Nothing Special   »   [go: up one dir, main page]

IL97821A0 - 3,5-disubstituted 2-isoxazolines and isoxazoles,processes for their preparation,agents containing them and their use - Google Patents

3,5-disubstituted 2-isoxazolines and isoxazoles,processes for their preparation,agents containing them and their use

Info

Publication number
IL97821A0
IL97821A0 IL97821A IL9782191A IL97821A0 IL 97821 A0 IL97821 A0 IL 97821A0 IL 97821 A IL97821 A IL 97821A IL 9782191 A IL9782191 A IL 9782191A IL 97821 A0 IL97821 A0 IL 97821A0
Authority
IL
Israel
Prior art keywords
isoxazolines
isoxazoles
disubstituted
processes
preparation
Prior art date
Application number
IL97821A
Other languages
English (en)
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of IL97821A0 publication Critical patent/IL97821A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/04—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/18—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6527—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07F9/653—Five-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Psychiatry (AREA)
  • Biochemistry (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL97821A 1990-04-12 1991-04-10 3,5-disubstituted 2-isoxazolines and isoxazoles,processes for their preparation,agents containing them and their use IL97821A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4011880 1990-04-12

Publications (1)

Publication Number Publication Date
IL97821A0 true IL97821A0 (en) 1992-06-21

Family

ID=6404301

Family Applications (1)

Application Number Title Priority Date Filing Date
IL97821A IL97821A0 (en) 1990-04-12 1991-04-10 3,5-disubstituted 2-isoxazolines and isoxazoles,processes for their preparation,agents containing them and their use

Country Status (16)

Country Link
US (1) US5273989A (pt)
EP (1) EP0451790A1 (pt)
JP (1) JPH04234857A (pt)
KR (1) KR910018363A (pt)
CN (1) CN1055537A (pt)
AU (1) AU7428591A (pt)
BR (1) BR9101475A (pt)
CA (1) CA2040219A1 (pt)
CS (1) CS101391A2 (pt)
FI (1) FI911718A (pt)
HU (1) HU911183D0 (pt)
IE (1) IE911235A1 (pt)
IL (1) IL97821A0 (pt)
NO (1) NO911432L (pt)
PT (1) PT97329A (pt)
ZA (1) ZA912701B (pt)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994020475A1 (en) * 1993-03-02 1994-09-15 Fujisawa Pharmaceutical Co., Ltd. Isoxazole derivative
ATE187447T1 (de) * 1993-11-26 1999-12-15 Pfizer 3-phenyl-2-isoxazoline derivate als entzündugshemmende mittel
KR0182324B1 (ko) * 1993-11-26 1999-05-01 알렌 제이. 스피겔 항염증제로서의 이속사졸린 화합물
US5767118A (en) * 1994-10-26 1998-06-16 Merck & Co., Inc. 4-Heterocyclic peperidines promote release of growth hormone
FR2752163B1 (fr) * 1996-08-12 1998-10-30 Pf Medicament Utilisation de l'efaroxan pour la fabricaton de medicament destine au traitement de la maladie de huntington
KR19990011062A (ko) * 1997-07-21 1999-02-18 손욱 이소옥사졸리딘 고리 함유 액정화합물 및 이를 포함하고 있는 액정 조성물
US6319937B1 (en) * 1998-11-18 2001-11-20 Dupont Pharmaceuticals Company Isoxazoline fibrinogen receptor antagonists
CA2383086A1 (en) 1999-09-08 2001-03-15 Joseph P. Steiner Non-peptidic cyclophilin binding compounds and their use
US6656971B2 (en) 2001-01-25 2003-12-02 Guilford Pharmaceuticals Inc. Trisubstituted carbocyclic cyclophilin binding compounds and their use
EP1491535A4 (en) * 2002-03-07 2009-09-23 Sds Biotech Corp SUBSTITUTED ISOXAZOLALKYLAMINE DERIVATIVE AND FUNGICIDE FOR AGRICULTURE AND GARDENING
ATE350369T1 (de) 2003-08-20 2007-01-15 Lilly Co Eli Verbindungen, verfahren und formulierungen zur oralen verabreichung einer glucagon like peptide (glp)-1-verbindung oder eines am melanocortin-4- rezeptor (mc4) als agonist wirkenden peptids
EP1658285B1 (en) * 2003-08-20 2007-05-02 Eli Lilly And Company Compounds, methods and formulations for the oral delivery of a glucagon like peptide (glp)-1 compound or an melanocortin 4 receptor (mc4) agonist peptide
US20080234132A1 (en) * 2004-11-19 2008-09-25 Laurence Coquin Microcin B17 Analogs And Methods For Their Preparation And Use
JP2010533644A (ja) * 2007-05-31 2010-10-28 聡美 庭山 ハーフエステルの合成方法
US9149465B2 (en) * 2009-05-18 2015-10-06 Infinity Pharmaceuticals, Inc. Isoxazolines as inhibitors of fatty acid amide hydrolase
US8765735B2 (en) * 2009-05-18 2014-07-01 Infinity Pharmaceuticals, Inc. Isoxazolines as inhibitors of fatty acid amide hydrolase
US8927551B2 (en) * 2009-05-18 2015-01-06 Infinity Pharmaceuticals, Inc. Isoxazolines as inhibitors of fatty acid amide hydrolase
ES2907626T3 (es) * 2015-02-27 2022-04-25 Seed Res Institute Co Ltd Método para producir kakeromicina y sus derivados
HUE059708T2 (hu) * 2016-11-08 2022-12-28 Bristol Myers Squibb Co 3-szubsztituált propionsavak mint alfa-V-integrin inhibitorok
CN111333590B (zh) * 2018-12-18 2022-05-17 沈阳中化农药化工研发有限公司 一种异恶唑烷盐酸盐的制备方法
CN113149926B (zh) * 2021-04-30 2023-05-26 华侨大学 一种3,5-二取代异恶唑衍生物的制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA826165A (en) * 1969-10-28 Gagneux Andre Process for the production of an isoxazole derivative
US3152139A (en) * 1961-10-17 1964-10-06 Geigy Chem Corp Certain aminoisoxazolone derivatives
CH450423A (de) * 1965-06-03 1968-01-31 Geigy Ag J R Verfahren zur Herstellung von 3-Hydroxy-5-aminomethyl-isoxazol
DK150615C (da) * 1982-10-26 1987-11-09 Cheminova As Fremgangsmaade til fremstilling af substituerede 3-isoxazololer
CA1261335A (en) * 1984-08-29 1989-09-26 Hoffmann-La Roche Limited/Hoffmann-La Roche Limitee Ethylenediamine monoamide derivatives
WO1988009330A1 (en) * 1987-05-20 1988-12-01 Zambon Group S.P.A. Isoxazoles with nootropic activity
DE3736113A1 (de) * 1987-10-26 1989-05-03 Hoechst Ag Arzneimittel, darin enthaltene phosphorhaltige 2-isoxazoline und isoxazole, sowie herstellungsverfahren fuer diese heterocyclischen verbindungen
DE3914969A1 (de) * 1989-05-02 1990-11-08 Schering Ag 5-substituierte 3-arylisoxazol-derivate, deren herstellung und verwendung als schaedlingsbekaempfungsmittel
JP2786683B2 (ja) * 1989-08-15 1998-08-13 三共株式会社 グリコール誘導体およびその用途

Also Published As

Publication number Publication date
ZA912701B (en) 1991-12-24
FI911718A0 (fi) 1991-04-10
JPH04234857A (ja) 1992-08-24
IE911235A1 (en) 1991-10-23
HU911183D0 (en) 1991-10-28
NO911432L (no) 1991-10-14
AU7428591A (en) 1991-10-17
BR9101475A (pt) 1991-11-26
KR910018363A (ko) 1991-11-30
CA2040219A1 (en) 1991-10-13
CN1055537A (zh) 1991-10-23
CS101391A2 (en) 1991-11-12
NO911432D0 (no) 1991-04-11
EP0451790A1 (de) 1991-10-16
PT97329A (pt) 1992-01-31
US5273989A (en) 1993-12-28
FI911718A (fi) 1991-10-13

Similar Documents

Publication Publication Date Title
ZA912701B (en) 3,5-disubstituted 2-isoxazolines and isoxazoles,processes for their preparation,agents containing them and their use
IL96458A0 (en) Isoxazolines,their preparation,and their use as plantprotecting agents
EP0523141A4 (en) Substituted pyrazoles, isoxazoles and isothiazoles
HK19496A (en) Use of 1,2,2,3,3-penta-fluoropropane
PH24746A (en) 2,3-d/substituted isoxazolidines, agents containing them and their use
IL86901A0 (en) 6,7-dihydropyrazolo-(1,5-a)(1,3,5)triazine-2-sulphonamide derivatives and herbicidal compositions containing the same
ZA916500B (en) Plant-protecting agents containing isoxazolines or isothiazolines,and novel isoxazolines and isothiazolines
IL94764A0 (en) Endoparasiticidal agents containing 3-hydroxybenzothiophenes,certain new such compounds and their preparation
GB2066812B (en) 5'-acyl-uridine derivatives and processes for the preparation thereof
IL95050A0 (en) 5-substituted 1,3,4-thiadiazole derivatives,and pesticidal compositions containing the same
GB2240780B (en) Substituted 1,3-diaminobenzenes,processes for their preparation and colouring agents containing them
IL85942A0 (en) 1,5-substituted 1h-imidazoles,their preparation and their use as herbicides
ZA875446B (en) New 1,4-benzodiazepines,the preparation and use thereof
IL98309A0 (en) Plant-protecting substituted isoxazolines,isoxazoles,isothiozolines and isothiazoles,processes for their preparation and their use
IL86028A0 (en) Novel pyrrolidine-2-(1,3-dicarbonyl)derivatives,their preparation,agents containing them,and their use
IL93339A0 (en) 2,3,23-trihydroxy-urs-12-ene and its derivatives,processes for their preparation and their use
ZA916433B (en) Novel pyrrolobenzimidazoles,imidazobenzoxazinones and imidazoquinolones,process for their preparation and their use and preparations containing the compounds
ZA872720B (en) Derivative of 1,5-diphenyl-1h-1,2,4-triazole-3-carboxamide and herbicidal composition containing the same
IL94057A0 (en) 5-substituted 3-arylisoxazole derivatives and insecticidal compositions containing the same
IL100187A0 (en) Process for the preparation of bromonitro-alcohols,dibromonitro-alcohols and mixtures thereof
PH22967A (en) Bis-tert.-butylamino-substituted 1,3,5-triazine derivatives, medidaments containing these compounds and their use
HU913818D0 (en) New 2,6-alkoxy-phenyl-alkyl-ketones and herbicide preparatives containing said compounds
OA09328A (en) "Heterocyclic compounds".
EP0284422A3 (en) 4,5-dihydro-1h-1,2,4-triazole-3-carboxamide derivatives and herbicidal composition containing the same
IL85449A (en) 26,27-mono-and 14,15:26,27-diepoxide 23-deoxy-ll-f28249 derivatives and parasiticidal use