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GR73621B - - Google Patents

Info

Publication number
GR73621B
GR73621B GR63629A GR800163629A GR73621B GR 73621 B GR73621 B GR 73621B GR 63629 A GR63629 A GR 63629A GR 800163629 A GR800163629 A GR 800163629A GR 73621 B GR73621 B GR 73621B
Authority
GR
Greece
Prior art keywords
amino acids
amino group
epsilon
lysine residue
optionally
Prior art date
Application number
GR63629A
Other languages
English (en)
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of GR73621B publication Critical patent/GR73621B/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/16—Somatostatin; related peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
GR63629A 1979-12-14 1980-12-12 GR73621B (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1109679 1979-12-14

Publications (1)

Publication Number Publication Date
GR73621B true GR73621B (el) 1984-03-26

Family

ID=4370005

Family Applications (1)

Application Number Title Priority Date Filing Date
GR63629A GR73621B (el) 1979-12-14 1980-12-12

Country Status (18)

Country Link
US (1) US4369179A (el)
EP (1) EP0030920B1 (el)
JP (1) JPS5692850A (el)
KR (2) KR850000415B1 (el)
AT (1) ATE6251T1 (el)
AU (1) AU544256B2 (el)
CA (1) CA1161033A (el)
DD (1) DD154098A5 (el)
DE (1) DE3066654D1 (el)
DK (1) DK532180A (el)
ES (1) ES8200861A1 (el)
FI (1) FI803849L (el)
GR (1) GR73621B (el)
IL (1) IL61696A0 (el)
NO (1) NO803757L (el)
NZ (1) NZ195817A (el)
PT (1) PT72191B (el)
ZA (1) ZA807796B (el)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3264693D1 (en) * 1981-12-24 1985-08-14 Ciba Geigy Ag Cyclic octapeptides and pharmaceutical compositions thereof, and processes for their production and use
FR2522655B1 (fr) * 1982-03-05 1987-03-06 Sanofi Sa Analogues de la somatostatine possedant une liaison du type hydrazide et medicaments en contenant
DE3379657D1 (en) * 1982-12-06 1989-05-24 Merck & Co Inc Dicyclic hexapeptides, processes for their preparation and pharmaceutical compositions containing them
US4485101A (en) * 1983-10-11 1984-11-27 Administrators Of The Tulane Educational Fund Peptides
US4612302A (en) * 1983-11-14 1986-09-16 Brigham And Women's Hospital Clinical use of somatostatin analogues
US4650787A (en) * 1985-04-25 1987-03-17 Schally Andrew Victor Biologically active octapeptides
US5633263A (en) * 1989-04-26 1997-05-27 The Administrators Of The Tulane Educational Fund Linear somatostatin analogs
JP2882679B2 (ja) * 1989-04-26 1999-04-12 ジ・アドミニストレーターズ・オブ・ザ・ツーレイン・エデュケイショナル・ファンド 線状ソマトスタチン類似体
US5504069A (en) * 1993-02-11 1996-04-02 Biomeasure, Inc. Inhibition of trauma-induced tumor growth
US5597894A (en) * 1995-06-05 1997-01-28 The Louisiana State University Medical Center Foundation Multi-tyrosinated somatostatin analogs
US5905140A (en) * 1996-07-11 1999-05-18 Novo Nordisk A/S, Novo Alle Selective acylation method
US6355613B1 (en) * 1996-07-31 2002-03-12 Peptor Limited Conformationally constrained backbone cyclized somatostatin analogs
US6004928A (en) * 1997-05-13 1999-12-21 Biomeasure, Incorporated Method of treating hyperlipidemia
EP0981364B1 (en) * 1997-05-13 2006-03-01 Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. Method and compositions for treating hyperlipidemia
US7034003B1 (en) 1997-05-13 2006-04-25 Societe De Conseils De Recherches Et D'applications Scientifiques, Sas Somatostatin and somatostatin agonists for decreasing body weight
PT980253E (pt) * 1997-05-13 2004-08-31 Conseils De Rec Appl Scient S Somatostatina e agonistas de somatostatina para tratar a insensibilidade a insulina e a sindrome x
US5968903A (en) * 1998-05-07 1999-10-19 Biomeasure, Incorporated Inhibition of H. pylori proliferation
AU2001279526A1 (en) * 2000-08-02 2002-02-13 Theratechnologies Inc. Modified peptides with increased potency
BR0210915A (pt) 2001-06-08 2004-06-08 Sod Conseils Rech Applic Análogos quiméricos de somatostatina-dopamina
US8709998B2 (en) 2003-04-22 2014-04-29 Ipsen Pharma S.A.S. Peptide vectors
AU2009259033B2 (en) 2008-06-12 2013-11-07 Ipsen Bioinnovation Limited Suppression of neuroendocrine diseases
JP5799397B2 (ja) 2008-06-12 2015-10-28 イプセン・バイオイノベーション・リミテッドＩｐｓｅｎ Ｂｉｏｉｎｎｏｖａｔｉｏｎ Ｌｉｍｉｔｅｄ 癌の抑制
GB0820970D0 (en) 2008-11-17 2008-12-24 Syntaxin Ltd Suppression of cancer
JP6869720B2 (ja) 2013-06-13 2021-05-12 アンチセンス セラピューティクス リミテッド 併用療法

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3875207A (en) * 1967-01-25 1975-04-01 Ciba Geigy Corp Process for the temporary protection of amino groups in peptide syntheses
US3944590A (en) * 1967-01-25 1976-03-16 Ciba-Geigy Corporation Process for the temporary protection of amino groups in peptide syntheses
US3725380A (en) * 1969-04-05 1973-04-03 Hoechst Ag Method of synthesizing peptides in the presence of a carbodiimide and a 1-hydroxy-benzotriazole
CH517705A (de) * 1969-12-16 1972-01-15 Ciba Geigy Ag Verfahren zur Herstellung von Cystin-haltigen Peptiden
DE2202613C3 (de) * 1972-01-20 1974-06-20 Farbwerke Hoechst Ag, Vormals Meister Lucius & Bruening, 6000 Frankfurt Verfahren zur Herstellung von Peptiden
CH577464A5 (el) * 1972-09-22 1976-07-15 Ciba Geigy Ag
US3882098A (en) * 1974-01-03 1975-05-06 American Home Prod Synthesis of des-Ala{hu 1{b , Gly{hu 2{b , Asn{hu 5{b -SRIF and intermediates
US4113714A (en) * 1975-01-03 1978-09-12 American Home Products Corporation [Des-Ala1, Gly2 -desamino-Cys3 ]somatostatin
US4130554A (en) * 1975-04-08 1978-12-19 Merck & Co., Inc. Process for preparing somatostatin analog
US4000259A (en) * 1975-06-16 1976-12-28 American Home Products Corporation Cyclic dodecapeptide analogs of somatostatin and intermediates
US3988304A (en) * 1975-08-25 1976-10-26 American Home Products Corporation Cyclic dodecapeptide derivatives of somatostatin and intermediates thereof
CA1083143A (en) * 1976-01-02 1980-08-05 Nedumparambil A. Abraham Carba derivatives of somatostatin and process therefor
US4062816A (en) * 1976-03-11 1977-12-13 Eli Lilly And Company D-Ala5 -somatostatin and intermediates thereto
US4098782A (en) * 1977-03-14 1978-07-04 American Home Products Corporation (His5)-somatostatin and analogues thereof
US4118380A (en) * 1977-07-25 1978-10-03 Ayerst, Mckenna & Harrison Limited Decapeptide analogs of somatostatin
US4115554A (en) * 1977-08-29 1978-09-19 Merck & Co., Inc. Somatostatin analogs
LU78191A1 (de) * 1977-09-28 1979-05-25 Ciba Geigy Ag Verfahren zur herstellung von neuen cyclopeptiden
US4140767A (en) * 1977-12-01 1979-02-20 Merck & Co., Inc. Somatostatin analogs
US4202802A (en) * 1978-10-02 1980-05-13 Eli Lilly And Company Peptides related to somatostatin
US4191754A (en) * 1979-02-28 1980-03-04 Merck & Co., Inc. Bicyclic somatostatin analogs
US4235886A (en) * 1979-10-31 1980-11-25 Merck & Co., Inc. Cyclic hexapeptide somatostatin analogs

Also Published As

Publication number Publication date
ZA807796B (en) 1982-01-27
EP0030920A3 (en) 1981-11-04
EP0030920A2 (de) 1981-06-24
PT72191A (de) 1981-01-01
EP0030920B1 (de) 1984-02-15
DD154098A5 (de) 1982-02-24
DE3066654D1 (en) 1984-03-22
KR830004216A (ko) 1983-07-06
NZ195817A (en) 1984-07-06
ES497696A0 (es) 1981-11-16
KR850000415B1 (ko) 1985-03-26
DK532180A (da) 1981-06-15
PT72191B (de) 1982-01-13
FI803849L (fi) 1981-06-15
AU544256B2 (en) 1985-05-23
KR850000414B1 (ko) 1985-03-26
ES8200861A1 (es) 1981-11-16
AU6534580A (en) 1981-06-18
CA1161033A (en) 1984-01-24
JPS5692850A (en) 1981-07-27
ATE6251T1 (de) 1984-03-15
US4369179A (en) 1983-01-18
IL61696A0 (en) 1981-01-30
NO803757L (no) 1981-06-15

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