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DE69414112D1 - Pyridazinon derivate mit pharmazeutischer wirkung - Google Patents

Pyridazinon derivate mit pharmazeutischer wirkung

Info

Publication number
DE69414112D1
DE69414112D1 DE69414112T DE69414112T DE69414112D1 DE 69414112 D1 DE69414112 D1 DE 69414112D1 DE 69414112 T DE69414112 T DE 69414112T DE 69414112 T DE69414112 T DE 69414112T DE 69414112 D1 DE69414112 D1 DE 69414112D1
Authority
DE
Germany
Prior art keywords
group
atom
alkyl group
pct
hydrogen atom
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69414112T
Other languages
English (en)
Other versions
DE69414112T2 (de
Inventor
Keizo Nissan Chemical Tanikawa
Akira Nissan Chemical In Saito
Mitsuaki Nissan Chem Hirotsuka
Ken-Ichi Nissan Chemic Shikada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nissan Chemical Corp
Original Assignee
Nissan Chemical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nissan Chemical Corp filed Critical Nissan Chemical Corp
Application granted granted Critical
Publication of DE69414112D1 publication Critical patent/DE69414112D1/de
Publication of DE69414112T2 publication Critical patent/DE69414112T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/22Nitrogen and oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50Pyridazines; Hydrogenated pyridazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/20Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE69414112T 1993-06-29 1994-06-24 Pyridazinon derivate mit pharmazeutischer wirkung Expired - Fee Related DE69414112T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP15919493 1993-06-29
JP11272194 1994-05-26
PCT/JP1994/001015 WO1995001343A1 (en) 1993-06-29 1994-06-24 Pyridazinone derivatives with pharmaceutical activity

Publications (2)

Publication Number Publication Date
DE69414112D1 true DE69414112D1 (de) 1998-11-26
DE69414112T2 DE69414112T2 (de) 1999-03-11

Family

ID=26451823

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69414112T Expired - Fee Related DE69414112T2 (de) 1993-06-29 1994-06-24 Pyridazinon derivate mit pharmazeutischer wirkung

Country Status (22)

Country Link
US (2) US5728702A (de)
EP (1) EP0706517B1 (de)
KR (1) KR100255416B1 (de)
CN (1) CN1044906C (de)
AT (1) ATE172454T1 (de)
AU (1) AU676341B2 (de)
CA (1) CA2166326C (de)
CZ (1) CZ289231B6 (de)
DE (1) DE69414112T2 (de)
DK (1) DK0706517T3 (de)
ES (1) ES2124413T3 (de)
FI (1) FI113963B (de)
HU (1) HU221009B1 (de)
IL (1) IL110040A (de)
NO (1) NO306675B1 (de)
NZ (1) NZ267510A (de)
RO (1) RO114791B1 (de)
RU (1) RU2138486C1 (de)
SK (1) SK280786B6 (de)
TW (1) TW408114B (de)
UA (1) UA34481C2 (de)
WO (1) WO1995001343A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1049892C (zh) * 1994-01-25 2000-03-01 日产化学工业株式会社 哒嗪酮衍生物及其盐,其制造方法,及抗血小板医药组合物
DE4430755A1 (de) * 1994-08-30 1996-03-07 Boehringer Mannheim Gmbh Neue Phosphanoxide, Verfahren zu ihrer Herstellung sowie diese Verbindungen enthaltende Arzneimittel
US6207665B1 (en) 1997-06-12 2001-03-27 Schering Aktiengesellschaft Piperazine derivatives and their use as anti-inflammatory agents
SK14742000A3 (sk) * 1998-03-31 2001-03-12 Nissan Chemical Industries, Ltd. Pyridazinónová hydrochloridová zlúčenina a spôsob jej prípravy
CA2390934C (en) * 1999-11-11 2008-07-15 Nissan Chemical Industries, Ltd. Process for producing benzylamine compound
HUP0401735A3 (en) 2001-10-22 2005-06-28 Pfizer Prod Inc Piperazine derivatives with ccr1 receptor antagonist activity and pharmaceutical compositions containing them
US20060080140A1 (en) * 2004-02-09 2006-04-13 Epic Systems Corporation System and method for providing a clinical summary of patient information in various health care settings
WO2010099388A1 (en) * 2009-02-27 2010-09-02 Indigo Pharmaceuticals Combinational use of a pde3 inhibitor and other agents
CN116768868B (zh) * 2023-08-15 2023-12-08 云南省药物研究所 一种哒嗪酮硫代衍生物及其制备方法和应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0186817B1 (de) * 1984-12-10 1989-08-02 Nissan Chemical Industries Ltd. 3(2H)Pyridazinon, Verfahren zu seiner Herstellung und dieses enthaltendes anti-allergisches Mittel
JPH0641454B2 (ja) * 1985-02-27 1994-06-01 日産化学工業株式会社 ピリダジノン誘導体
EP0201765B1 (de) * 1985-04-27 1991-09-18 Nissan Chemical Industries Ltd. 3(2H) Pyridazinone, Verfahren zu ihrer Herstellung und diese enthaltende anti-allergische Mittel
HU198696B (en) * 1987-01-20 1989-11-28 Nissan Chemical Ind Ltd Process for producing 3/2h/-pyridazinon derivatives and pharmaceutical compositions containing them as active components
JPH02256668A (ja) * 1988-12-20 1990-10-17 Nissan Chem Ind Ltd ピリダジノン誘導体
RU2054004C1 (ru) * 1990-04-25 1996-02-10 Ниссан Кемикал Индастриз Лтд. Производные 3(2н)-пиридазинона или их фармацевтически приемлемые соли и фармацевтическая композиция на их основе
CN1049892C (zh) * 1994-01-25 2000-03-01 日产化学工业株式会社 哒嗪酮衍生物及其盐,其制造方法,及抗血小板医药组合物

Also Published As

Publication number Publication date
RU2138486C1 (ru) 1999-09-27
CZ329995A3 (en) 1996-04-17
TW408114B (en) 2000-10-11
CA2166326C (en) 2005-02-01
ES2124413T3 (es) 1999-02-01
US5929074A (en) 1999-07-27
SK162495A3 (en) 1996-11-06
CN1126470A (zh) 1996-07-10
DE69414112T2 (de) 1999-03-11
CA2166326A1 (en) 1995-01-12
WO1995001343A1 (en) 1995-01-12
FI956300A0 (fi) 1995-12-28
NO955328L (no) 1996-02-28
FI113963B (fi) 2004-07-15
IL110040A0 (en) 1994-10-07
HUT73483A (en) 1996-08-28
HU9503807D0 (en) 1996-02-28
SK280786B6 (sk) 2000-07-11
EP0706517B1 (de) 1998-10-21
AU6983394A (en) 1995-01-24
UA34481C2 (uk) 2001-03-15
RO114791B1 (ro) 1999-07-30
KR100255416B1 (ko) 2000-05-01
EP0706517A1 (de) 1996-04-17
NO306675B1 (no) 1999-12-06
HU221009B1 (hu) 2002-07-29
KR960703401A (ko) 1996-08-17
FI956300A (fi) 1995-12-28
NO955328D0 (no) 1995-12-28
CZ289231B6 (cs) 2001-12-12
ATE172454T1 (de) 1998-11-15
US5728702A (en) 1998-03-17
DK0706517T3 (da) 1999-06-28
NZ267510A (en) 1996-10-28
IL110040A (en) 2000-07-16
AU676341B2 (en) 1997-03-06
CN1044906C (zh) 1999-09-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee