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IE831445L - Process for the production of 1-ethoxycarbonyloxyethyl ester¹of 6-(d-(-)-ó-amino-ó-phenylacetamido) penicillanic acid - Google Patents

Process for the production of 1-ethoxycarbonyloxyethyl ester¹of 6-(d-(-)-ó-amino-ó-phenylacetamido) penicillanic acid

Info

Publication number
IE831445L
IE831445L IE831445A IE144583A IE831445L IE 831445 L IE831445 L IE 831445L IE 831445 A IE831445 A IE 831445A IE 144583 A IE144583 A IE 144583A IE 831445 L IE831445 L IE 831445L
Authority
IE
Ireland
Prior art keywords
group
amino
penicillanic acid
ester1of
phenylacetamido
Prior art date
Application number
IE831445A
Other versions
IE56712B1 (en
Original Assignee
Astra Laekemedel Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT22141/82A external-priority patent/IT1190897B/en
Priority claimed from GB838300331A external-priority patent/GB8300331D0/en
Application filed by Astra Laekemedel Ab filed Critical Astra Laekemedel Ab
Priority to IE1360/91A priority Critical patent/IE56713B1/en
Publication of IE831445L publication Critical patent/IE831445L/en
Publication of IE56712B1 publication Critical patent/IE56712B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C68/00—Preparation of esters of carbonic or haloformic acids
    • C07C68/02—Preparation of esters of carbonic or haloformic acids from phosgene or haloformates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/96—Esters of carbonic or haloformic acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

A compound of formula (IV> <IMAGE> wherein R<1> represents a C1-4 alkyl group, a substituted or unsubstituted aryl group or aralkyl group; R<2> represents hydrogen, a C1-4 alkyl group, a substituted or unsubstituted aryl group or an aralkyl group; R<3> represents a C1-4 alkyl group, a substituted or unsubstituted aryl group, an arylkyl group, a C1-4 alkoxy group, an aryloxy group or an amino group; is a useful intermediate in the manufacture of the corresponding unprotected penicillanic acid. [GB2168050A]
IE1445/83A 1982-06-29 1983-06-20 Process for the production of 1-ethoxycarbonyloxyethyl ester of 6-(d-(-)-alpha-amino-alpha-phenylacetamido)penicillanic acid IE56712B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IE1360/91A IE56713B1 (en) 1982-06-29 1983-06-20 Alpha-bromodiethylcarbonate and its use in the preparation of antibiotics

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
IT22141/82A IT1190897B (en) 1982-06-29 1982-06-29 PROCEDURE FOR THE PREPARATION OF THE 1-ETHOXYCARBONYLOXYETHYL ACID ACID 6- (D (-) - ALPHA AMINOALPHA-PHENYLACETAMIDE) -PENICILLANIC
GB8226751 1982-09-20
GB8228622 1982-10-06
GB8232629 1982-11-16
GB838300331A GB8300331D0 (en) 1983-01-07 1983-01-07 Preparation of bromo carbonates

Publications (2)

Publication Number Publication Date
IE831445L true IE831445L (en) 1983-12-29
IE56712B1 IE56712B1 (en) 1991-11-20

Family

ID=27516485

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1445/83A IE56712B1 (en) 1982-06-29 1983-06-20 Process for the production of 1-ethoxycarbonyloxyethyl ester of 6-(d-(-)-alpha-amino-alpha-phenylacetamido)penicillanic acid

Country Status (23)

Country Link
JP (2) JPH0819052B2 (en)
AT (1) AT383128B (en)
AU (1) AU566803B2 (en)
BG (3) BG37527A3 (en)
CH (2) CH657620B (en)
CY (2) CY1520A (en)
DD (1) DD211561A5 (en)
DE (2) DE3348299C2 (en)
DK (3) DK160039C (en)
FI (1) FI79115C (en)
FR (1) FR2543957B1 (en)
GB (3) GB2168050A (en)
GR (1) GR78585B (en)
HU (1) HU191534B (en)
IE (1) IE56712B1 (en)
IL (1) IL68992A (en)
IS (1) IS1361B6 (en)
NL (1) NL194081C (en)
NO (3) NO157696C (en)
NZ (1) NZ204736A (en)
PT (1) PT76944B (en)
SE (2) SE454879B (en)
YU (2) YU43926B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2573756B1 (en) * 1984-11-23 1987-01-16 Poudres & Explosifs Ste Nale PROCESS FOR THE PREPARATION OF BROMO-1 ETHYL AND HYDROCARBYL CARBONATES AND NOVEL BROMO-1 ETHYL AND HYDROCARBYL CARBONATES

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH516593A (en) * 1967-09-29 1971-12-15 Leo Pharm Prod Ltd Alpha amino-benzyl penicillins - useful as oral antibiotics
US3873521A (en) * 1970-09-17 1975-03-25 Astra Laekemedel Ab Esters of {60 -amino penicillins
IE35648B1 (en) * 1970-09-25 1976-04-14 Beecham Group Ltd Penicillins
DE2161420A1 (en) * 1970-12-30 1972-07-27 Toyama Chemical Co. Ltd., Tokio Penicillin derivatives and processes for their preparation
DE2228670A1 (en) * 1971-06-15 1973-01-11 Yamanouchi Pharma Co Ltd NEW OXYMETHYLESTER DERIVATIVES OF PENICILLIN AND CEPHALOSPORIN
NZ169577A (en) * 1972-02-15 1984-09-28 Ayerst Mckenna & Harrison Preparation of lh-and fsh-releasing hormone,intermediates,and pharmaceutical compositions
GB1426869A (en) * 1972-03-13 1976-03-03 Astra Laekemedel Ab Penicillins
GB1425571A (en) * 1972-03-13 1976-02-18 Astra Laekemedel Ab Penicillins and cephaosporins
GB1426717A (en) * 1972-03-13 1976-03-03 Astra Laekemedel Ab Penicillins
SE397981B (en) * 1973-02-19 1977-11-28 Astra Laekemedel Ab NEW TETRAALKYLAMMONIUM SALTS OF 6-AMINOPENICILLANIC ACID AND OF BENZYLPENICILLIN INTENDED TO BE USED AS INTERMEDIATE PRODUCTS IN THE PREPARATION OF CERTAIN ESTERS OF 6-AMINOPENICILLANIC ACID AND OF BENZYLPENIC
GB1565656A (en) * 1975-12-13 1980-04-23 Beecham Group Ltd Preparation of substituted penicillin acid esters
GB1598568A (en) * 1977-04-19 1981-09-23 Glaxo Lab Ltd Esters of(6r,7r)-3-carbamoyloxymethyl-7-((z)-2-(fur-2-yl)-2-methoxyiminoacetamido)-ceph-3-em-4-carboxylic acid
JPS5444694A (en) * 1977-09-06 1979-04-09 Kou Kamata Aminobenzylpenicillin derivative
DK299083A (en) * 1982-06-30 1983-12-31 Glaxo Group Ltd METHOD FOR MAKING CEPHALOSPOR COMPOUNDS
ATE43833T1 (en) * 1982-11-04 1989-06-15 Astra Laekemedel Ab PROCESS FOR PREPARING THE 1'ETHOXYCARBONYLOXYETHYLESTER OF BENZYLPENICILLIN.

Also Published As

Publication number Publication date
DK159821B (en) 1990-12-10
BG37527A3 (en) 1985-06-14
FR2543957B1 (en) 1986-10-24
GB2168699A (en) 1986-06-25
NO157696C (en) 1988-05-04
DK159821C (en) 1991-04-29
GB2168699B (en) 1987-04-15
NZ204736A (en) 1986-11-12
NO851254L (en) 1983-12-30
AT383128B (en) 1987-05-25
GB8522827D0 (en) 1985-10-23
GB2169287A (en) 1986-07-09
DK105990A (en) 1990-04-30
DK160039B (en) 1991-01-21
AU1632883A (en) 1984-01-05
NL8302286A (en) 1984-01-16
FI832363A0 (en) 1983-06-28
DK296683D0 (en) 1983-06-28
NL194081C (en) 2001-06-05
NO851255L (en) 1983-12-30
NL194081B (en) 2001-02-01
DK106090A (en) 1990-04-30
JPH0717918A (en) 1995-01-20
CH657620B (en) 1986-09-15
YU21886A (en) 1987-10-31
PT76944B (en) 1986-04-09
AU566803B2 (en) 1987-10-29
JPH0819052B2 (en) 1996-02-28
DK167807B1 (en) 1993-12-20
JPH0543583A (en) 1993-02-23
SE454879B (en) 1988-06-06
JPH0730082B2 (en) 1995-04-05
NO832351L (en) 1983-12-30
FI79115C (en) 1989-11-10
DK296683A (en) 1983-12-30
DE3322783C2 (en) 1991-01-31
DE3348299C2 (en) 1990-12-20
BG38336A3 (en) 1985-11-15
DD211561A5 (en) 1984-07-18
IE56712B1 (en) 1991-11-20
GB2168050A (en) 1986-06-11
PT76944A (en) 1983-07-01
SE9100548D0 (en) 1991-02-26
SE8303414L (en) 1983-12-30
FI832363L (en) 1983-12-30
CY1519A (en) 1990-11-16
DK105990D0 (en) 1990-04-30
YU141583A (en) 1986-06-30
CY1520A (en) 1990-11-16
DK106090D0 (en) 1990-04-30
FR2543957A1 (en) 1984-10-12
NO157696B (en) 1988-01-25
DK160039C (en) 1991-06-10
YU43926B (en) 1989-12-31
GB2169287B (en) 1987-04-08
HU191534B (en) 1987-03-30
GB8528958D0 (en) 1986-01-02
IL68992A (en) 1991-06-10
IS1361B6 (en) 1989-05-25
SE8303414D0 (en) 1983-06-15
ATA238483A (en) 1986-10-15
GR78585B (en) 1984-09-27
CH656377A5 (en) 1986-06-30
GB8522826D0 (en) 1985-10-23
BG38335A3 (en) 1985-11-15
SE503843C2 (en) 1996-09-16
IS2825A7 (en) 1984-07-08
SE9100548L (en) 1991-02-26
DE3322783A1 (en) 1984-02-09
YU43693B (en) 1989-10-31
FI79115B (en) 1989-07-31

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