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HUE064187T2 - Eljárás immunterápiára alkalmas allogén és immunszupresszív-rezisztens T-sejt módosítására - Google Patents

Eljárás immunterápiára alkalmas allogén és immunszupresszív-rezisztens T-sejt módosítására

Info

Publication number
HUE064187T2
HUE064187T2 HUE13731522A HUE13731522A HUE064187T2 HU E064187 T2 HUE064187 T2 HU E064187T2 HU E13731522 A HUE13731522 A HU E13731522A HU E13731522 A HUE13731522 A HU E13731522A HU E064187 T2 HUE064187 T2 HU E064187T2
Authority
HU
Hungary
Prior art keywords
immunotherapy
cell
methods
engineering allogeneic
immunosuppressive resistant
Prior art date
Application number
HUE13731522A
Other languages
English (en)
Inventor
Roman Galetto
Agnes Gouble
Stephanie Grosse
Cecile Mannioui
Laurent Poirot
Andrew Scharenberg
Julianne Smith
Original Assignee
Cellectis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48579464&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUE064187(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cellectis filed Critical Cellectis
Publication of HUE064187T2 publication Critical patent/HUE064187T2/hu

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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • C—CHEMISTRY; METALLURGY
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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    • A61K39/46—Cellular immunotherapy
    • A61K39/461—Cellular immunotherapy characterised by the cell type used
    • A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
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    • A—HUMAN NECESSITIES
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    • A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70517—CD8
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70521—CD28, CD152
    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
    • C—CHEMISTRY; METALLURGY
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    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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    • C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
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    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
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    • C12N2501/50—Cell markers; Cell surface determinants
    • C12N2501/51—B7 molecules, e.g. CD80, CD86, CD28 (ligand), CD152 (ligand)
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  • Health & Medical Sciences (AREA)
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  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
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  • Public Health (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Epidemiology (AREA)
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  • Hematology (AREA)
  • General Engineering & Computer Science (AREA)
  • Oncology (AREA)
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  • Communicable Diseases (AREA)
  • Developmental Biology & Embryology (AREA)
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HUE13731522A 2012-05-25 2013-05-13 Eljárás immunterápiára alkalmas allogén és immunszupresszív-rezisztens T-sejt módosítására HUE064187T2 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261651933P 2012-05-25 2012-05-25
US201261696612P 2012-09-04 2012-09-04

Publications (1)

Publication Number Publication Date
HUE064187T2 true HUE064187T2 (hu) 2024-02-28

Family

ID=48579464

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE13731522A HUE064187T2 (hu) 2012-05-25 2013-05-13 Eljárás immunterápiára alkalmas allogén és immunszupresszív-rezisztens T-sejt módosítására

Country Status (25)

Country Link
US (15) US10426795B2 (hu)
EP (6) EP3279315A3 (hu)
JP (5) JP6463671B2 (hu)
KR (2) KR102247979B1 (hu)
CN (3) CN108998418A (hu)
AR (1) AR096274A1 (hu)
AU (5) AU2013266734B2 (hu)
BR (1) BR112014029417B1 (hu)
CA (3) CA2874611C (hu)
DK (1) DK2855667T5 (hu)
EA (1) EA201492222A1 (hu)
ES (1) ES2962571T3 (hu)
HK (2) HK1208879A1 (hu)
HU (1) HUE064187T2 (hu)
IN (1) IN2014DN10991A (hu)
MA (1) MA37681B2 (hu)
MX (1) MX370265B (hu)
MY (1) MY180127A (hu)
NZ (1) NZ703281A (hu)
PL (1) PL2855667T3 (hu)
PT (1) PT2855667T (hu)
SG (2) SG10201806573TA (hu)
UA (1) UA118652C2 (hu)
WO (2) WO2013176916A1 (hu)
ZA (1) ZA201409536B (hu)

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US10967298B2 (en) 2012-03-15 2021-04-06 Flodesign Sonics, Inc. Driver and control for variable impedence load
US10704021B2 (en) 2012-03-15 2020-07-07 Flodesign Sonics, Inc. Acoustic perfusion devices
US9950282B2 (en) 2012-03-15 2018-04-24 Flodesign Sonics, Inc. Electronic configuration and control for acoustic standing wave generation
US9458450B2 (en) 2012-03-15 2016-10-04 Flodesign Sonics, Inc. Acoustophoretic separation technology using multi-dimensional standing waves
US20150017136A1 (en) * 2013-07-15 2015-01-15 Cellectis Methods for engineering allogeneic and highly active t cell for immunotherapy
DK2855667T5 (da) 2012-05-25 2024-10-14 Cellectis Fremgangsmåder til manipulation af allogeniske og immunosuppressiv-resistante T-celler til immunterapi
DK2906684T3 (da) * 2012-10-10 2020-09-28 Sangamo Therapeutics Inc T-celle-modificerende forbindelser og anvendelser deraf
KR20210147101A (ko) 2013-02-15 2021-12-06 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 키메라 항원 수용체 및 이의 이용 방법
US9499855B2 (en) 2013-03-14 2016-11-22 Elwha Llc Compositions, methods, and computer systems related to making and administering modified T cells
US9587237B2 (en) 2013-03-14 2017-03-07 Elwha Llc Compositions, methods, and computer systems related to making and administering modified T cells
KR20150131218A (ko) * 2013-03-14 2015-11-24 벨리쿰 파마슈티컬스, 인크. T 세포 증식의 제어 방법
JP6005572B2 (ja) * 2013-03-28 2016-10-12 Kddi株式会社 動画像符号化装置、動画像復号装置、動画像符号化方法、動画像復号方法、およびプログラム
PT2981607T (pt) 2013-04-03 2020-11-20 Memorial Sloan Kettering Cancer Center Geração eficaz de células t direcionadas a tumores, derivadas de células estaminais pluripotentes
US20230050345A1 (en) * 2013-05-13 2023-02-16 Cellectis Methods for engineering allogeneic and highly active t cell for immunotheraphy
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EP3279315A2 (en) 2018-02-07
US20160145337A1 (en) 2016-05-26
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DK2855667T3 (da) 2023-10-30
US20240309397A1 (en) 2024-09-19

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