HK95092A - 2-substituted n,n-di-trimethoxybenzoyl piperazines and pharmaceutical uses thereof - Google Patents

2-substituted n,n-di-trimethoxybenzoyl piperazines and pharmaceutical uses thereof

Info

Publication number: HK95092A
Authority: HK; Hong Kong
Prior art keywords: trimethoxybenzoyl; piperazines; substituted; pharmaceutical uses; pharmaceutical
Prior art date: 1989-04-15

Application number

HK950/92A

Other languages

English (en)

Inventor

Pierre Braquet

Eduardo Pirotzky

Jean-Jacques Godfroid

Francoise Heymans

Original Assignee

Scras

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-04-15

Filing date

1992-11-26

Publication date

1992-12-04

1992-11-26 Application filed by Scras filed Critical Scras

1992-12-04 Publication of HK95092A publication Critical patent/HK95092A/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/12—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Pulmonology (AREA)
Immunology (AREA)
Diabetes (AREA)
Hematology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

HK950/92A 1989-04-15 1992-11-26 2-substituted n,n-di-trimethoxybenzoyl piperazines and pharmaceutical uses thereof HK95092A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB898908587A GB8908587D0 (en)	1989-04-15	1989-04-15	New 2-substituted n,n'-ditrimethoxybenzoyl piperazines

Publications (1)

Publication Number	Publication Date
HK95092A true HK95092A (en)	1992-12-04

Family

ID=10655129

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HK950/92A HK95092A (en)	1989-04-15	1992-11-26	2-substituted n,n-di-trimethoxybenzoyl piperazines and pharmaceutical uses thereof

Country Status (32)

Country	Link
US (1)	US5019576A (fi)
JP (1)	JP2633709B2 (fi)
KR (1)	KR900016178A (fi)
AR (1)	AR247736A1 (fi)
AT (1)	AT399337B (fi)
AU (1)	AU631334B2 (fi)
BE (1)	BE1007245A3 (fi)
CA (1)	CA2014521C (fi)
CH (1)	CH681301A5 (fi)
DE (1)	DE4011925A1 (fi)
DK (1)	DK91890A (fi)
DZ (1)	DZ1407A1 (fi)
ES (1)	ES2019554A6 (fi)
FI (1)	FI92058C (fi)
FR (2)	FR2645743B1 (fi)
GB (2)	GB8908587D0 (fi)
GR (1)	GR1000355B (fi)
HK (1)	HK95092A (fi)
IE (1)	IE65058B1 (fi)
IN (1)	IN175799B (fi)
IT (1)	IT1241631B (fi)
LU (1)	LU87719A1 (fi)
MA (1)	MA21805A1 (fi)
NL (1)	NL9000798A (fi)
NO (1)	NO176098C (fi)
NZ (1)	NZ233250A (fi)
OA (1)	OA09446A (fi)
PT (1)	PT93736B (fi)
SE (1)	SE505186C2 (fi)
SG (1)	SG92092G (fi)
TN (1)	TNSN90051A1 (fi)
ZA (1)	ZA902566B (fi)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5344830A (en) *	1992-12-10	1994-09-06	Merck & Co., Inc.	N,N-diacylpiperazine tachykinin antagonists
US5883098A (en) *	1993-11-29	1999-03-16	Fujisawa Pharmaceutical Co., Ltd.	Piperazine derivatives
IL111730A (en) *	1993-11-29	1998-12-06	Fujisawa Pharmaceutical Co	Piperazine derivatives processes for the preparation thereof and pharmaceutical compositions containing the same
US5610165A (en) *	1994-02-17	1997-03-11	Merck & Co., Inc.	N-acylpiperidine tachykinin antagonists
US5795894A (en) *	1995-05-02	1998-08-18	Schering Corporation	Piperazino derivatives as neurokinn antagonists
CZ342397A3 (cs) *	1995-05-02	1998-03-18	Schering Corporation	Piperazinové deriváty jako antagonisté neurokininu
BR9610277A (pt) *	1995-08-31	1999-07-06	Schering Corp	Derivados de piperazino como antagonistas de neurowuinina
US5892039A (en) *	1995-08-31	1999-04-06	Schering Corporation	Piperazino derivatives as neurokinin antagonists
US5869488A (en) *	1996-05-01	1999-02-09	Schering Corporation	Piperazino derivatives as neurokinin antagonists
FR2780649B1 (fr) *	1998-07-06	2001-03-09	Univ Paris Vii Denis Diderot	Derives de la piperazine pour l'inhibition de la replication du virus de l'immunodeficience humaine

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1243991A (en) *	1968-06-10	1971-08-25	Ici Ltd	Piperidine, morpholine and piperazine derivatives
FR2209560A1 (en) *	1972-12-07	1974-07-05	Degussa	N-(Trialkoxyaroyl)-ethylenediamine derivs - useful as cardioactive medicaments, exhibit anti-ischaemic activity comparable to nitroglycerin
IL85700A0 (en) *	1987-03-24	1988-08-31	Takeda Chemical Industries Ltd	1,4-disubstituted piperazine compounds,their production and use
EP0318235A3 (en) *	1987-11-25	1991-05-02	Takeda Chemical Industries, Ltd.	Paf antagonist, 1,4-disubstituted piperazine compounds and production thereof
FI892468A (fi) *	1988-05-23	1989-11-24	Glaxo Group Ltd	Piperazinderivat.
GB8823776D0 (en) *	1988-10-11	1988-11-16	Scras	New 2-methoxycarbonyl sustituted n n'-di-(trimethoxybenzoyl)piperazines
GB8823775D0 (en) *	1988-10-11	1988-11-16	Scras	New 2-carbonyl substituted n n'-di-(trimethoxybenzoyl)piperazines
US4997836A (en) *	1988-11-11	1991-03-05	Takeda Chemical Industries, Ltd.	Trisubstituted piperazine compounds, their production and use

1989
- 1989-04-15 GB GB898908587A patent/GB8908587D0/en active Pending
1990
- 1990-04-03 ZA ZA902566A patent/ZA902566B/xx unknown
- 1990-04-04 GB GB9007612A patent/GB2230262B/en not_active Expired - Lifetime
- 1990-04-05 NL NL9000798A patent/NL9000798A/nl not_active Application Discontinuation
- 1990-04-05 IN IN140DE1990D patent/IN175799B/en unknown
- 1990-04-06 GR GR900100270A patent/GR1000355B/el unknown
- 1990-04-06 SE SE9001269A patent/SE505186C2/sv not_active IP Right Cessation
- 1990-04-09 US US07/506,421 patent/US5019576A/en not_active Expired - Lifetime
- 1990-04-09 NZ NZ233250A patent/NZ233250A/en unknown
- 1990-04-10 CH CH1206/90A patent/CH681301A5/fr not_active IP Right Cessation
- 1990-04-10 NO NO901631A patent/NO176098C/no unknown
- 1990-04-10 MA MA22064A patent/MA21805A1/fr unknown
- 1990-04-10 AR AR90316593A patent/AR247736A1/es active
- 1990-04-10 LU LU87719A patent/LU87719A1/fr unknown
- 1990-04-11 DK DK091890A patent/DK91890A/da unknown
- 1990-04-11 DZ DZ900066A patent/DZ1407A1/fr active
- 1990-04-11 PT PT93736A patent/PT93736B/pt not_active IP Right Cessation
- 1990-04-11 IE IE131490A patent/IE65058B1/en not_active IP Right Cessation
- 1990-04-11 AT AT0086690A patent/AT399337B/de not_active IP Right Cessation
- 1990-04-11 ES ES9001056A patent/ES2019554A6/es not_active Expired - Lifetime
- 1990-04-11 BE BE9000408A patent/BE1007245A3/fr not_active IP Right Cessation
- 1990-04-12 FI FI901883A patent/FI92058C/fi not_active IP Right Cessation
- 1990-04-12 IT IT20020A patent/IT1241631B/it active IP Right Grant
- 1990-04-12 TN TNTNSN90051A patent/TNSN90051A1/fr unknown
- 1990-04-12 DE DE4011925A patent/DE4011925A1/de not_active Ceased
- 1990-04-12 OA OA59775A patent/OA09446A/xx unknown
- 1990-04-12 CA CA002014521A patent/CA2014521C/en not_active Expired - Fee Related
- 1990-04-13 FR FR909004797A patent/FR2645743B1/fr not_active Expired - Lifetime
- 1990-04-13 FR FR909004798A patent/FR2645859B1/fr not_active Expired - Lifetime
- 1990-04-13 JP JP2096620A patent/JP2633709B2/ja not_active Expired - Lifetime
- 1990-04-14 KR KR1019900005198A patent/KR900016178A/ko not_active Application Discontinuation
- 1990-04-17 AU AU53261/90A patent/AU631334B2/en not_active Ceased
1992
- 1992-09-11 SG SG920/92A patent/SG92092G/en unknown
- 1992-11-26 HK HK950/92A patent/HK95092A/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
AR247736A1 (es)	1995-03-31
PT93736A (pt)	1990-11-20
KR900016178A (ko)	1990-11-12
GB9007612D0 (en)	1990-05-30
GB8908587D0 (en)	1989-06-01
CA2014521A1 (en)	1990-10-15
DE4011925A1 (de)	1990-10-18
ES2019554A6 (es)	1991-06-16
AT399337B (de)	1995-04-25
FR2645859A1 (fr)	1990-10-19
FI901883A0 (fi)	1990-04-12
IT1241631B (it)	1994-01-25
GB2230262A (en)	1990-10-17
GR900100270A (en)	1991-09-27
CH681301A5 (fi)	1993-02-26
NO176098B (no)	1994-10-24
US5019576A (en)	1991-05-28
CA2014521C (en)	1997-09-09
SE9001269D0 (sv)	1990-04-06
TNSN90051A1 (fr)	1991-03-05
FI92058C (fi)	1994-09-26
FR2645743B1 (fr)	1992-06-05
SE9001269L (sv)	1990-10-16
FR2645859B1 (fr)	1992-06-05
ZA902566B (en)	1991-01-30
IT9020020A0 (it)	1990-04-12
PT93736B (pt)	1996-09-30
AU5326190A (en)	1990-11-01
NO901631D0 (no)	1990-04-10
ATA86690A (de)	1994-09-15
NZ233250A (en)	1991-03-26
BE1007245A3 (fr)	1995-05-02
JP2633709B2 (ja)	1997-07-23
SG92092G (en)	1992-12-04
SE505186C2 (sv)	1997-07-14
LU87719A1 (fr)	1990-07-24
NO176098C (no)	1995-02-01
GB2230262B (en)	1992-02-26
NO901631L (no)	1990-10-16
IE65058B1 (en)	1995-10-04
JPH02292266A (ja)	1990-12-03
DZ1407A1 (fr)	2004-09-13
MA21805A1 (fr)	1990-12-31
IE901314L (en)	1990-10-15
OA09446A (fr)	1992-10-15
AU631334B2 (en)	1992-11-19
FR2645743A1 (fr)	1990-10-19
NL9000798A (nl)	1990-11-01
IN175799B (fi)	1995-08-26
GR1000355B (el)	1992-06-25
IT9020020A1 (it)	1991-10-12
DK91890A (da)	1990-10-16
FI92058B (fi)	1994-06-15
DK91890D0 (da)	1990-04-11

Publication	Publication Date	Title
HUP9800792A3 (en)	2000-02-28	Benzylpiperidines and piperazines, their use and pharmaceutical compositions containing the same
NZ218089A (en)	1989-03-29	7-piperazinyl, 4-oxoquinolines and pharmaceutical compositions
AR243499A1 (es)	1993-08-31	Un procedimiento para la preparacion de derivados de sulfonanilida.
ZA862351B (en)	1986-11-26	Drug,preparation and use thereof
GB8917687D0 (en)	1989-09-20	Aminopiperazine derivatives,processes for preparation thereof and pharmaceutical composition comprising the same
GB2230262B (en)	1992-02-26	2-substituted n,n-di-trimethoxybenzoyl piperazines and pharmaceutical uses thereof
EP0421436A3 (en)	1992-03-11	Substituted carboxytetrahydroisoquinolines and derivatives thereof having pharmaceutical activity
EP0417751A3 (en)	1991-09-11	New thiazole derivatives, processes for the preparation thereof and pharmaceutical compositon comprising the same
GB9123353D0 (en)	1991-12-18	New mercapto-amide derivatives,processes for the preparation thereof and pharmaceutical composition comprising the same
PH24836A (en)	1990-10-30	Alkyl-substituted n-benzopyranyllactams,their use and pharmaceutical preparations based on these compounds
GB9025509D0 (en)	1991-01-09	New amide derivatives,processes for the preparation thereof and pharmaceutical composition comprising the same
NZ234369A (en)	1991-10-25	6-(naphthalenylethyl)-4-hydroxy-pyran-2-one derivatives and the 3,5-dihydroxyheptanoates; pharmaceutical compositions
IL109527A0 (en)	1994-08-26	Substituted piperazines, their preparation and pharmaceutical compostions containing them
IL93749A0 (en)	1990-12-23	Quinoline derivatives,their preparation and medicaments comprising them
ZA902823B (en)	1991-01-30	Substituted uracils,processes for their preparation and their use against parasitic protozona
AU7057691A (en)	1991-08-21	Piperazine compound, production thereof, and medicinal use thereof
ZA913171B (en)	1992-02-26	1,5-benzothiazepinone derivatives,their preparations and pharmaceutical use
NZ233400A (en)	1991-02-26	1,3-diazine derivatives and pharmaceutical compositions
NZ233129A (en)	1992-03-26	Benzoxazolinone derivatives, preparation and pharmaceutical compositons
EP0172233A4 (en)	1986-07-29	PUNAGLANDINS AND THEIR PHARMACEUTICAL USE.
ZA879706B (en)	1988-06-21	New alkanesulfonanilide derivatives,processes for preparation thereof and pharmaceutical composition comprising the same
GB8909798D0 (en)	1989-06-14	Ws1128 substances,preparation thereof and pharmaceutical composition comprising the same
GB8905818D0 (en)	1989-04-26	New furylthiazole derivatives,processes for the preparation thereof and pharmaceutical composition comprising the same
GB8920977D0 (en)	1989-11-01	New pyridylthiazole derivatives,processes for the preparation thereof and pharmaceutical composition comprising the same
GB8928610D0 (en)	1990-02-21	New thiazolthiazole derivatives,processes for the preparation thereof and pharmaceutical composition comprising the same

Legal Events

Date	Code	Title	Description
2004-12-15	PC	Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)