IL110040A - Pyridazinone derivatives their preparation and pharmaceutical compositions comprising them - Google Patents
Pyridazinone derivatives their preparation and pharmaceutical compositions comprising themInfo
- Publication number
- IL110040A IL110040A IL11004094A IL11004094A IL110040A IL 110040 A IL110040 A IL 110040A IL 11004094 A IL11004094 A IL 11004094A IL 11004094 A IL11004094 A IL 11004094A IL 110040 A IL110040 A IL 110040A
- Authority
- IL
- Israel
- Prior art keywords
- group
- atom
- alkyl group
- pct
- hydrogen atom
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/22—Nitrogen and oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/20—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15919493 | 1993-06-29 | ||
JP11272194 | 1994-05-26 |
Publications (2)
Publication Number | Publication Date |
---|---|
IL110040A0 IL110040A0 (en) | 1994-10-07 |
IL110040A true IL110040A (en) | 2000-07-16 |
Family
ID=26451823
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL11004094A IL110040A (en) | 1993-06-29 | 1994-06-17 | Pyridazinone derivatives their preparation and pharmaceutical compositions comprising them |
Country Status (22)
Country | Link |
---|---|
US (2) | US5728702A (xx) |
EP (1) | EP0706517B1 (xx) |
KR (1) | KR100255416B1 (xx) |
CN (1) | CN1044906C (xx) |
AT (1) | ATE172454T1 (xx) |
AU (1) | AU676341B2 (xx) |
CA (1) | CA2166326C (xx) |
CZ (1) | CZ289231B6 (xx) |
DE (1) | DE69414112T2 (xx) |
DK (1) | DK0706517T3 (xx) |
ES (1) | ES2124413T3 (xx) |
FI (1) | FI113963B (xx) |
HU (1) | HU221009B1 (xx) |
IL (1) | IL110040A (xx) |
NO (1) | NO306675B1 (xx) |
NZ (1) | NZ267510A (xx) |
RO (1) | RO114791B1 (xx) |
RU (1) | RU2138486C1 (xx) |
SK (1) | SK280786B6 (xx) |
TW (1) | TW408114B (xx) |
UA (1) | UA34481C2 (xx) |
WO (1) | WO1995001343A1 (xx) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1049892C (zh) * | 1994-01-25 | 2000-03-01 | 日产化学工业株式会社 | 哒嗪酮衍生物及其盐,其制造方法,及抗血小板医药组合物 |
DE4430755A1 (de) * | 1994-08-30 | 1996-03-07 | Boehringer Mannheim Gmbh | Neue Phosphanoxide, Verfahren zu ihrer Herstellung sowie diese Verbindungen enthaltende Arzneimittel |
US6207665B1 (en) | 1997-06-12 | 2001-03-27 | Schering Aktiengesellschaft | Piperazine derivatives and their use as anti-inflammatory agents |
SK14742000A3 (sk) * | 1998-03-31 | 2001-03-12 | Nissan Chemical Industries, Ltd. | Pyridazinónová hydrochloridová zlúčenina a spôsob jej prípravy |
CA2390934C (en) * | 1999-11-11 | 2008-07-15 | Nissan Chemical Industries, Ltd. | Process for producing benzylamine compound |
HUP0401735A3 (en) | 2001-10-22 | 2005-06-28 | Pfizer Prod Inc | Piperazine derivatives with ccr1 receptor antagonist activity and pharmaceutical compositions containing them |
US20060080140A1 (en) * | 2004-02-09 | 2006-04-13 | Epic Systems Corporation | System and method for providing a clinical summary of patient information in various health care settings |
WO2010099388A1 (en) * | 2009-02-27 | 2010-09-02 | Indigo Pharmaceuticals | Combinational use of a pde3 inhibitor and other agents |
CN116768868B (zh) * | 2023-08-15 | 2023-12-08 | 云南省药物研究所 | 一种哒嗪酮硫代衍生物及其制备方法和应用 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0186817B1 (en) * | 1984-12-10 | 1989-08-02 | Nissan Chemical Industries Ltd. | 3(2h)pyridazinone, process for its preparation and anti-allergic agent containing it |
JPH0641454B2 (ja) * | 1985-02-27 | 1994-06-01 | 日産化学工業株式会社 | ピリダジノン誘導体 |
EP0201765B1 (en) * | 1985-04-27 | 1991-09-18 | Nissan Chemical Industries Ltd. | 3(2h)pyridazinone, process for its preparation and anti-allergic agent containing it |
HU198696B (en) * | 1987-01-20 | 1989-11-28 | Nissan Chemical Ind Ltd | Process for producing 3/2h/-pyridazinon derivatives and pharmaceutical compositions containing them as active components |
JPH02256668A (ja) * | 1988-12-20 | 1990-10-17 | Nissan Chem Ind Ltd | ピリダジノン誘導体 |
RU2054004C1 (ru) * | 1990-04-25 | 1996-02-10 | Ниссан Кемикал Индастриз Лтд. | Производные 3(2н)-пиридазинона или их фармацевтически приемлемые соли и фармацевтическая композиция на их основе |
CN1049892C (zh) * | 1994-01-25 | 2000-03-01 | 日产化学工业株式会社 | 哒嗪酮衍生物及其盐,其制造方法,及抗血小板医药组合物 |
-
1994
- 1994-06-17 IL IL11004094A patent/IL110040A/xx not_active IP Right Cessation
- 1994-06-24 US US08/564,277 patent/US5728702A/en not_active Expired - Lifetime
- 1994-06-24 DE DE69414112T patent/DE69414112T2/de not_active Expired - Fee Related
- 1994-06-24 EP EP94918564A patent/EP0706517B1/en not_active Expired - Lifetime
- 1994-06-24 SK SK1624-95A patent/SK280786B6/sk unknown
- 1994-06-24 NZ NZ267510A patent/NZ267510A/en not_active IP Right Cessation
- 1994-06-24 KR KR1019950705969A patent/KR100255416B1/ko not_active IP Right Cessation
- 1994-06-24 HU HU9503807A patent/HU221009B1/hu not_active IP Right Cessation
- 1994-06-24 ES ES94918564T patent/ES2124413T3/es not_active Expired - Lifetime
- 1994-06-24 DK DK94918564T patent/DK0706517T3/da active
- 1994-06-24 CA CA002166326A patent/CA2166326C/en not_active Expired - Fee Related
- 1994-06-24 CN CN94192618A patent/CN1044906C/zh not_active Expired - Fee Related
- 1994-06-24 AU AU69833/94A patent/AU676341B2/en not_active Ceased
- 1994-06-24 UA UA95125405A patent/UA34481C2/uk unknown
- 1994-06-24 AT AT94918564T patent/ATE172454T1/de not_active IP Right Cessation
- 1994-06-24 CZ CZ19953299A patent/CZ289231B6/cs not_active IP Right Cessation
- 1994-06-24 WO PCT/JP1994/001015 patent/WO1995001343A1/en active IP Right Grant
- 1994-06-24 RU RU96101173A patent/RU2138486C1/ru not_active IP Right Cessation
- 1994-06-24 RO RO95-02293A patent/RO114791B1/ro unknown
- 1994-06-25 TW TW083105779A patent/TW408114B/zh not_active IP Right Cessation
-
1995
- 1995-12-28 NO NO955328A patent/NO306675B1/no unknown
- 1995-12-28 FI FI956300A patent/FI113963B/fi not_active IP Right Cessation
-
1997
- 1997-12-08 US US08/986,420 patent/US5929074A/en not_active Expired - Fee Related
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
MM9K | Patent not in force due to non-payment of renewal fees |