gtgtaatttt ggtttattgt aagttttgtt ttttgggttt atgttatttt tttgttttag 209880 ttttttgagt agttgggatt ataggtgttt gttattgtat ttagttaatt ttttgtattt 209940 ttagtagaga tggggtttta ttatggtttt gattttttga ttttgtgatt tgtttgtttt 210000 ggttttttaa agtgttggga ttataggtgt gagttattgt ttttggtttt aagaatttat 210060 tttattttag tattttggag gttgaggtga gtggattatg aggttagaag attgagatta 210120 ttttggttaa tatggtgaaa ttttgttttt attaaaaaaa tataaaaaat tagttgggtg 210180 tgggggtggg tgtttgtagt tttagttatg tgggatgttg aggtaggaga atggtgtgaa 210240 tttgggaggt ggagtttgta gtgagtggag attgtgttat tgtattttag tttgggtaat 210300 agagtgagat tttattttaa aaaaaaaaaa aaaagaattt attttaagat agtaagtttt 210360 agggttgaag ttagttttta tttagtttta ggtttaaagt tataagtatg gttattgtaa 210420 tatttttatt taggatatta ttttttaggg gtttagattt atattattaa ggaggagtgt 210480 ttatattagt agttggggag agggtggttt tttataagat gtaatgttta ttttgaagag 210540 ttattatagt gataattatg aaatttatgt ttgagattta attttaagtg aaaagaatag 210600 aatttaatat ttattttatg gggagtataa aattttgaaa atatatgttt tttataatta 210660 aattaaattt tatgttatgt ttttgaggag ataagtattg aatggaatat agaagaaatg 210720 ttatagttaa tgattgttga agtttttttt ttaatttttt gtttatgttg tttggtaata 210780 agtaatatag aaaattgata ataaaaagta aaagagaaag aaaagatata gtgtatagtt 210840 tagattgttt tttttaaaaa attaaataat aataataaaa agtataggtt gggtgtggtg 210900 gtttatgttt gtaattttag tattttggga ggttaaggtg ggtggattat ttgaggttgg 210960 gagtttgaga ttagtttgat taatatgggg atattttgtt tgtattaaaa atataaaatt 211020 agttgggtat ggtgatgtag gtttgtaatt ttagttattt gggaggttga ggtaagagaa 211080 ttgtttgaat ttgggaggtg gaggttgtag tgagttgaga ttgtgttttt gtattttagt 211140 ttgggtaata agagtgaaat tttattttaa aaaaaaaaaa aaaaaagtat aaatgtaagt 211200 tgggtgtggt agtttatgtt tgtaatttta gtattttggg aggttggggt aggtggatta 211260 tttgaggtta ggagtttgaa attaatttgg ttaatatggt gaaattttat ttttattaaa 211320 aatataaaaa ttagttaggt atggtggtgt gtgtttgtaa ttttagttat ttaggaggtt 211380 gaggtaggag aattgtttga atttaggagg tagaggttgt agtgagttaa gattgagtta 211440 ttatatttta gtttgggtga tagagtgaga ttttgtttta aaaattaaat taaattaaat 211500 taaataaaat aaaaaaaaga agtggtataa tataaagttt tggtagttaa agtgttaatt 211560 tttagttatt aggaaggttt tgttatttaa tgatttattg ttttagttaa ggttagttat 211620 attttgggtt tttgatgttg gaggtaatat gatgttaata ttggtgagaa atttattatt 211680 tttttttttt tgttttttgg tgttggtttt tgtgtgtatt tgtagttttt ttattattgg 211740 tgtttttatg gtgtttatgt tattggttta ttttttagta ataatttgat agtttgatat 211800 ttttgtagat tttgtggtta tagagttaaa gttttttgtt attagtgggt tttgtagata 211860 attttttaaa tttttttggg ttgagttagt taagttttta ataagttgga agatgatagg 211920 ggttggatgt aatttatttt taattggttt gggttatatg gatattattt tttttttggg 211980 atttgatttg ggatggaaat aggagttata gtttatggga aggttgtgaa aggaagtttt 212040 ggttttaggg tgtggattag gttgatttgt ggaataaggt tttaggggtg gtttatttgt 212100 ttgttttgtt tagttttttt tggtaattat atttatttgg ggtttatttt aaatttggta 212160 ggtaatgttg ttgtttttat tttagttgtt gttttaatat gttttgtttg gttaggatag 212220 gtgtttaggt atggtattta gggatatttt tggtttttgg ggtttaattt ttggttttta 212280 ggtgtagtgt tgggaaaagt agagggtttt ggttatggtg taggttttgt tataggttat 212340 ttaagtagtt tgggaggagt tggaaagaga gtaatgtatt tatttggata gagattgaag 212400 ttatattttt attgagaaaa gatgatattt ttgtttggat tttttttttg aaattttagg 212460 ttggggtggg gtaggagtta gtgagagagt ttagtgtttt aaaggggatt ttttggtttt 212520 ttgtgttttt taatttagta tttttgggga tttatatatt tagggtagag tggttattta 212580 gggttttttt tatttagata taaaggttat tgaaggtttt gggttaatat tgttttgagg 212640 atgattagtg atttgagttt ttgttagaga tagtaggtag tttgggttta agggttgttt 212700 agtgatttga agttgggatt attttatatt ttttgtgtta tttttgtttt ttgttttgga 212760 ggtttttagg ttgttaatag ttatgttttg gagaattagg ttagattagg ttgggaataa 212820 agtttagttg ttatagagtt gttgagaggt tattggtaag tagtgtttag gagttgtttt 212880 ttttttgtta gtaatagttt aatgtttttt tttatagggg ttgtaaatgg gtttatgttt 212940 agggtggggt tagggagata aagtagagag aaattgggtt gggagtagag agtgttatgt 213000 tttattttgg agatttaagg ttaggttatt ttgtagagtt ggtgtttaga gtttttagtg 213060 tataggagag gaggtaaata gaatttgata tttagtagtg tttggtagat gtttttggaa 213120 tgaatgatta aatttatatg gagagttgaa atgggttagg aattttaggg agatgggtag 213180 tttatagttt agtagggttg ttttagtaga gtaggttaat gttaggtttt ttggtaaatt 213240 ttttggggtt taggtataat tgttatatta ggaaaggggt aggggtgatt agtttattgg 213300 ttatgggggt attttattgt ttttatagaa gtttggtatt tataggtttg ggtgatatat 213360 gatttttatg tttggtatta tgatggttgt ttattaagtt tttttattta ttaggattga 213420 ttttttttgg ttagtgattt tagattatta tgatttggta gttgttgtta ggtttgtttg 213480 gttaaggatt tttttggaga ttgagttatt ttatatagta aagtgagtta tggggttata 213540 gtgttgtgtg ttgtgtataa gttttgaggg ttttatttag ggattggtat ttattgattt 213600 ttataaattt ttggtaattg tttagagttg ggatgttttt aaggtaatag ttttaataaa 213660 tagaggtgta ggaatttagt gtgttatttt ttgttttatt ttaaaggttt atatttttag 213720 gggtttggag tttttttttg gagttttttt tattttaaag ttagttggat ttgtttagga 213780 attgttatta ttattttttg gttgggtttg tattgatgtg tattgaattt tttttattag 213840 gtttatttta ggtaaatttt agagtttatg taatattgtt tgtggataaa tattggggtg 213900 gaaatagggg ttatttttag gttttagtta tatggggttg ttagggttgt ttgggatggt 213960 aggagagtgt tagaggaggg tagtttaagg attaggtagg gggtgggaag tgtttttttt 214020 tatgggtttt taagtgagat gttttttgta aatatttatt tgggattttt aagtagaggg 214080 ttggttttta tgttatttgg atttggattt tagattattg tttttaagtg gtaattttgg 214140 gtttttttgt atttgttttg gtttgagttg gttatatttg tggggggtgg ttttaggaag 214200 aaggtggatt gttgtaaatg taatgttttg ttgttaggtg tattgttttt ggttattaga 214260 atttttttgg gtaggttggg gagatttgat gggtaagtgt ttgtggtttg gtgtgagtgg 214320 gtagggtagg tggtttttgt ttgggtatgt ttttttattt ttgtaataga ttagggagag 214380 ggttggtttt aggatttagg tttagttagt tgttttataa ttgaggggtt ttggtggagg 214440 atataagtta gatagagtta tagattaatt gtatgaggtg gttttttttt tttagtttag 214500 gttttttgaa tgtgttagag tagataagtt tggatgtgag gaggtaagag gtagtgagaa 214560 taggtgtgga gatggggttg ggggagaaga ggaagaaatt ttgtgtttgt gtttttttta 214620 tgtttgtttg ttattgggtt agttgattgg ggaagtgttt tttgagggtg taattttttg 214680 ttttttttgt aagttagttt ttggggtgtt gggtgagggt gtagttttgt ttattatggt 214740 gagttagtat attgaattat ggtagaagtt gttttttgtg tgggtgtagt tttttttttt 214800 gtttaggatt tagaagttat gatagtatag agttttttaa ttgtggttgg tgttttttta 214860 ggaatttttt gaaagttata gagaaatttt agagtggttg ggtatggtgg tttatgtttg 214920 tgattttagt attttgggag gttgaggtgg gtggattatt tgaggtttgg agtttgagat 214980 tagtttggtt agtatggtaa aattttattt ttattaaaaa atataaaaat tagttgggta 215040 tggtggtata tgtttgtaat tttagttatt taggaggttg aggtatgaga attgtttgaa 215100 tttgggaggt agaggttgta gtgaattgag attgtgttat tgtattttag tttgggtaat 215160 agagtaagat tttattttaa aaaaataaaa aataaaaaaa gaatttttag agtaattttt 215220 aggtgttagt aggggtgtga tgtaatttta gttttgtttt tgtggtttat tggttttggg 215280 taagtttttt tgttgttgtt atttatagag agtttttagg ggagtttggg aatgatggta 215340 agttttatgt gatttagtat gtaaagggag ttttaaaatt tagaatttag agagttaggg 215400 tgggtatagt gtagttggtt ttagtgttga ggggttgggg gagagatttt gtattatgtt 215460 ttgattatag taagggaaga ttatggaggt ttttggaatg ttttagtaat ggtgtaattt 215520 tagttttttt tatttttttg ttaatgataa ttatgattat gatagtagtt aataggttat 215580 agagtaggta ttttttagtt tttttaaata tgaatttgtt taatttttat aataatatag 215640 tattgtttta tttaataaat gaggtaggtt gggtgtggtg gtttatgttt gtaattatag 215700 tattttggga ggttaaggta ggtagattat gaggttagga gtttgagatt agtttgatta 215760 atatggtgaa attttatttt tagtaaaaat ataaaaatta gttgggtgta gtggtatgtt 215820 tttataattt tagttattta ggaggttgag gtaggagaat tatttgaatt tgggaggtgg 215880 aggttgtagt aagttgagat tatgttattg tattttagtt tgggagatag agtgagattt 215940 tgttttaaaa ataaataaat aaataaaatt aaaaaatatt atatatataa aaaaataaat 216000 gaggtaaatg agatgtatga ggtgagaatt ttgtgttata gggagaggtg tagtttggtg 216060 agatttaatt ttaaggggtt ggtggttttg agtttttaag tgtaattatt ggattatatt 216120 gtttgtagat tattattatt tttattttat tggaaggttg ggtgaggtaa ttgggaaagt 216180 ttggagtagt agtggagttg ttagagagaa tttgttttta gtgttttttt ggattttgta 216240 gttgttttgt gtgggttttt gttgtttttt gtattggaaa agattttttt atagatgggg 216300 ttttatgatg ttatttaggt tggagtgttg tgtttatttt taggtgttgt tatagggttg 216360 tagttttgaa tttttggttt taagtgattt ttttgtttta gttttttgag tagttttttg 216420 ggtttaagtg atttttgtgt tttagttttt tgagtagttt tttgggttta agtgattttt 216480 gtgttttagt tttttgagta gttgggattt taagtgtatt tggttaagtt tttttttatt 216540 ttttattatt taagattttt ttttttttaa ggtttagttt aattttattt ttatttaaaa 216600 tttttggggt atttttgtag tatttggagg ttgaattgtt taggagggaa gggtgttaat 216660 gagttggtgt tttgttttta ttttgatttt tggtgagaat gtaagttttt tgtaggtaag 216720 gattatattt tattattatt tttgtattta tttagatttg gttatgtgtg tttagtatat 216780 aaagtgtttt tgatgattgt ttatagattt atggtatttg agattgtttt aatatatttt 216840 tttaaaattt tttttttttt tagaggttta tgaatgttta aattaggttt attgggaata 216900 atattatggt tattttgttt attttgaagt ttatatatag gtttggaagt aataattttg 216960 tatagtttag atgaaaaaat aaagattttt ttgttgtttt tggattgtta gagttttggg 217020 ggatttttaa tattttttgt tgtttttttt aattttatgg tgttgatggt ttgttggggg 217080 gttagtttga tttttgtgag tgtttgtatt tggaaaaggg ttggtgttaa gatagtttta 217140 ggatatttag aatgagggta agaggttatt tttattatta gtttttttta gttttatttt 217200 atataattgt aatatagtga tttagtatat tttgggttat tgttaagtag ggagtaaatt 217260 agaaatggtt tgagtttttt ttttttttat ttttagaggg gtttgttttt ttaggtaaat 217320 ataaggaggt attgaggttg ttgtataaga gttggttttt gtttatttta taaattttat 217380 ttttatttat tgtaaaaggt tttgtttttt tttttaaaaa aaaaaaaaaa aaagaaattt 217440 agtgaggggt ggggtaggtg tgtgtggagg agaggagaaa aggataagtg atggtttttt 217500 tattttttag taagttgtag gtgtagagat tttaagtttg ttttagggtt tttttggtat 217560 ttgtgtagga gggtttttgt agaaaaaatt taggatttat gatttgggag gattttggtt 217620 atttttattg tttggattta ttagtgggag gtaaagtgta agaaattaag ggtaaagggt 217680 tttttttggg tgggttagag attttttgga aagggttatg tattgtgtga tttttataat 217740 aattttaagt atttggagta tgttggggag gaagttttgg tgttaaaatt aagtatgtgt 217800 tatttggaag tttgtttttg tttattagta tattaattta tttatgtttt tgatagagtt 217860 gtgttttggg tgtgtagagg gttattttgt ttgtaataat tgggtgaaag ttgaaatttt 217920 aagttattga tttagaaggg tatttttggg gaagttttga gtaatttttt ttgagataag 217980 gtattttatt atttattttg gtttttaaat atggaaagtt agaggaaatt gataatggtt 218040 taaaggtagg gggatggttt tgatgatttt tttattttta attaaggttt atgattttgt 218100 ttttttatta ataaaaatta atttatggat ttttggtagg tattttttta tttgaatgaa 218160 ttaaaggagg gatattaaat aaatggtttt tagatttaga agaggagatg ttatttataa 218220 tttgaggatt gaggaggata aaggattttg tttgtttgga ttttttggag aaaattataa 218280 aggaaaaaaa aaaggaagga aaagataaat aatgaagatt tggatttttt ttaatttgtt 218340 tttgtggttt tggtgtgttt atttgtgaaa tggaatttta gagtgttaga gtgggagttt 218400 tttatgaaat gaaagttttt gaattggttt atggtgaggt ttaagttagg ttttttttgt 218460 ttatttaagg tgggttttgt tagggtggag tgaggatgtt agttgtgggt ggtgttttga 218520 gtgtaaaatg tgaatttgag ttgttaagtt tgggtgttgt tggatggttt tatttggagg 218580 ttgttttgtg ttttattaag tagaggagaa attgaagaga atttgaagaa aggatgttgt 218640 ggtttggatt attagtttta gaggttgaat ttaaggatat ttttttattt agttttgatt 218700 ttatttattt atatagatgt atagggattt aaagtatttg gttgatttgg aaagttagtg 218760 atttttgtga gggtgtaagg ggtgaggaag agggagtgtt ttttagggta gtttttttga 218820 tatttgagta agggttggag atagtgtagg ggatggttgg tttaggttga aagtggtttg 218880 atagtggttt tgttttggga ggaatttgat ttgtagtgtg tttgttgtgg ggatttgttt 218940 agttttgggg gtgttttgtt atttttggtt gtaggtattt aggtgagtag tgttggtttt 219000 gggatattga ttttttttta ttttgggtgt gaagtttatt tgagtaagat ttttttatgg 219060 tgtttttgtg gttgttgttt ttaggaaagt gtggtggtga ggtagtgggg tgtgtgtttt 219120 tagggtgtta attttgggtt ggtagtagga aggtgggaag agggggtggt ttgttgtttg 219180 gagtgtattg attgggtttt gttttggttt tgtttttgtt ttgttttttt ttggagatgt 219240 gtatagaatt ttggtttagt tggttgtggt tttgtttttg atttgttttt tttttgtttt 219300 gtgaatgtgt gtgttgagtt ttatttttgt ttatttttgt gttgtgttgt atttggtgga 219360 gtggggttgg tgggtgttgg gtttgggagg gggtgttttt gtgtggtagt gtagattaga 219420 ttagattagg ttaggttggg ggtgggggtt gtttgtgtgg tttgttgtgt ttgtagtttt 219480 gtatttttag ttttttgtgt tggtgttaat ggttggtttt gggagttgtt gtatttttta 219540 gttttgagtt tgggtggggt gggtttggtt aggtggaagt gggtggaggt gtgggtgttt 219600 tgggtggttt tgttgggtga ggtggtggtg ttgggtattg tggtggtgtt gggtatagtt 219660 gggggttgga gttggggtgt tggtttagtg ggttggggta gggtgggata ggatatttgt 219720 tttgttattt ttttggtaat taaaagggta gagtgtgttg attgagttgg agttttagtt 219780 tttttatttg taaatgggtg tgttggatag atgattattt gttttttttg tgttgggtat 219840 tgtgtgtagt ttggtgtatt ggtgtagtgg ggtagatata gggagttgtt ttttataatt 219900 tgggtaatg 219909 <210> 12 <211> 1405 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 12 tgttatttga gttgtaaagg gtggtttttt gtgtttgttt tgttgtattg atatattgag 60 ttgtgtatgg tgtttagtgt agggagaata aatgattatt tgtttaatgt gtttatttat 120 aggtgaggaa attaaggttt taatttaatt gatgtatttt gtttttttga ttattagaaa 180 agtagtagga taggtgtttt gttttgtttt attttggttt attaagttgg tattttggtt 240 ttgatttttg gttgtgtttg gtgttgttgt ggtgtttggt gttgttgttt tgtttggtgg 300 ggttgtttgg agtgtttgta tttttgtttg tttttatttg gttgggtttg ttttgtttgg 360 atttgggatt gggaagtgtg gtgatttttg gaattagtta ttggtgttag tgtggggagt 420 tgggggtgta gagttgtggg tgtggtgggt tatgtaggtg gtttttattt ttggtttggt 480 ttggtttggt ttggtttgtg ttgttgtgtg ggggtgtttt tttttaggtt tggtgtttgt 540 tagttttgtt ttgttaggtg tagtgtagtg taggggtggg tgggggtggg gtttggtgtg 600 tatgtttatg gggtggggag ggggtgggtt aggggtggga ttatagttgg ttgggttggg 660 gttttatgtg tatttttggg gaggggtggg gtgggggtgg ggttggggtg gggtttggtt 720 ggtgtatttt agatggtggg ttgttttttt tttttgtttt tttattattg gtttaggatt 780 agtgttttgg gagtgtgtgt tttgttgttt tgttgttata tttttttggg agtggtggtt 840 atggaggtat tatgaagaag ttttatttag gtgggttttg tgtttggggt ggggaggggt 900 tggtgttttg ggattagtgt tgtttatttg agtgtttgtg gttgggagtg gtgaggtgtt 960 tttggagttg agtgagtttt tgtggtgggt atattgtagg ttgagttttt tttaggatag 1020 ggttgttgtt gggttgtttt tgatttgagt tgattgtttt ttgtgttgtt tttagttttt 1080 gtttgagtgt tggaggggtt gttttggggg atgttttttt ttttttgttt tttgtatttt 1140 tgtaggaatt gttgattttt taggttggtt gggtgttttg ggtttttgtg tgtttgtgtg 1200 ggtgaatggg gttggggtta ggtggagggg tgtttttggg tttagttttt agggttggtg 1260 gtttaggttg tagtattttt tttttggatt ttttttggtt ttttttttat ttagtggggt 1320 atgggatggt ttttagatgg gattgtttag tagtgtttaa atttggtgat ttgggtttat 1380 gttttgtgtt taggatgttg tttgt 1405 <210> 13 <211> 1405 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 13 gtgggtggtg ttttgagtgt aaaatgtgaa tttgagttgt taagtttggg tgttgttgga 60 tggttttatt tggaggttgt tttgtgtttt attaagtaga ggagaaattg aagagaattt 120 gaagaaagga tgttgtggtt tggattatta gttttagagg ttgaatttaa ggatattttt 180 ttatttagtt ttgattttat ttatttatat agatgtatag ggatttaaag tatttggttg 240 atttggaaag ttagtgattt ttgtgagggt gtaaggggtg aggaagaggg agtgtttttt 300 agggtagttt ttttgatatt tgagtaaggg ttggagatag tgtaggggat ggttggttta 360 ggttgaaagt ggtttgatag tggttttgtt ttgggaggaa tttgatttgt agtgtgtttg 420 ttgtggggat ttgtttagtt ttgggggtgt tttgttattt ttggttgtag gtatttaggt 480 gagtagtgtt ggttttggga tattgatttt tttttatttt gggtgtgaag tttatttgag 540 taagattttt ttatggtgtt tttgtggttg ttgtttttag gaaagtgtgg tggtgaggta 600 gtggggtgtg tgtttttagg gtgttaattt tgggttggta gtaggaaggt gggaagaggg 660 ggtggtttgt tgtttggagt gtattgattg ggttttgttt tggttttgtt tttgttttgt 720 ttttttttgg agatgtgtat agaattttgg tttagttggt tgtggttttg tttttgattt 780 gttttttttt tgttttgtga atgtgtgtgt tgagttttat ttttgtttat ttttgtgttg 840 tgttgtattt ggtggagtgg ggttggtggg tgttgggttt gggagggggt gtttttgtgt 900 ggtagtgtag attagattag attaggttag gttgggggtg ggggttgttt gtgtggtttg 960 ttgtgtttgt agttttgtat ttttagtttt ttgtgttggt gttaatggtt ggttttggga 1020 gttgttgtat tttttagttt tgagtttggg tggggtgggt ttggttaggt ggaagtgggt 1080 ggaggtgtgg gtgttttggg tggttttgtt gggtgaggtg gtggtgttgg gtattgtggt 1140 ggtgttgggt atagttgggg gttggagttg gggtgttggt ttagtgggtt ggggtagggt 1200 gggataggat atttgttttg ttattttttt ggtaattaaa agggtagagt gtgttgattg 1260 agttggagtt ttagtttttt tatttgtaaa tgggtgtgtt ggatagatga ttatttgttt 1320 tttttgtgtt gggtattgtg tgtagtttgg tgtattggtg tagtggggta gatataggga 1380 gttgtttttt ataatttggg taatg 1405 <210> 14 <211> 2365 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 14 gtggttgtgg tgggggtgtt agttgtaggg gtgtttttgg tgggtgggag ttggtggttt 60 tttgttggtg ttatgggatt tgtatgtttg ttttgtgttt tttggttttt gagtttatag 120 gttgggattt tgtttgttag ttgtgtgtgt tgttgtttaa tttttgtagg tgtagagtgt 180 gtggtggtgg tgatagagaa ttttgtttgg ttgtttaaat atagtttttt gtagaaggat 240 tttgtgtttg gggaagggga ggaatttttt tttttttggg tgtttgtttt ttttgttatg 300 gtttggtttt tatatttgtt tatatttggt tgtagtgggg tgtttggggg gaggggttga 360 ggttgtgttt tttgttgttt tttgggtgtg ggttaggtgg ggaggagggg ggtgttttgg 420 ttgtgtgttt aggattgttt tttagtggtt atttgggttt tagtttttta ggtttggttt 480 tgataggtgg gtggagtagt tagtgtgaga tagggaggtt ggtgtgggtg tgggaatttg 540 atttgtttgg gaggtggggg tggggtgggg gtgtagtgtg tggggagggg ttggtgtttg 600 tttttttttt ttatttattt agttgagtta gggggtttag gggttttttt ggtggttagt 660 tttgtattgt aggagtgtgg gtgtggtgtt ttagttagtg tgtagggttt gggttttgtt 720 gggggtgttt ttttgttgtt gttttttgtg tgatttgttg tttattagtt attatgttgg 780 attttgtggt taatgtgtag ttggatggga ttattttgga ttttgaaggt gggtgttggg 840 ttggttgttg tggttgtgga tgtgttggag aggattttgt gggtgggttt ggtgtgggat 900 gggggtgtgt tgaggggaga tgggagtgtg ttgaggggag atgggatttt taatttaggt 960 gtttttttgt tgagagtgtt gtgtgttttt ggttttgtgt ttgtgttgtt tatgtggggg 1020 attttgttag gggtatttgt gtagattttg tgtgttttta taggattttg tgtttgtttt 1080 gtgtattgtt gtttgggttt tttttttttt attgttgttt gtgtttgtta agtgatagtg 1140 atttttttga gggtttgtga ggttgttttg gaatttttta ggatgtatag ttttattttg 1200 ggaaatttat tggttttttt tttttggttt tttttggtgg tttttgggtt ttgtttggat 1260 ttggtaatgg gatagggagg ttgtttttta tttttgattg agtggatagt tgtgttttgt 1320 ttgggtggat agtttttttt ttttttatgt tagttttggg gttgttaagt tgtgtagttt 1380 gtgggttggg agtattgaat ggatatagtt taggttgtgg tagggtttag agtgggatgt 1440 tttatggttt ttatttaggt ttggggatat ttttatttgt tttttagaat tgggttgtgg 1500 gggatagaag gggtttgtgt gtgggtaggg agagtatttt ggtttttttt tgtttttggg 1560 gtttataaag tgtgttggga tttgtggggt tgttttgttt aagtttgggt ttggtgtttg 1620 tgtttttgag tttgtgagtg tgtgtgtttt tttgtgtttt tttgattgtt ggtgttgggg 1680 ttttgtgttt tgtgtttgtg ggagtaaata tagtaggtga aggggaagtt tatataatgg 1740 tttttagtgt tttggggtag ggtttttgag gggtgggttt gtttttgttg ggatttggag 1800 tttttgtttt ttggagaggt ttttaggttg atttgggtag agttttttgg tgggttggga 1860 gggggaaagg ttgtgttgaa atgagtaaat tgtttaggtg ttaggttaag ttgggaggtg 1920 attagtttga ggtttttttt gttttatggt tagaattagg gttgatattt gggtgttttg 1980 agtttagttg tttatatggt ttatttgggg ttagttttat ttgagtgggg gaggtggggt 2040 tttttggggg attagaattt tggttggatg ttaagtagag tgttagtggt tgttttttag 2100 ggttgggttt gaggagggtg tggggtggtg aagggatggg agggggttgt gatttagtgg 2160 ttattggtgt tgtgtagagt gtgagttgga aatattgtag ttattttgtt agtttagtgg 2220 tgaaagtttt tttttaggtt ttattttttt gtatttttgt tttttagagg gaggggaggt 2280 ttgggtttgt agagttggga gggtttgttg tttttgtttt ttttttttat aatatttttt 2340 tatttggata tttttgggta tatgt 2365 <210> 15 <211> 2365 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 15 gtatgtgttt aaagatgttt agatgaggag gtgttgtggg ggaggggggt gggaatagta 60 agttttttta gttttgtaga tttagatttt tttttttttt gggaagtagg gatgtaaagg 120 gatagagttt gaaaaagggt ttttattatt aagttgataa agtaattatg atgtttttag 180 tttatatttt gtatagtgtt agtggttatt ggattataat ttttttttgt ttttttgttg 240 ttttatattt tttttaggtt tagttttgaa gaatagttat tggtattttg tttggtgttt 300 agttaaagtt ttggtttttt aggaggtttt gtttttttta tttagatagg gttgatttta 360 ggtgggttgt gtgggtagtt gggtttagga tatttagatg ttagttttgg ttttggttat 420 ggagtgggga ggattttagg ttggttattt tttagtttgg tttgatattt ggatagtttg 480 tttattttaa tatagttttt tttttttttg gtttattaga gggttttgtt taagttagtt 540 taggagtttt tttgaggggt gggggtttta ggttttggta gaggtaggtt tgttttttag 600 aagttttgtt ttagagtgtt ggagattatt gtgtgagttt tttttttgtt tgttgtattt 660 atttttgtgg atgtaggatg tagagtttta gtattggtag ttaagaggat gtaggaaagt 720 gtatgtattt ataggtttag agatgtggat gttagattta ggtttggata gagtagtttt 780 gtaagtttta atatattttg taaattttga agataggaga gagttaaaat attttttttg 840 tttgtatgta ggtttttttt gttttttatg gtttgatttt gggaggtgga tgaggatatt 900 tttaggtttg gatgggggtt atgggatatt ttattttaga ttttgttatg atttgggttg 960 tgtttgtttg gtgtttttgg tttatgggtt gtataatttg gtggttttga aattggtgtg 1020 ggggagggga gggttgttta tttgagtagg atgtggttgt ttatttagtt ggaggtgagg 1080 aatgattttt ttattttgtt gttgggttta agtggggttt gagagttgtt ggggagagtt 1140 aaagggaggg gattgatgga ttttttagag tgaaattgtg tgttttggag agttttgagg 1200 tagttttgtg agtttttgag gaggttgttg ttgtttggta aatataaata ataataaaag 1260 gaaggaaatt taggtggtag tgtgtagaat gagtataggg ttttgtgagg gtgtgtaggg 1320 tttatgtggg tgtttttaat agggtttttt atgtaggtgg tgtgggtatg gggttggggg 1380 tgtgtggtgt ttttagtggg agggtgtttg gattaggggt tttgtttttt tttagtgtat 1440 ttttgttttt ttttagtgta tttttgtttt gtgttaggtt tatttgtagg gtttttttta 1500 gtatgtttgt ggttgtagta gttagtttag tatttatttt tgaagtttga aatgatttta 1560 tttagttgtg tgttgattgt ggggtttgat atgatggttg gtgggtagtg ggttgtgtgg 1620 agggtagtgg tgaggaagtg tttttggtgg ggtttgggtt ttgtgtgttg gttggggtgt 1680 tgtgtttgtg tttttgtagt gtagagttag ttgttggagg agtttttagg ttttttggtt 1740 tagttgaatg aatgggggag gaaggtgggt gttggttttt ttttgtgtgt tgtgtttttg 1800 ttttgttttt gttttttggg tggattaggt ttttgtattt gtattggttt ttttgttttg 1860 tattggttgt tttgtttgtt tgttaaggtt aggtttgggg ggttggggtt tgagtggttg 1920 ttgggggata gttttgggta tatgattgga gtgttttttt tttttttgtt tggtttgtgt 1980 ttaggggatg gtgagagatg tggttttagt tttttttttt gggtgttttg ttgtggttag 2040 atgtgggtgg atgtggaggt tgggttatgg tgaggagggt gggtgtttag aggggaagag 2100 attttttttt ttttttgggt gtagggtttt tttgtaggag gttgtatttg ggtagttaaa 2160 taaagttttt tgttattgtt gttgtgtgtt ttgtgtttgt aagggttaaa tggtagtgta 2220 tgtggttggt aggtaggatt ttggtttgtg ggtttaagag ttgaggggtg tagggtgaat 2280 atgtgagttt tatggtatta gtgagaggtt attaattttt atttattgag ggtatttttg 2340 tagttaatat ttttattatg attat 2365 <210> 16 <211> 3791 <212> DNA <213> Homo Sapiens <400> 16 gccttcctac taccggccca ggattagcgc cctgggagcg cgcgccccgc tgcctcgccg 60 ccacactttc ctgggagcgg cggccacgga ggcaccatga agaagtctta ctcaggaggc 120 acgcggacct ccagtggccg gctccggagg cttggtgact ccagtggccc agccttgaaa 180 agatcttttg aggtcgagga ggtcgagaca cccaactcca ccccaccccg gagggtccag 240 actcccctac tccgagccac tgtggccagc tccacccaga aattccagga cctgggcgtg 300 aagaactcag aaccctcggc ccgccatgtg gactccctaa gccaacgctc ccccaaggcg 360 tccctgcgga gggtggagct ctcgggcccc aaggcggccg agccggtgtc ccggcgcact 420 gagctgtcca ttgacatctc gtccaagcag gtggagaacg ccggggccat cggcccgtcc 480 cggttcgggc tcaagagggc cgaggtgttg ggccacaaga cgccagaacc ggcccctcgg 540 aggacggaga tcaccatcgt caaaccccag gagtcagccc accggaggat ggagccccct 600 gcctccaagg tccccgaggt gcccactgcc cctgccaccg acgcagcccc caagagggtg 660 gagatccaga tgcccaagcc tgctgaggcg cccaccgccc ccagcccagc ccagaccttg 720 gagaattcag agcctgcccc tgtgtctcag ctgcagagca ggctggagcc caagccccag 780 ccccctgtgg ctgaggctac accccggagc caggaggcca ctgaggcggc tcccagctgc 840 gttggcgaca tggccgacac ccccagagat gccgggctca agcaggcgcc tgcatcacgg 900 aacgagaagg ccccggtgga cttcggctac gtggggattg actccatcct ggagcagatg 960 cgccggaagg ccatgaagca gggcttcgag ttcaacatca tggtggtcgg gcagagcggc 1020 ttgggtaaat ccaccttaat caacaccctc ttcaaatcca aaatcagccg gaagtcggtg 1080 cagcccacct cagaggagcg catccccaag accatcgaga tcaagtccat cacgcacgat 1140 attgaggaga aaggcgtccg gatgaagctg acagtgattg acacaccagg gttcggggac 1200 cacatcaaca acgagaactg ctggcagccc atcatgaagt tcatcaatga ccagtacgag 1260 aaatacctgc aggaggaggt caacatcaac cgcaagaagc gcatcccgga cacccgcgtc 1320 cactgctgcc tctacttcat ccccgccacc ggccactccc tcaggcccct ggacatcgag 1380 tttatgaaac gcctgagcaa ggtggtcaac atcgtccctg tcatcgccaa ggcggacaca 1440 ctcaccctgg aggagagggt ccacttcaaa cagcggatca ccgcagacct gctgtccaac 1500 ggcatcgacg tgtaccccca gaaggaattt gatgaggact cggaggaccg gctggtgaac 1560 gagaagttcc gggagatgat cccatttgct gtggtgggca gtgaccacga gtaccaggtc 1620 aacggcaaga ggatccttgg gaggaagacc aagtggggta ccatcgaagt tgaaaacacc 1680 acacactgtg agtttgccta cctgcgggac cttctcatca ggacgcacat gcagaacatc 1740 aaggacatca ccagcagcat ccacttcgag gcgtaccgtg tgaagcgcct caacgagggc 1800 agcagcgcca tggccaacgg catggaggag aaggagccag aagccccgga gatgtagacg 1860 ccaccctgcc cacccccggg atcctgcccc caagtcattt ccgtcccccc ccaggccctc 1920 ccaccacccc attttatttt atatgatttt ctccatttgt catcgttccc caccccttcg 1980 acatgctgcc aggaaacaag ggaaggggcc tccctccgag tgagtcagtg atgaggccgc 2040 ggcctccccg aggttgtggg gaggctgcac tggagccaca ggcaggggtg agagcaccca 2100 ctgaattgac atgaccctct gtccccaggc ctggctcccc gagggctcag aagagcagct 2160 tcggtgtgca gatcatccgt ctgtgtgggg ttctcagtgc cggaggcctt ggggtggggg 2220 ccaggcctcg cacttgcaga ggagcccagt gggctgcacg ctcccctcca tccccatcgg 2280 ccctgtcccc tggagtgtgt cagagcccag gggagaatgc agcccaccag gagcacctgg 2340 accccctgcc cgccacatgg tgtggccatc actcagcccc tacccctgcc ctgctcctaa 2400 gggtagaaaa ctccagggtc ccctgccacc gactgcccag ccactccaag ccccctggca 2460 gctgcccctc ctggagcaga aagtgccttt atctcagcca tccgcagact gcttggccag 2520 atgcggggac aggctggaat gagggaggcg tcttcatctc cctgccatcc ccctctcacg 2580 ccacccccgc ccccaccggg ctgcaggtgc tgctgatgcg ctgggatctg attgaggata 2640 aaaaggaagg agagatgacc cctaccccct catcccccag ttttgaaaag gtctaagcaa 2700 gtgagtctgg tggaggagct gagggaggga gccatggaag gtgccagaag gaaggttggc 2760 gggggcacgt gtgggccgtg gcttgggctg gtcagagtgg cgtgagctgc ccggcgcctg 2820 ccctgcccaa gtgaccaggg aagtgtgtgt gtgtccatgt gtatgcgtgt ccgtctgtct 2880 gtctagtgtc tgggtttggc ccaagactgg gctgtagtta cattaatgcc cagccagcca 2940 cccctgccac tcacccttcc tggcccaggc cttgctgact ctctgagctg gggaggtggg 3000 aggccaggcg agcctgactc tgttgatcta cccgtgcctg ggcccctccc ctcagagccc 3060 atggtaacga acccctagaa aggagagaac gggcgtcagg ggtgcacagt ccacagctga 3120 agagcaaggt ttcgtggcag cacggcccgg cccctcaccc tctgtcccca cgaggggacc 3180 catgggggct gtctttgcag ggcacagatg accaaagtcc cttcctgctt cctgttacct 3240 gtcttgctcc tggggagaaa gaggggcctg atgagactcc actcaggtgc acacatcacc 3300 aggtgcatct gcaggcaccg ggctggctgc ttgcagccag gagaaggtca gcgagaagga 3360 gtgtatgagt gtgagtgtgt gtgcatggaa gttggggcac tgggcgtctg actccctccc 3420 cacccaagag aggaaggacc cctcaccacc cccactggtg agacagttta ctttgccaac 3480 ttgccatgtt tttgccaaaa ccaagatttt gaaggaaatg agtggccagc gccagggccc 3540 aggccatgtg gcctgcccag cctcaatgtc acttggtggc ggggtggggt gggggtgggc 3600 agcagcatcc cagccttgag atgcttcact ttccttctct gtaaccagac tttgaaaaat 3660 tgttcgtttc atcaggctct gttcctcaat ggccttttgc tacgtgcctc ccgagaaatt 3720 tgtctttttg tataaatgac aaagtgttga aaatgtattt cctgaaataa atgtttcaaa 3780 tgcagaaacc c 3791 <210> 17 <211> 3971 <212> DNA <213> Homo Sapiens <400> 17 ccccaggcct ggccttgaca ggcgggcgga gcagccagtg cgagacaggg aggccggtgc 60 gggtgcggga acctgatccg cccgggaggc gggggcgggg cgggggcgca gcgcgcgggg 120 aggggccggc gcccgccttc ctcccccatt cattcagctg agccaggggg cctaggggct 180 cctccggcgg ctagctctgc actgcaggag cgcgggcgcg gcgccccagc cagcgcgcag 240 ggcccgggcc ccgccggggg cgcttcctcg ccgctgccct ccgcgcgacc cgctgcccac 300 cagccatcat gtcggacccc gcggtcaacg cgcagctgga tgggatcatt tcggacttcg 360 aagccttgaa aagatctttt gaggtcgagg aggtcgagac acccaactcc accccacccc 420 ggagggtcca gactccccta ctccgagcca ctgtggccag ctccacccag aaattccagg 480 acctgggcgt gaagaactca gaaccctcgg cccgccatgt ggactcccta agccaacgct 540 cccccaaggc gtccctgcgg agggtggagc tctcgggccc caaggcggcc gagccggtgt 600 cccggcgcac tgagctgtcc attgacatct cgtccaagca ggtggagaac gccggggcca 660 tcggcccgtc ccggttcggg ctcaagaggg ccgaggtgtt gggccacaag acgccagaac 720 cggcccctcg gaggacggag atcaccatcg tcaaacccca ggagtcagcc caccggagga 780 tggagccccc tgcctccaag gtccccgagg tgcccactgc ccctgccacc gacgcagccc 840 ccaagagggt ggagatccag atgcccaagc ctgctgaggc gcccaccgcc cccagcccag 900 cccagacctt ggagaattca gagcctgccc ctgtgtctca gctgcagagc aggctggagc 960 ccaagcccca gccccctgtg gctgaggcta caccccggag ccaggaggcc actgaggcgg 1020 ctcccagctg cgttggcgac atggccgaca cccccagaga tgccgggctc aagcaggcgc 1080 ctgcatcacg gaacgagaag gccccggtgg acttcggcta cgtggggatt gactccatcc 1140 tggagcagat gcgccggaag gccatgaagc agggcttcga gttcaacatc atggtggtcg 1200 ggcagagcgg cttgggtaaa tccaccttaa tcaacaccct cttcaaatcc aaaatcagcc 1260 ggaagtcggt gcagcccacc tcagaggagc gcatccccaa gaccatcgag atcaagtcca 1320 tcacgcacga tattgaggag aaaggcgtcc ggatgaagct gacagtgatt gacacaccag 1380 ggttcgggga ccacatcaac aacgagaact gctggcagcc catcatgaag ttcatcaatg 1440 accagtacga gaaatacctg caggaggagg tcaacatcaa ccgcaagaag cgcatcccgg 1500 acacccgcgt ccactgctgc ctctacttca tccccgccac cggccactcc ctcaggcccc 1560 tggacatcga gtttatgaaa cgcctgagca aggtggtcaa catcgtccct gtcatcgcca 1620 aggcggacac actcaccctg gaggagaggg tccacttcaa acagcggatc accgcagacc 1680 tgctgtccaa cggcatcgac gtgtaccccc agaaggaatt tgatgaggac tcggaggacc 1740 ggctggtgaa cgagaagttc cgggagatga tcccatttgc tgtggtgggc agtgaccacg 1800 agtaccaggt caacggcaag aggatccttg ggaggaagac caagtggggt accatcgaag 1860 ttgaaaacac cacacactgt gagtttgcct acctgcggga ccttctcatc aggacgcaca 1920 tgcagaacat caaggacatc accagcagca tccacttcga ggcgtaccgt gtgaagcgcc 1980 tcaacgaggg cagcagcgcc atggccaacg gcatggagga gaaggagcca gaagccccgg 2040 agatgtagac gccaccctgc ccacccccgg gatcctgccc ccaagtcatt tccgtccccc 2100 cccaggccct cccaccaccc cattttattt tatatgattt tctccatttg tcatcgttcc 2160 ccaccccttc gacatgctgc caggaaacaa gggaaggggc ctccctccga gtgagtcagt 2220 gatgaggccg cggcctcccc gaggttgtgg ggaggctgca ctggagccac aggcaggggt 2280 gagagcaccc actgaattga catgaccctc tgtccccagg cctggctccc cgagggctca 2340 gaagagcagc ttcggtgtgc agatcatccg tgtggggttc tcagtgccgg atggggtggg 2400 ggccaggcct cgcacttgca gaggagccca gtgggctgca cgctcccctc catccccatc 2460 ggccctgtcc cctggagtgt gtcagagccc aggggagaat gcagcccacc aggagcacct 2520 ggaccccctg cccgccacat ggtgtggcca tcactcagcc cctacccctg ccctgctcct 2580 aagggtagaa aactccaggg tcccctgcca ccgactgccc agccactcca agccccctgg 2640 cagctgcccc tcctggagca gaaagtgcct ttatctcagc catccgcaga ctggccagat 2700 gcggggacag gctggaatga gggaggcgtc ttcatctccc tgccatcccc ctctcacgcc 2760 acccccgccc ccaccgggct gcaggtgctg ctgatgcgct gggatctgat tgaggataaa 2820 aaggaaggag agatgacccc taccccctca tcccccagtt ttgaaaaggt ctaagcaagt 2880 gagtctggtg gaggagctga gggagggagc catggaaggt gccagaagga aggttggcgg 2940 gggcacgtgt gggccgtggc ttgggctggt cagagtggcg tgagctgccc ggcgcctgcc 3000 ctgcccaagt gaccagggaa gtgtgtgtgt gtccatgtgt atgcgtgtcc gtctgtctgt 3060 ctagtgtctg ggtttggccc aagactgggc tgtagttaca ttaatgccca gccagccacc 3120 cctgccactc acccttcctg gcccaggcct tgctgactct ctgagctggg gaggtgggag 3180 gccaggcgag cctgactctg ttgatctacc cgtgcctggg cccctcccct cagagcccat 3240 ggtaacgaac ccctagaaag gagagaacgg gcgtcagggg tgcacagtcc acagctgaag 3300 agcaaggttt cgtggcagca cggcccggcc cctcaccctc tgtccccacg aggggaccca 3360 tgggggctgt ctttgcaggg cacagatgac caaagtccct tcctgcttcc tgttacctgt 3420 cttgctcctg gggagaaaga ggggcctgat gagactccac tcaggtgcac acatcaccag 3480 gtgcatctgc aggcaccggg ctggctgctt gcagccagga gaaggtcagc gagaaggagt 3540 gtatgagtgt gagtgtgtgt gcatggaagt tggggcactg ggcgtctgac tccctcccca 3600 cccaagagag gaaggacccc tcaccacccc cactggtgag acagtttact ttgccaactt 3660 gccatgtttt tgccaaaacc aagattttga aggaaatgag tggccagcgc cagggcccag 3720 gccatgtggc ctgcccagcc tcaatgtcac ttggtggcgg ggtggggtgg gggtgggcag 3780 cagcatccca gccttgagat gcttcacttt ccttctctgt aaccagactt tgaaaaattg 3840 ttcgtttcat caggctctgt tcctcaatgg ccttttgcta cgtgcctccc gagaaatttg 3900 tctttttgta taaatgacaa agtgttgaaa atgtatttcc tgaaataaat gtttcaaatg 3960 cagaaaccca g 3971 <210> 18 <211> 3921 <212> DNA <213> Homo Sapiens <400> 18 gttggcccgg ggccttcagt ggcctttgtg tctgggtgag aggaaccctg gatggccact 60 ctgccctgag tgtgtgggtc cccagaagtg ctgggttagg gggcacggag ggccagaaag 120 tcccctttgg agcgctggac tctctcgctg actcctaccc caccccggcc tggggtttca 180 gagaaggggt ccaggcagga gtgtcatctt ttctcaatgg ggatgtggct tcagtctctg 240 tccaggaggc acgcggacct ccagtggccg gctccggagg cttggtgact ccagtggccc 300 agccttgaaa agatcttttg aggtcgagga ggtcgagaca cccaactcca ccccaccccg 360 gagggtccag actcccctac tccgagccac tgtggccagc tccacccaga aattccagga 420 cctgggcgtg aagaactcag aaccctcggc ccgccatgtg gactccctaa gccaacgctc 480 ccccaaggcg tccctgcgga gggtggagct ctcgggcccc aaggcggccg agccggtgtc 540 ccggcgcact gagctgtcca ttgacatctc gtccaagcag gtggagaacg ccggggccat 600 cggcccgtcc cggttcgggc tcaagagggc cgaggtgttg ggccacaaga cgccagaacc 660 ggcccctcgg aggacggaga tcaccatcgt caaaccccag gagtcagccc accggaggat 720 ggagccccct gcctccaagg tccccgaggt gcccactgcc cctgccaccg acgcagcccc 780 caagagggtg gagatccaga tgcccaagcc tgctgaggcg cccaccgccc ccagcccagc 840 ccagaccttg gagaattcag agcctgcccc tgtgtctcag ctgcagagca ggctggagcc 900 caagccccag ccccctgtgg ctgaggctac accccggagc caggaggcca ctgaggcggc 960 tcccagctgc gttggcgaca tggccgacac ccccagagat gccgggctca agcaggcgcc 1020 tgcatcacgg aacgagaagg ccccggtgga cttcggctac gtggggattg actccatcct 1080 ggagcagatg cgccggaagg ccatgaagca gggcttcgag ttcaacatca tggtggtcgg 1140 gcagagcggc ttgggtaaat ccaccttaat caacaccctc ttcaaatcca aaatcagccg 1200 gaagtcggtg cagcccacct cagaggagcg catccccaag accatcgaga tcaagtccat 1260 cacgcacgat attgaggaga aaggcgtccg gatgaagctg acagtgattg acacaccagg 1320 gttcggggac cacatcaaca acgagaactg ctggcagccc atcatgaagt tcatcaatga 1380 ccagtacgag aaatacctgc aggaggaggt caacatcaac cgcaagaagc gcatcccgga 1440 cacccgcgtc cactgctgcc tctacttcat ccccgccacc ggccactccc tcaggcccct 1500 ggacatcgag tttatgaaac gcctgagcaa ggtggtcaac atcgtccctg tcatcgccaa 1560 ggcggacaca ctcaccctgg aggagagggt ccacttcaaa cagcggatca ccgcagacct 1620 gctgtccaac ggcatcgacg tgtaccccca gaaggaattt gatgaggact cggaggaccg 1680 gctggtgaac gagaagttcc gggagatgat cccatttgct gtggtgggca gtgaccacga 1740 gtaccaggtc aacggcaaga ggatccttgg gaggaagacc aagtggggta ccatcgaagt 1800 tgaaaacacc acacactgtg agtttgccta cctgcgggac cttctcatca ggacgcacat 1860 gcagaacatc aaggacatca ccagcagcat ccacttcgag gcgtaccgtg tgaagcgcct 1920 caacgagggc agcagcgcca tggccaacgg catggaggag aaggagccag aagccccgga 1980 gatgtagacg ccaccctgcc cacccccggg atcctgcccc caagtcattt ccgtcccccc 2040 ccaggccctc ccaccacccc attttatttt atatgatttt ctccatttgt catcgttccc 2100 caccccttcg acatgctgcc aggaaacaag ggaaggggcc tccctccgag tgagtcagtg 2160 atgaggccgc ggcctccccg aggttgtggg gaggctgcac tggagccaca ggcaggggtg 2220 agagcaccca ctgaattgac atgaccctct gtccccaggc ctggctcccc gagggctcag 2280 aagagcagct tcggtgtgca gatcatccgt ctgtgtgggg ttctcagtgc cggaggcctt 2340 ggggtggggg ccaggcctcg cacttgcaga ggagcccagt gggctgcacg ctcccctcca 2400 tccccatcgg ccctgtcccc tggagtgtgt cagagcccag gggagaatgc agcccaccag 2460 gagcacctgg accccctgcc cgccacatgg tgtggccatc actcagcccc tacccctgcc 2520 ctgctcctaa gggtagaaaa ctccagggtc ccctgccacc gactgcccag ccactccaag 2580 ccccctggca gctgcccctc ctggagcaga aagtgccttt atctcagcca tccgcagact 2640 gcttggccag atgcggggac aggctggaat gagggaggcg tcttcatctc cctgccatcc 2700 ccctctcacg ccacccccgc ccccaccggg ctgcaggtgc tgctgatgcg ctgggatctg 2760 attgaggata aaaaggaagg agagatgacc cctaccccct catcccccag ttttgaaaag 2820 gtctaagcaa gtgagtctgg tggaggagct gagggaggga gccatggaag gtgccagaag 2880 gaaggttggc gggggcacgt gtgggccgtg gcttgggctg gtcagagtgg cgtgagctgc 2940 ccggcgcctg ccctgcccaa gtgaccaggg aagtgtgtgt gtgtccatgt gtatgcgtgt 3000 ccgtctgtct gtctagtgtc tgggtttggc ccaagactgg gctgtagtta cattaatgcc 3060 cagccagcca cccctgccac tcacccttcc tggcccaggc cttgctgact ctctgagctg 3120 gggaggtggg aggccaggcg agcctgactc tgttgatcta cccgtgcctg ggcccctccc 3180 ctcagagccc atggtaacga acccctagaa aggagagaac gggcgtcagg ggtgcacagt 3240 ccacagctga agagcaaggt ttcgtggcag cacggcccgg cccctcaccc tctgtcccca 3300 cgaggggacc catgggggct gtctttgcag ggcacagatg accaaagtcc cttcctgctt 3360 cctgttacct gtcttgctcc tggggagaaa gaggggcctg atgagactcc actcaggtgc 3420 acacatcacc aggtgcatct gcaggcaccg ggctggctgc ttgcagccag gagaaggtca 3480 gcgagaagga gtgtatgagt gtgagtgtgt gtgcatggaa gttggggcac tgggcgtctg 3540 actccctccc cacccaagag aggaaggacc cctcaccacc cccactggtg agacagttta 3600 ctttgccaac ttgccatgtt tttgccaaaa ccaagatttt gaaggaaatg agtggccagc 3660 gccagggccc aggccatgtg gcctgcccag cctcaatgtc acttggtggc ggggtggggt 3720 gggggtgggc agcagcatcc cagccttgag atgcttcact ttccttctct gtaaccagac 3780 tttgaaaaat tgttcgtttc atcaggctct gttcctcaat ggccttttgc tacgtgcctc 3840 ccgagaaatt tgtctttttg tataaatgac aaagtgttga aaatgtattt cctgaaataa 3900 atgtttcaaa tgcagaaacc c 3921 <210> 19 <211> 1328 <212> DNA <213> Homo Sapiens <400> 19 cgggactccc gccgctgcta aatatatccg taggaatgga gagggaccgg atctcagcct 60 tgaaaagatc ttttgaggtc gaggaggtcg agacacccaa ctccacccca ccccggaggg 120 tccagactcc cctactccga gccactgtgg ccagctccac ccagaaattc caggacctgg 180 gcgtgaagaa ctcagaaccc tcggcccgcc atgtggactc cctaagccaa cgctccccca 240 aggcgtccct gcggagggtg gagctctcgg gccccaaggc ggccgagccg gtgtcccggc 300 gcactgagct gtccattgac atctcgtcca agcaggtgga gaacgccggg gccatcggcc 360 cgtcccggtt cgggctcaag agggccgagg tgttgggcca caagacgcca gaaccggccc 420 ctcggaggac ggagatcacc atcgtcaaac cccaggagtc agcccaccgg aggatggagc 480 cccctgcctc caaggtcccc gaggtgccca ctgcccctgc caccgacgca gcccccaaga 540 gggtggagat ccagatgccc aagcctgctg aggcgcccac cgcccccagc ccagcccaga 600 ccttggagaa ttcagagcct gcccctgtgt ctcagctgca gagcaggctg gagcccaagc 660 cccagccccc tgtggctgag gctacacccc ggagccagga ggccactgag gcggctccca 720 gctgcgttgg cgacatggcc gacaccccca gagatgccgg gctcaagcag gcgcctgcat 780 cacggaacga gaaggccccg gtggacttcg gctacgtggg gattgactcc atcctggagc 840 agatgcgccg gaaggccatg aagcagggct tcgagttcaa catcatggtg gtcgggcaga 900 gcggcttggg taaatccacc ttaatcaaca ccctcttcaa atccaaaatc agccggaagt 960 cggtgcagcc cacctcagag gagcgcatcc ccaagaccat cgagatcaag tccatcacgc 1020 acgatattga ggagaaaggc gtccggatga agctgacagt gattgacaca ccagggttcg 1080 gggaccacat caacaacgag aactgctggc agcccatcat gaagttcatc aatgaccagt 1140 acgagaaata cctgcaggag gaggtcaaca tcaaccgcaa gaagcgcatc ccggacaccc 1200 gcgtccactg ctgcctctac ttcatccccg ccaccggcca ctcgtacctg cccctcctgg 1260 agcagaaagt gcctttatct cagccatccg cagactgctt ggccagatgc ggggacaggc 1320 tggaatga 1328 <210> 20 <211> 586 <212> PRT <213> Homo sapiens <400> 20 Met Lys Lys Ser Tyr Ser Gly Gly Thr Arg Thr Ser Ser Gly Arg Leu 1 5 10 15 Arg Arg Leu Gly Asp Ser Ser Gly Pro Ala Leu Lys Arg Ser Phe Glu 20 25 30 Val Glu Glu Val Glu Thr Pro Asn Ser Thr Pro Pro Arg Arg Val Gln 35 40 45 Thr Pro Leu Leu Arg Ala Thr Val Ala Ser Ser Thr Gln Lys Phe Gln 50 55 60 Asp Leu Gly Val Lys Asn Ser Glu Pro Ser Ala Arg His Val Asp Ser 65 70 75 80 Leu Ser Gln Arg Ser Pro Lys Ala Ser Leu Arg Arg Val Glu Leu Ser 85 90 95 Gly Pro Lys Ala Ala Glu Pro Val Ser Arg Arg Thr Glu Leu Ser Ile 100 105 110 Asp Ile Ser Ser Lys Gln Val Glu Asn Ala Gly Ala Ile Gly Pro Ser 115 120 125 Arg Phe Gly Leu Lys Arg Ala Glu Val Leu Gly His Lys Thr Pro Glu 130 135 140 Pro Ala Pro Arg Arg Thr Glu Ile Thr Ile Val Lys Pro Gln Glu Ser 145 150 155 160 Ala His Arg Arg Met Glu Pro Pro Ala Ser Lys Val Pro Glu Val Pro 165 170 175 Thr Ala Pro Ala Thr Asp Ala Ala Pro Lys Arg Val Glu Ile Gln Met 180 185 190 Pro Lys Pro Ala Glu Ala Pro Thr Ala Pro Ser Pro Ala Gln Thr Leu 195 200 205 Glu Asn Ser Glu Pro Ala Pro Val Ser Gln Leu Gln Ser Arg Leu Glu 210 215 220 Pro Lys Pro Gln Pro Pro Val Ala Glu Ala Thr Pro Arg Ser Gln Glu 225 230 235 240 Ala Thr Glu Ala Ala Pro Ser Cys Val Gly Asp Met Ala Asp Thr Pro 245 250 255 Arg Asp Ala Gly Leu Lys Gln Ala Pro Ala Ser Arg Asn Glu Lys Ala 260 265 270 Pro Val Asp Phe Gly Tyr Val Gly Ile Asp Ser Ile Leu Glu Gln Met 275 280 285 Arg Arg Lys Ala Met Lys Gln Gly Phe Glu Phe Asn Ile Met Val Val 290 295 300 Gly Gln Ser Gly Leu Gly Lys Ser Thr Leu Ile Asn Thr Leu Phe Lys 305 310 315 320 Ser Lys Ile Ser Arg Lys Ser Val Gln Pro Thr Ser Glu Glu Arg Ile 325 330 335 Pro Lys Thr Ile Glu Ile Lys Ser Ile Thr His Asp Ile Glu Glu Lys 340 345 350 Gly Val Arg Met Lys Leu Thr Val Ile Asp Thr Pro Gly Phe Gly Asp 355 360 365 His Ile Asn Asn Glu Asn Cys Trp Gln Pro Ile Met Lys Phe Ile Asn 370 375 380 Asp Gln Tyr Glu Lys Tyr Leu Gln Glu Glu Val Asn Ile Asn Arg Lys 385 390 395 400 Lys Arg Ile Pro Asp Thr Arg Val His Cys Cys Leu Tyr Phe Ile Pro 405 410 415 Ala Thr Gly His Ser Leu Arg Pro Leu Asp Ile Glu Phe Met Lys Arg 420 425 430 Leu Ser Lys Val Val Asn Ile Val Pro Val Ile Ala Lys Ala Asp Thr 435 440 445 Leu Thr Leu Glu Glu Arg Val His Phe Lys Gln Arg Ile Thr Ala Asp 450 455 460 Leu Leu Ser Asn Gly Ile Asp Val Tyr Pro Gln Lys Glu Phe Asp Glu 465 470 475 480 Asp Ser Glu Asp Arg Leu Val Asn Glu Lys Phe Arg Glu Met Ile Pro 485 490 495 Phe Ala Val Val Gly Ser Asp His Glu Tyr Gln Val Asn Gly Lys Arg 500 505 510 Ile Leu Gly Arg Lys Thr Lys Trp Gly Thr Ile Glu Val Glu Asn Thr 515 520 525 Thr His Cys Glu Phe Ala Tyr Leu Arg Asp Leu Leu Ile Arg Thr His 530 535 540 Met Gln Asn Ile Lys Asp Ile Thr Ser Ser Ile His Phe Glu Ala Tyr 545 550 555 560 Arg Val Lys Arg Leu Asn Glu Gly Ser Ser Ala Met Ala Asn Gly Met 565 570 575 Glu Glu Lys Glu Pro Glu Ala Pro Glu Met 580 585 <210> 21 <211> 190 <212> PRT <213> Homo sapiens <400> 21 Met Thr Leu Cys Pro Gln Ala Trp Leu Pro Glu Gly Ser Glu Glu Gln 1 5 10 15 Leu Arg Cys Ala Asp His Pro Cys Gly Val Leu Ser Ala Gly Trp Gly 20 25 30 Gly Gly Gln Ala Ser His Leu Gln Arg Ser Pro Val Gly Cys Thr Leu 35 40 45 Pro Ser Ile Pro Ile Gly Pro Val Pro Trp Ser Val Ser Glu Pro Arg 50 55 60 Gly Glu Cys Ser Pro Pro Gly Ala Pro Gly Pro Pro Ala Arg His Met 65 70 75 80 Val Trp Pro Ser Leu Ser Pro Tyr Pro Cys Pro Ala Pro Lys Gly Arg 85 90 95 Lys Leu Gln Gly Pro Leu Pro Pro Thr Ala Gln Pro Leu Gln Ala Pro 100 105 110 Trp Gln Leu Pro Leu Leu Glu Gln Lys Val Pro Leu Ser Gln Pro Ser 115 120 125 Ala Asp Trp Pro Asp Ala Gly Thr Gly Trp Asn Glu Gly Gly Val Phe 130 135 140 Ile Ser Leu Pro Ser Pro Ser His Ala Thr Pro Ala Pro Thr Gly Leu 145 150 155 160 Gln Val Leu Leu Met Arg Trp Asp Leu Ile Glu Asp Lys Lys Glu Gly 165 170 175 Glu Met Thr Pro Thr Pro Ser Ser Pro Ser Phe Glu Lys Val 180 185 190 <210> 22 <211> 422 <212> PRT <213> Homo sapiens <400> 22 Met Glu Pro Pro Ala Ser Lys Val Pro Glu Val Pro Thr Ala Pro Ala 1 5 10 15 Thr Asp Ala Ala Pro Lys Arg Val Glu Ile Gln Met Pro Lys Pro Ala 20 25 30 Glu Ala Pro Thr Ala Pro Ser Pro Ala Gln Thr Leu Glu Asn Ser Glu 35 40 45 Pro Ala Pro Val Ser Gln Leu Gln Ser Arg Leu Glu Pro Lys Pro Gln 50 55 60 Pro Pro Val Ala Glu Ala Thr Pro Arg Ser Gln Glu Ala Thr Glu Ala 65 70 75 80 Ala Pro Ser Cys Val Gly Asp Met Ala Asp Thr Pro Arg Asp Ala Gly 85 90 95 Leu Lys Gln Ala Pro Ala Ser Arg Asn Glu Lys Ala Pro Val Asp Phe 100 105 110 Gly Tyr Val Gly Ile Asp Ser Ile Leu Glu Gln Met Arg Arg Lys Ala 115 120 125 Met Lys Gln Gly Phe Glu Phe Asn Ile Met Val Val Gly Gln Ser Gly 130 135 140 Leu Gly Lys Ser Thr Leu Ile Asn Thr Leu Phe Lys Ser Lys Ile Ser 145 150 155 160 Arg Lys Ser Val Gln Pro Thr Ser Glu Glu Arg Ile Pro Lys Thr Ile 165 170 175 Glu Ile Lys Ser Ile Thr His Asp Ile Glu Glu Lys Gly Val Arg Met 180 185 190 Lys Leu Thr Val Ile Asp Thr Pro Gly Phe Gly Asp His Ile Asn Asn 195 200 205 Glu Asn Cys Trp Gln Pro Ile Met Lys Phe Ile Asn Asp Gln Tyr Glu 210 215 220 Lys Tyr Leu Gln Glu Glu Val Asn Ile Asn Arg Lys Lys Arg Ile Pro 225 230 235 240 Asp Thr Arg Val His Cys Cys Leu Tyr Phe Ile Pro Ala Thr Gly His 245 250 255 Ser Leu Arg Pro Leu Asp Ile Glu Phe Met Lys Arg Leu Ser Lys Val 260 265 270 Val Asn Ile Val Pro Val Ile Ala Lys Ala Asp Thr Leu Thr Leu Glu 275 280 285 Glu Arg Val His Phe Lys Gln Arg Ile Thr Ala Asp Leu Leu Ser Asn 290 295 300 Gly Ile Asp Val Tyr Pro Gln Lys Glu Phe Asp Glu Asp Ser Glu Asp 305 310 315 320 Arg Leu Val Asn Glu Lys Phe Arg Glu Met Ile Pro Phe Ala Val Val 325 330 335 Gly Ser Asp His Glu Tyr Gln Val Asn Gly Lys Arg Ile Leu Gly Arg 340 345 350 Lys Thr Lys Trp Gly Thr Ile Glu Val Glu Asn Thr Thr His Cys Glu 355 360 365 Phe Ala Tyr Leu Arg Asp Leu Leu Ile Arg Thr His Met Gln Asn Ile 370 375 380 Lys Asp Ile Thr Ser Ser Ile His Phe Glu Ala Tyr Arg Val Lys Arg 385 390 395 400 Leu Asn Glu Gly Ser Ser Ala Met Ala Asn Gly Met Glu Glu Lys Glu 405 410 415 Pro Glu Ala Pro Glu Met 420 <210> 23 <211> 197 <212> PRT <213> Homo sapiens <400> 23 Met Ala Asp Thr Pro Arg Asp Ala Gly Leu Lys Gln Ala Pro Ala Ser 1 5 10 15 Arg Asn Glu Lys Ala Pro Val Asp Phe Gly Tyr Val Gly Ile Asp Ser 20 25 30 Ile Leu Glu Gln Met Arg Arg Lys Ala Met Lys Gln Gly Phe Glu Phe 35 40 45 Asn Ile Met Val Val Gly Gln Ser Gly Leu Gly Lys Ser Thr Leu Ile 50 55 60 Asn Thr Leu Phe Lys Ser Lys Ile Ser Arg Lys Ser Val Gln Pro Thr 65 70 75 80 Ser Glu Glu Arg Ile Pro Lys Thr Ile Glu Ile Lys Ser Ile Thr His 85 90 95 Asp Ile Glu Glu Lys Gly Val Arg Met Lys Leu Thr Val Ile Asp Thr 100 105 110 Pro Gly Phe Gly Asp His Ile Asn Asn Glu Asn Cys Trp Gln Pro Ile 115 120 125 Met Lys Phe Ile Asn Asp Gln Tyr Glu Lys Tyr Leu Gln Glu Glu Val 130 135 140 Asn Ile Asn Arg Lys Lys Arg Ile Pro Asp Thr Arg Val His Cys Cys 145 150 155 160 Leu Tyr Phe Ile Pro Ala Thr Gly His Ser Tyr Leu Pro Leu Leu Glu 165 170 175 Gln Lys Val Pro Leu Ser Gln Pro Ser Ala Asp Cys Leu Ala Arg Cys 180 185 190 Gly Asp Arg Leu Glu 195 <210> 24 <211> 2804 <212> DNA <213> Homo Sapiens <400> 24 ccaaggcccg ccggacctga ggtcgcctgg ggcgctaaac agacccatct atgagcacat 60 tcggccaaca cacccaagtt caacagtggg cgggatcttt ggctggcctc gatctctctc 120 acagtgtgtg caaacgggta cccattagat tctttttgct tgtttcctca tctgtaaact 180 ttgaaaggag agtatttccc ggggtgattc tgaaaatcat gccagaactg aaaaggcctg 240 tgtaaatgcg aggtgtaatg atgacttatt agaagcagcc agccctgtac gtgcctgtag 300 gatagatgct agaacgttct acaaatgtgt gcacatacac atcacgtatg tgtgaaggtg 360 cacacctgtc cctagacact tgacaaatgc acacacgtat gcgtgtacct ctggctgaga 420 gcaaaggggc taatacaggg ctcatacagg acatcatcct gcagtcttgt gcgtgcacag 480 tacacacgcg agcacgactg tctgtgcctg gagacaccgt atggcaccgg aggagctgct 540 cagccgtcgg tgccacctgg gaagtagggt ttcgggtgct gctctggagc gcgggaaagt 600 ccggatccgg gtctgctggt cagcgcttcg gcgccgccgg gctcctttat ctctcatccg 660 ccggccggtg agcggctcca gtttcaagac ccccgatcct gccggtgagg ggagggagcg 720 agaaggagtg cgctccgggc ccaagaggct gcagggcccc actccccagg tctgtcgtcc 780 ttcctttatc tcctcaggtc acacccccac ttaaaataaa gaagggtgcc tgactcattc 840 aggtcaggga agtcggcccc cgggagcctc ctgccctcac aagccatggt gaagggaggc 900 gaagccaggg tttgccacgg cctgggagaa aatgcggctg cagggtctct ttgggctgca 960 gcgctggccc ggggccccaa gactgttaag gtgtgtgtgg gaggcgcgca gtgtggctac 1020 cgaagagccc tccatcaccg caccggcagg ccgccgggct cgtcctcctc tcatgcttcc 1080 aagggttctg agctgcgcag cactcgcatc acccagaagt gtctgtggag aaaacgacct 1140 caggtgtaag cccaaggctg ctgcctgcaa aggcaatgcc gtggagactg ggttccacag 1200 cgacctgggt ttttaagtca ccgaaagcta cagggcaggg tcacaaacac tctcccgcct 1260 tctctgcaga accgtgcggc tgacaggaga gcgttgcgca gaaaattcga ggccgggcgc 1320 tggaggagtc tccgcggccc ggagaaggca cagaggcgcc cctgagaggc gcagctggaa 1380 caggcgatgc acgggttcgg atctggccgg ccaaccgagc ccagcggtcg cgaaaaccag 1440 agtcgccaca gaggttgagc acgattccat ttctggggat cgggtccggt ggggagccac 1500 tgtccctaac gcctccagag actttaagta ggacaatata atgctggtag gagcaaggtg 1560 caaggaattt agcggcagaa gcctttcggg ggggtgggga aaggcagatc cgtgcctcgt 1620 ctgagcctgg gggtggggac agcccctggc cttgtagccc ctgttccggg gatcagctgg 1680 gcccacctaa cccccctaca tggggttgaa aggggccaat gggacggccc cgccgcccct 1740 ccctcgggat tccacagggc cctgacccgg cctttatctc tgcacggtca gcagtcgcgg 1800 gggcttcagg aaggaggaca aaggcccggt gtcaccgcgg gcgggggctc ggtttcctgg 1860 ctctctgctc acactcacag cctttagcgg ttgttggggg aagattttta aaaatatgtg 1920 tcgaatttcc tttttttctc ttctagaaac aaacaaacaa aaaaggcaaa aggcgaattc 1980 cccttcactc ctcgtccata gagattaaag tttcctggga tcctgccctt tttttttctt 2040 tgactgccta gaaatacttg ttctcccttg tacatagagg aaaatgcggg gaaaggtttt 2100 ttaaaactcg gtttcatact attattatta ctaaggacaa ccgggcaggc tgaggtccca 2160 acgtggatga tccgagttgg cctcgcgccg gggctctgca gccactgccc tgtgcgctca 2220 gcacctctgg gggcgatcag ggcccctgcg cttccgcccg ccgcccggca gtcgagagca 2280 ccctgtgccc agactggccg actcattctc ccccgaattt tgtttagagc tggcaagggg 2340 gacttagctc gcgccccaag acctgggctt gcagcgccgc caacaggccc ggggacacga 2400 ggcgctccag gccggggtct tcccggctgc tggcccctct cgctccccac ccgctggcgg 2460 cgcctcggtc gcccgcaatt gacccaaccc gcttcctgcg tttgcccctc aggtttcccg 2520 tttctccaca aaggcctagg ggagcctcgc ccacaggctg accctgcaac ctctggcccg 2580 gtggctacct tctgcttttc tgaaaaagaa aaggaaaaaa aaaaaaaaaa agaaaaaatc 2640 aaccagtcga gggaggcgcg tgaggactgg aggcgccagc cggacagcct atgagtaggt 2700 ccctgggtcg gtgccgcttc gcgggtcagc acggcctttc tcagagaaaa cctcctaaac 2760 gtgtgaagac cgctttgggg gaagcgagag ggaggttgga ggag 2804 <210> 25 <211> 3952 <212> DNA <213> Homo Sapiens <400> 25 ggccgcagcc ggagaggaac aggaaccgca gtggggacgc cctggtcccc gggcccacag 60 catccgggac ggacgcgcag tagcgcgggc cgggaactgg gtaccagggc gggatgggtg 120 agaggctcta agggacaagg cagggagaag cgcagcgggg tgcggggaac cgcacgccct 180 ccctttgcct ctgcttccca ccccgaggcg gcagggcggg cgggcgcggt tccgggggtg 240 ggcgggctgg gcggggcgga ggcggggccg cagcactggc ttcacccagc ctctcccgcc 300 cgcagccaga gcgagccgag ccgcggccag ctccggcggg cagggggggc gctggagcgc 360 agcgcagcgc agccccatca gtccgcaaag cggaccgagc tggaagtcga gcgctgccgc 420 gggaggcggg cgatgggggc aggtgccacc ggccgcgcca tggacgggcc gcgcctgctg 480 ctgttgctgc ttctgggggt gagtgttagc cggagggggc ccgctccctt tcccgggatc 540 agaactccga gaagagccgg gcgccgccac caaggaaaca gaacagagca ttggggtccc 600 agatactgag ggtgggtggt gggaaaggac ctctgatgcc gggaccacga aggagggtct 660 agggttcccg gagcgcagag gcgactctcc agggtggaga tgagggcaag accggagcac 720 ggatgccggt cctcaggtac cgcagggggc ggtgggggag ctgggagggg tctttcaaga 780 gggggcatgg ggctctccga tgcccaggtt cttcggaaga ggacactcga atgccgggat 840 cccgaaggga ctttcccctc agcatctcgg tctctggaga gtcgtgggac agaaccaagg 900 cgagagaagg agggggaact ggacggggac tagagatgag aggggcgagc tgggctgggg 960 cggggagccc gggacgacgg gatggaacaa tggaggaggt cggagggact ggaggcagag 1020 gggacccggc aaggacaatg gggaccggcc agacaatggg ggggaggggc gtcggaggga 1080 gaggttgggg agcgggagag aggttgagaa gtgggttagg gagggcagaa gaggggcgac 1140 ggcgagggcg gcagagagat ggaagcagaa ggaaaggaga cagagcgggg cgcggaccct 1200 gaagtggtcg gggtcccgcc tgcccgctga gggacagtga gacgagaaga gagagcagag 1260 gcttggacat ttccagcgcc tgtccccgcg ctcctgctcg cggcctctcc cagtcccgga 1320 attggggctg cggatctaag gctgggaggg gagtgcccac ttcgccgggg cgaacccgct 1380 cccggggttc ccccacggcc ggcgggctcc tccgacgcgc gtgttctcac ggcttgaagc 1440 agcgcagcgg atcgcgaggg acggagcggg tgtgccccta cccgggctgg cggtggctac 1500 gtctcggggt gcagagcgcc ggggcgcact aggcggggac ccttcctggc cgcgcgcagc 1560 tctggctacg caggcgggag gcggcaggca gggggcgctg cggggcgagg caagtgcagt 1620 ccgccgctgc ctgcctgcga gtctggggct gcgcgccgct ccccacctag ctgcgcgacc 1680 cgagcgccgc gcccaccgcg ctccgtgggc tcccgcgcct cgaagggtcg ggatccggtc 1740 tgagcctctc ctggctctcg gtgcaagccg ctgggcacct aacgagacgg gggcgcccgg 1800 acgcctcgga ttctgtagcg cggtatcccg ggccaccgac tcggcaaagg tcggcgggtc 1860 ctccgggtgg tccgacgaga ttgtcagatg tggcctgctt tatggccatg aaccgaatgc 1920 cctggaaggt ctggcaacgg aggaggcgtc ttcactctcc ccgccagcat ctttcatcag 1980 agcactgcgc cccaaattcc ggctttacag atacggagac tgaggctctg agagtttaaa 2040 cgacttggcc aagatctcac agcaagttgg gccagagtcg tggctagact ccccgacctg 2100 attcccagct cggtactccc ccaccttttc agggggcagc cgctgtccca gctcggggtc 2160 acggctgcgt ttcccagcag ggcggggggg gttgacactg tccccagagt ccgtcggcgg 2220 tagagcctgc gggtgaggtg ggcagagatt ctgtccgggt gcgggcccca gcccgaaagc 2280 tcagccccag ttccctggag ctgtcaggac ctgtggctgc gtccggggat ttgggagcga 2340 ccgcgggcac gtctgctgac taacgccgct ggttagagac gctgctcaga cgcgggtggg 2400 cgagcgtaga ccaggagagc ggggaggagg gaccggatcc cagaggggca acgacttggg 2460 ctccgggtct gggcaagagc gagggtcccc gcgcgaagac ccaaggaagg aggggagctg 2520 ggcgtggagg acctgggcgc ttgggaaggt gtaccccgac aggaacctgc cgtctgcagc 2580 ccctgcggct cccgcctccg cctcggcgcg cggctgctcg gtctgggatg gctgtgcgcg 2640 gtccgagttt cttcctgggc cgcggtgaga gagagagggc tgaaaccaga gcgcgtcccg 2700 gcgggtcggc tggcgggccg cgccggtaat ggaggcactt tgtcattcag acgtctgtaa 2760 ccagagccgc cgggctggct aatgcgccta atagggatgg aacgagggca gcaaatgggc 2820 gtgcgtgagc ggccgggctg agctgggtgg atggtggatg gggaggcagc tccgcggggg 2880 acgggcccct accgcactgt tccagcccag tctggctcaa gcgcctcgct tcttccctgg 2940 gggaccgcgt ggggaggcgg gaataatcga tgtgctgagt tcctactaag tgccttgcac 3000 ttccctggta gtttctcttg aattatttaa tccttataag gtcctagcaa ggtgaattta 3060 gttattccca cttcgcagtt gaggaaacag aaccttctag actttcaggc ccgagaccag 3120 gctcccccag tgagtcagtg gtggcgtctt tgttggaacc caggatgctt ggcctgggat 3180 gttctctttc ctacatatgc caggctccct cccgccccct accttctaga tcatggaagg 3240 agtcgtggct ctgagagatt aaatcgtgcc ctatgccttt ggccccacac atttagatct 3300 gagccccttc tccacacgca gaggccctgc cccctctcaa gtctctatgc tacattatct 3360 tgggtaatta gctcctttcc tcccaactcc tcccctatcc aaagggagtg aggggtatgt 3420 gccagtgcct cccctgggtt tgcatcgacc tcaaaaggcc ctccaggtgt ttgaaaatct 3480 ctcccatccc atggcggtga ccacggcccc attcacttaa gagctctttg ctgaagctgt 3540 tggaatggcc agggctgatt atactgaaac attcgtatgg tttcaaatac tttcaactgt 3600 ttcgctgttt ctctcttttc tctaattaaa aaaaatgaaa attcttaaaa gtcaattcat 3660 ctaaggatcc ttccacctta gttccttgta agccttgaaa tggccaaaac aaaaagatta 3720 caagcgttct taaaaatgag atgaaatcat tctgtcaaat gtgaaatgac taagtgtaac 3780 acatacaaat ttcagggaaa tttatctgtc atccctataa attaatcctt ttggatctga 3840 ttttggagca attagcctga atgttagtca cccctcccta cttggctaaa ctctcccctc 3900 ctgcctgggg tctccttaag atgagatgct tctttgataa ctaacattta tt 3952 <210> 26 <211> 2820 <212> DNA <213> Homo Sapiens <400> 26 cctaggggac aatacccagg catgttaacg gagtttaaaa tgccaaggaa attacaccac 60 aattctgccc agtatactac aggctgtcaa accgaaatgc tatgccagct aggagtgcag 120 caactcccat cctctggccc tatttaatta ggaagcttca gcagagcgaa gcctgccaag 180 cgttcgccgt cagaatctga aggaacccga gcgagcaaga agagtgcctg acccactcca 240 cagaagcctg tccagaaatg gaggagtcag cgcccactga agtcggttcc gccctcggct 300 cgcctacatg gagcctgacc agcctcagtc atgcccactc cggcctggga gacccgcaaa 360 gtgttctttt tctcaactcc cctgtactac cttgaagctt agggaagcaa agagaggggc 420 atatctggac tgcaaaacca atgtcttttg ccgcctagga gagaagggaa tgagagagag 480 agagagatag atagatagag agagagagag agagagagag agagagagag agagagagag 540 agaaattcta ttgaaaccca gctcctctag aatctgtgtg acctggtctt caacgggaga 600 ccagtgcgac ctcatggcac ctttgccagg aatcagcgat tcccctgcag tcaccatttg 660 atttattgct ttctcgctca ttctttctca taaagttatt tcttcctcat cctagtaaga 720 cttttttctt taatgatgac aaagcttctg tttcagtgtt tcccctagga ttggtgctct 780 ttcaaaacag tgaacccaga aaaccatccc gtttaatatt tctcaaaatc ctcgcagctc 840 caatgtaagc gcaagcatgc aaaggtttcc tgctacacct gcactttctg cccatcccag 900 aaccacccct cacccccggg cctgcaacag ttccccttgt ttctctggat agaggtgggt 960 ggtattaggg gtctagggca gtaggaggtg aggggctgag gaggccgcta gggtaggctg 1020 gtctgtgctg gatacgcgtg ttcttctgcg gagttaaagg gtcggggacg ggggttctgg 1080 acttaccaga gcaattccag ccggtgggcg tttggcagtc acttaaggag gtagggaaag 1140 cagcgagctt caccgggcgg gctacgatga gtagcatgac gggcagcagc agcagccagc 1200 aaaagccctc gcaaagtgtc cagctgctgc actgccgcgg ggactcccac agcaccatga 1260 ctagttcgtg caactctgca gcagcaaacg gcttccgagg aacacaggat cgcgggggcc 1320 gggcagcggg ctactgagca tcccgcggac ggcggcagca gaggcggcgg cggtggcagt 1380 ggcacccggc ggggaagcag cagccaaacc cgcgcatgat ctcgagagtt tcagcaacat 1440 ccagggactg ggctcagccc cggagcgaga gggtcgtccg ctgagaagct gcgccggaga 1500 cgcgggaagc tgctgccata aggagggagc tctgggaagc cggaggacag gaggagacgg 1560 gagtccaggg gcagacgagt ggagcccgag gaggcagggt ggagggagag tcaaggcgcc 1620 ccgcagcccg gcagccgcct ctcgagctct gccgcccgca tccctctggc gtttgggaag 1680 cagcaggtcc tcagcccgcc cggggtcacg tgggaagagg cagtcgggct ctgattggtg 1740 gagcaggatg caggtcccgg gagggagggg tcgacgagga ggtgcaagga tgcaaggagg 1800 aggcggccgc ggaagccaca gatgggctcg ctcgccaggc gctggcccga gtggggctag 1860 gcggggatgg ctcaaatgag aagctcgggc ttcagggtgg gctacccgca cactcatata 1920 ccattcgcct cactctccgc tccaggacgc cccctaccga aggcggggtc cggactagcg 1980 cccctcttcc gcgcgtgacc ccgggccgcg agtgcgggcc gcggctgggt ggcgtctctc 2040 cgagctggag atggtggggg cggaggtgtc agaggagcag cagcagcagg gcagagaggg 2100 gcgagtcggc gcgggagagg gcgtcctgct ggcgaccggc gctccagcgt gcgggagcgc 2160 gccgcctagg ctgtaggggg atgcaggctg ggaatgtcgc ggcggagagg ccagggacgt 2220 ttctctaggg atttacagga aagagggtga gaggcgatgg tgttagaacc gctcttgccg 2280 acctggaagc aacagcagca tctcccacaa gagcgtgcaa ccccaaggct gctcgccgag 2340 gcagctcagc catcccggca ggcgctctcc ttccttctct cttctcccct ctctcctccc 2400 aggccccccg cagctccgac ccagcccaag cgttcgcagg tttgaatccc tctcctcatc 2460 acccgctcct ctccagcccg tagcctatta gtgtgtccac ctgggaggtg cggtcagatg 2520 tgtttggaag gtcagattgg tcgggacaag tggtctgaga gaaagagaaa ggctcctctg 2580 catacgccgc gggtgggttg ccgggagcat cggccgggca gcggcgtccg ggaaggggag 2640 agcgggctcc atttgttggc ccaggcagtg accctgcgtt ccttactcgg gtctttgccg 2700 gatggccggt gacctggggc gacgagagaa ggtctaactc ggcaggagtc tctggctctg 2760 cgcgtttctt tcattctctc cagcgggaag ggcaaacggc atagcgggac ccgccttccg 2820 <210> 27 <211> 3104 <212> DNA <213> Homo Sapiens <400> 27 gcgggcgctg tcgagcacgg ggaggtgctg aaatagtcct ggcgtgctga ttcaagcttt 60 gattggcaga gccacccggt gactgacagg gggtctccat ggcgcccgcg ccgccaatcc 120 gcccacccca atagcggagc cagctcgcct gccggcgtgc ctgagccgag ccgagcccga 180 accccaagcc gcggagccag cacctcctcc agtcggggtc gtccgctccc ggccgttgag 240 ccaccgccgc cacccggtag tgtgtcccgc tgccccaatc cgcctcatca acaagcgcct 300 ggcacactca gccaggcccg cgggcatctg ctgcgtgtcc cgctccgggc tcagtgccct 360 cgccgccgcc ggcactgcct cgatgttcca gctgcccatc ttgaatttca gcccccagca 420 agtggccggg gtatgtgaga ccctggaaga gagcggcgat gtggagcgcc tgggtcgctt 480 cctctggtcg ctgcccgtgg cccctgcggc ctgcgaggcc ctcaacaaga atgagtcggt 540 gctacgcgca cgagccatcg tggcctttca cggtggcaac taccgcgagc tctatcatat 600 cctggaaaac cacaagttca ccaaggagtc gcacgccaag ctgcaggcgc tgtggcttga 660 agcacactac caggaggctg agaagctgcg tggaagaccc ctgggacctg tggacaagta 720 ccgagtaagg aagaagttcc cgctgccgcg caccatttgg gacggcgaac agaagacaca 780 ctgcttcaag gagcgcacgc ggcacctgct acgcgagtgg tacctgcagg atccataccc 840 taaccccagc aaaaaacgtg agctcgccca ggcaaccgga ctgaccccta cgcaggtggg 900 caactggttc aaaaaccgcc gacaaaggga ccgagcggct gcagccaaga acaggtcggt 960 acctagaggc ctccgcgctt tgagcgcacc ggggaggagg cgggtggagg cacctctggc 1020 gcccttaccc agtccctggc gactccaatt cagcaggagt tgggagcgcg gtctgtcttg 1080 ggttaagagc cctgcgttct gggctcctgg ccgggagttc ccttgccggc tctgcttccc 1140 cacccgctgg ctccccacgc ctgcgggcag ctgcagcagc tggtcccggt caccaaacca 1200 aggcttcact gggacggaga ggggaagaga aataaaaaat taaaatccta caaacagtta 1260 gggaccccaa gacccaaagc taattcttgt cagcctgggc acaggctcct actattaatc 1320 gaagcctggc ttattagcaa tgtgtcggtt tcatgttaat tatcattttc aaagcccagg 1380 tatatccctc cctaatgctt tgaaaacagt tttcaatgga cttttgagaa atgggaagtc 1440 gagttttcct cttcccatgc gctgcctgcc actcttgtct caaaacagca aactagtccg 1500 tgggccgagg cttttcgttt cccggagtgt ggatctcgat tagccaaaca ttttgcggaa 1560 gagcccggcc tcatccccca ggcccaaatg ctccttacaa tcctttttgc ctttaggtcg 1620 ggccgacccg atccaacgcg atcgcgggag cacttgctca ggcgtaagcc ccaggcagac 1680 gcaccgttag aaatggtatc ccatgtccct gggaccgatc tgtccttgtc acccacactt 1740 cgtttatttc ctgacagtcc tgtaaatctc ccaaaagtgc acaacaaaca gggaggacac 1800 tgcaagccca gtatataaaa gacctgggag ctgcggcgct gagaaagggc gcgaatcatg 1860 gtggggcaca acagtaggga cccgcggagg ggcggccgcg gactcctgcc cgacctctgt 1920 cgccttgccg agtaatcctc gccttaactg ctggggtctt cggaagaacc tctagccgcc 1980 gggctggagg gacgcaggag gtggtggggg cgggcgacgg gcggctgtgt tacgagctgt 2040 gacccgtgtt ccctttcttc cccgtagact ccagcagcag gtcctgtcac agggttccgg 2100 gcgggcacta cgggcggagg gcgacggcac gccagaggtg ctgggcgtcg ccaccagccc 2160 ggccgccagt ctatccagca aggcggccac ttcagccatc tccatcacgt ccagcgacag 2220 cgagtgcgac atctgagttg cccatccagg atgctcagaa gcagattcca gtgtaaaaac 2280 gagaaaaaca aaatgaaaga ggggaagaag atgagagacc tgcaaatcca gcgccacaga 2340 agccaggtga ccagggaccc gcgggctcgg gttgccgttt cccgccccac cccgcggccg 2400 gcctggcttc actggcgccc tttggccgcg accacgggaa ccagcgtgag gcctgaccca 2460 gcaccacgtt cttcttgctt tgctttttcc taaggatttt gctgcaaagt ctcttcggaa 2520 cccgaactgc aagctgagcg cctgcccaga ttctcccatg ggtatttcac gtcgaaagga 2580 cgctgttaca tatgtataac tttcgcttta aagttttttt ttaacaaaac atatatatgc 2640 tgtttattta cttatttaag agaccgccat ggtaggtttc tctgtagctt ggggaacttg 2700 ctgtttctaa acatgcaggc tggtggtgat gggttctgtg tggagaagcc aaacaataaa 2760 acaacctagt gggcaacctt cttaattaag ggagctgctc tcagattcct tttcttctta 2820 ttattattaa tatcattccc ttcaccaggc atgcagggac ccttgagcaa atggtctccg 2880 gaaggtctta cctatatatc ttttgccttc tttggtgctt cctggtatat gttttaaaca 2940 acctatggta ggtctataac cacctcccac gtcaaattac acgtatgtgc atatatgtat 3000 gtacctatac aaacatatgt atgtacctat acaaacatat gtatgtatgc atacacgtga 3060 tatatttaag gctagaaatt ggcaacatgt gagcgtcctc tcta 3104 <210> 28 <211> 2378 <212> DNA <213> Homo Sapiens <400> 28 atcctgagat tttagctgac tttttctgtt ctgtaatcag aggggactgt gatttgggcc 60 aatttcttcc tcatgggctt cagtggagtc agctgtggaa tggaacatca attcccaccc 120 cataggcatg ttgtgaggtt tcgctaagaa acagccataa aagggcctta agagttatga 180 tgattgtttt aaccatttag tagggagggg gcatccagcg gtgttgctcc cacgtaccga 240 tgtcacgtgg ggcggggagg cggggcggag aacggagagc gtcctctcat tctccacccc 300 cttcctccaa gtccagcgca gggggaggtg gctgcgactg actgaggggc tagggaaggc 360 tggccagggg cgtgggcgtg gctggggacg gcttgggggt ggggctgcgc aggaggctgg 420 aggagccccg cgggacccag aggcggggcg tcggcccggg gaccactgct cctccggggc 480 gtggctgcag gaggctggag gagccccgcg ggacccagag gcggggcgtc ggccggggac 540 cgctgctcct ccggggcgtg gctgctgccg agcatctccc agctcagccg agcccgtgcc 600 caggccacgc tttgttccag ccgccgcctc ctctacccta cggcgtccgg agccatccct 660 cgcctgctcg ctctctcctt tcgcccactc cctgcatctg ggcctgcatc acctttgcca 720 accgctcccc cgatcctgcc gacactcctc ccccaaactt ctgaccggca cccttgcctg 780 gtacccttct ctccattcct ccccctccat cttctttccc cgacccctct cgggtccctc 840 ttttcccaaa acccgggtct ctccgcgtgg ccccgcctcc aggccgggga tgtcccccgc 900 ggccccgcgc ccatggtcct gacgctgctt ctctccgcct acaagctgtg tcgcttcttc 960 gccatgtcgg gcccacggcg gggcgccgag cggctggcgg tgcctgggcc agatgggggc 1020 ggtggcacgg gcccatggtg ggctgcgggt ggcccgggcc cgcgaaagtg tcgccggggg 1080 caggcaccga ggtgcaggac gccctggagc gcgcgctgcc ggagctgcag caggccttgt 1140 ccgcgctgaa gcaggcgggc ggcgcgcggg ccgtgggcgc cggcctggcc gaggtcttcc 1200 aactggtgga ggaggcctgg ctgctgcggc cgtgggccgc gaggtagccc agggtctgtg 1260 cgacgccatc cgcctcgatg gcggcctcga cctgctgttg cggctgctgc aggcgccgga 1320 gttggagacg cgtgtgcagg ccgcgcgcct gctggagcag atcctggtgg ctgagaaccg 1380 gtgagcgcgc caggccgggg ttgggagagc gccgcgtggt gtggacagtt aagcgcctgc 1440 gttcccgtgt gccttgcgcc gtgcctttgc ctccctcacc tctctgactg cctgcactac 1500 atctctgtta ggggtcagcc tgtctgtttc acagataagg aaactgagcc ttgggaaagt 1560 ttagtgactt gctcagtgga tcacagtgaa ctaagatttg ctcccagggc tagtggggtg 1620 aggaatggag ttacaggaca ggagtccgtc cctggctcta tggatggaga tggcatccta 1680 ttgccaattc tccctctccc ccgcccccca agcccacagc tctccttccc accggcttgg 1740 gttcccgtct atgacacctt ctctcgccat catcccatcc ctctcccaat gagagaagaa 1800 gggaaacaca acgctcagaa aagagggagg gagacctctc ctttccctcc tccccaggct 1860 gtaaggcgtg ctggcctgag gctgcttact cccttcttgc cgccccaatc caacttctgc 1920 tccatccttc attctggttc ttgcaacagg ccagacatga tctcattctg cagctgctga 1980 tgggaaacag ttttctgctg ggaggcatgg gtgggggaag aggacaccgg ggtgcagagc 2040 ccggcgggga ccaggcagag tgtgtgttct ctcccttcac cccacttagc accaagatgc 2100 cgcaagaggg tcaaacagag gcctggttgc cactcttgca tgtctcttgg gatctctcct 2160 ggagtatgaa gacctccaag gactcacttt ccctcccttc tgatgccaga gcagaccaag 2220 ctgtcacact ccagtctcat gctgaagtct ccagcttctc aagcttagaa gagtttttgg 2280 aagagtcact ttcagctcat gcagctctca caagtgtgaa gggagtgggt tgggggtgtt 2340 ttccttgcca ttttcgaaaa gaaaaaaatt acctggtg 2378 <210> 29 <211> 2436 <212> DNA <213> Homo Sapiens <400> 29 agttctggat gacaaggact aattgcccag ggcgttggcc gagaggaata ggaagagcgc 60 cccgtggagc agggcgggcg agaagagccg ggcggccgcg gggtcctcgc gcatgctggg 120 caggaagagg aagagctgca gcacgaaggt caccagggag atgcacaaga agtaggcggg 180 ggccaccacg ttgagcagcc gcagggccag catcctcgat tacattcctg cggggcccgg 240 ggtgagaaga ggactgactg actacggcgt ccagggggcg ccctcgcccg ctcctccgtg 300 ccgcgcgtct ggggcactgc acgcgactcc acgcccccaa ccccctgtcc cgcggatttc 360 ccctccccag ttccctaacc ccggatcagg caggccagag acccgagccc gcagcggcct 420 cgggtctagg ccccacctgg gggtgagtgt tgcctggggt tttgagcgag ctcggcgcct 480 tggcgcggca gagtctggca caggagggag ggactcgttt gcagtcttta ggagttgtga 540 gggtgggggg caccggggga taggactcct cccctctgtg gatgtggaaa caagcccagg 600 tttgggattt ctggttcaga cctccctagg aggagaaagg gaaggatttg gggtcggggg 660 caggagaatc agcggcactt gacctgctgg aaatcctgct tcacactccc ctttctccgt 720 ccctgcgtcc ccacccacac acacatcttg ggcagcactc agggacctca ccaggttacc 780 caaggctctt tggaggtatg tgtgcgtgag ggaccacgat gtgtgtgtgt gtgtccttgt 840 ctgtgactct gtacgtgtaa tctgtgtgcg cttgagtatc tgtatttgtg tatgtatata 900 tctgcgtgta cagacacgca gcctctgcta tctagcttta aaaaaatcaa ttgaaacaat 960 cgatacactc acactcgctc tcgggcaccg ggtgaggtgg gggcgcaacc agaatacctg 1020 tgtcagcggg tcctggccag cacatctctc caacgctggc tgcccgggct atttctttgc 1080 gaagagcgtt ttcatttgag gcgaaattaa aatcccccct tcgcgcccgc ctcccgccct 1140 cctgctgaga gaaacccaaa caaccctcat ggcgccgaaa tcctttccat gccgacaagc 1200 ccgccctggg cgcacgagtg gatgcttggc cagcctttcc tgggatcgac cccgccgccg 1260 tgctcagccc tcaccacgtc cccatcccac cccacgcctc acagccgggg ttcctggcca 1320 gcttcggaag ccaccgagaa ataggattcc gtgcgcccga gagaactttt ccaggggcta 1380 aggaatcggc cagccggagg cgcgagaaaa gttctgggaa ggcggttgca cctaggatgg 1440 gtggatgcca cggggcctcc gtccaggctg tcccgtccgc acgggtcgac tggtcacctt 1500 ggaatcccct ttgcaggtcc cagcgccccc cgggaacccg cagcctccgc ggagagcgtg 1560 ggcctctccc taccgctggg gcgcagcgca gtgcacgcct gagggtggtc gccgggggct 1620 gggcacgccc ccagtcctgc gccgccgggg gctgcggcgg tgctgcccac cccagagagc 1680 cctcggcctg gggctccggc gaagcaagtg ccttcccggc gccggtcgcc aggggggcgc 1740 gggagcagcc agatgcgccg cagcgctggg aaggcggcga aggacagggg ctaggggagt 1800 gaggggcgct cggcaggcag cctcagccct ggccctgcgc gggagaaggg acagcagaga 1860 ccgcccgtgg ggccccgggg tgtagggagc tgtccgttca gccctggcgc ccgcctcgcc 1920 cgcggcagag ggcggcacag ccggagcctt ggaaagaccg gcagcgccgg cagccgcggg 1980 cttctcggcc actgcctccc ggacgcacgg gaagccgccc cccgcgccgc cgccgccgca 2040 ctgccgccgt cgcagagggg tgaggaaatc aactcaccga gctctggtcg ccgacaagag 2100 gagccccgga cgccggctct cgccctgccc gaggctgcaa agttgtggac tcggcccggc 2160 tggctcgcag cctgcgcttc gcttcgggaa ctgggcaagt agcggggatg tggggaggag 2220 ggagcgggca gctgctggct tcccacttgg gcgccagcga gtaagggcca ggaagcggcg 2280 gggatggcag ctgggcaccc cccagccccg ccacccctcc ctccgctcct gggggcggtg 2340 ctctggccgc cagtctcagc atcgtggact tgccccctcc tcccctctcg attccccttg 2400 agcgggctgg ggcgccctgc ctggtttcag cgcccg 2436 <210> 30 <211> 2804 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 30 ttaaggttcg tcggatttga ggtcgtttgg ggcgttaaat agatttattt atgagtatat 60 tcggttaata tatttaagtt taatagtggg cgggattttt ggttggtttc gatttttttt 120 atagtgtgtg taaacgggta tttattagat tttttttgtt tgttttttta tttgtaaatt 180 ttgaaaggag agtatttttc ggggtgattt tgaaaattat gttagaattg aaaaggtttg 240 tgtaaatgcg aggtgtaatg atgatttatt agaagtagtt agttttgtac gtgtttgtag 300 gatagatgtt agaacgtttt ataaatgtgt gtatatatat attacgtatg tgtgaaggtg 360 tatatttgtt tttagatatt tgataaatgt atatacgtat gcgtgtattt ttggttgaga 420 gtaaaggggt taatataggg tttatatagg atattatttt gtagttttgt gcgtgtatag 480 tatatacgcg agtacgattg tttgtgtttg gagatatcgt atggtatcgg aggagttgtt 540 tagtcgtcgg tgttatttgg gaagtagggt ttcgggtgtt gttttggagc gcgggaaagt 600 tcggattcgg gtttgttggt tagcgtttcg gcgtcgtcgg gtttttttat tttttattcg 660 tcggtcggtg agcggtttta gttttaagat tttcgatttt gtcggtgagg ggagggagcg 720 agaaggagtg cgtttcgggt ttaagaggtt gtagggtttt attttttagg tttgtcgttt 780 tttttttatt tttttaggtt atatttttat ttaaaataaa gaagggtgtt tgatttattt 840 aggttaggga agtcggtttt cgggagtttt ttgtttttat aagttatggt gaagggaggc 900 gaagttaggg tttgttacgg tttgggagaa aatgcggttg tagggttttt ttgggttgta 960 gcgttggttc ggggttttaa gattgttaag gtgtgtgtgg gaggcgcgta gtgtggttat 1020 cgaagagttt tttattatcg tatcggtagg tcgtcgggtt cgtttttttt ttatgttttt 1080 aagggttttg agttgcgtag tattcgtatt atttagaagt gtttgtggag aaaacgattt 1140 taggtgtaag tttaaggttg ttgtttgtaa aggtaatgtc gtggagattg ggttttatag 1200 cgatttgggt ttttaagtta tcgaaagtta tagggtaggg ttataaatat tttttcgttt 1260 tttttgtaga atcgtgcggt tgataggaga gcgttgcgta gaaaattcga ggtcgggcgt 1320 tggaggagtt ttcgcggttc ggagaaggta tagaggcgtt tttgagaggc gtagttggaa 1380 taggcgatgt acgggttcgg atttggtcgg ttaatcgagt ttagcggtcg cgaaaattag 1440 agtcgttata gaggttgagt acgattttat ttttggggat cgggttcggt ggggagttat 1500 tgtttttaac gtttttagag attttaagta ggataatata atgttggtag gagtaaggtg 1560 taaggaattt agcggtagaa gtttttcggg ggggtgggga aaggtagatt cgtgtttcgt 1620 ttgagtttgg gggtggggat agtttttggt tttgtagttt ttgtttcggg gattagttgg 1680 gtttatttaa tttttttata tggggttgaa aggggttaat gggacggttt cgtcgttttt 1740 ttttcgggat tttatagggt tttgattcgg tttttatttt tgtacggtta gtagtcgcgg 1800 gggttttagg aaggaggata aaggttcggt gttatcgcgg gcgggggttc ggttttttgg 1860 ttttttgttt atatttatag tttttagcgg ttgttggggg aagattttta aaaatatgtg 1920 tcgaattttt tttttttttt ttttagaaat aaataaataa aaaaggtaaa aggcgaattt 1980 ttttttattt ttcgtttata gagattaaag ttttttggga ttttgttttt tttttttttt 2040 tgattgttta gaaatatttg tttttttttg tatatagagg aaaatgcggg gaaaggtttt 2100 ttaaaattcg gttttatatt attattatta ttaaggataa tcgggtaggt tgaggtttta 2160 acgtggatga ttcgagttgg tttcgcgtcg gggttttgta gttattgttt tgtgcgttta 2220 gtatttttgg gggcgattag ggtttttgcg ttttcgttcg tcgttcggta gtcgagagta 2280 ttttgtgttt agattggtcg atttattttt tttcgaattt tgtttagagt tggtaagggg 2340 gatttagttc gcgttttaag atttgggttt gtagcgtcgt taataggttc ggggatacga 2400 ggcgttttag gtcggggttt tttcggttgt tggttttttt cgttttttat tcgttggcgg 2460 cgtttcggtc gttcgtaatt gatttaattc gttttttgcg tttgtttttt aggtttttcg 2520 tttttttata aaggtttagg ggagtttcgt ttataggttg attttgtaat ttttggttcg 2580 gtggttattt tttgtttttt tgaaaaagaa aaggaaaaaa aaaaaaaaaa agaaaaaatt 2640 aattagtcga gggaggcgcg tgaggattgg aggcgttagt cggatagttt atgagtaggt 2700 ttttgggtcg gtgtcgtttc gcgggttagt acggtttttt ttagagaaaa ttttttaaac 2760 gtgtgaagat cgttttgggg gaagcgagag ggaggttgga ggag 2804 <210> 31 <211> 2804 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 31 tttttttaat ttttttttcg ttttttttaa agcggttttt atacgtttag gaggtttttt 60 ttgagaaagg tcgtgttgat tcgcgaagcg gtatcgattt agggatttat ttataggttg 120 ttcggttggc gtttttagtt tttacgcgtt tttttcgatt ggttgatttt tttttttttt 180 tttttttttt tttttttttt tttagaaaag tagaaggtag ttatcgggtt agaggttgta 240 gggttagttt gtgggcgagg tttttttagg tttttgtgga gaaacgggaa atttgagggg 300 taaacgtagg aagcgggttg ggttaattgc gggcgatcga ggcgtcgtta gcgggtgggg 360 agcgagaggg gttagtagtc gggaagattt cggtttggag cgtttcgtgt tttcgggttt 420 gttggcggcg ttgtaagttt aggttttggg gcgcgagtta agtttttttt gttagtttta 480 aataaaattc gggggagaat gagtcggtta gtttgggtat agggtgtttt cgattgtcgg 540 gcggcgggcg gaagcgtagg ggttttgatc gtttttagag gtgttgagcg tatagggtag 600 tggttgtaga gtttcggcgc gaggttaatt cggattattt acgttgggat tttagtttgt 660 tcggttgttt ttagtaataa taatagtatg aaatcgagtt ttaaaaaatt ttttttcgta 720 ttttttttta tgtataaggg agaataagta tttttaggta gttaaagaaa aaaaaagggt 780 aggattttag gaaattttaa tttttatgga cgaggagtga aggggaattc gttttttgtt 840 ttttttgttt gtttgttttt agaagagaaa aaaaggaaat tcgatatata tttttaaaaa 900 ttttttttta ataatcgtta aaggttgtga gtgtgagtag agagttagga aatcgagttt 960 tcgttcgcgg tgatatcggg tttttgtttt tttttttgaa gttttcgcga ttgttgatcg 1020 tgtagagata aaggtcgggt tagggttttg tggaatttcg agggaggggc ggcggggtcg 1080 ttttattggt tttttttaat tttatgtagg ggggttaggt gggtttagtt gattttcgga 1140 ataggggtta taaggttagg ggttgttttt atttttaggt ttagacgagg tacggatttg 1200 ttttttttta ttttttcgaa aggtttttgt cgttaaattt tttgtatttt gtttttatta 1260 gtattatatt gttttattta aagtttttgg aggcgttagg gatagtggtt ttttatcgga 1320 ttcgattttt agaaatggaa tcgtgtttaa tttttgtggc gattttggtt ttcgcgatcg 1380 ttgggttcgg ttggtcggtt agattcgaat tcgtgtatcg tttgttttag ttgcgttttt 1440 taggggcgtt tttgtgtttt tttcgggtcg cggagatttt tttagcgttc ggtttcgaat 1500 tttttgcgta acgttttttt gttagtcgta cggttttgta gagaaggcgg gagagtgttt 1560 gtgattttgt tttgtagttt tcggtgattt aaaaatttag gtcgttgtgg aatttagttt 1620 ttacggtatt gtttttgtag gtagtagttt tgggtttata tttgaggtcg ttttttttat 1680 agatattttt gggtgatgcg agtgttgcgt agtttagaat ttttggaagt atgagaggag 1740 gacgagttcg gcggtttgtc ggtgcggtga tggagggttt ttcggtagtt atattgcgcg 1800 ttttttatat atattttaat agttttgggg tttcgggtta gcgttgtagt ttaaagagat 1860 tttgtagtcg tatttttttt taggtcgtgg taaattttgg tttcgttttt ttttattatg 1920 gtttgtgagg gtaggaggtt ttcgggggtc gatttttttg atttgaatga gttaggtatt 1980 tttttttatt ttaagtgggg gtgtgatttg aggagataaa ggaaggacga tagatttggg 2040 gagtggggtt ttgtagtttt ttgggttcgg agcgtatttt ttttcgtttt ttttttttat 2100 cggtaggatc gggggttttg aaattggagt cgtttatcgg tcggcggatg agagataaag 2160 gagttcggcg gcgtcgaagc gttgattagt agattcggat tcggattttt tcgcgtttta 2220 gagtagtatt cgaaatttta ttttttaggt ggtatcgacg gttgagtagt tttttcggtg 2280 ttatacggtg tttttaggta tagatagtcg tgttcgcgtg tgtattgtgt acgtataaga 2340 ttgtaggatg atgttttgta tgagttttgt attagttttt ttgtttttag ttagaggtat 2400 acgtatacgt gtgtgtattt gttaagtgtt tagggatagg tgtgtatttt tatatatacg 2460 tgatgtgtat gtgtatatat ttgtagaacg ttttagtatt tattttatag gtacgtatag 2520 ggttggttgt ttttaataag ttattattat atttcgtatt tatataggtt tttttagttt 2580 tggtatgatt tttagaatta tttcgggaaa tatttttttt ttaaagttta tagatgagga 2640 aataagtaaa aagaatttaa tgggtattcg tttgtatata ttgtgagaga gatcgaggtt 2700 agttaaagat ttcgtttatt gttgaatttg ggtgtgttgg tcgaatgtgt ttatagatgg 2760 gtttgtttag cgttttaggc gattttaggt tcggcgggtt ttgg 2804 <210> 32 <211> 3952 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 32 ggtcgtagtc ggagaggaat aggaatcgta gtggggacgt tttggttttc gggtttatag 60 tattcgggac ggacgcgtag tagcgcgggt cgggaattgg gtattagggc gggatgggtg 120 agaggtttta agggataagg tagggagaag cgtagcgggg tgcggggaat cgtacgtttt 180 ttttttgttt ttgtttttta tttcgaggcg gtagggcggg cgggcgcggt ttcgggggtg 240 ggcgggttgg gcggggcgga ggcggggtcg tagtattggt tttatttagt ttttttcgtt 300 cgtagttaga gcgagtcgag tcgcggttag tttcggcggg tagggggggc gttggagcgt 360 agcgtagcgt agttttatta gttcgtaaag cggatcgagt tggaagtcga gcgttgtcgc 420 gggaggcggg cgatgggggt aggtgttatc ggtcgcgtta tggacgggtc gcgtttgttg 480 ttgttgttgt ttttgggggt gagtgttagt cggagggggt tcgttttttt tttcgggatt 540 agaatttcga gaagagtcgg gcgtcgttat taaggaaata gaatagagta ttggggtttt 600 agatattgag ggtgggtggt gggaaaggat ttttgatgtc gggattacga aggagggttt 660 agggttttcg gagcgtagag gcgatttttt agggtggaga tgagggtaag atcggagtac 720 ggatgtcggt ttttaggtat cgtagggggc ggtgggggag ttgggagggg ttttttaaga 780 gggggtatgg ggtttttcga tgtttaggtt tttcggaaga ggatattcga atgtcgggat 840 ttcgaaggga tttttttttt agtatttcgg tttttggaga gtcgtgggat agaattaagg 900 cgagagaagg agggggaatt ggacggggat tagagatgag aggggcgagt tgggttgggg 960 cggggagttc gggacgacgg gatggaataa tggaggaggt cggagggatt ggaggtagag 1020 gggattcggt aaggataatg gggatcggtt agataatggg ggggaggggc gtcggaggga 1080 gaggttgggg agcgggagag aggttgagaa gtgggttagg gagggtagaa gaggggcgac 1140 ggcgagggcg gtagagagat ggaagtagaa ggaaaggaga tagagcgggg cgcggatttt 1200 gaagtggtcg gggtttcgtt tgttcgttga gggatagtga gacgagaaga gagagtagag 1260 gtttggatat ttttagcgtt tgttttcgcg tttttgttcg cggttttttt tagtttcgga 1320 attggggttg cggatttaag gttgggaggg gagtgtttat ttcgtcgggg cgaattcgtt 1380 ttcggggttt ttttacggtc ggcgggtttt ttcgacgcgc gtgtttttac ggtttgaagt 1440 agcgtagcgg atcgcgaggg acggagcggg tgtgttttta ttcgggttgg cggtggttac 1500 gtttcggggt gtagagcgtc ggggcgtatt aggcggggat tttttttggt cgcgcgtagt 1560 tttggttacg taggcgggag gcggtaggta gggggcgttg cggggcgagg taagtgtagt 1620 tcgtcgttgt ttgtttgcga gtttggggtt gcgcgtcgtt ttttatttag ttgcgcgatt 1680 cgagcgtcgc gtttatcgcg tttcgtgggt tttcgcgttt cgaagggtcg ggattcggtt 1740 tgagtttttt ttggttttcg gtgtaagtcg ttgggtattt aacgagacgg gggcgttcgg 1800 acgtttcgga ttttgtagcg cggtatttcg ggttatcgat tcggtaaagg tcggcgggtt 1860 tttcgggtgg ttcgacgaga ttgttagatg tggtttgttt tatggttatg aatcgaatgt 1920 tttggaaggt ttggtaacgg aggaggcgtt tttatttttt tcgttagtat tttttattag 1980 agtattgcgt tttaaatttc ggttttatag atacggagat tgaggttttg agagtttaaa 2040 cgatttggtt aagattttat agtaagttgg gttagagtcg tggttagatt tttcgatttg 2100 atttttagtt cggtattttt ttattttttt agggggtagt cgttgtttta gttcggggtt 2160 acggttgcgt tttttagtag ggcggggggg gttgatattg tttttagagt tcgtcggcgg 2220 tagagtttgc gggtgaggtg ggtagagatt ttgttcgggt gcgggtttta gttcgaaagt 2280 ttagttttag ttttttggag ttgttaggat ttgtggttgc gttcggggat ttgggagcga 2340 tcgcgggtac gtttgttgat taacgtcgtt ggttagagac gttgtttaga cgcgggtggg 2400 cgagcgtaga ttaggagagc ggggaggagg gatcggattt tagaggggta acgatttggg 2460 tttcgggttt gggtaagagc gagggttttc gcgcgaagat ttaaggaagg aggggagttg 2520 ggcgtggagg atttgggcgt ttgggaaggt gtatttcgat aggaatttgt cgtttgtagt 2580 ttttgcggtt ttcgttttcg tttcggcgcg cggttgttcg gtttgggatg gttgtgcgcg 2640 gttcgagttt ttttttgggt cgcggtgaga gagagagggt tgaaattaga gcgcgtttcg 2700 gcgggtcggt tggcgggtcg cgtcggtaat ggaggtattt tgttatttag acgtttgtaa 2760 ttagagtcgt cgggttggtt aatgcgttta atagggatgg aacgagggta gtaaatgggc 2820 gtgcgtgagc ggtcgggttg agttgggtgg atggtggatg gggaggtagt ttcgcggggg 2880 acgggttttt atcgtattgt tttagtttag tttggtttaa gcgtttcgtt ttttttttgg 2940 gggatcgcgt ggggaggcgg gaataatcga tgtgttgagt ttttattaag tgttttgtat 3000 ttttttggta gttttttttg aattatttaa tttttataag gttttagtaa ggtgaattta 3060 gttattttta tttcgtagtt gaggaaatag aattttttag atttttaggt tcgagattag 3120 gtttttttag tgagttagtg gtggcgtttt tgttggaatt taggatgttt ggtttgggat 3180 gttttttttt ttatatatgt taggtttttt ttcgtttttt attttttaga ttatggaagg 3240 agtcgtggtt ttgagagatt aaatcgtgtt ttatgttttt ggttttatat atttagattt 3300 gagttttttt tttatacgta gaggttttgt ttttttttaa gtttttatgt tatattattt 3360 tgggtaatta gttttttttt ttttaatttt ttttttattt aaagggagtg aggggtatgt 3420 gttagtgttt tttttgggtt tgtatcgatt ttaaaaggtt ttttaggtgt ttgaaaattt 3480 tttttatttt atggcggtga ttacggtttt atttatttaa gagttttttg ttgaagttgt 3540 tggaatggtt agggttgatt atattgaaat attcgtatgg ttttaaatat ttttaattgt 3600 ttcgttgttt tttttttttt tttaattaaa aaaaatgaaa atttttaaaa gttaatttat 3660 ttaaggattt ttttatttta gttttttgta agttttgaaa tggttaaaat aaaaagatta 3720 taagcgtttt taaaaatgag atgaaattat tttgttaaat gtgaaatgat taagtgtaat 3780 atatataaat tttagggaaa tttatttgtt atttttataa attaattttt ttggatttga 3840 ttttggagta attagtttga atgttagtta ttttttttta tttggttaaa tttttttttt 3900 ttgtttgggg tttttttaag atgagatgtt tttttgataa ttaatattta tt 3952 <210> 33 <211> 3952 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 33 aataaatgtt agttattaaa gaagtatttt attttaagga gattttaggt aggaggggag 60 agtttagtta agtagggagg ggtgattaat atttaggtta attgttttaa aattagattt 120 aaaaggatta atttataggg atgatagata aatttttttg aaatttgtat gtgttatatt 180 tagttatttt atatttgata gaatgatttt attttatttt taagaacgtt tgtaattttt 240 ttgttttggt tattttaagg tttataagga attaaggtgg aaggattttt agatgaattg 300 atttttaaga atttttattt tttttaatta gagaaaagag agaaatagcg aaatagttga 360 aagtatttga aattatacga atgttttagt ataattagtt ttggttattt taatagtttt 420 agtaaagagt ttttaagtga atggggtcgt ggttatcgtt atgggatggg agagattttt 480 aaatatttgg agggtttttt gaggtcgatg taaatttagg ggaggtattg gtatatattt 540 tttatttttt ttggataggg gaggagttgg gaggaaagga gttaattatt taagataatg 600 tagtatagag atttgagagg gggtagggtt tttgcgtgtg gagaaggggt ttagatttaa 660 atgtgtgggg ttaaaggtat agggtacgat ttaatttttt agagttacga ttttttttat 720 gatttagaag gtagggggcg ggagggagtt tggtatatgt aggaaagaga atattttagg 780 ttaagtattt tgggttttaa taaagacgtt attattgatt tattggggga gtttggtttc 840 gggtttgaaa gtttagaagg ttttgttttt ttaattgcga agtgggaata attaaattta 900 ttttgttagg attttataag gattaaataa tttaagagaa attattaggg aagtgtaagg 960 tatttagtag gaatttagta tatcgattat tttcgttttt ttacgcggtt ttttagggaa 1020 gaagcgaggc gtttgagtta gattgggttg gaatagtgcg gtaggggttc gtttttcgcg 1080 gagttgtttt tttatttatt atttatttag tttagttcgg tcgtttacgt acgtttattt 1140 gttgttttcg ttttattttt attaggcgta ttagttagtt cggcggtttt ggttatagac 1200 gtttgaatga taaagtgttt ttattatcgg cgcggttcgt tagtcgattc gtcgggacgc 1260 gttttggttt tagttttttt ttttttatcg cggtttagga agaaattcgg atcgcgtata 1320 gttattttag atcgagtagt cgcgcgtcga ggcggaggcg ggagtcgtag gggttgtaga 1380 cggtaggttt ttgtcggggt atattttttt aagcgtttag gttttttacg tttagttttt 1440 tttttttttt gggttttcgc gcggggattt tcgtttttgt ttagattcgg agtttaagtc 1500 gttgtttttt tgggattcgg tttttttttt tcgttttttt ggtttacgtt cgtttattcg 1560 cgtttgagta gcgtttttaa ttagcggcgt tagttagtag acgtgttcgc ggtcgttttt 1620 aaattttcgg acgtagttat aggttttgat agttttaggg aattggggtt gagttttcgg 1680 gttggggttc gtattcggat agaatttttg tttattttat tcgtaggttt tatcgtcgac 1740 ggattttggg gatagtgtta atttttttcg ttttgttggg aaacgtagtc gtgatttcga 1800 gttgggatag cggttgtttt ttgaaaaggt gggggagtat cgagttggga attaggtcgg 1860 ggagtttagt tacgattttg gtttaatttg ttgtgagatt ttggttaagt cgtttaaatt 1920 tttagagttt tagttttcgt atttgtaaag tcggaatttg gggcgtagtg ttttgatgaa 1980 agatgttggc ggggagagtg aagacgtttt tttcgttgtt agatttttta gggtattcgg 2040 tttatggtta taaagtaggt tatatttgat aatttcgtcg gattattcgg aggattcgtc 2100 gatttttgtc gagtcggtgg ttcgggatat cgcgttatag aattcgaggc gttcgggcgt 2160 tttcgtttcg ttaggtgttt agcggtttgt atcgagagtt aggagaggtt tagatcggat 2220 ttcgattttt cgaggcgcgg gagtttacgg agcgcggtgg gcgcggcgtt cgggtcgcgt 2280 agttaggtgg ggagcggcgc gtagttttag attcgtaggt aggtagcggc ggattgtatt 2340 tgtttcgttt cgtagcgttt tttgtttgtc gtttttcgtt tgcgtagtta gagttgcgcg 2400 cggttaggaa gggttttcgt ttagtgcgtt tcggcgtttt gtatttcgag acgtagttat 2460 cgttagttcg ggtaggggta tattcgtttc gtttttcgcg attcgttgcg ttgttttaag 2520 tcgtgagaat acgcgcgtcg gaggagttcg tcggtcgtgg gggaatttcg ggagcgggtt 2580 cgtttcggcg aagtgggtat ttttttttta gttttagatt cgtagtttta atttcgggat 2640 tgggagaggt cgcgagtagg agcgcgggga taggcgttgg aaatgtttaa gtttttgttt 2700 ttttttttcg ttttattgtt ttttagcggg taggcgggat ttcgattatt ttagggttcg 2760 cgtttcgttt tgtttttttt ttttttgttt ttattttttt gtcgttttcg tcgtcgtttt 2820 ttttttgttt tttttaattt attttttaat ttttttttcg ttttttaatt ttttttttcg 2880 acgttttttt tttttattgt ttggtcggtt tttattgttt ttgtcgggtt ttttttgttt 2940 ttagtttttt cgattttttt tattgtttta tttcgtcgtt tcgggttttt cgttttagtt 3000 tagttcgttt tttttatttt tagttttcgt ttagtttttt tttttttttt cgttttggtt 3060 ttgttttacg attttttaga gatcgagatg ttgaggggaa agttttttcg ggatttcggt 3120 attcgagtgt tttttttcga agaatttggg tatcggagag ttttatgttt ttttttgaaa 3180 gatttttttt agttttttta tcgttttttg cggtatttga ggatcggtat tcgtgtttcg 3240 gttttgtttt tatttttatt ttggagagtc gtttttgcgt ttcgggaatt ttagattttt 3300 tttcgtggtt tcggtattag aggttttttt ttattattta tttttagtat ttgggatttt 3360 aatgttttgt tttgtttttt tggtggcggc gttcggtttt tttcggagtt ttgatttcgg 3420 gaaagggagc gggttttttt cggttaatat ttatttttag aagtagtaat agtagtaggc 3480 gcggttcgtt tatggcgcgg tcggtggtat ttgtttttat cgttcgtttt tcgcggtagc 3540 gttcgatttt tagttcggtt cgttttgcgg attgatgggg ttgcgttgcg ttgcgtttta 3600 gcgttttttt tgttcgtcgg agttggtcgc ggttcggttc gttttggttg cgggcgggag 3660 aggttgggtg aagttagtgt tgcggtttcg ttttcgtttc gtttagttcg tttattttcg 3720 gaatcgcgtt cgttcgtttt gtcgtttcgg ggtgggaagt agaggtaaag ggagggcgtg 3780 cggtttttcg tatttcgttg cgtttttttt tgttttgttt tttagagttt tttatttatt 3840 tcgttttggt atttagtttt cggttcgcgt tattgcgcgt tcgtttcgga tgttgtgggt 3900 tcggggatta gggcgttttt attgcggttt ttgttttttt tcggttgcgg tt 3952 <210> 34 <211> 2820 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 34 tttaggggat aatatttagg tatgttaacg gagtttaaaa tgttaaggaa attatattat 60 aattttgttt agtatattat aggttgttaa atcgaaatgt tatgttagtt aggagtgtag 120 taatttttat tttttggttt tatttaatta ggaagtttta gtagagcgaa gtttgttaag 180 cgttcgtcgt tagaatttga aggaattcga gcgagtaaga agagtgtttg atttatttta 240 tagaagtttg tttagaaatg gaggagttag cgtttattga agtcggtttc gttttcggtt 300 cgtttatatg gagtttgatt agttttagtt atgtttattt cggtttggga gattcgtaaa 360 gtgttttttt ttttaatttt tttgtattat tttgaagttt agggaagtaa agagaggggt 420 atatttggat tgtaaaatta atgttttttg tcgtttagga gagaagggaa tgagagagag 480 agagagatag atagatagag agagagagag agagagagag agagagagag agagagagag 540 agaaatttta ttgaaattta gtttttttag aatttgtgtg atttggtttt taacgggaga 600 ttagtgcgat tttatggtat ttttgttagg aattagcgat ttttttgtag ttattatttg 660 atttattgtt ttttcgttta ttttttttta taaagttatt ttttttttat tttagtaaga 720 tttttttttt taatgatgat aaagtttttg ttttagtgtt ttttttagga ttggtgtttt 780 tttaaaatag tgaatttaga aaattatttc gtttaatatt ttttaaaatt ttcgtagttt 840 taatgtaagc gtaagtatgt aaaggttttt tgttatattt gtattttttg tttattttag 900 aattattttt tattttcggg tttgtaatag ttttttttgt ttttttggat agaggtgggt 960 ggtattaggg gtttagggta gtaggaggtg aggggttgag gaggtcgtta gggtaggttg 1020 gtttgtgttg gatacgcgtg tttttttgcg gagttaaagg gtcggggacg ggggttttgg 1080 atttattaga gtaattttag tcggtgggcg tttggtagtt atttaaggag gtagggaaag 1140 tagcgagttt tatcgggcgg gttacgatga gtagtatgac gggtagtagt agtagttagt 1200 aaaagttttc gtaaagtgtt tagttgttgt attgtcgcgg ggatttttat agtattatga 1260 ttagttcgtg taattttgta gtagtaaacg gttttcgagg aatataggat cgcgggggtc 1320 gggtagcggg ttattgagta tttcgcggac ggcggtagta gaggcggcgg cggtggtagt 1380 ggtattcggc ggggaagtag tagttaaatt cgcgtatgat ttcgagagtt ttagtaatat 1440 ttagggattg ggtttagttt cggagcgaga gggtcgttcg ttgagaagtt gcgtcggaga 1500 cgcgggaagt tgttgttata aggagggagt tttgggaagt cggaggatag gaggagacgg 1560 gagtttaggg gtagacgagt ggagttcgag gaggtagggt ggagggagag ttaaggcgtt 1620 tcgtagttcg gtagtcgttt ttcgagtttt gtcgttcgta tttttttggc gtttgggaag 1680 tagtaggttt ttagttcgtt cggggttacg tgggaagagg tagtcgggtt ttgattggtg 1740 gagtaggatg taggtttcgg gagggagggg tcgacgagga ggtgtaagga tgtaaggagg 1800 aggcggtcgc ggaagttata gatgggttcg ttcgttaggc gttggttcga gtggggttag 1860 gcggggatgg tttaaatgag aagttcgggt tttagggtgg gttattcgta tatttatata 1920 ttattcgttt tatttttcgt tttaggacgt tttttatcga aggcggggtt cggattagcg 1980 tttttttttc gcgcgtgatt tcgggtcgcg agtgcgggtc gcggttgggt ggcgtttttt 2040 cgagttggag atggtggggg cggaggtgtt agaggagtag tagtagtagg gtagagaggg 2100 gcgagtcggc gcgggagagg gcgttttgtt ggcgatcggc gttttagcgt gcgggagcgc 2160 gtcgtttagg ttgtaggggg atgtaggttg ggaatgtcgc ggcggagagg ttagggacgt 2220 ttttttaggg atttatagga aagagggtga gaggcgatgg tgttagaatc gtttttgtcg 2280 atttggaagt aatagtagta ttttttataa gagcgtgtaa ttttaaggtt gttcgtcgag 2340 gtagtttagt tatttcggta ggcgtttttt tttttttttt tttttttttt tttttttttt 2400 aggtttttcg tagtttcgat ttagtttaag cgttcgtagg tttgaatttt tttttttatt 2460 attcgttttt ttttagttcg tagtttatta gtgtgtttat ttgggaggtg cggttagatg 2520 tgtttggaag gttagattgg tcgggataag tggtttgaga gaaagagaaa ggtttttttg 2580 tatacgtcgc gggtgggttg tcgggagtat cggtcgggta gcggcgttcg ggaaggggag 2640 agcgggtttt atttgttggt ttaggtagtg attttgcgtt ttttattcgg gtttttgtcg 2700 gatggtcggt gatttggggc gacgagagaa ggtttaattc ggtaggagtt tttggttttg 2760 cgcgtttttt ttattttttt tagcgggaag ggtaaacggt atagcgggat tcgtttttcg 2820 <210> 35 <211> 2820 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 35 cggaaggcgg gtttcgttat gtcgtttgtt tttttcgttg gagagaatga aagaaacgcg 60 tagagttaga gatttttgtc gagttagatt ttttttcgtc gttttaggtt atcggttatt 120 cggtaaagat tcgagtaagg aacgtagggt tattgtttgg gttaataaat ggagttcgtt 180 tttttttttt cggacgtcgt tgttcggtcg atgttttcgg taatttattc gcggcgtatg 240 tagaggagtt tttttttttt ttttagatta tttgtttcga ttaatttgat tttttaaata 300 tatttgatcg tattttttag gtggatatat taataggtta cgggttggag aggagcgggt 360 gatgaggaga gggatttaaa tttgcgaacg tttgggttgg gtcggagttg cggggggttt 420 gggaggagag aggggagaag agagaaggaa ggagagcgtt tgtcgggatg gttgagttgt 480 ttcggcgagt agttttgggg ttgtacgttt ttgtgggaga tgttgttgtt gtttttaggt 540 cggtaagagc ggttttaata ttatcgtttt ttattttttt ttttgtaaat ttttagagaa 600 acgtttttgg ttttttcgtc gcgatatttt tagtttgtat ttttttatag tttaggcggc 660 gcgttttcgt acgttggagc gtcggtcgtt agtaggacgt tttttttcgc gtcgattcgt 720 ttttttttgt tttgttgttg ttgttttttt gatattttcg tttttattat ttttagttcg 780 gagagacgtt atttagtcgc ggttcgtatt cgcggttcgg ggttacgcgc ggaagagggg 840 cgttagttcg gatttcgttt tcggtagggg gcgttttgga gcggagagtg aggcgaatgg 900 tatatgagtg tgcgggtagt ttattttgaa gttcgagttt tttatttgag ttattttcgt 960 ttagttttat tcgggttagc gtttggcgag cgagtttatt tgtggttttc gcggtcgttt 1020 tttttttgta tttttgtatt ttttcgtcga tttttttttt tcgggatttg tattttgttt 1080 tattaattag agttcgattg ttttttttta cgtgatttcg ggcgggttga ggatttgttg 1140 ttttttaaac gttagaggga tgcgggcggt agagttcgag aggcggttgt cgggttgcgg 1200 ggcgttttga tttttttttt attttgtttt ttcgggtttt attcgtttgt ttttggattt 1260 tcgttttttt ttgtttttcg gttttttaga gttttttttt tatggtagta gtttttcgcg 1320 ttttcggcgt agttttttag cggacgattt tttcgtttcg gggttgagtt tagtttttgg 1380 atgttgttga aattttcgag attatgcgcg ggtttggttg ttgttttttc gtcgggtgtt 1440 attgttatcg tcgtcgtttt tgttgtcgtc gttcgcggga tgtttagtag ttcgttgttc 1500 ggttttcgcg attttgtgtt tttcggaagt cgtttgttgt tgtagagttg tacgaattag 1560 ttatggtgtt gtgggagttt tcgcggtagt gtagtagttg gatattttgc gagggttttt 1620 gttggttgtt gttgttgttc gttatgttat ttatcgtagt tcgttcggtg aagttcgttg 1680 ttttttttat ttttttaagt gattgttaaa cgtttatcgg ttggaattgt tttggtaagt 1740 ttagaatttt cgttttcgat tttttaattt cgtagaagaa tacgcgtatt tagtatagat 1800 tagtttattt tagcggtttt tttagttttt tattttttat tgttttagat ttttaatatt 1860 atttattttt atttagagaa ataaggggaa ttgttgtagg ttcgggggtg aggggtggtt 1920 ttgggatggg tagaaagtgt aggtgtagta ggaaattttt gtatgtttgc gtttatattg 1980 gagttgcgag gattttgaga aatattaaac gggatggttt tttgggttta ttgttttgaa 2040 agagtattaa ttttagggga aatattgaaa tagaagtttt gttattatta aagaaaaaag 2100 ttttattagg atgaggaaga aataatttta tgagaaagaa tgagcgagaa agtaataaat 2160 taaatggtga ttgtagggga atcgttgatt tttggtaaag gtgttatgag gtcgtattgg 2220 tttttcgttg aagattaggt tatatagatt ttagaggagt tgggttttaa tagaattttt 2280 tttttttttt tttttttttt tttttttttt tttttttttt ttttatttat ttattttttt 2340 ttttttttta tttttttttt ttttaggcgg taaaagatat tggttttgta gtttagatat 2400 gttttttttt ttgttttttt aagttttaag gtagtatagg ggagttgaga aaaagaatat 2460 tttgcgggtt ttttaggtcg gagtgggtat gattgaggtt ggttaggttt tatgtaggcg 2520 agtcgagggc ggaatcgatt ttagtgggcg ttgatttttt tatttttgga taggtttttg 2580 tggagtgggt taggtatttt ttttgttcgt tcgggttttt ttagattttg acggcgaacg 2640 tttggtaggt ttcgttttgt tgaagttttt taattaaata gggttagagg atgggagttg 2700 ttgtattttt agttggtata gtatttcggt ttgatagttt gtagtatatt gggtagaatt 2760 gtggtgtaat ttttttggta ttttaaattt cgttaatatg tttgggtatt gttttttagg 2820 <210> 36 <211> 3104 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 36 gcgggcgttg tcgagtacgg ggaggtgttg aaatagtttt ggcgtgttga tttaagtttt 60 gattggtaga gttattcggt gattgatagg gggtttttat ggcgttcgcg tcgttaattc 120 gtttatttta atagcggagt tagttcgttt gtcggcgtgt ttgagtcgag tcgagttcga 180 attttaagtc gcggagttag tatttttttt agtcggggtc gttcgttttc ggtcgttgag 240 ttatcgtcgt tattcggtag tgtgtttcgt tgttttaatt cgttttatta ataagcgttt 300 ggtatattta gttaggttcg cgggtatttg ttgcgtgttt cgtttcgggt ttagtgtttt 360 cgtcgtcgtc ggtattgttt cgatgtttta gttgtttatt ttgaatttta gtttttagta 420 agtggtcggg gtatgtgaga ttttggaaga gagcggcgat gtggagcgtt tgggtcgttt 480 tttttggtcg ttgttcgtgg tttttgcggt ttgcgaggtt tttaataaga atgagtcggt 540 gttacgcgta cgagttatcg tggtttttta cggtggtaat tatcgcgagt tttattatat 600 tttggaaaat tataagttta ttaaggagtc gtacgttaag ttgtaggcgt tgtggtttga 660 agtatattat taggaggttg agaagttgcg tggaagattt ttgggatttg tggataagta 720 tcgagtaagg aagaagtttt cgttgtcgcg tattatttgg gacggcgaat agaagatata 780 ttgttttaag gagcgtacgc ggtatttgtt acgcgagtgg tatttgtagg atttatattt 840 taattttagt aaaaaacgtg agttcgttta ggtaatcgga ttgattttta cgtaggtggg 900 taattggttt aaaaatcgtc gataaaggga tcgagcggtt gtagttaaga ataggtcggt 960 atttagaggt tttcgcgttt tgagcgtatc ggggaggagg cgggtggagg tatttttggc 1020 gtttttattt agtttttggc gattttaatt tagtaggagt tgggagcgcg gtttgttttg 1080 ggttaagagt tttgcgtttt gggtttttgg tcgggagttt ttttgtcggt tttgtttttt 1140 tattcgttgg ttttttacgt ttgcgggtag ttgtagtagt tggtttcggt tattaaatta 1200 aggttttatt gggacggaga ggggaagaga aataaaaaat taaaatttta taaatagtta 1260 gggattttaa gatttaaagt taatttttgt tagtttgggt ataggttttt attattaatc 1320 gaagtttggt ttattagtaa tgtgtcggtt ttatgttaat tattattttt aaagtttagg 1380 tatatttttt tttaatgttt tgaaaatagt ttttaatgga tttttgagaa atgggaagtc 1440 gagttttttt ttttttatgc gttgtttgtt atttttgttt taaaatagta aattagttcg 1500 tgggtcgagg tttttcgttt ttcggagtgt ggatttcgat tagttaaata ttttgcggaa 1560 gagttcggtt ttatttttta ggtttaaatg ttttttataa ttttttttgt ttttaggtcg 1620 ggtcgattcg atttaacgcg atcgcgggag tatttgttta ggcgtaagtt ttaggtagac 1680 gtatcgttag aaatggtatt ttatgttttt gggatcgatt tgtttttgtt atttatattt 1740 cgtttatttt ttgatagttt tgtaaatttt ttaaaagtgt ataataaata gggaggatat 1800 tgtaagttta gtatataaaa gatttgggag ttgcggcgtt gagaaagggc gcgaattatg 1860 gtggggtata atagtaggga ttcgcggagg ggcggtcgcg gatttttgtt cgatttttgt 1920 cgttttgtcg agtaattttc gttttaattg ttggggtttt cggaagaatt tttagtcgtc 1980 gggttggagg gacgtaggag gtggtggggg cgggcgacgg gcggttgtgt tacgagttgt 2040 gattcgtgtt tttttttttt ttcgtagatt ttagtagtag gttttgttat agggtttcgg 2100 gcgggtatta cgggcggagg gcgacggtac gttagaggtg ttgggcgtcg ttattagttc 2160 ggtcgttagt ttatttagta aggcggttat tttagttatt tttattacgt ttagcgatag 2220 cgagtgcgat atttgagttg tttatttagg atgtttagaa gtagatttta gtgtaaaaac 2280 gagaaaaata aaatgaaaga ggggaagaag atgagagatt tgtaaattta gcgttataga 2340 agttaggtga ttagggattc gcgggttcgg gttgtcgttt ttcgttttat ttcgcggtcg 2400 gtttggtttt attggcgttt tttggtcgcg attacgggaa ttagcgtgag gtttgattta 2460 gtattacgtt ttttttgttt tgtttttttt taaggatttt gttgtaaagt tttttcggaa 2520 ttcgaattgt aagttgagcg tttgtttaga tttttttatg ggtattttac gtcgaaagga 2580 cgttgttata tatgtataat tttcgtttta aagttttttt ttaataaaat atatatatgt 2640 tgtttattta tttatttaag agatcgttat ggtaggtttt tttgtagttt ggggaatttg 2700 ttgtttttaa atatgtaggt tggtggtgat gggttttgtg tggagaagtt aaataataaa 2760 ataatttagt gggtaatttt tttaattaag ggagttgttt ttagattttt ttttttttta 2820 ttattattaa tattattttt tttattaggt atgtagggat ttttgagtaa atggttttcg 2880 gaaggtttta tttatatatt ttttgttttt tttggtgttt tttggtatat gttttaaata 2940 atttatggta ggtttataat tattttttac gttaaattat acgtatgtgt atatatgtat 3000 gtatttatat aaatatatgt atgtatttat ataaatatat gtatgtatgt atatacgtga 3060 tatatttaag gttagaaatt ggtaatatgt gagcgttttt ttta 3104 <210> 37 <211> 3104 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 37 tagagaggac gtttatatgt tgttaatttt tagttttaaa tatattacgt gtatgtatat 60 atatatatgt ttgtataggt atatatatat gtttgtatag gtatatatat atatgtatat 120 acgtgtaatt tgacgtggga ggtggttata gatttattat aggttgttta aaatatatat 180 taggaagtat taaagaaggt aaaagatata taggtaagat ttttcggaga ttatttgttt 240 aagggttttt gtatgtttgg tgaagggaat gatattaata ataataagaa gaaaaggaat 300 ttgagagtag tttttttaat taagaaggtt gtttattagg ttgttttatt gtttggtttt 360 tttatataga atttattatt attagtttgt atgtttagaa atagtaagtt ttttaagtta 420 tagagaaatt tattatggcg gttttttaaa taagtaaata aatagtatat atatgttttg 480 ttaaaaaaaa attttaaagc gaaagttata tatatgtaat agcgtttttt cgacgtgaaa 540 tatttatggg agaatttggg taggcgttta gtttgtagtt cgggtttcga agagattttg 600 tagtaaaatt tttaggaaaa agtaaagtaa gaagaacgtg gtgttgggtt aggttttacg 660 ttggttttcg tggtcgcggt taaagggcgt tagtgaagtt aggtcggtcg cggggtgggg 720 cgggaaacgg taattcgagt tcgcgggttt ttggttattt ggtttttgtg gcgttggatt 780 tgtaggtttt ttattttttt tttttttttt attttgtttt tttcgttttt atattggaat 840 ttgtttttga gtattttgga tgggtaattt agatgtcgta ttcgttgtcg ttggacgtga 900 tggagatggt tgaagtggtc gttttgttgg atagattggc ggtcgggttg gtggcgacgt 960 ttagtatttt tggcgtgtcg tcgtttttcg ttcgtagtgt tcgttcggaa ttttgtgata 1020 ggatttgttg ttggagttta cggggaagaa agggaatacg ggttatagtt cgtaatatag 1080 tcgttcgtcg ttcgttttta ttattttttg cgttttttta gttcggcggt tagaggtttt 1140 ttcgaagatt ttagtagtta aggcgaggat tattcggtaa ggcgatagag gtcgggtagg 1200 agttcgcggt cgttttttcg cgggttttta ttgttgtgtt ttattatgat tcgcgttttt 1260 ttttagcgtc gtagttttta ggttttttat atattgggtt tgtagtgttt tttttgtttg 1320 ttgtgtattt ttgggagatt tataggattg ttaggaaata aacgaagtgt gggtgataag 1380 gatagatcgg ttttagggat atgggatatt atttttaacg gtgcgtttgt ttggggttta 1440 cgtttgagta agtgttttcg cgatcgcgtt ggatcgggtc ggttcgattt aaaggtaaaa 1500 aggattgtaa ggagtatttg ggtttggggg atgaggtcgg gttttttcgt aaaatgtttg 1560 gttaatcgag atttatattt cgggaaacga aaagtttcgg tttacggatt agtttgttgt 1620 tttgagataa gagtggtagg tagcgtatgg gaagaggaaa attcgatttt ttatttttta 1680 aaagtttatt gaaaattgtt tttaaagtat tagggaggga tatatttggg ttttgaaaat 1740 gataattaat atgaaatcga tatattgtta ataagttagg tttcgattaa tagtaggagt 1800 ttgtgtttag gttgataaga attagttttg ggttttgggg tttttaattg tttgtaggat 1860 tttaattttt tatttttttt ttttttttcg ttttagtgaa gttttggttt ggtgatcggg 1920 attagttgtt gtagttgttc gtaggcgtgg ggagttagcg ggtggggaag tagagtcggt 1980 aagggaattt tcggttagga gtttagaacg tagggttttt aatttaagat agatcgcgtt 2040 tttaattttt gttgaattgg agtcgttagg gattgggtaa gggcgttaga ggtgttttta 2100 ttcgtttttt tttcggtgcg tttaaagcgc ggaggttttt aggtatcgat ttgtttttgg 2160 ttgtagtcgt tcggtttttt tgtcggcggt ttttgaatta gttgtttatt tgcgtagggg 2220 ttagttcggt tgtttgggcg agtttacgtt ttttgttggg gttagggtat ggattttgta 2280 ggtattattc gcgtagtagg tgtcgcgtgc gttttttgaa gtagtgtgtt ttttgttcgt 2340 cgttttaaat ggtgcgcggt agcgggaatt ttttttttat tcggtatttg tttataggtt 2400 ttaggggttt tttacgtagt tttttagttt tttggtagtg tgttttaagt tatagcgttt 2460 gtagtttggc gtgcgatttt ttggtgaatt tgtggttttt taggatatga tagagttcgc 2520 ggtagttgtt atcgtgaaag gttacgatgg ttcgtgcgcg tagtatcgat ttatttttgt 2580 tgagggtttc gtaggtcgta ggggttacgg gtagcgatta gaggaagcga tttaggcgtt 2640 ttatatcgtc gttttttttt agggttttat atatttcggt tatttgttgg gggttgaaat 2700 ttaagatggg tagttggaat atcgaggtag tgtcggcggc ggcgagggta ttgagttcgg 2760 agcgggatac gtagtagatg ttcgcgggtt tggttgagtg tgttaggcgt ttgttgatga 2820 ggcggattgg ggtagcggga tatattatcg ggtggcggcg gtggtttaac ggtcgggagc 2880 ggacgatttc gattggagga ggtgttggtt tcgcggtttg gggttcgggt tcggttcggt 2940 ttaggtacgt cggtaggcga gttggtttcg ttattggggt gggcggattg gcggcgcggg 3000 cgttatggag attttttgtt agttatcggg tggttttgtt aattaaagtt tgaattagta 3060 cgttaggatt attttagtat tttttcgtgt tcgatagcgt tcgt 3104 <210> 38 <211> 2378 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 38 attttgagat tttagttgat tttttttgtt ttgtaattag aggggattgt gatttgggtt 60 aatttttttt ttatgggttt tagtggagtt agttgtggaa tggaatatta atttttattt 120 tataggtatg ttgtgaggtt tcgttaagaa atagttataa aagggtttta agagttatga 180 tgattgtttt aattatttag tagggagggg gtatttagcg gtgttgtttt tacgtatcga 240 tgttacgtgg ggcggggagg cggggcggag aacggagagc gtttttttat tttttatttt 300 ttttttttaa gtttagcgta gggggaggtg gttgcgattg attgaggggt tagggaaggt 360 tggttagggg cgtgggcgtg gttggggacg gtttgggggt ggggttgcgt aggaggttgg 420 aggagtttcg cgggatttag aggcggggcg tcggttcggg gattattgtt ttttcggggc 480 gtggttgtag gaggttggag gagtttcgcg ggatttagag gcggggcgtc ggtcggggat 540 cgttgttttt tcggggcgtg gttgttgtcg agtatttttt agtttagtcg agttcgtgtt 600 taggttacgt tttgttttag tcgtcgtttt ttttatttta cggcgttcgg agttattttt 660 cgtttgttcg tttttttttt tcgtttattt tttgtatttg ggtttgtatt atttttgtta 720 atcgtttttt cgattttgtc gatatttttt ttttaaattt ttgatcggta tttttgtttg 780 gtattttttt ttttattttt ttttttttat tttttttttt cgattttttt cgggtttttt 840 tttttttaaa attcgggttt tttcgcgtgg tttcgttttt aggtcgggga tgtttttcgc 900 ggtttcgcgt ttatggtttt gacgttgttt tttttcgttt ataagttgtg tcgttttttc 960 gttatgtcgg gtttacggcg gggcgtcgag cggttggcgg tgtttgggtt agatgggggc 1020 ggtggtacgg gtttatggtg ggttgcgggt ggttcgggtt cgcgaaagtg tcgtcggggg 1080 taggtatcga ggtgtaggac gttttggagc gcgcgttgtc ggagttgtag taggttttgt 1140 tcgcgttgaa gtaggcgggc ggcgcgcggg tcgtgggcgt cggtttggtc gaggtttttt 1200 aattggtgga ggaggtttgg ttgttgcggt cgtgggtcgc gaggtagttt agggtttgtg 1260 cgacgttatt cgtttcgatg gcggtttcga tttgttgttg cggttgttgt aggcgtcgga 1320 gttggagacg cgtgtgtagg tcgcgcgttt gttggagtag attttggtgg ttgagaatcg 1380 gtgagcgcgt taggtcgggg ttgggagagc gtcgcgtggt gtggatagtt aagcgtttgc 1440 gttttcgtgt gttttgcgtc gtgtttttgt tttttttatt tttttgattg tttgtattat 1500 atttttgtta ggggttagtt tgtttgtttt atagataagg aaattgagtt ttgggaaagt 1560 ttagtgattt gtttagtgga ttatagtgaa ttaagatttg tttttagggt tagtggggtg 1620 aggaatggag ttataggata ggagttcgtt tttggtttta tggatggaga tggtatttta 1680 ttgttaattt tttttttttt tcgtttttta agtttatagt tttttttttt atcggtttgg 1740 gttttcgttt atgatatttt ttttcgttat tattttattt tttttttaat gagagaagaa 1800 gggaaatata acgtttagaa aagagggagg gagatttttt tttttttttt tttttaggtt 1860 gtaaggcgtg ttggtttgag gttgtttatt ttttttttgt cgttttaatt taatttttgt 1920 tttatttttt attttggttt ttgtaatagg ttagatatga ttttattttg tagttgttga 1980 tgggaaatag ttttttgttg ggaggtatgg gtgggggaag aggatatcgg ggtgtagagt 2040 tcggcgggga ttaggtagag tgtgtgtttt ttttttttat tttatttagt attaagatgt 2100 cgtaagaggg ttaaatagag gtttggttgt tatttttgta tgttttttgg gatttttttt 2160 ggagtatgaa gatttttaag gatttatttt tttttttttt tgatgttaga gtagattaag 2220 ttgttatatt ttagttttat gttgaagttt ttagtttttt aagtttagaa gagtttttgg 2280 aagagttatt tttagtttat gtagttttta taagtgtgaa gggagtgggt tgggggtgtt 2340 ttttttgtta ttttcgaaaa gaaaaaaatt atttggtg 2378 <210> 39 <211> 2378 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 39 tattaggtaa tttttttttt ttcgaaaatg gtaaggaaaa tatttttaat ttattttttt 60 tatatttgtg agagttgtat gagttgaaag tgattttttt aaaaattttt ttaagtttga 120 gaagttggag attttagtat gagattggag tgtgatagtt tggtttgttt tggtattaga 180 agggagggaa agtgagtttt tggaggtttt tatattttag gagagatttt aagagatatg 240 taagagtggt aattaggttt ttgtttgatt tttttgcggt attttggtgt taagtggggt 300 gaagggagag aatatatatt ttgtttggtt ttcgtcgggt tttgtatttc ggtgtttttt 360 ttttttattt atgtttttta gtagaaaatt gttttttatt agtagttgta gaatgagatt 420 atgtttggtt tgttgtaaga attagaatga aggatggagt agaagttgga ttggggcggt 480 aagaagggag taagtagttt taggttagta cgttttatag tttggggagg agggaaagga 540 gaggtttttt tttttttttt ttgagcgttg tgtttttttt ttttttttat tgggagaggg 600 atgggatgat ggcgagagaa ggtgttatag acgggaattt aagtcggtgg gaaggagagt 660 tgtgggtttg gggggcgggg gagagggaga attggtaata ggatgttatt tttatttata 720 gagttaggga cggatttttg ttttgtaatt ttatttttta ttttattagt tttgggagta 780 aattttagtt tattgtgatt tattgagtaa gttattaaat ttttttaagg tttagttttt 840 ttatttgtga aatagatagg ttgattttta atagagatgt agtgtaggta gttagagagg 900 tgagggaggt aaaggtacgg cgtaaggtat acgggaacgt aggcgtttaa ttgtttatat 960 tacgcggcgt ttttttaatt tcggtttggc gcgtttatcg gtttttagtt attaggattt 1020 gttttagtag gcgcgcggtt tgtatacgcg tttttaattt cggcgtttgt agtagtcgta 1080 atagtaggtc gaggtcgtta tcgaggcgga tggcgtcgta tagattttgg gttatttcgc 1140 ggtttacggt cgtagtagtt aggttttttt tattagttgg aagatttcgg ttaggtcggc 1200 gtttacggtt cgcgcgtcgt tcgtttgttt tagcgcggat aaggtttgtt gtagtttcgg 1260 tagcgcgcgt tttagggcgt tttgtatttc ggtgtttgtt ttcggcgata ttttcgcggg 1320 ttcgggttat tcgtagttta ttatgggttc gtgttatcgt ttttatttgg tttaggtatc 1380 gttagtcgtt cggcgtttcg tcgtgggttc gatatggcga agaagcgata tagtttgtag 1440 gcggagagaa gtagcgttag gattatgggc gcggggtcgc gggggatatt ttcggtttgg 1500 aggcggggtt acgcggagag attcgggttt tgggaaaaga gggattcgag aggggtcggg 1560 gaaagaagat ggagggggag gaatggagag aagggtatta ggtaagggtg tcggttagaa 1620 gtttggggga ggagtgtcgg taggatcggg ggagcggttg gtaaaggtga tgtaggttta 1680 gatgtaggga gtgggcgaaa ggagagagcg agtaggcgag ggatggtttc ggacgtcgta 1740 gggtagagga ggcggcggtt ggaataaagc gtggtttggg tacgggttcg gttgagttgg 1800 gagatgttcg gtagtagtta cgtttcggag gagtagcggt tttcggtcga cgtttcgttt 1860 ttgggtttcg cggggttttt ttagtttttt gtagttacgt ttcggaggag tagtggtttt 1920 cgggtcgacg tttcgttttt gggtttcgcg gggttttttt agttttttgc gtagttttat 1980 ttttaagtcg tttttagtta cgtttacgtt tttggttagt tttttttagt tttttagtta 2040 gtcgtagtta tttttttttg cgttggattt ggaggaaggg ggtggagaat gagaggacgt 2100 ttttcgtttt tcgtttcgtt ttttcgtttt acgtgatatc ggtacgtggg agtaatatcg 2160 ttggatgttt tttttttatt aaatggttaa aataattatt ataattttta aggttttttt 2220 atggttgttt tttagcgaaa ttttataata tgtttatggg gtgggaattg atgttttatt 2280 ttatagttga ttttattgaa gtttatgagg aagaaattgg tttaaattat agtttttttt 2340 gattatagaa tagaaaaagt tagttaaaat tttaggat 2378 <210> 40 <211> 2436 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 40 agttttggat gataaggatt aattgtttag ggcgttggtc gagaggaata ggaagagcgt 60 ttcgtggagt agggcgggcg agaagagtcg ggcggtcgcg gggttttcgc gtatgttggg 120 taggaagagg aagagttgta gtacgaaggt tattagggag atgtataaga agtaggcggg 180 ggttattacg ttgagtagtc gtagggttag tattttcgat tatatttttg cggggttcgg 240 ggtgagaaga ggattgattg attacggcgt ttagggggcg ttttcgttcg ttttttcgtg 300 tcgcgcgttt ggggtattgt acgcgatttt acgtttttaa ttttttgttt cgcggatttt 360 ttttttttag ttttttaatt tcggattagg taggttagag attcgagttc gtagcggttt 420 cgggtttagg ttttatttgg gggtgagtgt tgtttggggt tttgagcgag ttcggcgttt 480 tggcgcggta gagtttggta taggagggag ggattcgttt gtagttttta ggagttgtga 540 gggtgggggg tatcggggga taggattttt tttttttgtg gatgtggaaa taagtttagg 600 tttgggattt ttggtttaga tttttttagg aggagaaagg gaaggatttg gggtcggggg 660 taggagaatt agcggtattt gatttgttgg aaattttgtt ttatattttt tttttttcgt 720 ttttgcgttt ttatttatat atatattttg ggtagtattt agggatttta ttaggttatt 780 taaggttttt tggaggtatg tgtgcgtgag ggattacgat gtgtgtgtgt gtgtttttgt 840 ttgtgatttt gtacgtgtaa tttgtgtgcg tttgagtatt tgtatttgtg tatgtatata 900 tttgcgtgta tagatacgta gtttttgtta tttagtttta aaaaaattaa ttgaaataat 960 cgatatattt atattcgttt tcgggtatcg ggtgaggtgg gggcgtaatt agaatatttg 1020 tgttagcggg ttttggttag tatatttttt taacgttggt tgttcgggtt atttttttgc 1080 gaagagcgtt tttatttgag gcgaaattaa aatttttttt tcgcgttcgt ttttcgtttt 1140 tttgttgaga gaaatttaaa taatttttat ggcgtcgaaa ttttttttat gtcgataagt 1200 tcgttttggg cgtacgagtg gatgtttggt tagttttttt tgggatcgat ttcgtcgtcg 1260 tgtttagttt ttattacgtt tttattttat tttacgtttt atagtcgggg tttttggtta 1320 gtttcggaag ttatcgagaa ataggatttc gtgcgttcga gagaattttt ttaggggtta 1380 aggaatcggt tagtcggagg cgcgagaaaa gttttgggaa ggcggttgta tttaggatgg 1440 gtggatgtta cggggttttc gtttaggttg tttcgttcgt acgggtcgat tggttatttt 1500 ggaatttttt ttgtaggttt tagcgttttt cgggaattcg tagttttcgc ggagagcgtg 1560 ggtttttttt tatcgttggg gcgtagcgta gtgtacgttt gagggtggtc gtcgggggtt 1620 gggtacgttt ttagttttgc gtcgtcgggg gttgcggcgg tgttgtttat tttagagagt 1680 tttcggtttg gggtttcggc gaagtaagtg ttttttcggc gtcggtcgtt aggggggcgc 1740 gggagtagtt agatgcgtcg tagcgttggg aaggcggcga aggatagggg ttaggggagt 1800 gaggggcgtt cggtaggtag ttttagtttt ggttttgcgc gggagaaggg atagtagaga 1860 tcgttcgtgg ggtttcgggg tgtagggagt tgttcgttta gttttggcgt tcgtttcgtt 1920 cgcggtagag ggcggtatag tcggagtttt ggaaagatcg gtagcgtcgg tagtcgcggg 1980 tttttcggtt attgtttttc ggacgtacgg gaagtcgttt ttcgcgtcgt cgtcgtcgta 2040 ttgtcgtcgt cgtagagggg tgaggaaatt aatttatcga gttttggtcg tcgataagag 2100 gagtttcgga cgtcggtttt cgttttgttc gaggttgtaa agttgtggat tcggttcggt 2160 tggttcgtag tttgcgtttc gtttcgggaa ttgggtaagt agcggggatg tggggaggag 2220 ggagcgggta gttgttggtt ttttatttgg gcgttagcga gtaagggtta ggaagcggcg 2280 gggatggtag ttgggtattt tttagtttcg ttattttttt tttcgttttt gggggcggtg 2340 ttttggtcgt tagttttagt atcgtggatt tgtttttttt ttttttttcg attttttttg 2400 agcgggttgg ggcgttttgt ttggttttag cgttcg 2436 <210> 41 <211> 2436 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 41 cgggcgttga aattaggtag ggcgttttag ttcgtttaag gggaatcgag aggggaggag 60 ggggtaagtt tacgatgttg agattggcgg ttagagtatc gtttttagga gcggagggag 120 gggtggcggg gttggggggt gtttagttgt tattttcgtc gttttttggt ttttattcgt 180 tggcgtttaa gtgggaagtt agtagttgtt cgtttttttt tttttatatt ttcgttattt 240 gtttagtttt cgaagcgaag cgtaggttgc gagttagtcg ggtcgagttt ataattttgt 300 agtttcgggt agggcgagag tcggcgttcg gggttttttt tgtcggcgat tagagttcgg 360 tgagttgatt tttttatttt tttgcgacgg cggtagtgcg gcggcggcgg cgcggggggc 420 ggtttttcgt gcgttcggga ggtagtggtc gagaagttcg cggttgtcgg cgttgtcggt 480 ttttttaagg tttcggttgt gtcgtttttt gtcgcgggcg aggcgggcgt tagggttgaa 540 cggatagttt tttatatttc ggggttttac gggcggtttt tgttgttttt tttttcgcgt 600 agggttaggg ttgaggttgt ttgtcgagcg ttttttattt ttttagtttt tgtttttcgt 660 cgttttttta gcgttgcggc gtatttggtt gttttcgcgt ttttttggcg atcggcgtcg 720 ggaaggtatt tgtttcgtcg gagttttagg tcgagggttt tttggggtgg gtagtatcgt 780 cgtagttttc ggcggcgtag gattgggggc gtgtttagtt ttcggcgatt atttttaggc 840 gtgtattgcg ttgcgtttta gcggtaggga gaggtttacg tttttcgcgg aggttgcggg 900 ttttcggggg gcgttgggat ttgtaaaggg gattttaagg tgattagtcg attcgtgcgg 960 acgggatagt ttggacggag gtttcgtggt atttatttat tttaggtgta atcgtttttt 1020 tagaattttt ttcgcgtttt cggttggtcg attttttagt ttttggaaaa gttttttcgg 1080 gcgtacggaa ttttattttt cggtggtttt cgaagttggt taggaatttc ggttgtgagg 1140 cgtggggtgg gatggggacg tggtgagggt tgagtacggc ggcggggtcg attttaggaa 1200 aggttggtta agtatttatt cgtgcgttta gggcgggttt gtcggtatgg aaaggatttc 1260 ggcgttatga gggttgtttg ggtttttttt agtaggaggg cgggaggcgg gcgcgaaggg 1320 gggattttaa tttcgtttta aatgaaaacg tttttcgtaa agaaatagtt cgggtagtta 1380 gcgttggaga gatgtgttgg ttaggattcg ttgatatagg tattttggtt gcgtttttat 1440 tttattcggt gttcgagagc gagtgtgagt gtatcgattg ttttaattga tttttttaaa 1500 gttagatagt agaggttgcg tgtttgtata cgtagatata tatatatata aatatagata 1560 tttaagcgta tatagattat acgtatagag ttatagataa ggatatatat atatatatcg 1620 tggtttttta cgtatatata tttttaaaga gttttgggta atttggtgag gtttttgagt 1680 gttgtttaag atgtgtgtgt gggtggggac gtagggacgg agaaagggga gtgtgaagta 1740 ggatttttag taggttaagt gtcgttgatt tttttgtttt cgattttaaa tttttttttt 1800 ttttttttta gggaggtttg aattagaaat tttaaatttg ggtttgtttt tatatttata 1860 gaggggagga gttttatttt tcggtgtttt ttatttttat aatttttaaa gattgtaaac 1920 gagttttttt tttttgtgtt agattttgtc gcgttaaggc gtcgagttcg tttaaaattt 1980 taggtaatat ttatttttag gtggggttta gattcgaggt cgttgcgggt tcgggttttt 2040 ggtttgtttg attcggggtt agggaattgg ggaggggaaa ttcgcgggat agggggttgg 2100 gggcgtggag tcgcgtgtag tgttttagac gcgcggtacg gaggagcggg cgagggcgtt 2160 ttttggacgt cgtagttagt tagttttttt tttatttcgg gtttcgtagg aatgtaatcg 2220 aggatgttgg ttttgcggtt gtttaacgtg gtggttttcg tttatttttt gtgtattttt 2280 ttggtgattt tcgtgttgta gttttttttt tttttgttta gtatgcgcga ggatttcgcg 2340 gtcgttcggt ttttttcgtt cgttttgttt tacggggcgt tttttttatt tttttcggtt 2400 aacgttttgg gtaattagtt tttgttattt agaatt 2436 <210> 42 <211> 2804 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 42 ttaaggtttg ttggatttga ggttgtttgg ggtgttaaat agatttattt atgagtatat 60 ttggttaata tatttaagtt taatagtggg tgggattttt ggttggtttt gatttttttt 120 atagtgtgtg taaatgggta tttattagat tttttttgtt tgttttttta tttgtaaatt 180 ttgaaaggag agtatttttt ggggtgattt tgaaaattat gttagaattg aaaaggtttg 240 tgtaaatgtg aggtgtaatg atgatttatt agaagtagtt agttttgtat gtgtttgtag 300 gatagatgtt agaatgtttt ataaatgtgt gtatatatat attatgtatg tgtgaaggtg 360 tatatttgtt tttagatatt tgataaatgt atatatgtat gtgtgtattt ttggttgaga 420 gtaaaggggt taatataggg tttatatagg atattatttt gtagttttgt gtgtgtatag 480 tatatatgtg agtatgattg tttgtgtttg gagatattgt atggtattgg aggagttgtt 540 tagttgttgg tgttatttgg gaagtagggt tttgggtgtt gttttggagt gtgggaaagt 600 ttggatttgg gtttgttggt tagtgttttg gtgttgttgg gtttttttat tttttatttg 660 ttggttggtg agtggtttta gttttaagat ttttgatttt gttggtgagg ggagggagtg 720 agaaggagtg tgttttgggt ttaagaggtt gtagggtttt attttttagg tttgttgttt 780 tttttttatt tttttaggtt atatttttat ttaaaataaa gaagggtgtt tgatttattt 840 aggttaggga agttggtttt tgggagtttt ttgtttttat aagttatggt gaagggaggt 900 gaagttaggg tttgttatgg tttgggagaa aatgtggttg tagggttttt ttgggttgta 960 gtgttggttt ggggttttaa gattgttaag gtgtgtgtgg gaggtgtgta gtgtggttat 1020 tgaagagttt tttattattg tattggtagg ttgttgggtt tgtttttttt ttatgttttt 1080 aagggttttg agttgtgtag tatttgtatt atttagaagt gtttgtggag aaaatgattt 1140 taggtgtaag tttaaggttg ttgtttgtaa aggtaatgtt gtggagattg ggttttatag 1200 tgatttgggt ttttaagtta ttgaaagtta tagggtaggg ttataaatat ttttttgttt 1260 tttttgtaga attgtgtggt tgataggaga gtgttgtgta gaaaatttga ggttgggtgt 1320 tggaggagtt tttgtggttt ggagaaggta tagaggtgtt tttgagaggt gtagttggaa 1380 taggtgatgt atgggtttgg atttggttgg ttaattgagt ttagtggttg tgaaaattag 1440 agttgttata gaggttgagt atgattttat ttttggggat tgggtttggt ggggagttat 1500 tgtttttaat gtttttagag attttaagta ggataatata atgttggtag gagtaaggtg 1560 taaggaattt agtggtagaa gttttttggg ggggtgggga aaggtagatt tgtgttttgt 1620 ttgagtttgg gggtggggat agtttttggt tttgtagttt ttgttttggg gattagttgg 1680 gtttatttaa tttttttata tggggttgaa aggggttaat gggatggttt tgttgttttt 1740 tttttgggat tttatagggt tttgatttgg tttttatttt tgtatggtta gtagttgtgg 1800 gggttttagg aaggaggata aaggtttggt gttattgtgg gtgggggttt ggttttttgg 1860 ttttttgttt atatttatag tttttagtgg ttgttggggg aagattttta aaaatatgtg 1920 ttgaattttt tttttttttt ttttagaaat aaataaataa aaaaggtaaa aggtgaattt 1980 ttttttattt tttgtttata gagattaaag ttttttggga ttttgttttt tttttttttt 2040 tgattgttta gaaatatttg tttttttttg tatatagagg aaaatgtggg gaaaggtttt 2100 ttaaaatttg gttttatatt attattatta ttaaggataa ttgggtaggt tgaggtttta 2160 atgtggatga tttgagttgg ttttgtgttg gggttttgta gttattgttt tgtgtgttta 2220 gtatttttgg gggtgattag ggtttttgtg tttttgtttg ttgtttggta gttgagagta 2280 ttttgtgttt agattggttg atttattttt ttttgaattt tgtttagagt tggtaagggg 2340 gatttagttt gtgttttaag atttgggttt gtagtgttgt taataggttt ggggatatga 2400 ggtgttttag gttggggttt ttttggttgt tggttttttt tgttttttat ttgttggtgg 2460 tgttttggtt gtttgtaatt gatttaattt gttttttgtg tttgtttttt aggttttttg 2520 tttttttata aaggtttagg ggagttttgt ttataggttg attttgtaat ttttggtttg 2580 gtggttattt tttgtttttt tgaaaaagaa aaggaaaaaa aaaaaaaaaa agaaaaaatt 2640 aattagttga gggaggtgtg tgaggattgg aggtgttagt tggatagttt atgagtaggt 2700 ttttgggttg gtgttgtttt gtgggttagt atggtttttt ttagagaaaa ttttttaaat 2760 gtgtgaagat tgttttgggg gaagtgagag ggaggttgga ggag 2804 <210> 43 <211> 2804 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 43 tttttttaat tttttttttg ttttttttaa agtggttttt atatgtttag gaggtttttt 60 ttgagaaagg ttgtgttgat ttgtgaagtg gtattgattt agggatttat ttataggttg 120 tttggttggt gtttttagtt tttatgtgtt ttttttgatt ggttgatttt tttttttttt 180 tttttttttt tttttttttt tttagaaaag tagaaggtag ttattgggtt agaggttgta 240 gggttagttt gtgggtgagg tttttttagg tttttgtgga gaaatgggaa atttgagggg 300 taaatgtagg aagtgggttg ggttaattgt gggtgattga ggtgttgtta gtgggtgggg 360 agtgagaggg gttagtagtt gggaagattt tggtttggag tgttttgtgt ttttgggttt 420 gttggtggtg ttgtaagttt aggttttggg gtgtgagtta agtttttttt gttagtttta 480 aataaaattt gggggagaat gagttggtta gtttgggtat agggtgtttt tgattgttgg 540 gtggtgggtg gaagtgtagg ggttttgatt gtttttagag gtgttgagtg tatagggtag 600 tggttgtaga gttttggtgt gaggttaatt tggattattt atgttgggat tttagtttgt 660 ttggttgttt ttagtaataa taatagtatg aaattgagtt ttaaaaaatt tttttttgta 720 ttttttttta tgtataaggg agaataagta tttttaggta gttaaagaaa aaaaaagggt 780 aggattttag gaaattttaa tttttatgga tgaggagtga aggggaattt gttttttgtt 840 ttttttgttt gtttgttttt agaagagaaa aaaaggaaat ttgatatata tttttaaaaa 900 ttttttttta ataattgtta aaggttgtga gtgtgagtag agagttagga aattgagttt 960 ttgtttgtgg tgatattggg tttttgtttt tttttttgaa gtttttgtga ttgttgattg 1020 tgtagagata aaggttgggt tagggttttg tggaattttg agggaggggt ggtggggttg 1080 ttttattggt tttttttaat tttatgtagg ggggttaggt gggtttagtt gatttttgga 1140 ataggggtta taaggttagg ggttgttttt atttttaggt ttagatgagg tatggatttg 1200 ttttttttta tttttttgaa aggtttttgt tgttaaattt tttgtatttt gtttttatta 1260 gtattatatt gttttattta aagtttttgg aggtgttagg gatagtggtt ttttattgga 1320 tttgattttt agaaatggaa ttgtgtttaa tttttgtggt gattttggtt tttgtgattg 1380 ttgggtttgg ttggttggtt agatttgaat ttgtgtattg tttgttttag ttgtgttttt 1440 taggggtgtt tttgtgtttt ttttgggttg tggagatttt tttagtgttt ggttttgaat 1500 tttttgtgta atgttttttt gttagttgta tggttttgta gagaaggtgg gagagtgttt 1560 gtgattttgt tttgtagttt ttggtgattt aaaaatttag gttgttgtgg aatttagttt 1620 ttatggtatt gtttttgtag gtagtagttt tgggtttata tttgaggttg ttttttttat 1680 agatattttt gggtgatgtg agtgttgtgt agtttagaat ttttggaagt atgagaggag 1740 gatgagtttg gtggtttgtt ggtgtggtga tggagggttt tttggtagtt atattgtgtg 1800 ttttttatat atattttaat agttttgggg ttttgggtta gtgttgtagt ttaaagagat 1860 tttgtagttg tatttttttt taggttgtgg taaattttgg ttttgttttt ttttattatg 1920 gtttgtgagg gtaggaggtt tttgggggtt gatttttttg atttgaatga gttaggtatt 1980 tttttttatt ttaagtgggg gtgtgatttg aggagataaa ggaaggatga tagatttggg 2040 gagtggggtt ttgtagtttt ttgggtttgg agtgtatttt tttttgtttt ttttttttat 2100 tggtaggatt gggggttttg aaattggagt tgtttattgg ttggtggatg agagataaag 2160 gagtttggtg gtgttgaagt gttgattagt agatttggat ttggattttt ttgtgtttta 2220 gagtagtatt tgaaatttta ttttttaggt ggtattgatg gttgagtagt ttttttggtg 2280 ttatatggtg tttttaggta tagatagttg tgtttgtgtg tgtattgtgt atgtataaga 2340 ttgtaggatg atgttttgta tgagttttgt attagttttt ttgtttttag ttagaggtat 2400 atgtatatgt gtgtgtattt gttaagtgtt tagggatagg tgtgtatttt tatatatatg 2460 tgatgtgtat gtgtatatat ttgtagaatg ttttagtatt tattttatag gtatgtatag 2520 ggttggttgt ttttaataag ttattattat attttgtatt tatataggtt tttttagttt 2580 tggtatgatt tttagaatta ttttgggaaa tatttttttt ttaaagttta tagatgagga 2640 aataagtaaa aagaatttaa tgggtatttg tttgtatata ttgtgagaga gattgaggtt 2700 agttaaagat tttgtttatt gttgaatttg ggtgtgttgg ttgaatgtgt ttatagatgg 2760 gtttgtttag tgttttaggt gattttaggt ttggtgggtt ttgg 2804 <210> 44 <211> 3952 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 44 ggttgtagtt ggagaggaat aggaattgta gtggggatgt tttggttttt gggtttatag 60 tatttgggat ggatgtgtag tagtgtgggt tgggaattgg gtattagggt gggatgggtg 120 agaggtttta agggataagg tagggagaag tgtagtgggg tgtggggaat tgtatgtttt 180 ttttttgttt ttgtttttta ttttgaggtg gtagggtggg tgggtgtggt tttgggggtg 240 ggtgggttgg gtggggtgga ggtggggttg tagtattggt tttatttagt tttttttgtt 300 tgtagttaga gtgagttgag ttgtggttag ttttggtggg tagggggggt gttggagtgt 360 agtgtagtgt agttttatta gtttgtaaag tggattgagt tggaagttga gtgttgttgt 420 gggaggtggg tgatgggggt aggtgttatt ggttgtgtta tggatgggtt gtgtttgttg 480 ttgttgttgt ttttgggggt gagtgttagt tggagggggt ttgttttttt ttttgggatt 540 agaattttga gaagagttgg gtgttgttat taaggaaata gaatagagta ttggggtttt 600 agatattgag ggtgggtggt gggaaaggat ttttgatgtt gggattatga aggagggttt 660 agggtttttg gagtgtagag gtgatttttt agggtggaga tgagggtaag attggagtat 720 ggatgttggt ttttaggtat tgtagggggt ggtgggggag ttgggagggg ttttttaaga 780 gggggtatgg ggttttttga tgtttaggtt ttttggaaga ggatatttga atgttgggat 840 tttgaaggga tttttttttt agtattttgg tttttggaga gttgtgggat agaattaagg 900 tgagagaagg agggggaatt ggatggggat tagagatgag aggggtgagt tgggttgggg 960 tggggagttt gggatgatgg gatggaataa tggaggaggt tggagggatt ggaggtagag 1020 gggatttggt aaggataatg gggattggtt agataatggg ggggaggggt gttggaggga 1080 gaggttgggg agtgggagag aggttgagaa gtgggttagg gagggtagaa gaggggtgat 1140 ggtgagggtg gtagagagat ggaagtagaa ggaaaggaga tagagtgggg tgtggatttt 1200 gaagtggttg gggttttgtt tgtttgttga gggatagtga gatgagaaga gagagtagag 1260 gtttggatat ttttagtgtt tgtttttgtg tttttgtttg tggttttttt tagttttgga 1320 attggggttg tggatttaag gttgggaggg gagtgtttat tttgttgggg tgaatttgtt 1380 tttggggttt ttttatggtt ggtgggtttt tttgatgtgt gtgtttttat ggtttgaagt 1440 agtgtagtgg attgtgaggg atggagtggg tgtgttttta tttgggttgg tggtggttat 1500 gttttggggt gtagagtgtt ggggtgtatt aggtggggat tttttttggt tgtgtgtagt 1560 tttggttatg taggtgggag gtggtaggta gggggtgttg tggggtgagg taagtgtagt 1620 ttgttgttgt ttgtttgtga gtttggggtt gtgtgttgtt ttttatttag ttgtgtgatt 1680 tgagtgttgt gtttattgtg ttttgtgggt ttttgtgttt tgaagggttg ggatttggtt 1740 tgagtttttt ttggtttttg gtgtaagttg ttgggtattt aatgagatgg gggtgtttgg 1800 atgttttgga ttttgtagtg tggtattttg ggttattgat ttggtaaagg ttggtgggtt 1860 ttttgggtgg tttgatgaga ttgttagatg tggtttgttt tatggttatg aattgaatgt 1920 tttggaaggt ttggtaatgg aggaggtgtt tttatttttt ttgttagtat tttttattag 1980 agtattgtgt tttaaatttt ggttttatag atatggagat tgaggttttg agagtttaaa 2040 tgatttggtt aagattttat agtaagttgg gttagagttg tggttagatt ttttgatttg 2100 atttttagtt tggtattttt ttattttttt agggggtagt tgttgtttta gtttggggtt 2160 atggttgtgt tttttagtag ggtggggggg gttgatattg tttttagagt ttgttggtgg 2220 tagagtttgt gggtgaggtg ggtagagatt ttgtttgggt gtgggtttta gtttgaaagt 2280 ttagttttag ttttttggag ttgttaggat ttgtggttgt gtttggggat ttgggagtga 2340 ttgtgggtat gtttgttgat taatgttgtt ggttagagat gttgtttaga tgtgggtggg 2400 tgagtgtaga ttaggagagt ggggaggagg gattggattt tagaggggta atgatttggg 2460 ttttgggttt gggtaagagt gagggttttt gtgtgaagat ttaaggaagg aggggagttg 2520 ggtgtggagg atttgggtgt ttgggaaggt gtattttgat aggaatttgt tgtttgtagt 2580 ttttgtggtt tttgtttttg ttttggtgtg tggttgtttg gtttgggatg gttgtgtgtg 2640 gtttgagttt ttttttgggt tgtggtgaga gagagagggt tgaaattaga gtgtgttttg 2700 gtgggttggt tggtgggttg tgttggtaat ggaggtattt tgttatttag atgtttgtaa 2760 ttagagttgt tgggttggtt aatgtgttta atagggatgg aatgagggta gtaaatgggt 2820 gtgtgtgagt ggttgggttg agttgggtgg atggtggatg gggaggtagt tttgtggggg 2880 atgggttttt attgtattgt tttagtttag tttggtttaa gtgttttgtt ttttttttgg 2940 gggattgtgt ggggaggtgg gaataattga tgtgttgagt ttttattaag tgttttgtat 3000 ttttttggta gttttttttg aattatttaa tttttataag gttttagtaa ggtgaattta 3060 gttattttta ttttgtagtt gaggaaatag aattttttag atttttaggt ttgagattag 3120 gtttttttag tgagttagtg gtggtgtttt tgttggaatt taggatgttt ggtttgggat 3180 gttttttttt ttatatatgt taggtttttt tttgtttttt attttttaga ttatggaagg 3240 agttgtggtt ttgagagatt aaattgtgtt ttatgttttt ggttttatat atttagattt 3300 gagttttttt tttatatgta gaggttttgt ttttttttaa gtttttatgt tatattattt 3360 tgggtaatta gttttttttt ttttaatttt ttttttattt aaagggagtg aggggtatgt 3420 gttagtgttt tttttgggtt tgtattgatt ttaaaaggtt ttttaggtgt ttgaaaattt 3480 tttttatttt atggtggtga ttatggtttt atttatttaa gagttttttg ttgaagttgt 3540 tggaatggtt agggttgatt atattgaaat atttgtatgg ttttaaatat ttttaattgt 3600 tttgttgttt tttttttttt tttaattaaa aaaaatgaaa atttttaaaa gttaatttat 3660 ttaaggattt ttttatttta gttttttgta agttttgaaa tggttaaaat aaaaagatta 3720 taagtgtttt taaaaatgag atgaaattat tttgttaaat gtgaaatgat taagtgtaat 3780 atatataaat tttagggaaa tttatttgtt atttttataa attaattttt ttggatttga 3840 ttttggagta attagtttga atgttagtta ttttttttta tttggttaaa tttttttttt 3900 ttgtttgggg tttttttaag atgagatgtt tttttgataa ttaatattta tt 3952 <210> 45 <211> 3952 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 45 aataaatgtt agttattaaa gaagtatttt attttaagga gattttaggt aggaggggag 60 agtttagtta agtagggagg ggtgattaat atttaggtta attgttttaa aattagattt 120 aaaaggatta atttataggg atgatagata aatttttttg aaatttgtat gtgttatatt 180 tagttatttt atatttgata gaatgatttt attttatttt taagaatgtt tgtaattttt 240 ttgttttggt tattttaagg tttataagga attaaggtgg aaggattttt agatgaattg 300 atttttaaga atttttattt tttttaatta gagaaaagag agaaatagtg aaatagttga 360 aagtatttga aattatatga atgttttagt ataattagtt ttggttattt taatagtttt 420 agtaaagagt ttttaagtga atggggttgt ggttattgtt atgggatggg agagattttt 480 aaatatttgg agggtttttt gaggttgatg taaatttagg ggaggtattg gtatatattt 540 tttatttttt ttggataggg gaggagttgg gaggaaagga gttaattatt taagataatg 600 tagtatagag atttgagagg gggtagggtt tttgtgtgtg gagaaggggt ttagatttaa 660 atgtgtgggg ttaaaggtat agggtatgat ttaatttttt agagttatga ttttttttat 720 gatttagaag gtagggggtg ggagggagtt tggtatatgt aggaaagaga atattttagg 780 ttaagtattt tgggttttaa taaagatgtt attattgatt tattggggga gtttggtttt 840 gggtttgaaa gtttagaagg ttttgttttt ttaattgtga agtgggaata attaaattta 900 ttttgttagg attttataag gattaaataa tttaagagaa attattaggg aagtgtaagg 960 tatttagtag gaatttagta tattgattat ttttgttttt ttatgtggtt ttttagggaa 1020 gaagtgaggt gtttgagtta gattgggttg gaatagtgtg gtaggggttt gttttttgtg 1080 gagttgtttt tttatttatt atttatttag tttagtttgg ttgtttatgt atgtttattt 1140 gttgtttttg ttttattttt attaggtgta ttagttagtt tggtggtttt ggttatagat 1200 gtttgaatga taaagtgttt ttattattgg tgtggtttgt tagttgattt gttgggatgt 1260 gttttggttt tagttttttt ttttttattg tggtttagga agaaatttgg attgtgtata 1320 gttattttag attgagtagt tgtgtgttga ggtggaggtg ggagttgtag gggttgtaga 1380 tggtaggttt ttgttggggt atattttttt aagtgtttag gttttttatg tttagttttt 1440 tttttttttt gggtttttgt gtggggattt ttgtttttgt ttagatttgg agtttaagtt 1500 gttgtttttt tgggatttgg tttttttttt ttgttttttt ggtttatgtt tgtttatttg 1560 tgtttgagta gtgtttttaa ttagtggtgt tagttagtag atgtgtttgt ggttgttttt 1620 aaatttttgg atgtagttat aggttttgat agttttaggg aattggggtt gagtttttgg 1680 gttggggttt gtatttggat agaatttttg tttattttat ttgtaggttt tattgttgat 1740 ggattttggg gatagtgtta attttttttg ttttgttggg aaatgtagtt gtgattttga 1800 gttgggatag tggttgtttt ttgaaaaggt gggggagtat tgagttggga attaggttgg 1860 ggagtttagt tatgattttg gtttaatttg ttgtgagatt ttggttaagt tgtttaaatt 1920 tttagagttt tagtttttgt atttgtaaag ttggaatttg gggtgtagtg ttttgatgaa 1980 agatgttggt ggggagagtg aagatgtttt ttttgttgtt agatttttta gggtatttgg 2040 tttatggtta taaagtaggt tatatttgat aattttgttg gattatttgg aggatttgtt 2100 gatttttgtt gagttggtgg tttgggatat tgtgttatag aatttgaggt gtttgggtgt 2160 ttttgttttg ttaggtgttt agtggtttgt attgagagtt aggagaggtt tagattggat 2220 tttgattttt tgaggtgtgg gagtttatgg agtgtggtgg gtgtggtgtt tgggttgtgt 2280 agttaggtgg ggagtggtgt gtagttttag atttgtaggt aggtagtggt ggattgtatt 2340 tgttttgttt tgtagtgttt tttgtttgtt gttttttgtt tgtgtagtta gagttgtgtg 2400 tggttaggaa gggtttttgt ttagtgtgtt ttggtgtttt gtattttgag atgtagttat 2460 tgttagtttg ggtaggggta tatttgtttt gttttttgtg atttgttgtg ttgttttaag 2520 ttgtgagaat atgtgtgttg gaggagtttg ttggttgtgg gggaattttg ggagtgggtt 2580 tgttttggtg aagtgggtat ttttttttta gttttagatt tgtagtttta attttgggat 2640 tgggagaggt tgtgagtagg agtgtgggga taggtgttgg aaatgtttaa gtttttgttt 2700 tttttttttg ttttattgtt ttttagtggg taggtgggat tttgattatt ttagggtttg 2760 tgttttgttt tgtttttttt ttttttgttt ttattttttt gttgtttttg ttgttgtttt 2820 ttttttgttt tttttaattt attttttaat tttttttttg ttttttaatt tttttttttg 2880 atgttttttt tttttattgt ttggttggtt tttattgttt ttgttgggtt ttttttgttt 2940 ttagtttttt tgattttttt tattgtttta ttttgttgtt ttgggttttt tgttttagtt 3000 tagtttgttt tttttatttt tagtttttgt ttagtttttt tttttttttt tgttttggtt 3060 ttgttttatg attttttaga gattgagatg ttgaggggaa agtttttttg ggattttggt 3120 atttgagtgt ttttttttga agaatttggg tattggagag ttttatgttt ttttttgaaa 3180 gatttttttt agttttttta ttgttttttg tggtatttga ggattggtat ttgtgttttg 3240 gttttgtttt tatttttatt ttggagagtt gtttttgtgt tttgggaatt ttagattttt 3300 ttttgtggtt ttggtattag aggttttttt ttattattta tttttagtat ttgggatttt 3360 aatgttttgt tttgtttttt tggtggtggt gtttggtttt ttttggagtt ttgattttgg 3420 gaaagggagt gggttttttt tggttaatat ttatttttag aagtagtaat agtagtaggt 3480 gtggtttgtt tatggtgtgg ttggtggtat ttgtttttat tgtttgtttt ttgtggtagt 3540 gtttgatttt tagtttggtt tgttttgtgg attgatgggg ttgtgttgtg ttgtgtttta 3600 gtgttttttt tgtttgttgg agttggttgt ggtttggttt gttttggttg tgggtgggag 3660 aggttgggtg aagttagtgt tgtggttttg tttttgtttt gtttagtttg tttatttttg 3720 gaattgtgtt tgtttgtttt gttgttttgg ggtgggaagt agaggtaaag ggagggtgtg 3780 tggttttttg tattttgttg tgtttttttt tgttttgttt tttagagttt tttatttatt 3840 ttgttttggt atttagtttt tggtttgtgt tattgtgtgt ttgttttgga tgttgtgggt 3900 ttggggatta gggtgttttt attgtggttt ttgttttttt ttggttgtgg tt 3952 <210> 46 <211> 2820 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 46 tttaggggat aatatttagg tatgttaatg gagtttaaaa tgttaaggaa attatattat 60 aattttgttt agtatattat aggttgttaa attgaaatgt tatgttagtt aggagtgtag 120 taatttttat tttttggttt tatttaatta ggaagtttta gtagagtgaa gtttgttaag 180 tgtttgttgt tagaatttga aggaatttga gtgagtaaga agagtgtttg atttatttta 240 tagaagtttg tttagaaatg gaggagttag tgtttattga agttggtttt gtttttggtt 300 tgtttatatg gagtttgatt agttttagtt atgtttattt tggtttggga gatttgtaaa 360 gtgttttttt ttttaatttt tttgtattat tttgaagttt agggaagtaa agagaggggt 420 atatttggat tgtaaaatta atgttttttg ttgtttagga gagaagggaa tgagagagag 480 agagagatag atagatagag agagagagag agagagagag agagagagag agagagagag 540 agaaatttta ttgaaattta gtttttttag aatttgtgtg atttggtttt taatgggaga 600 ttagtgtgat tttatggtat ttttgttagg aattagtgat ttttttgtag ttattatttg 660 atttattgtt tttttgttta ttttttttta taaagttatt ttttttttat tttagtaaga 720 tttttttttt taatgatgat aaagtttttg ttttagtgtt ttttttagga ttggtgtttt 780 tttaaaatag tgaatttaga aaattatttt gtttaatatt ttttaaaatt tttgtagttt 840 taatgtaagt gtaagtatgt aaaggttttt tgttatattt gtattttttg tttattttag 900 aattattttt tatttttggg tttgtaatag ttttttttgt ttttttggat agaggtgggt 960 ggtattaggg gtttagggta gtaggaggtg aggggttgag gaggttgtta gggtaggttg 1020 gtttgtgttg gatatgtgtg tttttttgtg gagttaaagg gttggggatg ggggttttgg 1080 atttattaga gtaattttag ttggtgggtg tttggtagtt atttaaggag gtagggaaag 1140 tagtgagttt tattgggtgg gttatgatga gtagtatgat gggtagtagt agtagttagt 1200 aaaagttttt gtaaagtgtt tagttgttgt attgttgtgg ggatttttat agtattatga 1260 ttagtttgtg taattttgta gtagtaaatg gtttttgagg aatataggat tgtgggggtt 1320 gggtagtggg ttattgagta ttttgtggat ggtggtagta gaggtggtgg tggtggtagt 1380 ggtatttggt ggggaagtag tagttaaatt tgtgtatgat tttgagagtt ttagtaatat 1440 ttagggattg ggtttagttt tggagtgaga gggttgtttg ttgagaagtt gtgttggaga 1500 tgtgggaagt tgttgttata aggagggagt tttgggaagt tggaggatag gaggagatgg 1560 gagtttaggg gtagatgagt ggagtttgag gaggtagggt ggagggagag ttaaggtgtt 1620 ttgtagtttg gtagttgttt tttgagtttt gttgtttgta tttttttggt gtttgggaag 1680 tagtaggttt ttagtttgtt tggggttatg tgggaagagg tagttgggtt ttgattggtg 1740 gagtaggatg taggttttgg gagggagggg ttgatgagga ggtgtaagga tgtaaggagg 1800 aggtggttgt ggaagttata gatgggtttg tttgttaggt gttggtttga gtggggttag 1860 gtggggatgg tttaaatgag aagtttgggt tttagggtgg gttatttgta tatttatata 1920 ttatttgttt tattttttgt tttaggatgt tttttattga aggtggggtt tggattagtg 1980 tttttttttt gtgtgtgatt ttgggttgtg agtgtgggtt gtggttgggt ggtgtttttt 2040 tgagttggag atggtggggg tggaggtgtt agaggagtag tagtagtagg gtagagaggg 2100 gtgagttggt gtgggagagg gtgttttgtt ggtgattggt gttttagtgt gtgggagtgt 2160 gttgtttagg ttgtaggggg atgtaggttg ggaatgttgt ggtggagagg ttagggatgt 2220 ttttttaggg atttatagga aagagggtga gaggtgatgg tgttagaatt gtttttgttg 2280 atttggaagt aatagtagta ttttttataa gagtgtgtaa ttttaaggtt gtttgttgag 2340 gtagtttagt tattttggta ggtgtttttt tttttttttt tttttttttt tttttttttt 2400 aggttttttg tagttttgat ttagtttaag tgtttgtagg tttgaatttt tttttttatt 2460 atttgttttt ttttagtttg tagtttatta gtgtgtttat ttgggaggtg tggttagatg 2520 tgtttggaag gttagattgg ttgggataag tggtttgaga gaaagagaaa ggtttttttg 2580 tatatgttgt gggtgggttg ttgggagtat tggttgggta gtggtgtttg ggaaggggag 2640 agtgggtttt atttgttggt ttaggtagtg attttgtgtt ttttatttgg gtttttgttg 2700 gatggttggt gatttggggt gatgagagaa ggtttaattt ggtaggagtt tttggttttg 2760 tgtgtttttt ttattttttt tagtgggaag ggtaaatggt atagtgggat ttgttttttg 2820 <210> 47 <211> 2820 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 47 tggaaggtgg gttttgttat gttgtttgtt ttttttgttg gagagaatga aagaaatgtg 60 tagagttaga gatttttgtt gagttagatt tttttttgtt gttttaggtt attggttatt 120 tggtaaagat ttgagtaagg aatgtagggt tattgtttgg gttaataaat ggagtttgtt 180 tttttttttt tggatgttgt tgtttggttg atgtttttgg taatttattt gtggtgtatg 240 tagaggagtt tttttttttt ttttagatta tttgttttga ttaatttgat tttttaaata 300 tatttgattg tattttttag gtggatatat taataggtta tgggttggag aggagtgggt 360 gatgaggaga gggatttaaa tttgtgaatg tttgggttgg gttggagttg tggggggttt 420 gggaggagag aggggagaag agagaaggaa ggagagtgtt tgttgggatg gttgagttgt 480 tttggtgagt agttttgggg ttgtatgttt ttgtgggaga tgttgttgtt gtttttaggt 540 tggtaagagt ggttttaata ttattgtttt ttattttttt ttttgtaaat ttttagagaa 600 atgtttttgg tttttttgtt gtgatatttt tagtttgtat ttttttatag tttaggtggt 660 gtgtttttgt atgttggagt gttggttgtt agtaggatgt ttttttttgt gttgatttgt 720 ttttttttgt tttgttgttg ttgttttttt gatatttttg tttttattat ttttagtttg 780 gagagatgtt atttagttgt ggtttgtatt tgtggtttgg ggttatgtgt ggaagagggg 840 tgttagtttg gattttgttt ttggtagggg gtgttttgga gtggagagtg aggtgaatgg 900 tatatgagtg tgtgggtagt ttattttgaa gtttgagttt tttatttgag ttatttttgt 960 ttagttttat ttgggttagt gtttggtgag tgagtttatt tgtggttttt gtggttgttt 1020 tttttttgta tttttgtatt tttttgttga tttttttttt ttgggatttg tattttgttt 1080 tattaattag agtttgattg ttttttttta tgtgattttg ggtgggttga ggatttgttg 1140 ttttttaaat gttagaggga tgtgggtggt agagtttgag aggtggttgt tgggttgtgg 1200 ggtgttttga tttttttttt attttgtttt tttgggtttt atttgtttgt ttttggattt 1260 ttgttttttt ttgttttttg gttttttaga gttttttttt tatggtagta gttttttgtg 1320 tttttggtgt agttttttag tggatgattt ttttgttttg gggttgagtt tagtttttgg 1380 atgttgttga aatttttgag attatgtgtg ggtttggttg ttgttttttt gttgggtgtt 1440 attgttattg ttgttgtttt tgttgttgtt gtttgtggga tgtttagtag tttgttgttt 1500 ggtttttgtg attttgtgtt ttttggaagt tgtttgttgt tgtagagttg tatgaattag 1560 ttatggtgtt gtgggagttt ttgtggtagt gtagtagttg gatattttgt gagggttttt 1620 gttggttgtt gttgttgttt gttatgttat ttattgtagt ttgtttggtg aagtttgttg 1680 ttttttttat ttttttaagt gattgttaaa tgtttattgg ttggaattgt tttggtaagt 1740 ttagaatttt tgtttttgat tttttaattt tgtagaagaa tatgtgtatt tagtatagat 1800 tagtttattt tagtggtttt tttagttttt tattttttat tgttttagat ttttaatatt 1860 atttattttt atttagagaa ataaggggaa ttgttgtagg tttgggggtg aggggtggtt 1920 ttgggatggg tagaaagtgt aggtgtagta ggaaattttt gtatgtttgt gtttatattg 1980 gagttgtgag gattttgaga aatattaaat gggatggttt tttgggttta ttgttttgaa 2040 agagtattaa ttttagggga aatattgaaa tagaagtttt gttattatta aagaaaaaag 2100 ttttattagg atgaggaaga aataatttta tgagaaagaa tgagtgagaa agtaataaat 2160 taaatggtga ttgtagggga attgttgatt tttggtaaag gtgttatgag gttgtattgg 2220 ttttttgttg aagattaggt tatatagatt ttagaggagt tgggttttaa tagaattttt 2280 tttttttttt tttttttttt tttttttttt tttttttttt ttttatttat ttattttttt 2340 ttttttttta tttttttttt ttttaggtgg taaaagatat tggttttgta gtttagatat 2400 gttttttttt ttgttttttt aagttttaag gtagtatagg ggagttgaga aaaagaatat 2460 tttgtgggtt ttttaggttg gagtgggtat gattgaggtt ggttaggttt tatgtaggtg 2520 agttgagggt ggaattgatt ttagtgggtg ttgatttttt tatttttgga taggtttttg 2580 tggagtgggt taggtatttt ttttgtttgt ttgggttttt ttagattttg atggtgaatg 2640 tttggtaggt tttgttttgt tgaagttttt taattaaata gggttagagg atgggagttg 2700 ttgtattttt agttggtata gtattttggt ttgatagttt gtagtatatt gggtagaatt 2760 gtggtgtaat ttttttggta ttttaaattt tgttaatatg tttgggtatt gttttttagg 2820 <210> 48 <211> 3104 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 48 gtgggtgttg ttgagtatgg ggaggtgttg aaatagtttt ggtgtgttga tttaagtttt 60 gattggtaga gttatttggt gattgatagg gggtttttat ggtgtttgtg ttgttaattt 120 gtttatttta atagtggagt tagtttgttt gttggtgtgt ttgagttgag ttgagtttga 180 attttaagtt gtggagttag tatttttttt agttggggtt gtttgttttt ggttgttgag 240 ttattgttgt tatttggtag tgtgttttgt tgttttaatt tgttttatta ataagtgttt 300 ggtatattta gttaggtttg tgggtatttg ttgtgtgttt tgttttgggt ttagtgtttt 360 tgttgttgtt ggtattgttt tgatgtttta gttgtttatt ttgaatttta gtttttagta 420 agtggttggg gtatgtgaga ttttggaaga gagtggtgat gtggagtgtt tgggttgttt 480 tttttggttg ttgtttgtgg tttttgtggt ttgtgaggtt tttaataaga atgagttggt 540 gttatgtgta tgagttattg tggtttttta tggtggtaat tattgtgagt tttattatat 600 tttggaaaat tataagttta ttaaggagtt gtatgttaag ttgtaggtgt tgtggtttga 660 agtatattat taggaggttg agaagttgtg tggaagattt ttgggatttg tggataagta 720 ttgagtaagg aagaagtttt tgttgttgtg tattatttgg gatggtgaat agaagatata 780 ttgttttaag gagtgtatgt ggtatttgtt atgtgagtgg tatttgtagg atttatattt 840 taattttagt aaaaaatgtg agtttgttta ggtaattgga ttgattttta tgtaggtggg 900 taattggttt aaaaattgtt gataaaggga ttgagtggtt gtagttaaga ataggttggt 960 atttagaggt ttttgtgttt tgagtgtatt ggggaggagg tgggtggagg tatttttggt 1020 gtttttattt agtttttggt gattttaatt tagtaggagt tgggagtgtg gtttgttttg 1080 ggttaagagt tttgtgtttt gggtttttgg ttgggagttt ttttgttggt tttgtttttt 1140 tatttgttgg ttttttatgt ttgtgggtag ttgtagtagt tggttttggt tattaaatta 1200 aggttttatt gggatggaga ggggaagaga aataaaaaat taaaatttta taaatagtta 1260 gggattttaa gatttaaagt taatttttgt tagtttgggt ataggttttt attattaatt 1320 gaagtttggt ttattagtaa tgtgttggtt ttatgttaat tattattttt aaagtttagg 1380 tatatttttt tttaatgttt tgaaaatagt ttttaatgga tttttgagaa atgggaagtt 1440 gagttttttt ttttttatgt gttgtttgtt atttttgttt taaaatagta aattagtttg 1500 tgggttgagg ttttttgttt tttggagtgt ggattttgat tagttaaata ttttgtggaa 1560 gagtttggtt ttatttttta ggtttaaatg ttttttataa ttttttttgt ttttaggttg 1620 ggttgatttg atttaatgtg attgtgggag tatttgttta ggtgtaagtt ttaggtagat 1680 gtattgttag aaatggtatt ttatgttttt gggattgatt tgtttttgtt atttatattt 1740 tgtttatttt ttgatagttt tgtaaatttt ttaaaagtgt ataataaata gggaggatat 1800 tgtaagttta gtatataaaa gatttgggag ttgtggtgtt gagaaagggt gtgaattatg 1860 gtggggtata atagtaggga tttgtggagg ggtggttgtg gatttttgtt tgatttttgt 1920 tgttttgttg agtaattttt gttttaattg ttggggtttt tggaagaatt tttagttgtt 1980 gggttggagg gatgtaggag gtggtggggg tgggtgatgg gtggttgtgt tatgagttgt 2040 gatttgtgtt tttttttttt tttgtagatt ttagtagtag gttttgttat agggttttgg 2100 gtgggtatta tgggtggagg gtgatggtat gttagaggtg ttgggtgttg ttattagttt 2160 ggttgttagt ttatttagta aggtggttat tttagttatt tttattatgt ttagtgatag 2220 tgagtgtgat atttgagttg tttatttagg atgtttagaa gtagatttta gtgtaaaaat 2280 gagaaaaata aaatgaaaga ggggaagaag atgagagatt tgtaaattta gtgttataga 2340 agttaggtga ttagggattt gtgggtttgg gttgttgttt tttgttttat tttgtggttg 2400 gtttggtttt attggtgttt tttggttgtg attatgggaa ttagtgtgag gtttgattta 2460 gtattatgtt ttttttgttt tgtttttttt taaggatttt gttgtaaagt ttttttggaa 2520 tttgaattgt aagttgagtg tttgtttaga tttttttatg ggtattttat gttgaaagga 2580 tgttgttata tatgtataat ttttgtttta aagttttttt ttaataaaat atatatatgt 2640 tgtttattta tttatttaag agattgttat ggtaggtttt tttgtagttt ggggaatttg 2700 ttgtttttaa atatgtaggt tggtggtgat gggttttgtg tggagaagtt aaataataaa 2760 ataatttagt gggtaatttt tttaattaag ggagttgttt ttagattttt ttttttttta 2820 ttattattaa tattattttt tttattaggt atgtagggat ttttgagtaa atggtttttg 2880 gaaggtttta tttatatatt ttttgttttt tttggtgttt tttggtatat gttttaaata 2940 atttatggta ggtttataat tattttttat gttaaattat atgtatgtgt atatatgtat 3000 gtatttatat aaatatatgt atgtatttat ataaatatat gtatgtatgt atatatgtga 3060 tatatttaag gttagaaatt ggtaatatgt gagtgttttt ttta 3104 <210> 49 <211> 3104 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 49 tagagaggat gtttatatgt tgttaatttt tagttttaaa tatattatgt gtatgtatat 60 atatatatgt ttgtataggt atatatatat gtttgtatag gtatatatat atatgtatat 120 atgtgtaatt tgatgtggga ggtggttata gatttattat aggttgttta aaatatatat 180 taggaagtat taaagaaggt aaaagatata taggtaagat tttttggaga ttatttgttt 240 aagggttttt gtatgtttgg tgaagggaat gatattaata ataataagaa gaaaaggaat 300 ttgagagtag tttttttaat taagaaggtt gtttattagg ttgttttatt gtttggtttt 360 tttatataga atttattatt attagtttgt atgtttagaa atagtaagtt ttttaagtta 420 tagagaaatt tattatggtg gttttttaaa taagtaaata aatagtatat atatgttttg 480 ttaaaaaaaa attttaaagt gaaagttata tatatgtaat agtgtttttt tgatgtgaaa 540 tatttatggg agaatttggg taggtgttta gtttgtagtt tgggttttga agagattttg 600 tagtaaaatt tttaggaaaa agtaaagtaa gaagaatgtg gtgttgggtt aggttttatg 660 ttggtttttg tggttgtggt taaagggtgt tagtgaagtt aggttggttg tggggtgggg 720 tgggaaatgg taatttgagt ttgtgggttt ttggttattt ggtttttgtg gtgttggatt 780 tgtaggtttt ttattttttt tttttttttt attttgtttt ttttgttttt atattggaat 840 ttgtttttga gtattttgga tgggtaattt agatgttgta tttgttgttg ttggatgtga 900 tggagatggt tgaagtggtt gttttgttgg atagattggt ggttgggttg gtggtgatgt 960 ttagtatttt tggtgtgttg ttgttttttg tttgtagtgt ttgtttggaa ttttgtgata 1020 ggatttgttg ttggagttta tggggaagaa agggaatatg ggttatagtt tgtaatatag 1080 ttgtttgttg tttgttttta ttattttttg tgttttttta gtttggtggt tagaggtttt 1140 tttgaagatt ttagtagtta aggtgaggat tatttggtaa ggtgatagag gttgggtagg 1200 agtttgtggt tgtttttttg tgggttttta ttgttgtgtt ttattatgat ttgtgttttt 1260 ttttagtgtt gtagttttta ggttttttat atattgggtt tgtagtgttt tttttgtttg 1320 ttgtgtattt ttgggagatt tataggattg ttaggaaata aatgaagtgt gggtgataag 1380 gatagattgg ttttagggat atgggatatt atttttaatg gtgtgtttgt ttggggttta 1440 tgtttgagta agtgtttttg tgattgtgtt ggattgggtt ggtttgattt aaaggtaaaa 1500 aggattgtaa ggagtatttg ggtttggggg atgaggttgg gtttttttgt aaaatgtttg 1560 gttaattgag atttatattt tgggaaatga aaagttttgg tttatggatt agtttgttgt 1620 tttgagataa gagtggtagg tagtgtatgg gaagaggaaa atttgatttt ttatttttta 1680 aaagtttatt gaaaattgtt tttaaagtat tagggaggga tatatttggg ttttgaaaat 1740 gataattaat atgaaattga tatattgtta ataagttagg ttttgattaa tagtaggagt 1800 ttgtgtttag gttgataaga attagttttg ggttttgggg tttttaattg tttgtaggat 1860 tttaattttt tatttttttt tttttttttg ttttagtgaa gttttggttt ggtgattggg 1920 attagttgtt gtagttgttt gtaggtgtgg ggagttagtg ggtggggaag tagagttggt 1980 aagggaattt ttggttagga gtttagaatg tagggttttt aatttaagat agattgtgtt 2040 tttaattttt gttgaattgg agttgttagg gattgggtaa gggtgttaga ggtgttttta 2100 tttgtttttt ttttggtgtg tttaaagtgt ggaggttttt aggtattgat ttgtttttgg 2160 ttgtagttgt ttggtttttt tgttggtggt ttttgaatta gttgtttatt tgtgtagggg 2220 ttagtttggt tgtttgggtg agtttatgtt ttttgttggg gttagggtat ggattttgta 2280 ggtattattt gtgtagtagg tgttgtgtgt gttttttgaa gtagtgtgtt ttttgtttgt 2340 tgttttaaat ggtgtgtggt agtgggaatt ttttttttat ttggtatttg tttataggtt 2400 ttaggggttt tttatgtagt tttttagttt tttggtagtg tgttttaagt tatagtgttt 2460 gtagtttggt gtgtgatttt ttggtgaatt tgtggttttt taggatatga tagagtttgt 2520 ggtagttgtt attgtgaaag gttatgatgg tttgtgtgtg tagtattgat ttatttttgt 2580 tgagggtttt gtaggttgta ggggttatgg gtagtgatta gaggaagtga tttaggtgtt 2640 ttatattgtt gttttttttt agggttttat atattttggt tatttgttgg gggttgaaat 2700 ttaagatggg tagttggaat attgaggtag tgttggtggt ggtgagggta ttgagtttgg 2760 agtgggatat gtagtagatg tttgtgggtt tggttgagtg tgttaggtgt ttgttgatga 2820 ggtggattgg ggtagtggga tatattattg ggtggtggtg gtggtttaat ggttgggagt 2880 ggatgatttt gattggagga ggtgttggtt ttgtggtttg gggtttgggt ttggtttggt 2940 ttaggtatgt tggtaggtga gttggttttg ttattggggt gggtggattg gtggtgtggg 3000 tgttatggag attttttgtt agttattggg tggttttgtt aattaaagtt tgaattagta 3060 tgttaggatt attttagtat ttttttgtgt ttgatagtgt ttgt 3104 <210> 50 <211> 2378 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 50 attttgagat tttagttgat tttttttgtt ttgtaattag aggggattgt gatttgggtt 60 aatttttttt ttatgggttt tagtggagtt agttgtggaa tggaatatta atttttattt 120 tataggtatg ttgtgaggtt ttgttaagaa atagttataa aagggtttta agagttatga 180 tgattgtttt aattatttag tagggagggg gtatttagtg gtgttgtttt tatgtattga 240 tgttatgtgg ggtggggagg tggggtggag aatggagagt gtttttttat tttttatttt 300 ttttttttaa gtttagtgta gggggaggtg gttgtgattg attgaggggt tagggaaggt 360 tggttagggg tgtgggtgtg gttggggatg gtttgggggt ggggttgtgt aggaggttgg 420 aggagttttg tgggatttag aggtggggtg ttggtttggg gattattgtt tttttggggt 480 gtggttgtag gaggttggag gagttttgtg ggatttagag gtggggtgtt ggttggggat 540 tgttgttttt ttggggtgtg gttgttgttg agtatttttt agtttagttg agtttgtgtt 600 taggttatgt tttgttttag ttgttgtttt ttttatttta tggtgtttgg agttattttt 660 tgtttgtttg tttttttttt ttgtttattt tttgtatttg ggtttgtatt atttttgtta 720 attgtttttt tgattttgtt gatatttttt ttttaaattt ttgattggta tttttgtttg 780 gtattttttt ttttattttt ttttttttat tttttttttt tgattttttt tgggtttttt 840 tttttttaaa atttgggttt ttttgtgtgg ttttgttttt aggttgggga tgttttttgt 900 ggttttgtgt ttatggtttt gatgttgttt ttttttgttt ataagttgtg ttgttttttt 960 gttatgttgg gtttatggtg gggtgttgag tggttggtgg tgtttgggtt agatgggggt 1020 ggtggtatgg gtttatggtg ggttgtgggt ggtttgggtt tgtgaaagtg ttgttggggg 1080 taggtattga ggtgtaggat gttttggagt gtgtgttgtt ggagttgtag taggttttgt 1140 ttgtgttgaa gtaggtgggt ggtgtgtggg ttgtgggtgt tggtttggtt gaggtttttt 1200 aattggtgga ggaggtttgg ttgttgtggt tgtgggttgt gaggtagttt agggtttgtg 1260 tgatgttatt tgttttgatg gtggttttga tttgttgttg tggttgttgt aggtgttgga 1320 gttggagatg tgtgtgtagg ttgtgtgttt gttggagtag attttggtgg ttgagaattg 1380 gtgagtgtgt taggttgggg ttgggagagt gttgtgtggt gtggatagtt aagtgtttgt 1440 gtttttgtgt gttttgtgtt gtgtttttgt tttttttatt tttttgattg tttgtattat 1500 atttttgtta ggggttagtt tgtttgtttt atagataagg aaattgagtt ttgggaaagt 1560 ttagtgattt gtttagtgga ttatagtgaa ttaagatttg tttttagggt tagtggggtg 1620 aggaatggag ttataggata ggagtttgtt tttggtttta tggatggaga tggtatttta 1680 ttgttaattt tttttttttt ttgtttttta agtttatagt tttttttttt attggtttgg 1740 gtttttgttt atgatatttt tttttgttat tattttattt tttttttaat gagagaagaa 1800 gggaaatata atgtttagaa aagagggagg gagatttttt tttttttttt tttttaggtt 1860 gtaaggtgtg ttggtttgag gttgtttatt ttttttttgt tgttttaatt taatttttgt 1920 tttatttttt attttggttt ttgtaatagg ttagatatga ttttattttg tagttgttga 1980 tgggaaatag ttttttgttg ggaggtatgg gtgggggaag aggatattgg ggtgtagagt 2040 ttggtgggga ttaggtagag tgtgtgtttt ttttttttat tttatttagt attaagatgt 2100 tgtaagaggg ttaaatagag gtttggttgt tatttttgta tgttttttgg gatttttttt 2160 ggagtatgaa gatttttaag gatttatttt tttttttttt tgatgttaga gtagattaag 2220 ttgttatatt ttagttttat gttgaagttt ttagtttttt aagtttagaa gagtttttgg 2280 aagagttatt tttagtttat gtagttttta taagtgtgaa gggagtgggt tgggggtgtt 2340 ttttttgtta tttttgaaaa gaaaaaaatt atttggtg 2378 <210> 51 <211> 2378 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 51 tattaggtaa tttttttttt tttgaaaatg gtaaggaaaa tatttttaat ttattttttt 60 tatatttgtg agagttgtat gagttgaaag tgattttttt aaaaattttt ttaagtttga 120 gaagttggag attttagtat gagattggag tgtgatagtt tggtttgttt tggtattaga 180 agggagggaa agtgagtttt tggaggtttt tatattttag gagagatttt aagagatatg 240 taagagtggt aattaggttt ttgtttgatt tttttgtggt attttggtgt taagtggggt 300 gaagggagag aatatatatt ttgtttggtt tttgttgggt tttgtatttt ggtgtttttt 360 ttttttattt atgtttttta gtagaaaatt gttttttatt agtagttgta gaatgagatt 420 atgtttggtt tgttgtaaga attagaatga aggatggagt agaagttgga ttggggtggt 480 aagaagggag taagtagttt taggttagta tgttttatag tttggggagg agggaaagga 540 gaggtttttt tttttttttt ttgagtgttg tgtttttttt ttttttttat tgggagaggg 600 atgggatgat ggtgagagaa ggtgttatag atgggaattt aagttggtgg gaaggagagt 660 tgtgggtttg gggggtgggg gagagggaga attggtaata ggatgttatt tttatttata 720 gagttaggga tggatttttg ttttgtaatt ttatttttta ttttattagt tttgggagta 780 aattttagtt tattgtgatt tattgagtaa gttattaaat ttttttaagg tttagttttt 840 ttatttgtga aatagatagg ttgattttta atagagatgt agtgtaggta gttagagagg 900 tgagggaggt aaaggtatgg tgtaaggtat atgggaatgt aggtgtttaa ttgtttatat 960 tatgtggtgt ttttttaatt ttggtttggt gtgtttattg gtttttagtt attaggattt 1020 gttttagtag gtgtgtggtt tgtatatgtg tttttaattt tggtgtttgt agtagttgta 1080 atagtaggtt gaggttgtta ttgaggtgga tggtgttgta tagattttgg gttattttgt 1140 ggtttatggt tgtagtagtt aggttttttt tattagttgg aagattttgg ttaggttggt 1200 gtttatggtt tgtgtgttgt ttgtttgttt tagtgtggat aaggtttgtt gtagttttgg 1260 tagtgtgtgt tttagggtgt tttgtatttt ggtgtttgtt tttggtgata tttttgtggg 1320 tttgggttat ttgtagttta ttatgggttt gtgttattgt ttttatttgg tttaggtatt 1380 gttagttgtt tggtgttttg ttgtgggttt gatatggtga agaagtgata tagtttgtag 1440 gtggagagaa gtagtgttag gattatgggt gtggggttgt gggggatatt tttggtttgg 1500 aggtggggtt atgtggagag atttgggttt tgggaaaaga gggatttgag aggggttggg 1560 gaaagaagat ggagggggag gaatggagag aagggtatta ggtaagggtg ttggttagaa 1620 gtttggggga ggagtgttgg taggattggg ggagtggttg gtaaaggtga tgtaggttta 1680 gatgtaggga gtgggtgaaa ggagagagtg agtaggtgag ggatggtttt ggatgttgta 1740 gggtagagga ggtggtggtt ggaataaagt gtggtttggg tatgggtttg gttgagttgg 1800 gagatgtttg gtagtagtta tgttttggag gagtagtggt ttttggttga tgttttgttt 1860 ttgggttttg tggggttttt ttagtttttt gtagttatgt tttggaggag tagtggtttt 1920 tgggttgatg ttttgttttt gggttttgtg gggttttttt agttttttgt gtagttttat 1980 ttttaagttg tttttagtta tgtttatgtt tttggttagt tttttttagt tttttagtta 2040 gttgtagtta tttttttttg tgttggattt ggaggaaggg ggtggagaat gagaggatgt 2100 tttttgtttt ttgttttgtt tttttgtttt atgtgatatt ggtatgtggg agtaatattg 2160 ttggatgttt tttttttatt aaatggttaa aataattatt ataattttta aggttttttt 2220 atggttgttt tttagtgaaa ttttataata tgtttatggg gtgggaattg atgttttatt 2280 ttatagttga ttttattgaa gtttatgagg aagaaattgg tttaaattat agtttttttt 2340 gattatagaa tagaaaaagt tagttaaaat tttaggat 2378 <210> 52 <211> 2436 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 52 agttttggat gataaggatt aattgtttag ggtgttggtt gagaggaata ggaagagtgt 60 tttgtggagt agggtgggtg agaagagttg ggtggttgtg gggtttttgt gtatgttggg 120 taggaagagg aagagttgta gtatgaaggt tattagggag atgtataaga agtaggtggg 180 ggttattatg ttgagtagtt gtagggttag tatttttgat tatatttttg tggggtttgg 240 ggtgagaaga ggattgattg attatggtgt ttagggggtg tttttgtttg tttttttgtg 300 ttgtgtgttt ggggtattgt atgtgatttt atgtttttaa ttttttgttt tgtggatttt 360 ttttttttag ttttttaatt ttggattagg taggttagag atttgagttt gtagtggttt 420 tgggtttagg ttttatttgg gggtgagtgt tgtttggggt tttgagtgag tttggtgttt 480 tggtgtggta gagtttggta taggagggag ggatttgttt gtagttttta ggagttgtga 540 gggtgggggg tattggggga taggattttt tttttttgtg gatgtggaaa taagtttagg 600 tttgggattt ttggtttaga tttttttagg aggagaaagg gaaggatttg gggttggggg 660 taggagaatt agtggtattt gatttgttgg aaattttgtt ttatattttt ttttttttgt 720 ttttgtgttt ttatttatat atatattttg ggtagtattt agggatttta ttaggttatt 780 taaggttttt tggaggtatg tgtgtgtgag ggattatgat gtgtgtgtgt gtgtttttgt 840 ttgtgatttt gtatgtgtaa tttgtgtgtg tttgagtatt tgtatttgtg tatgtatata 900 tttgtgtgta tagatatgta gtttttgtta tttagtttta aaaaaattaa ttgaaataat 960 tgatatattt atatttgttt ttgggtattg ggtgaggtgg gggtgtaatt agaatatttg 1020 tgttagtggg ttttggttag tatatttttt taatgttggt tgtttgggtt atttttttgt 1080 gaagagtgtt tttatttgag gtgaaattaa aatttttttt ttgtgtttgt tttttgtttt 1140 tttgttgaga gaaatttaaa taatttttat ggtgttgaaa ttttttttat gttgataagt 1200 ttgttttggg tgtatgagtg gatgtttggt tagttttttt tgggattgat tttgttgttg 1260 tgtttagttt ttattatgtt tttattttat tttatgtttt atagttgggg tttttggtta 1320 gttttggaag ttattgagaa ataggatttt gtgtgtttga gagaattttt ttaggggtta 1380 aggaattggt tagttggagg tgtgagaaaa gttttgggaa ggtggttgta tttaggatgg 1440 gtggatgtta tggggttttt gtttaggttg ttttgtttgt atgggttgat tggttatttt 1500 ggaatttttt ttgtaggttt tagtgttttt tgggaatttg tagtttttgt ggagagtgtg 1560 ggtttttttt tattgttggg gtgtagtgta gtgtatgttt gagggtggtt gttgggggtt 1620 gggtatgttt ttagttttgt gttgttgggg gttgtggtgg tgttgtttat tttagagagt 1680 ttttggtttg gggttttggt gaagtaagtg tttttttggt gttggttgtt aggggggtgt 1740 gggagtagtt agatgtgttg tagtgttggg aaggtggtga aggatagggg ttaggggagt 1800 gaggggtgtt tggtaggtag ttttagtttt ggttttgtgt gggagaaggg atagtagaga 1860 ttgtttgtgg ggttttgggg tgtagggagt tgtttgttta gttttggtgt ttgttttgtt 1920 tgtggtagag ggtggtatag ttggagtttt ggaaagattg gtagtgttgg tagttgtggg 1980 ttttttggtt attgtttttt ggatgtatgg gaagttgttt tttgtgttgt tgttgttgta 2040 ttgttgttgt tgtagagggg tgaggaaatt aatttattga gttttggttg ttgataagag 2100 gagttttgga tgttggtttt tgttttgttt gaggttgtaa agttgtggat ttggtttggt 2160 tggtttgtag tttgtgtttt gttttgggaa ttgggtaagt agtggggatg tggggaggag 2220 ggagtgggta gttgttggtt ttttatttgg gtgttagtga gtaagggtta ggaagtggtg 2280 gggatggtag ttgggtattt tttagttttg ttattttttt ttttgttttt gggggtggtg 2340 ttttggttgt tagttttagt attgtggatt tgtttttttt tttttttttg attttttttg 2400 agtgggttgg ggtgttttgt ttggttttag tgtttg 2436 <210> 53 <211> 2436 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 53 tgggtgttga aattaggtag ggtgttttag tttgtttaag gggaattgag aggggaggag 60 ggggtaagtt tatgatgttg agattggtgg ttagagtatt gtttttagga gtggagggag 120 gggtggtggg gttggggggt gtttagttgt tatttttgtt gttttttggt ttttatttgt 180 tggtgtttaa gtgggaagtt agtagttgtt tgtttttttt tttttatatt tttgttattt 240 gtttagtttt tgaagtgaag tgtaggttgt gagttagttg ggttgagttt ataattttgt 300 agttttgggt agggtgagag ttggtgtttg gggttttttt tgttggtgat tagagtttgg 360 tgagttgatt tttttatttt tttgtgatgg tggtagtgtg gtggtggtgg tgtggggggt 420 ggttttttgt gtgtttggga ggtagtggtt gagaagtttg tggttgttgg tgttgttggt 480 ttttttaagg ttttggttgt gttgtttttt gttgtgggtg aggtgggtgt tagggttgaa 540 tggatagttt tttatatttt ggggttttat gggtggtttt tgttgttttt ttttttgtgt 600 agggttaggg ttgaggttgt ttgttgagtg ttttttattt ttttagtttt tgttttttgt 660 tgttttttta gtgttgtggt gtatttggtt gtttttgtgt ttttttggtg attggtgttg 720 ggaaggtatt tgttttgttg gagttttagg ttgagggttt tttggggtgg gtagtattgt 780 tgtagttttt ggtggtgtag gattgggggt gtgtttagtt tttggtgatt atttttaggt 840 gtgtattgtg ttgtgtttta gtggtaggga gaggtttatg ttttttgtgg aggttgtggg 900 tttttggggg gtgttgggat ttgtaaaggg gattttaagg tgattagttg atttgtgtgg 960 atgggatagt ttggatggag gttttgtggt atttatttat tttaggtgta attgtttttt 1020 tagaattttt tttgtgtttt tggttggttg attttttagt ttttggaaaa gtttttttgg 1080 gtgtatggaa ttttattttt tggtggtttt tgaagttggt taggaatttt ggttgtgagg 1140 tgtggggtgg gatggggatg tggtgagggt tgagtatggt ggtggggttg attttaggaa 1200 aggttggtta agtatttatt tgtgtgttta gggtgggttt gttggtatgg aaaggatttt 1260 ggtgttatga gggttgtttg ggtttttttt agtaggaggg tgggaggtgg gtgtgaaggg 1320 gggattttaa ttttgtttta aatgaaaatg ttttttgtaa agaaatagtt tgggtagtta 1380 gtgttggaga gatgtgttgg ttaggatttg ttgatatagg tattttggtt gtgtttttat 1440 tttatttggt gtttgagagt gagtgtgagt gtattgattg ttttaattga tttttttaaa 1500 gttagatagt agaggttgtg tgtttgtata tgtagatata tatatatata aatatagata 1560 tttaagtgta tatagattat atgtatagag ttatagataa ggatatatat atatatattg 1620 tggtttttta tgtatatata tttttaaaga gttttgggta atttggtgag gtttttgagt 1680 gttgtttaag atgtgtgtgt gggtggggat gtagggatgg agaaagggga gtgtgaagta 1740 ggatttttag taggttaagt gttgttgatt tttttgtttt tgattttaaa tttttttttt 1800 ttttttttta gggaggtttg aattagaaat tttaaatttg ggtttgtttt tatatttata 1860 gaggggagga gttttatttt ttggtgtttt ttatttttat aatttttaaa gattgtaaat 1920 gagttttttt tttttgtgtt agattttgtt gtgttaaggt gttgagtttg tttaaaattt 1980 taggtaatat ttatttttag gtggggttta gatttgaggt tgttgtgggt ttgggttttt 2040 ggtttgtttg atttggggtt agggaattgg ggaggggaaa tttgtgggat agggggttgg 2100 gggtgtggag ttgtgtgtag tgttttagat gtgtggtatg gaggagtggg tgagggtgtt 2160 ttttggatgt tgtagttagt tagttttttt tttattttgg gttttgtagg aatgtaattg 2220 aggatgttgg ttttgtggtt gtttaatgtg gtggtttttg tttatttttt gtgtattttt 2280 ttggtgattt ttgtgttgta gttttttttt tttttgttta gtatgtgtga ggattttgtg 2340 gttgtttggt tttttttgtt tgttttgttt tatggggtgt tttttttatt ttttttggtt 2400 aatgttttgg gtaattagtt tttgttattt agaatt 2436 <210> 54 <211> 32 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 54 catcatatca aaccccacaa tcaacacaca ac 32 <210> 55 <211> 25 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 55 gttcgaaatg attttattta gttgc 25 <210> 56 <211> 17 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 56 cgttgatcgc ggggttc 17 <210> 57 <211> 17 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 57 ggggagggtt gtttatt 17 <210> 58 <211> 17 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 58 cccctccctt taactct 17 <210> 59 <211> 31 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 59 ttaactctcc ccaacaactc tcaaacccca c 31 <210> 60 <211> 24 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 60 ttagtcggag gtgaggaacg attt 24 <210> 61 <211> 24 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 61 ttatttcgtt gtcgggttta agcg 24 <210> 62 <211> 20 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 62 ggagtggagg aaattgagat 20 <210> 63 <211> 22 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 63 ccacacaaca aatactcaaa ac 22 <210> 64 <211> 33 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 64 tgggtgtttg taatttttgt tttgtgttag gtt 33 <210> 65 <211> 22 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 65 gtagtagtag tagggtagag ag 22 <210> 66 <211> 19 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 66 catcccccta caacctaaa 19 <210> 67 <211> 35 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 67 caacctaaac aacacactcc cacacactaa aacac 35 <210> 68 <211> 16 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 68 cgcgggagag ggcgtt 16 <210> 69 <211> 19 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 69 tgttggcgat cggcgtttt 19 <210> 70 <211> 16 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 70 gggtttcggg cgggta 16 <210> 71 <211> 21 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 71 atatcgcact cgctatcgct a 21 <210> 72 <211> 23 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 72 gagggcgacg gtacgttaga ggt 23 <210> 73 <211> 24 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 73 ttgggcgtcg ttattagttc ggtc 24 <210> 74 <211> 19 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 74 gtcgggttgg agggacgta 19 <210> 75 <211> 21 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 75 atatcgcact cgctatcgct a 21 <210> 76 <211> 23 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 76 gagggcgacg gtacgttaga ggt 23 <210> 77 <211> 24 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 77 ttgggcgtcg ttattagttc ggtc 24 <210> 78 <211> 21 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 78 gaggtgttag aggagtagta g 21 <210> 79 <211> 17 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 79 tccccctaca acctaaa 17 <210> 80 <211> 37 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 80 acctaaacaa cacactccca cacactaaaa caccaat 37 <210> 81 <211> 15 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 81 cgagtcggcg cggga 15 <210> 82 <211> 20 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 82 agggcgtttt gttggcgatc 20 <210> 83 <211> 25 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 83 aaaaaaaaaa aactcctcta catac 25 <210> 84 <211> 24 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 84 ggttattgtt tgggttaata aatg 24 <210> 85 <211> 38 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 85 acatacacca caaataaatt accaaaaaca tcaaccaa 38 <210> 86 <211> 21 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 86 tttttttttt cggacgtcgt t 21 <210> 87 <211> 20 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 87 tcggtcgatg ttttcggtaa 20 <210> 88 <211> 20 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 88 tgagagagag agggttgaaa 20 <210> 89 <211> 24 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 89 tctaaataac aaaatacctc catt 24 <210> 90 <211> 27 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 90 ccattaccaa cacaacccac caaccaa 27 <210> 91 <211> 16 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 91 cgacccgcca accgac 16 <210> 92 <211> 15 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 92 cgccgaaacg cgctc 15 <210> 93 <211> 26 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 93 gtagtagtta gtttagtatt tatttt 26 <210> 94 <211> 17 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 94 cccaccaacc atcatat 17 <210> 95 <211> 32 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 95 catcatatca aaccccacaa tcaacacaca ac 32 <210> 96 <211> 19 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 96 gaaccccgcg atcaacgcg 19 <210> 97 <211> 26 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 97 gtagtagtta gtttagtatt tatttt 26 <210> 98 <211> 17 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 98 cccaccaacc atcatat 17 <210> 99 <211> 32 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 99 catcatatca aaccccacaa tcaacacaca ac 32 <210> 100 <211> 25 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 100 gttcgaaatg attttattta gttgc 25 <210> 101 <211> 17 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 101 cgttgatcgc ggggttc 17 <210> 102 <211> 20 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 102 ccaaaaccta aacttacaac 20 <210> 103 <211> 17 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 103 ggaaatttga ggggtaa 17 <210> 104 <211> 31 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 104 tacaacacca ccaacaaacc caaaaacaca a 31 <210> 105 <211> 19 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 105 gttaattgcg ggcgatcga 19 <210> 106 <211> 17 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 106 cgtcgttagc gggtggg 17 <210> 107 <211> 20 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 107 aaaatcctct ccaacacgtc 20 <210> 108 <211> 20 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 108 cgcgattcgt tgtttattag 20 <210> 109 <211> 25 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 109 cggatttcgc ggttaacgcg tagtt 25 <210> 110 <211> 24 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 110 tctaaataac aaaatacctc catt 24 <210> 111 <211> 25 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 111 gtttttttta ttagttggaa gattt 25 <210> 112 <211> 20 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 112 aaactacaac aaaccttatc 20 <210> 113 <211> 37 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 113 ccttatccac actaaaacaa acaaacaaca cacaaac 37 <210> 114 <211> 17 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 114 cgtttacggt tcgcgcg 17 <210> 115 <211> 20 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 115 cgttcgtttg ttttagcgcg 20 <210> 116 <211> 23 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 116 ggtgttgttt attttagaga gtt 23 <210> 117 <211> 17 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 117 ctcccctaac ccctatc 17 <210> 118 <211> 29 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 118 ctatccttca ccaccttccc aacactaca 29 <210> 119 <211> 16 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 119 ttaggggggc gcggga 16 <210> 120 <211> 21 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 120 gttagatgcg tcgtagcgtt g 21 <210> 121 <211> 20 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 121 aaaatcctct ccaacacgtc 20 <210> 122 <211> 20 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 122 cgcgattcgt tgtttattag 20 <210> 123 <211> 25 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 123 cggatttcgc ggttaacgcg tagtt 25 <210> 124 <211> 20 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 124 aaaatcctct ccaacacgtc 20 <210> 125 <211> 20 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 125 cgcgattcgt tgtttattag 20 <210> 126 <211> 25 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 126 cggatttcgc ggttaacgcg tagtt 25 <210> 127 <211> 26 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 127 gtagtagtta gtttagtatt tatttt 26 <210> 128 <211> 17 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 128 cccaccaacc atcatat 17 <210> 129 <211> 493 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 129 ccttctccag ggctcaccca ggagggtgca gcggtggccc ccggggcggt ggtcgtggtg 60 ggggtgttag ctgcaggggt gccctcggtg ggtgggagtt ggtggcctct cgctggtgcc 120 atgggactcg catgttcgcc ctgcgcccct cggctcttga gcccacaggc cgggatcctg 180 cctgccagcc gcgtgcgctg ccgtttaacc cttgcaggcg cagagcgcgc ggcggcggtg 240 acagagaact ttgtttggct gcccaaatac agcctcctgc agaaggaccc tgcgcccggg 300 gaaggggagg aatctcttcc cctctgggcg cccgccctcc tcgccatggc ccggcctcca 360 catccgccca catctggccg cagcggggcg cccgggggga ggggctgagg ccgcgtctct 420 cgccgtcccc tgggcgcggg ccaggcgggg aggagggggg cgctccggtc gtgtgcccag 480 gactgtcccc cag 493 <210> 130 <211> 21 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 130 ccttctccaa aactcaccca a 21 <210> 131 <211> 22 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 131 ttgggggata gttttgggta ta 22 <210> 132 <211> 427 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 132 tgtgcccagg actgtccccc agcggccact cgggccccag ccccccaggc ctggccttga 60 caggcgggcg gagcagccag tgcgagacag ggaggccggt gcgggtgcgg gaacctgatc 120 cgcccgggag gcgggggcgg ggcgggggcg cagcgcgcgg ggaggggccg gcgcccgcct 180 tcctccccca ttcattcagc tgagccaggg ggcctagggg ctcctccggc ggctagctct 240 gcactgcagg agcgcgggcg cggcgcccca gccagcgcgc agggcccggg ccccgccggg 300 ggcgcttcct cgccgctgcc ctccgcgcga cccgctgccc accagccatc atgtcggacc 360 ccgcggtcaa cgcgcagctg gatgggatca tttcggactt cgaaggtggg tgctgggctg 420 gctgctg 427 <210> 133 <211> 22 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 133 tatacccaaa actatccccc aa 22 <210> 134 <211> 26 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 134 gtagtagtta gtttagtatt tatttt 26 <210> 135 <211> 556 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 135 gctagctctg cactgcagga gcgcgggcgc ggcgccccag ccagcgcgca gggcccgggc 60 cccgccgggg gcgcttcctc gccgctgccc tccgcgcgac ccgctgccca ccagccatca 120 tgtcggaccc cgcggtcaac gcgcagctgg atgggatcat ttcggacttc gaaggtgggt 180 gctgggctgg ctgctgcggc cgcggacgtg ctggagagga ccctgcgggt gggcctggcg 240 cgggacgggg gtgcgctgag gggagacggg agtgcgctga ggggagacgg gacccctaat 300 ccaggcgccc tcccgctgag agcgccgcgc gcccccggcc ccgtgcccgc gccgcctacg 360 tgggggaccc tgttaggggc acccgcgtag accctgcgcg ccctcacagg accctgtgct 420 cgttctgcgc actgccgcct gggtttcctt ccttttattg ttgtttgtgt ttgccaagcg 480 acagcgacct cctcgagggc tcgcgaggct gcctcggaac tctccaggac gcacagtttc 540 actctgggaa atccat 556 <210> 136 <211> 21 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 136 ggttagtttt gtattgtagg a 21 <210> 137 <211> 25 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 137 ataaatttcc caaaataaaa ctata 25 <210> 138 <211> 555 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 138 cacagtttca ctctgggaaa tccatcggtc ccctcccttt ggctctcccc ggcggctctc 60 gggccccgct tggacccggc aacgggatag ggaggtcgtt cctcacctcc gactgagtgg 120 acagccgcgt cctgctcggg tggacagccc tcccctcccc cacgccagtt tcggggccgc 180 caagttgtgc agcccgtggg ccgggagcac cgaacggaca cagcccaggt cgtggcaggg 240 tctagagtgg gatgtcccat ggcccccatc caggcctggg gatatcctca tccgcctccc 300 agaatcgggc cgtgggggac agaaggggcc tgcgtgcggg cagggagagt attttggctc 360 tctcctgtct tcggggttta caaagtgtgt tgggacttgc ggggctgctc tgtccaagcc 420 tgggtctggc gtccgcgtct ctgagcctgt gagtgcgtgc gctttcctgc gtcctcttga 480 ctgccggtgc tggggctctg cgtcctgcgt ccgcgggagt aaatacagca ggcgaagggg 540 aagctcacac aatgg 555 <210> 139 <211> 24 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 139 gtatagtttt attttgggaa attt 24 <210> 140 <211> 21 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 140 ccattatata aacttcccct t 21 <210> 141 <211> 529 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 141 tgcaagtttt gcatcctctc accactgcct gcgttacccg agttgtaaag ggcggctccc 60 tgtgtctgcc ccgctgcacc gatacaccga gctgcgcacg gtgcccagcg cagggagaac 120 aaatgatcat ctgtccaacg cgcccattta caggtgagga aactaaggct ccaactcaat 180 cgacgcactc tgcccttttg attaccagaa aagtagcagg acaggtgtcc tgtcccgccc 240 taccccggcc cactaagccg gcaccccggc tccgaccccc ggctgtgccc ggcgccgccg 300 cggtgcccgg cgccgccgcc tcgcccggcg gggccgcccg gagcgcccgc acctccgccc 360 gcttccacct ggccgggccc gccccgcccg gactcgggac tgggaagtgc ggcgactccc 420 ggaaccagcc attggcgcca gcgcggggag ctgggggtgc agagctgcgg gcgcggcggg 480 ccacgcaggc ggcccccacc cccggcctgg cctggtctgg tctggtctg 529 <210> 142 <211> 28 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 142 tgtaagtttt gtattttttt attattgt 28 <210> 143 <211> 23 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 143 caaaccaaac caaaccaaac caa 23 <210> 144 <211> 550 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 144 gcctggcctg gtctggtctg gtctgcgctg ccgcgcgggg gcgccccctc ccaggcccgg 60 cgcccgccag ccccgctccg ccaggtgcag cgcagcgcag gggtgggcgg gggtggggct 120 cggcgcgcac gttcacgggg cggggagggg gcgggtcagg ggcgggacca cagccggctg 180 ggccggggtt ctatgcgcat ctccggggag gggcggggcg ggggcggggc cggggcgggg 240 cccggtcggt gcactccaga cggcgggccg ccccctcttc ccgccttcct actaccggcc 300 caggattagc gccctgggag cgcgcgcccc gctgcctcgc cgccacactt tcctgggagc 360 ggcggccacg gaggcaccat gaagaagtct tactcaggtg ggcttcgcgc ccggggtggg 420 gaggggtcgg tgtcccggga ccagcgctgc tcacctgagt gcctgcggcc gggagtggcg 480 aggcgccccc ggagctgagc gagtccccgc ggcgggcaca ctgcaggtcg agttcctccc 540 aggacagggc 550 <210> 145 <211> 25 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 145 acctaaccta atctaatcta atcta 25 <210> 146 <211> 20 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 146 gttttgtttt gggaggaatt 20 <210> 147 <211> 423 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 147 agttcctccc aggacagggc cgctgtcggg ccgctttcga cctgagccga ccgtcccctg 60 cgctgtctcc agcccttgct cgagtgtcgg aggggctgcc ctgggggacg ctccctcttc 120 ctcgcccctt gcaccctcgc aggaatcgct gactttccag gtcggccggg tgctttgggt 180 ccctgtgcgt ctgtgtgggt gaatggggtc ggggctaggt ggaggggtgt ccttgggttc 240 agcctctagg gctggtggtc caggccgcag catcctttct tcggattctc ttcggtttct 300 cctctactta gtggggcacg ggacggcctc cagatgggac cgtccagcag cgcccaaact 360 tggcgactcg ggttcacgtt ttgcgctcag gacgccgccc gcggctgaca tcctcactcc 420 acc 423 <210> 148 <211> 20 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 148 aattcctccc aaaacaaaac 20 <210> 149 <211> 20 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 149 ggtggagtga ggatgttagt 20 <210> 150 <211> 282 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 150 cctgcctgtg aagatcatat gggccaggct gcggagggcc aggcatgccc gccgggagtg 60 cagctggtcc acgggaagca tctggagtgg ctgggaatgg gcgcaggagc agcgccgtgg 120 gagcacaggt ctctttcccg gggcggctca cctggtgtct tggttcctgc aaggtaggcc 180 gaaagggtgg ggaggaaact gccagctcct tacagcgctg ggatggtggc cccagggttc 240 ctgaggccag cggatgtggg tgcctgtcac catgtgggtt gc 282 <210> 151 <211> 27 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 151 cctacctata aaaatcatat aaaccaa 27 <210> 152 <211> 28 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 152 gtaatttata tggtgatagg tatttata 28 <210> 153 <211> 459 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 153 gtgtggtagg aatcttccag gaagtccccg tcccgttcgc cctctctgcc tgggcgggga 60 cggcaactgc ctctgtcact gcagactaat gggacggagg ggggtgactt ctcagggttc 120 ctcctgggca ggtgctccgg aaccttttct cagcacgctg gcctggggca cggccgttcc 180 tcctgcccag ccacgttggg gtacagggtg aagaagggct ggggccagcc caggacagag 240 gaaggcgagg caggcacgca ggaactgggc tttttaaacc cttaagccca aggaaatcgt 300 agcatcgcgg gacagggaaa atgaaagact ttggaagtcg tcaggaattt gactctgtga 360 gttggtttcc aagagtctaa gttaagcatc tccaagtgga tattaaaaag gagcagcaag 420 cctcggggcg gcgggggctg gaggaggtgg agagaggag 459 <210> 154 <211> 26 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 154 gtgtggtagg aattttttag gaagtt 26 <210> 155 <211> 22 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 155 ctcctctctc cacctcctcc aa 22 <210> 156 <211> 260 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 156 gaagaaatta gaccagacaa agagtgtttt tagaggagga ggaggaggag gaggaggctg 60 agagagggag ggcgacgggg gtgagaaagg ggaggccgcc tctgagcggg acgccgggac 120 tcccgccgct gctaaatata tccgtaggaa tggagaggga ccggatctca ggtacgcaga 180 cagccccctc cccatcggcc gccccccact gccctggact cggggcttta tttatgcctg 240 ggggaataag catgcaaagg 260 <210> 157 <211> 27 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 157 gaagaaatta gattagataa agagtgt 27 <210> 158 <211> 23 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 158 cctttacata cttattcccc caa 23 <210> 159 <211> 4133 <212> DNA <213> Homo Sapiens <400> 159 aggaccaaaa actctttctt ttaaaaagat cttagaagtt cctcctccag agaagacaga 60 aaacactgac aaaccgcaca ttgtgcagat gttcagcccc gaaatgcagc ctcgcagccc 120 ttcactccgc agtccaccgg ttgcatctgc acctccgggc agcgctcctg cagggcgcaa 180 acacccagag acccagggac ccggcagccc cgcgcaggcc tcccgcgtgc accgctcagc 240 gagcgggtct ttcgcagacg gcgggatgcc ccaggagacc gcgaggccgg cgcagcccgg 300 cgagctcccg gagggaaggc ggcgtgtcag aaaggatcgg accccagcaa tggccccgga 360 tcggtcccgc gcggtcgcct ccttttcccg ctccgccgcc gggacccccc tagccagtgc 420 tgaatttccc aactgggaag gaccgagtca ctccaccctc cgggaagtcg cgcgctcatc 480 cgttttcggc agcgccggag cccgagccgg ggaccgggcg gacacccaca gagtccgcac 540 cgcagcgcgc tgcacgctct cgcccccgcc cgccggcccg cgccccagcg aactaaccgc 600 aaagttggcc cgaagtggcg acggcgctct cgtggagctc acccgccgtc tcagcgcgcc 660 cccgagcagg gaccgggcct gccggggccc tcgccgggct cgcgcgtccg catggtacct 720 gccgcacgag ccgctcccgc gccctctccc cgcgcccggc cgcccagctc ggcgccggcg 780 cctcacgctc cccgagcgca ggagatccct ccgccccggc cccgcccgcc ggcgccggcg 840 ctcatttctc gggcgcggaa actcgagccc actttccccg gctgccggct ctgggaccgc 900 gggctcggcc acgcagtccc gcccggaccc aaagagcccc agtccctgcg aacaccaggt 960 ccgtgctggg agacgagaag gcgcccagcg gggtctagcg cggctccgag gggcagggcg 1020 aggcttgtga tgccgaggtt agttacggcc agccacaggc gctgtgcaag gaattgggga 1080 aagctccctg ccaagaaagg gaaacgttag cttagctaaa aaaaaaaaaa aaaaaaaaag 1140 gctggggcct aatgagaaag cttcccagag gcatcccttt agcttttcca tagccttctg 1200 ggagcccctg aatctgcatt tgaatggcgc ggctctgggt ccgcgaaggt ttggtgggct 1260 gaagtcgtcc ttcaggtctc caaaggaatg cagctaggtc ggaatctact tcctccttca 1320 atccccagaa aatggaaacg cttcccccgc gacctttttc tgccgagtta gaccccaggc 1380 cctccccgcc gcgggcgcct ggcctccccc gctgacaccc cggacgccca ggcctgtggg 1440 acaaaaggca gtcgcggcgt cccgcgggct tcctagcccg ggagtcggcc ccaggggccc 1500 caaagcgtga ccccaggccg acaactgcaa gttcctaggc agaggggaag ccccagcgcc 1560 gagaagcccg ctccgagaac tccccgcgcc gggcgcccag cctgagcgtc ccgggcgcgg 1620 agcccatccc cggtgcgggc agggctccag ccgcaggctc ggcgcagggc ggactcggcc 1680 gaagcccgga gggccggagg cgctgggacg cagcccggac aagagggcgg acttgatctc 1740 ggaaagtttg tgggactcag gcattttaac actgggaaga caaagagatc cgatttccct 1800 gggactggtg aggggagctt ggcggggagg ggaacggcag ggcagtcaag tgtgaaagag 1860 aatttcctgg gttcaaagtt aacgcagtca ccttataagc catcttagag gtgaccggaa 1920 aaaataataa taataaaggt gtctagcagg ttgtggctgg gaaggaaaaa taatgcctgc 1980 aagatgagtg tgccgattcg tagccctata ttccctgccc accagttgga atacacatag 2040 attcacacat ccagcaaatg caaactccat catccaaaga cgtgtttgtc ccggccataa 2100 ttgctccaag tgcttacagg tcaatttcat acatggaaca cctcgaaagt gggtgacctg 2160 atctccaagc ccaaccggct tgtgccgctt gccgaattgt aaatctcagc aaaacccaaa 2220 cacaccggaa ctccagccgt ttcctgggag cgaggaagcg ggagtaatgc taaaagggga 2280 aaagaagaac agtaaaaaaa gtacaaagat accattccct gacgtaaaat cacgggattt 2340 tttttaaatg gcacaagaga attcctggag aagattacca ttaattaata agtaataacg 2400 cttcctaggg cttactagat gttttacatc tgtctgggaa tcccgatttt ccaggctccc 2460 tgagaaatct atctgcctgg aagaagttgc acttcgtcgc cacaggagcc gccgagagcc 2520 agggatggag atttcagact taggactctg ccacgattct actgatcctt aagcgccaac 2580 agaacgaaat ggacatgcct attagctacc acaaatcgaa ttattttata tgagagagag 2640 aaatgtggtt caagttccac atttgtcctt taaataatcg accctcccta accctgtccc 2700 caaaggctcg tggaaattag ggagggggtt ggggagacgg ttccagaaac aaaacgcttt 2760 cctccagcac ggcctctaca tccagtccac ccaagctgat ttttgtaact catataaaga 2820 atgggcccgg gtgggtggtc agtgaagact ggggtgagca agcgcccacg tcgccgagcg 2880 ccggggaggt ccaggttcgc ctccgcacag aaccctgcaa ggagcgcgcc tcgccaggtg 2940 cccggactag agggcgctgc gcccctgcaa atctcgcggc cccgatgcgc cctccctagg 3000 caccattgct ataataagtt acattcaaaa taatgcacaa acagcatcgc ctctcaagtt 3060 ctttttaaca gtgctctata tgtattttat gaactcccaa agctatgcat acgaatcttt 3120 catcgccgat ccgcacaaag ccagagggat gcgcagctcc tggagccgag aacccgtagg 3180 gcgcacacgc ttccccgcac tcgcttagag ccacacaccc cacgtaattt cattaacgtt 3240 taaacttaaa tgccaaaagg catgcacgat ttgaacaaag aactcaccag tctagccgag 3300 tcctcggccc tgggctctaa agtcctcggc agctccgtga tcccctcgcg gtgtagatat 3360 gtgttaagag ccgggtttga agtaccaact ttgcctcccc gggatcttca gcatgtccct 3420 aaccagagtg ccaacgtccg tgccgccggg acccaggcgg ccgcatctcc ggaggcttcc 3480 gaccagggca aacttaagca ccaaacgcag gcgaaaagag agtgcgcggg gccggaacga 3540 gggcccggga gcagccaagt ttgtcaggac gtgcccaggc agccagccgc cgagttgagg 3600 agttgcggcc gccggctgcg gcgactcgct gcctctttcc ccactccctc ccccttggag 3660 gcggtggggg aggggaggtg acgtcagcgc cccgcctcgc cccccgcccc gggcgcggac 3720 gggattctcc ggctgggcgc gccaccccga cagtggcagc agcggccgtg gaggctgcgg 3780 gggtcccggc ctctgcggtc tctctggccg gccgcagctg tggcgcgggt gaaacgcccg 3840 ccctcctcct tcggctgcgt ctcccgggcg ccggcgagcg cgggcgttcc tcgcactcag 3900 cgcctggagc cgcctggagc cccgctgcgc gcacttcccc ggctcgcgga gcccctccgg 3960 cggcgtttcc cacgccgcgg actgcaggtg atgctcttcc tcttctgcag ccgaaattcg 4020 tcgcgatgtg tcgcctgcca gatttttgct gggcggaagc atgaacagtc tctgcagact 4080 ggcctggacg acttgtactt tgtggccctc caacttctgg atgtgaattt ttt 4133 <210> 160 <211> 4318 <212> DNA <213> Homo Sapiens <400> 160 cacacagttc atcagtgaca gagcaagatg agacttgaac tcatgtcatt gacttccagt 60 acagtttaca cccctggttt tacagatgaa gaaactggcc ctaggaggga taaatgactt 120 gcccacttca ttcaacaact gtgtaccaaa cccatttcca taagtgtgtc agcaggacca 180 gctctgagca aaaatgaaag tttagcaaag tttaactttt agcatacccc atgtcttcat 240 gattactctc acccgcaact gacacatact tttggtattc tgtctcccag tcactccaga 300 ccatgcaatc ttggcttgga gacctggttt cacctactgt ccctccaccc ccagcaactc 360 aagaggtaca aaaaaaatcc atctccaaat ggccacatac tgggcagggc aggggcaaag 420 agaagtgact ggtttccggt tggaagaagg tggtttacca cccagctctt ggctattgtt 480 tctcctcaga ctcagtgtag acaccctcag gctggcttcc tcatctcctc ccactgaggc 540 taattactct gtcccattgc agggccccag gctctcccac ctaaggtctg ccccgctccc 600 ctagcccctt ccccagcagc cccaagggtc cagtctgtgt ttgatcaccc aggattatta 660 gatttcaaag ctgtggaatc ccataatttt tacgagcata tgctctcctc tagggtcttt 720 tcacgtctga aaaggcggcc agcagctccc tgccacttct ccacagtagc agtgcaggcc 780 agctgacaag gattacaaat ccctagtgtc tcatagctgg cgcctagata gtgtgggtga 840 cgggtagaat aagagccctt gaagcaagtt cagaaattct aataagctga aatgcagcag 900 agactgcaga ggcacaagga aagggattag atacccaaat cctgcagggg ttcaggaggc 960 tatgcttcaa agcccctttg attcctgcct ttcagctctc tctagcggtc accaagcgca 1020 aagttctatg cctggttttc aagtcattta agcagtcttt tctagagacc tgctgcgtgt 1080 cagacactct gctagaatcc gggaacttca ggaatgaaag gaacataagt agaaaaaaac 1140 cagaagaaca caaagagttt gtactaccta acttccaaga tacccttttc ttctctgggc 1200 gccagtaccc agagagtacc gaccttagcg ccaaaattcg gtcctctctg aggcagatca 1260 ggagccacca cgcccccagt gaaatggagg cggcaggaat cccaccccca acccctcttc 1320 ctctccccac gactatcctc ccgggggcga gagtcgcccg gaagaactac ccgcgcctcg 1380 gcattggttt cctgctgagc cccagccgga taaaattagt cgattgctca cactaacaag 1440 tgtcagagtc cgcgtccagc tgagtgggtg gggagagcag tactgggccg ggccgcattc 1500 ccgcccgggc ctgtcagagc agcggacaga cagcacctgt cgtgggcctc ctcgttccct 1560 cactcctgcc agagcctgtg gcccccccgc ggagaccggg gactacactt gggagcatct 1620 ttccccaact ctcgtcaccg cagagaccgc gccgagccca cctgccaaat gttaatacac 1680 tggaatgcca ggggagggga aaagaaggtt gcacttctac tctcctttcc caccacacac 1740 ccacccttca ctgacctcgc cacgactggg ccctggcatc cgggcctggg ggtgctaatc 1800 gacactattt cccgccaggt ccccatgccc actccacact ctgggactgc ctgggggtgg 1860 atttggccct ggcggtcgct cctggtcctg ccgctggcct ccggccacct tgggcgggga 1920 cgcggagagt ggggttggct cctcccccgc cgcgggtctc catccatttc cccatttggg 1980 aggggtaata acccgggagc cgcgccacgg aaatgcatct tcccctgcta ttcagacggg 2040 aatccgccca cccatgacaa ccgcccttcc cgcctaggga aagggggcgg gaagacctag 2100 cctcgggccc tgccaactgc cagcaagcca gacggataga cagcagctgc tgcgtgtccg 2160 agctcagctc ctcctcgatc ccccgccctc tacctccctg ctcgctccac cgacaccagg 2220 ggccgtagcg gcgacggcgc cccaccccca gcgctcggtc cggagccctc gaggtgatcc 2280 gggctgggcc tgtcgaggat cttttacaat cggcggcccc ctattctctc ccgaccggcc 2340 tcgtccctag cgtcccaaga gcgggatcag gcggctgcta gcgaaagacc tacaggagcc 2400 cagactcgag gcccgccagg atgcggagac tgagggcggg ttcggccgcc aggaagcgct 2460 cccgcccggg gcagcaatcc tcctccgccc tcctctgcaa cctccaaccc gggagggccc 2520 tacggggcct cctcctccac acagtgggtc agcccagtgg ggctgctttc tgccaaagac 2580 ttggcccacc cttcaagcgc cccttccccc agtctccata aaaactcttt cagaactccg 2640 gggaatcaac catgctggtg ggagctccca gctcaggcct actcccccat ctcacagttc 2700 ccgatcacac aggggagcac gcgggatttc ctaggcttga gaaccctcct ccaagcctgg 2760 acggagcctc aagagtggtg agaaggacca gattgactcg aagagccgcc ctcctcagtt 2820 tgctcctctc ctacactcct ctaccctagt ctccaccgac ctgcttcctt ctgcgcttgc 2880 ctagtggggg gtgaaggaga ggacaactac cttcacttct ccccccaact ttcacataca 2940 ccctccgtcc cttaaggtgg agtctcctgg gaggcgggca gcctcgcaga tccttctgcc 3000 ttaaggcctt gcaaaggcag agtttcctcc tgtcagtctg gggtcttcca gctccctgcc 3060 gcatttgcca cctcctccca cactcctttc atccttcccc gcagcatatc tggacataga 3120 ccacccctcg accccgcaaa aaacaaaaca aaacaaaaca aaacaaagcc ttgagaaatc 3180 tccaaacacc tgtgcgtgga cgaattacag ttcacagttg ctcctatatc cctcatcaca 3240 attggccctc cccccaaccg tgggaggcaa ctgctcttaa gccgggttat agttggggga 3300 attgaggacc ggggggaact gaatgtgggt tttgaacgct tctgcaaggc cctttccacc 3360 ccacttcaca gaaagtaggg aagtgagcaa atctctcatt ttccctgact tcagaaagcc 3420 tgcttgctgc tcctggagtc agcacctgct cctcccttgt ccactctatc ccccaatgaa 3480 ggcactattt gggagtggca ctacagcccc aagatggagg catggagggc agcagaagcc 3540 gagccacagt ccttgtgcac cccctggact tccccaagga gggcatgtgg aagagaaagt 3600 ctgcctttct ctgggagtat gggtcattgt cttctaggtt cctctccccc ttaacatgga 3660 ggaaaaactc caaaataagc ttgcgtgtgc tccactccct cagtccttct ctcatgattc 3720 aataaaatta tcatcactga gggctaattt ccagggcttt gcttgatgcc cacaggccac 3780 aaaaggaaga attctttggg ctggttattt ggggacggga gggtgaggag cagctcatgg 3840 gaggctctgc tttcgtgaga aaggatttgc atgtctaaga ggtcaacaca gctagtccag 3900 ggcttcctct cttccagact tccagccctg catcaggcta cagagaggaa atggcaaaga 3960 gcagcaaata ttatgcaaaa gggtaaagga gctcccaagc taggagctgg gagctcctgg 4020 gaaaagaaaa gggaagaaca tgtctaaacc cctgcccaca gctgggcgtg gtggctcacg 4080 cctgaaatcc cagcactttg ggaggccgag gcaggcagat cacctgaggt cgagagttcg 4140 agaccagcct gaccaacaag gagaaacccc atctctacta aaaatacaaa aaataaatta 4200 gccgggcgtg gtggcacatg cctgtaattc aagctactca ggaagctgag gcaggagaat 4260 cgcttgaacc tgggaggtgg aggttgtggt gagccgagat cacaccattg cactctag 4318 <210> 161 <211> 3324 <212> DNA <213> Homo Sapiens <400> 161 tctaacctta acctttctac aggaataatg ctaattagcg aggcttaatg agaacttccc 60 ccaggaagcg cagcccggta ggggcggccg gactcgggca aacgcagctc cgggtgggag 120 cagggtcact tctgctcccg agcggctgga ataaaaatgc ggattgcact cccccctcct 180 ccctatccaa agtgtccagc cttgaagaca aggtggaggg aggagagaga gggcggaggt 240 gtaaatccaa cttaacccct gcgcgcgccc tcgaggcggc cggctgcccc cgccccgccg 300 tgtcccctca ttaaggaagg ccccttcgcc aggggccgcc aacgcccgcg gcttccggtc 360 agacggtgca cctgagaggg acaccccgtc ccctcccggg agggacccgg gcctgctgaa 420 gtgggctcaa ctctgcaaac cgcgtctcaa ctccccgcgc cgcgccgggg aacccctccc 480 tgacactcaa cgcttcccgt cctcacatcc ccaaacacag tccacttccc ttctcgtggc 540 ggccgcggca acccgagccc ggcccccgcc ccgccgccag agaacgcctc cctcgccggg 600 acgcggtgcc gagcccgctg cacaccgagc ggccgtggca caataccgcg gcgctgcgcg 660 cacaatcacc gccccccagg acccgcggcg cgcaccccgg gagtggggtg cgccccgcga 720 ccctgggcgc tcagggccag acacacctct tgggcgcccc gcggccccca cagtgcagcc 780 ttcatcgccc cccctccact ctcgggcaca ctcacccgcc ccccgcccca gcccactcgg 840 cccagggcgc agccgctccc ccgcgccccc tccctcagcc ccggcaaagg aagctccccc 900 tgcgcccccc tccccagaac cgcccccagc ccctcgcccc cctaaccgca gctcaacggc 960 cggcggcagc agccggagaa ggggggcggc ggcccgggcc ccggaaacgg cccgatcgcc 1020 gggatccggg ccggactccg tacctgggct ggaagcgagg cggagatggg cggtcgggat 1080 ccgcgagtga gcggggcggg cggcggtgac agccccacag ctccagctgc tgctgctgct 1140 gctgccgccg cggctgcccg gggagagggg ctggcaccac cgcggcgcgt cactgcccgg 1200 cccgggggcg ggggtggcca ggaggagggc ccaggcgagc agcggcggca gcggcggcgg 1260 cgccgcggcc cggaggaagg gggagggggc accgggcacg gggaggcggg agagggggcg 1320 ggaccgggca cggggcgggg gcggggggga ggggagcgca gggagggcgc aggcaggggg 1380 agtaggagga gcagcaggag gaggtggcgg aggggcgggt gagagggagg agtgggcacg 1440 gggggaaggg gagagaggaa aaggaggcac ccagggagag gggagaggag aaaggaggga 1500 gagaggcgcg gggggagaag aggaggaagg agggggagct gggccaggta gggggggata 1560 agggcgcgct ggacgcgccg ccgtgcgctt cggtggggag cgcgctctta agggggaagc 1620 gcttcgagga agatccttgc acggggctga gcccggaaag aaggcgctgg gatctgtgcc 1680 tacccatcgc tcccggaggc tgcggtctct gggtccggtg ggggctgggg ggagagggca 1740 cccggcgggc tgtctgcggt caggccagga gagggagact tggcccaaat aaagtgactc 1800 aggcaccctc aggaactctc ggcgcccggg gccccttcgg gcagccttcg acccccatgc 1860 gtctttcggg tccccaggga cgcgggtact tgtggggcgg ggctgccggg cctcggggtt 1920 cggctccccc gggcggccgg agcgagaccc cgggctggga aagccaggca cgtggccggc 1980 tctcggccgt acccccgccc cacccccacg gcagggcccc cagtgcttga tcaagttcaa 2040 gctcgagctc ctcggcgcgc tgcccaccgg ctgcccctcc gcgcccctcc cccttcccca 2100 tccgcaccgt ctcgctcttc actcttcctt tgtctctttc ccaccactta gtttacaccc 2160 cctccgccct cctccccgcc ccccgcgggc acccgagtgt ccgggaggcg ctcacctgtt 2220 cgacccaaac atctacgcga cccccagcgc ccgccgcccg cgtgcccgcc cccgccccgc 2280 cgccggtcat tgtgctccgc cagcccacac cgggccgggt cctgacggcg cgcgagccac 2340 agttgtaaag taataggata atctcgggga cgtcgctcca gcccagaccc gggcacgcac 2400 tgtccgtgga gacggcaccg ccggggaggg gagccacgcg gattccagat gcggtccccc 2460 aggcggacag acccttgccc ggggcgcagg aggaggcagg actggcatcg cggggtggga 2520 gccctggacc tccgagcaac ctcggactcg gcccgaaaag caacactctc atcaccaaac 2580 cgcagaatta gaccccgatg gagaaaatgg gtcaggggat ccattcccac cccacccctc 2640 caaatccaga ccctccgcta ccacagatca gcctcgaaaa aagcttgtgc ttcaacaagg 2700 atggggaact gccctcgtgg aattctgtgg ggaaattgcc aaaaaaaaaa aaaaaaaaaa 2760 aaaaaaaaac aactaaaaaa aaaccctgat aaggatccca cctcctgatt cctctggtcg 2820 catccgaaga ggaagggcaa tttctactga ctctttacgc taccattcat tcacggtgga 2880 accagcagag aagagaaaac gagacagcca cagcgattgt ttgcaatttt gaaacagact 2940 gcctttaacc ctccaacttt ttttctgtaa aaagcctttt ttctttcttc ctctgaaagc 3000 tttgcattgt gaacaatcca tggtaaacaa ggctccctct acagccgcga gtgcgaagta 3060 caaccccaca ggttcagagc ccagcgttta cccgtcagaa aaataaaatg atgacaagac 3120 atcacattag cgccacgcag gcttccttcc gcacatgctc aagactctgc tgtcaataga 3180 aaactcacac tttcttttta aaagagggtt taggcacatt tactcatttg caccttttat 3240 tcctgaaatc aaatgtgttt tcaaaccaat tcactctccc cagtttactg gatcttctca 3300 tccttggtga tgtggggcag gtgg 3324 <210> 162 <211> 4431 <212> DNA <213> Homo Sapiens <400> 162 ccacagctaa tgtttaacac ttcaactctt ccaggcccag aatcttccca ggactgactt 60 tgtgcttatt tgtgccaaaa tgtgttaaat tagacaggaa ggggaagcat aaaattcaat 120 tcataatcca aggcaagaat ctgagctttg gtttgaaaaa tgaaaagcta tggagtgaca 180 taacatactc cgacccttca aacaatcaag atatttaact ccaaagacat ttctcaaata 240 agagacagcc caagttcaga ctgcccacag ggcaccagct cccagaaaaa tgctatggcc 300 agagacagat ctgaaatgga gatacgtctc aagtccagag ctctggagct actaccagac 360 agcatgccag gagaagacaa cgagaaaaag gagagatcca catcaatcct gttccatccc 420 ttctccggag gcacacagct ctgggctgat ccctgggatc agctgattca ctggctgtgc 480 cctcttggtg cccgccgcct gcctggaaag gcagctgcct gctgaagagg aaaagttggg 540 aacgcaattc ctaattctca ggacaacgtc tagtaccatg ttctaccttt aacctgtctt 600 ccctaaacgg aaacagacaa ggccatcctg aaattactca gctactcatg aaacagagtc 660 tacaattatt tttccttcct tttcaacacg attagaaggg tgatccccca aatgcggcct 720 cttccacagc cacgtccgga ggggcatccc ctagtgtccc agcaagtgcc ttcagcgaca 780 ccagaatgtt agttaagacc taagacacat ttctccagct gcctcccgcc atttgtcaca 840 gaaaataatg ctgctgcacg cccccaaaac gccgttttac aagcagactt ggttttcagt 900 aactggtgag gaaaagtcac tggaaccaaa caccattcat acagctatcc agagcggagg 960 ccaccgccct accccggcag aggcacatgg gggcagcagg caggaccgag aggggctcga 1020 aggcgccgca ggaggagagg ctgggcgcag acggctcggc cccaaaccac acccagcgcc 1080 aggaaacgca aggctcggga cgaaccctta agaagtcgct gctagggaca gggaggttgg 1140 gagcagggag tgacgccaca ggaaccctga atccccccga gtcccctccc aatcaagcca 1200 aggccgagca aggggcgccc catgtaccgt aagccctcaa cccaacactc cggcaacgac 1260 aaacagaatt ccccgacctc aaaggccgtg aagcacgcgc ccttcggggc cctgagtgag 1320 ccctcaaacc tccgtgccga tcttccaaac ccacctcccg ccttcctgga atgggcgcac 1380 gcgaggcacg gatttcagga aacctctgcc gtgacagctc acccacggtg gaggcggagg 1440 cctgggacgc tggacggaga aaggcggcca gtggagggag gaggggtagg tcggcaacgc 1500 ggtggcctcg gacgtccgag ctgcccggac gaagcgctgg ccccactccc gcccttggtc 1560 gccgcggtga ccccacccga gccgtgacct cccccaagat ctcagggccc gggcctcccc 1620 gctgcgccgg ccccagggtg ccaccctcgg acgcccagat gcgccctgga ccctgcgccg 1680 ggatcctgaa caccgccgcg ccttcatccc gcgccgagcg cgcccggccc tgctccggct 1740 gcagcgggca cgagccccag gcgggcggcg gggacgcagc gcccgcagtg cgactggcgc 1800 agccgctgag gcacggggcg cgccgcccgg accccgaccc cgcggcgcta ggagaggcgc 1860 gggcgccggc tggagagccg cacctcccgc cccgccgagg ctgctggcca cgggcgcgct 1920 cgccccaagg gccgggcgga ggacctgtcc cggattccag aggacgtggg tggggaaggg 1980 acaaggatag ggacaaggga ggggacgcga actgggccga ggtgtgggtc agtcctggtt 2040 cgggaaggga ggccgttggc agggccatca ggatcctctc tggacatgga aggacgggtc 2100 tgccctggac ccagggattg ggaaatgtgg gttctctcag aacctgggga agtggggaga 2160 gggtctgttc tggagtgcgg agggagatct attccgggcc caggacaatg ggggtggggg 2220 caggacggga atgagggggc attcctggtg cagggagggg agacggagaa gtagtagggg 2280 gtctgctccg ggcccgcggg ctggggacca cgaagtgtag gagggcaccg tccaggaccg 2340 ggatgaggag ggagaggggc ccgttgtggc cctggataga gggggaggga aagtgcgccc 2400 cggcccgaga ggaggagcag gagggtcagt cctggacccg ggcttaggaa gccgggaggg 2460 aggttcggat ccgcctcaga gacagggcga tgaagatctg tccaagtctt ggagtggagg 2520 gaaggatgtc ggcggtgggg gaagaggccg gccacggaca gggaaaggga gtccgtcttg 2580 tagggcggac gggcggtcct ggggaaggga gaggccgcga cgcggggggc gtccggcccg 2640 agcggggccg ctcaccttgg gtttgtagag ccactttcgg aacctgttca tcatcgccgc 2700 gccggccctg gccggactcc gggcggccct cgccctccgc agcgctgcgc ccgggcccgg 2760 ctgaggcgcg gggcggacgc ggaggcacgg ccggagcccc cgcgctgtcg cagggaggct 2820 ggctagcgaa gcccggagcg ccgagcgggc ggcgggcagg tgcgcggggc aggtgcgcgg 2880 ccctgagtat gctctgcaag cggcgcgccg ggcagacctc agacccggga gtgggcgctc 2940 gggcgcacgg acagacgcgg gcacgggggc gcgcggctcc tcgctgctca ctgacaccca 3000 gcgctccgct ggtcacggcc gccccgcgcc gcacatgcgc ctagggcgcc gcgagccccg 3060 ggcccaccgc gcgctgcggg cggggcgggc ggggcggagg cggcccaatc cctgcgcggg 3120 cgccgcaccc cgcccgaggc gcgctccctg ccggcggggc gacccgccgc gcccgggtat 3180 ccaagaaact acaagtcccg aaaggcatgg cggggaggtg gcgcccaggg cttggcgtcc 3240 cgggccgcgc cgcggcgctg tgtattgtgg gagttgtagt ccacccgatg gcggcggagc 3300 gtgccgccgg ttgctaggtg acgacgccaa acagccgcgg cgtcctgcct accgggagct 3360 gacggacgac gactgccaac accttagccc cagctggccc aggaaactgc tgcggtggca 3420 ggtggcggcg gcaggagggc tcggctgccc cgagcgcccg ccaggtacgg gggcgggaca 3480 ggtgcggggc gacgcgccgc cgattttcat gacctgccgg ccggttccct ctcgctcgct 3540 gctcatcttg cttctcccaa acacctcttc tgtcttcttc ccagctcccc gatgaaagtg 3600 aacggtgcct cttttttttt ttttaaatca ccactatcag cggtgcgttc taaaaagata 3660 ctcttccgcc ctcgctactc cccccagtgg tgccctaatt tgtaccttaa aacgctcacc 3720 tcaatctgag tacctgctat gtgtcaagca gagagctaaa aacccacacg tggcctcact 3780 taaacttccc attgacagcc agagaagcag gcacaacgag gccggcgtgc cctggctgtg 3840 ggggttgcat ccagatcacg gcggatctgg gtcggcctga ccccacagcg ctgcactttt 3900 ccctgccgca ccaccaccac gtctctggct tgttgtgaaa cgtgcagatg taagacacag 3960 gagatggaag tcatgccccc ctcggttcag aattgagaag tctgacctgt tcctgcttgt 4020 cctcactggc cagtgccagg tgctcagaaa ggtccgtggg ctccatgacc actttattcc 4080 aacagacgcg atgtgagcct aggcgcgctg gcatctaaga tttctcttag ttgggggtag 4140 ggtccatgtt tatttttgag taactgattg attttcccta ctctcctctt cctaccaccc 4200 agtcgaccct ctgaagggca aaacccctct ggagtttccc cttatctcca attccttccc 4260 acttgttctt tctggaaact actcccatca gattttcacc caaccactcc tctgaagctc 4320 tttatcaaag tcatccttga ccttgatgtt gcaaaatccg atgatcgggg tcagcgctca 4380 tctcttcctt gaactgtcac taccacgtga cccagccgac tgtgccctct c 4431 <210> 163 <211> 3357 <212> DNA <213> Homo Sapiens <400> 163 tgaaattcaa acataaaatc cgctaataag gattaactgt atgtgcataa tttaaacttc 60 atccataaat ttaaccacac catttgattt taccagaatc aggctctacc ccactcctga 120 ctctgcccac tacccaccca gtacctctgg taataggtgt ctgagcgtcc acaggtggcc 180 cctgacttgc gaaagacttc gcggcgcttc cagccagggc ccagggccgg gcagtccagc 240 cagtcctcag ccatggaggc cacaggaagc agcagtagcc tgaaaggggg tggaagggat 300 gagggaaact gaggctctag gaagggacaa cactgtgccc caggccacac aaatcactgg 360 tatccattag tgcttgccca agccctagga cctgccacag gcaaccagcc catatatgga 420 aaagaaaccc ctcatattct caccccattc tttcctattc tgggcctagg atatcatcat 480 tcctcaaccc aaggatccct gtttcttatt ctcagtgtcc taatccccta ctcctctcta 540 tcctcagact gacaacccat catttctcct cactgccaat ccagaaactt ttcatccttc 600 cccctcattc ctccctgtca ctgacctaag ggcctctatc cctctatttt atcaccccaa 660 gacccccata gtccccatcc tcagccccaa agggccccat ttctcttgcc ctcactactt 720 gacttcagta gtctctcatt ccccccttcc ttgacccagg agttcctaat ttccctcctt 780 cagtgtttta accactccat tccttctctg cctgatgtcc tcttatcctg ctacctcagt 840 gttacaacct cgacttcctc tgcgagacac aactgctcca acccatagcc tgaacagccc 900 ctcatctttt ccattcctca cactggaagc ctcccatgcc tccccttcct cagcccaaga 960 cctcccccct tatttttctt ctccttcaat gttctcaccc acaatttctc cctagtctga 1020 gctcccaaac cttcctctac agccaaaaag ttccccactt ctcctcctta ctgttctcat 1080 cctccattcc tcccttatca tccagagaga ccctaatttc tcccctcagc attccgaacc 1140 ctcctccatt ctctctgttc ttgtcccggg atcatgccat ccctaactgt caccattctg 1200 atcccctact gctcctcgtc ctctatatgg ggcctcctat tcctcccttt cagcattcca 1260 aagcctctat ttctcctgtc atcagcctga gggcccctca tttctccctc tcagagttct 1320 gaacccccat ttctctctca acttcagatg ccccgatgtc tccctttagc gttctgatct 1380 ccaccattcc tctccgtcct cgtcccagga tcccgacact cctacctgtc agagttcaga 1440 gctgcattcc ttcccgtcct cagcctaaat ccccccattt ctcctcgtca gtattccgac 1500 gccgccattc ctccccctta tcggcctgag ggcccttcat tcctccccgt cagcgttctg 1560 agccacaatt ccttcccatc ctccgcctga gcgctctcca cgtccagccc caaggctgtc 1620 tcaccagttt ggcaccaggc cggtatcttc cgccactcta ggcccgtgga cccatggcga 1680 gggtccctcc tgcacctccc gcctcgccct cctccccttc ctcctcctcc gcggccgcct 1740 cctctgaagc ggtagctgtc gcctccgcgg ctgttcgttg ctcccggaac cggaagtccg 1800 ctgcctgcct ctcgggctcc gcctctggct aagcacctgc gcactattgc ctcgatgtcg 1860 cgtgccctta atagggaggc tcccgcgcct acgggccggc gctccgcagc ggtgcgcgcg 1920 cccccctgcc gagagccagt tgcatctgcg tgctgacgtt caacgacagc taaccccttc 1980 gagggactgg cagttgcggc tctcctcgct gcccatctag ctggcgcatg cgctttccag 2040 cctcaacctg aagggaagcg gtcggggagg gcttgcgcct gcgccctccc ttccctcccg 2100 cggtctccac agccgatacc gaacgcggca aggaagctgc ttcgcgcctg cgcactccct 2160 ggccctgccg gcgctctcct ctcccacctc tcgctggggt ctatcctgtg ttcgtgggtc 2220 cctccgaaca tcaaccccag ggggggtcgt gtcccgctcc ctcctccccg ccgaacagct 2280 gtgggagcgc gcggggcggg gaaaggggcg gtgccacacc gcaggtaaac tgaggcacgc 2340 gggagggcgc gcccctgcag gaggcggatc cccaacgtgg ggcttgtggg gaaaaggcgg 2400 ggcctggcgt ccacagcgga cgacagctct gggtgggaga caggagcatg catgggcggt 2460 gtcaccacac tgaaggcgcg ctgcgtagac cctctgcccg tgggaggctg ggaatgtggg 2520 tccctgggct ctcgcggggt gcaggcgccc cccatcttat ccagaagtct ggaacagttg 2580 caaccgcagc aatgtggaga cagcttcctt ggtttcttca aaattttatt aacaaaaccc 2640 agggagagga ggcaaggatg agtggactcc gcagccccac caggcactga acatgtcgac 2700 ggggacagtc cctctgataa aggcagatgg gcggtcaacc ggtggatggg cacagggaga 2760 accggagaaa cagatgagtg gaggaacgga cacacgggca ccgggcggct cccccatctg 2820 gaatgcaggg tgtaaggggt ccgggccagg aggctcagcg gtcggcactg gagcgcaggt 2880 cggtagtgag gggatcgtgc tggatcgtct ggtgcagcat cagggccagc aatcccgcgc 2940 ggtttgtcat ggctgtgcgc acattgcgct cctgctcaaa cagctcgtcc agcttgtacc 3000 actgccaagg gagcggcagg agtcctaagc aggaacacct gcagccccgc ctgccccggc 3060 cacgtccgac atggaaacct accacatgca gcaccaaaac cgcacagaaa cctaccacac 3120 gcacgcgctc caagtccact tccgcacgcc gcagcttctc ccagcagtaa tggcgattgc 3180 actggcgctt gggcaggcgg cagaagtcac ccgtgagctc aaagacatca cgtacaaggg 3240 ggcacccgca tacctcgtca gctggcacct gcaaggaggc caggttgggg ggatgaatag 3300 cggtgataag ggagaatagg aatgggggct caaggaggga gaaggaaaag aatggag 3357 <210> 164 <211> 2170 <212> DNA <213> Homo Sapiens <400> 164 gtgatttttt ttcttaggat ttagcagtac tccaccgcgc tacagcagtt agcatttcta 60 aagcacacac tccaacaccc ttcggccgta gcacattcaa tccctccgcc ggggcgtggg 120 ggtctcctcc cctccgagca cagtccccgg cttcccgatt tcctctgccc catccccccg 180 ccttccaagc acattgtgct cactcttcca ggcagctctt tcagcggccg ggcagtagca 240 gggttccgag cccgtcttct ccggggcggt cacacgtgtc cattccctgg ggttggggat 300 cgctcttccc gcttggctgc tgattggtgc ctccccctac cccacccttc ccgccgctct 360 ccagcctcca tcctacttcg ttccagctca atcagcccca ccgccttctt ccctcggaga 420 aaaaagccac ttcagagctc cttgggcgcc gttctcggct ggaataaaag cgttaagaaa 480 caggtggaaa gcacttcact tctctaggct tcatatttct agggtggaca gcccgctcct 540 gctccggctc tgccctcggc atcaataata actgaactcc cacacgtgca cgtttctgtc 600 tctagcccga ccgaaaggac caccccgcgg gccctttaaa aggacgcgac cactcaggcc 660 aagtgggggt gggagagctc ctggccgtcc tcccttggga aagtgcttca actccccagt 720 cccaaagtcc tggagggcgg agggcgcctc gtgagagttc tcgggggtgc ggcccgcgcc 780 ccctgggtcc tgcggatctg ggcccggggg cgcgcgcccc gcccctcccc ctccctggcg 840 gtgcagctgt ccgggcgggg gtggggcggg ggccggggcc cgcgtgggat taactaggac 900 cggggcggga gtcgaccgcg gccggcgggg agggctagcc ccgctctggc gggcgggcgc 960 gtggcagggg ctcccggagg ccccgagctc ccgggaggcg ctccggccaa cttcgggccg 1020 gtggggaccg ggcctgggcg cggggctctg aaggtgtgga aggaaagttt gggactccgt 1080 tattcttcca cagcgtcctt cctcccgtaa tatccagcct ctttatcgcg gggctcggga 1140 gcccttggag ttgatctcgc caccattatc cccccgggcg agcgcggagg acgggctggc 1200 cattctggcc aggccggagg tgttttccag cccggggctt tgtgataact gggccgaaac 1260 ccgagggtcc tggagcgcgg cgggtggcgg gagcttgcgg agcgcggcgc actcggcggc 1320 caggcatcgg ccagcccagc ggcagccccc tttctcctat ttttattttt atttttggaa 1380 ggagctgaga attagtcgat tggttggcag gttgaattgc cttctcttct atggcaatat 1440 gtgtcgtgac ttttcacctt ttgcctttgg acaaaggtga atggcaactg cgttggtcag 1500 tttttgtttt ctgttctgcg gatgggttcg ccgacgcagt aatcaaaatt agagccactc 1560 ttttggaaga gcaaatcgtt gttgttgcct ccccagcccc acggatctta ctttgtgcca 1620 ttttcgggtt gattttaact cgtttatttc agagctcttt gcctcacctt tatttttaga 1680 tttagtcgtg tttgctgaaa tatcagttgc ttcttctgtg aatgaagtgt gggaacttgc 1740 tctcgtcgca gttaatgaaa tcaggaaaat aaaaagatca aaagggttgg ggatgggaga 1800 atgaagagga atgtagacag atagtctagg gccactcact ggcttttggc gattcttagt 1860 tccttaagct gattaaaaca atgtgaggaa atgtgggctt ctccactttt taggaagagg 1920 taataacggg cattttacgt ggcgccacag cgtttgtttt caaagtttga acgtgaatgt 1980 agcaagcata attttattaa tgaaaatatt ctttagacaa ctgttaatat tgacgaaaga 2040 agagaaacag agacacggaa gctaaagagt tgggaatcct aaaggtcaaa ggatgtttct 2100 cagttactct gatgtcctgt gttttctttc agttggtaca aaatcgtgag tagtttaatt 2160 atatcctgca 2170 <210> 165 <211> 2251 <212> DNA <213> Homo Sapiens <400> 165 ggaccccgag ccgcccccag gtagccagga gcggcctcag cggcagccgc aaactccagt 60 agccgcccgt gctgcccgtg gctggggcgg agggcagcca gagctgggga ccaaggctcc 120 gcgccacctg cgcgcacagc ctcacacctg aacgctgtcc tcccgcagac gagaccggcg 180 ggcactgcaa agctgggact cgtctttgaa ggaaaaaaaa tagcgagtaa gaaatccagc 240 accattcttc actgacccat cccgctgcac ctcttgtttc ccaagttttt gaaagctggc 300 aactctgacc tcggtgtcca aaaatcgaca gccactgaga ccggctttga gaagccgaag 360 atttggcagt ttccagactg agcaggacaa ggtgaaagca ggttggaggc gggtccagga 420 catctgaggg ctgaccctgg gggctcgtga ggctgccacc gctgctgccg ctacaggtga 480 gatggcgttg ggctgacgtt ggggtcaacg ggtagagaac gcagggatgc ggccctcgcc 540 gaagagagcc aagaagggaa gagcgcgctc tccaaattgc ttttgtaact tgttttcagt 600 gagcatttta ttgattcaga atctatcgag aatagcacta gcgagctact tttcccttga 660 gatgggtctt attcatcttg gcaatggagt gagttggatt gtggggagga agaggaatgg 720 gaaaatcagt ttataaatat taatgtcagc aagagtgtgc tgttggcagg acgtatcgcg 780 agcctggaga ttttggtggc cgcagttggt aagtggctac aatccagaaa gtaggatcga 840 gttgctcccc ttgtcttatc agtgtatcgt ttctcgggcg cgggtctaac accttacaag 900 tggtaatttc cgctcacggc agctttgtct ctcttctacc atccccagac ccagccttgc 960 actccaaggc tgcgcaccgc cagccactat catgtccact cccggggtca attcgtccgc 1020 ctccttgagc cccgaccggc tgaacagccc agtgaccatc ccggcggtga tgttcatctt 1080 cggggtggtg ggcaacctgg tggccatcgt ggtgctgtgc aagtcgcgca aggagcagaa 1140 ggagacgacc ttctacacgc tggtatgtgg gctggctgtc accgacctgt tgggcacttt 1200 gttggtgagc ccggtgacca tcgccacgta catgaagggc caatggcccg ggggccagcc 1260 gctgtgcgag tacagcacct tcattctgct cttcttcagc ctgtccggcc tcagcatcat 1320 ctgcgccatg agtgtcgagc gctacctggc catcaaccat gcctatttct acagccacta 1380 cgtggacaag cgattggcgg gcctcacgct ctttgcagtc tatgcgtcca acgtgctctt 1440 ttgcgcgctg cccaacatgg gtctcggtag ctcgcggctg cagtacccag acacctggtg 1500 cttcatcgac tggaccacca acgtgacggc gcacgccgcc tactcctaca tgtacgcggg 1560 cttcagctcc ttcctcattc tcgccaccgt cctctgcaac gtgcttgtgt gcggcgcgct 1620 gctccgcatg caccgccagt tcatgcgccg cacctcgctg ggcaccgagc agcaccacgc 1680 ggccgcggcc gcctcggttg cctcccgggg ccaccccgct gcctccccag ccttgccgcg 1740 cctcagcgac tttcggcgcc gccggagctt ccgccgcatc gcgggcgccg agatccagat 1800 ggtcatctta ctcattgcca cctccctggt ggtgctcatc tgctccatcc cgctcgtggt 1860 gagtgaccgg ggctggggcc ctactcggcc tttttctcgc atccacctcc cgcgtccatt 1920 ccccgctccc tgctttccct ctgagtcctt ggcagtgaac gtgtcgcctt taggtcgggg 1980 ctgggattcc cacactgttt ctcagagcag gcccaaccct ctttgaagtc ccaaccctaa 2040 cgagatttag caggtgcttt gcccctacat cccccagttt atgttcccgg aagcctgggt 2100 ttctttctcc accgagacag cccttacccc ttgctgcctg acactggccg agtcttccaa 2160 gaaaaccccc cgccccctct gttagacgtg gaggggagcc tgctgtagtg tgacttagcc 2220 cattcctccg tactgtgaac tgtgaactgc a 2251 <210> 166 <211> 2297 <212> DNA <213> Homo Sapiens <400> 166 agaaaaacac caccgtgtcc ccccgtttgc atttaataca ctcaaggctc ctcatttatt 60 cctctggaac aaattcccag caaatattca cccatcgatt tgggagcgat ggatttttat 120 aaaggtttga tcgctttcta agtggtcgaa gtgatttgtt tccgtggtct tctcagtatt 180 gaagggggtg ggggaagcgg atttgagggg gtgcatgtcc ttgccgtcgg tgggctcact 240 ttctaaaaac tattgagatg cgccagggtg gccgtgacca agcgggccca gggtcaactg 300 tgtgaggggg aagcgcccct cagagcgcgc gcagcgtcgg gggtccagct tacgccgctg 360 cgcgcccttg tgcgcaccgg gtgaggatgc cgagctctgc gggcatcccg gaagccgcgg 420 tggaggcagg ggccccgctc ggcgcagtgg gcctgctggg gaggtgcagg ggaggtcctg 480 actcctggtc tattcccttc cagacttttt cgttcgctcc cggaccttca gggctctccc 540 tcaaactttc tcctgccccc ttcacgggag gttcctgtag cctctgggcc ttagggtccc 600 gtaagcctcg ggatcgactt gtgcccgggg tgggtgtggc ggaagcttga atcggattac 660 ccaggtacgc cacctgtaga cgtagtgggc gagggggact ttgctacctt ctcagcttct 720 tccctggacc ccgcagcgag gggaaccaaa tctctcccat gatagcccct ctggcgtcag 780 tctggaccga gtggctacag gttggactag ggtaggcaga agatgcactt ggcaccttac 840 cgaacggtat ttgaatccgt ctccattact cattaatggc gtgaccttag gcaacccatc 900 taaactttcc gaacctcagc ggtccccatc tacaatatgg gggttaatga taatgccttc 960 tccgcatgta ggtggattaa atggacataa agcgcctacc cccgcccggc acgtccaaaa 1020 ctctcattaa caggtcagct aatcttatta cgagaggaac cctccctcct ccgcttccca 1080 gagtgtgggc ggcatgaggc cacggaagca gctgctgcaa ctagcatttc aaaatccaga 1140 gactttctaa tggtggcagg gggtgaaagg gtagggggga ggcagggttg ggacaggtag 1200 aggtaggttc ttggggactt ccagtcttgg ggaccaagcg cttggaacta gctgggtttg 1260 ggcagaaaca agaaggcaaa tgacgggacc gccgccggag tccggacttc catccctgga 1320 gttcactgtc tctcccaggg aacagaggag tgtcctggtt tctcagcaat gaaccaggag 1380 agtgtgagaa agagcatttg tttcttctcc cgtggcccga caagccactc ttcggcagtt 1440 ctgcgagcag attaattgaa acgggcctgg aacttcatcc tctcctcccg atggagttgc 1500 tggaggtctg cggacactgc ctggttagcc tccgggacca cagcgccgtg ggctttccct 1560 cgtggtgtct gccttaaact tgggtgctat caatctatcc aacaatgacg gatgaccttg 1620 tcataacgac gccagtcaaa acattttcgg tctaactctc ttccaaccaa catcgaagca 1680 tcctgaatga gacccggatg aagtctgaac agcacgtttc ccaggttcag aaaacttgag 1740 tggtgggaag agaaaaagaa acaagcagaa atcaggaaag aatggctatt aattgctcag 1800 attggcaagt gctaaataag ttaggttgtt tggaaaaaga taaatgccgt ttcttctctt 1860 tacggtatgg ccagaacccc ggcgatggga aagtacctcc tgagtcggtc aatttcacac 1920 accctgcctg tgccctctac catctactac cgaaaatgcc aggaagagct ggggggcaag 1980 tgcctccttc gtgggtgcga gactgcatcg aagggctgcc ctggcacaaa gtctggggag 2040 aggacatggt ggaggtgggg ctgcactccc accctgcccc tctaacacca ggttttgggt 2100 agagaaacct atgcgtgacc tcctgcggca gccgcaggca gctgaccgca aacagcctcg 2160 cccgtgtccc ggagcagttg tgccaccaga cgtaacactg gatacttgtc tccgggcccc 2220 aagaaggaga gggaaagagc cctccagaag acaacccgag aaggggtcag cagagcgctg 2280 ggtggagtgc agactcc 2297 <210> 167 <211> 2590 <212> DNA <213> Homo Sapiens <400> 167 gcgttgagca ggcgcggtca cggtgctcag atctcccggg ggcatttcag ttcccgccat 60 ccagtggccc acggctgcgg gctccagggt ctgaggctgg ggactaccgt tgccgccgca 120 gtccccatat cccgaagttg ccttgctgct tgtgttgttt tcgcagatag catttttggc 180 gctctgtgcg ttccttccct ccccctcccc ctttcactcg ccctcattgt cctgagtctt 240 tgaaagttgg gagaatcgga gatacttctg aggactggta atgaagtctc acttaagtgg 300 gatgcaattc ccgccctcct acccccctcc aagaaggagg ttgtgttttc attttgtttt 360 gctttgggtg ctgaccttta aaaaattaga gcaaaatgaa cgtgaacaaa aagaaaagga 420 gaaatgtttc gagctggggc agagggagca gagaaggagc cctcaccgcg gccggaatgc 480 agagcggacc ctggcccagg actgggtttc cctttaggct cgggcctacc ctggccctcg 540 ctgttggaat ctccaggagg taaagcgacc tcgatttttg ttgcccgcat tcccgggcgt 600 gagtgtcctt cccaggaggc tcaggaggcc gtttctgttg cattctgagc ctccgttgca 660 aaaactgaag cccgtgggtc tcggcaggcc tcctagctcg ctcgccccgg gacaggccct 720 cgcctacacc cctggaagta aggagccccg ggctctttcg tccttttcgg ggtgtggagc 780 ccctggggcc cttgaaaggt gaggcctcag aggcgaggga ggggtgagcg gggagctctg 840 cccgcctgcg gctgcgcccc cgctgtggac taggaggcag gccaaccctc cggactttgg 900 gggaaaaacc acagcgggct ccttgcggaa actttggccg ttctaacttg ccaagagcct 960 gagtgaggcc ttggaagcct ccagccccgg ctcaggtcgg gacgcggctg ctgagctttc 1020 tcaggcccgc aggacagcgg cccccgccgg tggcgccgct gcatttaggc cctttccaga 1080 ccggtggcgg cagccaaccc gagacttgcg tccctcgggc ccggggcagc taggaggtcg 1140 gcgcgcagcg ggccgggtca ggactgggtc gagcagacag agctgcagcc cccgccttgc 1200 ccggcttctc gcggctggag agcagagcga tgtcacccgg agccccgcct gggtggtaac 1260 gagaccctgg ccagtcaccc ctgcagccca gactaacttc tttcaacagc ctctgatggt 1320 aattacagta atcgaagctg ccatatatct ttaggcaatt atgacacaca aaaagccccg 1380 aggggacccc ctggcgaggg aagttaagaa cggttttcca gcttcaggaa actccggctc 1440 gcctcacgtc ggagctcgct cggcttgcta aatgagagga gctttgcaac ggggtcaacc 1500 agcttgtctc gtgaccccaa gtcaccttaa cgtggctggg tggcggagtc tgaggcacag 1560 gcccgctatg ccccggaatt ttcgcgtccc tccctcctgg gccccgcccc agcccggttg 1620 cctgtttcta atctgccccg ggagccgcgg ctcagaggtc tgctcagagg caggactcgc 1680 actggtggtg gcctagaggg caacagtccg gaagctcggg cgggggaatc cgaggagggg 1740 cccccaccct gcactggtct tccctccacc ctcatcgggt tctccagaga tgttgtcatg 1800 ggcctcctgt ccggatggga agtggggaaa aagagacccc accactgctc ctcccactca 1860 ctcatcttgg catcttcaac agtgccacag ggaagaggac agctggggtg acagtactgc 1920 tgggccccaa acgtggaccc tggagcggtc agagggcgcg tgttaagcag aggatggttg 1980 taagatatgg aaaccaagtt taccgcttcc agagtgagtg cagtgcagcg gagctccaga 2040 cccggttcct gagcgaccag gaactccctt gggcgcagtg acaggcccga aggagtggag 2100 gacaagaccc gctgtgccct tgcctggccc tctccagccc ctccctccca cagcacaatc 2160 tcccctcccg ccctgtggga ggggggcgcc gagccggtgg ccgccgcgcc gcgcgcctcc 2220 cctgcccgcc tttgtcgccg tccgaattcc catgctactc tttttgacgg gtcactggtg 2280 gctctatagg caggtgctgc cgcggggttg taattacccg gccgagcctg gtcgttaccg 2340 aacaccccct cacccccaag cacggtcccc cgcgctctcc ttcccccacc ccctccacct 2400 gagacgagtc tgggacccac ggtgcaagct cgcccggacg cctcgggttc caggagcaag 2460 tttacacctg cggtgcctcg aggccctccc cgcgccacgc cctcacctcc cctactcccc 2520 tcgcccagac gttccactgc cgccccttcc cacctcaatc ccatcgtagt ccccaaccca 2580 agcgctttcg 2590 <210> 168 <211> 4133 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 168 aggattaaaa attttttttt ttaaaaagat tttagaagtt ttttttttag agaagataga 60 aaatattgat aaatcgtata ttgtgtagat gtttagtttc gaaatgtagt ttcgtagttt 120 tttatttcgt agtttatcgg ttgtatttgt attttcgggt agcgtttttg tagggcgtaa 180 atatttagag atttagggat tcggtagttt cgcgtaggtt tttcgcgtgt atcgtttagc 240 gagcgggttt ttcgtagacg gcgggatgtt ttaggagatc gcgaggtcgg cgtagttcgg 300 cgagttttcg gagggaaggc ggcgtgttag aaaggatcgg attttagtaa tggtttcgga 360 tcggtttcgc gcggtcgttt ttttttttcg tttcgtcgtc gggatttttt tagttagtgt 420 tgaatttttt aattgggaag gatcgagtta ttttattttt cgggaagtcg cgcgtttatt 480 cgttttcggt agcgtcggag ttcgagtcgg ggatcgggcg gatatttata gagttcgtat 540 cgtagcgcgt tgtacgtttt cgttttcgtt cgtcggttcg cgttttagcg aattaatcgt 600 aaagttggtt cgaagtggcg acggcgtttt cgtggagttt attcgtcgtt ttagcgcgtt 660 ttcgagtagg gatcgggttt gtcggggttt tcgtcgggtt cgcgcgttcg tatggtattt 720 gtcgtacgag tcgttttcgc gttttttttt cgcgttcggt cgtttagttc ggcgtcggcg 780 ttttacgttt ttcgagcgta ggagattttt tcgtttcggt ttcgttcgtc ggcgtcggcg 840 tttatttttc gggcgcggaa attcgagttt atttttttcg gttgtcggtt ttgggatcgc 900 gggttcggtt acgtagtttc gttcggattt aaagagtttt agtttttgcg aatattaggt 960 tcgtgttggg agacgagaag gcgtttagcg gggtttagcg cggtttcgag gggtagggcg 1020 aggtttgtga tgtcgaggtt agttacggtt agttataggc gttgtgtaag gaattgggga 1080 aagttttttg ttaagaaagg gaaacgttag tttagttaaa aaaaaaaaaa aaaaaaaaag 1140 gttggggttt aatgagaaag ttttttagag gtattttttt agttttttta tagttttttg 1200 ggagtttttg aatttgtatt tgaatggcgc ggttttgggt tcgcgaaggt ttggtgggtt 1260 gaagtcgttt tttaggtttt taaaggaatg tagttaggtc ggaatttatt ttttttttta 1320 atttttagaa aatggaaacg tttttttcgc gatttttttt tgtcgagtta gattttaggt 1380 ttttttcgtc gcgggcgttt ggtttttttc gttgatattt cggacgttta ggtttgtggg 1440 ataaaaggta gtcgcggcgt ttcgcgggtt ttttagttcg ggagtcggtt ttaggggttt 1500 taaagcgtga ttttaggtcg ataattgtaa gtttttaggt agaggggaag ttttagcgtc 1560 gagaagttcg tttcgagaat ttttcgcgtc gggcgtttag tttgagcgtt tcgggcgcgg 1620 agtttatttt cggtgcgggt agggttttag tcgtaggttc ggcgtagggc ggattcggtc 1680 gaagttcgga gggtcggagg cgttgggacg tagttcggat aagagggcgg atttgatttc 1740 ggaaagtttg tgggatttag gtattttaat attgggaaga taaagagatt cgattttttt 1800 gggattggtg aggggagttt ggcggggagg ggaacggtag ggtagttaag tgtgaaagag 1860 aattttttgg gtttaaagtt aacgtagtta ttttataagt tattttagag gtgatcggaa 1920 aaaataataa taataaaggt gtttagtagg ttgtggttgg gaaggaaaaa taatgtttgt 1980 aagatgagtg tgtcgattcg tagttttata ttttttgttt attagttgga atatatatag 2040 atttatatat ttagtaaatg taaattttat tatttaaaga cgtgtttgtt tcggttataa 2100 ttgttttaag tgtttatagg ttaattttat atatggaata tttcgaaagt gggtgatttg 2160 atttttaagt ttaatcggtt tgtgtcgttt gtcgaattgt aaattttagt aaaatttaaa 2220 tatatcggaa ttttagtcgt tttttgggag cgaggaagcg ggagtaatgt taaaagggga 2280 aaagaagaat agtaaaaaaa gtataaagat attatttttt gacgtaaaat tacgggattt 2340 tttttaaatg gtataagaga atttttggag aagattatta ttaattaata agtaataacg 2400 ttttttaggg tttattagat gttttatatt tgtttgggaa tttcgatttt ttaggttttt 2460 tgagaaattt atttgtttgg aagaagttgt atttcgtcgt tataggagtc gtcgagagtt 2520 agggatggag attttagatt taggattttg ttacgatttt attgattttt aagcgttaat 2580 agaacgaaat ggatatgttt attagttatt ataaatcgaa ttattttata tgagagagag 2640 aaatgtggtt taagttttat atttgttttt taaataatcg atttttttta attttgtttt 2700 taaaggttcg tggaaattag ggagggggtt ggggagacgg ttttagaaat aaaacgtttt 2760 tttttagtac ggtttttata tttagtttat ttaagttgat ttttgtaatt tatataaaga 2820 atgggttcgg gtgggtggtt agtgaagatt ggggtgagta agcgtttacg tcgtcgagcg 2880 tcggggaggt ttaggttcgt tttcgtatag aattttgtaa ggagcgcgtt tcgttaggtg 2940 ttcggattag agggcgttgc gtttttgtaa atttcgcggt ttcgatgcgt tttttttagg 3000 tattattgtt ataataagtt atatttaaaa taatgtataa atagtatcgt tttttaagtt 3060 ttttttaata gtgttttata tgtattttat gaatttttaa agttatgtat acgaattttt 3120 tatcgtcgat tcgtataaag ttagagggat gcgtagtttt tggagtcgag aattcgtagg 3180 gcgtatacgt tttttcgtat tcgtttagag ttatatattt tacgtaattt tattaacgtt 3240 taaatttaaa tgttaaaagg tatgtacgat ttgaataaag aatttattag tttagtcgag 3300 ttttcggttt tgggttttaa agttttcggt agtttcgtga ttttttcgcg gtgtagatat 3360 gtgttaagag tcgggtttga agtattaatt ttgttttttc gggattttta gtatgttttt 3420 aattagagtg ttaacgttcg tgtcgtcggg atttaggcgg tcgtattttc ggaggttttc 3480 gattagggta aatttaagta ttaaacgtag gcgaaaagag agtgcgcggg gtcggaacga 3540 gggttcggga gtagttaagt ttgttaggac gtgtttaggt agttagtcgt cgagttgagg 3600 agttgcggtc gtcggttgcg gcgattcgtt gttttttttt ttattttttt ttttttggag 3660 gcggtggggg aggggaggtg acgttagcgt ttcgtttcgt ttttcgtttc gggcgcggac 3720 gggatttttc ggttgggcgc gttatttcga tagtggtagt agcggtcgtg gaggttgcgg 3780 gggtttcggt ttttgcggtt tttttggtcg gtcgtagttg tggcgcgggt gaaacgttcg 3840 tttttttttt tcggttgcgt ttttcgggcg tcggcgagcg cgggcgtttt tcgtatttag 3900 cgtttggagt cgtttggagt ttcgttgcgc gtattttttc ggttcgcgga gttttttcgg 3960 cggcgttttt tacgtcgcgg attgtaggtg atgttttttt ttttttgtag tcgaaattcg 4020 tcgcgatgtg tcgtttgtta gatttttgtt gggcggaagt atgaatagtt tttgtagatt 4080 ggtttggacg atttgtattt tgtggttttt taatttttgg atgtgaattt ttt 4133 <210> 169 <211> 4133 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 169 aaaaaattta tatttagaag ttggagggtt ataaagtata agtcgtttag gttagtttgt 60 agagattgtt tatgttttcg tttagtaaaa atttggtagg cgatatatcg cgacgaattt 120 cggttgtaga agaggaagag tattatttgt agttcgcggc gtgggaaacg tcgtcggagg 180 ggtttcgcga gtcggggaag tgcgcgtagc ggggttttag gcggttttag gcgttgagtg 240 cgaggaacgt tcgcgttcgt cggcgttcgg gagacgtagt cgaaggagga gggcgggcgt 300 tttattcgcg ttatagttgc ggtcggttag agagatcgta gaggtcggga ttttcgtagt 360 ttttacggtc gttgttgtta ttgtcggggt ggcgcgttta gtcggagaat ttcgttcgcg 420 ttcggggcgg ggggcgaggc ggggcgttga cgttattttt ttttttttat cgtttttaag 480 ggggagggag tggggaaaga ggtagcgagt cgtcgtagtc ggcggtcgta attttttaat 540 tcggcggttg gttgtttggg tacgttttga taaatttggt tgttttcggg ttttcgtttc 600 ggtttcgcgt attttttttt cgtttgcgtt tggtgtttaa gtttgttttg gtcggaagtt 660 ttcggagatg cggtcgtttg ggtttcggcg gtacggacgt tggtattttg gttagggata 720 tgttgaagat ttcggggagg taaagttggt attttaaatt cggtttttaa tatatattta 780 tatcgcgagg ggattacgga gttgtcgagg attttagagt ttagggtcga ggattcggtt 840 agattggtga gttttttgtt taaatcgtgt atgttttttg gtatttaagt ttaaacgtta 900 atgaaattac gtggggtgtg tggttttaag cgagtgcggg gaagcgtgtg cgttttacgg 960 gttttcggtt ttaggagttg cgtatttttt tggttttgtg cggatcggcg atgaaagatt 1020 cgtatgtata gttttgggag tttataaaat atatatagag tattgttaaa aagaatttga 1080 gaggcgatgt tgtttgtgta ttattttgaa tgtaatttat tatagtaatg gtgtttaggg 1140 agggcgtatc ggggtcgcga gatttgtagg ggcgtagcgt tttttagttc gggtatttgg 1200 cgaggcgcgt tttttgtagg gttttgtgcg gaggcgaatt tggatttttt cggcgttcgg 1260 cgacgtgggc gtttgtttat tttagttttt attgattatt tattcgggtt tattttttat 1320 atgagttata aaaattagtt tgggtggatt ggatgtagag gtcgtgttgg aggaaagcgt 1380 tttgtttttg gaatcgtttt tttaattttt tttttaattt ttacgagttt ttggggatag 1440 ggttagggag ggtcgattat ttaaaggata aatgtggaat ttgaattata tttttttttt 1500 ttatataaaa taattcgatt tgtggtagtt aataggtatg tttatttcgt tttgttggcg 1560 tttaaggatt agtagaatcg tggtagagtt ttaagtttga aatttttatt tttggttttc 1620 ggcggttttt gtggcgacga agtgtaattt tttttaggta gatagatttt ttagggagtt 1680 tggaaaatcg ggatttttag atagatgtaa aatatttagt aagttttagg aagcgttatt 1740 atttattaat taatggtaat tttttttagg aatttttttg tgttatttaa aaaaaatttc 1800 gtgattttac gttagggaat ggtatttttg tatttttttt attgtttttt tttttttttt 1860 ttagtattat tttcgttttt tcgtttttag gaaacggttg gagtttcggt gtgtttgggt 1920 tttgttgaga tttataattc ggtaagcggt ataagtcggt tgggtttgga gattaggtta 1980 tttattttcg aggtgtttta tgtatgaaat tgatttgtaa gtatttggag taattatggt 2040 cgggataaat acgtttttgg atgatggagt ttgtatttgt tggatgtgtg aatttatgtg 2100 tattttaatt ggtgggtagg gaatataggg ttacgaatcg gtatatttat tttgtaggta 2160 ttattttttt tttttagtta taatttgtta gatattttta ttattattat ttttttcggt 2220 tatttttaag atggtttata aggtgattgc gttaattttg aatttaggaa attttttttt 2280 atatttgatt gttttgtcgt tttttttttc gttaagtttt ttttattagt tttagggaaa 2340 tcggattttt ttgttttttt agtgttaaaa tgtttgagtt ttataaattt ttcgagatta 2400 agttcgtttt tttgttcggg ttgcgtttta gcgttttcgg tttttcgggt ttcggtcgag 2460 ttcgttttgc gtcgagtttg cggttggagt tttgttcgta tcggggatgg gtttcgcgtt 2520 cgggacgttt aggttgggcg ttcggcgcgg ggagttttcg gagcgggttt ttcggcgttg 2580 gggttttttt tttgtttagg aatttgtagt tgtcggtttg gggttacgtt ttggggtttt 2640 tggggtcgat tttcgggtta ggaagttcgc gggacgtcgc gattgttttt tgttttatag 2700 gtttgggcgt tcggggtgtt agcgggggag gttaggcgtt cgcggcgggg agggtttggg 2760 gtttaattcg gtagaaaaag gtcgcggggg aagcgttttt attttttggg gattgaagga 2820 ggaagtagat ttcgatttag ttgtattttt ttggagattt gaaggacgat tttagtttat 2880 taaattttcg cggatttaga gtcgcgttat ttaaatgtag atttaggggt ttttagaagg 2940 ttatggaaaa gttaaaggga tgtttttggg aagttttttt attaggtttt agtttttttt 3000 tttttttttt ttttttagtt aagttaacgt tttttttttt tggtagggag ttttttttaa 3060 ttttttgtat agcgtttgtg gttggtcgta attaatttcg gtattataag tttcgttttg 3120 tttttcggag tcgcgttaga tttcgttggg cgttttttcg ttttttagta cggatttggt 3180 gttcgtaggg attggggttt tttgggttcg ggcgggattg cgtggtcgag ttcgcggttt 3240 tagagtcggt agtcggggaa agtgggttcg agttttcgcg ttcgagaaat gagcgtcggc 3300 gtcggcgggc ggggtcgggg cggagggatt ttttgcgttc ggggagcgtg aggcgtcggc 3360 gtcgagttgg gcggtcgggc gcggggagag ggcgcgggag cggttcgtgc ggtaggtatt 3420 atgcggacgc gcgagttcgg cgagggtttc ggtaggttcg gtttttgttc gggggcgcgt 3480 tgagacggcg ggtgagtttt acgagagcgt cgtcgttatt tcgggttaat tttgcggtta 3540 gttcgttggg gcgcgggtcg gcgggcgggg gcgagagcgt gtagcgcgtt gcggtgcgga 3600 ttttgtgggt gttcgttcgg ttttcggttc gggtttcggc gttgtcgaaa acggatgagc 3660 gcgcgatttt tcggagggtg gagtgattcg gtttttttta gttgggaaat ttagtattgg 3720 ttaggggggt ttcggcggcg gagcgggaaa aggaggcgat cgcgcgggat cgattcgggg 3780 ttattgttgg ggttcgattt tttttgatac gtcgtttttt tttcgggagt tcgtcgggtt 3840 gcgtcggttt cgcggttttt tggggtattt cgtcgtttgc gaaagattcg ttcgttgagc 3900 ggtgtacgcg ggaggtttgc gcggggttgt cgggtttttg ggtttttggg tgtttgcgtt 3960 ttgtaggagc gttgttcgga ggtgtagatg taatcggtgg attgcggagt gaagggttgc 4020 gaggttgtat ttcggggttg aatatttgta taatgtgcgg tttgttagtg ttttttgttt 4080 tttttggagg aggaattttt aagatttttt taaaagaaag agtttttggt ttt 4133 <210> 170 <211> 4318 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 170 tatatagttt attagtgata gagtaagatg agatttgaat ttatgttatt gatttttagt 60 atagtttata tttttggttt tatagatgaa gaaattggtt ttaggaggga taaatgattt 120 gtttatttta tttaataatt gtgtattaaa tttattttta taagtgtgtt agtaggatta 180 gttttgagta aaaatgaaag tttagtaaag tttaattttt agtatatttt atgtttttat 240 gattattttt attcgtaatt gatatatatt tttggtattt tgttttttag ttattttaga 300 ttatgtaatt ttggtttgga gatttggttt tatttattgt ttttttattt ttagtaattt 360 aagaggtata aaaaaaattt atttttaaat ggttatatat tgggtagggt aggggtaaag 420 agaagtgatt ggttttcggt tggaagaagg tggtttatta tttagttttt ggttattgtt 480 tttttttaga tttagtgtag atatttttag gttggttttt ttattttttt ttattgaggt 540 taattatttt gttttattgt agggttttag gtttttttat ttaaggtttg tttcgttttt 600 ttagtttttt ttttagtagt tttaagggtt tagtttgtgt ttgattattt aggattatta 660 gattttaaag ttgtggaatt ttataatttt tacgagtata tgtttttttt tagggttttt 720 ttacgtttga aaaggcggtt agtagttttt tgttattttt ttatagtagt agtgtaggtt 780 agttgataag gattataaat ttttagtgtt ttatagttgg cgtttagata gtgtgggtga 840 cgggtagaat aagagttttt gaagtaagtt tagaaatttt aataagttga aatgtagtag 900 agattgtaga ggtataagga aagggattag atatttaaat tttgtagggg tttaggaggt 960 tatgttttaa agtttttttg atttttgttt tttagttttt tttagcggtt attaagcgta 1020 aagttttatg tttggttttt aagttattta agtagttttt tttagagatt tgttgcgtgt 1080 tagatatttt gttagaattc gggaatttta ggaatgaaag gaatataagt agaaaaaaat 1140 tagaagaata taaagagttt gtattattta atttttaaga tatttttttt ttttttgggc 1200 gttagtattt agagagtatc gattttagcg ttaaaattcg gttttttttg aggtagatta 1260 ggagttatta cgtttttagt gaaatggagg cggtaggaat tttattttta attttttttt 1320 ttttttttac gattattttt tcgggggcga gagtcgttcg gaagaattat tcgcgtttcg 1380 gtattggttt tttgttgagt tttagtcgga taaaattagt cgattgttta tattaataag 1440 tgttagagtt cgcgtttagt tgagtgggtg gggagagtag tattgggtcg ggtcgtattt 1500 tcgttcgggt ttgttagagt agcggataga tagtatttgt cgtgggtttt ttcgtttttt 1560 tatttttgtt agagtttgtg gttttttcgc ggagatcggg gattatattt gggagtattt 1620 ttttttaatt ttcgttatcg tagagatcgc gtcgagttta tttgttaaat gttaatatat 1680 tggaatgtta ggggagggga aaagaaggtt gtatttttat tttttttttt tattatatat 1740 ttatttttta ttgatttcgt tacgattggg ttttggtatt cgggtttggg ggtgttaatc 1800 gatattattt ttcgttaggt ttttatgttt attttatatt ttgggattgt ttgggggtgg 1860 atttggtttt ggcggtcgtt tttggttttg tcgttggttt tcggttattt tgggcgggga 1920 cgcggagagt ggggttggtt tttttttcgt cgcgggtttt tatttatttt tttatttggg 1980 aggggtaata attcgggagt cgcgttacgg aaatgtattt ttttttgtta tttagacggg 2040 aattcgttta tttatgataa tcgttttttt cgtttaggga aagggggcgg gaagatttag 2100 tttcgggttt tgttaattgt tagtaagtta gacggataga tagtagttgt tgcgtgttcg 2160 agtttagttt tttttcgatt tttcgttttt tatttttttg ttcgttttat cgatattagg 2220 ggtcgtagcg gcgacggcgt tttattttta gcgttcggtt cggagttttc gaggtgattc 2280 gggttgggtt tgtcgaggat tttttataat cggcggtttt ttattttttt tcgatcggtt 2340 tcgtttttag cgttttaaga gcgggattag gcggttgtta gcgaaagatt tataggagtt 2400 tagattcgag gttcgttagg atgcggagat tgagggcggg ttcggtcgtt aggaagcgtt 2460 ttcgttcggg gtagtaattt tttttcgttt ttttttgtaa tttttaattc gggagggttt 2520 tacggggttt ttttttttat atagtgggtt agtttagtgg ggttgttttt tgttaaagat 2580 ttggtttatt ttttaagcgt tttttttttt agtttttata aaaatttttt tagaatttcg 2640 gggaattaat tatgttggtg ggagttttta gtttaggttt atttttttat tttatagttt 2700 tcgattatat aggggagtac gcgggatttt ttaggtttga gaattttttt ttaagtttgg 2760 acggagtttt aagagtggtg agaaggatta gattgattcg aagagtcgtt ttttttagtt 2820 tgtttttttt ttatattttt ttattttagt ttttatcgat ttgttttttt ttgcgtttgt 2880 ttagtggggg gtgaaggaga ggataattat ttttattttt ttttttaatt tttatatata 2940 tttttcgttt tttaaggtgg agttttttgg gaggcgggta gtttcgtaga tttttttgtt 3000 ttaaggtttt gtaaaggtag agtttttttt tgttagtttg gggtttttta gttttttgtc 3060 gtatttgtta ttttttttta tatttttttt attttttttc gtagtatatt tggatataga 3120 ttatttttcg atttcgtaaa aaataaaata aaataaaata aaataaagtt ttgagaaatt 3180 tttaaatatt tgtgcgtgga cgaattatag tttatagttg tttttatatt ttttattata 3240 attggttttt tttttaatcg tgggaggtaa ttgtttttaa gtcgggttat agttggggga 3300 attgaggatc ggggggaatt gaatgtgggt tttgaacgtt tttgtaaggt tttttttatt 3360 ttattttata gaaagtaggg aagtgagtaa attttttatt ttttttgatt ttagaaagtt 3420 tgtttgttgt ttttggagtt agtatttgtt ttttttttgt ttattttatt ttttaatgaa 3480 ggtattattt gggagtggta ttatagtttt aagatggagg tatggagggt agtagaagtc 3540 gagttatagt ttttgtgtat tttttggatt tttttaagga gggtatgtgg aagagaaagt 3600 ttgttttttt ttgggagtat gggttattgt tttttaggtt tttttttttt ttaatatgga 3660 ggaaaaattt taaaataagt ttgcgtgtgt tttatttttt tagttttttt tttatgattt 3720 aataaaatta ttattattga gggttaattt ttagggtttt gtttgatgtt tataggttat 3780 aaaaggaaga attttttggg ttggttattt ggggacggga gggtgaggag tagtttatgg 3840 gaggttttgt tttcgtgaga aaggatttgt atgtttaaga ggttaatata gttagtttag 3900 ggtttttttt tttttagatt tttagttttg tattaggtta tagagaggaa atggtaaaga 3960 gtagtaaata ttatgtaaaa gggtaaagga gtttttaagt taggagttgg gagtttttgg 4020 gaaaagaaaa gggaagaata tgtttaaatt tttgtttata gttgggcgtg gtggtttacg 4080 tttgaaattt tagtattttg ggaggtcgag gtaggtagat tatttgaggt cgagagttcg 4140 agattagttt gattaataag gagaaatttt atttttatta aaaatataaa aaataaatta 4200 gtcgggcgtg gtggtatatg tttgtaattt aagttattta ggaagttgag gtaggagaat 4260 cgtttgaatt tgggaggtgg aggttgtggt gagtcgagat tatattattg tattttag 4318 <210> 171 <211> 4318 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 171 ttagagtgta atggtgtgat ttcggtttat tataattttt attttttagg tttaagcgat 60 ttttttgttt tagttttttg agtagtttga attataggta tgtgttatta cgttcggtta 120 atttattttt tgtattttta gtagagatgg ggtttttttt tgttggttag gttggtttcg 180 aattttcgat tttaggtgat ttgtttgttt cggtttttta aagtgttggg attttaggcg 240 tgagttatta cgtttagttg tgggtagggg tttagatatg tttttttttt tttttttttt 300 aggagttttt agtttttagt ttgggagttt ttttattttt ttgtataata tttgttgttt 360 tttgttattt tttttttgta gtttgatgta gggttggaag tttggaagag aggaagtttt 420 ggattagttg tgttgatttt ttagatatgt aaattttttt ttacgaaagt agagtttttt 480 atgagttgtt ttttattttt tcgtttttaa ataattagtt taaagaattt ttttttttgt 540 ggtttgtggg tattaagtaa agttttggaa attagttttt agtgatgata attttattga 600 attatgagag aaggattgag ggagtggagt atacgtaagt ttattttgga gttttttttt 660 tatgttaagg gggagaggaa tttagaagat aatgatttat atttttagag aaaggtagat 720 tttttttttt atatgttttt tttggggaag tttagggggt gtataaggat tgtggttcgg 780 tttttgttgt tttttatgtt tttattttgg ggttgtagtg ttatttttaa atagtgtttt 840 tattggggga tagagtggat aagggaggag taggtgttga ttttaggagt agtaagtagg 900 ttttttgaag ttagggaaaa tgagagattt gtttattttt ttattttttg tgaagtgggg 960 tggaaagggt tttgtagaag cgtttaaaat ttatatttag tttttttcgg tttttaattt 1020 ttttaattat aattcggttt aagagtagtt gttttttacg gttgggggga gggttaattg 1080 tgatgaggga tataggagta attgtgaatt gtaattcgtt tacgtatagg tgtttggaga 1140 ttttttaagg ttttgttttg ttttgttttg ttttgttttt tgcggggtcg aggggtggtt 1200 tatgtttaga tatgttgcgg ggaaggatga aaggagtgtg ggaggaggtg gtaaatgcgg 1260 tagggagttg gaagatttta gattgatagg aggaaatttt gtttttgtaa ggttttaagg 1320 tagaaggatt tgcgaggttg ttcgtttttt aggagatttt attttaaggg acggagggtg 1380 tatgtgaaag ttggggggag aagtgaaggt agttgttttt ttttttattt tttattaggt 1440 aagcgtagaa ggaagtaggt cggtggagat tagggtagag gagtgtagga gaggagtaaa 1500 ttgaggaggg cggtttttcg agttaatttg gtttttttta ttatttttga ggtttcgttt 1560 aggtttggag gagggttttt aagtttagga aatttcgcgt gtttttttgt gtgatcggga 1620 attgtgagat gggggagtag gtttgagttg ggagttttta ttagtatggt tgatttttcg 1680 gagttttgaa agagttttta tggagattgg gggaaggggc gtttgaaggg tgggttaagt 1740 ttttggtaga aagtagtttt attgggttga tttattgtgt ggaggaggag gtttcgtagg 1800 gttttttcgg gttggaggtt gtagaggagg gcggaggagg attgttgttt cgggcgggag 1860 cgttttttgg cggtcgaatt cgtttttagt tttcgtattt tggcgggttt cgagtttggg 1920 tttttgtagg tttttcgtta gtagtcgttt gatttcgttt ttgggacgtt agggacgagg 1980 tcggtcggga gagaataggg ggtcgtcgat tgtaaaagat tttcgatagg tttagttcgg 2040 attatttcga gggtttcgga tcgagcgttg ggggtggggc gtcgtcgtcg ttacggtttt 2100 tggtgtcggt ggagcgagta gggaggtaga gggcggggga tcgaggagga gttgagttcg 2160 gatacgtagt agttgttgtt tattcgtttg gtttgttggt agttggtagg gttcgaggtt 2220 aggttttttc gttttttttt tttaggcggg aagggcggtt gttatgggtg ggcggatttt 2280 cgtttgaata gtaggggaag atgtattttc gtggcgcggt tttcgggtta ttattttttt 2340 taaatgggga aatggatgga gattcgcggc gggggaggag ttaattttat ttttcgcgtt 2400 ttcgtttaag gtggtcggag gttagcggta ggattaggag cgatcgttag ggttaaattt 2460 atttttaggt agttttagag tgtggagtgg gtatggggat ttggcgggaa atagtgtcga 2520 ttagtatttt taggttcgga tgttagggtt tagtcgtggc gaggttagtg aagggtgggt 2580 gtgtggtggg aaaggagagt agaagtgtaa tttttttttt tttttttttg gtattttagt 2640 gtattaatat ttggtaggtg ggttcggcgc ggtttttgcg gtgacgagag ttggggaaag 2700 atgtttttaa gtgtagtttt cggttttcgc gggggggtta taggttttgg taggagtgag 2760 ggaacgagga ggtttacgat aggtgttgtt tgttcgttgt tttgataggt tcgggcggga 2820 atgcggttcg gtttagtatt gtttttttta tttatttagt tggacgcgga ttttgatatt 2880 tgttagtgtg agtaatcgat taattttatt cggttggggt ttagtaggaa attaatgtcg 2940 aggcgcgggt agttttttcg ggcgattttc gttttcggga ggatagtcgt ggggagagga 3000 agaggggttg ggggtgggat ttttgtcgtt tttattttat tgggggcgtg gtggtttttg 3060 atttgtttta gagaggatcg aattttggcg ttaaggtcgg tattttttgg gtattggcgt 3120 ttagagaaga aaagggtatt ttggaagtta ggtagtataa attttttgtg tttttttggt 3180 ttttttttat ttatgttttt tttatttttg aagttttcgg attttagtag agtgtttgat 3240 acgtagtagg tttttagaaa agattgttta aatgatttga aaattaggta tagaattttg 3300 cgtttggtga tcgttagaga gagttgaaag gtaggaatta aaggggtttt gaagtatagt 3360 tttttgaatt tttgtaggat ttgggtattt aatttttttt tttgtgtttt tgtagttttt 3420 gttgtatttt agtttattag aatttttgaa tttgttttaa gggtttttat tttattcgtt 3480 atttatatta tttaggcgtt agttatgaga tattagggat ttgtaatttt tgttagttgg 3540 tttgtattgt tattgtggag aagtggtagg gagttgttgg tcgttttttt agacgtgaaa 3600 agattttaga ggagagtata tgttcgtaaa aattatggga ttttatagtt ttgaaattta 3660 ataattttgg gtgattaaat atagattgga tttttggggt tgttggggaa ggggttaggg 3720 gagcggggta gattttaggt gggagagttt ggggttttgt aatgggatag agtaattagt 3780 tttagtggga ggagatgagg aagttagttt gagggtgttt atattgagtt tgaggagaaa 3840 taatagttaa gagttgggtg gtaaattatt tttttttaat cggaaattag ttattttttt 3900 ttgtttttgt tttgtttagt atgtggttat ttggagatgg attttttttg tattttttga 3960 gttgttgggg gtggagggat agtaggtgaa attaggtttt taagttaaga ttgtatggtt 4020 tggagtgatt gggagataga atattaaaag tatgtgttag ttgcgggtga gagtaattat 4080 gaagatatgg ggtatgttaa aagttaaatt ttgttaaatt tttatttttg tttagagttg 4140 gttttgttga tatatttatg gaaatgggtt tggtatatag ttgttgaatg aagtgggtaa 4200 gttatttatt ttttttaggg ttagtttttt tatttgtaaa attaggggtg taaattgtat 4260 tggaagttaa tgatatgagt ttaagtttta ttttgttttg ttattgatga attgtgtg 4318 <210> 172 <211> 3324 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 172 tttaatttta atttttttat aggaataatg ttaattagcg aggtttaatg agaatttttt 60 ttaggaagcg tagttcggta ggggcggtcg gattcgggta aacgtagttt cgggtgggag 120 tagggttatt tttgttttcg agcggttgga ataaaaatgc ggattgtatt tttttttttt 180 ttttatttaa agtgtttagt tttgaagata aggtggaggg aggagagaga gggcggaggt 240 gtaaatttaa tttaattttt gcgcgcgttt tcgaggcggt cggttgtttt cgtttcgtcg 300 tgttttttta ttaaggaagg ttttttcgtt aggggtcgtt aacgttcgcg gttttcggtt 360 agacggtgta tttgagaggg atatttcgtt ttttttcggg agggattcgg gtttgttgaa 420 gtgggtttaa ttttgtaaat cgcgttttaa tttttcgcgt cgcgtcgggg aatttttttt 480 tgatatttaa cgtttttcgt ttttatattt ttaaatatag tttatttttt ttttcgtggc 540 ggtcgcggta attcgagttc ggttttcgtt tcgtcgttag agaacgtttt tttcgtcggg 600 acgcggtgtc gagttcgttg tatatcgagc ggtcgtggta taatatcgcg gcgttgcgcg 660 tataattatc gttttttagg attcgcggcg cgtatttcgg gagtggggtg cgtttcgcga 720 ttttgggcgt ttagggttag atatattttt tgggcgtttc gcggttttta tagtgtagtt 780 tttatcgttt tttttttatt ttcgggtata tttattcgtt tttcgtttta gtttattcgg 840 tttagggcgt agtcgttttt tcgcgttttt ttttttagtt tcggtaaagg aagttttttt 900 tgcgtttttt tttttagaat cgtttttagt ttttcgtttt tttaatcgta gtttaacggt 960 cggcggtagt agtcggagaa ggggggcggc ggttcgggtt tcggaaacgg ttcgatcgtc 1020 gggattcggg tcggatttcg tatttgggtt ggaagcgagg cggagatggg cggtcgggat 1080 tcgcgagtga gcggggcggg cggcggtgat agttttatag ttttagttgt tgttgttgtt 1140 gttgtcgtcg cggttgttcg gggagagggg ttggtattat cgcggcgcgt tattgttcgg 1200 ttcgggggcg ggggtggtta ggaggagggt ttaggcgagt agcggcggta gcggcggcgg 1260 cgtcgcggtt cggaggaagg gggagggggt atcgggtacg gggaggcggg agagggggcg 1320 ggatcgggta cggggcgggg gcggggggga ggggagcgta gggagggcgt aggtaggggg 1380 agtaggagga gtagtaggag gaggtggcgg aggggcgggt gagagggagg agtgggtacg 1440 gggggaaggg gagagaggaa aaggaggtat ttagggagag gggagaggag aaaggaggga 1500 gagaggcgcg gggggagaag aggaggaagg agggggagtt gggttaggta gggggggata 1560 agggcgcgtt ggacgcgtcg tcgtgcgttt cggtggggag cgcgttttta agggggaagc 1620 gtttcgagga agatttttgt acggggttga gttcggaaag aaggcgttgg gatttgtgtt 1680 tatttatcgt tttcggaggt tgcggttttt gggttcggtg ggggttgggg ggagagggta 1740 ttcggcgggt tgtttgcggt taggttagga gagggagatt tggtttaaat aaagtgattt 1800 aggtattttt aggaattttc ggcgttcggg gttttttcgg gtagttttcg atttttatgc 1860 gtttttcggg tttttaggga cgcgggtatt tgtggggcgg ggttgtcggg tttcggggtt 1920 cggttttttc gggcggtcgg agcgagattt cgggttggga aagttaggta cgtggtcggt 1980 tttcggtcgt attttcgttt tatttttacg gtagggtttt tagtgtttga ttaagtttaa 2040 gttcgagttt ttcggcgcgt tgtttatcgg ttgttttttc gcgttttttt ttttttttta 2100 ttcgtatcgt ttcgtttttt attttttttt tgtttttttt ttattattta gtttatattt 2160 ttttcgtttt ttttttcgtt tttcgcgggt attcgagtgt tcgggaggcg tttatttgtt 2220 cgatttaaat atttacgcga tttttagcgt tcgtcgttcg cgtgttcgtt ttcgtttcgt 2280 cgtcggttat tgtgtttcgt tagtttatat cgggtcgggt tttgacggcg cgcgagttat 2340 agttgtaaag taataggata atttcgggga cgtcgtttta gtttagattc gggtacgtat 2400 tgttcgtgga gacggtatcg tcggggaggg gagttacgcg gattttagat gcggtttttt 2460 aggcggatag atttttgttc ggggcgtagg aggaggtagg attggtatcg cggggtggga 2520 gttttggatt ttcgagtaat ttcggattcg gttcgaaaag taatattttt attattaaat 2580 cgtagaatta gatttcgatg gagaaaatgg gttaggggat ttatttttat tttatttttt 2640 taaatttaga tttttcgtta ttatagatta gtttcgaaaa aagtttgtgt tttaataagg 2700 atggggaatt gttttcgtgg aattttgtgg ggaaattgtt aaaaaaaaaa aaaaaaaaaa 2760 aaaaaaaaat aattaaaaaa aaattttgat aaggatttta ttttttgatt tttttggtcg 2820 tattcgaaga ggaagggtaa tttttattga ttttttacgt tattatttat ttacggtgga 2880 attagtagag aagagaaaac gagatagtta tagcgattgt ttgtaatttt gaaatagatt 2940 gtttttaatt ttttaatttt ttttttgtaa aaagtttttt tttttttttt ttttgaaagt 3000 tttgtattgt gaataattta tggtaaataa ggtttttttt atagtcgcga gtgcgaagta 3060 taattttata ggtttagagt ttagcgttta ttcgttagaa aaataaaatg atgataagat 3120 attatattag cgttacgtag gttttttttc gtatatgttt aagattttgt tgttaataga 3180 aaatttatat ttttttttta aaagagggtt taggtatatt tatttatttg tattttttat 3240 ttttgaaatt aaatgtgttt ttaaattaat ttattttttt tagtttattg gattttttta 3300 tttttggtga tgtggggtag gtgg 3324 <210> 173 <211> 3324 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 173 ttatttgttt tatattatta aggatgagaa gatttagtaa attggggaga gtgaattggt 60 ttgaaaatat atttgatttt aggaataaaa ggtgtaaatg agtaaatgtg tttaaatttt 120 tttttaaaaa gaaagtgtga gttttttatt gatagtagag ttttgagtat gtgcggaagg 180 aagtttgcgt ggcgttaatg tgatgttttg ttattatttt atttttttga cgggtaaacg 240 ttgggttttg aatttgtggg gttgtatttc gtattcgcgg ttgtagaggg agttttgttt 300 attatggatt gtttataatg taaagttttt agaggaagaa agaaaaaagg ttttttatag 360 aaaaaaagtt ggagggttaa aggtagtttg ttttaaaatt gtaaataatc gttgtggttg 420 tttcgttttt ttttttttgt tggttttatc gtgaatgaat ggtagcgtaa agagttagta 480 gaaattgttt ttttttttcg gatgcgatta gaggaattag gaggtgggat ttttattagg 540 gttttttttt agttgttttt tttttttttt tttttttttt ttttggtaat ttttttatag 600 aattttacga gggtagtttt ttatttttgt tgaagtataa gtttttttcg aggttgattt 660 gtggtagcgg agggtttgga tttggagggg tggggtggga atggattttt tgatttattt 720 tttttatcgg ggtttaattt tgcggtttgg tgatgagagt gttgtttttc gggtcgagtt 780 cgaggttgtt cggaggttta gggtttttat ttcgcgatgt tagttttgtt tttttttgcg 840 tttcgggtaa gggtttgttc gtttggggga tcgtatttgg aattcgcgtg gttttttttt 900 tcggcggtgt cgtttttacg gatagtgcgt gttcgggttt gggttggagc gacgttttcg 960 agattatttt attattttat aattgtggtt cgcgcgtcgt taggattcgg ttcggtgtgg 1020 gttggcggag tataatgatc ggcggcgggg cgggggcggg tacgcgggcg gcgggcgttg 1080 ggggtcgcgt agatgtttgg gtcgaatagg tgagcgtttt tcggatattc gggtgttcgc 1140 ggggggcggg gaggagggcg gagggggtgt aaattaagtg gtgggaaaga gataaaggaa 1200 gagtgaagag cgagacggtg cggatgggga agggggaggg gcgcggaggg gtagtcggtg 1260 ggtagcgcgt cgaggagttc gagtttgaat ttgattaagt attgggggtt ttgtcgtggg 1320 ggtggggcgg gggtacggtc gagagtcggt tacgtgtttg gtttttttag ttcggggttt 1380 cgtttcggtc gttcggggga gtcgaatttc gaggttcggt agtttcgttt tataagtatt 1440 cgcgtttttg gggattcgaa agacgtatgg gggtcgaagg ttgttcgaag gggtttcggg 1500 cgtcgagagt ttttgagggt gtttgagtta ttttatttgg gttaagtttt ttttttttgg 1560 tttgatcgta gatagttcgt cgggtgtttt ttttttttag tttttatcgg atttagagat 1620 cgtagttttc gggagcgatg ggtaggtata gattttagcg tttttttttc gggtttagtt 1680 tcgtgtaagg atttttttcg aagcgttttt tttttaagag cgcgtttttt atcgaagcgt 1740 acggcggcgc gtttagcgcg tttttatttt tttttatttg gtttagtttt tttttttttt 1800 tttttttttt ttttcgcgtt tttttttttt tttttttttt tttttttttt ttgggtgttt 1860 tttttttttt tttttttttt ttttcgtgtt tatttttttt ttttattcgt tttttcgtta 1920 tttttttttg ttgttttttt tatttttttt gtttgcgttt tttttgcgtt tttttttttt 1980 tcgttttcgt ttcgtgttcg gtttcgtttt ttttttcgtt ttttcgtgtt cggtgttttt 2040 tttttttttt ttcgggtcgc ggcgtcgtcg tcgttgtcgt cgttgttcgt ttgggttttt 2100 tttttggtta ttttcgtttt cgggtcgggt agtgacgcgt cgcggtggtg ttagtttttt 2160 ttttcgggta gtcgcggcgg tagtagtagt agtagtagtt ggagttgtgg ggttgttatc 2220 gtcgttcgtt tcgtttattc gcggatttcg atcgtttatt ttcgtttcgt ttttagttta 2280 ggtacggagt tcggttcgga tttcggcgat cgggtcgttt tcggggttcg ggtcgtcgtt 2340 tttttttttc ggttgttgtc gtcggtcgtt gagttgcggt taggggggcg aggggttggg 2400 ggcggttttg gggagggggg cgtaggggga gttttttttg tcggggttga gggagggggc 2460 gcgggggagc ggttgcgttt tgggtcgagt gggttggggc ggggggcggg tgagtgtgtt 2520 cgagagtgga gggggggcga tgaaggttgt attgtggggg tcgcggggcg tttaagaggt 2580 gtgtttggtt ttgagcgttt agggtcgcgg ggcgtatttt attttcgggg tgcgcgtcgc 2640 gggttttggg gggcggtgat tgtgcgcgta gcgtcgcggt attgtgttac ggtcgttcgg 2700 tgtgtagcgg gttcggtatc gcgtttcggc gagggaggcg ttttttggcg gcggggcggg 2760 ggtcgggttc gggttgtcgc ggtcgttacg agaagggaag tggattgtgt ttggggatgt 2820 gaggacggga agcgttgagt gttagggagg ggtttttcgg cgcggcgcgg ggagttgaga 2880 cgcggtttgt agagttgagt ttattttagt aggttcgggt ttttttcggg aggggacggg 2940 gtgttttttt taggtgtatc gtttgatcgg aagtcgcggg cgttggcggt ttttggcgaa 3000 ggggtttttt ttaatgaggg gatacggcgg ggcgggggta gtcggtcgtt tcgagggcgc 3060 gcgtaggggt taagttggat ttatattttc gttttttttt tttttttttt attttgtttt 3120 taaggttgga tattttggat agggaggagg ggggagtgta attcgtattt ttattttagt 3180 cgttcgggag tagaagtgat tttgttttta ttcggagttg cgtttgttcg agttcggtcg 3240 tttttatcgg gttgcgtttt ttgggggaag tttttattaa gtttcgttaa ttagtattat 3300 ttttgtagaa aggttaaggt taga 3324 <210> 174 <211> 4431 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 174 ttatagttaa tgtttaatat tttaattttt ttaggtttag aattttttta ggattgattt 60 tgtgtttatt tgtgttaaaa tgtgttaaat tagataggaa ggggaagtat aaaatttaat 120 ttataattta aggtaagaat ttgagttttg gtttgaaaaa tgaaaagtta tggagtgata 180 taatatattt cgatttttta aataattaag atatttaatt ttaaagatat tttttaaata 240 agagatagtt taagtttaga ttgtttatag ggtattagtt tttagaaaaa tgttatggtt 300 agagatagat ttgaaatgga gatacgtttt aagtttagag ttttggagtt attattagat 360 agtatgttag gagaagataa cgagaaaaag gagagattta tattaatttt gttttatttt 420 tttttcggag gtatatagtt ttgggttgat ttttgggatt agttgattta ttggttgtgt 480 ttttttggtg ttcgtcgttt gtttggaaag gtagttgttt gttgaagagg aaaagttggg 540 aacgtaattt ttaattttta ggataacgtt tagtattatg ttttattttt aatttgtttt 600 ttttaaacgg aaatagataa ggttattttg aaattattta gttatttatg aaatagagtt 660 tataattatt tttttttttt ttttaatacg attagaaggg tgatttttta aatgcggttt 720 tttttatagt tacgttcgga ggggtatttt ttagtgtttt agtaagtgtt tttagcgata 780 ttagaatgtt agttaagatt taagatatat ttttttagtt gtttttcgtt atttgttata 840 gaaaataatg ttgttgtacg tttttaaaac gtcgttttat aagtagattt ggtttttagt 900 aattggtgag gaaaagttat tggaattaaa tattatttat atagttattt agagcggagg 960 ttatcgtttt atttcggtag aggtatatgg gggtagtagg taggatcgag aggggttcga 1020 aggcgtcgta ggaggagagg ttgggcgtag acggttcggt tttaaattat atttagcgtt 1080 aggaaacgta aggttcggga cgaattttta agaagtcgtt gttagggata gggaggttgg 1140 gagtagggag tgacgttata ggaattttga attttttcga gttttttttt aattaagtta 1200 aggtcgagta aggggcgttt tatgtatcgt aagtttttaa tttaatattt cggtaacgat 1260 aaatagaatt tttcgatttt aaaggtcgtg aagtacgcgt ttttcggggt tttgagtgag 1320 tttttaaatt ttcgtgtcga ttttttaaat ttatttttcg tttttttgga atgggcgtac 1380 gcgaggtacg gattttagga aatttttgtc gtgatagttt atttacggtg gaggcggagg 1440 tttgggacgt tggacggaga aaggcggtta gtggagggag gaggggtagg tcggtaacgc 1500 ggtggtttcg gacgttcgag ttgttcggac gaagcgttgg ttttattttc gtttttggtc 1560 gtcgcggtga ttttattcga gtcgtgattt tttttaagat tttagggttc gggttttttc 1620 gttgcgtcgg ttttagggtg ttattttcgg acgtttagat gcgttttgga ttttgcgtcg 1680 ggattttgaa tatcgtcgcg tttttatttc gcgtcgagcg cgttcggttt tgtttcggtt 1740 gtagcgggta cgagttttag gcgggcggcg gggacgtagc gttcgtagtg cgattggcgt 1800 agtcgttgag gtacggggcg cgtcgttcgg atttcgattt cgcggcgtta ggagaggcgc 1860 gggcgtcggt tggagagtcg tatttttcgt ttcgtcgagg ttgttggtta cgggcgcgtt 1920 cgttttaagg gtcgggcgga ggatttgttt cggattttag aggacgtggg tggggaaggg 1980 ataaggatag ggataaggga ggggacgcga attgggtcga ggtgtgggtt agttttggtt 2040 cgggaaggga ggtcgttggt agggttatta ggattttttt tggatatgga aggacgggtt 2100 tgttttggat ttagggattg ggaaatgtgg gtttttttag aatttgggga agtggggaga 2160 gggtttgttt tggagtgcgg agggagattt atttcgggtt taggataatg ggggtggggg 2220 taggacggga atgagggggt atttttggtg tagggagggg agacggagaa gtagtagggg 2280 gtttgtttcg ggttcgcggg ttggggatta cgaagtgtag gagggtatcg tttaggatcg 2340 ggatgaggag ggagaggggt tcgttgtggt tttggataga gggggaggga aagtgcgttt 2400 cggttcgaga ggaggagtag gagggttagt tttggattcg ggtttaggaa gtcgggaggg 2460 aggttcggat tcgttttaga gatagggcga tgaagatttg tttaagtttt ggagtggagg 2520 gaaggatgtc ggcggtgggg gaagaggtcg gttacggata gggaaaggga gttcgttttg 2580 tagggcggac gggcggtttt ggggaaggga gaggtcgcga cgcggggggc gttcggttcg 2640 agcggggtcg tttattttgg gtttgtagag ttattttcgg aatttgttta ttatcgtcgc 2700 gtcggttttg gtcggatttc gggcggtttt cgtttttcgt agcgttgcgt tcgggttcgg 2760 ttgaggcgcg gggcggacgc ggaggtacgg tcggagtttt cgcgttgtcg tagggaggtt 2820 ggttagcgaa gttcggagcg tcgagcgggc ggcgggtagg tgcgcggggt aggtgcgcgg 2880 ttttgagtat gttttgtaag cggcgcgtcg ggtagatttt agattcggga gtgggcgttc 2940 gggcgtacgg atagacgcgg gtacgggggc gcgcggtttt tcgttgttta ttgatattta 3000 gcgtttcgtt ggttacggtc gtttcgcgtc gtatatgcgt ttagggcgtc gcgagtttcg 3060 ggtttatcgc gcgttgcggg cggggcgggc ggggcggagg cggtttaatt tttgcgcggg 3120 cgtcgtattt cgttcgaggc gcgttttttg tcggcggggc gattcgtcgc gttcgggtat 3180 ttaagaaatt ataagtttcg aaaggtatgg cggggaggtg gcgtttaggg tttggcgttt 3240 cgggtcgcgt cgcggcgttg tgtattgtgg gagttgtagt ttattcgatg gcggcggagc 3300 gtgtcgtcgg ttgttaggtg acgacgttaa atagtcgcgg cgttttgttt atcgggagtt 3360 gacggacgac gattgttaat attttagttt tagttggttt aggaaattgt tgcggtggta 3420 ggtggcggcg gtaggagggt tcggttgttt cgagcgttcg ttaggtacgg gggcgggata 3480 ggtgcggggc gacgcgtcgt cgatttttat gatttgtcgg tcggtttttt ttcgttcgtt 3540 gtttattttg ttttttttaa atattttttt tgtttttttt ttagtttttc gatgaaagtg 3600 aacggtgttt tttttttttt ttttaaatta ttattattag cggtgcgttt taaaaagata 3660 ttttttcgtt ttcgttattt tttttagtgg tgttttaatt tgtattttaa aacgtttatt 3720 ttaatttgag tatttgttat gtgttaagta gagagttaaa aatttatacg tggttttatt 3780 taaatttttt attgatagtt agagaagtag gtataacgag gtcggcgtgt tttggttgtg 3840 ggggttgtat ttagattacg gcggatttgg gtcggtttga ttttatagcg ttgtattttt 3900 ttttgtcgta ttattattac gtttttggtt tgttgtgaaa cgtgtagatg taagatatag 3960 gagatggaag ttatgttttt ttcggtttag aattgagaag tttgatttgt ttttgtttgt 4020 ttttattggt tagtgttagg tgtttagaaa ggttcgtggg ttttatgatt attttatttt 4080 aatagacgcg atgtgagttt aggcgcgttg gtatttaaga ttttttttag ttgggggtag 4140 ggtttatgtt tatttttgag taattgattg atttttttta tttttttttt tttattattt 4200 agtcgatttt ttgaagggta aaattttttt ggagtttttt tttattttta attttttttt 4260 atttgttttt tttggaaatt atttttatta gatttttatt taattatttt tttgaagttt 4320 tttattaaag ttatttttga ttttgatgtt gtaaaattcg atgatcgggg ttagcgttta 4380 tttttttttt gaattgttat tattacgtga tttagtcgat tgtgtttttt t 4431 <210> 175 <211> 4431 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 175 gagagggtat agtcggttgg gttacgtggt agtgatagtt taaggaagag atgagcgttg 60 atttcgatta tcggattttg taatattaag gttaaggatg attttgataa agagttttag 120 aggagtggtt gggtgaaaat ttgatgggag tagtttttag aaagaataag tgggaaggaa 180 ttggagataa ggggaaattt tagaggggtt ttgtttttta gagggtcgat tgggtggtag 240 gaagaggaga gtagggaaaa ttaattagtt atttaaaaat aaatatggat tttattttta 300 attaagagaa attttagatg ttagcgcgtt taggtttata tcgcgtttgt tggaataaag 360 tggttatgga gtttacggat ttttttgagt atttggtatt ggttagtgag gataagtagg 420 aataggttag attttttaat tttgaatcga ggggggtatg atttttattt tttgtgtttt 480 atatttgtac gttttataat aagttagaga cgtggtggtg gtgcggtagg gaaaagtgta 540 gcgttgtggg gttaggtcga tttagattcg tcgtgatttg gatgtaattt ttatagttag 600 ggtacgtcgg tttcgttgtg tttgtttttt tggttgttaa tgggaagttt aagtgaggtt 660 acgtgtgggt ttttagtttt ttgtttgata tatagtaggt atttagattg aggtgagcgt 720 tttaaggtat aaattagggt attattgggg ggagtagcga gggcggaaga gtattttttt 780 agaacgtatc gttgatagtg gtgatttaaa aaaaaaaaaa gaggtatcgt ttatttttat 840 cggggagttg ggaagaagat agaagaggtg tttgggagaa gtaagatgag tagcgagcga 900 gagggaatcg gtcggtaggt tatgaaaatc ggcggcgcgt cgtttcgtat ttgtttcgtt 960 ttcgtatttg gcgggcgttc ggggtagtcg agtttttttg tcgtcgttat ttgttatcgt 1020 agtagttttt tgggttagtt ggggttaagg tgttggtagt cgtcgttcgt tagttttcgg 1080 taggtaggac gtcgcggttg tttggcgtcg ttatttagta atcggcggta cgtttcgtcg 1140 ttatcgggtg gattataatt tttataatat atagcgtcgc ggcgcggttc gggacgttaa 1200 gttttgggcg ttattttttc gttatgtttt tcgggatttg tagttttttg gatattcggg 1260 cgcggcgggt cgtttcgtcg gtagggagcg cgtttcgggc ggggtgcggc gttcgcgtag 1320 ggattgggtc gttttcgttt cgttcgtttc gttcgtagcg cgcggtgggt tcggggttcg 1380 cggcgtttta ggcgtatgtg cggcgcgggg cggtcgtgat tagcggagcg ttgggtgtta 1440 gtgagtagcg aggagtcgcg cgttttcgtg ttcgcgtttg ttcgtgcgtt cgagcgttta 1500 ttttcgggtt tgaggtttgt tcggcgcgtc gtttgtagag tatatttagg gtcgcgtatt 1560 tgtttcgcgt atttgttcgt cgttcgttcg gcgtttcggg tttcgttagt tagttttttt 1620 gcgatagcgc gggggtttcg gtcgtgtttt cgcgttcgtt tcgcgtttta gtcgggttcg 1680 ggcgtagcgt tgcggagggc gagggtcgtt cggagttcgg ttagggtcgg cgcggcgatg 1740 atgaataggt ttcgaaagtg gttttataaa tttaaggtga gcggtttcgt tcgggtcgga 1800 cgtttttcgc gtcgcggttt tttttttttt taggatcgtt cgttcgtttt ataagacgga 1860 tttttttttt ttgttcgtgg tcggtttttt tttttatcgt cgatattttt ttttttattt 1920 taagatttgg atagattttt atcgttttgt ttttgaggcg gattcgaatt tttttttcgg 1980 ttttttaagt tcgggtttag gattgatttt tttgtttttt ttttcgggtc ggggcgtatt 2040 tttttttttt ttttatttag ggttataacg ggtttttttt tttttttatt tcggttttgg 2100 acggtgtttt tttatatttc gtggttttta gttcgcgggt tcggagtaga ttttttatta 2160 ttttttcgtt tttttttttt gtattaggaa tgttttttta ttttcgtttt gtttttattt 2220 ttattgtttt gggttcggaa tagatttttt ttcgtatttt agaatagatt ttttttttat 2280 ttttttaggt tttgagagaa tttatatttt ttaatttttg ggtttagggt agattcgttt 2340 ttttatgttt agagaggatt ttgatggttt tgttaacggt tttttttttc gaattaggat 2400 tgatttatat ttcggtttag ttcgcgtttt tttttttgtt tttatttttg tttttttttt 2460 atttacgttt tttggaattc gggataggtt tttcgttcgg tttttggggc gagcgcgttc 2520 gtggttagta gtttcggcgg ggcgggaggt gcggtttttt agtcggcgtt cgcgtttttt 2580 ttagcgtcgc ggggtcgggg ttcgggcggc gcgtttcgtg ttttagcggt tgcgttagtc 2640 gtattgcggg cgttgcgttt tcgtcgttcg tttggggttc gtgttcgttg tagtcggagt 2700 agggtcgggc gcgttcggcg cgggatgaag gcgcggcggt gtttaggatt tcggcgtagg 2760 gtttagggcg tatttgggcg ttcgagggtg gtattttggg gtcggcgtag cggggaggtt 2820 cgggttttga gattttgggg gaggttacgg ttcgggtggg gttatcgcgg cgattaaggg 2880 cgggagtggg gttagcgttt cgttcgggta gttcggacgt tcgaggttat cgcgttgtcg 2940 atttattttt ttttttttta ttggtcgttt tttttcgttt agcgttttag gttttcgttt 3000 ttatcgtggg tgagttgtta cggtagaggt tttttgaaat tcgtgtttcg cgtgcgttta 3060 ttttaggaag gcgggaggtg ggtttggaag atcggtacgg aggtttgagg gtttatttag 3120 ggtttcgaag ggcgcgtgtt ttacggtttt tgaggtcggg gaattttgtt tgtcgttgtc 3180 ggagtgttgg gttgagggtt tacggtatat ggggcgtttt ttgttcggtt ttggtttgat 3240 tgggagggga ttcgggggga tttagggttt ttgtggcgtt attttttgtt tttaattttt 3300 ttgtttttag tagcgatttt ttaagggttc gtttcgagtt ttgcgttttt tggcgttggg 3360 tgtggtttgg ggtcgagtcg tttgcgttta gttttttttt ttgcggcgtt ttcgagtttt 3420 tttcggtttt gtttgttgtt tttatgtgtt tttgtcgggg tagggcggtg gttttcgttt 3480 tggatagttg tatgaatggt gtttggtttt agtgattttt ttttattagt tattgaaaat 3540 taagtttgtt tgtaaaacgg cgttttgggg gcgtgtagta gtattatttt ttgtgataaa 3600 tggcgggagg tagttggaga aatgtgtttt aggttttaat taatattttg gtgtcgttga 3660 aggtatttgt tgggatatta ggggatgttt tttcggacgt ggttgtggaa gaggtcgtat 3720 ttgggggatt atttttttaa tcgtgttgaa aaggaaggaa aaataattgt agattttgtt 3780 ttatgagtag ttgagtaatt ttaggatggt tttgtttgtt ttcgtttagg gaagataggt 3840 taaaggtaga atatggtatt agacgttgtt ttgagaatta ggaattgcgt ttttaatttt 3900 ttttttttag taggtagttg tttttttagg taggcggcgg gtattaagag ggtatagtta 3960 gtgaattagt tgattttagg gattagttta gagttgtgtg ttttcggaga agggatggaa 4020 taggattgat gtggattttt tttttttttc gttgtttttt tttggtatgt tgtttggtag 4080 tagttttaga gttttggatt tgagacgtat ttttatttta gatttgtttt tggttatagt 4140 atttttttgg gagttggtgt tttgtgggta gtttgaattt gggttgtttt ttatttgaga 4200 aatgtttttg gagttaaata ttttgattgt ttgaagggtc ggagtatgtt atgttatttt 4260 atagtttttt attttttaaa ttaaagttta gatttttgtt ttggattatg aattgaattt 4320 tatgtttttt ttttttgttt aatttaatat attttggtat aaataagtat aaagttagtt 4380 ttgggaagat tttgggtttg gaagagttga agtgttaaat attagttgtg g 4431 <210> 176 <211> 3357 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 176 tgaaatttaa atataaaatt cgttaataag gattaattgt atgtgtataa tttaaatttt 60 atttataaat ttaattatat tatttgattt tattagaatt aggttttatt ttatttttga 120 ttttgtttat tatttattta gtatttttgg taataggtgt ttgagcgttt ataggtggtt 180 tttgatttgc gaaagatttc gcggcgtttt tagttagggt ttagggtcgg gtagtttagt 240 tagtttttag ttatggaggt tataggaagt agtagtagtt tgaaaggggg tggaagggat 300 gagggaaatt gaggttttag gaagggataa tattgtgttt taggttatat aaattattgg 360 tatttattag tgtttgttta agttttagga tttgttatag gtaattagtt tatatatgga 420 aaagaaattt tttatatttt tattttattt ttttttattt tgggtttagg atattattat 480 tttttaattt aaggattttt gttttttatt tttagtgttt taatttttta ttttttttta 540 tttttagatt gataatttat tatttttttt tattgttaat ttagaaattt tttatttttt 600 ttttttattt ttttttgtta ttgatttaag ggtttttatt tttttatttt attattttaa 660 gatttttata gtttttattt ttagttttaa agggttttat tttttttgtt tttattattt 720 gattttagta gttttttatt tttttttttt ttgatttagg agtttttaat tttttttttt 780 tagtgtttta attattttat tttttttttg tttgatgttt ttttattttg ttattttagt 840 gttataattt cgattttttt tgcgagatat aattgtttta atttatagtt tgaatagttt 900 tttatttttt ttatttttta tattggaagt tttttatgtt tttttttttt tagtttaaga 960 tttttttttt tatttttttt tttttttaat gtttttattt ataatttttt tttagtttga 1020 gtttttaaat ttttttttat agttaaaaag ttttttattt ttttttttta ttgtttttat 1080 tttttatttt ttttttatta tttagagaga ttttaatttt tttttttagt atttcgaatt 1140 tttttttatt ttttttgttt ttgtttcggg attatgttat ttttaattgt tattattttg 1200 attttttatt gtttttcgtt ttttatatgg ggttttttat tttttttttt tagtatttta 1260 aagtttttat tttttttgtt attagtttga gggtttttta tttttttttt ttagagtttt 1320 gaatttttat ttttttttta attttagatg tttcgatgtt tttttttagc gttttgattt 1380 ttattatttt ttttcgtttt cgttttagga tttcgatatt tttatttgtt agagtttaga 1440 gttgtatttt ttttcgtttt tagtttaaat ttttttattt tttttcgtta gtatttcgac 1500 gtcgttattt ttttttttta tcggtttgag ggttttttat tttttttcgt tagcgttttg 1560 agttataatt tttttttatt tttcgtttga gcgtttttta cgtttagttt taaggttgtt 1620 ttattagttt ggtattaggt cggtattttt cgttatttta ggttcgtgga tttatggcga 1680 gggttttttt tgtatttttc gtttcgtttt tttttttttt tttttttttc gcggtcgttt 1740 tttttgaagc ggtagttgtc gttttcgcgg ttgttcgttg ttttcggaat cggaagttcg 1800 ttgtttgttt ttcgggtttc gtttttggtt aagtatttgc gtattattgt ttcgatgtcg 1860 cgtgttttta atagggaggt tttcgcgttt acgggtcggc gtttcgtagc ggtgcgcgcg 1920 tttttttgtc gagagttagt tgtatttgcg tgttgacgtt taacgatagt taattttttc 1980 gagggattgg tagttgcggt ttttttcgtt gtttatttag ttggcgtatg cgttttttag 2040 ttttaatttg aagggaagcg gtcggggagg gtttgcgttt gcgttttttt ttttttttcg 2100 cggtttttat agtcgatatc gaacgcggta aggaagttgt ttcgcgtttg cgtatttttt 2160 ggttttgtcg gcgttttttt tttttatttt tcgttggggt ttattttgtg ttcgtgggtt 2220 ttttcgaata ttaattttag ggggggtcgt gtttcgtttt ttttttttcg tcgaatagtt 2280 gtgggagcgc gcggggcggg gaaaggggcg gtgttatatc gtaggtaaat tgaggtacgc 2340 gggagggcgc gtttttgtag gaggcggatt tttaacgtgg ggtttgtggg gaaaaggcgg 2400 ggtttggcgt ttatagcgga cgatagtttt gggtgggaga taggagtatg tatgggcggt 2460 gttattatat tgaaggcgcg ttgcgtagat tttttgttcg tgggaggttg ggaatgtggg 2520 tttttgggtt ttcgcggggt gtaggcgttt tttattttat ttagaagttt ggaatagttg 2580 taatcgtagt aatgtggaga tagttttttt ggttttttta aaattttatt aataaaattt 2640 agggagagga ggtaaggatg agtggatttc gtagttttat taggtattga atatgtcgac 2700 ggggatagtt tttttgataa aggtagatgg gcggttaatc ggtggatggg tatagggaga 2760 atcggagaaa tagatgagtg gaggaacgga tatacgggta tcgggcggtt tttttatttg 2820 gaatgtaggg tgtaaggggt tcgggttagg aggtttagcg gtcggtattg gagcgtaggt 2880 cggtagtgag gggatcgtgt tggatcgttt ggtgtagtat tagggttagt aatttcgcgc 2940 ggtttgttat ggttgtgcgt atattgcgtt tttgtttaaa tagttcgttt agtttgtatt 3000 attgttaagg gagcggtagg agttttaagt aggaatattt gtagtttcgt ttgtttcggt 3060 tacgttcgat atggaaattt attatatgta gtattaaaat cgtatagaaa tttattatac 3120 gtacgcgttt taagtttatt ttcgtacgtc gtagtttttt ttagtagtaa tggcgattgt 3180 attggcgttt gggtaggcgg tagaagttat tcgtgagttt aaagatatta cgtataaggg 3240 ggtattcgta tatttcgtta gttggtattt gtaaggaggt taggttgggg ggatgaatag 3300 cggtgataag ggagaatagg aatgggggtt taaggaggga gaaggaaaag aatggag 3357 <210> 177 <211> 3357 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 177 ttttattttt tttttttttt ttttttgagt ttttattttt attttttttt attatcgtta 60 tttatttttt taatttggtt tttttgtagg tgttagttga cgaggtatgc gggtgttttt 120 ttgtacgtga tgtttttgag tttacgggtg atttttgtcg tttgtttaag cgttagtgta 180 atcgttatta ttgttgggag aagttgcggc gtgcggaagt ggatttggag cgcgtgcgtg 240 tggtaggttt ttgtgcggtt ttggtgttgt atgtggtagg tttttatgtc ggacgtggtc 300 ggggtaggcg gggttgtagg tgtttttgtt taggattttt gtcgtttttt tggtagtggt 360 ataagttgga cgagttgttt gagtaggagc gtaatgtgcg tatagttatg ataaatcgcg 420 cgggattgtt ggttttgatg ttgtattaga cgatttagta cgattttttt attatcgatt 480 tgcgttttag tgtcgatcgt tgagtttttt ggttcggatt ttttatattt tgtattttag 540 atgggggagt cgttcggtgt tcgtgtgttc gtttttttat ttatttgttt tttcggtttt 600 ttttgtgttt atttatcggt tgatcgttta tttgttttta ttagagggat tgttttcgtc 660 gatatgttta gtgtttggtg gggttgcgga gtttatttat ttttgttttt tttttttggg 720 ttttgttaat aaaattttga agaaattaag gaagttgttt ttatattgtt gcggttgtaa 780 ttgttttaga tttttggata agatgggggg cgtttgtatt tcgcgagagt ttagggattt 840 atatttttag ttttttacgg gtagagggtt tacgtagcgc gtttttagtg tggtgatatc 900 gtttatgtat gtttttgttt tttatttaga gttgtcgttc gttgtggacg ttaggtttcg 960 tttttttttt ataagtttta cgttggggat tcgttttttg taggggcgcg ttttttcgcg 1020 tgttttagtt tatttgcggt gtggtatcgt tttttttttc gtttcgcgcg tttttatagt 1080 tgttcggcgg ggaggaggga gcgggatacg attttttttg gggttgatgt tcggagggat 1140 ttacgaatat aggatagatt ttagcgagag gtgggagagg agagcgtcgg tagggttagg 1200 gagtgcgtag gcgcgaagta gtttttttgt cgcgttcggt atcggttgtg gagatcgcgg 1260 gagggaaggg agggcgtagg cgtaagtttt tttcgatcgt ttttttttag gttgaggttg 1320 gaaagcgtat gcgttagtta gatgggtagc gaggagagtc gtaattgtta gtttttcgaa 1380 ggggttagtt gtcgttgaac gttagtacgt agatgtaatt ggttttcggt aggggggcgc 1440 gcgtatcgtt gcggagcgtc ggttcgtagg cgcgggagtt tttttattaa gggtacgcga 1500 tatcgaggta atagtgcgta ggtgtttagt tagaggcgga gttcgagagg taggtagcgg 1560 attttcggtt tcgggagtaa cgaatagtcg cggaggcgat agttatcgtt ttagaggagg 1620 cggtcgcgga ggaggaggaa ggggaggagg gcgaggcggg aggtgtagga gggattttcg 1680 ttatgggttt acgggtttag agtggcggaa gatatcggtt tggtgttaaa ttggtgagat 1740 agttttgggg ttggacgtgg agagcgttta ggcggaggat gggaaggaat tgtggtttag 1800 aacgttgacg gggaggaatg aagggttttt aggtcgataa gggggaggaa tggcggcgtc 1860 ggaatattga cgaggagaaa tggggggatt taggttgagg acgggaagga atgtagtttt 1920 gaattttgat aggtaggagt gtcgggattt tgggacgagg acggagagga atggtggaga 1980 ttagaacgtt aaagggagat atcggggtat ttgaagttga gagagaaatg ggggtttaga 2040 attttgagag ggagaaatga ggggttttta ggttgatgat aggagaaata gaggttttgg 2100 aatgttgaaa gggaggaata ggaggtttta tatagaggac gaggagtagt aggggattag 2160 aatggtgata gttagggatg gtatgatttc gggataagaa tagagagaat ggaggagggt 2220 tcggaatgtt gaggggagaa attagggttt ttttggatga taagggagga atggaggatg 2280 agaatagtaa ggaggagaag tggggaattt tttggttgta gaggaaggtt tgggagttta 2340 gattagggag aaattgtggg tgagaatatt gaaggagaag aaaaataagg ggggaggttt 2400 tgggttgagg aaggggaggt atgggaggtt tttagtgtga ggaatggaaa agatgagggg 2460 ttgtttaggt tatgggttgg agtagttgtg tttcgtagag gaagtcgagg ttgtaatatt 2520 gaggtagtag gataagagga tattaggtag agaaggaatg gagtggttaa aatattgaag 2580 gagggaaatt aggaattttt gggttaagga aggggggaat gagagattat tgaagttaag 2640 tagtgagggt aagagaaatg gggttttttg gggttgagga tggggattat gggggttttg 2700 gggtgataaa atagagggat agaggttttt aggttagtga tagggaggaa tgagggggaa 2760 ggatgaaaag tttttggatt ggtagtgagg agaaatgatg ggttgttagt ttgaggatag 2820 agaggagtag gggattagga tattgagaat aagaaatagg gatttttggg ttgaggaatg 2880 atgatatttt aggtttagaa taggaaagaa tggggtgaga atatgagggg tttttttttt 2940 atatatgggt tggttgtttg tggtaggttt tagggtttgg gtaagtatta atggatatta 3000 gtgatttgtg tggtttgggg tatagtgttg ttttttttta gagttttagt tttttttatt 3060 ttttttattt ttttttaggt tattgttgtt ttttgtggtt tttatggttg aggattggtt 3120 ggattgttcg gttttgggtt ttggttggaa gcgtcgcgaa gtttttcgta agttaggggt 3180 tatttgtgga cgtttagata tttattatta gaggtattgg gtgggtagtg ggtagagtta 3240 ggagtggggt agagtttgat tttggtaaaa ttaaatggtg tggttaaatt tatggatgaa 3300 gtttaaatta tgtatatata gttaattttt attagcggat tttatgtttg aatttta 3357 <210> 178 <211> 2170 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 178 gtgatttttt tttttaggat ttagtagtat tttatcgcgt tatagtagtt agtattttta 60 aagtatatat tttaatattt ttcggtcgta gtatatttaa ttttttcgtc ggggcgtggg 120 ggtttttttt ttttcgagta tagttttcgg tttttcgatt ttttttgttt tattttttcg 180 ttttttaagt atattgtgtt tattttttta ggtagttttt ttagcggtcg ggtagtagta 240 gggtttcgag ttcgtttttt tcggggcggt tatacgtgtt tattttttgg ggttggggat 300 cgtttttttc gtttggttgt tgattggtgt ttttttttat tttatttttt tcgtcgtttt 360 ttagttttta ttttatttcg ttttagttta attagtttta tcgttttttt ttttcggaga 420 aaaaagttat tttagagttt tttgggcgtc gttttcggtt ggaataaaag cgttaagaaa 480 taggtggaaa gtattttatt tttttaggtt ttatattttt agggtggata gttcgttttt 540 gtttcggttt tgttttcggt attaataata attgaatttt tatacgtgta cgtttttgtt 600 tttagttcga tcgaaaggat tatttcgcgg gttttttaaa aggacgcgat tatttaggtt 660 aagtgggggt gggagagttt ttggtcgttt ttttttggga aagtgtttta attttttagt 720 tttaaagttt tggagggcgg agggcgtttc gtgagagttt tcgggggtgc ggttcgcgtt 780 ttttgggttt tgcggatttg ggttcggggg cgcgcgtttc gttttttttt ttttttggcg 840 gtgtagttgt tcgggcgggg gtggggcggg ggtcggggtt cgcgtgggat taattaggat 900 cggggcggga gtcgatcgcg gtcggcgggg agggttagtt tcgttttggc gggcgggcgc 960 gtggtagggg ttttcggagg tttcgagttt tcgggaggcg tttcggttaa tttcgggtcg 1020 gtggggatcg ggtttgggcg cggggttttg aaggtgtgga aggaaagttt gggatttcgt 1080 tattttttta tagcgttttt tttttcgtaa tatttagttt ttttatcgcg gggttcggga 1140 gtttttggag ttgatttcgt tattattatt ttttcgggcg agcgcggagg acgggttggt 1200 tattttggtt aggtcggagg tgttttttag ttcggggttt tgtgataatt gggtcgaaat 1260 tcgagggttt tggagcgcgg cgggtggcgg gagtttgcgg agcgcggcgt attcggcggt 1320 taggtatcgg ttagtttagc ggtagttttt ttttttttat ttttattttt atttttggaa 1380 ggagttgaga attagtcgat tggttggtag gttgaattgt tttttttttt atggtaatat 1440 gtgtcgtgat tttttatttt ttgtttttgg ataaaggtga atggtaattg cgttggttag 1500 tttttgtttt ttgttttgcg gatgggttcg tcgacgtagt aattaaaatt agagttattt 1560 ttttggaaga gtaaatcgtt gttgttgttt ttttagtttt acggatttta ttttgtgtta 1620 ttttcgggtt gattttaatt cgtttatttt agagtttttt gttttatttt tatttttaga 1680 tttagtcgtg tttgttgaaa tattagttgt tttttttgtg aatgaagtgt gggaatttgt 1740 tttcgtcgta gttaatgaaa ttaggaaaat aaaaagatta aaagggttgg ggatgggaga 1800 atgaagagga atgtagatag atagtttagg gttatttatt ggtttttggc gatttttagt 1860 tttttaagtt gattaaaata atgtgaggaa atgtgggttt ttttattttt taggaagagg 1920 taataacggg tattttacgt ggcgttatag cgtttgtttt taaagtttga acgtgaatgt 1980 agtaagtata attttattaa tgaaaatatt ttttagataa ttgttaatat tgacgaaaga 2040 agagaaatag agatacggaa gttaaagagt tgggaatttt aaaggttaaa ggatgttttt 2100 tagttatttt gatgttttgt gttttttttt agttggtata aaatcgtgag tagtttaatt 2160 atattttgta 2170 <210> 179 <211> 2170 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 179 tgtaggatat aattaaatta tttacgattt tgtattaatt gaaagaaaat ataggatatt 60 agagtaattg agaaatattt tttgattttt aggattttta attttttagt tttcgtgttt 120 ttgttttttt tttttcgtta atattaatag ttgtttaaag aatattttta ttaataaaat 180 tatgtttgtt atatttacgt ttaaattttg aaaataaacg ttgtggcgtt acgtaaaatg 240 ttcgttatta ttttttttta aaaagtggag aagtttatat ttttttatat tgttttaatt 300 agtttaagga attaagaatc gttaaaagtt agtgagtggt tttagattat ttgtttatat 360 ttttttttat ttttttattt ttaatttttt tgattttttt atttttttga ttttattaat 420 tgcgacgaga gtaagttttt atattttatt tatagaagaa gtaattgata ttttagtaaa 480 tacgattaaa tttaaaaata aaggtgaggt aaagagtttt gaaataaacg agttaaaatt 540 aattcgaaaa tggtataaag taagattcgt ggggttgggg aggtaataat aacgatttgt 600 ttttttaaaa gagtggtttt aattttgatt attgcgtcgg cgaatttatt cgtagaatag 660 aaaataaaaa ttgattaacg tagttgttat ttatttttgt ttaaaggtaa aaggtgaaaa 720 gttacgatat atattgttat agaagagaag gtaatttaat ttgttaatta atcgattaat 780 ttttagtttt ttttaaaaat aaaaataaaa ataggagaaa gggggttgtc gttgggttgg 840 tcgatgtttg gtcgtcgagt gcgtcgcgtt tcgtaagttt tcgttattcg tcgcgtttta 900 ggattttcgg gtttcggttt agttattata aagtttcggg ttggaaaata ttttcggttt 960 ggttagaatg gttagttcgt ttttcgcgtt cgttcggggg gataatggtg gcgagattaa 1020 ttttaagggt tttcgagttt cgcgataaag aggttggata ttacgggagg aaggacgttg 1080 tggaagaata acggagtttt aaattttttt tttatatttt tagagtttcg cgtttaggtt 1140 cggtttttat cggttcgaag ttggtcggag cgtttttcgg gagttcgggg ttttcgggag 1200 tttttgttac gcgttcgttc gttagagcgg ggttagtttt tttcgtcggt cgcggtcgat 1260 tttcgtttcg gttttagtta attttacgcg ggtttcggtt ttcgttttat tttcgttcgg 1320 atagttgtat cgttagggag ggggaggggc ggggcgcgcg ttttcgggtt tagattcgta 1380 ggatttaggg ggcgcgggtc gtattttcga gaatttttac gaggcgtttt tcgtttttta 1440 ggattttggg attggggagt tgaagtattt ttttaaggga ggacggttag gagttttttt 1500 atttttattt ggtttgagtg gtcgcgtttt tttaaagggt tcgcggggtg gttttttcgg 1560 tcgggttaga gatagaaacg tgtacgtgtg ggagtttagt tattattgat gtcgagggta 1620 gagtcggagt aggagcgggt tgtttatttt agaaatatga agtttagaga agtgaagtgt 1680 tttttatttg ttttttaacg tttttatttt agtcgagaac ggcgtttaag gagttttgaa 1740 gtggtttttt ttttcgaggg aagaaggcgg tggggttgat tgagttggaa cgaagtagga 1800 tggaggttgg agagcggcgg gaagggtggg gtagggggag gtattaatta gtagttaagc 1860 gggaagagcg atttttaatt ttagggaatg gatacgtgtg atcgtttcgg agaagacggg 1920 ttcggaattt tgttattgtt cggtcgttga aagagttgtt tggaagagtg agtataatgt 1980 gtttggaagg cggggggatg gggtagagga aatcgggaag tcggggattg tgttcggagg 2040 ggaggagatt tttacgtttc ggcggaggga ttgaatgtgt tacggtcgaa gggtgttgga 2100 gtgtgtgttt tagaaatgtt aattgttgta gcgcggtgga gtattgttaa attttaagaa 2160 aaaaaattat 2170 <210> 180 <211> 2251 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 180 ggatttcgag tcgtttttag gtagttagga gcggttttag cggtagtcgt aaattttagt 60 agtcgttcgt gttgttcgtg gttggggcgg agggtagtta gagttgggga ttaaggtttc 120 gcgttatttg cgcgtatagt tttatatttg aacgttgttt tttcgtagac gagatcggcg 180 ggtattgtaa agttgggatt cgtttttgaa ggaaaaaaaa tagcgagtaa gaaatttagt 240 attatttttt attgatttat ttcgttgtat tttttgtttt ttaagttttt gaaagttggt 300 aattttgatt tcggtgttta aaaatcgata gttattgaga tcggttttga gaagtcgaag 360 atttggtagt ttttagattg agtaggataa ggtgaaagta ggttggaggc gggtttagga 420 tatttgaggg ttgattttgg gggttcgtga ggttgttatc gttgttgtcg ttataggtga 480 gatggcgttg ggttgacgtt ggggttaacg ggtagagaac gtagggatgc ggttttcgtc 540 gaagagagtt aagaagggaa gagcgcgttt tttaaattgt ttttgtaatt tgtttttagt 600 gagtatttta ttgatttaga atttatcgag aatagtatta gcgagttatt ttttttttga 660 gatgggtttt atttattttg gtaatggagt gagttggatt gtggggagga agaggaatgg 720 gaaaattagt ttataaatat taatgttagt aagagtgtgt tgttggtagg acgtatcgcg 780 agtttggaga ttttggtggt cgtagttggt aagtggttat aatttagaaa gtaggatcga 840 gttgtttttt ttgttttatt agtgtatcgt ttttcgggcg cgggtttaat attttataag 900 tggtaatttt cgtttacggt agttttgttt tttttttatt atttttagat ttagttttgt 960 attttaaggt tgcgtatcgt tagttattat tatgtttatt ttcggggtta attcgttcgt 1020 ttttttgagt ttcgatcggt tgaatagttt agtgattatt tcggcggtga tgtttatttt 1080 cggggtggtg ggtaatttgg tggttatcgt ggtgttgtgt aagtcgcgta aggagtagaa 1140 ggagacgatt ttttatacgt tggtatgtgg gttggttgtt atcgatttgt tgggtatttt 1200 gttggtgagt tcggtgatta tcgttacgta tatgaagggt taatggttcg ggggttagtc 1260 gttgtgcgag tatagtattt ttattttgtt tttttttagt ttgttcggtt ttagtattat 1320 ttgcgttatg agtgtcgagc gttatttggt tattaattat gtttattttt atagttatta 1380 cgtggataag cgattggcgg gttttacgtt ttttgtagtt tatgcgttta acgtgttttt 1440 ttgcgcgttg tttaatatgg gtttcggtag ttcgcggttg tagtatttag atatttggtg 1500 ttttatcgat tggattatta acgtgacggc gtacgtcgtt tatttttata tgtacgcggg 1560 ttttagtttt ttttttattt tcgttatcgt tttttgtaac gtgtttgtgt gcggcgcgtt 1620 gtttcgtatg tatcgttagt ttatgcgtcg tatttcgttg ggtatcgagt agtattacgc 1680 ggtcgcggtc gtttcggttg tttttcgggg ttatttcgtt gtttttttag ttttgtcgcg 1740 ttttagcgat tttcggcgtc gtcggagttt tcgtcgtatc gcgggcgtcg agatttagat 1800 ggttatttta tttattgtta tttttttggt ggtgtttatt tgttttattt cgttcgtggt 1860 gagtgatcgg ggttggggtt ttattcggtt tttttttcgt atttattttt cgcgtttatt 1920 tttcgttttt tgtttttttt ttgagttttt ggtagtgaac gtgtcgtttt taggtcgggg 1980 ttgggatttt tatattgttt tttagagtag gtttaatttt ttttgaagtt ttaattttaa 2040 cgagatttag taggtgtttt gtttttatat tttttagttt atgttttcgg aagtttgggt 2100 tttttttttt atcgagatag tttttatttt ttgttgtttg atattggtcg agttttttaa 2160 gaaaattttt cgtttttttt gttagacgtg gaggggagtt tgttgtagtg tgatttagtt 2220 tattttttcg tattgtgaat tgtgaattgt a 2251 <210> 181 <211> 2251 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 181 tgtagtttat agtttatagt acggaggaat gggttaagtt atattatagt aggttttttt 60 ttacgtttaa tagagggggc ggggggtttt tttggaagat tcggttagtg ttaggtagta 120 aggggtaagg gttgtttcgg tggagaaaga aatttaggtt ttcgggaata taaattgggg 180 gatgtagggg taaagtattt gttaaatttc gttagggttg ggattttaaa gagggttggg 240 tttgttttga gaaatagtgt gggaatttta gtttcgattt aaaggcgata cgtttattgt 300 taaggattta gagggaaagt agggagcggg gaatggacgc gggaggtgga tgcgagaaaa 360 aggtcgagta gggttttagt ttcggttatt tattacgagc gggatggagt agatgagtat 420 tattagggag gtggtaatga gtaagatgat tatttggatt tcggcgttcg cgatgcggcg 480 gaagtttcgg cggcgtcgaa agtcgttgag gcgcggtaag gttggggagg tagcggggtg 540 gtttcgggag gtaatcgagg cggtcgcggt cgcgtggtgt tgttcggtgt ttagcgaggt 600 gcggcgtatg aattggcggt gtatgcggag tagcgcgtcg tatataagta cgttgtagag 660 gacggtggcg agaatgagga aggagttgaa gttcgcgtat atgtaggagt aggcggcgtg 720 cgtcgttacg ttggtggttt agtcgatgaa gtattaggtg tttgggtatt gtagtcgcga 780 gttatcgaga tttatgttgg gtagcgcgta aaagagtacg ttggacgtat agattgtaaa 840 gagcgtgagg ttcgttaatc gtttgtttac gtagtggttg tagaaatagg tatggttgat 900 ggttaggtag cgttcgatat ttatggcgta gatgatgttg aggtcggata ggttgaagaa 960 gagtagaatg aaggtgttgt attcgtatag cggttggttt tcgggttatt ggttttttat 1020 gtacgtggcg atggttatcg ggtttattaa taaagtgttt aataggtcgg tgatagttag 1080 tttatatatt agcgtgtaga aggtcgtttt tttttgtttt ttgcgcgatt tgtatagtat 1140 tacgatggtt attaggttgt ttattatttc gaagatgaat attatcgtcg ggatggttat 1200 tgggttgttt agtcggtcgg ggtttaagga ggcggacgaa ttgatttcgg gagtggatat 1260 gatagtggtt ggcggtgcgt agttttggag tgtaaggttg ggtttgggga tggtagaaga 1320 gagataaagt tgtcgtgagc ggaaattatt atttgtaagg tgttagattc gcgttcgaga 1380 aacgatatat tgataagata aggggagtaa ttcgatttta ttttttggat tgtagttatt 1440 tattaattgc ggttattaaa atttttaggt tcgcgatacg ttttgttaat agtatatttt 1500 tgttgatatt aatatttata aattgatttt tttatttttt ttttttttta taatttaatt 1560 tattttattg ttaagatgaa taagatttat tttaagggaa aagtagttcg ttagtgttat 1620 tttcgataga ttttgaatta ataaaatgtt tattgaaaat aagttataaa agtaatttgg 1680 agagcgcgtt tttttttttt tggttttttt cggcgagggt cgtatttttg cgttttttat 1740 tcgttgattt taacgttagt ttaacgttat tttatttgta gcggtagtag cggtggtagt 1800 tttacgagtt tttagggtta gtttttagat gttttggatt cgtttttaat ttgtttttat 1860 tttgttttgt ttagtttgga aattgttaaa ttttcggttt tttaaagtcg gttttagtgg 1920 ttgtcgattt ttggatatcg aggttagagt tgttagtttt taaaaatttg ggaaataaga 1980 ggtgtagcgg gatgggttag tgaagaatgg tgttggattt tttattcgtt attttttttt 2040 ttttaaagac gagttttagt tttgtagtgt tcgtcggttt cgtttgcggg aggatagcgt 2100 ttaggtgtga ggttgtgcgc gtaggtggcg cggagttttg gtttttagtt ttggttgttt 2160 ttcgttttag ttacgggtag tacgggcggt tattggagtt tgcggttgtc gttgaggtcg 2220 tttttggtta tttgggggcg gttcggggtt t 2251 <210> 182 <211> 2297 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 182 agaaaaatat tatcgtgttt tttcgtttgt atttaatata tttaaggttt tttatttatt 60 tttttggaat aaatttttag taaatattta tttatcgatt tgggagcgat ggatttttat 120 aaaggtttga tcgtttttta agtggtcgaa gtgatttgtt ttcgtggttt ttttagtatt 180 gaagggggtg ggggaagcgg atttgagggg gtgtatgttt ttgtcgtcgg tgggtttatt 240 ttttaaaaat tattgagatg cgttagggtg gtcgtgatta agcgggttta gggttaattg 300 tgtgaggggg aagcgttttt tagagcgcgc gtagcgtcgg gggtttagtt tacgtcgttg 360 cgcgtttttg tgcgtatcgg gtgaggatgt cgagttttgc gggtatttcg gaagtcgcgg 420 tggaggtagg ggtttcgttc ggcgtagtgg gtttgttggg gaggtgtagg ggaggttttg 480 atttttggtt tatttttttt tagatttttt cgttcgtttt cggattttta gggttttttt 540 ttaaattttt ttttgttttt tttacgggag gtttttgtag tttttgggtt ttagggtttc 600 gtaagtttcg ggatcgattt gtgttcgggg tgggtgtggc ggaagtttga atcggattat 660 ttaggtacgt tatttgtaga cgtagtgggc gagggggatt ttgttatttt tttagttttt 720 tttttggatt tcgtagcgag gggaattaaa ttttttttat gatagttttt ttggcgttag 780 tttggatcga gtggttatag gttggattag ggtaggtaga agatgtattt ggtattttat 840 cgaacggtat ttgaattcgt ttttattatt tattaatggc gtgattttag gtaatttatt 900 taaatttttc gaattttagc ggtttttatt tataatatgg gggttaatga taatgttttt 960 ttcgtatgta ggtggattaa atggatataa agcgtttatt ttcgttcggt acgtttaaaa 1020 tttttattaa taggttagtt aattttatta cgagaggaat tttttttttt tcgtttttta 1080 gagtgtgggc ggtatgaggt tacggaagta gttgttgtaa ttagtatttt aaaatttaga 1140 gattttttaa tggtggtagg gggtgaaagg gtagggggga ggtagggttg ggataggtag 1200 aggtaggttt ttggggattt ttagttttgg ggattaagcg tttggaatta gttgggtttg 1260 ggtagaaata agaaggtaaa tgacgggatc gtcgtcggag ttcggatttt tatttttgga 1320 gtttattgtt ttttttaggg aatagaggag tgttttggtt ttttagtaat gaattaggag 1380 agtgtgagaa agagtatttg tttttttttt cgtggttcga taagttattt ttcggtagtt 1440 ttgcgagtag attaattgaa acgggtttgg aattttattt ttttttttcg atggagttgt 1500 tggaggtttg cggatattgt ttggttagtt ttcgggatta tagcgtcgtg ggtttttttt 1560 cgtggtgttt gttttaaatt tgggtgttat taatttattt aataatgacg gatgattttg 1620 ttataacgac gttagttaaa atattttcgg tttaattttt ttttaattaa tatcgaagta 1680 ttttgaatga gattcggatg aagtttgaat agtacgtttt ttaggtttag aaaatttgag 1740 tggtgggaag agaaaaagaa ataagtagaa attaggaaag aatggttatt aattgtttag 1800 attggtaagt gttaaataag ttaggttgtt tggaaaaaga taaatgtcgt tttttttttt 1860 tacggtatgg ttagaatttc ggcgatggga aagtattttt tgagtcggtt aattttatat 1920 attttgtttg tgttttttat tatttattat cgaaaatgtt aggaagagtt ggggggtaag 1980 tgtttttttc gtgggtgcga gattgtatcg aagggttgtt ttggtataaa gtttggggag 2040 aggatatggt ggaggtgggg ttgtattttt attttgtttt tttaatatta ggttttgggt 2100 agagaaattt atgcgtgatt ttttgcggta gtcgtaggta gttgatcgta aatagtttcg 2160 ttcgtgtttc ggagtagttg tgttattaga cgtaatattg gatatttgtt ttcgggtttt 2220 aagaaggaga gggaaagagt tttttagaag ataattcgag aaggggttag tagagcgttg 2280 ggtggagtgt agatttt 2297 <210> 183 <211> 2297 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 183 ggagtttgta ttttatttag cgttttgttg attttttttc gggttgtttt ttggagggtt 60 tttttttttt tttttttggg gttcggagat aagtatttag tgttacgttt ggtggtataa 120 ttgtttcggg atacgggcga ggttgtttgc ggttagttgt ttgcggttgt cgtaggaggt 180 tacgtatagg tttttttatt taaaatttgg tgttagaggg gtagggtggg agtgtagttt 240 tatttttatt atgttttttt tttagatttt gtgttagggt agtttttcga tgtagtttcg 300 tatttacgaa ggaggtattt gttttttagt tttttttggt attttcggta gtagatggta 360 gagggtatag gtagggtgtg tgaaattgat cgatttagga ggtatttttt tatcgtcggg 420 gttttggtta tatcgtaaag agaagaaacg gtatttattt ttttttaaat aatttaattt 480 atttagtatt tgttaatttg agtaattaat agttattttt ttttgatttt tgtttgtttt 540 tttttttttt tttattattt aagttttttg aatttgggaa acgtgttgtt tagattttat 600 tcgggtttta tttaggatgt ttcgatgttg gttggaagag agttagatcg aaaatgtttt 660 gattggcgtc gttatgataa ggttattcgt tattgttgga tagattgata gtatttaagt 720 ttaaggtaga tattacgagg gaaagtttac ggcgttgtgg tttcggaggt taattaggta 780 gtgttcgtag atttttagta attttatcgg gaggagagga tgaagtttta ggttcgtttt 840 aattaatttg ttcgtagaat tgtcgaagag tggtttgtcg ggttacggga gaagaaataa 900 atgttttttt ttatattttt ttggtttatt gttgagaaat taggatattt ttttgttttt 960 tgggagagat agtgaatttt agggatggaa gttcggattt cggcggcggt ttcgttattt 1020 gtttttttgt ttttgtttaa atttagttag ttttaagcgt ttggttttta agattggaag 1080 tttttaagaa tttattttta tttgttttaa ttttgttttt tttttatttt tttatttttt 1140 gttattatta gaaagttttt ggattttgaa atgttagttg tagtagttgt tttcgtggtt 1200 ttatgtcgtt tatattttgg gaagcggagg agggagggtt tttttcgtaa taagattagt 1260 tgatttgtta atgagagttt tggacgtgtc gggcgggggt aggcgtttta tgtttattta 1320 atttatttat atgcggagaa ggtattatta ttaattttta tattgtagat ggggatcgtt 1380 gaggttcgga aagtttagat gggttgttta aggttacgtt attaatgagt aatggagacg 1440 gatttaaata tcgttcggta aggtgttaag tgtatttttt gtttatttta gtttaatttg 1500 tagttattcg gtttagattg acgttagagg ggttattatg ggagagattt ggtttttttc 1560 gttgcggggt ttagggaaga agttgagaag gtagtaaagt ttttttcgtt tattacgttt 1620 ataggtggcg tatttgggta attcgattta agttttcgtt atatttattt cgggtataag 1680 tcgatttcga ggtttacggg attttaaggt ttagaggtta taggaatttt tcgtgaaggg 1740 ggtaggagaa agtttgaggg agagttttga aggttcggga gcgaacgaaa aagtttggaa 1800 gggaatagat taggagttag gatttttttt gtattttttt agtaggttta ttgcgtcgag 1860 cggggttttt gtttttatcg cggttttcgg gatgttcgta gagttcggta tttttattcg 1920 gtgcgtataa gggcgcgtag cggcgtaagt tggattttcg acgttgcgcg cgttttgagg 1980 ggcgtttttt ttttatatag ttgattttgg gttcgtttgg ttacggttat tttggcgtat 2040 tttaatagtt tttagaaagt gagtttatcg acggtaagga tatgtatttt tttaaattcg 2100 ttttttttat tttttttaat attgagaaga ttacggaaat aaattatttc gattatttag 2160 aaagcgatta aatttttata aaaatttatc gtttttaaat cgatgggtga atatttgttg 2220 ggaatttgtt ttagaggaat aaatgaggag ttttgagtgt attaaatgta aacgggggga 2280 tacggtggtg ttttttt 2297 <210> 184 <211> 2590 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 184 gcgttgagta ggcgcggtta cggtgtttag atttttcggg ggtattttag ttttcgttat 60 ttagtggttt acggttgcgg gttttagggt ttgaggttgg ggattatcgt tgtcgtcgta 120 gtttttatat ttcgaagttg ttttgttgtt tgtgttgttt tcgtagatag tatttttggc 180 gttttgtgcg tttttttttt tttttttttt tttttattcg tttttattgt tttgagtttt 240 tgaaagttgg gagaatcgga gatatttttg aggattggta atgaagtttt atttaagtgg 300 gatgtaattt tcgttttttt attttttttt aagaaggagg ttgtgttttt attttgtttt 360 gttttgggtg ttgattttta aaaaattaga gtaaaatgaa cgtgaataaa aagaaaagga 420 gaaatgtttc gagttggggt agagggagta gagaaggagt ttttatcgcg gtcggaatgt 480 agagcggatt ttggtttagg attgggtttt tttttaggtt cgggtttatt ttggttttcg 540 ttgttggaat ttttaggagg taaagcgatt tcgatttttg ttgttcgtat tttcgggcgt 600 gagtgttttt tttaggaggt ttaggaggtc gtttttgttg tattttgagt tttcgttgta 660 aaaattgaag ttcgtgggtt tcggtaggtt ttttagttcg ttcgtttcgg gataggtttt 720 cgtttatatt tttggaagta aggagtttcg ggttttttcg tttttttcgg ggtgtggagt 780 ttttggggtt tttgaaaggt gaggttttag aggcgaggga ggggtgagcg gggagttttg 840 ttcgtttgcg gttgcgtttt cgttgtggat taggaggtag gttaattttt cggattttgg 900 gggaaaaatt atagcgggtt ttttgcggaa attttggtcg ttttaatttg ttaagagttt 960 gagtgaggtt ttggaagttt ttagtttcgg tttaggtcgg gacgcggttg ttgagttttt 1020 ttaggttcgt aggatagcgg ttttcgtcgg tggcgtcgtt gtatttaggt tttttttaga 1080 tcggtggcgg tagttaattc gagatttgcg tttttcgggt tcggggtagt taggaggtcg 1140 gcgcgtagcg ggtcgggtta ggattgggtc gagtagatag agttgtagtt ttcgttttgt 1200 tcggtttttc gcggttggag agtagagcga tgttattcgg agtttcgttt gggtggtaac 1260 gagattttgg ttagttattt ttgtagttta gattaatttt ttttaatagt ttttgatggt 1320 aattatagta atcgaagttg ttatatattt ttaggtaatt atgatatata aaaagtttcg 1380 aggggatttt ttggcgaggg aagttaagaa cggtttttta gttttaggaa atttcggttc 1440 gttttacgtc ggagttcgtt cggtttgtta aatgagagga gttttgtaac ggggttaatt 1500 agtttgtttc gtgattttaa gttattttaa cgtggttggg tggcggagtt tgaggtatag 1560 gttcgttatg tttcggaatt ttcgcgtttt ttttttttgg gtttcgtttt agttcggttg 1620 tttgttttta atttgtttcg ggagtcgcgg tttagaggtt tgtttagagg taggattcgt 1680 attggtggtg gtttagaggg taatagttcg gaagttcggg cgggggaatt cgaggagggg 1740 tttttatttt gtattggttt tttttttatt tttatcgggt tttttagaga tgttgttatg 1800 ggttttttgt tcggatggga agtggggaaa aagagatttt attattgttt tttttattta 1860 tttattttgg tatttttaat agtgttatag ggaagaggat agttggggtg atagtattgt 1920 tgggttttaa acgtggattt tggagcggtt agagggcgcg tgttaagtag aggatggttg 1980 taagatatgg aaattaagtt tatcgttttt agagtgagtg tagtgtagcg gagttttaga 2040 ttcggttttt gagcgattag gaattttttt gggcgtagtg ataggttcga aggagtggag 2100 gataagattc gttgtgtttt tgtttggttt tttttagttt ttttttttta tagtataatt 2160 ttttttttcg ttttgtggga ggggggcgtc gagtcggtgg tcgtcgcgtc gcgcgttttt 2220 tttgttcgtt tttgtcgtcg ttcgaatttt tatgttattt tttttgacgg gttattggtg 2280 gttttatagg taggtgttgt cgcggggttg taattattcg gtcgagtttg gtcgttatcg 2340 aatatttttt tatttttaag tacggttttt cgcgtttttt tttttttatt ttttttattt 2400 gagacgagtt tgggatttac ggtgtaagtt cgttcggacg tttcgggttt taggagtaag 2460 tttatatttg cggtgtttcg aggttttttt cgcgttacgt ttttattttt tttatttttt 2520 tcgtttagac gttttattgt cgtttttttt tattttaatt ttatcgtagt ttttaattta 2580 agcgttttcg 2590 <210> 185 <211> 2590 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 185 cgaaagcgtt tgggttgggg attacgatgg gattgaggtg ggaaggggcg gtagtggaac 60 gtttgggcga ggggagtagg ggaggtgagg gcgtggcgcg gggagggttt cgaggtatcg 120 taggtgtaaa tttgtttttg gaattcgagg cgttcgggcg agtttgtatc gtgggtttta 180 gattcgtttt aggtggaggg ggtgggggaa ggagagcgcg ggggatcgtg tttgggggtg 240 agggggtgtt cggtaacgat taggttcggt cgggtaatta taatttcgcg gtagtatttg 300 tttatagagt tattagtgat tcgttaaaaa gagtagtatg ggaattcgga cggcgataaa 360 ggcgggtagg ggaggcgcgc ggcgcggcgg ttatcggttc ggcgtttttt ttttataggg 420 cgggagggga gattgtgttg tgggagggag gggttggaga gggttaggta agggtatagc 480 gggttttgtt ttttattttt tcgggtttgt tattgcgttt aagggagttt ttggtcgttt 540 aggaatcggg tttggagttt cgttgtattg tatttatttt ggaagcggta aatttggttt 600 ttatatttta taattatttt ttgtttaata cgcgtttttt gatcgtttta gggtttacgt 660 ttggggttta gtagtattgt tattttagtt gttttttttt ttgtggtatt gttgaagatg 720 ttaagatgag tgagtgggag gagtagtggt ggggtttttt tttttttatt ttttattcgg 780 ataggaggtt tatgataata tttttggaga attcgatgag ggtggaggga agattagtgt 840 agggtggggg ttttttttcg gattttttcg ttcgagtttt cggattgttg ttttttaggt 900 tattattagt gcgagttttg tttttgagta gatttttgag tcgcggtttt cggggtagat 960 tagaaatagg taatcgggtt ggggcggggt ttaggaggga gggacgcgaa aatttcgggg 1020 tatagcgggt ttgtgtttta gatttcgtta tttagttacg ttaaggtgat ttggggttac 1080 gagataagtt ggttgatttc gttgtaaagt tttttttatt tagtaagtcg agcgagtttc 1140 gacgtgaggc gagtcggagt tttttgaagt tggaaaatcg tttttaattt ttttcgttag 1200 ggggtttttt cggggttttt tgtgtgttat aattgtttaa agatatatgg tagtttcgat 1260 tattgtaatt attattagag gttgttgaaa gaagttagtt tgggttgtag gggtgattgg 1320 ttagggtttc gttattattt aggcggggtt tcgggtgata tcgttttgtt ttttagtcgc 1380 gagaagtcgg gtaaggcggg ggttgtagtt ttgtttgttc gatttagttt tgattcggtt 1440 cgttgcgcgt cgatttttta gttgtttcgg gttcgaggga cgtaagtttc gggttggttg 1500 tcgttatcgg tttggaaagg gtttaaatgt agcggcgtta tcggcggggg tcgttgtttt 1560 gcgggtttga gaaagtttag tagtcgcgtt tcgatttgag tcggggttgg aggtttttaa 1620 ggttttattt aggtttttgg taagttagaa cggttaaagt tttcgtaagg agttcgttgt 1680 ggtttttttt ttaaagttcg gagggttggt ttgtttttta gtttatagcg ggggcgtagt 1740 cgtaggcggg tagagttttt cgtttatttt tttttcgttt ttgaggtttt attttttaag 1800 ggttttaggg gttttatatt tcgaaaagga cgaaagagtt cggggttttt tatttttagg 1860 ggtgtaggcg agggtttgtt tcggggcgag cgagttagga ggtttgtcga gatttacggg 1920 ttttagtttt tgtaacggag gtttagaatg taatagaaac ggttttttga gttttttggg 1980 aaggatattt acgttcggga atgcgggtaa taaaaatcga ggtcgtttta ttttttggag 2040 attttaatag cgagggttag ggtaggttcg agtttaaagg gaaatttagt tttgggttag 2100 ggttcgtttt gtatttcggt cgcggtgagg gttttttttt tgtttttttt gttttagttc 2160 gaaatatttt tttttttttt tttgtttacg tttattttgt tttaattttt taaaggttag 2220 tatttaaagt aaaataaaat gaaaatataa tttttttttt ggaggggggt aggagggcgg 2280 gaattgtatt ttatttaagt gagattttat tattagtttt tagaagtatt ttcgattttt 2340 ttaattttta aagatttagg ataatgaggg cgagtgaaag ggggaggggg agggaaggaa 2400 cgtatagagc gttaaaaatg ttatttgcga aaataatata agtagtaagg taatttcggg 2460 atatggggat tgcggcggta acggtagttt ttagttttag attttggagt tcgtagtcgt 2520 gggttattgg atggcgggaa ttgaaatgtt ttcgggagat ttgagtatcg tgatcgcgtt 2580 tgtttaacgt 2590 <210> 186 <211> 4133 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 186 aggattaaaa attttttttt ttaaaaagat tttagaagtt ttttttttag agaagataga 60 aaatattgat aaattgtata ttgtgtagat gtttagtttt gaaatgtagt tttgtagttt 120 tttattttgt agtttattgg ttgtatttgt atttttgggt agtgtttttg tagggtgtaa 180 atatttagag atttagggat ttggtagttt tgtgtaggtt ttttgtgtgt attgtttagt 240 gagtgggttt tttgtagatg gtgggatgtt ttaggagatt gtgaggttgg tgtagtttgg 300 tgagtttttg gagggaaggt ggtgtgttag aaaggattgg attttagtaa tggttttgga 360 ttggttttgt gtggttgttt tttttttttg ttttgttgtt gggatttttt tagttagtgt 420 tgaatttttt aattgggaag gattgagtta ttttattttt tgggaagttg tgtgtttatt 480 tgtttttggt agtgttggag tttgagttgg ggattgggtg gatatttata gagtttgtat 540 tgtagtgtgt tgtatgtttt tgtttttgtt tgttggtttg tgttttagtg aattaattgt 600 aaagttggtt tgaagtggtg atggtgtttt tgtggagttt atttgttgtt ttagtgtgtt 660 tttgagtagg gattgggttt gttggggttt ttgttgggtt tgtgtgtttg tatggtattt 720 gttgtatgag ttgtttttgt gttttttttt tgtgtttggt tgtttagttt ggtgttggtg 780 ttttatgttt tttgagtgta ggagattttt ttgttttggt tttgtttgtt ggtgttggtg 840 tttatttttt gggtgtggaa atttgagttt attttttttg gttgttggtt ttgggattgt 900 gggtttggtt atgtagtttt gtttggattt aaagagtttt agtttttgtg aatattaggt 960 ttgtgttggg agatgagaag gtgtttagtg gggtttagtg tggttttgag gggtagggtg 1020 aggtttgtga tgttgaggtt agttatggtt agttataggt gttgtgtaag gaattgggga 1080 aagttttttg ttaagaaagg gaaatgttag tttagttaaa aaaaaaaaaa aaaaaaaaag 1140 gttggggttt aatgagaaag ttttttagag gtattttttt agttttttta tagttttttg 1200 ggagtttttg aatttgtatt tgaatggtgt ggttttgggt ttgtgaaggt ttggtgggtt 1260 gaagttgttt tttaggtttt taaaggaatg tagttaggtt ggaatttatt ttttttttta 1320 atttttagaa aatggaaatg ttttttttgt gatttttttt tgttgagtta gattttaggt 1380 tttttttgtt gtgggtgttt ggtttttttt gttgatattt tggatgttta ggtttgtggg 1440 ataaaaggta gttgtggtgt tttgtgggtt ttttagtttg ggagttggtt ttaggggttt 1500 taaagtgtga ttttaggttg ataattgtaa gtttttaggt agaggggaag ttttagtgtt 1560 gagaagtttg ttttgagaat tttttgtgtt gggtgtttag tttgagtgtt ttgggtgtgg 1620 agtttatttt tggtgtgggt agggttttag ttgtaggttt ggtgtagggt ggatttggtt 1680 gaagtttgga gggttggagg tgttgggatg tagtttggat aagagggtgg atttgatttt 1740 ggaaagtttg tgggatttag gtattttaat attgggaaga taaagagatt tgattttttt 1800 gggattggtg aggggagttt ggtggggagg ggaatggtag ggtagttaag tgtgaaagag 1860 aattttttgg gtttaaagtt aatgtagtta ttttataagt tattttagag gtgattggaa 1920 aaaataataa taataaaggt gtttagtagg ttgtggttgg gaaggaaaaa taatgtttgt 1980 aagatgagtg tgttgatttg tagttttata ttttttgttt attagttgga atatatatag 2040 atttatatat ttagtaaatg taaattttat tatttaaaga tgtgtttgtt ttggttataa 2100 ttgttttaag tgtttatagg ttaattttat atatggaata ttttgaaagt gggtgatttg 2160 atttttaagt ttaattggtt tgtgttgttt gttgaattgt aaattttagt aaaatttaaa 2220 tatattggaa ttttagttgt tttttgggag tgaggaagtg ggagtaatgt taaaagggga 2280 aaagaagaat agtaaaaaaa gtataaagat attatttttt gatgtaaaat tatgggattt 2340 tttttaaatg gtataagaga atttttggag aagattatta ttaattaata agtaataatg 2400 ttttttaggg tttattagat gttttatatt tgtttgggaa ttttgatttt ttaggttttt 2460 tgagaaattt atttgtttgg aagaagttgt attttgttgt tataggagtt gttgagagtt 2520 agggatggag attttagatt taggattttg ttatgatttt attgattttt aagtgttaat 2580 agaatgaaat ggatatgttt attagttatt ataaattgaa ttattttata tgagagagag 2640 aaatgtggtt taagttttat atttgttttt taaataattg atttttttta attttgtttt 2700 taaaggtttg tggaaattag ggagggggtt ggggagatgg ttttagaaat aaaatgtttt 2760 tttttagtat ggtttttata tttagtttat ttaagttgat ttttgtaatt tatataaaga 2820 atgggtttgg gtgggtggtt agtgaagatt ggggtgagta agtgtttatg ttgttgagtg 2880 ttggggaggt ttaggtttgt ttttgtatag aattttgtaa ggagtgtgtt ttgttaggtg 2940 tttggattag agggtgttgt gtttttgtaa attttgtggt tttgatgtgt tttttttagg 3000 tattattgtt ataataagtt atatttaaaa taatgtataa atagtattgt tttttaagtt 3060 ttttttaata gtgttttata tgtattttat gaatttttaa agttatgtat atgaattttt 3120 tattgttgat ttgtataaag ttagagggat gtgtagtttt tggagttgag aatttgtagg 3180 gtgtatatgt ttttttgtat ttgtttagag ttatatattt tatgtaattt tattaatgtt 3240 taaatttaaa tgttaaaagg tatgtatgat ttgaataaag aatttattag tttagttgag 3300 tttttggttt tgggttttaa agtttttggt agttttgtga tttttttgtg gtgtagatat 3360 gtgttaagag ttgggtttga agtattaatt ttgttttttt gggattttta gtatgttttt 3420 aattagagtg ttaatgtttg tgttgttggg atttaggtgg ttgtattttt ggaggttttt 3480 gattagggta aatttaagta ttaaatgtag gtgaaaagag agtgtgtggg gttggaatga 3540 gggtttggga gtagttaagt ttgttaggat gtgtttaggt agttagttgt tgagttgagg 3600 agttgtggtt gttggttgtg gtgatttgtt gttttttttt ttattttttt ttttttggag 3660 gtggtggggg aggggaggtg atgttagtgt tttgttttgt tttttgtttt gggtgtggat 3720 gggatttttt ggttgggtgt gttattttga tagtggtagt agtggttgtg gaggttgtgg 3780 gggttttggt ttttgtggtt tttttggttg gttgtagttg tggtgtgggt gaaatgtttg 3840 tttttttttt ttggttgtgt tttttgggtg ttggtgagtg tgggtgtttt ttgtatttag 3900 tgtttggagt tgtttggagt tttgttgtgt gtattttttt ggtttgtgga gtttttttgg 3960 tggtgttttt tatgttgtgg attgtaggtg atgttttttt ttttttgtag ttgaaatttg 4020 ttgtgatgtg ttgtttgtta gatttttgtt gggtggaagt atgaatagtt tttgtagatt 4080 ggtttggatg atttgtattt tgtggttttt taatttttgg atgtgaattt ttt 4133 <210> 187 <211> 4133 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 187 aaaaaattta tatttagaag ttggagggtt ataaagtata agttgtttag gttagtttgt 60 agagattgtt tatgtttttg tttagtaaaa atttggtagg tgatatattg tgatgaattt 120 tggttgtaga agaggaagag tattatttgt agtttgtggt gtgggaaatg ttgttggagg 180 ggttttgtga gttggggaag tgtgtgtagt ggggttttag gtggttttag gtgttgagtg 240 tgaggaatgt ttgtgtttgt tggtgtttgg gagatgtagt tgaaggagga gggtgggtgt 300 tttatttgtg ttatagttgt ggttggttag agagattgta gaggttggga tttttgtagt 360 ttttatggtt gttgttgtta ttgttggggt ggtgtgttta gttggagaat tttgtttgtg 420 tttggggtgg ggggtgaggt ggggtgttga tgttattttt ttttttttat tgtttttaag 480 ggggagggag tggggaaaga ggtagtgagt tgttgtagtt ggtggttgta attttttaat 540 ttggtggttg gttgtttggg tatgttttga taaatttggt tgtttttggg tttttgtttt 600 ggttttgtgt attttttttt tgtttgtgtt tggtgtttaa gtttgttttg gttggaagtt 660 tttggagatg tggttgtttg ggttttggtg gtatggatgt tggtattttg gttagggata 720 tgttgaagat tttggggagg taaagttggt attttaaatt tggtttttaa tatatattta 780 tattgtgagg ggattatgga gttgttgagg attttagagt ttagggttga ggatttggtt 840 agattggtga gttttttgtt taaattgtgt atgttttttg gtatttaagt ttaaatgtta 900 atgaaattat gtggggtgtg tggttttaag tgagtgtggg gaagtgtgtg tgttttatgg 960 gtttttggtt ttaggagttg tgtatttttt tggttttgtg tggattggtg atgaaagatt 1020 tgtatgtata gttttgggag tttataaaat atatatagag tattgttaaa aagaatttga 1080 gaggtgatgt tgtttgtgta ttattttgaa tgtaatttat tatagtaatg gtgtttaggg 1140 agggtgtatt ggggttgtga gatttgtagg ggtgtagtgt tttttagttt gggtatttgg 1200 tgaggtgtgt tttttgtagg gttttgtgtg gaggtgaatt tggatttttt tggtgtttgg 1260 tgatgtgggt gtttgtttat tttagttttt attgattatt tatttgggtt tattttttat 1320 atgagttata aaaattagtt tgggtggatt ggatgtagag gttgtgttgg aggaaagtgt 1380 tttgtttttg gaattgtttt tttaattttt tttttaattt ttatgagttt ttggggatag 1440 ggttagggag ggttgattat ttaaaggata aatgtggaat ttgaattata tttttttttt 1500 ttatataaaa taatttgatt tgtggtagtt aataggtatg tttattttgt tttgttggtg 1560 tttaaggatt agtagaattg tggtagagtt ttaagtttga aatttttatt tttggttttt 1620 ggtggttttt gtggtgatga agtgtaattt tttttaggta gatagatttt ttagggagtt 1680 tggaaaattg ggatttttag atagatgtaa aatatttagt aagttttagg aagtgttatt 1740 atttattaat taatggtaat tttttttagg aatttttttg tgttatttaa aaaaaatttt 1800 gtgattttat gttagggaat ggtatttttg tatttttttt attgtttttt tttttttttt 1860 ttagtattat ttttgttttt ttgtttttag gaaatggttg gagttttggt gtgtttgggt 1920 tttgttgaga tttataattt ggtaagtggt ataagttggt tgggtttgga gattaggtta 1980 tttatttttg aggtgtttta tgtatgaaat tgatttgtaa gtatttggag taattatggt 2040 tgggataaat atgtttttgg atgatggagt ttgtatttgt tggatgtgtg aatttatgtg 2100 tattttaatt ggtgggtagg gaatataggg ttatgaattg gtatatttat tttgtaggta 2160 ttattttttt tttttagtta taatttgtta gatattttta ttattattat tttttttggt 2220 tatttttaag atggtttata aggtgattgt gttaattttg aatttaggaa attttttttt 2280 atatttgatt gttttgttgt tttttttttt gttaagtttt ttttattagt tttagggaaa 2340 ttggattttt ttgttttttt agtgttaaaa tgtttgagtt ttataaattt tttgagatta 2400 agtttgtttt tttgtttggg ttgtgtttta gtgtttttgg ttttttgggt tttggttgag 2460 tttgttttgt gttgagtttg tggttggagt tttgtttgta ttggggatgg gttttgtgtt 2520 tgggatgttt aggttgggtg tttggtgtgg ggagtttttg gagtgggttt tttggtgttg 2580 gggttttttt tttgtttagg aatttgtagt tgttggtttg gggttatgtt ttggggtttt 2640 tggggttgat ttttgggtta ggaagtttgt gggatgttgt gattgttttt tgttttatag 2700 gtttgggtgt ttggggtgtt agtgggggag gttaggtgtt tgtggtgggg agggtttggg 2760 gtttaatttg gtagaaaaag gttgtggggg aagtgttttt attttttggg gattgaagga 2820 ggaagtagat tttgatttag ttgtattttt ttggagattt gaaggatgat tttagtttat 2880 taaatttttg tggatttaga gttgtgttat ttaaatgtag atttaggggt ttttagaagg 2940 ttatggaaaa gttaaaggga tgtttttggg aagttttttt attaggtttt agtttttttt 3000 tttttttttt ttttttagtt aagttaatgt tttttttttt tggtagggag ttttttttaa 3060 ttttttgtat agtgtttgtg gttggttgta attaattttg gtattataag ttttgttttg 3120 ttttttggag ttgtgttaga ttttgttggg tgtttttttg ttttttagta tggatttggt 3180 gtttgtaggg attggggttt tttgggtttg ggtgggattg tgtggttgag tttgtggttt 3240 tagagttggt agttggggaa agtgggtttg agtttttgtg tttgagaaat gagtgttggt 3300 gttggtgggt ggggttgggg tggagggatt ttttgtgttt ggggagtgtg aggtgttggt 3360 gttgagttgg gtggttgggt gtggggagag ggtgtgggag tggtttgtgt ggtaggtatt 3420 atgtggatgt gtgagtttgg tgagggtttt ggtaggtttg gtttttgttt gggggtgtgt 3480 tgagatggtg ggtgagtttt atgagagtgt tgttgttatt ttgggttaat tttgtggtta 3540 gtttgttggg gtgtgggttg gtgggtgggg gtgagagtgt gtagtgtgtt gtggtgtgga 3600 ttttgtgggt gtttgtttgg tttttggttt gggttttggt gttgttgaaa atggatgagt 3660 gtgtgatttt ttggagggtg gagtgatttg gtttttttta gttgggaaat ttagtattgg 3720 ttaggggggt tttggtggtg gagtgggaaa aggaggtgat tgtgtgggat tgatttgggg 3780 ttattgttgg ggtttgattt tttttgatat gttgtttttt ttttgggagt ttgttgggtt 3840 gtgttggttt tgtggttttt tggggtattt tgttgtttgt gaaagatttg tttgttgagt 3900 ggtgtatgtg ggaggtttgt gtggggttgt tgggtttttg ggtttttggg tgtttgtgtt 3960 ttgtaggagt gttgtttgga ggtgtagatg taattggtgg attgtggagt gaagggttgt 4020 gaggttgtat tttggggttg aatatttgta taatgtgtgg tttgttagtg ttttttgttt 4080 tttttggagg aggaattttt aagatttttt taaaagaaag agtttttggt ttt 4133 <210> 188 <211> 4318 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 188 tatatagttt attagtgata gagtaagatg agatttgaat ttatgttatt gatttttagt 60 atagtttata tttttggttt tatagatgaa gaaattggtt ttaggaggga taaatgattt 120 gtttatttta tttaataatt gtgtattaaa tttattttta taagtgtgtt agtaggatta 180 gttttgagta aaaatgaaag tttagtaaag tttaattttt agtatatttt atgtttttat 240 gattattttt atttgtaatt gatatatatt tttggtattt tgttttttag ttattttaga 300 ttatgtaatt ttggtttgga gatttggttt tatttattgt ttttttattt ttagtaattt 360 aagaggtata aaaaaaattt atttttaaat ggttatatat tgggtagggt aggggtaaag 420 agaagtgatt ggtttttggt tggaagaagg tggtttatta tttagttttt ggttattgtt 480 tttttttaga tttagtgtag atatttttag gttggttttt ttattttttt ttattgaggt 540 taattatttt gttttattgt agggttttag gtttttttat ttaaggtttg ttttgttttt 600 ttagtttttt ttttagtagt tttaagggtt tagtttgtgt ttgattattt aggattatta 660 gattttaaag ttgtggaatt ttataatttt tatgagtata tgtttttttt tagggttttt 720 ttatgtttga aaaggtggtt agtagttttt tgttattttt ttatagtagt agtgtaggtt 780 agttgataag gattataaat ttttagtgtt ttatagttgg tgtttagata gtgtgggtga 840 tgggtagaat aagagttttt gaagtaagtt tagaaatttt aataagttga aatgtagtag 900 agattgtaga ggtataagga aagggattag atatttaaat tttgtagggg tttaggaggt 960 tatgttttaa agtttttttg atttttgttt tttagttttt tttagtggtt attaagtgta 1020 aagttttatg tttggttttt aagttattta agtagttttt tttagagatt tgttgtgtgt 1080 tagatatttt gttagaattt gggaatttta ggaatgaaag gaatataagt agaaaaaaat 1140 tagaagaata taaagagttt gtattattta atttttaaga tatttttttt ttttttgggt 1200 gttagtattt agagagtatt gattttagtg ttaaaatttg gttttttttg aggtagatta 1260 ggagttatta tgtttttagt gaaatggagg tggtaggaat tttattttta attttttttt 1320 ttttttttat gattattttt ttgggggtga gagttgtttg gaagaattat ttgtgttttg 1380 gtattggttt tttgttgagt tttagttgga taaaattagt tgattgttta tattaataag 1440 tgttagagtt tgtgtttagt tgagtgggtg gggagagtag tattgggttg ggttgtattt 1500 ttgtttgggt ttgttagagt agtggataga tagtatttgt tgtgggtttt tttgtttttt 1560 tatttttgtt agagtttgtg gtttttttgt ggagattggg gattatattt gggagtattt 1620 ttttttaatt tttgttattg tagagattgt gttgagttta tttgttaaat gttaatatat 1680 tggaatgtta ggggagggga aaagaaggtt gtatttttat tttttttttt tattatatat 1740 ttatttttta ttgattttgt tatgattggg ttttggtatt tgggtttggg ggtgttaatt 1800 gatattattt tttgttaggt ttttatgttt attttatatt ttgggattgt ttgggggtgg 1860 atttggtttt ggtggttgtt tttggttttg ttgttggttt ttggttattt tgggtgggga 1920 tgtggagagt ggggttggtt ttttttttgt tgtgggtttt tatttatttt tttatttggg 1980 aggggtaata atttgggagt tgtgttatgg aaatgtattt ttttttgtta tttagatggg 2040 aatttgttta tttatgataa ttgttttttt tgtttaggga aagggggtgg gaagatttag 2100 ttttgggttt tgttaattgt tagtaagtta gatggataga tagtagttgt tgtgtgtttg 2160 agtttagttt ttttttgatt ttttgttttt tatttttttg tttgttttat tgatattagg 2220 ggttgtagtg gtgatggtgt tttattttta gtgtttggtt tggagttttt gaggtgattt 2280 gggttgggtt tgttgaggat tttttataat tggtggtttt ttattttttt ttgattggtt 2340 ttgtttttag tgttttaaga gtgggattag gtggttgtta gtgaaagatt tataggagtt 2400 tagatttgag gtttgttagg atgtggagat tgagggtggg tttggttgtt aggaagtgtt 2460 tttgtttggg gtagtaattt ttttttgttt ttttttgtaa tttttaattt gggagggttt 2520 tatggggttt ttttttttat atagtgggtt agtttagtgg ggttgttttt tgttaaagat 2580 ttggtttatt ttttaagtgt tttttttttt agtttttata aaaatttttt tagaattttg 2640 gggaattaat tatgttggtg ggagttttta gtttaggttt atttttttat tttatagttt 2700 ttgattatat aggggagtat gtgggatttt ttaggtttga gaattttttt ttaagtttgg 2760 atggagtttt aagagtggtg agaaggatta gattgatttg aagagttgtt ttttttagtt 2820 tgtttttttt ttatattttt ttattttagt ttttattgat ttgttttttt ttgtgtttgt 2880 ttagtggggg gtgaaggaga ggataattat ttttattttt ttttttaatt tttatatata 2940 ttttttgttt tttaaggtgg agttttttgg gaggtgggta gttttgtaga tttttttgtt 3000 ttaaggtttt gtaaaggtag agtttttttt tgttagtttg gggtttttta gttttttgtt 3060 gtatttgtta ttttttttta tatttttttt attttttttt gtagtatatt tggatataga 3120 ttattttttg attttgtaaa aaataaaata aaataaaata aaataaagtt ttgagaaatt 3180 tttaaatatt tgtgtgtgga tgaattatag tttatagttg tttttatatt ttttattata 3240 attggttttt tttttaattg tgggaggtaa ttgtttttaa gttgggttat agttggggga 3300 attgaggatt ggggggaatt gaatgtgggt tttgaatgtt tttgtaaggt tttttttatt 3360 ttattttata gaaagtaggg aagtgagtaa attttttatt ttttttgatt ttagaaagtt 3420 tgtttgttgt ttttggagtt agtatttgtt ttttttttgt ttattttatt ttttaatgaa 3480 ggtattattt gggagtggta ttatagtttt aagatggagg tatggagggt agtagaagtt 3540 gagttatagt ttttgtgtat tttttggatt tttttaagga gggtatgtgg aagagaaagt 3600 ttgttttttt ttgggagtat gggttattgt tttttaggtt tttttttttt ttaatatgga 3660 ggaaaaattt taaaataagt ttgtgtgtgt tttatttttt tagttttttt tttatgattt 3720 aataaaatta ttattattga gggttaattt ttagggtttt gtttgatgtt tataggttat 3780 aaaaggaaga attttttggg ttggttattt ggggatggga gggtgaggag tagtttatgg 3840 gaggttttgt ttttgtgaga aaggatttgt atgtttaaga ggttaatata gttagtttag 3900 ggtttttttt tttttagatt tttagttttg tattaggtta tagagaggaa atggtaaaga 3960 gtagtaaata ttatgtaaaa gggtaaagga gtttttaagt taggagttgg gagtttttgg 4020 gaaaagaaaa gggaagaata tgtttaaatt tttgtttata gttgggtgtg gtggtttatg 4080 tttgaaattt tagtattttg ggaggttgag gtaggtagat tatttgaggt tgagagtttg 4140 agattagttt gattaataag gagaaatttt atttttatta aaaatataaa aaataaatta 4200 gttgggtgtg gtggtatatg tttgtaattt aagttattta ggaagttgag gtaggagaat 4260 tgtttgaatt tgggaggtgg aggttgtggt gagttgagat tatattattg tattttag 4318 <210> 189 <211> 4318 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 189 ttagagtgta atggtgtgat tttggtttat tataattttt attttttagg tttaagtgat 60 ttttttgttt tagttttttg agtagtttga attataggta tgtgttatta tgtttggtta 120 atttattttt tgtattttta gtagagatgg ggtttttttt tgttggttag gttggttttg 180 aatttttgat tttaggtgat ttgtttgttt tggtttttta aagtgttggg attttaggtg 240 tgagttatta tgtttagttg tgggtagggg tttagatatg tttttttttt tttttttttt 300 aggagttttt agtttttagt ttgggagttt ttttattttt ttgtataata tttgttgttt 360 tttgttattt tttttttgta gtttgatgta gggttggaag tttggaagag aggaagtttt 420 ggattagttg tgttgatttt ttagatatgt aaattttttt ttatgaaagt agagtttttt 480 atgagttgtt ttttattttt ttgtttttaa ataattagtt taaagaattt ttttttttgt 540 ggtttgtggg tattaagtaa agttttggaa attagttttt agtgatgata attttattga 600 attatgagag aaggattgag ggagtggagt atatgtaagt ttattttgga gttttttttt 660 tatgttaagg gggagaggaa tttagaagat aatgatttat atttttagag aaaggtagat 720 tttttttttt atatgttttt tttggggaag tttagggggt gtataaggat tgtggtttgg 780 tttttgttgt tttttatgtt tttattttgg ggttgtagtg ttatttttaa atagtgtttt 840 tattggggga tagagtggat aagggaggag taggtgttga ttttaggagt agtaagtagg 900 ttttttgaag ttagggaaaa tgagagattt gtttattttt ttattttttg tgaagtgggg 960 tggaaagggt tttgtagaag tgtttaaaat ttatatttag ttttttttgg tttttaattt 1020 ttttaattat aatttggttt aagagtagtt gttttttatg gttgggggga gggttaattg 1080 tgatgaggga tataggagta attgtgaatt gtaatttgtt tatgtatagg tgtttggaga 1140 ttttttaagg ttttgttttg ttttgttttg ttttgttttt tgtggggttg aggggtggtt 1200 tatgtttaga tatgttgtgg ggaaggatga aaggagtgtg ggaggaggtg gtaaatgtgg 1260 tagggagttg gaagatttta gattgatagg aggaaatttt gtttttgtaa ggttttaagg 1320 tagaaggatt tgtgaggttg tttgtttttt aggagatttt attttaaggg atggagggtg 1380 tatgtgaaag ttggggggag aagtgaaggt agttgttttt ttttttattt tttattaggt 1440 aagtgtagaa ggaagtaggt tggtggagat tagggtagag gagtgtagga gaggagtaaa 1500 ttgaggaggg tggttttttg agttaatttg gtttttttta ttatttttga ggttttgttt 1560 aggtttggag gagggttttt aagtttagga aattttgtgt gtttttttgt gtgattggga 1620 attgtgagat gggggagtag gtttgagttg ggagttttta ttagtatggt tgattttttg 1680 gagttttgaa agagttttta tggagattgg gggaaggggt gtttgaaggg tgggttaagt 1740 ttttggtaga aagtagtttt attgggttga tttattgtgt ggaggaggag gttttgtagg 1800 gtttttttgg gttggaggtt gtagaggagg gtggaggagg attgttgttt tgggtgggag 1860 tgttttttgg tggttgaatt tgtttttagt ttttgtattt tggtgggttt tgagtttggg 1920 tttttgtagg ttttttgtta gtagttgttt gattttgttt ttgggatgtt agggatgagg 1980 ttggttggga gagaataggg ggttgttgat tgtaaaagat ttttgatagg tttagtttgg 2040 attattttga gggttttgga ttgagtgttg ggggtggggt gttgttgttg ttatggtttt 2100 tggtgttggt ggagtgagta gggaggtaga gggtggggga ttgaggagga gttgagtttg 2160 gatatgtagt agttgttgtt tatttgtttg gtttgttggt agttggtagg gtttgaggtt 2220 aggttttttt gttttttttt tttaggtggg aagggtggtt gttatgggtg ggtggatttt 2280 tgtttgaata gtaggggaag atgtattttt gtggtgtggt ttttgggtta ttattttttt 2340 taaatgggga aatggatgga gatttgtggt gggggaggag ttaattttat tttttgtgtt 2400 tttgtttaag gtggttggag gttagtggta ggattaggag tgattgttag ggttaaattt 2460 atttttaggt agttttagag tgtggagtgg gtatggggat ttggtgggaa atagtgttga 2520 ttagtatttt taggtttgga tgttagggtt tagttgtggt gaggttagtg aagggtgggt 2580 gtgtggtggg aaaggagagt agaagtgtaa tttttttttt tttttttttg gtattttagt 2640 gtattaatat ttggtaggtg ggtttggtgt ggtttttgtg gtgatgagag ttggggaaag 2700 atgtttttaa gtgtagtttt tggtttttgt gggggggtta taggttttgg taggagtgag 2760 ggaatgagga ggtttatgat aggtgttgtt tgtttgttgt tttgataggt ttgggtggga 2820 atgtggtttg gtttagtatt gtttttttta tttatttagt tggatgtgga ttttgatatt 2880 tgttagtgtg agtaattgat taattttatt tggttggggt ttagtaggaa attaatgttg 2940 aggtgtgggt agtttttttg ggtgattttt gtttttggga ggatagttgt ggggagagga 3000 agaggggttg ggggtgggat ttttgttgtt tttattttat tgggggtgtg gtggtttttg 3060 atttgtttta gagaggattg aattttggtg ttaaggttgg tattttttgg gtattggtgt 3120 ttagagaaga aaagggtatt ttggaagtta ggtagtataa attttttgtg tttttttggt 3180 ttttttttat ttatgttttt tttatttttg aagtttttgg attttagtag agtgtttgat 3240 atgtagtagg tttttagaaa agattgttta aatgatttga aaattaggta tagaattttg 3300 tgtttggtga ttgttagaga gagttgaaag gtaggaatta aaggggtttt gaagtatagt 3360 tttttgaatt tttgtaggat ttgggtattt aatttttttt tttgtgtttt tgtagttttt 3420 gttgtatttt agtttattag aatttttgaa tttgttttaa gggtttttat tttatttgtt 3480 atttatatta tttaggtgtt agttatgaga tattagggat ttgtaatttt tgttagttgg 3540 tttgtattgt tattgtggag aagtggtagg gagttgttgg ttgttttttt agatgtgaaa 3600 agattttaga ggagagtata tgtttgtaaa aattatggga ttttatagtt ttgaaattta 3660 ataattttgg gtgattaaat atagattgga tttttggggt tgttggggaa ggggttaggg 3720 gagtggggta gattttaggt gggagagttt ggggttttgt aatgggatag agtaattagt 3780 tttagtggga ggagatgagg aagttagttt gagggtgttt atattgagtt tgaggagaaa 3840 taatagttaa gagttgggtg gtaaattatt tttttttaat tggaaattag ttattttttt 3900 ttgtttttgt tttgtttagt atgtggttat ttggagatgg attttttttg tattttttga 3960 gttgttgggg gtggagggat agtaggtgaa attaggtttt taagttaaga ttgtatggtt 4020 tggagtgatt gggagataga atattaaaag tatgtgttag ttgtgggtga gagtaattat 4080 gaagatatgg ggtatgttaa aagttaaatt ttgttaaatt tttatttttg tttagagttg 4140 gttttgttga tatatttatg gaaatgggtt tggtatatag ttgttgaatg aagtgggtaa 4200 gttatttatt ttttttaggg ttagtttttt tatttgtaaa attaggggtg taaattgtat 4260 tggaagttaa tgatatgagt ttaagtttta ttttgttttg ttattgatga attgtgtg 4318 <210> 190 <211> 3324 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 190 tttaatttta atttttttat aggaataatg ttaattagtg aggtttaatg agaatttttt 60 ttaggaagtg tagtttggta ggggtggttg gatttgggta aatgtagttt tgggtgggag 120 tagggttatt tttgtttttg agtggttgga ataaaaatgt ggattgtatt tttttttttt 180 ttttatttaa agtgtttagt tttgaagata aggtggaggg aggagagaga gggtggaggt 240 gtaaatttaa tttaattttt gtgtgtgttt ttgaggtggt tggttgtttt tgttttgttg 300 tgttttttta ttaaggaagg tttttttgtt aggggttgtt aatgtttgtg gtttttggtt 360 agatggtgta tttgagaggg atattttgtt tttttttggg agggatttgg gtttgttgaa 420 gtgggtttaa ttttgtaaat tgtgttttaa ttttttgtgt tgtgttgggg aatttttttt 480 tgatatttaa tgttttttgt ttttatattt ttaaatatag tttatttttt tttttgtggt 540 ggttgtggta atttgagttt ggtttttgtt ttgttgttag agaatgtttt ttttgttggg 600 atgtggtgtt gagtttgttg tatattgagt ggttgtggta taatattgtg gtgttgtgtg 660 tataattatt gttttttagg atttgtggtg tgtattttgg gagtggggtg tgttttgtga 720 ttttgggtgt ttagggttag atatattttt tgggtgtttt gtggttttta tagtgtagtt 780 tttattgttt tttttttatt tttgggtata tttatttgtt ttttgtttta gtttatttgg 840 tttagggtgt agttgttttt ttgtgttttt ttttttagtt ttggtaaagg aagttttttt 900 tgtgtttttt tttttagaat tgtttttagt tttttgtttt tttaattgta gtttaatggt 960 tggtggtagt agttggagaa ggggggtggt ggtttgggtt ttggaaatgg tttgattgtt 1020 gggatttggg ttggattttg tatttgggtt ggaagtgagg tggagatggg tggttgggat 1080 ttgtgagtga gtggggtggg tggtggtgat agttttatag ttttagttgt tgttgttgtt 1140 gttgttgttg tggttgtttg gggagagggg ttggtattat tgtggtgtgt tattgtttgg 1200 tttgggggtg ggggtggtta ggaggagggt ttaggtgagt agtggtggta gtggtggtgg 1260 tgttgtggtt tggaggaagg gggagggggt attgggtatg gggaggtggg agagggggtg 1320 ggattgggta tggggtgggg gtggggggga ggggagtgta gggagggtgt aggtaggggg 1380 agtaggagga gtagtaggag gaggtggtgg aggggtgggt gagagggagg agtgggtatg 1440 gggggaaggg gagagaggaa aaggaggtat ttagggagag gggagaggag aaaggaggga 1500 gagaggtgtg gggggagaag aggaggaagg agggggagtt gggttaggta gggggggata 1560 agggtgtgtt ggatgtgttg ttgtgtgttt tggtggggag tgtgttttta agggggaagt 1620 gttttgagga agatttttgt atggggttga gtttggaaag aaggtgttgg gatttgtgtt 1680 tatttattgt ttttggaggt tgtggttttt gggtttggtg ggggttgggg ggagagggta 1740 tttggtgggt tgtttgtggt taggttagga gagggagatt tggtttaaat aaagtgattt 1800 aggtattttt aggaattttt ggtgtttggg gtttttttgg gtagtttttg atttttatgt 1860 gttttttggg tttttaggga tgtgggtatt tgtggggtgg ggttgttggg ttttggggtt 1920 tggttttttt gggtggttgg agtgagattt tgggttggga aagttaggta tgtggttggt 1980 ttttggttgt atttttgttt tatttttatg gtagggtttt tagtgtttga ttaagtttaa 2040 gtttgagttt tttggtgtgt tgtttattgg ttgttttttt gtgttttttt ttttttttta 2100 tttgtattgt tttgtttttt attttttttt tgtttttttt ttattattta gtttatattt 2160 tttttgtttt tttttttgtt ttttgtgggt atttgagtgt ttgggaggtg tttatttgtt 2220 tgatttaaat atttatgtga tttttagtgt ttgttgtttg tgtgtttgtt tttgttttgt 2280 tgttggttat tgtgttttgt tagtttatat tgggttgggt tttgatggtg tgtgagttat 2340 agttgtaaag taataggata attttgggga tgttgtttta gtttagattt gggtatgtat 2400 tgtttgtgga gatggtattg ttggggaggg gagttatgtg gattttagat gtggtttttt 2460 aggtggatag atttttgttt ggggtgtagg aggaggtagg attggtattg tggggtggga 2520 gttttggatt tttgagtaat tttggatttg gtttgaaaag taatattttt attattaaat 2580 tgtagaatta gattttgatg gagaaaatgg gttaggggat ttatttttat tttatttttt 2640 taaatttaga ttttttgtta ttatagatta gttttgaaaa aagtttgtgt tttaataagg 2700 atggggaatt gtttttgtgg aattttgtgg ggaaattgtt aaaaaaaaaa aaaaaaaaaa 2760 aaaaaaaaat aattaaaaaa aaattttgat aaggatttta ttttttgatt tttttggttg 2820 tatttgaaga ggaagggtaa tttttattga ttttttatgt tattatttat ttatggtgga 2880 attagtagag aagagaaaat gagatagtta tagtgattgt ttgtaatttt gaaatagatt 2940 gtttttaatt ttttaatttt ttttttgtaa aaagtttttt tttttttttt ttttgaaagt 3000 tttgtattgt gaataattta tggtaaataa ggtttttttt atagttgtga gtgtgaagta 3060 taattttata ggtttagagt ttagtgttta tttgttagaa aaataaaatg atgataagat 3120 attatattag tgttatgtag gttttttttt gtatatgttt aagattttgt tgttaataga 3180 aaatttatat ttttttttta aaagagggtt taggtatatt tatttatttg tattttttat 3240 ttttgaaatt aaatgtgttt ttaaattaat ttattttttt tagtttattg gattttttta 3300 tttttggtga tgtggggtag gtgg 3324 <210> 191 <211> 3324 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 191 ttatttgttt tatattatta aggatgagaa gatttagtaa attggggaga gtgaattggt 60 ttgaaaatat atttgatttt aggaataaaa ggtgtaaatg agtaaatgtg tttaaatttt 120 tttttaaaaa gaaagtgtga gttttttatt gatagtagag ttttgagtat gtgtggaagg 180 aagtttgtgt ggtgttaatg tgatgttttg ttattatttt atttttttga tgggtaaatg 240 ttgggttttg aatttgtggg gttgtatttt gtatttgtgg ttgtagaggg agttttgttt 300 attatggatt gtttataatg taaagttttt agaggaagaa agaaaaaagg ttttttatag 360 aaaaaaagtt ggagggttaa aggtagtttg ttttaaaatt gtaaataatt gttgtggttg 420 ttttgttttt ttttttttgt tggttttatt gtgaatgaat ggtagtgtaa agagttagta 480 gaaattgttt tttttttttg gatgtgatta gaggaattag gaggtgggat ttttattagg 540 gttttttttt agttgttttt tttttttttt tttttttttt ttttggtaat ttttttatag 600 aattttatga gggtagtttt ttatttttgt tgaagtataa gttttttttg aggttgattt 660 gtggtagtgg agggtttgga tttggagggg tggggtggga atggattttt tgatttattt 720 tttttattgg ggtttaattt tgtggtttgg tgatgagagt gttgtttttt gggttgagtt 780 tgaggttgtt tggaggttta gggtttttat tttgtgatgt tagttttgtt tttttttgtg 840 ttttgggtaa gggtttgttt gtttggggga ttgtatttgg aatttgtgtg gttttttttt 900 ttggtggtgt tgtttttatg gatagtgtgt gtttgggttt gggttggagt gatgtttttg 960 agattatttt attattttat aattgtggtt tgtgtgttgt taggatttgg tttggtgtgg 1020 gttggtggag tataatgatt ggtggtgggg tgggggtggg tatgtgggtg gtgggtgttg 1080 ggggttgtgt agatgtttgg gttgaatagg tgagtgtttt ttggatattt gggtgtttgt 1140 ggggggtggg gaggagggtg gagggggtgt aaattaagtg gtgggaaaga gataaaggaa 1200 gagtgaagag tgagatggtg tggatgggga agggggaggg gtgtggaggg gtagttggtg 1260 ggtagtgtgt tgaggagttt gagtttgaat ttgattaagt attgggggtt ttgttgtggg 1320 ggtggggtgg gggtatggtt gagagttggt tatgtgtttg gtttttttag tttggggttt 1380 tgttttggtt gtttggggga gttgaatttt gaggtttggt agttttgttt tataagtatt 1440 tgtgtttttg gggatttgaa agatgtatgg gggttgaagg ttgtttgaag gggttttggg 1500 tgttgagagt ttttgagggt gtttgagtta ttttatttgg gttaagtttt ttttttttgg 1560 tttgattgta gatagtttgt tgggtgtttt ttttttttag tttttattgg atttagagat 1620 tgtagttttt gggagtgatg ggtaggtata gattttagtg tttttttttt gggtttagtt 1680 ttgtgtaagg attttttttg aagtgttttt tttttaagag tgtgtttttt attgaagtgt 1740 atggtggtgt gtttagtgtg tttttatttt tttttatttg gtttagtttt tttttttttt 1800 tttttttttt tttttgtgtt tttttttttt tttttttttt tttttttttt ttgggtgttt 1860 tttttttttt tttttttttt tttttgtgtt tatttttttt ttttatttgt ttttttgtta 1920 tttttttttg ttgttttttt tatttttttt gtttgtgttt tttttgtgtt tttttttttt 1980 ttgtttttgt tttgtgtttg gttttgtttt tttttttgtt tttttgtgtt tggtgttttt 2040 tttttttttt tttgggttgt ggtgttgttg ttgttgttgt tgttgtttgt ttgggttttt 2100 tttttggtta tttttgtttt tgggttgggt agtgatgtgt tgtggtggtg ttagtttttt 2160 tttttgggta gttgtggtgg tagtagtagt agtagtagtt ggagttgtgg ggttgttatt 2220 gttgtttgtt ttgtttattt gtggattttg attgtttatt tttgttttgt ttttagttta 2280 ggtatggagt ttggtttgga ttttggtgat tgggttgttt ttggggtttg ggttgttgtt 2340 tttttttttt ggttgttgtt gttggttgtt gagttgtggt taggggggtg aggggttggg 2400 ggtggttttg gggagggggg tgtaggggga gttttttttg ttggggttga gggagggggt 2460 gtgggggagt ggttgtgttt tgggttgagt gggttggggt ggggggtggg tgagtgtgtt 2520 tgagagtgga gggggggtga tgaaggttgt attgtggggg ttgtggggtg tttaagaggt 2580 gtgtttggtt ttgagtgttt agggttgtgg ggtgtatttt atttttgggg tgtgtgttgt 2640 gggttttggg gggtggtgat tgtgtgtgta gtgttgtggt attgtgttat ggttgtttgg 2700 tgtgtagtgg gtttggtatt gtgttttggt gagggaggtg ttttttggtg gtggggtggg 2760 ggttgggttt gggttgttgt ggttgttatg agaagggaag tggattgtgt ttggggatgt 2820 gaggatggga agtgttgagt gttagggagg ggttttttgg tgtggtgtgg ggagttgaga 2880 tgtggtttgt agagttgagt ttattttagt aggtttgggt tttttttggg aggggatggg 2940 gtgttttttt taggtgtatt gtttgattgg aagttgtggg tgttggtggt ttttggtgaa 3000 ggggtttttt ttaatgaggg gatatggtgg ggtgggggta gttggttgtt ttgagggtgt 3060 gtgtaggggt taagttggat ttatattttt gttttttttt tttttttttt attttgtttt 3120 taaggttgga tattttggat agggaggagg ggggagtgta atttgtattt ttattttagt 3180 tgtttgggag tagaagtgat tttgttttta tttggagttg tgtttgtttg agtttggttg 3240 tttttattgg gttgtgtttt ttgggggaag tttttattaa gttttgttaa ttagtattat 3300 ttttgtagaa aggttaaggt taga 3324 <210> 192 <211> 4431 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 192 ttatagttaa tgtttaatat tttaattttt ttaggtttag aattttttta ggattgattt 60 tgtgtttatt tgtgttaaaa tgtgttaaat tagataggaa ggggaagtat aaaatttaat 120 ttataattta aggtaagaat ttgagttttg gtttgaaaaa tgaaaagtta tggagtgata 180 taatatattt tgatttttta aataattaag atatttaatt ttaaagatat tttttaaata 240 agagatagtt taagtttaga ttgtttatag ggtattagtt tttagaaaaa tgttatggtt 300 agagatagat ttgaaatgga gatatgtttt aagtttagag ttttggagtt attattagat 360 agtatgttag gagaagataa tgagaaaaag gagagattta tattaatttt gttttatttt 420 ttttttggag gtatatagtt ttgggttgat ttttgggatt agttgattta ttggttgtgt 480 ttttttggtg tttgttgttt gtttggaaag gtagttgttt gttgaagagg aaaagttggg 540 aatgtaattt ttaattttta ggataatgtt tagtattatg ttttattttt aatttgtttt 600 ttttaaatgg aaatagataa ggttattttg aaattattta gttatttatg aaatagagtt 660 tataattatt tttttttttt ttttaatatg attagaaggg tgatttttta aatgtggttt 720 tttttatagt tatgtttgga ggggtatttt ttagtgtttt agtaagtgtt tttagtgata 780 ttagaatgtt agttaagatt taagatatat ttttttagtt gttttttgtt atttgttata 840 gaaaataatg ttgttgtatg tttttaaaat gttgttttat aagtagattt ggtttttagt 900 aattggtgag gaaaagttat tggaattaaa tattatttat atagttattt agagtggagg 960 ttattgtttt attttggtag aggtatatgg gggtagtagg taggattgag aggggtttga 1020 aggtgttgta ggaggagagg ttgggtgtag atggtttggt tttaaattat atttagtgtt 1080 aggaaatgta aggtttggga tgaattttta agaagttgtt gttagggata gggaggttgg 1140 gagtagggag tgatgttata ggaattttga atttttttga gttttttttt aattaagtta 1200 aggttgagta aggggtgttt tatgtattgt aagtttttaa tttaatattt tggtaatgat 1260 aaatagaatt ttttgatttt aaaggttgtg aagtatgtgt tttttggggt tttgagtgag 1320 tttttaaatt tttgtgttga ttttttaaat ttattttttg tttttttgga atgggtgtat 1380 gtgaggtatg gattttagga aatttttgtt gtgatagttt atttatggtg gaggtggagg 1440 tttgggatgt tggatggaga aaggtggtta gtggagggag gaggggtagg ttggtaatgt 1500 ggtggttttg gatgtttgag ttgtttggat gaagtgttgg ttttattttt gtttttggtt 1560 gttgtggtga ttttatttga gttgtgattt tttttaagat tttagggttt gggttttttt 1620 gttgtgttgg ttttagggtg ttatttttgg atgtttagat gtgttttgga ttttgtgttg 1680 ggattttgaa tattgttgtg tttttatttt gtgttgagtg tgtttggttt tgttttggtt 1740 gtagtgggta tgagttttag gtgggtggtg gggatgtagt gtttgtagtg tgattggtgt 1800 agttgttgag gtatggggtg tgttgtttgg attttgattt tgtggtgtta ggagaggtgt 1860 gggtgttggt tggagagttg tattttttgt tttgttgagg ttgttggtta tgggtgtgtt 1920 tgttttaagg gttgggtgga ggatttgttt tggattttag aggatgtggg tggggaaggg 1980 ataaggatag ggataaggga ggggatgtga attgggttga ggtgtgggtt agttttggtt 2040 tgggaaggga ggttgttggt agggttatta ggattttttt tggatatgga aggatgggtt 2100 tgttttggat ttagggattg ggaaatgtgg gtttttttag aatttgggga agtggggaga 2160 gggtttgttt tggagtgtgg agggagattt attttgggtt taggataatg ggggtggggg 2220 taggatggga atgagggggt atttttggtg tagggagggg agatggagaa gtagtagggg 2280 gtttgttttg ggtttgtggg ttggggatta tgaagtgtag gagggtattg tttaggattg 2340 ggatgaggag ggagaggggt ttgttgtggt tttggataga gggggaggga aagtgtgttt 2400 tggtttgaga ggaggagtag gagggttagt tttggatttg ggtttaggaa gttgggaggg 2460 aggtttggat ttgttttaga gatagggtga tgaagatttg tttaagtttt ggagtggagg 2520 gaaggatgtt ggtggtgggg gaagaggttg gttatggata gggaaaggga gtttgttttg 2580 tagggtggat gggtggtttt ggggaaggga gaggttgtga tgtggggggt gtttggtttg 2640 agtggggttg tttattttgg gtttgtagag ttatttttgg aatttgttta ttattgttgt 2700 gttggttttg gttggatttt gggtggtttt tgttttttgt agtgttgtgt ttgggtttgg 2760 ttgaggtgtg gggtggatgt ggaggtatgg ttggagtttt tgtgttgttg tagggaggtt 2820 ggttagtgaa gtttggagtg ttgagtgggt ggtgggtagg tgtgtggggt aggtgtgtgg 2880 ttttgagtat gttttgtaag tggtgtgttg ggtagatttt agatttggga gtgggtgttt 2940 gggtgtatgg atagatgtgg gtatgggggt gtgtggtttt ttgttgttta ttgatattta 3000 gtgttttgtt ggttatggtt gttttgtgtt gtatatgtgt ttagggtgtt gtgagttttg 3060 ggtttattgt gtgttgtggg tggggtgggt ggggtggagg tggtttaatt tttgtgtggg 3120 tgttgtattt tgtttgaggt gtgttttttg ttggtggggt gatttgttgt gtttgggtat 3180 ttaagaaatt ataagttttg aaaggtatgg tggggaggtg gtgtttaggg tttggtgttt 3240 tgggttgtgt tgtggtgttg tgtattgtgg gagttgtagt ttatttgatg gtggtggagt 3300 gtgttgttgg ttgttaggtg atgatgttaa atagttgtgg tgttttgttt attgggagtt 3360 gatggatgat gattgttaat attttagttt tagttggttt aggaaattgt tgtggtggta 3420 ggtggtggtg gtaggagggt ttggttgttt tgagtgtttg ttaggtatgg gggtgggata 3480 ggtgtggggt gatgtgttgt tgatttttat gatttgttgg ttggtttttt tttgtttgtt 3540 gtttattttg ttttttttaa atattttttt tgtttttttt ttagtttttt gatgaaagtg 3600 aatggtgttt tttttttttt ttttaaatta ttattattag tggtgtgttt taaaaagata 3660 tttttttgtt tttgttattt tttttagtgg tgttttaatt tgtattttaa aatgtttatt 3720 ttaatttgag tatttgttat gtgttaagta gagagttaaa aatttatatg tggttttatt 3780 taaatttttt attgatagtt agagaagtag gtataatgag gttggtgtgt tttggttgtg 3840 ggggttgtat ttagattatg gtggatttgg gttggtttga ttttatagtg ttgtattttt 3900 ttttgttgta ttattattat gtttttggtt tgttgtgaaa tgtgtagatg taagatatag 3960 gagatggaag ttatgttttt tttggtttag aattgagaag tttgatttgt ttttgtttgt 4020 ttttattggt tagtgttagg tgtttagaaa ggtttgtggg ttttatgatt attttatttt 4080 aatagatgtg atgtgagttt aggtgtgttg gtatttaaga ttttttttag ttgggggtag 4140 ggtttatgtt tatttttgag taattgattg atttttttta tttttttttt tttattattt 4200 agttgatttt ttgaagggta aaattttttt ggagtttttt tttattttta attttttttt 4260 atttgttttt tttggaaatt atttttatta gatttttatt taattatttt tttgaagttt 4320 tttattaaag ttatttttga ttttgatgtt gtaaaatttg atgattgggg ttagtgttta 4380 tttttttttt gaattgttat tattatgtga tttagttgat tgtgtttttt t 4431 <210> 193 <211> 4431 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 193 gagagggtat agttggttgg gttatgtggt agtgatagtt taaggaagag atgagtgttg 60 attttgatta ttggattttg taatattaag gttaaggatg attttgataa agagttttag 120 aggagtggtt gggtgaaaat ttgatgggag tagtttttag aaagaataag tgggaaggaa 180 ttggagataa ggggaaattt tagaggggtt ttgtttttta gagggttgat tgggtggtag 240 gaagaggaga gtagggaaaa ttaattagtt atttaaaaat aaatatggat tttattttta 300 attaagagaa attttagatg ttagtgtgtt taggtttata ttgtgtttgt tggaataaag 360 tggttatgga gtttatggat ttttttgagt atttggtatt ggttagtgag gataagtagg 420 aataggttag attttttaat tttgaattga ggggggtatg atttttattt tttgtgtttt 480 atatttgtat gttttataat aagttagaga tgtggtggtg gtgtggtagg gaaaagtgta 540 gtgttgtggg gttaggttga tttagatttg ttgtgatttg gatgtaattt ttatagttag 600 ggtatgttgg ttttgttgtg tttgtttttt tggttgttaa tgggaagttt aagtgaggtt 660 atgtgtgggt ttttagtttt ttgtttgata tatagtaggt atttagattg aggtgagtgt 720 tttaaggtat aaattagggt attattgggg ggagtagtga gggtggaaga gtattttttt 780 agaatgtatt gttgatagtg gtgatttaaa aaaaaaaaaa gaggtattgt ttatttttat 840 tggggagttg ggaagaagat agaagaggtg tttgggagaa gtaagatgag tagtgagtga 900 gagggaattg gttggtaggt tatgaaaatt ggtggtgtgt tgttttgtat ttgttttgtt 960 tttgtatttg gtgggtgttt ggggtagttg agtttttttg ttgttgttat ttgttattgt 1020 agtagttttt tgggttagtt ggggttaagg tgttggtagt tgttgtttgt tagtttttgg 1080 taggtaggat gttgtggttg tttggtgttg ttatttagta attggtggta tgttttgttg 1140 ttattgggtg gattataatt tttataatat atagtgttgt ggtgtggttt gggatgttaa 1200 gttttgggtg ttattttttt gttatgtttt ttgggatttg tagttttttg gatatttggg 1260 tgtggtgggt tgttttgttg gtagggagtg tgttttgggt ggggtgtggt gtttgtgtag 1320 ggattgggtt gtttttgttt tgtttgtttt gtttgtagtg tgtggtgggt ttggggtttg 1380 tggtgtttta ggtgtatgtg tggtgtgggg tggttgtgat tagtggagtg ttgggtgtta 1440 gtgagtagtg aggagttgtg tgtttttgtg tttgtgtttg tttgtgtgtt tgagtgttta 1500 tttttgggtt tgaggtttgt ttggtgtgtt gtttgtagag tatatttagg gttgtgtatt 1560 tgttttgtgt atttgtttgt tgtttgtttg gtgttttggg ttttgttagt tagttttttt 1620 gtgatagtgt gggggttttg gttgtgtttt tgtgtttgtt ttgtgtttta gttgggtttg 1680 ggtgtagtgt tgtggagggt gagggttgtt tggagtttgg ttagggttgg tgtggtgatg 1740 atgaataggt tttgaaagtg gttttataaa tttaaggtga gtggttttgt ttgggttgga 1800 tgttttttgt gttgtggttt tttttttttt taggattgtt tgtttgtttt ataagatgga 1860 tttttttttt ttgtttgtgg ttggtttttt tttttattgt tgatattttt ttttttattt 1920 taagatttgg atagattttt attgttttgt ttttgaggtg gatttgaatt ttttttttgg 1980 ttttttaagt ttgggtttag gattgatttt tttgtttttt tttttgggtt ggggtgtatt 2040 tttttttttt ttttatttag ggttataatg ggtttttttt tttttttatt ttggttttgg 2100 atggtgtttt tttatatttt gtggttttta gtttgtgggt ttggagtaga ttttttatta 2160 tttttttgtt tttttttttt gtattaggaa tgttttttta tttttgtttt gtttttattt 2220 ttattgtttt gggtttggaa tagatttttt tttgtatttt agaatagatt ttttttttat 2280 ttttttaggt tttgagagaa tttatatttt ttaatttttg ggtttagggt agatttgttt 2340 ttttatgttt agagaggatt ttgatggttt tgttaatggt tttttttttt gaattaggat 2400 tgatttatat tttggtttag tttgtgtttt tttttttgtt tttatttttg tttttttttt 2460 atttatgttt tttggaattt gggataggtt ttttgtttgg tttttggggt gagtgtgttt 2520 gtggttagta gttttggtgg ggtgggaggt gtggtttttt agttggtgtt tgtgtttttt 2580 ttagtgttgt ggggttgggg tttgggtggt gtgttttgtg ttttagtggt tgtgttagtt 2640 gtattgtggg tgttgtgttt ttgttgtttg tttggggttt gtgtttgttg tagttggagt 2700 agggttgggt gtgtttggtg tgggatgaag gtgtggtggt gtttaggatt ttggtgtagg 2760 gtttagggtg tatttgggtg tttgagggtg gtattttggg gttggtgtag tggggaggtt 2820 tgggttttga gattttgggg gaggttatgg tttgggtggg gttattgtgg tgattaaggg 2880 tgggagtggg gttagtgttt tgtttgggta gtttggatgt ttgaggttat tgtgttgttg 2940 atttattttt ttttttttta ttggttgttt ttttttgttt agtgttttag gtttttgttt 3000 ttattgtggg tgagttgtta tggtagaggt tttttgaaat ttgtgttttg tgtgtgttta 3060 ttttaggaag gtgggaggtg ggtttggaag attggtatgg aggtttgagg gtttatttag 3120 ggttttgaag ggtgtgtgtt ttatggtttt tgaggttggg gaattttgtt tgttgttgtt 3180 ggagtgttgg gttgagggtt tatggtatat ggggtgtttt ttgtttggtt ttggtttgat 3240 tgggagggga tttgggggga tttagggttt ttgtggtgtt attttttgtt tttaattttt 3300 ttgtttttag tagtgatttt ttaagggttt gttttgagtt ttgtgttttt tggtgttggg 3360 tgtggtttgg ggttgagttg tttgtgttta gttttttttt ttgtggtgtt tttgagtttt 3420 ttttggtttt gtttgttgtt tttatgtgtt tttgttgggg tagggtggtg gtttttgttt 3480 tggatagttg tatgaatggt gtttggtttt agtgattttt ttttattagt tattgaaaat 3540 taagtttgtt tgtaaaatgg tgttttgggg gtgtgtagta gtattatttt ttgtgataaa 3600 tggtgggagg tagttggaga aatgtgtttt aggttttaat taatattttg gtgttgttga 3660 aggtatttgt tgggatatta ggggatgttt ttttggatgt ggttgtggaa gaggttgtat 3720 ttgggggatt atttttttaa ttgtgttgaa aaggaaggaa aaataattgt agattttgtt 3780 ttatgagtag ttgagtaatt ttaggatggt tttgtttgtt tttgtttagg gaagataggt 3840 taaaggtaga atatggtatt agatgttgtt ttgagaatta ggaattgtgt ttttaatttt 3900 ttttttttag taggtagttg tttttttagg taggtggtgg gtattaagag ggtatagtta 3960 gtgaattagt tgattttagg gattagttta gagttgtgtg tttttggaga agggatggaa 4020 taggattgat gtggattttt tttttttttt gttgtttttt tttggtatgt tgtttggtag 4080 tagttttaga gttttggatt tgagatgtat ttttatttta gatttgtttt tggttatagt 4140 atttttttgg gagttggtgt tttgtgggta gtttgaattt gggttgtttt ttatttgaga 4200 aatgtttttg gagttaaata ttttgattgt ttgaagggtt ggagtatgtt atgttatttt 4260 atagtttttt attttttaaa ttaaagttta gatttttgtt ttggattatg aattgaattt 4320 tatgtttttt ttttttgttt aatttaatat attttggtat aaataagtat aaagttagtt 4380 ttgggaagat tttgggtttg gaagagttga agtgttaaat attagttgtg g 4431 <210> 194 <211> 3357 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 194 tgaaatttaa atataaaatt tgttaataag gattaattgt atgtgtataa tttaaatttt 60 atttataaat ttaattatat tatttgattt tattagaatt aggttttatt ttatttttga 120 ttttgtttat tatttattta gtatttttgg taataggtgt ttgagtgttt ataggtggtt 180 tttgatttgt gaaagatttt gtggtgtttt tagttagggt ttagggttgg gtagtttagt 240 tagtttttag ttatggaggt tataggaagt agtagtagtt tgaaaggggg tggaagggat 300 gagggaaatt gaggttttag gaagggataa tattgtgttt taggttatat aaattattgg 360 tatttattag tgtttgttta agttttagga tttgttatag gtaattagtt tatatatgga 420 aaagaaattt tttatatttt tattttattt ttttttattt tgggtttagg atattattat 480 tttttaattt aaggattttt gttttttatt tttagtgttt taatttttta ttttttttta 540 tttttagatt gataatttat tatttttttt tattgttaat ttagaaattt tttatttttt 600 ttttttattt ttttttgtta ttgatttaag ggtttttatt tttttatttt attattttaa 660 gatttttata gtttttattt ttagttttaa agggttttat tttttttgtt tttattattt 720 gattttagta gttttttatt tttttttttt ttgatttagg agtttttaat tttttttttt 780 tagtgtttta attattttat tttttttttg tttgatgttt ttttattttg ttattttagt 840 gttataattt tgattttttt tgtgagatat aattgtttta atttatagtt tgaatagttt 900 tttatttttt ttatttttta tattggaagt tttttatgtt tttttttttt tagtttaaga 960 tttttttttt tatttttttt tttttttaat gtttttattt ataatttttt tttagtttga 1020 gtttttaaat ttttttttat agttaaaaag ttttttattt ttttttttta ttgtttttat 1080 tttttatttt ttttttatta tttagagaga ttttaatttt tttttttagt attttgaatt 1140 tttttttatt ttttttgttt ttgttttggg attatgttat ttttaattgt tattattttg 1200 attttttatt gttttttgtt ttttatatgg ggttttttat tttttttttt tagtatttta 1260 aagtttttat tttttttgtt attagtttga gggtttttta tttttttttt ttagagtttt 1320 gaatttttat ttttttttta attttagatg ttttgatgtt tttttttagt gttttgattt 1380 ttattatttt tttttgtttt tgttttagga ttttgatatt tttatttgtt agagtttaga 1440 gttgtatttt tttttgtttt tagtttaaat ttttttattt ttttttgtta gtattttgat 1500 gttgttattt ttttttttta ttggtttgag ggttttttat ttttttttgt tagtgttttg 1560 agttataatt tttttttatt ttttgtttga gtgtttttta tgtttagttt taaggttgtt 1620 ttattagttt ggtattaggt tggtattttt tgttatttta ggtttgtgga tttatggtga 1680 gggttttttt tgtatttttt gttttgtttt tttttttttt tttttttttt gtggttgttt 1740 tttttgaagt ggtagttgtt gtttttgtgg ttgtttgttg tttttggaat tggaagtttg 1800 ttgtttgttt tttgggtttt gtttttggtt aagtatttgt gtattattgt tttgatgttg 1860 tgtgttttta atagggaggt ttttgtgttt atgggttggt gttttgtagt ggtgtgtgtg 1920 tttttttgtt gagagttagt tgtatttgtg tgttgatgtt taatgatagt taattttttt 1980 gagggattgg tagttgtggt tttttttgtt gtttatttag ttggtgtatg tgttttttag 2040 ttttaatttg aagggaagtg gttggggagg gtttgtgttt gtgttttttt tttttttttg 2100 tggtttttat agttgatatt gaatgtggta aggaagttgt tttgtgtttg tgtatttttt 2160 ggttttgttg gtgttttttt tttttatttt ttgttggggt ttattttgtg tttgtgggtt 2220 tttttgaata ttaattttag ggggggttgt gttttgtttt tttttttttg ttgaatagtt 2280 gtgggagtgt gtggggtggg gaaaggggtg gtgttatatt gtaggtaaat tgaggtatgt 2340 gggagggtgt gtttttgtag gaggtggatt tttaatgtgg ggtttgtggg gaaaaggtgg 2400 ggtttggtgt ttatagtgga tgatagtttt gggtgggaga taggagtatg tatgggtggt 2460 gttattatat tgaaggtgtg ttgtgtagat tttttgtttg tgggaggttg ggaatgtggg 2520 tttttgggtt tttgtggggt gtaggtgttt tttattttat ttagaagttt ggaatagttg 2580 taattgtagt aatgtggaga tagttttttt ggttttttta aaattttatt aataaaattt 2640 agggagagga ggtaaggatg agtggatttt gtagttttat taggtattga atatgttgat 2700 ggggatagtt tttttgataa aggtagatgg gtggttaatt ggtggatggg tatagggaga 2760 attggagaaa tagatgagtg gaggaatgga tatatgggta ttgggtggtt tttttatttg 2820 gaatgtaggg tgtaaggggt ttgggttagg aggtttagtg gttggtattg gagtgtaggt 2880 tggtagtgag gggattgtgt tggattgttt ggtgtagtat tagggttagt aattttgtgt 2940 ggtttgttat ggttgtgtgt atattgtgtt tttgtttaaa tagtttgttt agtttgtatt 3000 attgttaagg gagtggtagg agttttaagt aggaatattt gtagttttgt ttgttttggt 3060 tatgtttgat atggaaattt attatatgta gtattaaaat tgtatagaaa tttattatat 3120 gtatgtgttt taagtttatt tttgtatgtt gtagtttttt ttagtagtaa tggtgattgt 3180 attggtgttt gggtaggtgg tagaagttat ttgtgagttt aaagatatta tgtataaggg 3240 ggtatttgta tattttgtta gttggtattt gtaaggaggt taggttgggg ggatgaatag 3300 tggtgataag ggagaatagg aatgggggtt taaggaggga gaaggaaaag aatggag 3357 <210> 195 <211> 3357 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 195 ttttattttt tttttttttt ttttttgagt ttttattttt attttttttt attattgtta 60 tttatttttt taatttggtt tttttgtagg tgttagttga tgaggtatgt gggtgttttt 120 ttgtatgtga tgtttttgag tttatgggtg atttttgttg tttgtttaag tgttagtgta 180 attgttatta ttgttgggag aagttgtggt gtgtggaagt ggatttggag tgtgtgtgtg 240 tggtaggttt ttgtgtggtt ttggtgttgt atgtggtagg tttttatgtt ggatgtggtt 300 ggggtaggtg gggttgtagg tgtttttgtt taggattttt gttgtttttt tggtagtggt 360 ataagttgga tgagttgttt gagtaggagt gtaatgtgtg tatagttatg ataaattgtg 420 tgggattgtt ggttttgatg ttgtattaga tgatttagta tgattttttt attattgatt 480 tgtgttttag tgttgattgt tgagtttttt ggtttggatt ttttatattt tgtattttag 540 atgggggagt tgtttggtgt ttgtgtgttt gtttttttat ttatttgttt ttttggtttt 600 ttttgtgttt atttattggt tgattgttta tttgttttta ttagagggat tgtttttgtt 660 gatatgttta gtgtttggtg gggttgtgga gtttatttat ttttgttttt tttttttggg 720 ttttgttaat aaaattttga agaaattaag gaagttgttt ttatattgtt gtggttgtaa 780 ttgttttaga tttttggata agatgggggg tgtttgtatt ttgtgagagt ttagggattt 840 atatttttag ttttttatgg gtagagggtt tatgtagtgt gtttttagtg tggtgatatt 900 gtttatgtat gtttttgttt tttatttaga gttgttgttt gttgtggatg ttaggttttg 960 tttttttttt ataagtttta tgttggggat ttgttttttg taggggtgtg tttttttgtg 1020 tgttttagtt tatttgtggt gtggtattgt tttttttttt gttttgtgtg tttttatagt 1080 tgtttggtgg ggaggaggga gtgggatatg attttttttg gggttgatgt ttggagggat 1140 ttatgaatat aggatagatt ttagtgagag gtgggagagg agagtgttgg tagggttagg 1200 gagtgtgtag gtgtgaagta gtttttttgt tgtgtttggt attggttgtg gagattgtgg 1260 gagggaaggg agggtgtagg tgtaagtttt ttttgattgt ttttttttag gttgaggttg 1320 gaaagtgtat gtgttagtta gatgggtagt gaggagagtt gtaattgtta gttttttgaa 1380 ggggttagtt gttgttgaat gttagtatgt agatgtaatt ggtttttggt aggggggtgt 1440 gtgtattgtt gtggagtgtt ggtttgtagg tgtgggagtt tttttattaa gggtatgtga 1500 tattgaggta atagtgtgta ggtgtttagt tagaggtgga gtttgagagg taggtagtgg 1560 atttttggtt ttgggagtaa tgaatagttg tggaggtgat agttattgtt ttagaggagg 1620 tggttgtgga ggaggaggaa ggggaggagg gtgaggtggg aggtgtagga gggatttttg 1680 ttatgggttt atgggtttag agtggtggaa gatattggtt tggtgttaaa ttggtgagat 1740 agttttgggg ttggatgtgg agagtgttta ggtggaggat gggaaggaat tgtggtttag 1800 aatgttgatg gggaggaatg aagggttttt aggttgataa gggggaggaa tggtggtgtt 1860 ggaatattga tgaggagaaa tggggggatt taggttgagg atgggaagga atgtagtttt 1920 gaattttgat aggtaggagt gttgggattt tgggatgagg atggagagga atggtggaga 1980 ttagaatgtt aaagggagat attggggtat ttgaagttga gagagaaatg ggggtttaga 2040 attttgagag ggagaaatga ggggttttta ggttgatgat aggagaaata gaggttttgg 2100 aatgttgaaa gggaggaata ggaggtttta tatagaggat gaggagtagt aggggattag 2160 aatggtgata gttagggatg gtatgatttt gggataagaa tagagagaat ggaggagggt 2220 ttggaatgtt gaggggagaa attagggttt ttttggatga taagggagga atggaggatg 2280 agaatagtaa ggaggagaag tggggaattt tttggttgta gaggaaggtt tgggagttta 2340 gattagggag aaattgtggg tgagaatatt gaaggagaag aaaaataagg ggggaggttt 2400 tgggttgagg aaggggaggt atgggaggtt tttagtgtga ggaatggaaa agatgagggg 2460 ttgtttaggt tatgggttgg agtagttgtg ttttgtagag gaagttgagg ttgtaatatt 2520 gaggtagtag gataagagga tattaggtag agaaggaatg gagtggttaa aatattgaag 2580 gagggaaatt aggaattttt gggttaagga aggggggaat gagagattat tgaagttaag 2640 tagtgagggt aagagaaatg gggttttttg gggttgagga tggggattat gggggttttg 2700 gggtgataaa atagagggat agaggttttt aggttagtga tagggaggaa tgagggggaa 2760 ggatgaaaag tttttggatt ggtagtgagg agaaatgatg ggttgttagt ttgaggatag 2820 agaggagtag gggattagga tattgagaat aagaaatagg gatttttggg ttgaggaatg 2880 atgatatttt aggtttagaa taggaaagaa tggggtgaga atatgagggg tttttttttt 2940 atatatgggt tggttgtttg tggtaggttt tagggtttgg gtaagtatta atggatatta 3000 gtgatttgtg tggtttgggg tatagtgttg ttttttttta gagttttagt tttttttatt 3060 ttttttattt ttttttaggt tattgttgtt ttttgtggtt tttatggttg aggattggtt 3120 ggattgtttg gttttgggtt ttggttggaa gtgttgtgaa gttttttgta agttaggggt 3180 tatttgtgga tgtttagata tttattatta gaggtattgg gtgggtagtg ggtagagtta 3240 ggagtggggt agagtttgat tttggtaaaa ttaaatggtg tggttaaatt tatggatgaa 3300 gtttaaatta tgtatatata gttaattttt attagtggat tttatgtttg aatttta 3357 <210> 196 <211> 2170 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 196 gtgatttttt tttttaggat ttagtagtat tttattgtgt tatagtagtt agtattttta 60 aagtatatat tttaatattt tttggttgta gtatatttaa tttttttgtt ggggtgtggg 120 ggtttttttt tttttgagta tagtttttgg ttttttgatt ttttttgttt tatttttttg 180 ttttttaagt atattgtgtt tattttttta ggtagttttt ttagtggttg ggtagtagta 240 gggttttgag tttgtttttt ttggggtggt tatatgtgtt tattttttgg ggttggggat 300 tgtttttttt gtttggttgt tgattggtgt ttttttttat tttatttttt ttgttgtttt 360 ttagttttta ttttattttg ttttagttta attagtttta ttgttttttt tttttggaga 420 aaaaagttat tttagagttt tttgggtgtt gtttttggtt ggaataaaag tgttaagaaa 480 taggtggaaa gtattttatt tttttaggtt ttatattttt agggtggata gtttgttttt 540 gttttggttt tgtttttggt attaataata attgaatttt tatatgtgta tgtttttgtt 600 tttagtttga ttgaaaggat tattttgtgg gttttttaaa aggatgtgat tatttaggtt 660 aagtgggggt gggagagttt ttggttgttt ttttttggga aagtgtttta attttttagt 720 tttaaagttt tggagggtgg agggtgtttt gtgagagttt ttgggggtgt ggtttgtgtt 780 ttttgggttt tgtggatttg ggtttggggg tgtgtgtttt gttttttttt ttttttggtg 840 gtgtagttgt ttgggtgggg gtggggtggg ggttggggtt tgtgtgggat taattaggat 900 tggggtggga gttgattgtg gttggtgggg agggttagtt ttgttttggt gggtgggtgt 960 gtggtagggg tttttggagg ttttgagttt ttgggaggtg ttttggttaa ttttgggttg 1020 gtggggattg ggtttgggtg tggggttttg aaggtgtgga aggaaagttt gggattttgt 1080 tattttttta tagtgttttt ttttttgtaa tatttagttt ttttattgtg gggtttggga 1140 gtttttggag ttgattttgt tattattatt tttttgggtg agtgtggagg atgggttggt 1200 tattttggtt aggttggagg tgttttttag tttggggttt tgtgataatt gggttgaaat 1260 ttgagggttt tggagtgtgg tgggtggtgg gagtttgtgg agtgtggtgt atttggtggt 1320 taggtattgg ttagtttagt ggtagttttt ttttttttat ttttattttt atttttggaa 1380 ggagttgaga attagttgat tggttggtag gttgaattgt tttttttttt atggtaatat 1440 gtgttgtgat tttttatttt ttgtttttgg ataaaggtga atggtaattg tgttggttag 1500 tttttgtttt ttgttttgtg gatgggtttg ttgatgtagt aattaaaatt agagttattt 1560 ttttggaaga gtaaattgtt gttgttgttt ttttagtttt atggatttta ttttgtgtta 1620 tttttgggtt gattttaatt tgtttatttt agagtttttt gttttatttt tatttttaga 1680 tttagttgtg tttgttgaaa tattagttgt tttttttgtg aatgaagtgt gggaatttgt 1740 ttttgttgta gttaatgaaa ttaggaaaat aaaaagatta aaagggttgg ggatgggaga 1800 atgaagagga atgtagatag atagtttagg gttatttatt ggtttttggt gatttttagt 1860 tttttaagtt gattaaaata atgtgaggaa atgtgggttt ttttattttt taggaagagg 1920 taataatggg tattttatgt ggtgttatag tgtttgtttt taaagtttga atgtgaatgt 1980 agtaagtata attttattaa tgaaaatatt ttttagataa ttgttaatat tgatgaaaga 2040 agagaaatag agatatggaa gttaaagagt tgggaatttt aaaggttaaa ggatgttttt 2100 tagttatttt gatgttttgt gttttttttt agttggtata aaattgtgag tagtttaatt 2160 atattttgta 2170 <210> 197 <211> 2170 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 197 tgtaggatat aattaaatta tttatgattt tgtattaatt gaaagaaaat ataggatatt 60 agagtaattg agaaatattt tttgattttt aggattttta attttttagt ttttgtgttt 120 ttgttttttt ttttttgtta atattaatag ttgtttaaag aatattttta ttaataaaat 180 tatgtttgtt atatttatgt ttaaattttg aaaataaatg ttgtggtgtt atgtaaaatg 240 tttgttatta ttttttttta aaaagtggag aagtttatat ttttttatat tgttttaatt 300 agtttaagga attaagaatt gttaaaagtt agtgagtggt tttagattat ttgtttatat 360 ttttttttat ttttttattt ttaatttttt tgattttttt atttttttga ttttattaat 420 tgtgatgaga gtaagttttt atattttatt tatagaagaa gtaattgata ttttagtaaa 480 tatgattaaa tttaaaaata aaggtgaggt aaagagtttt gaaataaatg agttaaaatt 540 aatttgaaaa tggtataaag taagatttgt ggggttgggg aggtaataat aatgatttgt 600 ttttttaaaa gagtggtttt aattttgatt attgtgttgg tgaatttatt tgtagaatag 660 aaaataaaaa ttgattaatg tagttgttat ttatttttgt ttaaaggtaa aaggtgaaaa 720 gttatgatat atattgttat agaagagaag gtaatttaat ttgttaatta attgattaat 780 ttttagtttt ttttaaaaat aaaaataaaa ataggagaaa gggggttgtt gttgggttgg 840 ttgatgtttg gttgttgagt gtgttgtgtt ttgtaagttt ttgttatttg ttgtgtttta 900 ggatttttgg gttttggttt agttattata aagttttggg ttggaaaata tttttggttt 960 ggttagaatg gttagtttgt tttttgtgtt tgtttggggg gataatggtg gtgagattaa 1020 ttttaagggt ttttgagttt tgtgataaag aggttggata ttatgggagg aaggatgttg 1080 tggaagaata atggagtttt aaattttttt tttatatttt tagagttttg tgtttaggtt 1140 tggtttttat tggtttgaag ttggttggag tgttttttgg gagtttgggg tttttgggag 1200 tttttgttat gtgtttgttt gttagagtgg ggttagtttt ttttgttggt tgtggttgat 1260 ttttgttttg gttttagtta attttatgtg ggttttggtt tttgttttat ttttgtttgg 1320 atagttgtat tgttagggag ggggaggggt ggggtgtgtg tttttgggtt tagatttgta 1380 ggatttaggg ggtgtgggtt gtatttttga gaatttttat gaggtgtttt ttgtttttta 1440 ggattttggg attggggagt tgaagtattt ttttaaggga ggatggttag gagttttttt 1500 atttttattt ggtttgagtg gttgtgtttt tttaaagggt ttgtggggtg gtttttttgg 1560 ttgggttaga gatagaaatg tgtatgtgtg ggagtttagt tattattgat gttgagggta 1620 gagttggagt aggagtgggt tgtttatttt agaaatatga agtttagaga agtgaagtgt 1680 tttttatttg ttttttaatg tttttatttt agttgagaat ggtgtttaag gagttttgaa 1740 gtggtttttt tttttgaggg aagaaggtgg tggggttgat tgagttggaa tgaagtagga 1800 tggaggttgg agagtggtgg gaagggtggg gtagggggag gtattaatta gtagttaagt 1860 gggaagagtg atttttaatt ttagggaatg gatatgtgtg attgttttgg agaagatggg 1920 tttggaattt tgttattgtt tggttgttga aagagttgtt tggaagagtg agtataatgt 1980 gtttggaagg tggggggatg gggtagagga aattgggaag ttggggattg tgtttggagg 2040 ggaggagatt tttatgtttt ggtggaggga ttgaatgtgt tatggttgaa gggtgttgga 2100 gtgtgtgttt tagaaatgtt aattgttgta gtgtggtgga gtattgttaa attttaagaa 2160 aaaaaattat 2170 <210> 198 <211> 2251 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 198 ggattttgag ttgtttttag gtagttagga gtggttttag tggtagttgt aaattttagt 60 agttgtttgt gttgtttgtg gttggggtgg agggtagtta gagttgggga ttaaggtttt 120 gtgttatttg tgtgtatagt tttatatttg aatgttgttt ttttgtagat gagattggtg 180 ggtattgtaa agttgggatt tgtttttgaa ggaaaaaaaa tagtgagtaa gaaatttagt 240 attatttttt attgatttat tttgttgtat tttttgtttt ttaagttttt gaaagttggt 300 aattttgatt ttggtgttta aaaattgata gttattgaga ttggttttga gaagttgaag 360 atttggtagt ttttagattg agtaggataa ggtgaaagta ggttggaggt gggtttagga 420 tatttgaggg ttgattttgg gggtttgtga ggttgttatt gttgttgttg ttataggtga 480 gatggtgttg ggttgatgtt ggggttaatg ggtagagaat gtagggatgt ggtttttgtt 540 gaagagagtt aagaagggaa gagtgtgttt tttaaattgt ttttgtaatt tgtttttagt 600 gagtatttta ttgatttaga atttattgag aatagtatta gtgagttatt ttttttttga 660 gatgggtttt atttattttg gtaatggagt gagttggatt gtggggagga agaggaatgg 720 gaaaattagt ttataaatat taatgttagt aagagtgtgt tgttggtagg atgtattgtg 780 agtttggaga ttttggtggt tgtagttggt aagtggttat aatttagaaa gtaggattga 840 gttgtttttt ttgttttatt agtgtattgt tttttgggtg tgggtttaat attttataag 900 tggtaatttt tgtttatggt agttttgttt tttttttatt atttttagat ttagttttgt 960 attttaaggt tgtgtattgt tagttattat tatgtttatt tttggggtta atttgtttgt 1020 ttttttgagt tttgattggt tgaatagttt agtgattatt ttggtggtga tgtttatttt 1080 tggggtggtg ggtaatttgg tggttattgt ggtgttgtgt aagttgtgta aggagtagaa 1140 ggagatgatt ttttatatgt tggtatgtgg gttggttgtt attgatttgt tgggtatttt 1200 gttggtgagt ttggtgatta ttgttatgta tatgaagggt taatggtttg ggggttagtt 1260 gttgtgtgag tatagtattt ttattttgtt tttttttagt ttgtttggtt ttagtattat 1320 ttgtgttatg agtgttgagt gttatttggt tattaattat gtttattttt atagttatta 1380 tgtggataag tgattggtgg gttttatgtt ttttgtagtt tatgtgttta atgtgttttt 1440 ttgtgtgttg tttaatatgg gttttggtag tttgtggttg tagtatttag atatttggtg 1500 ttttattgat tggattatta atgtgatggt gtatgttgtt tatttttata tgtatgtggg 1560 ttttagtttt ttttttattt ttgttattgt tttttgtaat gtgtttgtgt gtggtgtgtt 1620 gttttgtatg tattgttagt ttatgtgttg tattttgttg ggtattgagt agtattatgt 1680 ggttgtggtt gttttggttg ttttttgggg ttattttgtt gtttttttag ttttgttgtg 1740 ttttagtgat ttttggtgtt gttggagttt ttgttgtatt gtgggtgttg agatttagat 1800 ggttatttta tttattgtta tttttttggt ggtgtttatt tgttttattt tgtttgtggt 1860 gagtgattgg ggttggggtt ttatttggtt ttttttttgt atttattttt tgtgtttatt 1920 ttttgttttt tgtttttttt ttgagttttt ggtagtgaat gtgttgtttt taggttgggg 1980 ttgggatttt tatattgttt tttagagtag gtttaatttt ttttgaagtt ttaattttaa 2040 tgagatttag taggtgtttt gtttttatat tttttagttt atgtttttgg aagtttgggt 2100 tttttttttt attgagatag tttttatttt ttgttgtttg atattggttg agttttttaa 2160 gaaaattttt tgtttttttt gttagatgtg gaggggagtt tgttgtagtg tgatttagtt 2220 tatttttttg tattgtgaat tgtgaattgt a 2251 <210> 199 <211> 2251 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 199 tgtagtttat agtttatagt atggaggaat gggttaagtt atattatagt aggttttttt 60 ttatgtttaa tagagggggt ggggggtttt tttggaagat ttggttagtg ttaggtagta 120 aggggtaagg gttgttttgg tggagaaaga aatttaggtt tttgggaata taaattgggg 180 gatgtagggg taaagtattt gttaaatttt gttagggttg ggattttaaa gagggttggg 240 tttgttttga gaaatagtgt gggaatttta gttttgattt aaaggtgata tgtttattgt 300 taaggattta gagggaaagt agggagtggg gaatggatgt gggaggtgga tgtgagaaaa 360 aggttgagta gggttttagt tttggttatt tattatgagt gggatggagt agatgagtat 420 tattagggag gtggtaatga gtaagatgat tatttggatt ttggtgtttg tgatgtggtg 480 gaagttttgg tggtgttgaa agttgttgag gtgtggtaag gttggggagg tagtggggtg 540 gttttgggag gtaattgagg tggttgtggt tgtgtggtgt tgtttggtgt ttagtgaggt 600 gtggtgtatg aattggtggt gtatgtggag tagtgtgttg tatataagta tgttgtagag 660 gatggtggtg agaatgagga aggagttgaa gtttgtgtat atgtaggagt aggtggtgtg 720 tgttgttatg ttggtggttt agttgatgaa gtattaggtg tttgggtatt gtagttgtga 780 gttattgaga tttatgttgg gtagtgtgta aaagagtatg ttggatgtat agattgtaaa 840 gagtgtgagg tttgttaatt gtttgtttat gtagtggttg tagaaatagg tatggttgat 900 ggttaggtag tgtttgatat ttatggtgta gatgatgttg aggttggata ggttgaagaa 960 gagtagaatg aaggtgttgt atttgtatag tggttggttt ttgggttatt ggttttttat 1020 gtatgtggtg atggttattg ggtttattaa taaagtgttt aataggttgg tgatagttag 1080 tttatatatt agtgtgtaga aggttgtttt tttttgtttt ttgtgtgatt tgtatagtat 1140 tatgatggtt attaggttgt ttattatttt gaagatgaat attattgttg ggatggttat 1200 tgggttgttt agttggttgg ggtttaagga ggtggatgaa ttgattttgg gagtggatat 1260 gatagtggtt ggtggtgtgt agttttggag tgtaaggttg ggtttgggga tggtagaaga 1320 gagataaagt tgttgtgagt ggaaattatt atttgtaagg tgttagattt gtgtttgaga 1380 aatgatatat tgataagata aggggagtaa tttgatttta ttttttggat tgtagttatt 1440 tattaattgt ggttattaaa atttttaggt ttgtgatatg ttttgttaat agtatatttt 1500 tgttgatatt aatatttata aattgatttt tttatttttt ttttttttta taatttaatt 1560 tattttattg ttaagatgaa taagatttat tttaagggaa aagtagtttg ttagtgttat 1620 ttttgataga ttttgaatta ataaaatgtt tattgaaaat aagttataaa agtaatttgg 1680 agagtgtgtt tttttttttt tggttttttt tggtgagggt tgtatttttg tgttttttat 1740 ttgttgattt taatgttagt ttaatgttat tttatttgta gtggtagtag tggtggtagt 1800 tttatgagtt tttagggtta gtttttagat gttttggatt tgtttttaat ttgtttttat 1860 tttgttttgt ttagtttgga aattgttaaa tttttggttt tttaaagttg gttttagtgg 1920 ttgttgattt ttggatattg aggttagagt tgttagtttt taaaaatttg ggaaataaga 1980 ggtgtagtgg gatgggttag tgaagaatgg tgttggattt tttatttgtt attttttttt 2040 ttttaaagat gagttttagt tttgtagtgt ttgttggttt tgtttgtggg aggatagtgt 2100 ttaggtgtga ggttgtgtgt gtaggtggtg tggagttttg gtttttagtt ttggttgttt 2160 tttgttttag ttatgggtag tatgggtggt tattggagtt tgtggttgtt gttgaggttg 2220 tttttggtta tttgggggtg gtttggggtt t 2251 <210> 200 <211> 2297 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 200 agaaaaatat tattgtgttt ttttgtttgt atttaatata tttaaggttt tttatttatt 60 tttttggaat aaatttttag taaatattta tttattgatt tgggagtgat ggatttttat 120 aaaggtttga ttgtttttta agtggttgaa gtgatttgtt tttgtggttt ttttagtatt 180 gaagggggtg ggggaagtgg atttgagggg gtgtatgttt ttgttgttgg tgggtttatt 240 ttttaaaaat tattgagatg tgttagggtg gttgtgatta agtgggttta gggttaattg 300 tgtgaggggg aagtgttttt tagagtgtgt gtagtgttgg gggtttagtt tatgttgttg 360 tgtgtttttg tgtgtattgg gtgaggatgt tgagttttgt gggtattttg gaagttgtgg 420 tggaggtagg ggttttgttt ggtgtagtgg gtttgttggg gaggtgtagg ggaggttttg 480 atttttggtt tatttttttt tagatttttt tgtttgtttt tggattttta gggttttttt 540 ttaaattttt ttttgttttt tttatgggag gtttttgtag tttttgggtt ttagggtttt 600 gtaagttttg ggattgattt gtgtttgggg tgggtgtggt ggaagtttga attggattat 660 ttaggtatgt tatttgtaga tgtagtgggt gagggggatt ttgttatttt tttagttttt 720 tttttggatt ttgtagtgag gggaattaaa ttttttttat gatagttttt ttggtgttag 780 tttggattga gtggttatag gttggattag ggtaggtaga agatgtattt ggtattttat 840 tgaatggtat ttgaatttgt ttttattatt tattaatggt gtgattttag gtaatttatt 900 taaatttttt gaattttagt ggtttttatt tataatatgg gggttaatga taatgttttt 960 tttgtatgta ggtggattaa atggatataa agtgtttatt tttgtttggt atgtttaaaa 1020 tttttattaa taggttagtt aattttatta tgagaggaat tttttttttt ttgtttttta 1080 gagtgtgggt ggtatgaggt tatggaagta gttgttgtaa ttagtatttt aaaatttaga 1140 gattttttaa tggtggtagg gggtgaaagg gtagggggga ggtagggttg ggataggtag 1200 aggtaggttt ttggggattt ttagttttgg ggattaagtg tttggaatta gttgggtttg 1260 ggtagaaata agaaggtaaa tgatgggatt gttgttggag tttggatttt tatttttgga 1320 gtttattgtt ttttttaggg aatagaggag tgttttggtt ttttagtaat gaattaggag 1380 agtgtgagaa agagtatttg tttttttttt tgtggtttga taagttattt tttggtagtt 1440 ttgtgagtag attaattgaa atgggtttgg aattttattt tttttttttg atggagttgt 1500 tggaggtttg tggatattgt ttggttagtt tttgggatta tagtgttgtg ggtttttttt 1560 tgtggtgttt gttttaaatt tgggtgttat taatttattt aataatgatg gatgattttg 1620 ttataatgat gttagttaaa atatttttgg tttaattttt ttttaattaa tattgaagta 1680 ttttgaatga gatttggatg aagtttgaat agtatgtttt ttaggtttag aaaatttgag 1740 tggtgggaag agaaaaagaa ataagtagaa attaggaaag aatggttatt aattgtttag 1800 attggtaagt gttaaataag ttaggttgtt tggaaaaaga taaatgttgt tttttttttt 1860 tatggtatgg ttagaatttt ggtgatggga aagtattttt tgagttggtt aattttatat 1920 attttgtttg tgttttttat tatttattat tgaaaatgtt aggaagagtt ggggggtaag 1980 tgtttttttt gtgggtgtga gattgtattg aagggttgtt ttggtataaa gtttggggag 2040 aggatatggt ggaggtgggg ttgtattttt attttgtttt tttaatatta ggttttgggt 2100 agagaaattt atgtgtgatt ttttgtggta gttgtaggta gttgattgta aatagttttg 2160 tttgtgtttt ggagtagttg tgttattaga tgtaatattg gatatttgtt tttgggtttt 2220 aagaaggaga gggaaagagt tttttagaag ataatttgag aaggggttag tagagtgttg 2280 ggtggagtgt agatttt 2297 <210> 201 <211> 2297 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 201 ggagtttgta ttttatttag tgttttgttg attttttttt gggttgtttt ttggagggtt 60 tttttttttt tttttttggg gtttggagat aagtatttag tgttatgttt ggtggtataa 120 ttgttttggg atatgggtga ggttgtttgt ggttagttgt ttgtggttgt tgtaggaggt 180 tatgtatagg tttttttatt taaaatttgg tgttagaggg gtagggtggg agtgtagttt 240 tatttttatt atgttttttt tttagatttt gtgttagggt agttttttga tgtagttttg 300 tatttatgaa ggaggtattt gttttttagt tttttttggt atttttggta gtagatggta 360 gagggtatag gtagggtgtg tgaaattgat tgatttagga ggtatttttt tattgttggg 420 gttttggtta tattgtaaag agaagaaatg gtatttattt ttttttaaat aatttaattt 480 atttagtatt tgttaatttg agtaattaat agttattttt ttttgatttt tgtttgtttt 540 tttttttttt tttattattt aagttttttg aatttgggaa atgtgttgtt tagattttat 600 ttgggtttta tttaggatgt tttgatgttg gttggaagag agttagattg aaaatgtttt 660 gattggtgtt gttatgataa ggttatttgt tattgttgga tagattgata gtatttaagt 720 ttaaggtaga tattatgagg gaaagtttat ggtgttgtgg ttttggaggt taattaggta 780 gtgtttgtag atttttagta attttattgg gaggagagga tgaagtttta ggtttgtttt 840 aattaatttg tttgtagaat tgttgaagag tggtttgttg ggttatggga gaagaaataa 900 atgttttttt ttatattttt ttggtttatt gttgagaaat taggatattt ttttgttttt 960 tgggagagat agtgaatttt agggatggaa gtttggattt tggtggtggt tttgttattt 1020 gtttttttgt ttttgtttaa atttagttag ttttaagtgt ttggttttta agattggaag 1080 tttttaagaa tttattttta tttgttttaa ttttgttttt tttttatttt tttatttttt 1140 gttattatta gaaagttttt ggattttgaa atgttagttg tagtagttgt ttttgtggtt 1200 ttatgttgtt tatattttgg gaagtggagg agggagggtt ttttttgtaa taagattagt 1260 tgatttgtta atgagagttt tggatgtgtt gggtgggggt aggtgtttta tgtttattta 1320 atttatttat atgtggagaa ggtattatta ttaattttta tattgtagat ggggattgtt 1380 gaggtttgga aagtttagat gggttgttta aggttatgtt attaatgagt aatggagatg 1440 gatttaaata ttgtttggta aggtgttaag tgtatttttt gtttatttta gtttaatttg 1500 tagttatttg gtttagattg atgttagagg ggttattatg ggagagattt ggtttttttt 1560 gttgtggggt ttagggaaga agttgagaag gtagtaaagt tttttttgtt tattatgttt 1620 ataggtggtg tatttgggta atttgattta agtttttgtt atatttattt tgggtataag 1680 ttgattttga ggtttatggg attttaaggt ttagaggtta taggaatttt ttgtgaaggg 1740 ggtaggagaa agtttgaggg agagttttga aggtttggga gtgaatgaaa aagtttggaa 1800 gggaatagat taggagttag gatttttttt gtattttttt agtaggttta ttgtgttgag 1860 tggggttttt gtttttattg tggtttttgg gatgtttgta gagtttggta tttttatttg 1920 gtgtgtataa gggtgtgtag tggtgtaagt tggatttttg atgttgtgtg tgttttgagg 1980 ggtgtttttt ttttatatag ttgattttgg gtttgtttgg ttatggttat tttggtgtat 2040 tttaatagtt tttagaaagt gagtttattg atggtaagga tatgtatttt tttaaatttg 2100 ttttttttat tttttttaat attgagaaga ttatggaaat aaattatttt gattatttag 2160 aaagtgatta aatttttata aaaatttatt gtttttaaat tgatgggtga atatttgttg 2220 ggaatttgtt ttagaggaat aaatgaggag ttttgagtgt attaaatgta aatgggggga 2280 tatggtggtg ttttttt 2297 <210> 202 <211> 2590 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 202 gtgttgagta ggtgtggtta tggtgtttag attttttggg ggtattttag tttttgttat 60 ttagtggttt atggttgtgg gttttagggt ttgaggttgg ggattattgt tgttgttgta 120 gtttttatat tttgaagttg ttttgttgtt tgtgttgttt ttgtagatag tatttttggt 180 gttttgtgtg tttttttttt tttttttttt tttttatttg tttttattgt tttgagtttt 240 tgaaagttgg gagaattgga gatatttttg aggattggta atgaagtttt atttaagtgg 300 gatgtaattt ttgttttttt attttttttt aagaaggagg ttgtgttttt attttgtttt 360 gttttgggtg ttgattttta aaaaattaga gtaaaatgaa tgtgaataaa aagaaaagga 420 gaaatgtttt gagttggggt agagggagta gagaaggagt ttttattgtg gttggaatgt 480 agagtggatt ttggtttagg attgggtttt tttttaggtt tgggtttatt ttggtttttg 540 ttgttggaat ttttaggagg taaagtgatt ttgatttttg ttgtttgtat ttttgggtgt 600 gagtgttttt tttaggaggt ttaggaggtt gtttttgttg tattttgagt ttttgttgta 660 aaaattgaag tttgtgggtt ttggtaggtt ttttagtttg tttgttttgg gataggtttt 720 tgtttatatt tttggaagta aggagttttg ggtttttttg ttttttttgg ggtgtggagt 780 ttttggggtt tttgaaaggt gaggttttag aggtgaggga ggggtgagtg gggagttttg 840 tttgtttgtg gttgtgtttt tgttgtggat taggaggtag gttaattttt tggattttgg 900 gggaaaaatt atagtgggtt ttttgtggaa attttggttg ttttaatttg ttaagagttt 960 gagtgaggtt ttggaagttt ttagttttgg tttaggttgg gatgtggttg ttgagttttt 1020 ttaggtttgt aggatagtgg tttttgttgg tggtgttgtt gtatttaggt tttttttaga 1080 ttggtggtgg tagttaattt gagatttgtg ttttttgggt ttggggtagt taggaggttg 1140 gtgtgtagtg ggttgggtta ggattgggtt gagtagatag agttgtagtt tttgttttgt 1200 ttggtttttt gtggttggag agtagagtga tgttatttgg agttttgttt gggtggtaat 1260 gagattttgg ttagttattt ttgtagttta gattaatttt ttttaatagt ttttgatggt 1320 aattatagta attgaagttg ttatatattt ttaggtaatt atgatatata aaaagttttg 1380 aggggatttt ttggtgaggg aagttaagaa tggtttttta gttttaggaa attttggttt 1440 gttttatgtt ggagtttgtt tggtttgtta aatgagagga gttttgtaat ggggttaatt 1500 agtttgtttt gtgattttaa gttattttaa tgtggttggg tggtggagtt tgaggtatag 1560 gtttgttatg ttttggaatt tttgtgtttt ttttttttgg gttttgtttt agtttggttg 1620 tttgttttta atttgttttg ggagttgtgg tttagaggtt tgtttagagg taggatttgt 1680 attggtggtg gtttagaggg taatagtttg gaagtttggg tgggggaatt tgaggagggg 1740 tttttatttt gtattggttt tttttttatt tttattgggt tttttagaga tgttgttatg 1800 ggttttttgt ttggatggga agtggggaaa aagagatttt attattgttt tttttattta 1860 tttattttgg tatttttaat agtgttatag ggaagaggat agttggggtg atagtattgt 1920 tgggttttaa atgtggattt tggagtggtt agagggtgtg tgttaagtag aggatggttg 1980 taagatatgg aaattaagtt tattgttttt agagtgagtg tagtgtagtg gagttttaga 2040 tttggttttt gagtgattag gaattttttt gggtgtagtg ataggtttga aggagtggag 2100 gataagattt gttgtgtttt tgtttggttt tttttagttt ttttttttta tagtataatt 2160 tttttttttg ttttgtggga ggggggtgtt gagttggtgg ttgttgtgtt gtgtgttttt 2220 tttgtttgtt tttgttgttg tttgaatttt tatgttattt tttttgatgg gttattggtg 2280 gttttatagg taggtgttgt tgtggggttg taattatttg gttgagtttg gttgttattg 2340 aatatttttt tatttttaag tatggttttt tgtgtttttt tttttttatt ttttttattt 2400 gagatgagtt tgggatttat ggtgtaagtt tgtttggatg ttttgggttt taggagtaag 2460 tttatatttg tggtgttttg aggttttttt tgtgttatgt ttttattttt tttatttttt 2520 ttgtttagat gttttattgt tgtttttttt tattttaatt ttattgtagt ttttaattta 2580 agtgtttttg 2590 <210> 203 <211> 2590 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 203 tgaaagtgtt tgggttgggg attatgatgg gattgaggtg ggaaggggtg gtagtggaat 60 gtttgggtga ggggagtagg ggaggtgagg gtgtggtgtg gggagggttt tgaggtattg 120 taggtgtaaa tttgtttttg gaatttgagg tgtttgggtg agtttgtatt gtgggtttta 180 gatttgtttt aggtggaggg ggtgggggaa ggagagtgtg ggggattgtg tttgggggtg 240 agggggtgtt tggtaatgat taggtttggt tgggtaatta taattttgtg gtagtatttg 300 tttatagagt tattagtgat ttgttaaaaa gagtagtatg ggaatttgga tggtgataaa 360 ggtgggtagg ggaggtgtgt ggtgtggtgg ttattggttt ggtgtttttt ttttataggg 420 tgggagggga gattgtgttg tgggagggag gggttggaga gggttaggta agggtatagt 480 gggttttgtt ttttattttt ttgggtttgt tattgtgttt aagggagttt ttggttgttt 540 aggaattggg tttggagttt tgttgtattg tatttatttt ggaagtggta aatttggttt 600 ttatatttta taattatttt ttgtttaata tgtgtttttt gattgtttta gggtttatgt 660 ttggggttta gtagtattgt tattttagtt gttttttttt ttgtggtatt gttgaagatg 720 ttaagatgag tgagtgggag gagtagtggt ggggtttttt tttttttatt ttttatttgg 780 ataggaggtt tatgataata tttttggaga atttgatgag ggtggaggga agattagtgt 840 agggtggggg tttttttttg gatttttttg tttgagtttt tggattgttg ttttttaggt 900 tattattagt gtgagttttg tttttgagta gatttttgag ttgtggtttt tggggtagat 960 tagaaatagg taattgggtt ggggtggggt ttaggaggga gggatgtgaa aattttgggg 1020 tatagtgggt ttgtgtttta gattttgtta tttagttatg ttaaggtgat ttggggttat 1080 gagataagtt ggttgatttt gttgtaaagt tttttttatt tagtaagttg agtgagtttt 1140 gatgtgaggt gagttggagt tttttgaagt tggaaaattg tttttaattt tttttgttag 1200 ggggtttttt tggggttttt tgtgtgttat aattgtttaa agatatatgg tagttttgat 1260 tattgtaatt attattagag gttgttgaaa gaagttagtt tgggttgtag gggtgattgg 1320 ttagggtttt gttattattt aggtggggtt ttgggtgata ttgttttgtt ttttagttgt 1380 gagaagttgg gtaaggtggg ggttgtagtt ttgtttgttt gatttagttt tgatttggtt 1440 tgttgtgtgt tgatttttta gttgttttgg gtttgaggga tgtaagtttt gggttggttg 1500 ttgttattgg tttggaaagg gtttaaatgt agtggtgtta ttggtggggg ttgttgtttt 1560 gtgggtttga gaaagtttag tagttgtgtt ttgatttgag ttggggttgg aggtttttaa 1620 ggttttattt aggtttttgg taagttagaa tggttaaagt ttttgtaagg agtttgttgt 1680 ggtttttttt ttaaagtttg gagggttggt ttgtttttta gtttatagtg ggggtgtagt 1740 tgtaggtggg tagagttttt tgtttatttt ttttttgttt ttgaggtttt attttttaag 1800 ggttttaggg gttttatatt ttgaaaagga tgaaagagtt tggggttttt tatttttagg 1860 ggtgtaggtg agggtttgtt ttggggtgag tgagttagga ggtttgttga gatttatggg 1920 ttttagtttt tgtaatggag gtttagaatg taatagaaat ggttttttga gttttttggg 1980 aaggatattt atgtttggga atgtgggtaa taaaaattga ggttgtttta ttttttggag 2040 attttaatag tgagggttag ggtaggtttg agtttaaagg gaaatttagt tttgggttag 2100 ggtttgtttt gtattttggt tgtggtgagg gttttttttt tgtttttttt gttttagttt 2160 gaaatatttt tttttttttt tttgtttatg tttattttgt tttaattttt taaaggttag 2220 tatttaaagt aaaataaaat gaaaatataa tttttttttt ggaggggggt aggagggtgg 2280 gaattgtatt ttatttaagt gagattttat tattagtttt tagaagtatt tttgattttt 2340 ttaattttta aagatttagg ataatgaggg tgagtgaaag ggggaggggg agggaaggaa 2400 tgtatagagt gttaaaaatg ttatttgtga aaataatata agtagtaagg taattttggg 2460 atatggggat tgtggtggta atggtagttt ttagttttag attttggagt ttgtagttgt 2520 gggttattgg atggtgggaa ttgaaatgtt tttgggagat ttgagtattg tgattgtgtt 2580 tgtttaatgt 2590 <210> 204 <211> 17 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 204 ggtgggtggt tagtgaa 17 <210> 205 <211> 28 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 205 ttattataac aataatacct aaaaaaaa 28 <210> 206 <211> 21 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 206 ggtgagtaag cgtttacgtc g 21 <210> 207 <211> 15 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 207 cgagcgtcgg ggagg 15 <210> 208 <211> 39 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 208 aaaacacatc aaaaccacaa aatttacaaa aacacaaca 39 <210> 209 <211> 28 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 209 tttagtatgt ttttaattag agtgttaa 28 <210> 210 <211> 22 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 210 cctaacaaac ttaactactc cc 22 <210> 211 <211> 17 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 211 cgggatttag gcggtcg 17 <210> 212 <211> 23 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 212 attttcggag gttttcgatt agg 23 <210> 213 <211> 25 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 213 ctcccaaacc ctcattccaa cccca 25 <210> 214 <211> 14 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 214 ccccaaaccc tccc 14 <210> 215 <211> 23 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 215 tttgtttagg aatttgtagt tgt 23 <210> 216 <211> 18 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 216 cgggttagga agttcgcg 18 <210> 217 <211> 20 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 217 gacgtcgcga ttgttttttg 20 <210> 218 <211> 26 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 218 ccccaccaca aacacctaac ctcccc 26 <210> 219 <211> 17 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 219 ccctctacct ccctact 17 <210> 220 <211> 16 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 220 ggagagaata gggggt 16 <210> 221 <211> 15 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 221 ggtggggcgt cgtcg 15 <210> 222 <211> 20 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 222 cgttacggtt tttggtgtcg 20 <210> 223 <211> 40 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 223 caaactaaac ctatcaaaaa tcttttacaa tcaacaaccc 40 <210> 224 <211> 27 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 224 ctaaaccaaa taaaaaaaaa taaaaac 27 <210> 225 <211> 22 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 225 gatgggtagg tatagatttt ag 22 <210> 226 <211> 24 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 226 ggattttttt cgaagcgttt tttt 24 <210> 227 <211> 22 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 227 taagagcgcg ttttttatcg aa 22 <210> 228 <211> 34 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 228 aaataaaaac acactaaaca caccaccata cact 34 <210> 229 <211> 23 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 229 ttttgagtga gtttttaaat ttt 23 <210> 230 <211> 18 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 230 cctcctccct ccactaac 18 <210> 231 <211> 20 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 231 tcgttttttt ggaatgggcg 20 <210> 232 <211> 21 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 232 acgcgaggta cggattttag g 21 <210> 233 <211> 28 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 233 taaccacctt tctccatcca acatccca 28 <210> 234 <211> 17 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 234 agtggaggga aggatgt 17 <210> 235 <211> 22 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 235 aactctacaa acccaaaata aa 22 <210> 236 <211> 20 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 236 gagttcgttt tgtagggcgg 20 <210> 237 <211> 14 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 237 cgggcggttt tggg 14 <210> 238 <211> 28 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 238 taaacaaccc cactcaaacc aaacaccc 28 <210> 239 <211> 28 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 239 ctatatatta taaaaattat aatccacc 28 <210> 240 <211> 19 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 240 gggttaaggt gttggtagt 19 <210> 241 <211> 24 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 241 cgttagtttt cggtaggtag gacg 24 <210> 242 <211> 15 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 242 cgcggttgtt tggcg 15 <210> 243 <211> 37 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 243 ccacccaata acaacaaaac ataccaccaa ttactaa 37 <210> 244 <211> 21 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 244 tacccttaat aaaaaaactc c 21 <210> 245 <211> 19 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 245 ttaggttgag gttggaaag 19 <210> 246 <211> 22 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 246 cgaaggggtt agttgtcgtt ga 22 <210> 247 <211> 29 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 247 cgttagtacg tagatgtaat tggttttcg 29 <210> 248 <211> 30 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 248 ctcccacacc tacaaaccaa cactccacaa 30 <210> 249 <211> 28 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 249 tggttattaa ttatgtttat ttttatag 28 <210> 250 <211> 24 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 250 accaaatatc taaatactac aacc 24 <210> 251 <211> 40 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 251 tacaaccaca aactaccaaa acccatatta aacaacacac 40 <210> 252 <211> 25 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 252 tatgcgttta acgtgttttt ttgcg 25 <210> 253 <211> 25 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 253 tggcgggttt tacgtttttt gtagt 25 <210> 254 <211> 20 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 254 ccaaaaccta aacttacaac 20 <210> 255 <211> 17 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 255 ggaaatttga ggggtaa 17 <210> 256 <211> 31 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 256 tacaacacca ccaacaaacc caaaaacaca a 31 <210> 257 <211> 17 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 257 ggcgatcgag gcgtcgt 17 <210> 258 <211> 16 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 258 gcgggtgggg agcgag 16 <210> 259 <211> 16 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 259 cccaacaaac ccacta 16 <210> 260 <211> 20 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 260 gtttagggtt aattgtgtga 20 <210> 261 <211> 34 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 261 cactacacca aacaaaaccc ctacctccac caca 34 <210> 262 <211> 20 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 262 cgtagcgtcg ggggtttagt 20 <210> 263 <211> 19 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 263 acgtcgttgc gcgtttttg 19 <210> 264 <211> 20 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 264 ccaaaaccta aacttacaac 20 <210> 265 <211> 17 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 265 ggaaatttga ggggtaa 17 <210> 266 <211> 31 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 266 tacaacacca ccaacaaacc caaaaacaca a 31 <210> 267 <211> 17 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 267 ggcgatcgag gcgtcgt 17 <210> 268 <211> 16 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 268 gcgggtgggg agcgag 16 <210> 269 <211> 17 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 269 tttggagaaa gagggat 17 <210> 270 <211> 20 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 270 aaaatcaaaa attacacctc 20 <210> 271 <211> 26 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 271 acctcccacc ctccactcaa cattca 26 <210> 272 <211> 22 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 272 cggaattgta gagcgtcggt ta 22 <210> 273 <211> 22 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 273 gttttttttt tcgcgaacgt cg 22 <210> 274 <211> 17 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 274 cggttgttgt aggcgtc 17 <210> 275 <211> 18 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 275 gcaaaacaca cgaaaacg 18 <210> 276 <211> 20 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 276 cgcgtgtgta ggtcgcgcgt 20 <210> 277 <211> 20 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 277 aaaatcctct ccaacacgtc 20 <210> 278 <211> 20 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 278 cgcgattcgt tgtttattag 20 <210> 279 <211> 25 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 279 cggatttcgc ggttaacgcg tagtt 25 <210> 280 <211> 17 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 280 cggttgttgt aggcgtc 17 <210> 281 <211> 18 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 281 gcaaaacaca cgaaaacg 18 <210> 282 <211> 20 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 282 cgcgtgtgta ggtcgcgcgt 20 <210> 283 <211> 20 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 283 aaaatcctct ccaacacgtc 20 <210> 284 <211> 20 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 284 cgcgattcgt tgtttattag 20 <210> 285 <211> 25 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 285 cggatttcgc ggttaacgcg tagtt 25 <210> 286 <211> 25 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 286 gtttttttta ttagttggaa gattt 25 <210> 287 <211> 20 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 287 aaactacaac aaaccttatc 20 <210> 288 <211> 37 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 288 ccttatccac actaaaacaa acaaacaaca cacaaac 37 <210> 289 <211> 17 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 289 cgtttacggt tcgcgcg 17 <210> 290 <211> 20 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 290 cgttcgtttg ttttagcgcg 20 <210> 291 <211> 26 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 291 gtagtagtta gtttagtatt tatttt 26 <210> 292 <211> 17 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 292 cccaccaacc atcatat 17 <210> 293 <211> 32 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 293 catcatatca aaccccacaa tcaacacaca ac 32 <210> 294 <211> 25 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 294 gttcgaaatg attttattta gttgc 25 <210> 295 <211> 17 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 295 cgttgatcgc ggggttc 17 <210> 296 <211> 17 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 296 ggggagggtt gtttatt 17 <210> 297 <211> 17 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 297 cccctccctt taactct 17 <210> 298 <211> 31 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 298 ttaactctcc ccaacaactc tcaaacccca c 31 <210> 299 <211> 24 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 299 ttagtcggag gtgaggaacg attt 24 <210> 300 <211> 24 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 300 ttatttcgtt gtcgggttta agcg 24 <210> 301 <211> 22 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 301 gtagtagtag tagggtagag ag 22 <210> 302 <211> 19 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 302 catcccccta caacctaaa 19 <210> 303 <211> 35 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 303 caacctaaac aacacactcc cacacactaa aacac 35 <210> 304 <211> 16 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 304 cgcgggagag ggcgtt 16 <210> 305 <211> 19 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 305 tgttggcgat cggcgtttt 19 <210> 306 <211> 17 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 306 gcggtttcgg agtggtt 17 <210> 307 <211> 19 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 307 cctcccgaac ctaaaacga 19 <210> 308 <211> 18 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 308 acgcccgacg aacgccaa 18 <210> 309 <211> 24 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 309 tttatgtttt tcgtttttcg ttcg 24 <210> 310 <211> 21 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 310 gaatcctcac acctccaacc g 21 <210> 311 <211> 24 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 311 cgcccactac accgcaaaca aatc 24 <210> 312 <211> 18 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 312 ttacgtgtga ggggttcg 18 <210> 313 <211> 22 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 313 acgaaaatcc accaatcgaa ac 22 <210> 314 <211> 29 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 314 tccaaatacg ataaccgata cccgaaacg 29 <210> 315 <211> 23 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 315 ggtattaggt cggtattttt cgt 23 <210> 316 <211> 23 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 316 ctattaaaaa cacgcgacat cga 23 <210> 317 <211> 23 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 317 tcgttttcgc ggttgttcgt tgt 23 <210> 318 <211> 25 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 318 ttcggaatcg gaagttcgtt gtttg 25 <210> 319 <211> 17 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 319 gcgatttcga cgtcggt 17 <210> 320 <211> 19 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 320 ctacgttctc cgcctcgtt 19 <210> 321 <211> 27 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 321 agggtcgtat ttaggttgtc gtcgtta 27 <210> 322 <211> 26 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 322 tagtcgcgaa aagaggttgg agtaag 26 <210> 323 <211> 16 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 323 gggtttcggg cgggta 16 <210> 324 <211> 21 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 324 atatcgcact cgctatcgct a 21 <210> 325 <211> 23 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 325 gagggcgacg gtacgttaga ggt 23 <210> 326 <211> 24 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 326 ttgggcgtcg ttattagttc ggtc 24 <210> 327 <211> 19 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 327 gtcgggttgg agggacgta 19 <210> 328 <211> 21 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 328 atatcgcact cgctatcgct a 21 <210> 329 <211> 23 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 329 gagggcgacg gtacgttaga ggt 23 <210> 330 <211> 24 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 330 ttgggcgtcg ttattagttc ggtc 24 <210> 331 <211> 25 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 331 gtttttttta ttagttggaa gattt 25 <210> 332 <211> 20 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 332 aaactacaac aaaccttatc 20 <210> 333 <211> 37 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 333 ccttatccac actaaaacaa acaaacaaca cacaaac 37 <210> 334 <211> 17 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 334 cgtttacggt tcgcgcg 17 <210> 335 <211> 20 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 335 cgttcgtttg ttttagcgcg 20 <210> 336 <211> 21 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 336 gaggtgttag aggagtagta g 21 <210> 337 <211> 17 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 337 tccccctaca acctaaa 17 <210> 338 <211> 37 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 338 acctaaacaa cacactccca cacactaaaa caccaat 37 <210> 339 <211> 15 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 339 cgagtcggcg cggga 15 <210> 340 <211> 20 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 340 agggcgtttt gttggcgatc 20 <210> 341 <211> 25 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 341 aaaaaaaaaa aactcctcta catac 25 <210> 342 <211> 24 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 342 ggttattgtt tgggttaata aatg 24 <210> 343 <211> 38 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 343 acatacacca caaataaatt accaaaaaca tcaaccaa 38 <210> 344 <211> 21 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 344 tttttttttt cggacgtcgt t 21 <210> 345 <211> 20 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 345 tcggtcgatg ttttcggtaa 20 <210> 346 <211> 20 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 346 tgagagagag agggttgaaa 20 <210> 347 <211> 24 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 347 tctaaataac aaaatacctc catt 24 <210> 348 <211> 27 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 348 ccattaccaa cacaacccac caaccaa 27 <210> 349 <211> 16 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 349 cgacccgcca accgac 16 <210> 350 <211> 15 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 350 cgccgaaacg cgctc 15 <210> 351 <211> 28 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 351 tggttattaa ttatgtttat ttttatag 28 <210> 352 <211> 24 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 352 accaaatatc taaatactac aacc 24 <210> 353 <211> 40 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 353 tacaaccaca aactaccaaa acccatatta aacaacacac 40 <210> 354 <211> 25 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 354 tatgcgttta acgtgttttt ttgcg 25 <210> 355 <211> 25 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 355 tggcgggttt tacgtttttt gtagt 25 <210> 356 <211> 26 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 356 gtagtagtta gtttagtatt tatttt 26 <210> 357 <211> 17 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 357 cccaccaacc atcatat 17 <210> 358 <211> 32 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 358 catcatatca aaccccacaa tcaacacaca ac 32 <210> 359 <211> 19 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 359 gaaccccgcg atcaacgcg 19 <210> 360 <211> 26 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 360 gtagtagtta gtttagtatt tatttt 26 <210> 361 <211> 17 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 361 cccaccaacc atcatat 17 <210> 362 <211> 32 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 362 catcatatca aaccccacaa tcaacacaca ac 32 <210> 363 <211> 25 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 363 gttcgaaatg attttattta gttgc 25 <210> 364 <211> 17 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 364 cgttgatcgc ggggttc 17 <210> 365 <211> 20 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 365 ccaaaaccta aacttacaac 20 <210> 366 <211> 17 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 366 ggaaatttga ggggtaa 17 <210> 367 <211> 31 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 367 tacaacacca ccaacaaacc caaaaacaca a 31 <210> 368 <211> 19 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 368 gttaattgcg ggcgatcga 19 <210> 369 <211> 17 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 369 cgtcgttagc gggtggg 17 <210> 370 <211> 17 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 370 cggttgttgt aggcgtc 17 <210> 371 <211> 18 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 371 gcaaaacaca cgaaaacg 18 <210> 372 <211> 20 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 372 cgcgtgtgta ggtcgcgcgt 20 <210> 373 <211> 20 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 373 aaaatcctct ccaacacgtc 20 <210> 374 <211> 20 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 374 cgcgattcgt tgtttattag 20 <210> 375 <211> 25 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 375 cggatttcgc ggttaacgcg tagtt 25 <210> 376 <211> 6887 <212> DNA <213> Homo Sapiens <400> 376 cgccgcccgt gggccgccgg ccggccgcag ctcgctggcg acgagggcac tacagttgct 60 ctgaccgcgt agattatgca tgtcccggcc tcgggaattt accatgcatt agaatacatt 120 agcgcctgca ttttaaaagg ctaaactatt ggctcccagc tagggactct cggtaagtgg 180 cttgttagtg acgagtgttt gtctatactg gcacatagcg gagtcttttg ctcccggctt 240 actcgcctcc aggaaagctt tggggtgagg cgaaggcgat tgaagcaatg ccccttcccc 300 cagatcgcag ctgctcaggg gggacacagc acggcatctt tcaccgaatc tctctcgctc 360 gctcgcactc cagcctccct ctccccagcg acccccccac cttctcctcc ctccctctcc 420 ttgacgtttg attccagtag caaaggaggt aaaaaaggca ccgagccgtc agccaaacct 480 gaaaagtgcg gccccgcccc ctccacagcc actggtagct tcccgtggaa ggcccgcctc 540 ccggggcagc tgcggcctcg gagtggttgc gcttggcgcc cgtcgggcgt ggccccgccc 600 caggtccggg agggtaggtt ggctgccccg gcgagcggca gagcccttct ggacagctcc 660 cgctcaccca aacagaagac gtcggcgccg gagcgggctc ggacatggcg aggctgcgag 720 ccggcccgag cggcggggcc cggtgatccc tccctccctc cccgtcccct cccctctccc 780 gcacgcacgc cccgtccgcc cccaccccgc ccccaccccg ggcgagcccg cccgcagccc 840 ggggcgcaca cccgcacgcg cactcctctc cactcactcc cgcgcccgcc cccactcccg 900 cagccgagcc ccgccacgcg cgccttgccc gcccgccggc cgcccccgcc gcccccgccg 960 cccccgggcc ctgatggact gaatgaaggc tgcctacacc gcctatcgat gcctcaccaa 1020 agacctagaa ggctgcgcca tgaacccgga gctgacaatg gaaagtctgg gcactttgca 1080 cgggccggcc ggcggcggca gtggcggggg cggcggcggg ggcggcgggg gcggcggcgg 1140 gggcccgggc catgagcagg agctgctggc cagccccagc ccccaccacg cgggccgcgg 1200 cgccgctggc tcgctgcggg gccctccgcc gcctccaacc gcgcaccagg agctgggcac 1260 ggcggcagcg gcggcagcgg cggcgtcgcg ctcggccatg gtcaccagca tggcctcgat 1320 cctggacggc ggcgactacc ggcccgagct ctccatcccg ctgcaccacg ccatgagcat 1380 gtcctgcgac tcgtctccgc ctggcatggg catgagcaac acctacacca cgctgacacc 1440 gctccagccg ctgccaccca tctccaccgt gtctgacaag ttccaccacc ctcacccgca 1500 ccaccatccg caccaccacc accaccacca ccaccagcgc ctgtccggca acgtcagcgg 1560 cagcttcacc ctcatgcgcg acgagcgcgg gctcccggcc atgaacaacc tctacagtcc 1620 ctacaaggag atgcccggca tgagccagag cctgtccccg ctggccgcca cgccgctggg 1680 caacgggcta ggcggcctcc acaacgcgca gcagagtctg cccaactacg gtccgccggg 1740 ccacgacaaa atgctcagcc ccaacttcga cgcgcaccac actgccatgc tgacccgcgg 1800 tgagcaacac ctgtcccgcg gcctgggcac cccacctgcg gccatgatgt cgcacctgaa 1860 cggcctgcac cacccgggcc acactcagtc tcacgggccg gtgctggcac ccagtcgcga 1920 gcggccaccc tcgtcctcat cgggctcgca ggtggccacg tcgggccagc tggaagaaat 1980 caacaccaaa gaggtggccc agcgcatcac agcggagctg aagcgctaca gtatccccca 2040 ggcgatcttt gcgcagaggg tgctgtgccg gtctcagggg actctctccg acctgctccg 2100 gaatccaaaa ccgtggagta aactcaaatc tggcagggag accttccgca ggatgtggaa 2160 gtggcttcag gagcccgagt tccagcgcat gtccgcctta cgcctggcag gtaaggccgg 2220 ggctagccag gggccaggct gctgggaaga gggctccggg tccggtgctt gtggcccaag 2280 tctgcgcgcc gagtcacttc tcttgattct ttccttctct ttcctataca cgtcctcttt 2340 cttctcgttt ttatttcttc ttccattttc tctttctctt ccgctcttcc cctactttcc 2400 cttctccctt ttctttttct ttcttactct ctccttgtcc ctgagctttc attgaccgac 2460 ccccccccat ttcattcgcc ctcccctcaa tgtgccaacc tttgccctat ttccgatctt 2520 cccaggtact gggaggcggg atgggggtgt gcgttttcct ctaggagccc tgtctttcca 2580 agacccacag aaaccaggac ctgcccttat tcaaaacccc atgcacttca agtctctttt 2640 agacaacaca tttcaatttt ccgggctgac tagtctccct gtgcagaggc agttgagagg 2700 ctttgctctg cagagggaaa agagctctct actctcccac ccaccatata ggcaaactta 2760 tttggtcatt ggctgaaggc acagccttgc ccccgcgggg aaccggcggc caggatacaa 2820 cagcgctcct ggagcccatc tctggccttg gcgttggcgc agggactttc tgaccgggct 2880 tgaggggctc gggccagctc caatgtcact acctacagcg agggcagggt gtaaggttga 2940 gaaggtcaca ttcaccgctt tgggaggacg tgggagaaga gactgaggtg gaaagcgctt 3000 tgccttgctc accggccgtc cttgccccgg tcccagcgtt tgctgggatt tgccaggatt 3060 tgccggggct ccgggagacc ctgagcactc gcaggaagag gtgctgagaa attaaaaatt 3120 caggttagtt aatgcatccc tgccgccggc tgcaggctcc gcctttgcat taagcgggcg 3180 ctgattgtgc gcgcctggcg accgcgggga ggactggcgg cccgcgggag gggacgggta 3240 gaggcgcggg ttacattgtt ctggagccgg ctcggctctt tgtgcctcct ctagcggcca 3300 agctgcgagg tacagccctc tattgttcta ggagcacaga aacctcctgt gtgggcggcg 3360 ggtgcgcgag ctagagggaa agatgcagta gttactgcga ctggcacgca gttgcgcgct 3420 tttgtgcgca cggaccccgc gcggtgtgcg tggcgactgc gctgccccta ggagcaagcc 3480 acgggcccag aggggcaaaa tgtccaggtc ccccgctggg aaggacacac tataccctat 3540 ggcaagccag ggtgggcgac ttcccatgga tcgggtggag gggggtatct ttcaggatcg 3600 gcgggcggtc taggggaaca attcgtggtg gcgatgattt gcatagcgcg ggtcttggga 3660 tgcgcgcggt tccgagccag cctcgcacag ctcgcttccg gagctgcgag ctcaggtttc 3720 cacccccgat cccccgggct ttcctcgcac cgctgagccc agcttgtggg gtgcactcga 3780 ccaacgcccg acagggctgg ggaatgtgac aggcagcagg ttcacccggg cttggggagg 3840 gggagtttcc gctttgacag cattttcctt tgccgtctgc tggtggattc ctattcccag 3900 tcggtaatcg ccccgcagtg ttgatctaag aaggtaaaga aaactaggtt tccctgcaaa 3960 gagcctcccc caaatcggcg gactccggat actttgagtg gatttagaaa tttatgtaat 4020 ctttctcctt tagtttattt ttcatcctct cctacagttt tctctgattt gctgttggtt 4080 cggggcaaga taaagcagcc agtagagagc gataataata gcggcgggaa atgaactgga 4140 gactggctga cagttcttaa cattttgtca tagatccccc cgaatgtccc aggctgtctc 4200 tggtgggttt tagtacccgc cggcttcttg ggcaccgggg accagaagga acttggcagc 4260 tggtcttagg ggtacagtta aaggcaggat gacagctatt ctcctgctca tctcagagcg 4320 ctgccgcccc ctcatgccgg tcgcgcaaag aacacagctt ttaaaaaaca cgtgccttct 4380 gcccatatag gtctgaaagt gatgaggaaa gtaatgcttc gcctattagc gagtttcagc 4440 ttttaaaatg atcccaagcg ttgctgagat gagaaagcgt ggcatcccgg gggtcctcag 4500 ccccacccgc gcccatggtg caagtctgca gggacaggcc cgggacagca ctgcccacgc 4560 tgctagattt tccgcagagg atcgctgaag ctgccttcgt gggagacaga atgcctcctc 4620 cagcgagtgg aaaaggcctg ctgaggaccc cgctttgctc gagcattcaa atgtgtgtct 4680 gttttattac cctgggttga aaagggacaa gagctttagc ctttttatct ggccatttta 4740 tcagcaacta caagtgtgtt gagtggttat tattacatag gaggcttttc agtttggggt 4800 cagtagatca gtctcttcag acactgatgc agaagctggg actggtaagt aggtattatg 4860 tgctcggagc gctaggggac aggagcaaat ggagaagaaa agcggaggct ttctccgccc 4920 ggagtatcga tcggaatccc cgccggtacg ccgcagaggg ccctcgccgt tgggccccgg 4980 gggtttaaca agcccagccg ctccgcaggc ggctcggccg gactctcaga ccggtgcctg 5040 gaagacaccg tccctgcccc cctcccgcca aacctgcctc ttctctttct ctcataggtt 5100 ataggttccc tttctctctc attttggccc cgcccccggg tcctgccaaa cagccaagca 5160 ggccggggtt tagggggctc agaatgaaga ggtctgattt ggccagcgcc ggcaaagctc 5220 acccttaggc gaggtcacaa cagaggcagg tccttcctgc ccagcctgcc ggtgtagtca 5280 cagccaaggg tggcacttga aaggaaaagg gagaaaactt cggagaaatt tagattgccc 5340 caacgttaga tttcagagaa attgactcca aatgcacgga ttcgttcgga aagggcggct 5400 aagtggcagg tggttgcaac cccgcccggt cgggccttcg cagaggttcc ccaagaccag 5460 cccttgcagg gcggttttca gcaacctgac aagaggcggc caagacaaat ttctgcgggt 5520 tcgagcacac actctcgggc gttgggcccc agagacctct aaaccaagca caaacaagaa 5580 gggagtgaga gaacccaggc tagaacttgc acgggcatcc cactgaggaa aagcgaggcc 5640 tcggtggcag gcatgttttc ttccgacgcc cgaaaatcga gccgagcgcc cgactacatt 5700 tactgcagag gtttccgcct ccagtgagcc cggatccccc agcggcctgc ccggagctgg 5760 tctccagtcc ccgccgtagt ccgacgcacg gccctctcct ggcagcaagc tcccagcggc 5820 cagtctgaag ccaattctgt tcaggcggcc gagggccctt agccaaccca ccatgatgtc 5880 gcctgggcca cctgatgccc gcagcggcgg gacacggccc gggcagtgcg cagtggctcc 5940 tgctaggggc accgcgtgcg tgcttgtctc ccgctgcgcc ggggacgtcc ttgggtgaca 6000 cgggccgctg ggcacctccc aagccgagga aacggacccc cttcgcagag tctcgcgccc 6060 accccccaac ctcccacctc gtttctcgct gctagggctc ccgactcagc ccacctctcc 6120 tggcggttta gttagggatc agagctggag aggctgaacg caacccgtgc cagtacggaa 6180 cagacgatat gtttgcctgc tagctgcttg gatgaataat tgaaaagttc gctgcagtct 6240 gtgcttcgtc aagtcccggg tgccgggaga acaccttccc aacacgcatc agggtgggcg 6300 ggagcgggca gaggaggcgg gacccgaggg aggagagtga acccgagcag gagaagcagc 6360 ccaggcagcc aggcgccctc gatgcgagag gctgggcatt tatttttatt ccaggctttc 6420 cactgtgtgg ttatgtcact ttctcaaaca aatgtgtata tggagggaga tcgatgctga 6480 taatgtttag aagattaaaa gagcattaat gctggcaaca ataacgtaaa cgtgtggacc 6540 cagatttcat tgatctggaa cttgatccgg cgcgtttcca gtaagcccga cggcgcgctc 6600 ttcccagcag agcgctcacc agcgccacgg ccccgcggtt ttccagcggt gccgcttcgc 6660 cagctctgcg cgggttctcc cgtctgaccg cagctcctcc cccgcgaggc cccagcccgc 6720 cttacttccc cgaggttttc tcctcctctc gcggggctct ctgccctctg caccccctcc 6780 cccgacctct gcaccacccg cccctgtgcg cacacaccgc tacttgcgct tccggcgatc 6840 cgcctgggcg gctgggtccg cgaagccaat gcgctgaacg gtgcccg 6887 <210> 377 <211> 2494 <212> DNA <213> Homo Sapiens <400> 377 tttctatgaa gttacaaagc tgcaatcccg ttctcatgtg cagcaccaca ggttttgctt 60 tcaaatatct gcaggtgcat cctcctgcac tcgttaaact aagggttttc cttttctgtg 120 ctagacccgc ttttacgacc acgctctcca cctgattcac agaaagggtt ctacgaccgt 180 caggtcaccg ccgcctttgt actttattgg ggagtcgaag gcctcagcgc tgctcgcgat 240 ttccctaagg tggtcgggaa ggtcccaacc acgttcttct gtaaaccaga taaggaaggc 300 ctggggattc cggccgcgga aaggcacaga ggaggtgaac gctccggatg cccaagtgac 360 gcacttgtag gcggattcgg aaactcgtgc tcttgagccg gaggcggagc ccccagactc 420 agaccgaccc cccagaaccg ggcggccttg cccgaggcat gaaggctttc taggcccgct 480 tctaaaagct gtgtacaatg gagactcctg gaataggcac atatctctac tgtaatcaga 540 acgagatgta acatctaaga cgcagggcag ggctctggca aagacacgct gggggaacgt 600 gaaagaaagg gccaaaacta cgcagctggt cctcagagac caaagactac gacccccagc 660 attcaatgca gtgaacccct aggacgttgc atgccgggag ctgtagtttc tcaccaccgc 720 cacccccccg cccccccgcc atctgaaagg gttctagggg atttgcaacc tctctcgtgt 780 gtttcttctt tccgagaagc gccgccacac gagaaagctg gccgcgaaag tcgtgctgga 840 atcacttcca acgaaacccc aggcatagat gggaaagggt gaagaacacg ttgccatggc 900 taccgtttcc ccggtcacgg aataaacgct ctctaggatc cggaagtagt tccgccgcga 960 cctctctaaa aggatggatg tgttctctgc ttacattcat tggacgtttt cccttagagg 1020 ccaaggccgc ccaggcaaag gggcggtccc acgtgtgagg ggcccgcgga gccatttgat 1080 tggagaaaag ctgcaaaccc tgaccaatcg gaaggagcca cgcttcgggc atcggtcacc 1140 gcacctggac agctccgatt ggtggacttc cgcccccctc acgaatcctc attgggtgcc 1200 gtgggtgcgt ggtgcggcgc gattggtggg ttcatgtttc ccgtcccccg cccgcgagaa 1260 gtgggggtga aaagcggccc gacctgcttg gggtgtagtg ggcggaccgc gcggctggag 1320 gtgtgaggat ccgaacccag gggtggaggc ggctcctgcg atcgaagggg acttgagact 1380 caccggccgc acgccatgag ggccctgtgg gtgctgggcc tctgctgcgt cctgctgacc 1440 ttcggtgagt gattctggag gagcagacgt cccccctcca cacacgcggc cgcttctcga 1500 aggtcctggg ggcgttgaac gtgggagggg ggatcccggg gcctgcggtg ggccaaggga 1560 cgtcaccatt cctcgaaaga gggcaaggga attacgttta ttctcttctt cctctggaaa 1620 taaaaaaaga gagcaacatc atctaactgc cctacagatc taatagtatc tcgcccggag 1680 gtctcagcga cctcggggtg gggcctctct gaggctctgg ctcccccggg agctgtgcga 1740 gcccctcccc cctccccgcc cggaggactt tttcggccac cgcaaccttc ggccatccca 1800 gctttcccgt cccctaattc cccagactcc gactcctcgc aagcccgtgt cccttcttag 1860 atgctggcct cgggagcgtg aggcctgggg ccagcggaat ggcagtgtca gcgtgtttga 1920 ttcagttttg ctggagttcg gttcttaaca tttctccccc ttctcatgcc tctgggctca 1980 atttcagttc ccctcgccag aggttgcata aatcctattt gcattctgac ctgtgctaac 2040 gaaggccgaa gttttggctt gatcagttgg gaggccttgg ctcggcctgc gcgcaacacg 2100 tgtgggtgta gaagaggcct ggtatcagtc tgcttaacgt tatttataaa tgatcggaga 2160 cacactgttt agaagtggtg actgcctccg tatttcagga tctactggag acctcagcat 2220 ctgaacttaa atagatgttc tgtcttggct ttacctttgg tatttaaacc agggaatgca 2280 ctctttcatc cccacctccc ttagttacca actgaatttt gcaaccccta cccttcccta 2340 tttgatcatc ctccttggag aagtgtgatg ttgaagagtt tgcccgtgtt aaatcttcag 2400 ggtcggtcag agctgacgat gaagttgatg tggatggtac agtagaagag gatctgggta 2460 aaagtagaga aggatcaagg acggatgatg aagt 2494 <210> 378 <211> 2476 <212> DNA <213> Homo Sapiens <400> 378 aattactagg aggctggggg aaaagagggg aaaaacgggt aaggaaggtt gcaaatgtta 60 agatgccaaa caggaaccca accgaagtcc gaagtgaaat acagcctcct ctggcccaac 120 tgtcatgcaa acaacttcta agcatcttca gatgtaaaga aaaacagtca ttgtgcacag 180 gcgttagctg aatgttcgag agttggatga atggggaaga cttgttatac acctagtggt 240 gggtggattt cactaggctg cagcctccac acagcttttc tttgctgcac tgcagaggcg 300 ccatcttctc cgtcttaatc ttcactcaat tcgatccttt tatctgcacc ctaaaaaaaa 360 gacccttcgg accctcccca gcatcctgtg cccccagggg aactaaacca gagtccccag 420 agctgccagg gaagaggccg cgccttaatc agacaaacgc ctccttggat gcacaggaca 480 gagcccgtgc ctccccacca tccgccactg ccctttccag acgcacatcc cactctccgc 540 cttatttcct ccccgccaag gactttacag cccagcacag aattaagcct cggaggtgat 600 ccgagggtgg gaagcagagg ggccccgagg ctccgccaga agccccggca gcgtctctgc 660 cccctcccag gcggacgcgc agccccggga agggagccgg gcgggagcct cggtggcgca 720 ctgagactaa cgcggctcgg cccacggcga gggcggggtg tcgcggcttt tgttcccgcg 780 gaccttctgc ctctcagaca gagcttaggg tgcgagcgaa ctcccgggac gtccagactt 840 ggggaaggcg cggggtggct atgggtctcc gacccctccc atttctcgca agttacacaa 900 aagggagacg cggacatgca caaagtttgc ctgtggaagg cggtgcgcga ccccgacgcc 960 ggctcgggct agggtcgcac ccaggctgcc gccgccagca gccgcgaaaa gaggttggag 1020 caaggaaggg ggatgggggt gagagaggaa ggtgaaacga ggcggagaac gcagggaaaa 1080 gcgaggggct cctagcttcc tgggctgtcc cgactcctcc tcctcctccc cagggcccaa 1140 gagaaaggaa agggcaacga ttcaagagcg aaggactggc tttagggacg ctgcgttttc 1200 ggttttcccc acgtgctcct tcccccttcc cccctgtctg aatgtctctc gcctcccccg 1260 acccccgctt ccaaggcagg gactaagtcg gggtctgggc tcagggtcgc cccctaccct 1320 tctcgccccg ggctggcgcg gaaccaggga gaccagcgcc tcgcccgctc cctctcagcg 1380 ggccggagcg cgactccctg gggcagggct gggccgaaag cggggatgcg ctggacgtcc 1440 gcaagcgggg gcggagagga gaggggtccc attgacggac ccccggcttc tctgcattaa 1500 agacttgggt taaggtcttg gggggtatcg cgtccccacc gtgcagcctc cccccgcctt 1560 ccgaggcgcg gcacccacct ccagcgcccg agccgtccag gcggccagca ggagcagtgc 1620 caaaccgggc agcatcgcga ccctgcgcgg ggcaccgagt gcgctgctgt gcgagtggga 1680 tccgccgcgt ccttgctctg cccgcgccgc caccgccgcc gtctcccggg gcccccgcgc 1740 acgctcctcc gcgtgctctc gcctaccgct gccgaggaaa ctgacggagc ccgagcgcgg 1800 cggcggggct cagagccagg cgagtcagct gatccggccc accccgctcg gcacccgaga 1860 gagaccccta gcggcgccgc cggggaactg cgcccgctcg cgccgggagg ggccctcgcg 1920 ccccgcgccc acaggtgcac gcgcccttgg cgccgcctgc accccacgcg ccccctccgc 1980 tccccggccg acggcccacc tgggcttcgt gaacagtggg agggagagtc tggggccagg 2040 agagggacgg tgcaggatca gggaaaggtg agtcctagga cgctgaggct ctagaaaagt 2100 cgagagcgct cctgctcgtc cccgtgagct tgaatcatcc gaccccgcag gcctcccggg 2160 ggtgtcgtat aaaggactgc tgctagggtg cgtttttatc cgcatttcgt tttttctctc 2220 ggtttggaga ggtggggcag gcgtttctgg aagagaatga gaacgagtga agcttaaagg 2280 aaataggatt ttctttgctt gttgagacag caaaacctca ttttttaacc cccaacgtca 2340 aaagcaggca cgagcaacct ggaatttcta tctttagaac gaaccaaagg agcaaggcgc 2400 aggacctggc aaagaagcgg ccaacccatt tacttcttct tgaaagcagg gttctgggct 2460 tgggttttgt ttcttt 2476 <210> 379 <211> 6887 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 379 cgtcgttcgt gggtcgtcgg tcggtcgtag ttcgttggcg acgagggtat tatagttgtt 60 ttgatcgcgt agattatgta tgtttcggtt tcgggaattt attatgtatt agaatatatt 120 agcgtttgta ttttaaaagg ttaaattatt ggtttttagt tagggatttt cggtaagtgg 180 tttgttagtg acgagtgttt gtttatattg gtatatagcg gagttttttg ttttcggttt 240 attcgttttt aggaaagttt tggggtgagg cgaaggcgat tgaagtaatg tttttttttt 300 tagatcgtag ttgtttaggg gggatatagt acggtatttt ttatcgaatt tttttcgttc 360 gttcgtattt tagttttttt ttttttagcg atttttttat tttttttttt tttttttttt 420 ttgacgtttg attttagtag taaaggaggt aaaaaaggta tcgagtcgtt agttaaattt 480 gaaaagtgcg gtttcgtttt ttttatagtt attggtagtt tttcgtggaa ggttcgtttt 540 tcggggtagt tgcggtttcg gagtggttgc gtttggcgtt cgtcgggcgt ggtttcgttt 600 taggttcggg agggtaggtt ggttgtttcg gcgagcggta gagttttttt ggatagtttt 660 cgtttattta aatagaagac gtcggcgtcg gagcgggttc ggatatggcg aggttgcgag 720 tcggttcgag cggcggggtt cggtgatttt tttttttttt ttcgtttttt tttttttttc 780 gtacgtacgt ttcgttcgtt tttatttcgt ttttatttcg ggcgagttcg ttcgtagttc 840 ggggcgtata ttcgtacgcg tatttttttt tatttatttt cgcgttcgtt tttattttcg 900 tagtcgagtt tcgttacgcg cgttttgttc gttcgtcggt cgttttcgtc gttttcgtcg 960 ttttcgggtt ttgatggatt gaatgaaggt tgtttatatc gtttatcgat gttttattaa 1020 agatttagaa ggttgcgtta tgaattcgga gttgataatg gaaagtttgg gtattttgta 1080 cgggtcggtc ggcggcggta gtggcggggg cggcggcggg ggcggcgggg gcggcggcgg 1140 gggttcgggt tatgagtagg agttgttggt tagttttagt ttttattacg cgggtcgcgg 1200 cgtcgttggt tcgttgcggg gtttttcgtc gtttttaatc gcgtattagg agttgggtac 1260 ggcggtagcg gcggtagcgg cggcgtcgcg ttcggttatg gttattagta tggtttcgat 1320 tttggacggc ggcgattatc ggttcgagtt ttttatttcg ttgtattacg ttatgagtat 1380 gttttgcgat tcgttttcgt ttggtatggg tatgagtaat atttatatta cgttgatatc 1440 gttttagtcg ttgttattta tttttatcgt gtttgataag ttttattatt tttattcgta 1500 ttattattcg tattattatt attattatta ttattagcgt ttgttcggta acgttagcgg 1560 tagttttatt tttatgcgcg acgagcgcgg gttttcggtt atgaataatt tttatagttt 1620 ttataaggag atgttcggta tgagttagag tttgttttcg ttggtcgtta cgtcgttggg 1680 taacgggtta ggcggttttt ataacgcgta gtagagtttg tttaattacg gttcgtcggg 1740 ttacgataaa atgtttagtt ttaatttcga cgcgtattat attgttatgt tgattcgcgg 1800 tgagtaatat ttgtttcgcg gtttgggtat tttatttgcg gttatgatgt cgtatttgaa 1860 cggtttgtat tattcgggtt atatttagtt ttacgggtcg gtgttggtat ttagtcgcga 1920 gcggttattt tcgtttttat cgggttcgta ggtggttacg tcgggttagt tggaagaaat 1980 taatattaaa gaggtggttt agcgtattat agcggagttg aagcgttata gtatttttta 2040 ggcgattttt gcgtagaggg tgttgtgtcg gttttagggg atttttttcg atttgtttcg 2100 gaatttaaaa tcgtggagta aatttaaatt tggtagggag atttttcgta ggatgtggaa 2160 gtggttttag gagttcgagt tttagcgtat gttcgtttta cgtttggtag gtaaggtcgg 2220 ggttagttag gggttaggtt gttgggaaga gggtttcggg ttcggtgttt gtggtttaag 2280 tttgcgcgtc gagttatttt ttttgatttt tttttttttt tttttatata cgtttttttt 2340 tttttcgttt ttattttttt ttttattttt tttttttttt tcgttttttt tttatttttt 2400 tttttttttt tttttttttt tttttatttt ttttttgttt ttgagttttt attgatcgat 2460 ttttttttat tttattcgtt ttttttttaa tgtgttaatt tttgttttat tttcgatttt 2520 tttaggtatt gggaggcggg atgggggtgt gcgttttttt ttaggagttt tgttttttta 2580 agatttatag aaattaggat ttgtttttat ttaaaatttt atgtatttta agtttttttt 2640 agataatata ttttaatttt tcgggttgat tagttttttt gtgtagaggt agttgagagg 2700 ttttgttttg tagagggaaa agagtttttt atttttttat ttattatata ggtaaattta 2760 tttggttatt ggttgaaggt atagttttgt tttcgcgggg aatcggcggt taggatataa 2820 tagcgttttt ggagtttatt tttggttttg gcgttggcgt agggattttt tgatcgggtt 2880 tgaggggttc gggttagttt taatgttatt atttatagcg agggtagggt gtaaggttga 2940 gaaggttata tttatcgttt tgggaggacg tgggagaaga gattgaggtg gaaagcgttt 3000 tgttttgttt atcggtcgtt tttgtttcgg ttttagcgtt tgttgggatt tgttaggatt 3060 tgtcggggtt tcgggagatt ttgagtattc gtaggaagag gtgttgagaa attaaaaatt 3120 taggttagtt aatgtatttt tgtcgtcggt tgtaggtttc gtttttgtat taagcgggcg 3180 ttgattgtgc gcgtttggcg atcgcgggga ggattggcgg ttcgcgggag gggacgggta 3240 gaggcgcggg ttatattgtt ttggagtcgg ttcggttttt tgtgtttttt ttagcggtta 3300 agttgcgagg tatagttttt tattgtttta ggagtataga aattttttgt gtgggcggcg 3360 ggtgcgcgag ttagagggaa agatgtagta gttattgcga ttggtacgta gttgcgcgtt 3420 tttgtgcgta cggatttcgc gcggtgtgcg tggcgattgc gttgttttta ggagtaagtt 3480 acgggtttag aggggtaaaa tgtttaggtt tttcgttggg aaggatatat tatattttat 3540 ggtaagttag ggtgggcgat tttttatgga tcgggtggag gggggtattt tttaggatcg 3600 gcgggcggtt taggggaata attcgtggtg gcgatgattt gtatagcgcg ggttttggga 3660 tgcgcgcggt ttcgagttag tttcgtatag ttcgttttcg gagttgcgag tttaggtttt 3720 tattttcgat ttttcgggtt tttttcgtat cgttgagttt agtttgtggg gtgtattcga 3780 ttaacgttcg atagggttgg ggaatgtgat aggtagtagg tttattcggg tttggggagg 3840 gggagttttc gttttgatag tatttttttt tgtcgtttgt tggtggattt ttatttttag 3900 tcggtaatcg tttcgtagtg ttgatttaag aaggtaaaga aaattaggtt tttttgtaaa 3960 gagttttttt taaatcggcg gatttcggat attttgagtg gatttagaaa tttatgtaat 4020 tttttttttt tagtttattt tttatttttt tttatagttt tttttgattt gttgttggtt 4080 cggggtaaga taaagtagtt agtagagagc gataataata gcggcgggaa atgaattgga 4140 gattggttga tagtttttaa tattttgtta tagatttttt cgaatgtttt aggttgtttt 4200 tggtgggttt tagtattcgt cggttttttg ggtatcgggg attagaagga atttggtagt 4260 tggttttagg ggtatagtta aaggtaggat gatagttatt tttttgttta ttttagagcg 4320 ttgtcgtttt tttatgtcgg tcgcgtaaag aatatagttt ttaaaaaata cgtgtttttt 4380 gtttatatag gtttgaaagt gatgaggaaa gtaatgtttc gtttattagc gagttttagt 4440 ttttaaaatg attttaagcg ttgttgagat gagaaagcgt ggtatttcgg gggtttttag 4500 ttttattcgc gtttatggtg taagtttgta gggataggtt cgggatagta ttgtttacgt 4560 tgttagattt ttcgtagagg atcgttgaag ttgttttcgt gggagataga atgttttttt 4620 tagcgagtgg aaaaggtttg ttgaggattt cgttttgttc gagtatttaa atgtgtgttt 4680 gttttattat tttgggttga aaagggataa gagttttagt ttttttattt ggttatttta 4740 ttagtaatta taagtgtgtt gagtggttat tattatatag gaggtttttt agtttggggt 4800 tagtagatta gtttttttag atattgatgt agaagttggg attggtaagt aggtattatg 4860 tgttcggagc gttaggggat aggagtaaat ggagaagaaa agcggaggtt tttttcgttc 4920 ggagtatcga tcggaatttt cgtcggtacg tcgtagaggg ttttcgtcgt tgggtttcgg 4980 gggtttaata agtttagtcg tttcgtaggc ggttcggtcg gatttttaga tcggtgtttg 5040 gaagatatcg tttttgtttt tttttcgtta aatttgtttt tttttttttt tttataggtt 5100 ataggttttt tttttttttt attttggttt cgttttcggg ttttgttaaa tagttaagta 5160 ggtcggggtt tagggggttt agaatgaaga ggtttgattt ggttagcgtc ggtaaagttt 5220 atttttaggc gaggttataa tagaggtagg ttttttttgt ttagtttgtc ggtgtagtta 5280 tagttaaggg tggtatttga aaggaaaagg gagaaaattt cggagaaatt tagattgttt 5340 taacgttaga ttttagagaa attgatttta aatgtacgga ttcgttcgga aagggcggtt 5400 aagtggtagg tggttgtaat ttcgttcggt cgggttttcg tagaggtttt ttaagattag 5460 tttttgtagg gcggttttta gtaatttgat aagaggcggt taagataaat ttttgcgggt 5520 tcgagtatat attttcgggc gttgggtttt agagattttt aaattaagta taaataagaa 5580 gggagtgaga gaatttaggt tagaatttgt acgggtattt tattgaggaa aagcgaggtt 5640 tcggtggtag gtatgttttt tttcgacgtt cgaaaatcga gtcgagcgtt cgattatatt 5700 tattgtagag gttttcgttt ttagtgagtt cggatttttt agcggtttgt tcggagttgg 5760 tttttagttt tcgtcgtagt tcgacgtacg gttttttttt ggtagtaagt ttttagcggt 5820 tagtttgaag ttaattttgt ttaggcggtc gagggttttt agttaattta ttatgatgtc 5880 gtttgggtta tttgatgttc gtagcggcgg gatacggttc gggtagtgcg tagtggtttt 5940 tgttaggggt atcgcgtgcg tgtttgtttt tcgttgcgtc ggggacgttt ttgggtgata 6000 cgggtcgttg ggtatttttt aagtcgagga aacggatttt tttcgtagag tttcgcgttt 6060 attttttaat tttttatttc gtttttcgtt gttagggttt tcgatttagt ttattttttt 6120 tggcggttta gttagggatt agagttggag aggttgaacg taattcgtgt tagtacggaa 6180 tagacgatat gtttgtttgt tagttgtttg gatgaataat tgaaaagttc gttgtagttt 6240 gtgtttcgtt aagtttcggg tgtcgggaga atattttttt aatacgtatt agggtgggcg 6300 ggagcgggta gaggaggcgg gattcgaggg aggagagtga attcgagtag gagaagtagt 6360 ttaggtagtt aggcgttttc gatgcgagag gttgggtatt tatttttatt ttaggttttt 6420 tattgtgtgg ttatgttatt tttttaaata aatgtgtata tggagggaga tcgatgttga 6480 taatgtttag aagattaaaa gagtattaat gttggtaata ataacgtaaa cgtgtggatt 6540 tagattttat tgatttggaa tttgattcgg cgcgttttta gtaagttcga cggcgcgttt 6600 tttttagtag agcgtttatt agcgttacgg tttcgcggtt ttttagcggt gtcgtttcgt 6660 tagttttgcg cgggtttttt cgtttgatcg tagttttttt ttcgcgaggt tttagttcgt 6720 tttatttttt cgaggttttt tttttttttc gcggggtttt ttgttttttg tatttttttt 6780 ttcgattttt gtattattcg tttttgtgcg tatatatcgt tatttgcgtt ttcggcgatt 6840 cgtttgggcg gttgggttcg cgaagttaat gcgttgaacg gtgttcg 6887 <210> 380 <211> 6887 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 380 cgggtatcgt ttagcgtatt ggtttcgcgg atttagtcgt ttaggcggat cgtcggaagc 60 gtaagtagcg gtgtgtgcgt ataggggcgg gtggtgtaga ggtcggggga gggggtgtag 120 agggtagaga gtttcgcgag aggaggagaa aatttcgggg aagtaaggcg ggttggggtt 180 tcgcggggga ggagttgcgg ttagacggga gaattcgcgt agagttggcg aagcggtatc 240 gttggaaaat cgcggggtcg tggcgttggt gagcgttttg ttgggaagag cgcgtcgtcg 300 ggtttattgg aaacgcgtcg gattaagttt tagattaatg aaatttgggt ttatacgttt 360 acgttattgt tgttagtatt aatgtttttt taatttttta aatattatta gtatcgattt 420 ttttttatat atatatttgt ttgagaaagt gatataatta tatagtggaa agtttggaat 480 aaaaataaat gtttagtttt tcgtatcgag ggcgtttggt tgtttgggtt gttttttttg 540 ttcgggttta tttttttttt tcgggtttcg ttttttttgt tcgttttcgt ttattttgat 600 gcgtgttggg aaggtgtttt ttcggtattc gggatttgac gaagtataga ttgtagcgaa 660 ttttttaatt atttatttaa gtagttagta ggtaaatata tcgtttgttt cgtattggta 720 cgggttgcgt ttagtttttt tagttttgat ttttaattaa atcgttagga gaggtgggtt 780 gagtcgggag ttttagtagc gagaaacgag gtgggaggtt ggggggtggg cgcgagattt 840 tgcgaagggg gttcgttttt tcggtttggg aggtgtttag cggttcgtgt tatttaagga 900 cgttttcggc gtagcgggag ataagtacgt acgcggtgtt tttagtagga gttattgcgt 960 attgttcggg tcgtgtttcg tcgttgcggg tattaggtgg tttaggcgat attatggtgg 1020 gttggttaag ggttttcggt cgtttgaata gaattggttt tagattggtc gttgggagtt 1080 tgttgttagg agagggtcgt gcgtcggatt acggcgggga ttggagatta gtttcgggta 1140 ggtcgttggg ggattcgggt ttattggagg cggaaatttt tgtagtaaat gtagtcgggc 1200 gttcggttcg attttcgggc gtcggaagaa aatatgtttg ttatcgaggt ttcgtttttt 1260 tttagtggga tgttcgtgta agttttagtt tgggtttttt tatttttttt ttgtttgtgt 1320 ttggtttaga ggtttttggg gtttaacgtt cgagagtgtg tgttcgaatt cgtagaaatt 1380 tgttttggtc gttttttgtt aggttgttga aaatcgtttt gtaagggttg gttttgggga 1440 atttttgcga aggttcgatc gggcggggtt gtaattattt gttatttagt cgtttttttc 1500 gaacgaattc gtgtatttgg agttaatttt tttgaaattt aacgttgggg taatttaaat 1560 tttttcgaag tttttttttt ttttttttta agtgttattt ttggttgtga ttatatcggt 1620 aggttgggta ggaaggattt gtttttgttg tgatttcgtt taagggtgag ttttgtcggc 1680 gttggttaaa ttagattttt ttattttgag ttttttaaat ttcggtttgt ttggttgttt 1740 ggtaggattc gggggcgggg ttaaaatgag agagaaaggg aatttataat ttatgagaga 1800 aagagaagag gtaggtttgg cgggaggggg gtagggacgg tgttttttag gtatcggttt 1860 gagagttcgg tcgagtcgtt tgcggagcgg ttgggtttgt taaattttcg gggtttaacg 1920 gcgagggttt tttgcggcgt atcggcgggg atttcgatcg atatttcggg cggagaaagt 1980 tttcgttttt tttttttatt tgtttttgtt ttttagcgtt tcgagtatat aatatttatt 2040 tattagtttt agtttttgta ttagtgtttg aagagattga tttattgatt ttaaattgaa 2100 aagtttttta tgtaataata attatttaat atatttgtag ttgttgataa aatggttaga 2160 taaaaaggtt aaagtttttg ttttttttta atttagggta ataaaataga tatatatttg 2220 aatgttcgag taaagcgggg tttttagtag gtttttttta ttcgttggag gaggtatttt 2280 gttttttacg aaggtagttt tagcgatttt ttgcggaaaa tttagtagcg tgggtagtgt 2340 tgtttcgggt ttgtttttgt agatttgtat tatgggcgcg ggtggggttg aggattttcg 2400 ggatgttacg tttttttatt ttagtaacgt ttgggattat tttaaaagtt gaaattcgtt 2460 aataggcgaa gtattatttt ttttattatt tttagattta tatgggtaga aggtacgtgt 2520 tttttaaaag ttgtgttttt tgcgcgatcg gtatgagggg gcggtagcgt tttgagatga 2580 gtaggagaat agttgttatt ttgtttttaa ttgtattttt aagattagtt gttaagtttt 2640 ttttggtttt cggtgtttaa gaagtcggcg ggtattaaaa tttattagag atagtttggg 2700 atattcgggg ggatttatga taaaatgtta agaattgtta gttagttttt agtttatttt 2760 tcgtcgttat tattatcgtt ttttattggt tgttttattt tgtttcgaat taatagtaaa 2820 ttagagaaaa ttgtaggaga ggatgaaaaa taaattaaag gagaaagatt atataaattt 2880 ttaaatttat ttaaagtatt cggagttcgt cgatttgggg gaggtttttt gtagggaaat 2940 ttagtttttt ttattttttt agattaatat tgcggggcga ttatcgattg ggaataggaa 3000 tttattagta gacggtaaag gaaaatgttg ttaaagcgga aatttttttt ttttaagttc 3060 gggtgaattt gttgtttgtt atatttttta gttttgtcgg gcgttggtcg agtgtatttt 3120 ataagttggg tttagcggtg cgaggaaagt tcgggggatc gggggtggaa atttgagttc 3180 gtagtttcgg aagcgagttg tgcgaggttg gttcggaatc gcgcgtattt taagattcgc 3240 gttatgtaaa ttatcgttat tacgaattgt ttttttagat cgttcgtcga ttttgaaaga 3300 tatttttttt tattcgattt atgggaagtc gtttattttg gtttgttata gggtatagtg 3360 tgtttttttt agcgggggat ttggatattt tgtttttttg ggttcgtggt ttgtttttag 3420 gggtagcgta gtcgttacgt atatcgcgcg gggttcgtgc gtataaaagc gcgtaattgc 3480 gtgttagtcg tagtaattat tgtatttttt tttttagttc gcgtattcgt cgtttatata 3540 ggaggttttt gtgtttttag aataatagag ggttgtattt cgtagtttgg tcgttagagg 3600 aggtataaag agtcgagtcg gttttagaat aatgtaattc gcgtttttat tcgttttttt 3660 tcgcgggtcg ttagtttttt tcgcggtcgt taggcgcgta taattagcgt tcgtttaatg 3720 taaaggcgga gtttgtagtc ggcggtaggg atgtattaat taatttgaat ttttaatttt 3780 ttagtatttt tttttgcgag tgtttagggt ttttcggagt ttcggtaaat tttggtaaat 3840 tttagtaaac gttgggatcg gggtaaggac ggtcggtgag taaggtaaag cgttttttat 3900 tttagttttt ttttttacgt ttttttaaag cggtgaatgt gattttttta attttatatt 3960 ttgttttcgt tgtaggtagt gatattggag ttggttcgag ttttttaagt tcggttagaa 4020 agtttttgcg ttaacgttaa ggttagagat gggttttagg agcgttgttg tattttggtc 4080 gtcggttttt cgcgggggta aggttgtgtt tttagttaat gattaaataa gtttgtttat 4140 atggtgggtg ggagagtaga gagttttttt ttttttgtag agtaaagttt tttaattgtt 4200 tttgtatagg gagattagtt agttcggaaa attgaaatgt gttgtttaaa agagatttga 4260 agtgtatggg gttttgaata agggtaggtt ttggtttttg tgggttttgg aaagataggg 4320 tttttagagg aaaacgtata tttttatttc gttttttagt atttgggaag atcggaaata 4380 gggtaaaggt tggtatattg aggggagggc gaatgaaatg ggggggggtc ggttaatgaa 4440 agtttaggga taaggagaga gtaagaaaga aaaagaaaag ggagaaggga aagtagggga 4500 agagcggaag agaaagagaa aatggaagaa gaaataaaaa cgagaagaaa gaggacgtgt 4560 ataggaaaga gaaggaaaga attaagagaa gtgattcggc gcgtagattt gggttataag 4620 tatcggattc ggagtttttt ttttagtagt ttggtttttg gttagtttcg gttttatttg 4680 ttaggcgtaa ggcggatatg cgttggaatt cgggtttttg aagttatttt tatattttgc 4740 ggaaggtttt tttgttagat ttgagtttat tttacggttt tggatttcgg agtaggtcgg 4800 agagagtttt ttgagatcgg tatagtattt tttgcgtaaa gatcgtttgg gggatattgt 4860 agcgttttag tttcgttgtg atgcgttggg ttattttttt ggtgttgatt ttttttagtt 4920 ggttcgacgt ggttatttgc gagttcgatg aggacgaggg tggtcgttcg cgattgggtg 4980 ttagtatcgg ttcgtgagat tgagtgtggt tcgggtggtg taggtcgttt aggtgcgata 5040 ttatggtcgt aggtggggtg tttaggtcgc gggataggtg ttgtttatcg cgggttagta 5100 tggtagtgtg gtgcgcgtcg aagttggggt tgagtatttt gtcgtggttc ggcggatcgt 5160 agttgggtag attttgttgc gcgttgtgga ggtcgtttag ttcgttgttt agcggcgtgg 5220 cggttagcgg ggataggttt tggtttatgt cgggtatttt tttgtaggga ttgtagaggt 5280 tgtttatggt cgggagttcg cgttcgtcgc gtatgagggt gaagttgtcg ttgacgttgt 5340 cggataggcg ttggtggtgg tggtggtggt ggtggtgcgg atggtggtgc gggtgagggt 5400 ggtggaattt gttagatacg gtggagatgg gtggtagcgg ttggagcggt gttagcgtgg 5460 tgtaggtgtt gtttatgttt atgttaggcg gagacgagtc gtaggatatg tttatggcgt 5520 ggtgtagcgg gatggagagt tcgggtcggt agtcgtcgtc gtttaggatc gaggttatgt 5580 tggtgattat ggtcgagcgc gacgtcgtcg ttgtcgtcgt tgtcgtcgtg tttagttttt 5640 ggtgcgcggt tggaggcggc ggagggtttc gtagcgagtt agcggcgtcg cggttcgcgt 5700 ggtgggggtt ggggttggtt agtagttttt gtttatggtt cgggttttcg tcgtcgtttt 5760 cgtcgttttc gtcgtcgttt tcgttattgt cgtcgtcggt cggttcgtgt aaagtgttta 5820 gattttttat tgttagtttc gggtttatgg cgtagttttt taggtttttg gtgaggtatc 5880 gataggcggt gtaggtagtt tttatttagt ttattagggt tcgggggcgg cgggggcggc 5940 gggggcggtc ggcgggcggg taaggcgcgc gtggcggggt tcggttgcgg gagtgggggc 6000 gggcgcggga gtgagtggag aggagtgcgc gtgcgggtgt gcgtttcggg ttgcgggcgg 6060 gttcgttcgg ggtgggggcg gggtgggggc ggacggggcg tgcgtgcggg agaggggagg 6120 ggacggggag ggagggaggg attatcgggt ttcgtcgttc gggtcggttc gtagtttcgt 6180 tatgttcgag ttcgtttcgg cgtcgacgtt ttttgtttgg gtgagcggga gttgtttaga 6240 agggttttgt cgttcgtcgg ggtagttaat ttattttttc ggatttgggg cggggttacg 6300 ttcgacgggc gttaagcgta attatttcga ggtcgtagtt gtttcgggag gcgggttttt 6360 tacgggaagt tattagtggt tgtggagggg gcggggtcgt attttttagg tttggttgac 6420 ggttcggtgt tttttttatt ttttttgtta ttggaattaa acgttaagga gagggaggga 6480 ggagaaggtg ggggggtcgt tggggagagg gaggttggag tgcgagcgag cgagagagat 6540 tcggtgaaag atgtcgtgtt gtgttttttt tgagtagttg cgatttgggg gaaggggtat 6600 tgttttaatc gttttcgttt tattttaaag tttttttgga ggcgagtaag tcgggagtaa 6660 aagatttcgt tatgtgttag tatagataaa tattcgttat taataagtta tttatcgaga 6720 gtttttagtt gggagttaat agtttagttt tttaaaatgt aggcgttaat gtattttaat 6780 gtatggtaaa ttttcgaggt cgggatatgt ataatttacg cggttagagt aattgtagtg 6840 ttttcgtcgt tagcgagttg cggtcggtcg gcggtttacg ggcggcg 6887 <210> 381 <211> 2494 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 381 tttttatgaa gttataaagt tgtaatttcg tttttatgtg tagtattata ggttttgttt 60 ttaaatattt gtaggtgtat ttttttgtat tcgttaaatt aagggttttt tttttttgtg 120 ttagattcgt ttttacgatt acgtttttta tttgatttat agaaagggtt ttacgatcgt 180 taggttatcg tcgtttttgt attttattgg ggagtcgaag gttttagcgt tgttcgcgat 240 ttttttaagg tggtcgggaa ggttttaatt acgttttttt gtaaattaga taaggaaggt 300 ttggggattt cggtcgcgga aaggtataga ggaggtgaac gtttcggatg tttaagtgac 360 gtatttgtag gcggattcgg aaattcgtgt ttttgagtcg gaggcggagt ttttagattt 420 agatcgattt tttagaatcg ggcggttttg ttcgaggtat gaaggttttt taggttcgtt 480 tttaaaagtt gtgtataatg gagatttttg gaataggtat atatttttat tgtaattaga 540 acgagatgta atatttaaga cgtagggtag ggttttggta aagatacgtt gggggaacgt 600 gaaagaaagg gttaaaatta cgtagttggt ttttagagat taaagattac gatttttagt 660 atttaatgta gtgaattttt aggacgttgt atgtcgggag ttgtagtttt ttattatcgt 720 tattttttcg ttttttcgtt atttgaaagg gttttagggg atttgtaatt tttttcgtgt 780 gttttttttt ttcgagaagc gtcgttatac gagaaagttg gtcgcgaaag tcgtgttgga 840 attattttta acgaaatttt aggtatagat gggaaagggt gaagaatacg ttgttatggt 900 tatcgttttt tcggttacgg aataaacgtt ttttaggatt cggaagtagt ttcgtcgcga 960 tttttttaaa aggatggatg tgttttttgt ttatatttat tggacgtttt tttttagagg 1020 ttaaggtcgt ttaggtaaag gggcggtttt acgtgtgagg ggttcgcgga gttatttgat 1080 tggagaaaag ttgtaaattt tgattaatcg gaaggagtta cgtttcgggt atcggttatc 1140 gtatttggat agtttcgatt ggtggatttt cgtttttttt acgaattttt attgggtgtc 1200 gtgggtgcgt ggtgcggcgc gattggtggg tttatgtttt tcgtttttcg ttcgcgagaa 1260 gtgggggtga aaagcggttc gatttgtttg gggtgtagtg ggcggatcgc gcggttggag 1320 gtgtgaggat tcgaatttag gggtggaggc ggtttttgcg atcgaagggg atttgagatt 1380 tatcggtcgt acgttatgag ggttttgtgg gtgttgggtt tttgttgcgt tttgttgatt 1440 ttcggtgagt gattttggag gagtagacgt ttttttttta tatacgcggt cgtttttcga 1500 aggttttggg ggcgttgaac gtgggagggg ggatttcggg gtttgcggtg ggttaaggga 1560 cgttattatt tttcgaaaga gggtaaggga attacgttta tttttttttt tttttggaaa 1620 taaaaaaaga gagtaatatt atttaattgt tttatagatt taatagtatt tcgttcggag 1680 gttttagcga tttcggggtg gggttttttt gaggttttgg ttttttcggg agttgtgcga 1740 gttttttttt ttttttcgtt cggaggattt tttcggttat cgtaattttc ggttatttta 1800 gttttttcgt tttttaattt tttagatttc gatttttcgt aagttcgtgt ttttttttag 1860 atgttggttt cgggagcgtg aggtttgggg ttagcggaat ggtagtgtta gcgtgtttga 1920 tttagttttg ttggagttcg gtttttaata tttttttttt tttttatgtt tttgggttta 1980 attttagttt ttttcgttag aggttgtata aattttattt gtattttgat ttgtgttaac 2040 gaaggtcgaa gttttggttt gattagttgg gaggttttgg ttcggtttgc gcgtaatacg 2100 tgtgggtgta gaagaggttt ggtattagtt tgtttaacgt tatttataaa tgatcggaga 2160 tatattgttt agaagtggtg attgttttcg tattttagga tttattggag attttagtat 2220 ttgaatttaa atagatgttt tgttttggtt ttatttttgg tatttaaatt agggaatgta 2280 tttttttatt tttatttttt ttagttatta attgaatttt gtaattttta ttttttttta 2340 tttgattatt ttttttggag aagtgtgatg ttgaagagtt tgttcgtgtt aaatttttag 2400 ggtcggttag agttgacgat gaagttgatg tggatggtat agtagaagag gatttgggta 2460 aaagtagaga aggattaagg acggatgatg aagt 2494 <210> 382 <211> 2494 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 382 attttattat tcgtttttga ttttttttta tttttattta gatttttttt tattgtatta 60 tttatattaa ttttatcgtt agttttgatc gattttgaag atttaatacg ggtaaatttt 120 ttaatattat atttttttaa ggaggatgat taaataggga agggtagggg ttgtaaaatt 180 tagttggtaa ttaagggagg tggggatgaa agagtgtatt ttttggttta aatattaaag 240 gtaaagttaa gatagaatat ttatttaagt ttagatgttg aggtttttag tagattttga 300 aatacggagg tagttattat ttttaaatag tgtgttttcg attatttata aataacgtta 360 agtagattga tattaggttt tttttatatt tatacgtgtt gcgcgtaggt cgagttaagg 420 ttttttaatt gattaagtta aaatttcggt tttcgttagt ataggttaga atgtaaatag 480 gatttatgta atttttggcg aggggaattg aaattgagtt tagaggtatg agaaggggga 540 gaaatgttaa gaatcgaatt ttagtaaaat tgaattaaat acgttgatat tgttatttcg 600 ttggttttag gttttacgtt ttcgaggtta gtatttaaga agggatacgg gtttgcgagg 660 agtcggagtt tggggaatta ggggacggga aagttgggat ggtcgaaggt tgcggtggtc 720 gaaaaagttt ttcgggcggg gaggggggag gggttcgtat agttttcggg ggagttagag 780 ttttagagag gttttatttc gaggtcgttg agattttcgg gcgagatatt attagatttg 840 tagggtagtt agatgatgtt gttttttttt tttattttta gaggaagaag agaataaacg 900 taattttttt gttttttttc gaggaatggt gacgtttttt ggtttatcgt aggtttcggg 960 attttttttt ttacgtttaa cgtttttagg attttcgaga agcggtcgcg tgtgtggagg 1020 ggggacgttt gtttttttag aattatttat cgaaggttag taggacgtag tagaggttta 1080 gtatttatag ggtttttatg gcgtgcggtc ggtgagtttt aagttttttt cgatcgtagg 1140 agtcgttttt atttttgggt tcggattttt atatttttag tcgcgcggtt cgtttattat 1200 attttaagta ggtcgggtcg ttttttattt ttatttttcg cgggcggggg acgggaaata 1260 tgaatttatt aatcgcgtcg tattacgtat ttacggtatt taatgaggat tcgtgagggg 1320 ggcggaagtt tattaatcgg agttgtttag gtgcggtgat cgatgttcga agcgtggttt 1380 ttttcgattg gttagggttt gtagtttttt tttaattaaa tggtttcgcg ggttttttat 1440 acgtgggatc gtttttttgt ttgggcggtt ttggttttta agggaaaacg tttaatgaat 1500 gtaagtagag aatatattta tttttttaga gaggtcgcgg cggaattatt ttcggatttt 1560 agagagcgtt tatttcgtga tcggggaaac ggtagttatg gtaacgtgtt ttttattttt 1620 ttttatttat gtttggggtt tcgttggaag tgattttagt acgattttcg cggttagttt 1680 tttcgtgtgg cggcgttttt cggaaagaag aaatatacga gagaggttgt aaatttttta 1740 gaattttttt agatggcggg ggggcggggg ggtggcggtg gtgagaaatt atagttttcg 1800 gtatgtaacg ttttaggggt ttattgtatt gaatgttggg ggtcgtagtt tttggttttt 1860 gaggattagt tgcgtagttt tggttttttt ttttacgttt ttttagcgtg tttttgttag 1920 agttttgttt tgcgttttag atgttatatt tcgttttgat tatagtagag atatgtgttt 1980 attttaggag tttttattgt atatagtttt tagaagcggg tttagaaagt ttttatgttt 2040 cgggtaaggt cgttcggttt tggggggtcg gtttgagttt gggggtttcg ttttcggttt 2100 aagagtacga gttttcgaat tcgtttataa gtgcgttatt tgggtattcg gagcgtttat 2160 tttttttgtg ttttttcgcg gtcggaattt ttaggttttt tttatttggt ttatagaaga 2220 acgtggttgg gattttttcg attattttag ggaaatcgcg agtagcgttg aggttttcga 2280 ttttttaata aagtataaag gcggcggtga tttgacggtc gtagaatttt ttttgtgaat 2340 taggtggaga gcgtggtcgt aaaagcgggt ttagtataga aaaggaaaat ttttagttta 2400 acgagtgtag gaggatgtat ttgtagatat ttgaaagtaa aatttgtggt gttgtatatg 2460 agaacgggat tgtagttttg taattttata gaaa 2494 <210> 383 <211> 2476 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 383 aattattagg aggttggggg aaaagagggg aaaaacgggt aaggaaggtt gtaaatgtta 60 agatgttaaa taggaattta atcgaagttc gaagtgaaat atagtttttt ttggtttaat 120 tgttatgtaa ataattttta agtattttta gatgtaaaga aaaatagtta ttgtgtatag 180 gcgttagttg aatgttcgag agttggatga atggggaaga tttgttatat atttagtggt 240 gggtggattt tattaggttg tagtttttat atagtttttt tttgttgtat tgtagaggcg 300 ttattttttt cgttttaatt tttatttaat tcgatttttt tatttgtatt ttaaaaaaaa 360 gatttttcgg atttttttta gtattttgtg tttttagggg aattaaatta gagtttttag 420 agttgttagg gaagaggtcg cgttttaatt agataaacgt ttttttggat gtataggata 480 gagttcgtgt ttttttatta ttcgttattg ttttttttag acgtatattt tatttttcgt 540 tttatttttt tttcgttaag gattttatag tttagtatag aattaagttt cggaggtgat 600 tcgagggtgg gaagtagagg ggtttcgagg tttcgttaga agtttcggta gcgtttttgt 660 ttttttttag gcggacgcgt agtttcggga agggagtcgg gcgggagttt cggtggcgta 720 ttgagattaa cgcggttcgg tttacggcga gggcggggtg tcgcggtttt tgttttcgcg 780 gattttttgt tttttagata gagtttaggg tgcgagcgaa ttttcgggac gtttagattt 840 ggggaaggcg cggggtggtt atgggttttc gatttttttt atttttcgta agttatataa 900 aagggagacg cggatatgta taaagtttgt ttgtggaagg cggtgcgcga tttcgacgtc 960 ggttcgggtt agggtcgtat ttaggttgtc gtcgttagta gtcgcgaaaa gaggttggag 1020 taaggaaggg ggatgggggt gagagaggaa ggtgaaacga ggcggagaac gtagggaaaa 1080 gcgaggggtt tttagttttt tgggttgttt cgattttttt tttttttttt tagggtttaa 1140 gagaaaggaa agggtaacga tttaagagcg aaggattggt tttagggacg ttgcgttttc 1200 ggtttttttt acgtgttttt tttttttttt tttttgtttg aatgtttttc gtttttttcg 1260 attttcgttt ttaaggtagg gattaagtcg gggtttgggt ttagggtcgt tttttatttt 1320 tttcgtttcg ggttggcgcg gaattaggga gattagcgtt tcgttcgttt ttttttagcg 1380 ggtcggagcg cgattttttg gggtagggtt gggtcgaaag cggggatgcg ttggacgttc 1440 gtaagcgggg gcggagagga gaggggtttt attgacggat tttcggtttt tttgtattaa 1500 agatttgggt taaggttttg gggggtatcg cgtttttatc gtgtagtttt ttttcgtttt 1560 tcgaggcgcg gtatttattt ttagcgttcg agtcgtttag gcggttagta ggagtagtgt 1620 taaatcgggt agtatcgcga ttttgcgcgg ggtatcgagt gcgttgttgt gcgagtggga 1680 ttcgtcgcgt ttttgttttg ttcgcgtcgt tatcgtcgtc gtttttcggg gttttcgcgt 1740 acgttttttc gcgtgttttc gtttatcgtt gtcgaggaaa ttgacggagt tcgagcgcgg 1800 cggcggggtt tagagttagg cgagttagtt gattcggttt atttcgttcg gtattcgaga 1860 gagattttta gcggcgtcgt cggggaattg cgttcgttcg cgtcgggagg ggttttcgcg 1920 tttcgcgttt ataggtgtac gcgtttttgg cgtcgtttgt attttacgcg tttttttcgt 1980 ttttcggtcg acggtttatt tgggtttcgt gaatagtggg agggagagtt tggggttagg 2040 agagggacgg tgtaggatta gggaaaggtg agttttagga cgttgaggtt ttagaaaagt 2100 cgagagcgtt tttgttcgtt ttcgtgagtt tgaattattc gatttcgtag gtttttcggg 2160 ggtgtcgtat aaaggattgt tgttagggtg cgtttttatt cgtatttcgt tttttttttc 2220 ggtttggaga ggtggggtag gcgtttttgg aagagaatga gaacgagtga agtttaaagg 2280 aaataggatt ttttttgttt gttgagatag taaaatttta ttttttaatt tttaacgtta 2340 aaagtaggta cgagtaattt ggaattttta tttttagaac gaattaaagg agtaaggcgt 2400 aggatttggt aaagaagcgg ttaatttatt tatttttttt tgaaagtagg gttttgggtt 2460 tgggttttgt tttttt 2476 <210> 384 <211> 2476 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 384 aaagaaataa aatttaagtt tagaattttg tttttaagaa gaagtaaatg ggttggtcgt 60 ttttttgtta ggttttgcgt tttgtttttt tggttcgttt taaagataga aattttaggt 120 tgttcgtgtt tgtttttgac gttgggggtt aaaaaatgag gttttgttgt tttaataagt 180 aaagaaaatt ttattttttt taagttttat tcgtttttat ttttttttag aaacgtttgt 240 tttatttttt taaatcgaga gaaaaaacga aatgcggata aaaacgtatt ttagtagtag 300 ttttttatac gatattttcg ggaggtttgc ggggtcggat gatttaagtt tacggggacg 360 agtaggagcg ttttcgattt ttttagagtt ttagcgtttt aggatttatt tttttttgat 420 tttgtatcgt tttttttttg gttttagatt ttttttttta ttgtttacga agtttaggtg 480 ggtcgtcggt cggggagcgg agggggcgcg tggggtgtag gcggcgttaa gggcgcgtgt 540 atttgtgggc gcggggcgcg agggtttttt tcggcgcgag cgggcgtagt ttttcggcgg 600 cgtcgttagg ggtttttttc gggtgtcgag cggggtgggt cggattagtt gattcgtttg 660 gttttgagtt tcgtcgtcgc gttcgggttt cgttagtttt ttcggtagcg gtaggcgaga 720 gtacgcggag gagcgtgcgc gggggtttcg ggagacggcg gcggtggcgg cgcgggtaga 780 gtaaggacgc ggcggatttt attcgtatag tagcgtattc ggtgtttcgc gtagggtcgc 840 gatgttgttc ggtttggtat tgtttttgtt ggtcgtttgg acggttcggg cgttggaggt 900 gggtgtcgcg tttcggaagg cggggggagg ttgtacggtg gggacgcgat attttttaag 960 attttaattt aagtttttaa tgtagagaag tcgggggttc gttaatggga tttttttttt 1020 tttcgttttc gtttgcggac gtttagcgta ttttcgtttt cggtttagtt ttgttttagg 1080 gagtcgcgtt tcggttcgtt gagagggagc gggcgaggcg ttggtttttt tggtttcgcg 1140 ttagttcggg gcgagaaggg tagggggcga ttttgagttt agatttcgat ttagtttttg 1200 ttttggaagc gggggtcggg ggaggcgaga gatatttaga taggggggaa gggggaagga 1260 gtacgtgggg aaaatcgaaa acgtagcgtt tttaaagtta gtttttcgtt tttgaatcgt 1320 tgtttttttt ttttttttgg gttttgggga ggaggaggag gagtcgggat agtttaggaa 1380 gttaggagtt tttcgttttt ttttgcgttt ttcgtttcgt tttatttttt ttttttattt 1440 ttattttttt tttttgtttt aatttttttt cgcggttgtt ggcggcggta gtttgggtgc 1500 gattttagtt cgagtcggcg tcggggtcgc gtatcgtttt ttataggtaa attttgtgta 1560 tgttcgcgtt ttttttttgt gtaatttgcg agaaatggga ggggtcggag atttatagtt 1620 atttcgcgtt ttttttaagt ttggacgttt cgggagttcg ttcgtatttt aagttttgtt 1680 tgagaggtag aaggttcgcg ggaataaaag tcgcgatatt tcgttttcgt cgtgggtcga 1740 gtcgcgttag ttttagtgcg ttatcgaggt tttcgttcgg tttttttttc ggggttgcgc 1800 gttcgtttgg gagggggtag agacgttgtc ggggtttttg gcggagtttc ggggtttttt 1860 tgttttttat tttcggatta ttttcgaggt ttaattttgt gttgggttgt aaagtttttg 1920 gcggggagga aataaggcgg agagtgggat gtgcgtttgg aaagggtagt ggcggatggt 1980 ggggaggtac gggttttgtt ttgtgtattt aaggaggcgt ttgtttgatt aaggcgcggt 2040 tttttttttg gtagttttgg ggattttggt ttagtttttt tgggggtata ggatgttggg 2100 gagggttcga agggtttttt ttttagggtg tagataaaag gatcgaattg agtgaagatt 2160 aagacggaga agatggcgtt tttgtagtgt agtaaagaaa agttgtgtgg aggttgtagt 2220 ttagtgaaat ttatttatta ttaggtgtat aataagtttt ttttatttat ttaattttcg 2280 aatatttagt taacgtttgt gtataatgat tgtttttttt tatatttgaa gatgtttaga 2340 agttgtttgt atgatagttg ggttagagga ggttgtattt tatttcggat ttcggttggg 2400 tttttgtttg gtattttaat atttgtaatt ttttttattc gttttttttt tttttttttt 2460 tagtttttta gtaatt 2476 <210> 385 <211> 6887 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 385 tgttgtttgt gggttgttgg ttggttgtag tttgttggtg atgagggtat tatagttgtt 60 ttgattgtgt agattatgta tgttttggtt ttgggaattt attatgtatt agaatatatt 120 agtgtttgta ttttaaaagg ttaaattatt ggtttttagt tagggatttt tggtaagtgg 180 tttgttagtg atgagtgttt gtttatattg gtatatagtg gagttttttg tttttggttt 240 atttgttttt aggaaagttt tggggtgagg tgaaggtgat tgaagtaatg tttttttttt 300 tagattgtag ttgtttaggg gggatatagt atggtatttt ttattgaatt ttttttgttt 360 gtttgtattt tagttttttt ttttttagtg atttttttat tttttttttt tttttttttt 420 ttgatgtttg attttagtag taaaggaggt aaaaaaggta ttgagttgtt agttaaattt 480 gaaaagtgtg gttttgtttt ttttatagtt attggtagtt ttttgtggaa ggtttgtttt 540 ttggggtagt tgtggttttg gagtggttgt gtttggtgtt tgttgggtgt ggttttgttt 600 taggtttggg agggtaggtt ggttgttttg gtgagtggta gagttttttt ggatagtttt 660 tgtttattta aatagaagat gttggtgttg gagtgggttt ggatatggtg aggttgtgag 720 ttggtttgag tggtggggtt tggtgatttt tttttttttt tttgtttttt tttttttttt 780 gtatgtatgt tttgtttgtt tttattttgt ttttattttg ggtgagtttg tttgtagttt 840 ggggtgtata tttgtatgtg tatttttttt tatttatttt tgtgtttgtt tttatttttg 900 tagttgagtt ttgttatgtg tgttttgttt gtttgttggt tgtttttgtt gtttttgttg 960 tttttgggtt ttgatggatt gaatgaaggt tgtttatatt gtttattgat gttttattaa 1020 agatttagaa ggttgtgtta tgaatttgga gttgataatg gaaagtttgg gtattttgta 1080 tgggttggtt ggtggtggta gtggtggggg tggtggtggg ggtggtgggg gtggtggtgg 1140 gggtttgggt tatgagtagg agttgttggt tagttttagt ttttattatg tgggttgtgg 1200 tgttgttggt ttgttgtggg gttttttgtt gtttttaatt gtgtattagg agttgggtat 1260 ggtggtagtg gtggtagtgg tggtgttgtg tttggttatg gttattagta tggttttgat 1320 tttggatggt ggtgattatt ggtttgagtt ttttattttg ttgtattatg ttatgagtat 1380 gttttgtgat ttgtttttgt ttggtatggg tatgagtaat atttatatta tgttgatatt 1440 gttttagttg ttgttattta tttttattgt gtttgataag ttttattatt tttatttgta 1500 ttattatttg tattattatt attattatta ttattagtgt ttgtttggta atgttagtgg 1560 tagttttatt tttatgtgtg atgagtgtgg gtttttggtt atgaataatt tttatagttt 1620 ttataaggag atgtttggta tgagttagag tttgtttttg ttggttgtta tgttgttggg 1680 taatgggtta ggtggttttt ataatgtgta gtagagtttg tttaattatg gtttgttggg 1740 ttatgataaa atgtttagtt ttaattttga tgtgtattat attgttatgt tgatttgtgg 1800 tgagtaatat ttgttttgtg gtttgggtat tttatttgtg gttatgatgt tgtatttgaa 1860 tggtttgtat tatttgggtt atatttagtt ttatgggttg gtgttggtat ttagttgtga 1920 gtggttattt ttgtttttat tgggtttgta ggtggttatg ttgggttagt tggaagaaat 1980 taatattaaa gaggtggttt agtgtattat agtggagttg aagtgttata gtatttttta 2040 ggtgattttt gtgtagaggg tgttgtgttg gttttagggg attttttttg atttgttttg 2100 gaatttaaaa ttgtggagta aatttaaatt tggtagggag attttttgta ggatgtggaa 2160 gtggttttag gagtttgagt tttagtgtat gtttgtttta tgtttggtag gtaaggttgg 2220 ggttagttag gggttaggtt gttgggaaga gggttttggg tttggtgttt gtggtttaag 2280 tttgtgtgtt gagttatttt ttttgatttt tttttttttt tttttatata tgtttttttt 2340 ttttttgttt ttattttttt ttttattttt tttttttttt ttgttttttt tttatttttt 2400 tttttttttt tttttttttt tttttatttt ttttttgttt ttgagttttt attgattgat 2460 ttttttttat tttatttgtt ttttttttaa tgtgttaatt tttgttttat ttttgatttt 2520 tttaggtatt gggaggtggg atgggggtgt gtgttttttt ttaggagttt tgttttttta 2580 agatttatag aaattaggat ttgtttttat ttaaaatttt atgtatttta agtttttttt 2640 agataatata ttttaatttt ttgggttgat tagttttttt gtgtagaggt agttgagagg 2700 ttttgttttg tagagggaaa agagtttttt atttttttat ttattatata ggtaaattta 2760 tttggttatt ggttgaaggt atagttttgt ttttgtgggg aattggtggt taggatataa 2820 tagtgttttt ggagtttatt tttggttttg gtgttggtgt agggattttt tgattgggtt 2880 tgaggggttt gggttagttt taatgttatt atttatagtg agggtagggt gtaaggttga 2940 gaaggttata tttattgttt tgggaggatg tgggagaaga gattgaggtg gaaagtgttt 3000 tgttttgttt attggttgtt tttgttttgg ttttagtgtt tgttgggatt tgttaggatt 3060 tgttggggtt ttgggagatt ttgagtattt gtaggaagag gtgttgagaa attaaaaatt 3120 taggttagtt aatgtatttt tgttgttggt tgtaggtttt gtttttgtat taagtgggtg 3180 ttgattgtgt gtgtttggtg attgtgggga ggattggtgg tttgtgggag gggatgggta 3240 gaggtgtggg ttatattgtt ttggagttgg tttggttttt tgtgtttttt ttagtggtta 3300 agttgtgagg tatagttttt tattgtttta ggagtataga aattttttgt gtgggtggtg 3360 ggtgtgtgag ttagagggaa agatgtagta gttattgtga ttggtatgta gttgtgtgtt 3420 tttgtgtgta tggattttgt gtggtgtgtg tggtgattgt gttgttttta ggagtaagtt 3480 atgggtttag aggggtaaaa tgtttaggtt ttttgttggg aaggatatat tatattttat 3540 ggtaagttag ggtgggtgat tttttatgga ttgggtggag gggggtattt tttaggattg 3600 gtgggtggtt taggggaata atttgtggtg gtgatgattt gtatagtgtg ggttttggga 3660 tgtgtgtggt tttgagttag ttttgtatag tttgtttttg gagttgtgag tttaggtttt 3720 tatttttgat tttttgggtt ttttttgtat tgttgagttt agtttgtggg gtgtatttga 3780 ttaatgtttg atagggttgg ggaatgtgat aggtagtagg tttatttggg tttggggagg 3840 gggagttttt gttttgatag tatttttttt tgttgtttgt tggtggattt ttatttttag 3900 ttggtaattg ttttgtagtg ttgatttaag aaggtaaaga aaattaggtt tttttgtaaa 3960 gagttttttt taaattggtg gattttggat attttgagtg gatttagaaa tttatgtaat 4020 tttttttttt tagtttattt tttatttttt tttatagttt tttttgattt gttgttggtt 4080 tggggtaaga taaagtagtt agtagagagt gataataata gtggtgggaa atgaattgga 4140 gattggttga tagtttttaa tattttgtta tagatttttt tgaatgtttt aggttgtttt 4200 tggtgggttt tagtatttgt tggttttttg ggtattgggg attagaagga atttggtagt 4260 tggttttagg ggtatagtta aaggtaggat gatagttatt tttttgttta ttttagagtg 4320 ttgttgtttt tttatgttgg ttgtgtaaag aatatagttt ttaaaaaata tgtgtttttt 4380 gtttatatag gtttgaaagt gatgaggaaa gtaatgtttt gtttattagt gagttttagt 4440 ttttaaaatg attttaagtg ttgttgagat gagaaagtgt ggtattttgg gggtttttag 4500 ttttatttgt gtttatggtg taagtttgta gggataggtt tgggatagta ttgtttatgt 4560 tgttagattt tttgtagagg attgttgaag ttgtttttgt gggagataga atgttttttt 4620 tagtgagtgg aaaaggtttg ttgaggattt tgttttgttt gagtatttaa atgtgtgttt 4680 gttttattat tttgggttga aaagggataa gagttttagt ttttttattt ggttatttta 4740 ttagtaatta taagtgtgtt gagtggttat tattatatag gaggtttttt agtttggggt 4800 tagtagatta gtttttttag atattgatgt agaagttggg attggtaagt aggtattatg 4860 tgtttggagt gttaggggat aggagtaaat ggagaagaaa agtggaggtt ttttttgttt 4920 ggagtattga ttggaatttt tgttggtatg ttgtagaggg tttttgttgt tgggttttgg 4980 gggtttaata agtttagttg ttttgtaggt ggtttggttg gatttttaga ttggtgtttg 5040 gaagatattg tttttgtttt ttttttgtta aatttgtttt tttttttttt tttataggtt 5100 ataggttttt tttttttttt attttggttt tgtttttggg ttttgttaaa tagttaagta 5160 ggttggggtt tagggggttt agaatgaaga ggtttgattt ggttagtgtt ggtaaagttt 5220 atttttaggt gaggttataa tagaggtagg ttttttttgt ttagtttgtt ggtgtagtta 5280 tagttaaggg tggtatttga aaggaaaagg gagaaaattt tggagaaatt tagattgttt 5340 taatgttaga ttttagagaa attgatttta aatgtatgga tttgtttgga aagggtggtt 5400 aagtggtagg tggttgtaat tttgtttggt tgggtttttg tagaggtttt ttaagattag 5460 tttttgtagg gtggttttta gtaatttgat aagaggtggt taagataaat ttttgtgggt 5520 ttgagtatat atttttgggt gttgggtttt agagattttt aaattaagta taaataagaa 5580 gggagtgaga gaatttaggt tagaatttgt atgggtattt tattgaggaa aagtgaggtt 5640 ttggtggtag gtatgttttt ttttgatgtt tgaaaattga gttgagtgtt tgattatatt 5700 tattgtagag gtttttgttt ttagtgagtt tggatttttt agtggtttgt ttggagttgg 5760 tttttagttt ttgttgtagt ttgatgtatg gttttttttt ggtagtaagt ttttagtggt 5820 tagtttgaag ttaattttgt ttaggtggtt gagggttttt agttaattta ttatgatgtt 5880 gtttgggtta tttgatgttt gtagtggtgg gatatggttt gggtagtgtg tagtggtttt 5940 tgttaggggt attgtgtgtg tgtttgtttt ttgttgtgtt ggggatgttt ttgggtgata 6000 tgggttgttg ggtatttttt aagttgagga aatggatttt ttttgtagag ttttgtgttt 6060 attttttaat tttttatttt gttttttgtt gttagggttt ttgatttagt ttattttttt 6120 tggtggttta gttagggatt agagttggag aggttgaatg taatttgtgt tagtatggaa 6180 tagatgatat gtttgtttgt tagttgtttg gatgaataat tgaaaagttt gttgtagttt 6240 gtgttttgtt aagttttggg tgttgggaga atattttttt aatatgtatt agggtgggtg 6300 ggagtgggta gaggaggtgg gatttgaggg aggagagtga atttgagtag gagaagtagt 6360 ttaggtagtt aggtgttttt gatgtgagag gttgggtatt tatttttatt ttaggttttt 6420 tattgtgtgg ttatgttatt tttttaaata aatgtgtata tggagggaga ttgatgttga 6480 taatgtttag aagattaaaa gagtattaat gttggtaata ataatgtaaa tgtgtggatt 6540 tagattttat tgatttggaa tttgatttgg tgtgttttta gtaagtttga tggtgtgttt 6600 tttttagtag agtgtttatt agtgttatgg ttttgtggtt ttttagtggt gttgttttgt 6660 tagttttgtg tgggtttttt tgtttgattg tagttttttt tttgtgaggt tttagtttgt 6720 tttatttttt tgaggttttt tttttttttt gtggggtttt ttgttttttg tatttttttt 6780 tttgattttt gtattatttg tttttgtgtg tatatattgt tatttgtgtt tttggtgatt 6840 tgtttgggtg gttgggtttg tgaagttaat gtgttgaatg gtgtttg 6887 <210> 386 <211> 6887 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 386 tgggtattgt ttagtgtatt ggttttgtgg atttagttgt ttaggtggat tgttggaagt 60 gtaagtagtg gtgtgtgtgt ataggggtgg gtggtgtaga ggttggggga gggggtgtag 120 agggtagaga gttttgtgag aggaggagaa aattttgggg aagtaaggtg ggttggggtt 180 ttgtggggga ggagttgtgg ttagatggga gaatttgtgt agagttggtg aagtggtatt 240 gttggaaaat tgtggggttg tggtgttggt gagtgttttg ttgggaagag tgtgttgttg 300 ggtttattgg aaatgtgttg gattaagttt tagattaatg aaatttgggt ttatatgttt 360 atgttattgt tgttagtatt aatgtttttt taatttttta aatattatta gtattgattt 420 ttttttatat atatatttgt ttgagaaagt gatataatta tatagtggaa agtttggaat 480 aaaaataaat gtttagtttt ttgtattgag ggtgtttggt tgtttgggtt gttttttttg 540 tttgggttta tttttttttt ttgggttttg ttttttttgt ttgtttttgt ttattttgat 600 gtgtgttggg aaggtgtttt tttggtattt gggatttgat gaagtataga ttgtagtgaa 660 ttttttaatt atttatttaa gtagttagta ggtaaatata ttgtttgttt tgtattggta 720 tgggttgtgt ttagtttttt tagttttgat ttttaattaa attgttagga gaggtgggtt 780 gagttgggag ttttagtagt gagaaatgag gtgggaggtt ggggggtggg tgtgagattt 840 tgtgaagggg gtttgttttt ttggtttggg aggtgtttag tggtttgtgt tatttaagga 900 tgtttttggt gtagtgggag ataagtatgt atgtggtgtt tttagtagga gttattgtgt 960 attgtttggg ttgtgttttg ttgttgtggg tattaggtgg tttaggtgat attatggtgg 1020 gttggttaag ggtttttggt tgtttgaata gaattggttt tagattggtt gttgggagtt 1080 tgttgttagg agagggttgt gtgttggatt atggtgggga ttggagatta gttttgggta 1140 ggttgttggg ggatttgggt ttattggagg tggaaatttt tgtagtaaat gtagttgggt 1200 gtttggtttg atttttgggt gttggaagaa aatatgtttg ttattgaggt tttgtttttt 1260 tttagtggga tgtttgtgta agttttagtt tgggtttttt tatttttttt ttgtttgtgt 1320 ttggtttaga ggtttttggg gtttaatgtt tgagagtgtg tgtttgaatt tgtagaaatt 1380 tgttttggtt gttttttgtt aggttgttga aaattgtttt gtaagggttg gttttgggga 1440 atttttgtga aggtttgatt gggtggggtt gtaattattt gttatttagt tgtttttttt 1500 gaatgaattt gtgtatttgg agttaatttt tttgaaattt aatgttgggg taatttaaat 1560 ttttttgaag tttttttttt ttttttttta agtgttattt ttggttgtga ttatattggt 1620 aggttgggta ggaaggattt gtttttgttg tgattttgtt taagggtgag ttttgttggt 1680 gttggttaaa ttagattttt ttattttgag ttttttaaat tttggtttgt ttggttgttt 1740 ggtaggattt gggggtgggg ttaaaatgag agagaaaggg aatttataat ttatgagaga 1800 aagagaagag gtaggtttgg tgggaggggg gtagggatgg tgttttttag gtattggttt 1860 gagagtttgg ttgagttgtt tgtggagtgg ttgggtttgt taaatttttg gggtttaatg 1920 gtgagggttt tttgtggtgt attggtgggg attttgattg atattttggg tggagaaagt 1980 ttttgttttt tttttttatt tgtttttgtt ttttagtgtt ttgagtatat aatatttatt 2040 tattagtttt agtttttgta ttagtgtttg aagagattga tttattgatt ttaaattgaa 2100 aagtttttta tgtaataata attatttaat atatttgtag ttgttgataa aatggttaga 2160 taaaaaggtt aaagtttttg ttttttttta atttagggta ataaaataga tatatatttg 2220 aatgtttgag taaagtgggg tttttagtag gtttttttta tttgttggag gaggtatttt 2280 gttttttatg aaggtagttt tagtgatttt ttgtggaaaa tttagtagtg tgggtagtgt 2340 tgttttgggt ttgtttttgt agatttgtat tatgggtgtg ggtggggttg aggatttttg 2400 ggatgttatg tttttttatt ttagtaatgt ttgggattat tttaaaagtt gaaatttgtt 2460 aataggtgaa gtattatttt ttttattatt tttagattta tatgggtaga aggtatgtgt 2520 tttttaaaag ttgtgttttt tgtgtgattg gtatgagggg gtggtagtgt tttgagatga 2580 gtaggagaat agttgttatt ttgtttttaa ttgtattttt aagattagtt gttaagtttt 2640 ttttggtttt tggtgtttaa gaagttggtg ggtattaaaa tttattagag atagtttggg 2700 atatttgggg ggatttatga taaaatgtta agaattgtta gttagttttt agtttatttt 2760 ttgttgttat tattattgtt ttttattggt tgttttattt tgttttgaat taatagtaaa 2820 ttagagaaaa ttgtaggaga ggatgaaaaa taaattaaag gagaaagatt atataaattt 2880 ttaaatttat ttaaagtatt tggagtttgt tgatttgggg gaggtttttt gtagggaaat 2940 ttagtttttt ttattttttt agattaatat tgtggggtga ttattgattg ggaataggaa 3000 tttattagta gatggtaaag gaaaatgttg ttaaagtgga aatttttttt ttttaagttt 3060 gggtgaattt gttgtttgtt atatttttta gttttgttgg gtgttggttg agtgtatttt 3120 ataagttggg tttagtggtg tgaggaaagt ttgggggatt gggggtggaa atttgagttt 3180 gtagttttgg aagtgagttg tgtgaggttg gtttggaatt gtgtgtattt taagatttgt 3240 gttatgtaaa ttattgttat tatgaattgt ttttttagat tgtttgttga ttttgaaaga 3300 tatttttttt tatttgattt atgggaagtt gtttattttg gtttgttata gggtatagtg 3360 tgtttttttt agtgggggat ttggatattt tgtttttttg ggtttgtggt ttgtttttag 3420 gggtagtgta gttgttatgt atattgtgtg gggtttgtgt gtataaaagt gtgtaattgt 3480 gtgttagttg tagtaattat tgtatttttt tttttagttt gtgtatttgt tgtttatata 3540 ggaggttttt gtgtttttag aataatagag ggttgtattt tgtagtttgg ttgttagagg 3600 aggtataaag agttgagttg gttttagaat aatgtaattt gtgtttttat ttgttttttt 3660 ttgtgggttg ttagtttttt ttgtggttgt taggtgtgta taattagtgt ttgtttaatg 3720 taaaggtgga gtttgtagtt ggtggtaggg atgtattaat taatttgaat ttttaatttt 3780 ttagtatttt tttttgtgag tgtttagggt tttttggagt tttggtaaat tttggtaaat 3840 tttagtaaat gttgggattg gggtaaggat ggttggtgag taaggtaaag tgttttttat 3900 tttagttttt ttttttatgt ttttttaaag tggtgaatgt gattttttta attttatatt 3960 ttgtttttgt tgtaggtagt gatattggag ttggtttgag ttttttaagt ttggttagaa 4020 agtttttgtg ttaatgttaa ggttagagat gggttttagg agtgttgttg tattttggtt 4080 gttggttttt tgtgggggta aggttgtgtt tttagttaat gattaaataa gtttgtttat 4140 atggtgggtg ggagagtaga gagttttttt ttttttgtag agtaaagttt tttaattgtt 4200 tttgtatagg gagattagtt agtttggaaa attgaaatgt gttgtttaaa agagatttga 4260 agtgtatggg gttttgaata agggtaggtt ttggtttttg tgggttttgg aaagataggg 4320 tttttagagg aaaatgtata tttttatttt gttttttagt atttgggaag attggaaata 4380 gggtaaaggt tggtatattg aggggagggt gaatgaaatg ggggggggtt ggttaatgaa 4440 agtttaggga taaggagaga gtaagaaaga aaaagaaaag ggagaaggga aagtagggga 4500 agagtggaag agaaagagaa aatggaagaa gaaataaaaa tgagaagaaa gaggatgtgt 4560 ataggaaaga gaaggaaaga attaagagaa gtgatttggt gtgtagattt gggttataag 4620 tattggattt ggagtttttt ttttagtagt ttggtttttg gttagttttg gttttatttg 4680 ttaggtgtaa ggtggatatg tgttggaatt tgggtttttg aagttatttt tatattttgt 4740 ggaaggtttt tttgttagat ttgagtttat tttatggttt tggattttgg agtaggttgg 4800 agagagtttt ttgagattgg tatagtattt tttgtgtaaa gattgtttgg gggatattgt 4860 agtgttttag ttttgttgtg atgtgttggg ttattttttt ggtgttgatt ttttttagtt 4920 ggtttgatgt ggttatttgt gagtttgatg aggatgaggg tggttgtttg tgattgggtg 4980 ttagtattgg tttgtgagat tgagtgtggt ttgggtggtg taggttgttt aggtgtgata 5040 ttatggttgt aggtggggtg tttaggttgt gggataggtg ttgtttattg tgggttagta 5100 tggtagtgtg gtgtgtgttg aagttggggt tgagtatttt gttgtggttt ggtggattgt 5160 agttgggtag attttgttgt gtgttgtgga ggttgtttag tttgttgttt agtggtgtgg 5220 tggttagtgg ggataggttt tggtttatgt tgggtatttt tttgtaggga ttgtagaggt 5280 tgtttatggt tgggagtttg tgtttgttgt gtatgagggt gaagttgttg ttgatgttgt 5340 tggataggtg ttggtggtgg tggtggtggt ggtggtgtgg atggtggtgt gggtgagggt 5400 ggtggaattt gttagatatg gtggagatgg gtggtagtgg ttggagtggt gttagtgtgg 5460 tgtaggtgtt gtttatgttt atgttaggtg gagatgagtt gtaggatatg tttatggtgt 5520 ggtgtagtgg gatggagagt ttgggttggt agttgttgtt gtttaggatt gaggttatgt 5580 tggtgattat ggttgagtgt gatgttgttg ttgttgttgt tgttgttgtg tttagttttt 5640 ggtgtgtggt tggaggtggt ggagggtttt gtagtgagtt agtggtgttg tggtttgtgt 5700 ggtgggggtt ggggttggtt agtagttttt gtttatggtt tgggtttttg ttgttgtttt 5760 tgttgttttt gttgttgttt ttgttattgt tgttgttggt tggtttgtgt aaagtgttta 5820 gattttttat tgttagtttt gggtttatgg tgtagttttt taggtttttg gtgaggtatt 5880 gataggtggt gtaggtagtt tttatttagt ttattagggt ttgggggtgg tgggggtggt 5940 gggggtggtt ggtgggtggg taaggtgtgt gtggtggggt ttggttgtgg gagtgggggt 6000 gggtgtggga gtgagtggag aggagtgtgt gtgtgggtgt gtgttttggg ttgtgggtgg 6060 gtttgtttgg ggtgggggtg gggtgggggt ggatggggtg tgtgtgtggg agaggggagg 6120 ggatggggag ggagggaggg attattgggt tttgttgttt gggttggttt gtagttttgt 6180 tatgtttgag tttgttttgg tgttgatgtt ttttgtttgg gtgagtggga gttgtttaga 6240 agggttttgt tgtttgttgg ggtagttaat ttattttttt ggatttgggg tggggttatg 6300 tttgatgggt gttaagtgta attattttga ggttgtagtt gttttgggag gtgggttttt 6360 tatgggaagt tattagtggt tgtggagggg gtggggttgt attttttagg tttggttgat 6420 ggtttggtgt tttttttatt ttttttgtta ttggaattaa atgttaagga gagggaggga 6480 ggagaaggtg ggggggttgt tggggagagg gaggttggag tgtgagtgag tgagagagat 6540 ttggtgaaag atgttgtgtt gtgttttttt tgagtagttg tgatttgggg gaaggggtat 6600 tgttttaatt gtttttgttt tattttaaag tttttttgga ggtgagtaag ttgggagtaa 6660 aagattttgt tatgtgttag tatagataaa tatttgttat taataagtta tttattgaga 6720 gtttttagtt gggagttaat agtttagttt tttaaaatgt aggtgttaat gtattttaat 6780 gtatggtaaa tttttgaggt tgggatatgt ataatttatg tggttagagt aattgtagtg 6840 tttttgttgt tagtgagttg tggttggttg gtggtttatg ggtggtg 6887 <210> 387 <211> 2494 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 387 tttttatgaa gttataaagt tgtaattttg tttttatgtg tagtattata ggttttgttt 60 ttaaatattt gtaggtgtat ttttttgtat ttgttaaatt aagggttttt tttttttgtg 120 ttagatttgt ttttatgatt atgtttttta tttgatttat agaaagggtt ttatgattgt 180 taggttattg ttgtttttgt attttattgg ggagttgaag gttttagtgt tgtttgtgat 240 ttttttaagg tggttgggaa ggttttaatt atgttttttt gtaaattaga taaggaaggt 300 ttggggattt tggttgtgga aaggtataga ggaggtgaat gttttggatg tttaagtgat 360 gtatttgtag gtggatttgg aaatttgtgt ttttgagttg gaggtggagt ttttagattt 420 agattgattt tttagaattg ggtggttttg tttgaggtat gaaggttttt taggtttgtt 480 tttaaaagtt gtgtataatg gagatttttg gaataggtat atatttttat tgtaattaga 540 atgagatgta atatttaaga tgtagggtag ggttttggta aagatatgtt gggggaatgt 600 gaaagaaagg gttaaaatta tgtagttggt ttttagagat taaagattat gatttttagt 660 atttaatgta gtgaattttt aggatgttgt atgttgggag ttgtagtttt ttattattgt 720 tatttttttg tttttttgtt atttgaaagg gttttagggg atttgtaatt ttttttgtgt 780 gttttttttt tttgagaagt gttgttatat gagaaagttg gttgtgaaag ttgtgttgga 840 attattttta atgaaatttt aggtatagat gggaaagggt gaagaatatg ttgttatggt 900 tattgttttt ttggttatgg aataaatgtt ttttaggatt tggaagtagt tttgttgtga 960 tttttttaaa aggatggatg tgttttttgt ttatatttat tggatgtttt tttttagagg 1020 ttaaggttgt ttaggtaaag gggtggtttt atgtgtgagg ggtttgtgga gttatttgat 1080 tggagaaaag ttgtaaattt tgattaattg gaaggagtta tgttttgggt attggttatt 1140 gtatttggat agttttgatt ggtggatttt tgtttttttt atgaattttt attgggtgtt 1200 gtgggtgtgt ggtgtggtgt gattggtggg tttatgtttt ttgttttttg tttgtgagaa 1260 gtgggggtga aaagtggttt gatttgtttg gggtgtagtg ggtggattgt gtggttggag 1320 gtgtgaggat ttgaatttag gggtggaggt ggtttttgtg attgaagggg atttgagatt 1380 tattggttgt atgttatgag ggttttgtgg gtgttgggtt tttgttgtgt tttgttgatt 1440 tttggtgagt gattttggag gagtagatgt ttttttttta tatatgtggt tgttttttga 1500 aggttttggg ggtgttgaat gtgggagggg ggattttggg gtttgtggtg ggttaaggga 1560 tgttattatt ttttgaaaga gggtaaggga attatgttta tttttttttt tttttggaaa 1620 taaaaaaaga gagtaatatt atttaattgt tttatagatt taatagtatt ttgtttggag 1680 gttttagtga ttttggggtg gggttttttt gaggttttgg tttttttggg agttgtgtga 1740 gttttttttt tttttttgtt tggaggattt ttttggttat tgtaattttt ggttatttta 1800 gtttttttgt tttttaattt tttagatttt gattttttgt aagtttgtgt ttttttttag 1860 atgttggttt tgggagtgtg aggtttgggg ttagtggaat ggtagtgtta gtgtgtttga 1920 tttagttttg ttggagtttg gtttttaata tttttttttt tttttatgtt tttgggttta 1980 attttagttt tttttgttag aggttgtata aattttattt gtattttgat ttgtgttaat 2040 gaaggttgaa gttttggttt gattagttgg gaggttttgg tttggtttgt gtgtaatatg 2100 tgtgggtgta gaagaggttt ggtattagtt tgtttaatgt tatttataaa tgattggaga 2160 tatattgttt agaagtggtg attgtttttg tattttagga tttattggag attttagtat 2220 ttgaatttaa atagatgttt tgttttggtt ttatttttgg tatttaaatt agggaatgta 2280 tttttttatt tttatttttt ttagttatta attgaatttt gtaattttta ttttttttta 2340 tttgattatt ttttttggag aagtgtgatg ttgaagagtt tgtttgtgtt aaatttttag 2400 ggttggttag agttgatgat gaagttgatg tggatggtat agtagaagag gatttgggta 2460 aaagtagaga aggattaagg atggatgatg aagt 2494 <210> 388 <211> 2494 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 388 attttattat ttgtttttga ttttttttta tttttattta gatttttttt tattgtatta 60 tttatattaa ttttattgtt agttttgatt gattttgaag atttaatatg ggtaaatttt 120 ttaatattat atttttttaa ggaggatgat taaataggga agggtagggg ttgtaaaatt 180 tagttggtaa ttaagggagg tggggatgaa agagtgtatt ttttggttta aatattaaag 240 gtaaagttaa gatagaatat ttatttaagt ttagatgttg aggtttttag tagattttga 300 aatatggagg tagttattat ttttaaatag tgtgtttttg attatttata aataatgtta 360 agtagattga tattaggttt tttttatatt tatatgtgtt gtgtgtaggt tgagttaagg 420 ttttttaatt gattaagtta aaattttggt ttttgttagt ataggttaga atgtaaatag 480 gatttatgta atttttggtg aggggaattg aaattgagtt tagaggtatg agaaggggga 540 gaaatgttaa gaattgaatt ttagtaaaat tgaattaaat atgttgatat tgttattttg 600 ttggttttag gttttatgtt tttgaggtta gtatttaaga agggatatgg gtttgtgagg 660 agttggagtt tggggaatta ggggatggga aagttgggat ggttgaaggt tgtggtggtt 720 gaaaaagttt tttgggtggg gaggggggag gggtttgtat agtttttggg ggagttagag 780 ttttagagag gttttatttt gaggttgttg agatttttgg gtgagatatt attagatttg 840 tagggtagtt agatgatgtt gttttttttt tttattttta gaggaagaag agaataaatg 900 taattttttt gttttttttt gaggaatggt gatgtttttt ggtttattgt aggttttggg 960 attttttttt ttatgtttaa tgtttttagg atttttgaga agtggttgtg tgtgtggagg 1020 ggggatgttt gtttttttag aattatttat tgaaggttag taggatgtag tagaggttta 1080 gtatttatag ggtttttatg gtgtgtggtt ggtgagtttt aagttttttt tgattgtagg 1140 agttgttttt atttttgggt ttggattttt atatttttag ttgtgtggtt tgtttattat 1200 attttaagta ggttgggttg ttttttattt ttattttttg tgggtggggg atgggaaata 1260 tgaatttatt aattgtgttg tattatgtat ttatggtatt taatgaggat ttgtgagggg 1320 ggtggaagtt tattaattgg agttgtttag gtgtggtgat tgatgtttga agtgtggttt 1380 tttttgattg gttagggttt gtagtttttt tttaattaaa tggttttgtg ggttttttat 1440 atgtgggatt gtttttttgt ttgggtggtt ttggttttta agggaaaatg tttaatgaat 1500 gtaagtagag aatatattta tttttttaga gaggttgtgg tggaattatt tttggatttt 1560 agagagtgtt tattttgtga ttggggaaat ggtagttatg gtaatgtgtt ttttattttt 1620 ttttatttat gtttggggtt ttgttggaag tgattttagt atgatttttg tggttagttt 1680 ttttgtgtgg tggtgttttt tggaaagaag aaatatatga gagaggttgt aaatttttta 1740 gaattttttt agatggtggg ggggtggggg ggtggtggtg gtgagaaatt atagtttttg 1800 gtatgtaatg ttttaggggt ttattgtatt gaatgttggg ggttgtagtt tttggttttt 1860 gaggattagt tgtgtagttt tggttttttt ttttatgttt ttttagtgtg tttttgttag 1920 agttttgttt tgtgttttag atgttatatt ttgttttgat tatagtagag atatgtgttt 1980 attttaggag tttttattgt atatagtttt tagaagtggg tttagaaagt ttttatgttt 2040 tgggtaaggt tgtttggttt tggggggttg gtttgagttt gggggttttg tttttggttt 2100 aagagtatga gtttttgaat ttgtttataa gtgtgttatt tgggtatttg gagtgtttat 2160 tttttttgtg tttttttgtg gttggaattt ttaggttttt tttatttggt ttatagaaga 2220 atgtggttgg gatttttttg attattttag ggaaattgtg agtagtgttg aggtttttga 2280 ttttttaata aagtataaag gtggtggtga tttgatggtt gtagaatttt ttttgtgaat 2340 taggtggaga gtgtggttgt aaaagtgggt ttagtataga aaaggaaaat ttttagttta 2400 atgagtgtag gaggatgtat ttgtagatat ttgaaagtaa aatttgtggt gttgtatatg 2460 agaatgggat tgtagttttg taattttata gaaa 2494 <210> 389 <211> 2476 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 389 aattattagg aggttggggg aaaagagggg aaaaatgggt aaggaaggtt gtaaatgtta 60 agatgttaaa taggaattta attgaagttt gaagtgaaat atagtttttt ttggtttaat 120 tgttatgtaa ataattttta agtattttta gatgtaaaga aaaatagtta ttgtgtatag 180 gtgttagttg aatgtttgag agttggatga atggggaaga tttgttatat atttagtggt 240 gggtggattt tattaggttg tagtttttat atagtttttt tttgttgtat tgtagaggtg 300 ttattttttt tgttttaatt tttatttaat ttgatttttt tatttgtatt ttaaaaaaaa 360 gattttttgg atttttttta gtattttgtg tttttagggg aattaaatta gagtttttag 420 agttgttagg gaagaggttg tgttttaatt agataaatgt ttttttggat gtataggata 480 gagtttgtgt ttttttatta tttgttattg ttttttttag atgtatattt tattttttgt 540 tttatttttt ttttgttaag gattttatag tttagtatag aattaagttt tggaggtgat 600 ttgagggtgg gaagtagagg ggttttgagg ttttgttaga agttttggta gtgtttttgt 660 ttttttttag gtggatgtgt agttttggga agggagttgg gtgggagttt tggtggtgta 720 ttgagattaa tgtggtttgg tttatggtga gggtggggtg ttgtggtttt tgtttttgtg 780 gattttttgt tttttagata gagtttaggg tgtgagtgaa tttttgggat gtttagattt 840 ggggaaggtg tggggtggtt atgggttttt gatttttttt attttttgta agttatataa 900 aagggagatg tggatatgta taaagtttgt ttgtggaagg tggtgtgtga ttttgatgtt 960 ggtttgggtt agggttgtat ttaggttgtt gttgttagta gttgtgaaaa gaggttggag 1020 taaggaaggg ggatgggggt gagagaggaa ggtgaaatga ggtggagaat gtagggaaaa 1080 gtgaggggtt tttagttttt tgggttgttt tgattttttt tttttttttt tagggtttaa 1140 gagaaaggaa agggtaatga tttaagagtg aaggattggt tttagggatg ttgtgttttt 1200 ggtttttttt atgtgttttt tttttttttt tttttgtttg aatgtttttt gttttttttg 1260 atttttgttt ttaaggtagg gattaagttg gggtttgggt ttagggttgt tttttatttt 1320 ttttgttttg ggttggtgtg gaattaggga gattagtgtt ttgtttgttt ttttttagtg 1380 ggttggagtg tgattttttg gggtagggtt gggttgaaag tggggatgtg ttggatgttt 1440 gtaagtgggg gtggagagga gaggggtttt attgatggat ttttggtttt tttgtattaa 1500 agatttgggt taaggttttg gggggtattg tgtttttatt gtgtagtttt tttttgtttt 1560 ttgaggtgtg gtatttattt ttagtgtttg agttgtttag gtggttagta ggagtagtgt 1620 taaattgggt agtattgtga ttttgtgtgg ggtattgagt gtgttgttgt gtgagtggga 1680 tttgttgtgt ttttgttttg tttgtgttgt tattgttgtt gttttttggg gtttttgtgt 1740 atgttttttt gtgtgttttt gtttattgtt gttgaggaaa ttgatggagt ttgagtgtgg 1800 tggtggggtt tagagttagg tgagttagtt gatttggttt attttgtttg gtatttgaga 1860 gagattttta gtggtgttgt tggggaattg tgtttgtttg tgttgggagg ggtttttgtg 1920 ttttgtgttt ataggtgtat gtgtttttgg tgttgtttgt attttatgtg ttttttttgt 1980 tttttggttg atggtttatt tgggttttgt gaatagtggg agggagagtt tggggttagg 2040 agagggatgg tgtaggatta gggaaaggtg agttttagga tgttgaggtt ttagaaaagt 2100 tgagagtgtt tttgtttgtt tttgtgagtt tgaattattt gattttgtag gttttttggg 2160 ggtgttgtat aaaggattgt tgttagggtg tgtttttatt tgtattttgt tttttttttt 2220 ggtttggaga ggtggggtag gtgtttttgg aagagaatga gaatgagtga agtttaaagg 2280 aaataggatt ttttttgttt gttgagatag taaaatttta ttttttaatt tttaatgtta 2340 aaagtaggta tgagtaattt ggaattttta tttttagaat gaattaaagg agtaaggtgt 2400 aggatttggt aaagaagtgg ttaatttatt tatttttttt tgaaagtagg gttttgggtt 2460 tgggttttgt tttttt 2476 <210> 390 <211> 2476 <212> DNA <213> Artificial Sequence <220> <223> chemically treated genomic DNA (Homo sapiens) <400> 390 aaagaaataa aatttaagtt tagaattttg tttttaagaa gaagtaaatg ggttggttgt 60 ttttttgtta ggttttgtgt tttgtttttt tggtttgttt taaagataga aattttaggt 120 tgtttgtgtt tgtttttgat gttgggggtt aaaaaatgag gttttgttgt tttaataagt 180 aaagaaaatt ttattttttt taagttttat ttgtttttat ttttttttag aaatgtttgt 240 tttatttttt taaattgaga gaaaaaatga aatgtggata aaaatgtatt ttagtagtag 300 ttttttatat gatatttttg ggaggtttgt ggggttggat gatttaagtt tatggggatg 360 agtaggagtg tttttgattt ttttagagtt ttagtgtttt aggatttatt tttttttgat 420 tttgtattgt tttttttttg gttttagatt ttttttttta ttgtttatga agtttaggtg 480 ggttgttggt tggggagtgg agggggtgtg tggggtgtag gtggtgttaa gggtgtgtgt 540 atttgtgggt gtggggtgtg agggtttttt ttggtgtgag tgggtgtagt tttttggtgg 600 tgttgttagg ggtttttttt gggtgttgag tggggtgggt tggattagtt gatttgtttg 660 gttttgagtt ttgttgttgt gtttgggttt tgttagtttt tttggtagtg gtaggtgaga 720 gtatgtggag gagtgtgtgt gggggttttg ggagatggtg gtggtggtgg tgtgggtaga 780 gtaaggatgt ggtggatttt atttgtatag tagtgtattt ggtgttttgt gtagggttgt 840 gatgttgttt ggtttggtat tgtttttgtt ggttgtttgg atggtttggg tgttggaggt 900 gggtgttgtg ttttggaagg tggggggagg ttgtatggtg gggatgtgat attttttaag 960 attttaattt aagtttttaa tgtagagaag ttgggggttt gttaatggga tttttttttt 1020 ttttgttttt gtttgtggat gtttagtgta tttttgtttt tggtttagtt ttgttttagg 1080 gagttgtgtt ttggtttgtt gagagggagt gggtgaggtg ttggtttttt tggttttgtg 1140 ttagtttggg gtgagaaggg tagggggtga ttttgagttt agattttgat ttagtttttg 1200 ttttggaagt gggggttggg ggaggtgaga gatatttaga taggggggaa gggggaagga 1260 gtatgtgggg aaaattgaaa atgtagtgtt tttaaagtta gttttttgtt tttgaattgt 1320 tgtttttttt ttttttttgg gttttgggga ggaggaggag gagttgggat agtttaggaa 1380 gttaggagtt ttttgttttt ttttgtgttt tttgttttgt tttatttttt ttttttattt 1440 ttattttttt tttttgtttt aatttttttt tgtggttgtt ggtggtggta gtttgggtgt 1500 gattttagtt tgagttggtg ttggggttgt gtattgtttt ttataggtaa attttgtgta 1560 tgtttgtgtt ttttttttgt gtaatttgtg agaaatggga ggggttggag atttatagtt 1620 attttgtgtt ttttttaagt ttggatgttt tgggagtttg tttgtatttt aagttttgtt 1680 tgagaggtag aaggtttgtg ggaataaaag ttgtgatatt ttgtttttgt tgtgggttga 1740 gttgtgttag ttttagtgtg ttattgaggt ttttgtttgg tttttttttt ggggttgtgt 1800 gtttgtttgg gagggggtag agatgttgtt ggggtttttg gtggagtttt ggggtttttt 1860 tgttttttat ttttggatta tttttgaggt ttaattttgt gttgggttgt aaagtttttg 1920 gtggggagga aataaggtgg agagtgggat gtgtgtttgg aaagggtagt ggtggatggt 1980 ggggaggtat gggttttgtt ttgtgtattt aaggaggtgt ttgtttgatt aaggtgtggt 2040 tttttttttg gtagttttgg ggattttggt ttagtttttt tgggggtata ggatgttggg 2100 gagggtttga agggtttttt ttttagggtg tagataaaag gattgaattg agtgaagatt 2160 aagatggaga agatggtgtt tttgtagtgt agtaaagaaa agttgtgtgg aggttgtagt 2220 ttagtgaaat ttatttatta ttaggtgtat aataagtttt ttttatttat ttaatttttg 2280 aatatttagt taatgtttgt gtataatgat tgtttttttt tatatttgaa gatgtttaga 2340 agttgtttgt atgatagttg ggttagagga ggttgtattt tattttggat tttggttggg 2400 tttttgtttg gtattttaat atttgtaatt ttttttattt gttttttttt tttttttttt 2460 tagtttttta gtaatt 2476

Claims (31)

  1. 환자로부터 단리된 생물학적 샘플에서 모든 전사 변이형을 포함하는 셉틴(Septin) 9, FOXL2, SARM1, VTN, PRDM6, NR2E1, FAT 및 서열 번호:160 내지 서열 번호:165로 이루어진 군으로부터 선택되는 하나 이상의 유전자 또는 게놈 서열의 발현 수준을 결정함을 포함하되, 저발현(underexpression) 및/또는 CpG 메틸화가 세포 증식 질환의 존재 또는 상기 질환의 부류의 지표인,
    상기 환자에서 상기 세포 증식 질환을 검출 및/또는 분류하는 방법.
  2. 제 1 항에 있어서,
    종양성(neoplastic) 세포 증식 질환을 양성 세포 증식 질환으로부터 구분하고,
    상기 방법이, 저발현 및/또는 CpG 메틸화의 존재가 종양성 세포 증식 질환의 존재의 지표이고, 그의 부재가 양성 세포 증식 질환의 존재의 지표임을 그 특징으로 하는 방법.
  3. 제 1 항에 있어서,
    상기 세포 증식 질환이 암인 방법.
  4. 제 3 항에 있어서,
    상기 세포 증식 질환이 간세포 암종 또는 직장결장 암종인 방법.
  5. 제 1 항 내지 제 4 항중 어느 한 항에 있어서,
    상기 유전자로부터 전사된 mRNA의 존재, 부재 또는 수준을 검출함으로써 상기 발현 수준을 결정하는 방법.
  6. 제 1 항 내지 제 4 항중 어느 한 항에 있어서,
    상기 유전자 또는 그의 서열에 의해 코딩되는 폴리펩타이드의 존재, 부재 또는 수준을 검출함으로써 상기 발현 수준을 결정하는 방법.
  7. 제 6 항에 있어서,
    웨스턴 블롯 분석, 크로마토그래피, 면역 분석법, ELISA 면역 분석법, 방사성 면역 분석법, 항체 및 이들의 조합을 포함하는 군으로부터 선택되는 하나 이상의 수단에 의해 상기 폴리펩타이드를 검출하는 방법.
  8. 제 1 항 내지 제 4 항중 어느 한 항에 있어서,
    상기 유전자 내에서의 CpG 메틸화의 존재 또는 부재를 검출함으로써 상기 발현을 결정하고, 상기 메틸화의 존재가 세포 증식 질환의 존재를 나타내는 방법.
  9. 환자로부터 수득된 생물학적 샘플로부터 단리된 게놈 DNA를, 게놈 DNA의 하 나 이상의 표적 영역 내에서 메틸화된 CpG 다이뉴클레오타이드와 메틸화되지 않은 CpG 다이뉴클레오타이드를 구분할 수 있는 하나 이상의 시약 또는 일련의 시약과 접촉시킴으로써, 세포 증식 질환을 적어도 부분적으로 검출 및/또는 분류함을 포함하되,
    상기 표적 영역이 각각 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167로 이루어진 군으로부터 선택되는 하나 이상의 서열의 16개 이상의 연속적인 뉴클레오타이드의 서열을 포함하거나 엄격한 조건하에서 상기 서열과 하이브리드 형성하며,
    상기 연속적인 뉴클레오타이드가 하나 이상의 CpG 다이뉴클레오타이드 서열을 포함하는,
    상기 환자에서 세포 증식 질환을 검출 및/또는 분류하는 방법.
  10. a. 환자로부터 수득된 생물학적 샘플로부터 게놈 DNA를 추출하거나 다른 방식으로 단리하고;
    b. 5-위치에서 메틸화되지 않은 시토신 염기를 우라실 또는 하이브리드 형성 특성 면에서 시토신과 검출가능하게 상이한 다른 염기로 전환시키는 하나 이상의 시약으로 a)의 게놈 DNA 또는 그의 단편을 처리하며;
    c. 증폭 효소 및 서열 번호:10 내지 서열 번호:15, 서열 번호:28 내지 서열 번호:33, 서열 번호:30 내지 서열 번호:31, 서열 번호:42 내지 서열 번호:43, 서열 번호:38 내지 서열 번호:39, 서열 번호:50 내지 서열 번호:51, 서열 번호:168 내지 서열 번호:203, 및 이들의 보체로 이루어진 군으로부터 선택되는 서열에 상보적이거나 또는 적당히 엄격하거나 엄격한 조건하에서 상기 서열과 하이브리드 형성하는 뉴클레오타이드 9개 이상의 연속적인 서열을 포함하는 하나 이상의 프라이머와 처리된 게놈 DNA 또는 처리된 그의 단편을 접촉시키되, 처리된 게놈 DNA 또는 그의 단편을 증폭시켜 하나 이상의 증폭물을 생성시키거나 증폭시키지 않으며;
    d. 상기 증폭물의 존재 또는 부재 또는 그의 특성에 기초하여, 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167로 이루어진 군으로부터 선택되는 서열의 하나 이상의 CpG 다이뉴클레오타이드의 메틸화 상태 또는 수준, 또는 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167로 이루어진 군으로부터 선택되는 서열의 복수개의 CpG 다이뉴클레오타이드의 평균 메틸화 상태 또는 수준을 반영하는 값 또는 평균을 결정함으로써, 세포 증식 질환의 검출 및 분류중 하나 이상이 적어도 부분적으로 이루어짐
    을 포함하는, 세포 증식 질환을 검출 및/또는 분류하는 방법.
  11. 제 9 항에 있어서,
    상기 b)의 게놈 DNA 또는 그의 단편의 처리가 바이설파이트, 아황산수소, 다이설파이트 및 이들의 조합을 포함하는 군으로부터 선택되는 시약의 사용을 포함하는 방법.
  12. 제 9 항에 있어서,
    상기 c)의 접촉 또는 증폭이 증폭 효소로서 내열성 DNA 폴리머라제의 사용; 5'-3' 엑소뉴클레아제 활성을 갖지 않는 폴리머라제의 사용; 폴리머라제 연쇄 반응(PCR)의 이용; 검출가능한 라벨을 갖는 증폭물 핵산 분자의 생성을 포함하는 군으로부터 선택되는 하나 이상의 방법의 사용을 포함하는 방법.
  13. 제 1 항 내지 제 11 항중 어느 한 항에 있어서,
    상기 환자로부터 수득된 생물학적 샘플이 세포주, 조직학적 슬라이드, 생검체, 파라핀-매립된 조직, 신체 유체, 대변, 결장 유출물, 소변, 혈장, 혈청, 전혈, 단리된 혈액 세포, 혈액으로부터 단리된 세포 및 이들의 조합을 포함하는 군으로부터 선택되는 방법.
  14. 제 10 항에 있어서,
    상기 단계 d)에서, 각각의 경우 서열 번호:10 내지 서열 번호:15, 서열 번호:28 내지 서열 번호:33, 서열 번호:30 내지 서열 번호:31, 서열 번호:42 내지 서열 번호:43, 서열 번호:38 내지 서열 번호:39, 서열 번호:50 내지 서열 번호:51, 서열 번호:168 내지 서열 번호:203 및 이들의 보체로 이루어진 군으로부터 선택되는 서열에 상보적이거나 또는 적당히 엄격하거나 엄격한 조건하에서 이들 서열과 하이브리드 형성하는 뉴클레오타이드 9개 이상의 길이를 갖는 연속적인 서열을 포 함하는 하나 이상의 핵산 분자 또는 펩타이드 핵산 분자의 사용을 추가로 포함하고, 이 때 상기 핵산 분자 또는 펩타이드 핵산 분자가 그와 하이브리드 형성하는 핵산의 증폭을 억제하는 방법.
  15. 제 10 항에 있어서,
    상기 d)에서의 결정이 각각의 경우 서열 번호:10 내지 서열 번호:15, 서열 번호:28 내지 서열 번호:33, 서열 번호:30 내지 서열 번호:31, 서열 번호:42 내지 서열 번호:43, 서열 번호:38 내지 서열 번호:39, 서열 번호:50 내지 서열 번호:51, 서열 번호:168 내지 서열 번호:203 및 이들의 보체로 이루어진 군으로부터 선택되는 서열에 상보적이거나 또는 적당히 엄격하거나 엄격한 조건하에서 상기 서열과 하이브리드 형성하는 뉴클레오타이드 9개 이상의 길이를 갖는 연속적인 서열을 포함하는 하나 이상의 핵산 분자 또는 펩타이드 핵산 분자의 하이브리드 형성을 포함하는 방법.
  16. 제 15 항에 있어서,
    상기 하나 이상의 하이브리드 형성 핵산 분자 또는 펩타이드 핵산 분자가 고상에 결합되는 방법.
  17. 제 15 항에 있어서,
    상기 하나 이상의 하이브리드 형성된 핵산 분자를 하나 이상의 뉴클레오타이 드 염기에 의해 연장시킴을 추가로 포함하는 방법.
  18. 제 10 항에 있어서,
    상기 d)에서의 결정이 증폭물의 서열 결정을 포함하는 방법.
  19. 제 10 항에 있어서,
    상기 c)에서의 접촉 또는 증폭이 메틸화-특이적 프라이머의 사용을 포함하는 방법.
  20. a. 환자로부터 수득된 생물학적 샘플로부터 게놈 DNA를 추출하거나 또는 다른 방식으로 단리하고;
    b. a)의 게놈 DNA 또는 그의 단편을 하나 이상의 메틸화 민감성 제한 효소로 소화시키고, b)의 DNA 제한 효소 소화물을, 증폭 효소 및 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167로부터 선택되는 서열의 하나 이상의 CpG 다이뉴클레오타이드를 포함하는 서열의 증폭에 적합한 둘 이상의 프라이머와 접촉시키며;
    c. 증폭물의 존재 또는 부재에 기초하여, 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167로 이루어진 군으로부터 선택되는 서열의 하나 이상의 CpG 다이뉴클레오타이드의 메틸화 상태 또는 수준을 결정함으로써, 세포 증식 질환의 검출 및 분류중 하나 이상이 적어도 부분적 으로 이루어짐
    을 포함하는, 세포 증식 질환을 검출 및/또는 분류하는 방법.
  21. 제 20 항에 있어서,
    상기 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167로부터 선택되는 서열의 염기 16개 이상의 길이를 갖는 구획과 동일하거나, 그에 상보적이거나, 또는 엄격하거나 매우 엄격한 조건하에서 상기 구획과 하이브리드 형성하는 하나 이상의 핵산 또는 펩타이드 핵산과 하이브리드 형성시킴으로써 증폭물의 존재 또는 부재를 결정하는 방법.
  22. 게놈 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167로부터 유도되는 처리된 핵산으로서,
    상기 처리가 게놈 DNA 서열의 하나 이상의 메틸화되지 않은 시토신 염기를 우라실 또는 하이브리드 형성 면에서 시토신과 검출가능하게 상이한 다른 염기로 전환시키는데 적합한 것인,
    처리된 핵산.
  23. 서열 번호:10 내지 서열 번호:15, 서열 번호:28 내지 서열 번호:33, 서열 번호:30 내지 서열 번호:31, 서열 번호:42 내지 서열 번호:43, 서열 번호:38 내지 서열 번호:39, 서열 번호:50 내지 서열 번호:51, 서열 번호:168 내지 서열 번호:203 및 이들에 상보적인 서열로 이루어진 군으로부터 선택되는 처리된 게놈 DNA 서열의 16개 이상의 연속적인 뉴클레오타이드를 포함하는 핵산으로서,
    상기 처리가 게놈 DNA 서열의 하나 이상의 메틸화되지 않은 시토신 염기를 우라실 또는 하이브리드 형성 면에서 시토신과 검출가능하게 상이한 다른 염기로 전환시키는데 적합한 것인,
    핵산.
  24. 서열 번호:10 내지 서열 번호:15, 서열 번호:28 내지 서열 번호:33, 서열 번호:30 내지 서열 번호:31, 서열 번호:42 내지 서열 번호:43, 서열 번호:38 내지 서열 번호:39, 서열 번호:50 내지 서열 번호:51, 서열 번호:168 내지 서열 번호:203 및 이들에 상보적인 서열로 이루어진 군으로부터 선택되는 DNA 서열의 50개 이상의 연속적인 뉴클레오타이드를 포함하는 핵산.
  25. 제 22 항 내지 제 24 항중 어느 한 항에 있어서,
    상기 연속적인 염기 서열이 하나 이상의 CpG, TpG 또는 CpA 다이뉴클레오타이드 서열을 포함하는 핵산.
  26. 진단 수단으로서의, 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167, 서열 번호:10 내지 서열 번호:15, 서열 번호:28 내지 서열 번호:33, 서열 번호:30 내지 서열 번호:31, 서열 번호:42 내지 서열 번호:43, 서열 번호:38 내지 서열 번호:39, 서열 번호:50 내지 서열 번호:51, 서열 번호:168 내지 서열 번호:203 및 이들에 상보적인 서열로 이루어진 군으로부터 선택되는 핵산 서열의 16개 이상의 연속적인 뉴클레오타이드를 포함하는 핵산.
  27. (a) 엄격하거나 적당히 엄격한 조건하에서 모든 전사 변이형을 포함하는 셉틴 9, FOXL2, SARM1, VTN, PRDM6, NR2E1, FAT 및 서열 번호:160 내지 서열 번호:165로 이루어진 군으로부터 선택되는 하나 이상의 유전자 또는 게놈 서열의 전사 생성물과 하이브리드 형성할 수 있는 복수개의 올리고뉴클레오타이드 또는 폴리뉴클레오타이드;
    (b) 엄격하거나 적당히 엄격한 조건하에서 전사 생성물과 하이브리드 형성할 수 있는 올리고뉴클레오타이드 또는 폴리뉴클레오타이드, 및 전사 생성물을 포함하는 환자의 생물학적 샘플을 함유하는데 적합한 용기;
    (c) (b)의 하이브리드 형성을 검출하는 수단; 및
    임의적으로, (d) 키트 결과물의 사용 및 해석을 위한 설명서
    를 포함하는, 제 3 항에 따른 방법을 수행하는데 적합한 키트.
  28. (a) 모든 전사 변이형을 포함하는 셉틴 9, FOXL2, SARM1, VTN, PRDM6, NR2E1, FAT 및 서열 번호:160 내지 서열 번호:165로 이루어진 군으로부터 선택되는 하나 이상의 유전자 또는 게놈 서열의 폴리펩타이드를 검출하기 위한 수단;
    (b) 폴리펩타이드와 착체를 형성할 수 있는 상기 수단, 및 폴리펩타이드를 포함하는 환자의 생물학적 샘플을 함유하는데 적합한 용기;
    (c) (b)의 착체를 검출하는 수단
    을 포함하는, 제 5 항에 따른 방법을 수행하는데 적합한 키트.
  29. (a) 바이설파이트 시약;
    (b) 상기 바이설파이트 시약 및 환자의 생물학적 샘플을 함유하는데 적합한 용기;
    (c) 각각의 경우 그의 서열이 서열 번호:10 내지 서열 번호:15, 서열 번호:28 내지 서열 번호:33, 서열 번호:30 내지 서열 번호:31, 서열 번호:42 내지 서열 번호:43, 서열 번호:38 내지 서열 번호:39, 서열 번호:50 내지 서열 번호:51, 서열 번호:168 내지 서열 번호:203으로부터 선택되는 서열의 염기 9개 이상, 바람직하게는 18개의 길이를 갖는 구획과 동일하거나, 그에 상보적이거나, 또는 엄격하거나 매우 엄격한 조건하에서 상기 구획과 하이브리드 형성하는 두 개의 올리고뉴클레오타이드를 함유하는 올리고뉴클레오타이드의 하나 이상의 세트
    를 포함하는, 제 9 항에 따른 방법을 수행하는데 적합한 키트.
  30. (a) 메틸화 민감성 제한 효소 시약;
    (b) 상기 시약 및 환자의 생물학적 샘플을 함유하는데 적합한 용기;
    (c) 서열 번호:1 내지 서열 번호:3, 서열 번호:24, 서열 번호:28, 서열 번호:159 내지 서열 번호:167로부터 선택되는 서열의 염기 9개 이상의 길이를 갖는 구획과 동일하거나, 그에 상보적이거나, 또는 엄격하거나 매우 엄격한 조건 하에서 상기 구획과 하이브리드 형성하는 하나 또는 복수개의 핵산 또는 펩타이드 핵산의 올리고뉴클레오타이드의 하나 이상의 세트; 및
    임의적으로, (d) 키트 결과물의 사용 및 해석을 위한 설명서
    를 포함하는, 제 9 항에 따른 방법을 수행하는데 적합한 키트.
  31. 세포 증식 질환의 진단 및/또는 분류에서의, 제 1 항 내지 제 21 항중 어느 한 항에 따른 방법, 제 22 항 내지 제 26 항중 어느 한 항에 따른 핵산 및/또는 제 27 항 내지 제 30 항중 어느 한 항에 따른 키트의 용도.
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KR101527283B1 (ko) * 2013-08-13 2015-06-10 서울대학교산학협력단 당단백질의 탈당화 검출을 통한 암 마커 스크리닝 방법 및 간세포암 마커
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