IL143150A0 - A process for the preparation of n,n'-bis[2,3-dihydroxypropyl]-5[hydroxyacetyl) methylamino]-2,4,5-triiodo-1,3-benzenedicarboxamide - Google Patents

A process for the preparation of n,n'-bis[2,3-dihydroxypropyl]-5[hydroxyacetyl) methylamino]-2,4,5-triiodo-1,3-benzenedicarboxamide

Info

Publication number: IL143150A0
Authority: IL; Israel
Prior art keywords: triiodo; hydroxyacetyl; dihydroxypropyl; methylamino; bis
Prior art date: 1998-11-27

Application number

IL14315099A

Other languages

English (en)

Original Assignee

Bracco Int Bv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-11-27

Filing date

1999-11-25

Publication date

2002-04-21

1999-11-25 Application filed by Bracco Int Bv filed Critical Bracco Int Bv

2002-04-21 Publication of IL143150A0 publication Critical patent/IL143150A0/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/14—Preparation of carboxylic acid amides by formation of carboxamide groups together with reactions not involving the carboxamide groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Polyamides (AREA)

IL14315099A 1998-11-27 1999-11-25 A process for the preparation of n,n'-bis[2,3-dihydroxypropyl]-5[hydroxyacetyl) methylamino]-2,4,5-triiodo-1,3-benzenedicarboxamide IL143150A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IT1998MI002574A IT1303797B1 (it)	1998-11-27	1998-11-27	Processo per la preparazione di n,n'-bis(2,3-diidrossipropil)-5-((idrossiacetil)metilammino)-2,4,6-triiodo-1,3-benzendicarbossammide.
PCT/EP1999/009118 WO2000032561A1 (en)	1998-11-27	1999-11-25	A process for the preparation of n,n'-bis[2, 3-dihydroxypropyl] -5-[ (hydroxyacetyl) methylamino]-2, 4,6-triiodo-1, 3-benzenedi carboxamide

Publications (1)

Publication Number	Publication Date
IL143150A0 true IL143150A0 (en)	2002-04-21

Family

ID=11381150

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL14315099A IL143150A0 (en)	1998-11-27	1999-11-25	A process for the preparation of n,n'-bis[2,3-dihydroxypropyl]-5[hydroxyacetyl) methylamino]-2,4,5-triiodo-1,3-benzenedicarboxamide

Country Status (24)

Country	Link
US (1)	US6420603B1 (ru)
EP (1)	EP1133466B1 (ru)
JP (1)	JP4439123B2 (ru)
KR (1)	KR100630400B1 (ru)
CN (1)	CN1163474C (ru)
AT (1)	ATE247630T1 (ru)
AU (1)	AU753601B2 (ru)
BR (1)	BR9915608B1 (ru)
CA (1)	CA2351717C (ru)
CZ (1)	CZ296096B6 (ru)
DE (1)	DE69910609T2 (ru)
EA (1)	EA003253B1 (ru)
ES (1)	ES2205949T3 (ru)
HK (1)	HK1040988B (ru)
HR (1)	HRP20010393B1 (ru)
HU (1)	HU229092B1 (ru)
IL (1)	IL143150A0 (ru)
IT (1)	IT1303797B1 (ru)
ME (2)	MEP8809A (ru)
NO (1)	NO327037B1 (ru)
RS (1)	RS50038B (ru)
SK (1)	SK285050B6 (ru)
TR (1)	TR200101439T2 (ru)
WO (1)	WO2000032561A1 (ru)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP2093206A1 (en) *	2008-02-20	2009-08-26	BRACCO IMAGING S.p.A.	Process for the iodination of aromatic compounds
EP2243767A1 (en)	2009-04-21	2010-10-27	Bracco Imaging S.p.A	Process for the iodination of aromatic compounds
AU2010270302B2 (en) *	2009-07-07	2014-08-07	Bracco Imaging Spa	Process for the preparation of a iodinating agent
EP2277846A1 (en) *	2009-07-21	2011-01-26	GE Healthcare AS	Obtaining free iodine in preparation of aqueous iodine chloride by adding potassium iodide
EP2394984A1 (en)	2010-06-10	2011-12-14	Bracco Imaging S.p.A	Process for the iodination of phenolic derivatives
IT1403988B1 (it) *	2010-07-15	2013-11-08	Bracco Imaging Spa	Processo per la preparazione di agenti di contrasto.
WO2012136813A2 (en)	2011-04-07	2012-10-11	Universitetet I Oslo	Agents for medical radar diagnosis
KR101833334B1 (ko) *	2016-04-29	2018-02-28	(주)유케이케미팜	신규 중간체 화합물 및 이를 이용한 이오메프롤의 제조방법
KR102128423B1 (ko)	2018-09-17	2020-07-01	(주)유케이케미팜	조영제 이오메프롤의 제조방법
US12129563B2 (en)	2021-09-24	2024-10-29	Bracco Imaging S.P.A.	Electrochemical iodination of N,N′-(2,3-dihydroxypropyl)-5-hydroxy-1,3-benzenedicarboxamide
WO2023209165A1 (en)	2022-04-29	2023-11-02	Bracco Imaging Spa	Process for the preparation of 2,4,6-triiodophenol derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1196363B (it) *	1984-12-10	1988-11-16	Bracco Ind Chimica Spa	Derivati dell'acido 5-alcossi-2,4,6-triiodo- o -tribromo-isoftalico,metodo per la loro preparazione e relativi mezzi di contrasto radiologici
EP0365541B1 (en) *	1987-05-22	1992-08-12	BRACCO S.p.A.	Preparation of 5-acylamino-2,4,6-triiodo- or tribromo-benzoic acid derivatives

1998
- 1998-11-27 IT IT1998MI002574A patent/IT1303797B1/it active
1999
- 1999-11-25 TR TR2001/01439T patent/TR200101439T2/xx unknown
- 1999-11-25 EA EA200100462A patent/EA003253B1/ru not_active IP Right Cessation
- 1999-11-25 DE DE69910609T patent/DE69910609T2/de not_active Expired - Lifetime
- 1999-11-25 US US09/856,554 patent/US6420603B1/en not_active Expired - Lifetime
- 1999-11-25 ME MEP-88/09A patent/MEP8809A/xx unknown
- 1999-11-25 EP EP99973018A patent/EP1133466B1/en not_active Expired - Lifetime
- 1999-11-25 JP JP2000585203A patent/JP4439123B2/ja not_active Expired - Lifetime
- 1999-11-25 RS YUP-371/01A patent/RS50038B/sr unknown
- 1999-11-25 CA CA2351717A patent/CA2351717C/en not_active Expired - Lifetime
- 1999-11-25 HU HU0104507A patent/HU229092B1/hu unknown
- 1999-11-25 ES ES99973018T patent/ES2205949T3/es not_active Expired - Lifetime
- 1999-11-25 AU AU13862/00A patent/AU753601B2/en not_active Expired
- 1999-11-25 KR KR1020017006458A patent/KR100630400B1/ko active IP Right Grant
- 1999-11-25 WO PCT/EP1999/009118 patent/WO2000032561A1/en active IP Right Grant
- 1999-11-25 SK SK705-2001A patent/SK285050B6/sk not_active IP Right Cessation
- 1999-11-25 CZ CZ20011833A patent/CZ296096B6/cs not_active IP Right Cessation
- 1999-11-25 ME MEP-2009-88A patent/ME00606B/me unknown
- 1999-11-25 CN CNB998136514A patent/CN1163474C/zh not_active Expired - Lifetime
- 1999-11-25 IL IL14315099A patent/IL143150A0/xx not_active IP Right Cessation
- 1999-11-25 BR BRPI9915608-3A patent/BR9915608B1/pt not_active IP Right Cessation
- 1999-11-25 AT AT99973018T patent/ATE247630T1/de active
2001
- 2001-05-23 HR HR20010393A patent/HRP20010393B1/xx not_active IP Right Cessation
- 2001-05-23 NO NO20012547A patent/NO327037B1/no not_active IP Right Cessation
2002
- 2002-04-12 HK HK02102762.0A patent/HK1040988B/zh not_active IP Right Cessation

Also Published As

Publication number	Publication date
CN1328539A (zh)	2001-12-26
HK1040988A1 (en)	2002-06-28
CN1163474C (zh)	2004-08-25
EP1133466B1 (en)	2003-08-20
NO327037B1 (no)	2009-04-06
ME00606B (me)	2011-12-20
HUP0104507A2 (hu)	2002-04-29
KR20010101053A (ko)	2001-11-14
HRP20010393B1 (en)	2004-04-30
CA2351717A1 (en)	2000-06-08
DE69910609T2 (de)	2004-03-18
WO2000032561A1 (en)	2000-06-08
KR100630400B1 (ko)	2006-10-02
IT1303797B1 (it)	2001-02-23
US6420603B1 (en)	2002-07-16
NO20012547D0 (no)	2001-05-23
CA2351717C (en)	2010-10-05
BR9915608A (pt)	2001-08-14
EA200100462A1 (ru)	2001-12-24
YU37101A (sh)	2003-04-30
HRP20010393A2 (en)	2002-06-30
JP4439123B2 (ja)	2010-03-24
ITMI982574A1 (it)	2000-05-27
ES2205949T3 (es)	2004-05-01
EA003253B1 (ru)	2003-02-27
JP2002531432A (ja)	2002-09-24
SK285050B6 (sk)	2006-05-04
NO20012547L (no)	2001-07-25
CZ20011833A3 (cs)	2001-10-17
ATE247630T1 (de)	2003-09-15
HUP0104507A3 (en)	2004-07-28
TR200101439T2 (tr)	2001-10-22
RS50038B (sr)	2008-11-28
AU1386200A (en)	2000-06-19
BR9915608B1 (pt)	2010-11-16
CZ296096B6 (cs)	2006-01-11
HU229092B1 (en)	2013-07-29
MEP8809A (en)	2011-12-20
HK1040988B (zh)	2005-04-29
SK7052001A3 (en)	2001-12-03
DE69910609D1 (de)	2003-09-25
EP1133466A1 (en)	2001-09-19
AU753601B2 (en)	2002-10-24

Publication	Publication Date	Title
IL143150A0 (en)	2002-04-21	A process for the preparation of n,n'-bis[2,3-dihydroxypropyl]-5[hydroxyacetyl) methylamino]-2,4,5-triiodo-1,3-benzenedicarboxamide
IL157478A0 (en)	2004-03-28	Method for the synthesis of 2', 3'-didehydronucleosides
MXPA04004939A (es)	2004-08-11	5,5??,6,6??,7,7??,8,8??-octahidro-2,2??-binaftoles 3-alquilados y 5,5??,6,6??,7,7??,8,8??-octahidro-2,2??-binaftoles 3,3??-dialquilados y procesos para su fabricacion.
CA2364819A1 (en)	2000-08-31	Process for the preparation of iopamidol
GB2383041B (en)	2004-11-17	Process for the preparation of gabapentin
EP0839056A4 (en)	2000-09-13	METHOD FOR PRODUCING IOVERSOL
IL133279A0 (en)	2001-04-30	Carboxamides useful as 5-ht1f agonists
ZA9710862B (en)	1998-06-23	A process for the preparation of 5-amino-2,4,6-triiodo-1,3-benzenedicarboxylic acid derivatives.
EP0886634A4 (en)	2000-08-02	METHOD FOR PRODUCING IOVERSOL
BR9711381A (pt)	1999-08-17	Processos para a produ-Æo e a purifica-Æo de ioxol
IL133100A0 (en)	2001-03-19	Yellow polymorph of 5-amino-2,4,6-triiodo-n,n'-bis (2,3-dihydroxypropyl)-isophthalamide
GB9825095D0 (en)	1999-01-13	Chemical process
HUP9801837A3 (en)	2001-06-28	Process for the crystallization from water of (s)-n,n'-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-[(2-hydroxy-1-oxopropyl)amino]-2,4,6-triiodo-1,3-benzendicarboxamide
SI1133466T1 (en)	2003-12-31	A process for the preparation of n,n'-bis 2, 3-dihydroxypropyl) -5-((hydroxyacetyl) methylamino)-2, 4,6-triiodo-1, 3-benzenedi carboxamide
MX220674B (en)	2004-05-28	Process for hydrolysis of adiponitrile and prodn. of nylon 6,6 utilizing low catalyst levels
IL161642A0 (en)	2004-09-27	IMPROVED PURIFICATION OF 4,4'(5')-DI-t-BUTYLCYCLOHEXANO-18-CROWN-6
MXPA04006085A (es)	2004-09-27	Compuestos de isocromano para el tratamiento de trastornos del sistema nervioso central.

Legal Events

Date	Code	Title
2006-08-01	FF	Patent granted
2013-11-28	KB	Patent renewed
2017-11-30	KB	Patent renewed
2020-06-30	EXP	Patent expired