DK159821C - METHOD FOR PREPARING THE 1-AETOXY CARBONYLOXYA ETHYL ESTER OF 6- (D - (-) - ALFA-AMINO-ALFA-PHENYLACETAMIDO) -PENICILLANIC ACID - Google Patents

METHOD FOR PREPARING THE 1-AETOXY CARBONYLOXYA ETHYL ESTER OF 6- (D - (-) - ALFA-AMINO-ALFA-PHENYLACETAMIDO) -PENICILLANIC ACID

Info

Publication number: DK159821C
Authority: DK; Denmark
Prior art keywords: alfa; carbonyloxya; aetoxy; phenylacetamido; amino
Prior art date: 1982-06-29

Application number

DK105990A

Other languages

Danish (da)

Other versions

DK159821B (en

DK105990D0 (en

DK105990A (en

Inventor

Luigi Ratti

Derek Reginald Palmer

Robert Graham Tyson

Original Assignee

Astra Laekemedel Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-06-29

Filing date

1990-04-30

Publication date

1991-04-29

1982-06-29 Priority claimed from IT22141/82A external-priority patent/IT1190897B/en

1983-01-07 Priority claimed from GB838300331A external-priority patent/GB8300331D0/en

1990-04-30 Application filed by Astra Laekemedel Ab filed Critical Astra Laekemedel Ab

1990-04-30 Publication of DK105990D0 publication Critical patent/DK105990D0/en

1990-04-30 Publication of DK105990A publication Critical patent/DK105990A/en

1990-12-10 Publication of DK159821B publication Critical patent/DK159821B/en

1991-04-29 Application granted granted Critical

1991-04-29 Publication of DK159821C publication Critical patent/DK159821C/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C68/00—Preparation of esters of carbonic or haloformic acids
- C07C68/02—Preparation of esters of carbonic or haloformic acids from phosgene or haloformates
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/96—Esters of carbonic or haloformic acids
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Communicable Diseases (AREA)
Animal Behavior & Ethology (AREA)
Oncology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Cephalosporin Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Plural Heterocyclic Compounds (AREA)

DK105990A 1982-06-29 1990-04-30 METHOD FOR PREPARING THE 1-AETOXY CARBONYLOXYA ETHYL ESTER OF 6- (D - (-) - ALFA-AMINO-ALFA-PHENYLACETAMIDO) -PENICILLANIC ACID DK159821C (en)

Applications Claiming Priority (10)

Application Number	Priority Date	Filing Date	Title
IT2214182		1982-06-29
IT22141/82A IT1190897B (en)	1982-06-29	1982-06-29	PROCEDURE FOR THE PREPARATION OF THE 1-ETHOXYCARBONYLOXYETHYL ACID ACID 6- (D (-) - ALPHA AMINOALPHA-PHENYLACETAMIDE) -PENICILLANIC
GB8226751		1982-09-20
GB8226751		1982-09-20
GB8228622		1982-10-06
GB8228622		1982-10-06
GB8232629		1982-11-16
GB8232629		1982-11-16
GB838300331A GB8300331D0 (en)	1983-01-07	1983-01-07	Preparation of bromo carbonates
GB8300331		1983-01-07

Publications (4)

Publication Number	Publication Date
DK105990D0 DK105990D0 (en)	1990-04-30
DK105990A DK105990A (en)	1990-04-30
DK159821B DK159821B (en)	1990-12-10
DK159821C true DK159821C (en)	1991-04-29

Family

ID=27516485

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
DK296683A DK160039C (en)	1982-06-29	1983-06-28	THE COMPOUND ALFA-BROMIDAETHYL CARBONATE AND USE OF ALFA-BROMIDAETHYL CARBONATE IN THE PREPARATION OF THE AETOXYCARBONYLOXYAETHYL ESTATE OF PENICILLIN G
DK105990A DK159821C (en)	1982-06-29	1990-04-30	METHOD FOR PREPARING THE 1-AETOXY CARBONYLOXYA ETHYL ESTER OF 6- (D - (-) - ALFA-AMINO-ALFA-PHENYLACETAMIDO) -PENICILLANIC ACID
DK106090A DK167807B1 (en)	1982-06-29	1990-04-30	METHOD FOR PREPARING THE 1-ETHOXYCARBONYLOXYETHYL ESTER OF 6- (D - (-) - ALFA-AMINO-ALFA-PHENYLACETAMIDO) -PENICILLANIC ACID

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
DK296683A DK160039C (en)	1982-06-29	1983-06-28	THE COMPOUND ALFA-BROMIDAETHYL CARBONATE AND USE OF ALFA-BROMIDAETHYL CARBONATE IN THE PREPARATION OF THE AETOXYCARBONYLOXYAETHYL ESTATE OF PENICILLIN G

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
DK106090A DK167807B1 (en)	1982-06-29	1990-04-30	METHOD FOR PREPARING THE 1-ETHOXYCARBONYLOXYETHYL ESTER OF 6- (D - (-) - ALFA-AMINO-ALFA-PHENYLACETAMIDO) -PENICILLANIC ACID

Country Status (23)

Country	Link
JP (2)	JPH0819052B2 (en)
AT (1)	AT383128B (en)
AU (1)	AU566803B2 (en)
BG (3)	BG37527A3 (en)
CH (2)	CH656377A5 (en)
CY (2)	CY1519A (en)
DD (1)	DD211561A5 (en)
DE (2)	DE3322783A1 (en)
DK (3)	DK160039C (en)
FI (1)	FI79115C (en)
FR (1)	FR2543957B1 (en)
GB (3)	GB2168050A (en)
GR (1)	GR78585B (en)
HU (1)	HU191534B (en)
IE (1)	IE56712B1 (en)
IL (1)	IL68992A (en)
IS (1)	IS1361B6 (en)
NL (1)	NL194081C (en)
NO (3)	NO157696C (en)
NZ (1)	NZ204736A (en)
PT (1)	PT76944B (en)
SE (2)	SE454879B (en)
YU (2)	YU43926B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2573756B1 (en) *	1984-11-23	1987-01-16	Poudres & Explosifs Ste Nale	PROCESS FOR THE PREPARATION OF BROMO-1 ETHYL AND HYDROCARBYL CARBONATES AND NOVEL BROMO-1 ETHYL AND HYDROCARBYL CARBONATES

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH516593A (en) *	1967-09-29	1971-12-15	Leo Pharm Prod Ltd	Alpha amino-benzyl penicillins - useful as oral antibiotics
US3873521A (en) *	1970-09-17	1975-03-25	Astra Laekemedel Ab	Esters of {60 -amino penicillins
IE35648B1 (en) *	1970-09-25	1976-04-14	Beecham Group Ltd	Penicillins
DE2161420A1 (en) *	1970-12-30	1972-07-27	Toyama Chemical Co. Ltd., Tokio	Penicillin derivatives and processes for their preparation
DE2228670A1 (en) *	1971-06-15	1973-01-11	Yamanouchi Pharma Co Ltd	NEW OXYMETHYLESTER DERIVATIVES OF PENICILLIN AND CEPHALOSPORIN
NZ169577A (en) *	1972-02-15	1984-09-28	Ayerst Mckenna & Harrison	Preparation of lh-and fsh-releasing hormone,intermediates,and pharmaceutical compositions
GB1425571A (en) *	1972-03-13	1976-02-18	Astra Laekemedel Ab	Penicillins and cephaosporins
GB1426869A (en) *	1972-03-13	1976-03-03	Astra Laekemedel Ab	Penicillins
GB1426717A (en) *	1972-03-13	1976-03-03	Astra Laekemedel Ab	Penicillins
SE397981B (en) *	1973-02-19	1977-11-28	Astra Laekemedel Ab	NEW TETRAALKYLAMMONIUM SALTS OF 6-AMINOPENICILLANIC ACID AND OF BENZYLPENICILLIN INTENDED TO BE USED AS INTERMEDIATE PRODUCTS IN THE PREPARATION OF CERTAIN ESTERS OF 6-AMINOPENICILLANIC ACID AND OF BENZYLPENIC
GB1565656A (en) *	1975-12-13	1980-04-23	Beecham Group Ltd	Preparation of substituted penicillin acid esters
GB1598568A (en) *	1977-04-19	1981-09-23	Glaxo Lab Ltd	Esters of(6r,7r)-3-carbamoyloxymethyl-7-((z)-2-(fur-2-yl)-2-methoxyiminoacetamido)-ceph-3-em-4-carboxylic acid
JPS5444694A (en) *	1977-09-06	1979-04-09	Kou Kamata	Aminobenzylpenicillin derivative
SE8303727L (en) *	1982-06-30	1984-02-03	Glaxo Group Ltd	cephalosporin antibiotics
ATE43833T1 (en) *	1982-11-04	1989-06-15	Astra Laekemedel Ab	PROCESS FOR PREPARING THE 1'ETHOXYCARBONYLOXYETHYLESTER OF BENZYLPENICILLIN.

1983
- 1983-06-15 IL IL68992A patent/IL68992A/en not_active IP Right Cessation
- 1983-06-15 SE SE8303414A patent/SE454879B/en not_active IP Right Cessation
- 1983-06-20 IE IE1445/83A patent/IE56712B1/en not_active IP Right Cessation
- 1983-06-24 DE DE3322783A patent/DE3322783A1/en active Granted
- 1983-06-24 DE DE3348299A patent/DE3348299C2/de not_active Expired - Lifetime
- 1983-06-27 GB GB08528958A patent/GB2168050A/en not_active Withdrawn
- 1983-06-28 NO NO832351A patent/NO157696C/en not_active IP Right Cessation
- 1983-06-28 BG BG061516A patent/BG37527A3/en unknown
- 1983-06-28 AU AU16328/83A patent/AU566803B2/en not_active Expired
- 1983-06-28 NZ NZ204736A patent/NZ204736A/en unknown
- 1983-06-28 CH CH3540/83A patent/CH656377A5/en not_active IP Right Cessation
- 1983-06-28 CH CH527585A patent/CH657620B/de not_active IP Right Cessation
- 1983-06-28 FI FI832363A patent/FI79115C/en not_active IP Right Cessation
- 1983-06-28 GR GR71790A patent/GR78585B/el unknown
- 1983-06-28 PT PT76944A patent/PT76944B/en unknown
- 1983-06-28 DK DK296683A patent/DK160039C/en not_active IP Right Cessation
- 1983-06-28 HU HU832325A patent/HU191534B/en unknown
- 1983-06-28 BG BG068053A patent/BG38336A3/en unknown
- 1983-06-28 NL NL8302286A patent/NL194081C/en not_active IP Right Cessation
- 1983-06-28 BG BG068052A patent/BG38335A3/en unknown
- 1983-06-29 YU YU1415/83A patent/YU43926B/en unknown
- 1983-06-29 DD DD83252531A patent/DD211561A5/en unknown
- 1983-06-29 AT AT0238483A patent/AT383128B/en not_active IP Right Cessation
- 1983-06-29 IS IS2825A patent/IS1361B6/en unknown
- 1983-12-30 FR FR8321138A patent/FR2543957B1/en not_active Expired
1985
- 1985-03-28 NO NO851254A patent/NO851254L/en unknown
- 1985-03-28 NO NO851255A patent/NO851255L/en unknown
- 1985-09-16 GB GB08522827A patent/GB2169287B/en not_active Expired
- 1985-09-16 GB GB08522826A patent/GB2168699B/en not_active Expired
1986
- 1986-02-14 YU YU218/86A patent/YU43693B/en unknown
1990
- 1990-04-30 DK DK105990A patent/DK159821C/en not_active IP Right Cessation
- 1990-04-30 DK DK106090A patent/DK167807B1/en not_active IP Right Cessation
- 1990-11-16 CY CY1519A patent/CY1519A/en unknown
- 1990-11-16 CY CY1520A patent/CY1520A/en unknown
1991
- 1991-02-26 SE SE9100548A patent/SE503843C2/en not_active IP Right Cessation
- 1991-04-30 JP JP3124442A patent/JPH0819052B2/en not_active Expired - Lifetime
- 1991-04-30 JP JP3124441A patent/JPH0730082B2/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
NO157696C (en)	1988-05-04
DE3348299C2 (en)	1990-12-20
SE8303414D0 (en)	1983-06-15
FI832363A0 (en)	1983-06-28
AU1632883A (en)	1984-01-05
FI832363L (en)	1983-12-30
FI79115C (en)	1989-11-10
DK167807B1 (en)	1993-12-20
DE3322783C2 (en)	1991-01-31
YU43926B (en)	1989-12-31
GB8522826D0 (en)	1985-10-23
GB2168699A (en)	1986-06-25
NO832351L (en)	1983-12-30
SE9100548L (en)	1991-02-26
YU43693B (en)	1989-10-31
DK159821B (en)	1990-12-10
IE831445L (en)	1983-12-29
DK105990D0 (en)	1990-04-30
GB2169287A (en)	1986-07-09
NL8302286A (en)	1984-01-16
JPH0543583A (en)	1993-02-23
SE454879B (en)	1988-06-06
FI79115B (en)	1989-07-31
DK106090A (en)	1990-04-30
HU191534B (en)	1987-03-30
SE503843C2 (en)	1996-09-16
DK296683A (en)	1983-12-30
IS1361B6 (en)	1989-05-25
IE56712B1 (en)	1991-11-20
IS2825A7 (en)	1984-07-08
IL68992A (en)	1991-06-10
FR2543957A1 (en)	1984-10-12
CY1520A (en)	1990-11-16
NO851255L (en)	1983-12-30
DD211561A5 (en)	1984-07-18
DK296683D0 (en)	1983-06-28
NL194081C (en)	2001-06-05
AT383128B (en)	1987-05-25
GB2168050A (en)	1986-06-11
JPH0730082B2 (en)	1995-04-05
AU566803B2 (en)	1987-10-29
NO157696B (en)	1988-01-25
GB2168699B (en)	1987-04-15
GB8528958D0 (en)	1986-01-02
DK160039C (en)	1991-06-10
JPH0717918A (en)	1995-01-20
DK106090D0 (en)	1990-04-30
SE8303414L (en)	1983-12-30
BG38335A3 (en)	1985-11-15
SE9100548D0 (en)	1991-02-26
DE3322783A1 (en)	1984-02-09
GB8522827D0 (en)	1985-10-23
GB2169287B (en)	1987-04-08
CY1519A (en)	1990-11-16
FR2543957B1 (en)	1986-10-24
NL194081B (en)	2001-02-01
NO851254L (en)	1983-12-30
YU141583A (en)	1986-06-30
ATA238483A (en)	1986-10-15
JPH0819052B2 (en)	1996-02-28
DK105990A (en)	1990-04-30
DK160039B (en)	1991-01-21
NZ204736A (en)	1986-11-12
GR78585B (en)	1984-09-27
CH656377A5 (en)	1986-06-30
CH657620B (en)	1986-09-15
BG38336A3 (en)	1985-11-15
PT76944A (en)	1983-07-01
PT76944B (en)	1986-04-09
YU21886A (en)	1987-10-31
BG37527A3 (en)	1985-06-14

Publication	Publication Date	Title
DK336783D0 (en)	1983-07-22	METHOD OF PREPARING METHYLENDIPHOSPHONIC ACID DERIVATIVES
RO86355A (en)	1985-03-15	PROCESS FOR THE PREPARATION OF (S) -EPEMER OF THE ACID ESTER 7-BETA-MALONAMIDE-7-ALFA-METHO-3-TETRAZOLYL-TOMETHYL-1-DETHALYL-
DK156828C (en)	1990-02-19	PROCEDURE FOR PREPARING CYCLOPROPANCARBOXYL ACID ESTER DERIVATIVES
DK265783A (en)	1983-12-15	METHOD OF PREPARING VINYL CARBOXYL ACID DERIVATIVES
DK159109C (en)	1991-02-18	METHOD OF PREPARING L-ASCORBIC ACID
DK357782A (en)	1983-02-11	METHOD OF PREPARING TETRAHYDROFURANCARBOXYL ACID DERIVATIVES
DK159122C (en)	1991-02-11	METHOD OF PREPARING 2-KETO-L-GULONIC ACID
DK161106C (en)	1991-11-11	METHOD OF PREPARING 2-KETO-L-GULONIC ACID
DK98684D0 (en)	1984-02-24	PROCEDURE FOR THE PREPARATION OF FATIC ACID ESTERS OF ASCORBIC ACID
DK157673C (en)	1990-07-16	METHOD OF ANALOGY FOR THE PREPARATION OF PHENYLALIPHATIC CARBOXYLIC ACID DERIVATIVES
DK554481A (en)	1982-06-16	METHOD OF PREPARING CEPHALOSPORANIC ACID DERIVATIVES
DK262982A (en)	1982-12-13	PROCEDURE FOR THE PREPARATION OF APOVINCAMIC ACID ESTERS
DK157677C (en)	1990-06-18	PROCEDURE FOR PREPARING CYCLOPROPANCARBOXYL ACID ESTER DERIVATIVES
DK354680A (en)	1981-02-19	METHOD OF PREPARING SUBSTITUTED (CYCLO) ALKANCARBOXYLIC ACID (ALFA-CYANO-3-PHENOXY-BENZYL) ESTERS
DK408782A (en)	1983-03-31	PROCEDURE FOR THE PREPARATION OF ANTHRANIC ACID ESTERS
DK159821C (en)	1991-04-29	METHOD FOR PREPARING THE 1-AETOXY CARBONYLOXYA ETHYL ESTER OF 6- (D - (-) - ALFA-AMINO-ALFA-PHENYLACETAMIDO) -PENICILLANIC ACID
DK139983A (en)	1984-06-04	METHOD OF PREPARING 2-THIOPHENIC ACETIC ACID DERIVATIVES
DK157613C (en)	1990-06-11	PROCEDURE FOR PREPARING CYCLOPROPANCARBOXYL ACID ESTER DERIVATIVES
DK488088D0 (en)	1988-09-02	METHOD OF PREPARING 1-ARYL-3-PYRAZOL-3-CARBOXYL ACID ESTERS
DK467381A (en)	1982-04-24	METHOD OF PREPARING CHLOR-FLUORALKENYL-SUBSTITUTED CYCLOPROPANCARBOXYL ACID ESTERS
DK153760C (en)	1989-01-09	METHOD OF ANALOGUE FOR THE PREPARATION OF ESTERS OF 2-THENOYLMERCAPTOPROPIONYLGYLINE
DK20782A (en)	1982-07-20	METHOD OF PREPARING CEPHALOSPORANIC ACID DERIVATIVES
DK151020C (en)	1988-02-29	PROCEDURE FOR THE PREPARATION OF APOVINCAMIC ACID ESTERS
DK196883D0 (en)	1983-05-03	PROCEDURE FOR THE PREPARATION OF CYANHYDRINE CARBOXYL ACID ESTERS
DK179183D0 (en)	1983-04-22	METHOD OF PREPARING HYDROXYMETHYLBUTIC ACIDS

Legal Events

Date	Code	Title	Description
2003-07-14	PUP	Patent expired