IL146441A0 - Purine derivatives, preparation method and pharmaceutical compositions containing same - Google Patents

Purine derivatives, preparation method and pharmaceutical compositions containing same

Info

Publication number: IL146441A0
Authority: IL; Israel
Prior art keywords: preparation; pharmaceutical compositions; compositions containing; containing same; purine derivatives
Prior art date: 1999-05-21

Application number

IL14644100A

Other languages

English (en)

Original Assignee

Aventis Pharma Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-05-21

Filing date

2000-05-18

Publication date

2002-07-25

2000-05-18 Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa

2002-07-25 Publication of IL146441A0 publication Critical patent/IL146441A0/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/24—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one nitrogen and one sulfur atom

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Communicable Diseases (AREA)
Dermatology (AREA)
Hospice & Palliative Care (AREA)
Oncology (AREA)
Tropical Medicine & Parasitology (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

IL14644100A 1999-05-21 2000-05-18 Purine derivatives, preparation method and pharmaceutical compositions containing same IL146441A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9906456A FR2793794B1 (fr)	1999-05-21	1999-05-21	Nouveaux derives de la purine, leur procede de preparation, leur application a titre de medicaments, compositions pharmaceutiques et nouvelle utilisation
PCT/FR2000/001335 WO2000071543A1 (fr)	1999-05-21	2000-05-18	Derives de la purine, leur procede de preparation, et compositions pharmaceutiques les contenant

Publications (1)

Publication Number	Publication Date
IL146441A0 true IL146441A0 (en)	2002-07-25

Family

ID=9545846

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL14644100A IL146441A0 (en)	1999-05-21	2000-05-18	Purine derivatives, preparation method and pharmaceutical compositions containing same

Country Status (33)

Country	Link
US (2)	US7122669B1 (xx)
EP (1)	EP1183256B1 (xx)
JP (1)	JP2003500407A (xx)
KR (1)	KR100707895B1 (xx)
CN (1)	CN1298719C (xx)
AP (1)	AP1477A (xx)
AR (1)	AR035317A1 (xx)
AT (1)	ATE370951T1 (xx)
AU (1)	AU4764500A (xx)
BR (1)	BR0011282A (xx)
CA (1)	CA2374714A1 (xx)
CZ (1)	CZ20014163A3 (xx)
DE (1)	DE60036102T2 (xx)
DK (1)	DK1183256T3 (xx)
DZ (1)	DZ3166A1 (xx)
EA (1)	EA005072B1 (xx)
ES (1)	ES2290033T3 (xx)
FR (1)	FR2793794B1 (xx)
HU (1)	HUP0201649A3 (xx)
IL (1)	IL146441A0 (xx)
MA (1)	MA26791A1 (xx)
MX (1)	MXPA01011834A (xx)
NO (1)	NO20015659L (xx)
NZ (1)	NZ515556A (xx)
PL (1)	PL352293A1 (xx)
PT (1)	PT1183256E (xx)
SK (1)	SK16722001A3 (xx)
TR (1)	TR200103349T2 (xx)
TW (1)	TWI284130B (xx)
UA (1)	UA68441C2 (xx)
WO (1)	WO2000071543A1 (xx)
YU (1)	YU86601A (xx)
ZA (1)	ZA200109602B (xx)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6479487B1 (en) *	1998-02-26	2002-11-12	Aventis Pharmaceuticals Inc.	6, 9-disubstituted 2-[trans-(4-aminocyclohexyl)amino] purines
US6413974B1 (en) *	1998-02-26	2002-07-02	Aventis Pharmaceuticals Inc.	6,9,-disubstituted 2-[trans-(4-aminocyclohexyl) amino] purines
US6969720B2 (en)	1999-03-17	2005-11-29	Amr Technology, Inc.	Biaryl substituted purine derivatives as potent antiproliferative agents
US6861524B2 (en) *	2000-10-31	2005-03-01	Aventis Pharmaceuticals Inc.	Acyl and sulfonyl derivatives of 6,9-disubstituted 2-(trans-1,4-diaminocyclohexyl)-purines and their use as antiproliferative agents
BR0115080A (pt) *	2000-10-31	2003-09-23	Aventis Pharma Inc	Derivados de acila e sulfonila de 2-(trans-1,4-diaminocicloexil)-purinas 6,9-dissubstituìdas e o uso destes como agentes antiproliferativos
FR2818642B1 (fr) *	2000-12-26	2005-07-15	Hoechst Marion Roussel Inc	Nouveaux derives de la purine, leur procede de preparation, leur application a titre de medicaments, compositions pharmaceutiques et nouvelle utilistion
US6667311B2 (en) *	2001-09-11	2003-12-23	Albany Molecular Research, Inc.	Nitrogen substituted biaryl purine derivatives as potent antiproliferative agents
US6812232B2 (en)	2001-09-11	2004-11-02	Amr Technology, Inc.	Heterocycle substituted purine derivatives as potent antiproliferative agents
CA2463563A1 (en) *	2001-10-12	2003-04-17	Irm Llc	Kinase inhibitor scaffolds and methods for their preparation
JP4664205B2 (ja) *	2002-10-15	2011-04-06	アイアールエムエルエルシー	骨形成を誘導する組成物および方法
FR2851248B1 (fr) *	2003-02-18	2005-04-08	Aventis Pharma Sa	Nouveaux derives de la purine, leur procede de preparation, leur application a titre de medicaments, compositions pharmaceutiques et nouvelle utilisation
WO2005047524A2 (en)	2003-11-10	2005-05-26	The Scripps Research Institute	Compositions and methods for inducing cell dedifferentiation
AU2005231440B9 (en) *	2004-04-02	2012-02-23	Dogwood Pharmaceuticals, Inc.	Selective antagonists of A2A adenosine receptors
CZ302122B6 (cs) *	2009-01-28	2010-10-20	Univerzita Palackého v Olomouci	Substituované deriváty 6-(2-aminobenzylamino)purinu, jejich použití jako léciva a prípravky tyto slouceniny obsahující
WO2012142029A2 (en)	2011-04-10	2012-10-18	Florida A&M University	Serms for the treatment of estrogen receptor-mediated disorders
EP3134405B1 (en)	2014-04-25	2019-08-28	Pfizer Inc	Heteroaromatic compounds and their use as dopamine d1 ligands
CN114149432B (zh) *	2016-09-30	2024-07-05	斯坦福国际研究院	用于癌症治疗的双重clk/cdk1抑制剂
CZ308029B6 (cs) *	2017-03-20	2019-11-06	Univerzita PalackĂ©ho v Olomouci	2,6-Disubstituované-9-cyklopentyl-9H-puriny, jejich použití jako léčiva a farmaceutické přípravky

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4008858A1 (de) *	1990-03-20	1991-09-26	Hoechst Ag	Substituierte purine, verfahren zu ihrer hertellung sowie ihre verwendung als antivirale mittel
DE69231194T2 (de) *	1991-12-05	2001-02-15	Texas Instruments Inc., Dallas	Verfahren zur Verbesserung eines Videosignals
AU658698B2 (en) *	1991-12-06	1995-04-27	Aventis Pharmaceuticals Inc.	Novel trans cyclopentanyl purine analogs useful as immunosuppressants
CA2234609C (en) *	1995-11-01	2006-11-28	Novartis Ag	2-amino-6-anilino-purine derivatives and processes for their preparation
FR2741881B1 (fr) *	1995-12-01	1999-07-30	Centre Nat Rech Scient	Nouveaux derives de purine possedant notamment des prorietes anti-proliferatives et leurs applications biologiques
US5866702A (en) *	1996-08-02	1999-02-02	Cv Therapeutics, Incorporation	Purine inhibitors of cyclin dependent kinase 2
US6790958B2 (en) *	1996-08-02	2004-09-14	Robert T. Lum	Purine inhibitors of cyclin dependent kinase 2 & IKBA
US6153618A (en) *	1996-10-11	2000-11-28	Chiron Corporation	Inhibitors of glycogen synthase 3 kinase
AU735127B2 (en) *	1997-08-07	2001-06-28	Regents Of The University Of California, The	Purine inhibitor of protein kinases, G proteins and polymerases
US6413974B1 (en) *	1998-02-26	2002-07-02	Aventis Pharmaceuticals Inc.	6,9,-disubstituted 2-[trans-(4-aminocyclohexyl) amino] purines
US6479487B1 (en) *	1998-02-26	2002-11-12	Aventis Pharmaceuticals Inc.	6, 9-disubstituted 2-[trans-(4-aminocyclohexyl)amino] purines
GB9903762D0 (en) *	1999-02-18	1999-04-14	Novartis Ag	Organic compounds
FR2818642B1 (fr) *	2000-12-26	2005-07-15	Hoechst Marion Roussel Inc	Nouveaux derives de la purine, leur procede de preparation, leur application a titre de medicaments, compositions pharmaceutiques et nouvelle utilistion

1999
- 1999-05-21 FR FR9906456A patent/FR2793794B1/fr not_active Expired - Fee Related
2000
- 2000-05-09 TW TW089108817A patent/TWI284130B/zh not_active IP Right Cessation
- 2000-05-18 PT PT00929625T patent/PT1183256E/pt unknown
- 2000-05-18 SK SK1672-2001A patent/SK16722001A3/sk unknown
- 2000-05-18 AU AU47645/00A patent/AU4764500A/en not_active Abandoned
- 2000-05-18 MX MXPA01011834A patent/MXPA01011834A/es active IP Right Grant
- 2000-05-18 WO PCT/FR2000/001335 patent/WO2000071543A1/fr active IP Right Grant
- 2000-05-18 NZ NZ515556A patent/NZ515556A/en unknown
- 2000-05-18 YU YU86601A patent/YU86601A/sh unknown
- 2000-05-18 JP JP2000619799A patent/JP2003500407A/ja not_active Abandoned
- 2000-05-18 AT AT00929625T patent/ATE370951T1/de not_active IP Right Cessation
- 2000-05-18 EA EA200101224A patent/EA005072B1/ru not_active IP Right Cessation
- 2000-05-18 HU HU0201649A patent/HUP0201649A3/hu unknown
- 2000-05-18 IL IL14644100A patent/IL146441A0/xx unknown
- 2000-05-18 BR BR0011282-8A patent/BR0011282A/pt not_active Application Discontinuation
- 2000-05-18 CA CA002374714A patent/CA2374714A1/fr not_active Abandoned
- 2000-05-18 UA UA2001128864A patent/UA68441C2/uk unknown
- 2000-05-18 DZ DZ003166A patent/DZ3166A1/xx active
- 2000-05-18 AP APAP/P/2001/002355A patent/AP1477A/en active
- 2000-05-18 DE DE60036102T patent/DE60036102T2/de not_active Expired - Fee Related
- 2000-05-18 DK DK00929625T patent/DK1183256T3/da active
- 2000-05-18 EP EP00929625A patent/EP1183256B1/fr not_active Expired - Lifetime
- 2000-05-18 US US09/979,389 patent/US7122669B1/en not_active Expired - Fee Related
- 2000-05-18 CZ CZ20014163A patent/CZ20014163A3/cs unknown
- 2000-05-18 KR KR1020017014800A patent/KR100707895B1/ko not_active IP Right Cessation
- 2000-05-18 PL PL00352293A patent/PL352293A1/xx not_active Application Discontinuation
- 2000-05-18 TR TR2001/03349T patent/TR200103349T2/xx unknown
- 2000-05-18 CN CNB008106509A patent/CN1298719C/zh not_active Expired - Fee Related
- 2000-05-18 ES ES00929625T patent/ES2290033T3/es not_active Expired - Lifetime
- 2000-05-19 AR ARP000102428A patent/AR035317A1/es not_active Application Discontinuation
2001
- 2001-11-15 MA MA26410A patent/MA26791A1/fr unknown
- 2001-11-20 NO NO20015659A patent/NO20015659L/no not_active Application Discontinuation
- 2001-11-21 ZA ZA200109602A patent/ZA200109602B/xx unknown
2004
- 2004-12-07 US US11/006,013 patent/US7208598B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
PL352293A1 (en)	2003-08-11
FR2793794B1 (fr)	2001-07-27
ATE370951T1 (de)	2007-09-15
CZ20014163A3 (cs)	2002-10-16
AU4764500A (en)	2000-12-12
JP2003500407A (ja)	2003-01-07
MA26791A1 (fr)	2004-12-20
NZ515556A (en)	2003-08-29
EP1183256A1 (fr)	2002-03-06
WO2000071543A1 (fr)	2000-11-30
EA005072B1 (ru)	2004-10-28
TR200103349T2 (tr)	2002-05-21
HUP0201649A2 (en)	2002-08-28
US20050187228A1 (en)	2005-08-25
AR035317A1 (es)	2004-05-12
UA68441C2 (en)	2004-08-16
YU86601A (sh)	2005-07-19
US7208598B2 (en)	2007-04-24
ES2290033T3 (es)	2008-02-16
EA200101224A1 (ru)	2002-10-31
TWI284130B (en)	2007-07-21
CN1298719C (zh)	2007-02-07
HUP0201649A3 (en)	2003-01-28
NO20015659D0 (no)	2001-11-20
ZA200109602B (en)	2003-01-29
DZ3166A1 (fr)	2000-11-30
SK16722001A3 (sk)	2003-01-09
NO20015659L (no)	2002-01-18
KR100707895B1 (ko)	2007-04-17
AP2001002355A0 (en)	2001-12-31
EP1183256B1 (fr)	2007-08-22
DE60036102D1 (de)	2007-10-04
DK1183256T3 (da)	2007-12-03
DE60036102T2 (de)	2008-05-15
CN1361780A (zh)	2002-07-31
US7122669B1 (en)	2006-10-17
AP1477A (en)	2005-10-19
MXPA01011834A (es)	2002-04-17
FR2793794A1 (fr)	2000-11-24
CA2374714A1 (fr)	2000-11-30
KR20010113975A (ko)	2001-12-28
BR0011282A (pt)	2002-02-26
PT1183256E (pt)	2007-11-13

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