Nothing Special   »   [go: up one dir, main page]

FR2422956A1 - Procede de detection et de caracterisation d'un acide nucleique ou d'une sequence de celui-ci, et reactif enzymatique pour la mise en oeuvre de ce procede - Google Patents

Procede de detection et de caracterisation d'un acide nucleique ou d'une sequence de celui-ci, et reactif enzymatique pour la mise en oeuvre de ce procede

Info

Publication number
FR2422956A1
FR2422956A1 FR7810975A FR7810975A FR2422956A1 FR 2422956 A1 FR2422956 A1 FR 2422956A1 FR 7810975 A FR7810975 A FR 7810975A FR 7810975 A FR7810975 A FR 7810975A FR 2422956 A1 FR2422956 A1 FR 2422956A1
Authority
FR
France
Prior art keywords
nucleic acid
characterization
implementation
sequence
detection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7810975A
Other languages
English (en)
Other versions
FR2422956B1 (fr
Inventor
Philippe Kourilsky
Stratis Avrameas
Brigitte Cami
Jean-Luc Guesdon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut Pasteur de Lille
Original Assignee
Institut Pasteur de Lille
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9207099&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FR2422956(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Institut Pasteur de Lille filed Critical Institut Pasteur de Lille
Priority to FR7810975A priority Critical patent/FR2422956A1/fr
Priority to DE2915082A priority patent/DE2915082C3/de
Priority to NL7902911A priority patent/NL191541C/xx
Priority to GB7913031A priority patent/GB2019408B/en
Priority to CH3527/79A priority patent/CH647870A5/fr
Priority to BE0/194623A priority patent/BE875598A/fr
Priority to JP4444379A priority patent/JPS54143297A/ja
Priority to IT21838/79A priority patent/IT1119725B/it
Publication of FR2422956A1 publication Critical patent/FR2422956A1/fr
Publication of FR2422956B1 publication Critical patent/FR2422956B1/fr
Application granted granted Critical
Priority to US06/373,017 priority patent/US4581333A/en
Priority to US07/940,750 priority patent/US5955262A/en
Priority to US08/466,275 priority patent/US5876928A/en
Priority to US08/471,462 priority patent/US5605800A/en
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/81Packaged device or kit
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/975Kit

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Procédé de détection de la présence éventuelle d'un fragment d'ADN, notamment d'un gène, au sein d'un échantillon d'acides nucléiques complexe. Il comprend l'hybridation du fragment recherché avec une sonde ARN, celle-ci étant, antérieurement ou postérieurement à l'hybridation, marquée avec une enzyme. Application à la recherche de gènes ou fragments d'ADN particuliers au sein d'un écjantillon biologique.
FR7810975A 1978-04-13 1978-04-13 Procede de detection et de caracterisation d'un acide nucleique ou d'une sequence de celui-ci, et reactif enzymatique pour la mise en oeuvre de ce procede Granted FR2422956A1 (fr)

Priority Applications (12)

Application Number Priority Date Filing Date Title
FR7810975A FR2422956A1 (fr) 1978-04-13 1978-04-13 Procede de detection et de caracterisation d'un acide nucleique ou d'une sequence de celui-ci, et reactif enzymatique pour la mise en oeuvre de ce procede
DE2915082A DE2915082C3 (de) 1978-04-13 1979-04-12 Verfahren und Verwendung eines Reagenzsatzes zum Nachweis und zur Charakterisierung von Nukleinsäuren und ihren Sequenzen
NL7902911A NL191541C (nl) 1978-04-13 1979-04-12 Werkwijze voor het aantonen van een nucleïnezuursequentie en een kit en een koppelingsprodukt daarvoor.
GB7913031A GB2019408B (en) 1978-04-13 1979-04-12 Method of detecting and characterizing a nucleic acid or a sequence of the latter and enzymatic reactant for the application of this method
JP4444379A JPS54143297A (en) 1978-04-13 1979-04-13 Method of detecting and identifying nucleic acid or arrangement thereof* and enzyme reacting substance for said method
BE0/194623A BE875598A (fr) 1978-04-13 1979-04-13 Procede de detection et de caracterisation d'un acide nucleique ou d'une sequence de celui-ci, et reactif enzymatique utilise
CH3527/79A CH647870A5 (fr) 1978-04-13 1979-04-13 Procede d'analyse d'une sequence ou fragment determine d'acide nucleique et moyens de mise en oeuvre du procede.
IT21838/79A IT1119725B (it) 1978-04-13 1979-04-13 Processo di rivelazione e di caratterizzazione di un acido nucleico o di una sua sequenza e reattivo enzimatico per la realizzazione di questo processo
US06/373,017 US4581333A (en) 1978-04-13 1982-04-29 Method of detecting and characterizing a nucleic acid or reactant for the application of this method
US07/940,750 US5955262A (en) 1978-04-13 1992-09-08 Method of detecting and characterizing a nucleic acid or reactant for the application of this method
US08/466,275 US5876928A (en) 1978-04-13 1995-06-06 Method of detecting and characterizing a nucleic acid or a sequence of the latter, and enzymatic reactant for the application of this method
US08/471,462 US5605800A (en) 1978-04-13 1995-06-06 Method of detecting and characterizing a nucleic acid or a sequence of the latter, and enzymatic reactant for the application of this method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7810975A FR2422956A1 (fr) 1978-04-13 1978-04-13 Procede de detection et de caracterisation d'un acide nucleique ou d'une sequence de celui-ci, et reactif enzymatique pour la mise en oeuvre de ce procede

Publications (2)

Publication Number Publication Date
FR2422956A1 true FR2422956A1 (fr) 1979-11-09
FR2422956B1 FR2422956B1 (fr) 1980-11-28

Family

ID=9207099

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7810975A Granted FR2422956A1 (fr) 1978-04-13 1978-04-13 Procede de detection et de caracterisation d'un acide nucleique ou d'une sequence de celui-ci, et reactif enzymatique pour la mise en oeuvre de ce procede

Country Status (9)

Country Link
US (3) US4581333A (fr)
JP (1) JPS54143297A (fr)
BE (1) BE875598A (fr)
CH (1) CH647870A5 (fr)
DE (1) DE2915082C3 (fr)
FR (1) FR2422956A1 (fr)
GB (1) GB2019408B (fr)
IT (1) IT1119725B (fr)
NL (1) NL191541C (fr)

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2578847A1 (fr) * 1985-03-13 1986-09-19 Centre Nat Rech Scient Sonde adn destinee au diagnostic antenatal de certaines anomalies chromosomiques
US7052887B2 (en) 2000-01-13 2006-05-30 Bio-Rad Pasteur Method for immobilization of (an) affinity reagent(s) on a hydrophobic solid phase
US7148015B2 (en) 1997-12-05 2006-12-12 Wyeth Circovirus sequences associated with piglet weight loss disease (PWD)
US7223407B2 (en) 1997-12-05 2007-05-29 Wyeth Circovirus sequences associated with piglet weight loss disease (PWD)
EP1925672A1 (fr) 2001-06-22 2008-05-28 Syngeta Participations AG Polynucléotides et polypeptides sensibles au stress abiotique
EP1950221A2 (fr) 1997-08-14 2008-07-30 Institut Pasteur Séquences génomiques de polypeptides exportés de mycobactéries, vecteurs les comprenant et applications au diagnostic et à la prévention de la tuberculose
EP2058325A2 (fr) 1998-04-16 2009-05-13 Institut Pasteur Procédé d'isolation d'un polynucléotides d'intérêt à partir du génome d'une mycobactérie utilisant une bibliothèque d'ADN de base BAC Application de la détection de mycobactéries
EP2218731A1 (fr) 1997-11-28 2010-08-18 Merck Serono Biodevelopment Séquence génomique de Chlamydia pneumoniae, polypeptides, fragments et leurs utilisations, en particulier pour le diagnostic, la prévention et le traitement de l'infection
US9388398B2 (en) 2005-11-02 2016-07-12 Battelle Energy Alliance, Llc Alteration and modulation of protein activity by varying post-translational modification
US9404134B2 (en) 2008-01-31 2016-08-02 Battelle Energy Alliance, Llc Thermophilic and thermoacidophilic biopolymer degrading genes and enzymes from Alicyclobacillus acidocaldarius and related organisms, methods
US9499824B2 (en) 2008-02-22 2016-11-22 Battelle Energy Alliance, Llc. Transcriptional control in alicyclobacillus acidocaldarius and associated genes, proteins, and methods
US9567595B2 (en) 2010-05-05 2017-02-14 Battelle Energy Alliance, Llc Type II restriction modification system methylation subunit of Alicyclobacillus acidocaldarius
EP3192880A1 (fr) 2010-08-18 2017-07-19 Fred Hutchinson Cancer Research Center Agents d'acides nucléiques pour le traitement de la dystrophie facioscapulohumérale (fshd)
US9987348B2 (en) 2013-09-25 2018-06-05 Zoetis Services Llc PCV2B divergent vaccine composition and methods of use
WO2018212770A1 (fr) 2017-05-17 2018-11-22 Thunder Biotech Inc. Macrophages transgéniques, récepteurs d'antigènes chimériques et méthodes associées
WO2019135879A1 (fr) 2018-01-05 2019-07-11 Thunder Biotech, Inc. Macrophages modifiés et précurseurs de macrophages et méthodes associées

Families Citing this family (270)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5605800A (en) * 1978-04-13 1997-02-25 Institut Pasteur Method of detecting and characterizing a nucleic acid or a sequence of the latter, and enzymatic reactant for the application of this method
FR2422956A1 (fr) * 1978-04-13 1979-11-09 Pasteur Institut Procede de detection et de caracterisation d'un acide nucleique ou d'une sequence de celui-ci, et reactif enzymatique pour la mise en oeuvre de ce procede
US6297355B1 (en) 1978-12-22 2001-10-02 Biogen, Inc. Polypeptides displaying HBV antigenicity or hbv antigen specificity
US6835557B1 (en) 1980-01-08 2004-12-28 Biogen, Inc. DNA sequences, recombinant DNA molecules and processes for producing human interferon-like polypeptides
US4530901A (en) * 1980-01-08 1985-07-23 Biogen N.V. Recombinant DNA molecules and their use in producing human interferon-like polypeptides
CA1341604C (fr) 1980-04-03 2010-05-04 Biogen N.V. Sequences d'adn, molecules d'adn recombine, ainsi que des procedes pour produire des polypeptides de fibroblastes humaine semblables a l'interferon
US4711955A (en) * 1981-04-17 1987-12-08 Yale University Modified nucleotides and methods of preparing and using same
ATE48140T1 (de) * 1981-04-17 1989-12-15 Univ Yale Modifizierte nukleotide und verfahren zu ihrer herstellung und anwendung.
CA1180647A (fr) * 1981-07-17 1985-01-08 Cavit Akin Methode de diagnostic d'hybridation de polynucleotides par emission de lumiere
JPS5840099A (ja) * 1981-07-17 1983-03-08 アモコ・コ−ポレ−ション 光−放射ポリヌクレオチドの交雑診断方法
EP0155359B1 (fr) * 1981-09-25 1988-01-07 John A. Webster, Jr. Méthode d'identification et de caractérisation d'organismes
US5614361A (en) * 1981-09-25 1997-03-25 Webster, Jr.; John A. Method for identifying and characterizing organisms
ATE39267T1 (de) * 1981-09-25 1988-12-15 John A Webster Jr Verfahren zur identifizierung und charakterisierung von organismen.
US4717653A (en) * 1981-09-25 1988-01-05 Webster John A Jr Method for identifying and characterizing organisms
FI63596C (fi) * 1981-10-16 1983-07-11 Orion Yhtymae Oy Mikrobdiagnostiskt foerfarande som grundar sig pao skiktshybridisering av nukleinsyror och vid foerfarandet anvaenda kombinationer av reagenser
FR2518755B1 (fr) * 1981-12-23 1986-04-11 Pasteur Institut Sonde contenant un acide nucleique modifie et reconnaissable par des anticorps specifiques et utilisation de cette sonde pour detecter et caracteriser une sequence d'adn homologue
JPS58502165A (ja) * 1981-12-23 1983-12-15 アンステイテユ・パストウ−ル 特異抗体により認識し得る修飾核酸プローブを使用して核酸配列の存在を検出する方法
US5260433A (en) * 1982-06-23 1993-11-09 Enzo Diagnostics, Inc. Saccharide specific binding system labeled nucleotides
US5241060A (en) * 1982-06-23 1993-08-31 Enzo Diagnostics, Inc. Base moiety-labeled detectable nucleatide
US7220854B1 (en) 1982-06-23 2007-05-22 Enzo Life Sciences, Inc. C/O Enzo Biochem, Inc. Sugar moiety labeled nucleotide, and an oligo- or polynucleotide, and other compositions comprising such sugar moiety labeled nucleotides
CA1223831A (fr) 1982-06-23 1987-07-07 Dean Engelhardt Nucleotides modifies, methodes de preparation et d'utilisation et composes les contenant
US4556643A (en) * 1982-07-26 1985-12-03 Agracetus Assay method and probe for polynucleotide sequences
US6818393B1 (en) 1982-07-30 2004-11-16 Biomirieux Sa DNA sequences coding for the DR beta-chain locus of the human lymphocyte antigen complex and polypeptides, diagnostic typing processes and products related thereto
EP0103960B1 (fr) * 1982-07-30 1991-01-23 Mach, Bernard François, Prof. Séquences d'ADN codant pour le locus DR de la chaîne bêta du complexe de l'antigène de lymphocytes humains et polypeptides, procédés diagnostiques de caractérisation et produits y relatifs
US4689295A (en) * 1983-01-20 1987-08-25 Integrated Genetics, Inc. Test for Salmonella
US4994373A (en) * 1983-01-27 1991-02-19 Enzo Biochem, Inc. Method and structures employing chemically-labelled polynucleotide probes
GB8306426D0 (en) * 1983-03-09 1983-04-13 Malcolm A D B Detecting polynucleotide sequence
DE3310337A1 (de) * 1983-03-22 1984-09-27 Europäisches Laboratorium für Molekularbiologie (EMBL), 6900 Heidelberg Verfahren zur durchfuehrung von hybridisierungsreaktionen
GB8311905D0 (en) * 1983-04-29 1983-06-02 Cox R A Isolation and detection of nucleotide sequence
CA1228811A (fr) 1983-05-05 1987-11-03 Robert G. Pergolizzi Methode d'analyse utilisant des sequences de polynucleotides
CA1220818A (fr) * 1983-05-05 1987-04-21 Hugh A.O. Hill Methodes d'essais biologiques utilisant des agents de liaison specifiques
DE3485811T2 (de) * 1983-05-31 1993-01-07 Orgenics Ltd Molekulare genetische sonde und verfahren zu ihrer herstellung, testmethode und satz in denen diese molekulare genetische sonde gebraucht wird.
US5221609A (en) * 1983-05-31 1993-06-22 Orgenics Ltd. Molecular genetic probe, and method of forming same, assay technique and kit using said molecular genetic probe
US4987065A (en) * 1983-07-05 1991-01-22 Enzo Biochem, Inc. In vivo labelling of polynucleotide sequences
CA1222705A (fr) * 1983-07-14 1987-06-09 Molecular Diagnostics, Inc. Methode photochimique rapide de marquage des acides nucleiques pour les deceler dans les epreuves d'hybridation
US4959309A (en) * 1983-07-14 1990-09-25 Molecular Diagnostics, Inc. Fast photochemical method of labelling nucleic acids for detection purposes in hybridization assays
US4737454A (en) * 1983-07-14 1988-04-12 Molecular Diagnostics, Inc. Fast photochemical method of labelling nucleic acids for detection purposes in hybridization assays
US5200313A (en) * 1983-08-05 1993-04-06 Miles Inc. Nucleic acid hybridization assay employing detectable anti-hybrid antibodies
US4626501A (en) * 1983-09-02 1986-12-02 Integrated Genetics, Inc. Labeled DNA
NO843838L (no) * 1983-09-26 1985-03-27 Ortho Diagnostic Systems Inc Fremgangsmaate for detektering av nukleinsyre
FR2552879B1 (fr) * 1983-10-03 1987-08-14 Pasteur Institut Procede et reactifs pour la detection d'une anomalie genetique dans une matiere biologique, notamment dans une preparation de leucocytes
US4743535A (en) * 1984-11-07 1988-05-10 Miles Inc. Hybridization assay employing labeled probe and anti-hybrid
WO1985002627A1 (fr) * 1983-12-16 1985-06-20 Genetics International, Inc. Analyse d'acides nucleiques
US4943523A (en) * 1984-01-30 1990-07-24 Enzo Biochem, Inc. Detectable molecules, method of preparation and use
US4843122A (en) * 1984-01-30 1989-06-27 Enzo Biochem, Inc. Detectable molecules, method of preparation and use
US4849208A (en) * 1984-01-30 1989-07-18 Enzo Biochem, Inc. Detectable molecules, method of preparation and use
US4707440A (en) * 1984-01-30 1987-11-17 Enzo Biochem, Inc. Nucleic acid hybridization assay and detectable molecules useful in such assay
US4849505A (en) * 1984-01-30 1989-07-18 Enzo Biochem, Inc. Detectable molecules, method of preparation and use
US5002885A (en) * 1984-01-30 1991-03-26 Enzo Biochem, Inc. Detectable molecules, method preparation and use
AU3844485A (en) * 1984-02-09 1985-08-15 Enzo Biochem Inc. Heterologous detection of cabeled dna
US4748111A (en) * 1984-03-12 1988-05-31 Molecular Diagnostics, Inc. Nucleic acid-protein conjugate used in immunoassay
US4582789A (en) * 1984-03-21 1986-04-15 Cetus Corporation Process for labeling nucleic acids using psoralen derivatives
US4617261A (en) * 1984-03-21 1986-10-14 Cetus Corporation Process for labeling nucleic acids and hybridization probes
US4840892A (en) * 1984-05-15 1989-06-20 Smithkline Beckman Corporation Polynucleotide hybridization probes
US4670380A (en) * 1984-05-23 1987-06-02 Molecular Diagnostics, Inc. Assays utilizing labeled nucleic acid probes
DE3431536A1 (de) * 1984-08-28 1986-03-13 Boehringer Mannheim Gmbh, 6800 Mannheim Derivatisierte nucleinsaeure-sequenz, verfahren zu deren herstellung sowie deren verwendung zum nachweis von nucleinsaeuren
US4563417A (en) * 1984-08-31 1986-01-07 Miles Laboratories, Inc. Nucleic acid hybridization assay employing antibodies to intercalation complexes
US4820630A (en) * 1984-11-23 1989-04-11 Digene Diagnostics, Incorporated Assay for nucleic acid sequences, particularly genetic lesions, using interactive labels
US4692509A (en) * 1984-11-27 1987-09-08 Molecular Diagnostics, Inc. Radioactive labeling of proteins with nucleosides or nucleotides
DE3587845T2 (de) * 1984-12-03 1994-10-20 Hoechst Celanese Corp Verfahren zur Bestimmung eines Liganden.
US4670379A (en) * 1984-12-19 1987-06-02 E. I. Du Pont De Nemours And Company Polynucleotide hydridization assays employing catalyzed luminescence
US6197563B1 (en) 1985-03-28 2001-03-06 Roche Molecular Systems, Inc. Kits for amplifying and detecting nucleic acid sequences
US6040166A (en) 1985-03-28 2000-03-21 Roche Molecular Systems, Inc. Kits for amplifying and detecting nucleic acid sequences, including a probe
GB8509880D0 (en) * 1985-04-17 1985-05-22 Ici Plc Testing device
US5273882A (en) * 1985-06-13 1993-12-28 Amgen Method and kit for performing nucleic acid hybridization assays
ES8707343A1 (es) * 1985-06-13 1987-07-16 Amgen Un metodo para aislar una secuencia de acido nucleico objetivo seleccionada
US4806546A (en) * 1985-09-30 1989-02-21 Miles Inc. Immobilization of nucleic acids on derivatized nylon supports
US4806631A (en) * 1985-09-30 1989-02-21 Miles Inc. Immobilization of nucleic acids on solvolyzed nylon supports
US4789630A (en) * 1985-10-04 1988-12-06 Cetus Corporation Ionic compounds containing the cationic meriquinone of a benzidine
NZ218050A (en) * 1985-11-13 1989-05-29 Wistar Inst Test for the presence of htlv-1v
JPS63502477A (ja) * 1985-12-03 1988-09-22 エル・ギユ−リイ・エム・ラフアツト 病気診断のための方法、装置および製品
US4882269A (en) * 1985-12-13 1989-11-21 Princeton University Amplified hybridization assay
US4822731A (en) * 1986-01-09 1989-04-18 Cetus Corporation Process for labeling single-stranded nucleic acids and hybridizaiton probes
US5447841A (en) 1986-01-16 1995-09-05 The Regents Of The Univ. Of California Methods for chromosome-specific staining
US5756696A (en) * 1986-01-16 1998-05-26 Regents Of The University Of California Compositions for chromosome-specific staining
US7115709B1 (en) * 1986-01-16 2006-10-03 The Regents Of The University Of California Methods of staining target chromosomal DNA employing high complexity nucleic acid probes
US6280929B1 (en) 1986-01-16 2001-08-28 The Regents Of The University Of California Method of detecting genetic translocations identified with chromosomal abnormalities
US6475720B1 (en) 1986-01-16 2002-11-05 The Regents Of The University Of California Chromosome-specific staining to detect genetic rearrangements associated with chromosome 3 and/or chromosome 17
US6872817B1 (en) 1986-01-16 2005-03-29 The Regents Of The Univ. Of California Method of staining target interphase chromosomal DNA
US5721098A (en) * 1986-01-16 1998-02-24 The Regents Of The University Of California Comparative genomic hybridization
US4935357A (en) * 1986-02-05 1990-06-19 New England Biolabs, Inc. Universal restriction endonuclease
US5418133A (en) * 1986-08-12 1995-05-23 The Australian National University Sex determination in cattle, sheep and goats using y-chromosome polynucleotides
US5714380A (en) 1986-10-23 1998-02-03 Amoco Corporation Closed vessel for isolating target molecules and for performing amplification
US5660983A (en) * 1986-12-04 1997-08-26 Mycogen Plant Science, Inc. Maize cytoplasmic male sterility type T (cms-T) mitochondria DNA
AU619170B2 (en) * 1987-01-09 1992-01-23 Abbott Laboratories Diagnostic assays using nucleic acid probes
AU622104B2 (en) * 1987-03-11 1992-04-02 Sangtec Molecular Diagnostics Ab Method of assaying of nucleic acids, a reagent combination and kit therefore
EP0304934A3 (fr) * 1987-08-26 1989-07-26 Hunger, Hans-Dieter Sondes moléculaires marquées, leur procédé de préparation et leur utilisation
US5384241A (en) * 1987-09-11 1995-01-24 Enzo Diagnostics, Inc. Specific binding assay compound with inhibitive self-quenching characteristics
PT88562B (pt) * 1987-09-21 1994-02-28 Ml Technology Ventures Metodo de ensaio de proteccao homogeneo para a deteccao de um analito
US6004745A (en) * 1987-09-21 1999-12-21 Gen-Probe Incorporated Hybridization protection assay
US5639604A (en) * 1987-09-21 1997-06-17 Gen-Probe Incorporated Homogeneous protection assay
DE3732145A1 (de) * 1987-09-24 1989-04-06 Merck Patent Gmbh Verfahren und reagenz zur durchfuehrung von hybridisierungsreaktionen
DE3742706A1 (de) * 1987-12-16 1989-06-29 Erich Prof Dr Med Liebhardt Verfahren zum identifizieren unbekannten biologischen materials
US5354657A (en) * 1988-01-12 1994-10-11 Boehringer Mannheim Gmbh Process for the highly specific detection of nucleic acids in solid
FR2680374B1 (fr) * 1988-03-25 1993-11-12 Bioprobe Systems Sa Procede de coloration d'acides nucleiques detectes par marquage non radioactif et ensemble de reactifs pour la mise en óoeuvre de ce procede.
US6326136B1 (en) * 1988-04-01 2001-12-04 Digene Corporation Macromolecular conjugate made using unsaturated aldehydes
US5109124A (en) * 1988-06-01 1992-04-28 Biogen, Inc. Nucleic acid probe linked to a label having a terminal cysteine
US5858652A (en) * 1988-08-30 1999-01-12 Abbott Laboratories Detection and amplification of target nucleic acid sequences
US6203977B1 (en) * 1988-11-15 2001-03-20 Yale University Delineation of individual human chromosomes in metaphase and interphase cells by in situ suppression hybridization
US5489507A (en) * 1988-11-30 1996-02-06 Perkin-Elmer Corporation DNA detection by color complementation
US5237016A (en) * 1989-01-05 1993-08-17 Siska Diagnostics, Inc. End-attachment of oligonucleotides to polyacrylamide solid supports for capture and detection of nucleic acids
DE69028725T2 (de) * 1989-02-28 1997-03-13 Canon Kk Partiell doppelsträngiges Oligonukleotid und Verfahren zu seiner Bildung
EP0462224B1 (fr) * 1989-03-10 1994-08-31 Millipore Corporation Mise en sequence d'acides nucleiques utilisant la detection chimioluminescente
DE4001154A1 (de) * 1990-01-17 1991-07-18 Boehringer Mannheim Gmbh Verfahren zur herstellung von modifizierten nukleinsaeuren
CA2031659A1 (fr) * 1990-01-26 1991-07-27 John B. Findlay Reactif hydrosoluble; sonde d'acide nucleique; trousse d'essai et diagnostic; methodes de purification
NL9001639A (nl) * 1990-07-19 1992-02-17 Amc Amsterdam Pt-houdende verbinding, werkwijze voor de bereiding ervan, alsmede toepassing van dergelijke verbindingen.
US5714327A (en) * 1990-07-19 1998-02-03 Kreatech Diagnostics Platinum-containing compounds, methods for their preparation and applications thereof
JPH0499500A (ja) * 1990-08-17 1992-03-31 Kikkoman Corp アビジンまたはアビジン標識体の定量法およびビオチンまたはビオチン標識体の定量法
WO1992008808A1 (fr) * 1990-11-14 1992-05-29 Siska Diagnostics, Inc. Detection non isotopique d'acides nucleiques utilisant une technique d'hybridation en sandwich base sur des supports en polystyrene et compositions prevues a cet effet
JPH06504912A (ja) * 1991-01-14 1994-06-09 ニューヨーク・ユニバーシティ サイトカイン誘導蛋白質tsg−6、該tsg−6蛋白質をコードするdnaおよび該tsg−6蛋白質の利用
WO1992012176A1 (fr) * 1991-01-14 1992-07-23 New York University Proteine tsg-14 induite par la cytokine, adn codant cette proteine et ses utilisations
US5552279A (en) * 1991-03-22 1996-09-03 Amoco Corporation Nucleic acid probes for the detection of mycoplasma pneumoniae and mycoplasma genitalium
US5843667A (en) * 1991-03-22 1998-12-01 Amoco Corporation Nucleic acid probes for the detection for genital mycoplasmas
EP0648281A4 (fr) * 1991-09-10 1997-06-04 Jack D Love Amplification de cibles et de signaux d'adn/arn.
WO1993013114A1 (fr) * 1991-12-24 1993-07-08 Isis Pharmaceuticals, Inc. COMPOSITIONS ET PROCEDES DE MODULATION DE LA β-AMYLOIDE
JP3645903B2 (ja) 1992-03-04 2005-05-11 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 比較ゲノムハイブリダイゼーション(cgh)
US5976790A (en) 1992-03-04 1999-11-02 The Regents Of The University Of California Comparative Genomic Hybridization (CGH)
US7534567B2 (en) 1992-03-04 2009-05-19 The Regents Of The University Of California Detection of nucleic acid sequence differences by comparative genomic hybridization
WO1993020234A1 (fr) * 1992-03-31 1993-10-14 E.I. Du Pont De Nemours And Company Dosage rapide, a haute capacite, fonde sur l'acide nucleique
WO1995004832A1 (fr) * 1992-06-18 1995-02-16 Fuso Pharmaceutical Industries, Ltd. Procede de detection d'un acide nucleique
WO1994014067A1 (fr) * 1992-12-14 1994-06-23 T Cell Sciences, Inc. Diagnostic et traitement de la sarcoïdose
US5830645A (en) 1994-12-09 1998-11-03 The Regents Of The University Of California Comparative fluorescence hybridization to nucleic acid arrays
EP0807689B1 (fr) * 1994-12-29 2003-08-13 Eiken Kagaku Kabushiki Kaisha Procede de detection cellulaire
US5753787A (en) * 1995-04-10 1998-05-19 Yale University Nucleic acids encoding ancylostoma secreted protein
US5731148A (en) * 1995-06-07 1998-03-24 Gen-Probe Incorporated Adduct protection assay
US6277592B1 (en) 1996-07-31 2001-08-21 Purina Mills, Inc. Porcine leptin protein, nucleic acid sequences coding therefor and uses thereof
US6297027B1 (en) 1996-07-31 2001-10-02 Purina Mills, Inc. Bovine leptin protein, nucleic acid sequences coding therefor and uses thereof
US20020137904A1 (en) * 1998-03-27 2002-09-26 Patricia A. Billing-Medel Reagents and methods useful for detecting diseases of the gastrointestinal tract
JP3981416B2 (ja) * 1997-04-10 2007-09-26 ユニバーシティ メディカル センター ナイメーヘン Pca3タンパク質、pca3遺伝子、及びこれらの用途
US20050208567A1 (en) * 1997-04-25 2005-09-22 Billing-Medel Patricia A Reagents and methods useful for detecting diseases of the prostate
ES2271994T3 (es) 1997-05-02 2007-04-16 Gen-Probe Incorporated Hibridacion en dos pasos y captura de un polinucleotido.
IL124275A (en) * 1997-05-02 2002-03-10 Bio Merieux Vitek Inc A method to produce sequences of nucleic acids
US6534273B2 (en) 1997-05-02 2003-03-18 Gen-Probe Incorporated Two-step hybridization and capture of a polynucleotide
US6558901B1 (en) * 1997-05-02 2003-05-06 Biomerieux Vitek Nucleic acid assays
GB9722131D0 (en) 1997-10-20 1997-12-17 Medical Res Council Method
CA2315037A1 (fr) 1997-12-19 1999-07-01 Beth Israel Deaconess Medical Center Procedes et compositions servant a inhiber la croissance de cellules tumorales
US6322976B1 (en) 1998-05-28 2001-11-27 Medical Research Council Compositions and methods of disease diagnosis and therapy
WO2000079009A2 (fr) 1999-06-22 2000-12-28 Invitrogen Corporation Amorces et procedes ameliores destines a la detection et a la discrimination d'acides nucleiques
US6830902B1 (en) 1999-07-02 2004-12-14 Invitrogen Corporation Compositions and methods for enhanced sensitivity and specificity of nucleic acid synthesis
DE60043789D1 (de) 1999-07-09 2010-03-18 Gen Probe Inc HIV-1 Detektion mittels Nukleinsäureamplifizierung
EP1222266B1 (fr) * 1999-09-29 2006-03-29 Diagnocure Inc. L'arnm du pca3 dans les tissus benins et malins de la prostate
GB9928787D0 (en) 1999-12-03 2000-02-02 Medical Res Council Direct screening method
US6543535B2 (en) 2000-03-15 2003-04-08 Exxonmobil Upstream Research Company Process for stimulating microbial activity in a hydrocarbon-bearing, subterranean formation
US20030165859A1 (en) 2001-10-23 2003-09-04 Invitrogen Corporation Primers and methods for the detection and discrimination of nucleic acids
US6942972B2 (en) 2001-10-24 2005-09-13 Beckman Coulter, Inc. Efficient synthesis of protein-oligonucleotide conjugates
US6956484B2 (en) * 2001-12-21 2005-10-18 Reconnaissance International Substance testing devices with photo identification
US20030175828A1 (en) * 2002-03-15 2003-09-18 Lazar James G. Signal amplification by Hybrid Capture
US7199107B2 (en) * 2002-05-23 2007-04-03 Isis Pharmaceuticals, Inc. Antisense modulation of kinesin-like 1 expression
EP2292801B1 (fr) 2002-06-14 2018-08-08 Gen-Probe Incorporated Compositions et procédé pour la détection du virus de l'hépatite b
US7115374B2 (en) 2002-10-16 2006-10-03 Gen-Probe Incorporated Compositions and methods for detecting West Nile virus
WO2004070056A2 (fr) 2003-02-07 2004-08-19 Diagnocure Inc. Procede de detection de cancer de la prostate dans un echantillon
EP2251442B9 (fr) 2003-12-19 2012-04-25 Gen-Probe Incorporated Compositions, méthodes et kits destinés à la détection des acides nucléiques du VIH-1 et du VIH-2
WO2005079474A2 (fr) 2004-02-17 2005-09-01 The Regents Of The University Of California Detection de differences de sequences d'acide nucleique par hybridation genomique comparative
WO2005100538A1 (fr) 2004-04-16 2005-10-27 Spartan Bioscience Inc. Systeme pour l'amplification rapide et la detection d'acides nucleiques
CA2565980A1 (fr) 2004-05-12 2005-12-01 Luca Technologies, Llc Production d'hydrogene a partir de matieres comportant des hydrocarbures
ES2392445T3 (es) 2004-07-13 2012-12-10 Gen-Probe Incorporated Composiciones y métodos para la detección de ácido nucleico del virus de la hepatitis A
DK2975139T3 (da) 2004-09-30 2019-12-09 Gen Probe Inc Assay til at detektere og kvantificere hiv-1
WO2006137939A2 (fr) * 2004-11-09 2006-12-28 Gen-Probe Incorporated Compositions et methode de detection de streptocoques du groupe a
US20060275792A1 (en) * 2004-11-15 2006-12-07 Lee Jun E Enhancement of nucleic acid amplification using double-stranded DNA binding proteins
US20060105348A1 (en) * 2004-11-15 2006-05-18 Lee Jun E Compositions and methods for the detection and discrimination of nucleic acids
US7472576B1 (en) 2004-11-17 2009-01-06 State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Portland State University Nanometrology device standards for scanning probe microscopes and processes for their fabrication and use
CA2491067A1 (fr) 2004-12-24 2006-06-24 Stichting Katholieke Universiteit Rapport entre arnm dans les sediments urinaires ou l'urine en tant que marqueur pronostique du cancer de la prostate
DE602006018586D1 (de) * 2005-02-07 2011-01-13 Gen Probe Inc Zusammensetzungen und verfahren zum nachweis von streptokokken der gruppe b
US20060223159A1 (en) * 2005-04-05 2006-10-05 Luca Technologies, Llc Generation of materials with enhanced hydrogen content from microbial consortia including thermotoga
US20060223153A1 (en) * 2005-04-05 2006-10-05 Luca Technologies, Llc Generation of materials with enhanced hydrogen content from anaerobic microbial consortia
US20060223160A1 (en) * 2005-04-05 2006-10-05 Luca Technologies, Llc Systems and methods for the isolation and identification of microorganisms from hydrocarbon deposits
US7426960B2 (en) * 2005-05-03 2008-09-23 Luca Technologies, Inc. Biogenic fuel gas generation in geologic hydrocarbon deposits
CA2605015C (fr) 2005-05-06 2013-09-10 Gen-Probe Incorporated Compositions et analyses permettant de detecter des acides nucleiques des virus a et b de la grippe
ES2381279T3 (es) 2005-05-06 2012-05-24 Gen-Probe Incorporated Métodos y productos para la captura de ácido nucleico diana
EP1937847A2 (fr) 2005-10-17 2008-07-02 Gen-Probe Incorporated Compositions et procédés destinés à détecter des acides nucléiques de legionella pneumophila
US7416879B2 (en) * 2006-01-11 2008-08-26 Luca Technologies, Inc. Thermacetogenium phaeum consortium for the production of materials with enhanced hydrogen content
US20100248322A1 (en) * 2006-04-05 2010-09-30 Luca Technologies, Inc. Chemical amendments for the stimulation of biogenic gas generation in deposits of carbonaceous material
US7977282B2 (en) * 2006-04-05 2011-07-12 Luca Technologies, Inc. Chemical amendments for the stimulation of biogenic gas generation in deposits of carbonaceous material
US7696132B2 (en) 2006-04-05 2010-04-13 Luca Technologies, Inc. Chemical amendments for the stimulation of biogenic gas generation in deposits of carbonaceous material
WO2007134208A2 (fr) * 2006-05-12 2007-11-22 Gen-Probe Incorporated Compositions et procédés servant à détecter l'acide nucléique d'entérocoques
US9051601B2 (en) 2006-08-01 2015-06-09 Gen-Probe Incorporated Methods of nonspecific target capture of nucleic acids
US8198027B2 (en) 2006-12-21 2012-06-12 Gen-Probe Incorporated Methods and compositions for nucleic acid amplification
EP1978111B1 (fr) 2007-04-02 2013-03-27 Gen-Probe Incorporated Compositions, kits et procédés associés pour la détection et/ou la surveillance de Pseudomonas aeruginosa
EP2175999B1 (fr) 2007-06-21 2017-01-04 Gen-Probe Incorporated Réceptacles pour l'exécution de procédés
WO2009085704A2 (fr) 2007-12-26 2009-07-09 Gen-Probe Incorporated Compositions et procédés permettant de détecter l'acide nucléique du candida albicans
US8492114B2 (en) * 2008-01-25 2013-07-23 Battelle Energy Alliance, Llc Methods of combined bioprocessing and related microorganisms, thermophilic and/or acidophilic enzymes, and nucleic acids encoding said enzymes
US9732330B2 (en) 2008-01-25 2017-08-15 Battelle Energy Alliance, Llc Methods of combined bioprocessing and related microorganisms, thermophilic and/or acidophilic enzymes, and nucleic acids encoding said enzymes
CN101896602A (zh) * 2008-01-25 2010-11-24 巴特勒能源同盟有限公司 耐热和耐酸的β-木糖苷酶、编码基因、相关生物和方法
US8426185B2 (en) 2008-01-31 2013-04-23 Battelle Energy Alliance, Llc Thermophilic and thermoacidophilic biopolymer-degrading genes and enzymes from Alicyclobacillus acidocaldarius and related organisms, methods
JP2011510657A (ja) * 2008-01-31 2011-04-07 バテル エナジー アライアンス,エルエルシー アリサイクロバチルス・アシドカルダリウスおよび関連生物体に由来する好熱性および好熱好酸性バイオポリマー分解遺伝子および酵素、方法
US8557557B2 (en) * 2008-01-31 2013-10-15 Battelle Energy Alliance, Llc Thermophilic and thermoacidophilic biopolymer-degrading genes and enzymes from Alicyclobacillus acidocaldarius and related organisms, methods
EP2257566A4 (fr) 2008-02-26 2012-05-30 Battelle Energy Alliance Llc Gènes et enzymes transporteurs de glucides thermophiles et thermoacidophiles d alicyclobacillus acidocaldarius et organismes et procédés associés
AU2009310370A1 (en) * 2008-02-27 2010-05-06 Battelle Energy Alliance, Llc Thermophilic and thermoacidophilic glycosylation genes and enzymes from Alicyclobacillus acidocaldarius and related organisms, methods
CA2715526A1 (fr) 2008-02-28 2009-12-03 Battelle Energy Alliance, Llc Genes et enzymes a metabolisme thermophile et thermoacidophile d'alicyclobacillus acidocaldarius et d'organismes associes et procedes
WO2009131683A2 (fr) 2008-04-21 2009-10-29 Gen-Probe Incorporated Méthode de détection du virus du chikungunya
JP5733796B2 (ja) 2008-05-13 2015-06-10 ジェン−プロウブ インコーポレイテッド 標的核酸配列の選択的ハイブリダイゼーションおよび捕捉における使用のため不活化可能型標的捕捉オリゴマー
AU2009262870B2 (en) 2008-05-30 2014-03-20 Gen-Probe Incorporated Compositions, kits and related methods for the detection and/or monitoring of Salmonella
US8097412B2 (en) * 2008-07-12 2012-01-17 Biodiagnostics, Inc. DNA-based test for detection of annual and intermediate ryegrass
CA2638458A1 (fr) * 2008-07-31 2010-01-31 Spartan Bioscience Inc. Recyclage thermique au moyen du positionnement d'une source de temperature allant de relative a fixe
US20100035309A1 (en) * 2008-08-06 2010-02-11 Luca Technologies, Inc. Analysis and enhancement of metabolic pathways for methanogenesis
WO2010078374A1 (fr) 2008-12-30 2010-07-08 Gen-Probe Incorporated Composition, kits et méthodes correspondantes pour la détection et/ou la surveillance de listeria
CA2750900C (fr) 2009-01-30 2017-03-28 Gen-Probe Incorporated Systemes et procedes de detection d'un signal et d'application d'energie thermique a un element de transmission de signal
AU2010217928B2 (en) 2009-02-26 2013-06-06 Gen-Probe Incorporated Assay for detection of human parvovirus nucleic acid
US20100248321A1 (en) * 2009-03-27 2010-09-30 Luca Technologies, Inc. Surfactant amendments for the stimulation of biogenic gas generation in deposits of carbonaceous materials
WO2011003020A1 (fr) 2009-07-01 2011-01-06 Gen-Probe Incorporated Procédés et compositions pour l'amplification d'acide nucléique
US8479813B2 (en) * 2009-12-16 2013-07-09 Luca Technologies, Inc. Biogenic fuel gas generation in geologic hydrocarbon deposits
EP3040425B1 (fr) 2010-02-17 2019-08-28 Gen-Probe Incorporated Compositions et procédés pour détecter un acide nucléique de vaginae atopobium
EP3037555B1 (fr) 2010-04-21 2019-07-24 Gen-Probe Incorporated Compositions, procédés et trousses pour la détection d'acides nucléiques du virus de l'herpès simplex
US9822397B2 (en) 2010-06-30 2017-11-21 Gen-Probe Incorporated Method and apparatus for identifying analyte-containing samples using single-read determination of analyte and process control signals
EP3674423A1 (fr) 2010-07-12 2020-07-01 Gen-Probe Incorporated Compositions et tests permettant de détecter l'acide nucléique du virus de la grippe a saisonnière h3
WO2012030856A2 (fr) 2010-08-30 2012-03-08 Gen-Probe Incorporated Compositions, procédés et mélanges réactionnels pour détection du virus xénotrope apparenté aux virus de la leucémie murine
CA2811333C (fr) 2010-09-16 2020-05-12 Gen-Probe Incorporated Sondes de capture immobilisables par l'intermediaire d'une queue nucleotidique l
EP2625297B1 (fr) 2010-10-04 2018-10-10 Gen-Probe Prodesse, Inc. Compositions, méthodes et kits pour détecter des acides nucléiques adénoviraux
US9512467B2 (en) 2011-03-10 2016-12-06 Gen-Probe Incorporated Methods and compositions for the selection and optimization of oligonucleotide tag sequences
US9657352B2 (en) 2011-04-25 2017-05-23 Gen-Probe Incorporated Compositions and methods for detecting BV-associated bacterial nucleic acid
CA2841531C (fr) 2011-07-15 2021-11-09 Gen-Probe Incorporated Compositions et procedes de detection de l'acide nucleique du parvovirus humain et de detection des acides nucleiques du virus de l'hepatite a dans des dosages monoplexes ou multiplexes
EP2753713B1 (fr) 2011-09-08 2017-07-19 Gen-Probe Incorporated Compositions et procédés de détection d'acide nucléique bactérien associé à la vaginose bactérienne
EP2758547B1 (fr) 2011-09-21 2015-09-16 Gen-Probe Incorporated Procédés d'amplification d'acide nucléique à l'aide d'un déplacement à médiation par étiquette
DE102011120550B4 (de) 2011-12-05 2013-11-07 Gen-Probe Prodesse, Inc. Zusammensetzungen, Verfahren und Kits zur Detektion von Adenovirusnukleinsäuren
US11098375B2 (en) 2012-02-24 2021-08-24 Gen-Probe Prodesse, Inc. Detection of Shiga toxin genes in bacteria
US9004162B2 (en) 2012-03-23 2015-04-14 Transworld Technologies Inc. Methods of stimulating acetoclastic methanogenesis in subterranean deposits of carbonaceous material
AU2013205110B2 (en) 2012-04-24 2016-10-13 Gen-Probe Incorporated Compositions, Methods and Kits to Detect Herpes Simplex Virus Nucleic Acids
AU2013205064B2 (en) 2012-06-04 2015-07-30 Gen-Probe Incorporated Compositions and Methods for Amplifying and Characterizing HCV Nucleic Acid
EP2890814B1 (fr) 2012-08-30 2019-11-13 Gen-Probe Incorporated Amplification d'acides nucléiques en mode multiphase
AU2013205122B2 (en) 2012-10-11 2016-11-10 Gen-Probe Incorporated Compositions and Methods for Detecting Human Papillomavirus Nucleic Acid
AU2013205090B2 (en) 2012-12-07 2016-07-28 Gen-Probe Incorporated Compositions and Methods for Detecting Gastrointestinal Pathogen Nucleic Acid
US20160024565A1 (en) * 2013-03-13 2016-01-28 Tufts University Fragment complementation of based assays
CA2920672C (fr) 2013-08-14 2022-12-13 Gen-Probe Incorporated Compositions et procedes de detection de l'acide nucleique du hev
GB2555995B (en) 2014-10-20 2019-06-26 Gen Probe Inc Red blood cell lysis solution
JP6944873B2 (ja) 2015-01-09 2021-10-06 ジェン−プローブ・インコーポレーテッド 細菌性膣症を診断するための方法および組成物
US10550438B2 (en) 2015-03-16 2020-02-04 Gen-Probe Incorporated Methods and compositions for detecting bacterial nucleic acid
CN108350407B (zh) 2015-12-11 2022-07-08 杰诺玛迪克斯公司 用于核酸扩增的管密封系统和方法
JP6894439B2 (ja) 2016-01-04 2021-06-30 ジェン−プローブ・インコーポレーテッド Candida種を検出するための方法及び組成物
US20190284604A1 (en) 2016-02-05 2019-09-19 Gen-Probe Incorporated Dried amplification compositions
WO2017189746A1 (fr) 2016-04-27 2017-11-02 Gen-Probe Incorporated Réactif de lyse de cellules sanguines
JP6803930B2 (ja) 2016-06-10 2021-01-06 ジェン−プローブ・インコーポレーテッド Zikaウイルス核酸を検出するための組成物および方法
AU2017346854B2 (en) 2016-10-19 2024-05-23 Gen-Probe Incorporated Compositions and methods for detecting or quantifying hepatitis C virus
EP3541959A1 (fr) 2016-11-21 2019-09-25 Gen-Probe Incorporated Compositions et méthodes pour détecter ou quantifier le virus de l'hépatite b
US10844425B2 (en) 2017-03-24 2020-11-24 Gen-Probe Incorporated Compositions and methods for detecting or quantifying parainfluenza virus
EP4212635A1 (fr) 2017-03-24 2023-07-19 Gen-Probe Incorporated Compositions et procédés de détection de rsv a dans des échantillons
EP3601618B1 (fr) 2017-03-25 2024-09-04 Gen-Probe Incorporated Compositions, procédés et kits pour détecter des acides nucléiques d'adénovirus, de métapneumovirus et/ou de rhinovirus
CA3064603A1 (fr) 2017-06-07 2018-12-13 Gen-Probe Incorporated Detection d'acide nucleique d'espece babesia dans un echantillon
EP4282533A3 (fr) 2017-07-10 2024-03-13 Gen-Probe Incorporated Systèmes analytiques et procédés d'amplification d'acide nucléique à l'aide de paramètres d'attribution d'échantillon
WO2019032809A1 (fr) 2017-08-11 2019-02-14 Gen-Probe Incorporated Compositions et méthodes de détection de staphylococcus aureus
KR20200057720A (ko) * 2017-09-29 2020-05-26 베링거잉겔하임베트메디카게엠베하 샘플을 테스트하기 위한 센서 장치 및 방법
CN111465707A (zh) 2017-11-17 2020-07-28 简·探针公司 用于检测C1orf43核酸的组合物和方法
WO2019118735A1 (fr) 2017-12-15 2019-06-20 Gen-Probe Incorporated Compositions et méthodes pour la détection de clostridium difficile toxigène
US20210071242A1 (en) 2018-01-29 2021-03-11 Gen-Probe Incorporated Analytical systems and methods
GB2590210B (en) 2018-06-13 2023-01-25 Gen Probe Inc Compositions and methods for detecting group B Streptococcus nucleic acid
US20210317515A1 (en) 2018-07-10 2021-10-14 Gen-Probe Incorporated Methods and systems for detecting and quantifying nucleic acids
AU2019314449A1 (en) 2018-08-01 2021-03-11 Gen-Probe Incorporated Compositions and methods for detecting nucleic acids of Epstein-Barr virus
EP3841223A1 (fr) 2018-08-08 2021-06-30 Gen-Probe Incorporated Compositions, procédés et kits pour la détection de mycoplasma genitalium
CA3107043A1 (fr) 2018-08-21 2020-02-27 Gen-Probe Incorporated Compositions et procedes d'amplification, de detection ou de quantification de cytomegalovirus humain
CA3108906A1 (fr) 2018-08-24 2020-02-27 Gen-Probe Incorporated Compositions et procedes pour detecter un acide nucleique bacterien et diagnostiquer une vaginose bacterienne
EP3856934A2 (fr) 2018-09-27 2021-08-04 Gen-Probe Incorporated Compositions et procédés de détection d'acides nucléiques de bordetella pertussis et de bordetella parapertussis
JP7432610B2 (ja) 2018-10-01 2024-02-16 ジェン-プローブ・インコーポレーテッド 水痘帯状疱疹ウイルスを増幅または検出するための組成物および方法
JP7542546B2 (ja) 2018-10-22 2024-08-30 ジェン-プローブ・インコーポレーテッド ヒトポリオーマウイルスbkウイルスを増幅、検出または定量化するための組成物および方法
TW202030333A (zh) 2018-12-20 2020-08-16 美商簡 探針公司 用於檢測瘧原蟲物種核酸之組成物及方法
EP4400604A3 (fr) 2019-03-22 2024-10-16 Gen-Probe Incorporated Compositions et procédés de détection de streptocoques du groupe a
CA3176699A1 (fr) 2019-05-03 2020-11-12 Gen-Probe Incorporated Systeme de transport de receptacle pour systeme analytique
CN114286867B (zh) 2019-08-20 2024-04-16 青岛华大智造科技有限责任公司 一种基于发光标记物光信号动力学及二次发光信号对多核苷酸进行测序的方法
WO2021041056A1 (fr) 2019-08-23 2021-03-04 Gen-Probe Incorporated Compositions, procédés et kits pour la détection de treponema pallidum
AU2020343334A1 (en) 2019-09-05 2022-04-07 Gen-Probe Incorporated Detection of Chlamydia trachomatis nucleic acid variants
EP4114985A1 (fr) 2020-03-04 2023-01-11 Gen-Probe Incorporated Compositions et procédés pour détecter l'acide nucléique de sars-cov-2
US20230220499A1 (en) 2020-05-07 2023-07-13 Grifols Diagnostic Solutions Inc. Methods and compositions for detecting sars-cov-2 nucleic acid
CN116323440A (zh) 2020-10-21 2023-06-23 简·探针公司 流体容器管理系统
EP4377481A1 (fr) 2021-07-27 2024-06-05 Gen-Probe Incorporated Compositions et procédés de détection d'agents pathogènes gastro-intestinaux
WO2023175434A1 (fr) 2022-03-15 2023-09-21 Diagenode S.A. Détection de l'état de méthylation d'un échantillon d'adn
WO2024054924A1 (fr) 2022-09-08 2024-03-14 Gen-Probe Incorporated Procédé de détection d'analytes d'acides nucléiques à l'aide d'amorces à double spécificité
WO2024137379A2 (fr) 2022-12-19 2024-06-27 Gen-Probe Incorporated Compositions et procédés de détection d'agents pathogènes gastro-intestinaux
WO2024161179A1 (fr) 2023-01-31 2024-08-08 Mobidiag Oy Compositions et procédés de détection d'acides nucléiques stx
WO2024192338A1 (fr) 2023-03-16 2024-09-19 Gen-Probe Incorporated Compositions et procédés de détection de parasites gastro-intestinaux
EP4455303A1 (fr) 2023-04-28 2024-10-30 Mobidiag Oy Commandes de processus d'amplification d'acide nucléique
EP4455304A1 (fr) 2023-04-28 2024-10-30 Mobidiag Oy Commandes de processus d'amplification d'acide nucléique
EP4454758A1 (fr) 2023-04-28 2024-10-30 Mobidiag Oy Commandes de processus d'amplification d'acide nucléique

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3654090A (en) * 1968-09-24 1972-04-04 Organon Method for the determination of antigens and antibodies
NL154598B (nl) * 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
NL154599B (nl) * 1970-12-28 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen, alsmede testverpakking.
US4067774A (en) * 1971-05-14 1978-01-10 Syva Company Compounds for enzyme amplification assay
US3817837A (en) * 1971-05-14 1974-06-18 Syva Corp Enzyme amplification assay
US3880934A (en) * 1972-02-10 1975-04-29 Syntex Inc Nitrophenyloxy-butanediols
NL171930C (nl) * 1972-05-11 1983-06-01 Akzo Nv Werkwijze voor het aantonen en bepalen van haptenen, alsmede testverpakkingen.
US4002532A (en) * 1974-10-21 1977-01-11 Weltman Joel K Enzyme conjugates
IN142734B (fr) * 1975-04-28 1977-08-20 Miles Lab
US4016043A (en) * 1975-09-04 1977-04-05 Akzona Incorporated Enzymatic immunological method for the determination of antigens and antibodies
US4134792A (en) * 1976-12-06 1979-01-16 Miles Laboratories, Inc. Specific binding assay with an enzyme modulator as a labeling substance
US4139346A (en) * 1977-11-28 1979-02-13 Enzo Bio Chem Incorporated Nucleic acid and protein binding paper
US4318980A (en) * 1978-04-10 1982-03-09 Miles Laboratories, Inc. Heterogenous specific binding assay employing a cycling reactant as label
US5605800A (en) * 1978-04-13 1997-02-25 Institut Pasteur Method of detecting and characterizing a nucleic acid or a sequence of the latter, and enzymatic reactant for the application of this method
FR2422956A1 (fr) * 1978-04-13 1979-11-09 Pasteur Institut Procede de detection et de caracterisation d'un acide nucleique ou d'une sequence de celui-ci, et reactif enzymatique pour la mise en oeuvre de ce procede
US4228237A (en) * 1978-09-21 1980-10-14 Calbiochem-Behring Corp. Methods for the detection and determination of ligands
EP0041426B1 (fr) * 1980-05-22 1985-11-13 Institut Pasteur Produit de couplage entre une lectine et un ligand spécifique, obtention et application dans le domaine biologique
US4358535A (en) * 1980-12-08 1982-11-09 Board Of Regents Of The University Of Washington Specific DNA probes in diagnostic microbiology
US4442204A (en) * 1981-04-10 1984-04-10 Miles Laboratories, Inc. Homogeneous specific binding assay device and preformed complex method
DE3485811T2 (de) * 1983-05-31 1993-01-07 Orgenics Ltd Molekulare genetische sonde und verfahren zu ihrer herstellung, testmethode und satz in denen diese molekulare genetische sonde gebraucht wird.
EP0155854B1 (fr) * 1984-03-22 1990-09-26 Bresatec Limited Matériel de test biologique non-radioactif
DE3568063D1 (en) * 1985-01-10 1989-03-09 Molecular Diagnostics Inc Photochemical method of labelling nucleic acids for detection in hybridization assays
US4868105A (en) * 1985-12-11 1989-09-19 Chiron Corporation Solution phase nucleic acid sandwich assay

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CA1977 *

Cited By (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986005512A1 (fr) * 1985-03-13 1986-09-25 Centre National De La Recherche Scientifique (Cnrs Sonde adn destinee au diagnostic antenatal de certaines anomalies chromosomiques
FR2578847A1 (fr) * 1985-03-13 1986-09-19 Centre Nat Rech Scient Sonde adn destinee au diagnostic antenatal de certaines anomalies chromosomiques
EP1950221A2 (fr) 1997-08-14 2008-07-30 Institut Pasteur Séquences génomiques de polypeptides exportés de mycobactéries, vecteurs les comprenant et applications au diagnostic et à la prévention de la tuberculose
EP2228385A1 (fr) 1997-11-28 2010-09-15 Merck Serono Biodevelopment Séquence génomique de Chlamydia pneumoniae, polypeptides, fragments et leurs utilisations, en particulier pour le diagnostic, la prévention et le traitement de l'infection
EP2228384A1 (fr) 1997-11-28 2010-09-15 Merck Serono Biodevelopment Séquence génomique de Chlamydia pneumoniae, polypeptides, fragments et leurs utilisations, en particulier pour le diagnostic, la prévention et le traitement de l'infection
EP2218730A1 (fr) 1997-11-28 2010-08-18 Merck Serono Biodevelopment Séquence génomique de Chlamydia pneumoniae, polypeptides, fragments et leurs utilisations, en particulier pour le diagnostic, la prévention et le traitement de l'infection
EP2218732A1 (fr) 1997-11-28 2010-08-18 Merck Serono Biodevelopment Séquence génomique de Chlamydia pneumoniae, polypeptides, fragments et leurs utilisations, en particulier pour le diagnostic, la prévention et le traitement de l'infection
EP2218731A1 (fr) 1997-11-28 2010-08-18 Merck Serono Biodevelopment Séquence génomique de Chlamydia pneumoniae, polypeptides, fragments et leurs utilisations, en particulier pour le diagnostic, la prévention et le traitement de l'infection
EP2000535A1 (fr) 1997-12-05 2008-12-10 Wyeth a Corporation of the State of Delaware Séquences de circovirus associé à la maladie de l'amaigrissement du porcelet (MAP)
US7223407B2 (en) 1997-12-05 2007-05-29 Wyeth Circovirus sequences associated with piglet weight loss disease (PWD)
US7297537B2 (en) 1997-12-05 2007-11-20 Wyeth Circovirus sequences associated with piglet weight loss disease (PWD)
US7314628B2 (en) 1997-12-05 2008-01-01 Wyeth Circovirus sequences associated with piglet weight loss disease (PWD)
US7323330B2 (en) 1997-12-05 2008-01-29 Wyeth Circovirus sequences associated with piglet weight loss disease (PWD)
US10052375B2 (en) 1997-12-05 2018-08-21 Zoetics Services LLC Circovirus sequences associated with piglet weight loss disease (PWD)
US7390494B2 (en) 1997-12-05 2008-06-24 Wyeth Circovirus sequences associated with piglet weight loss disease (PWD)
US7405075B2 (en) 1997-12-05 2008-07-29 Wyeth Circovirus sequences associated with piglet weight loss disease (PWD)
US7258865B2 (en) 1997-12-05 2007-08-21 Wyeth Circovirus sequences associated with piglet weight loss disease (PWD)
US7407803B2 (en) 1997-12-05 2008-08-05 Wyeth Circovirus sequences associated with piglet weight loss disease (PWD)
US7425444B2 (en) 1997-12-05 2008-09-16 Wyeth Circovirus sequences associated with piglet weight loss disease (PWD)
EP1992696A1 (fr) 1997-12-05 2008-11-19 Wyeth a Corporation of the State of Delaware Séquences de circovirus associé à la maladie de l'amaigrissement du porcelet (MAP)
US7244433B2 (en) 1997-12-05 2007-07-17 Wyeth Circovirus sequences associated with piglet weight loss disease (PWD)
US9717784B2 (en) 1997-12-05 2017-08-01 Zoetis Services Llc Circovirus sequences associated with piglet weight loss disease (PWD)
US7604808B2 (en) 1997-12-05 2009-10-20 Wyeth Circovirus sequences associated with piglet weight loss disease (PWD)
US7722883B2 (en) 1997-12-05 2010-05-25 Wyeth Circovirus sequences associated with piglet weight loss disease (PWD)
US7740865B2 (en) 1997-12-05 2010-06-22 Wyeth Circovirus sequences associated with piglet weight loss disease (PWD)
US7261898B2 (en) 1997-12-05 2007-08-28 Wyeth Circovirus sequences associated with piglet weight loss disease (PWD)
US7223594B2 (en) 1997-12-05 2007-05-29 Wyeth Circovirus sequences associated with piglet weight loss disease (PWD)
US7179472B2 (en) 1997-12-05 2007-02-20 Wyeth Circovirus sequences associated with piglet weight loss disease (PWD)
US7148015B2 (en) 1997-12-05 2006-12-12 Wyeth Circovirus sequences associated with piglet weight loss disease (PWD)
US9700613B2 (en) 1997-12-05 2017-07-11 Zoetis Services Llc Circovirus sequences associated with piglet weight loss disease (PWD)
EP2316925A1 (fr) 1997-12-05 2011-05-04 Wyeth LLC Séquences de circovirus associé à la maladie de l'amaigrissement du porcelet (MAP)
EP2330188A1 (fr) 1997-12-05 2011-06-08 Wyeth LLC Séquences de circovirus associé à la maladie de l'amaigrissement du porcelet (MAP)
EP2058325A2 (fr) 1998-04-16 2009-05-13 Institut Pasteur Procédé d'isolation d'un polynucléotides d'intérêt à partir du génome d'une mycobactérie utilisant une bibliothèque d'ADN de base BAC Application de la détection de mycobactéries
US7052887B2 (en) 2000-01-13 2006-05-30 Bio-Rad Pasteur Method for immobilization of (an) affinity reagent(s) on a hydrophobic solid phase
EP1925672A1 (fr) 2001-06-22 2008-05-28 Syngeta Participations AG Polynucléotides et polypeptides sensibles au stress abiotique
US9388398B2 (en) 2005-11-02 2016-07-12 Battelle Energy Alliance, Llc Alteration and modulation of protein activity by varying post-translational modification
US9404134B2 (en) 2008-01-31 2016-08-02 Battelle Energy Alliance, Llc Thermophilic and thermoacidophilic biopolymer degrading genes and enzymes from Alicyclobacillus acidocaldarius and related organisms, methods
US9499824B2 (en) 2008-02-22 2016-11-22 Battelle Energy Alliance, Llc. Transcriptional control in alicyclobacillus acidocaldarius and associated genes, proteins, and methods
US9567595B2 (en) 2010-05-05 2017-02-14 Battelle Energy Alliance, Llc Type II restriction modification system methylation subunit of Alicyclobacillus acidocaldarius
EP3192880A1 (fr) 2010-08-18 2017-07-19 Fred Hutchinson Cancer Research Center Agents d'acides nucléiques pour le traitement de la dystrophie facioscapulohumérale (fshd)
US9987348B2 (en) 2013-09-25 2018-06-05 Zoetis Services Llc PCV2B divergent vaccine composition and methods of use
WO2018212770A1 (fr) 2017-05-17 2018-11-22 Thunder Biotech Inc. Macrophages transgéniques, récepteurs d'antigènes chimériques et méthodes associées
WO2019135879A1 (fr) 2018-01-05 2019-07-11 Thunder Biotech, Inc. Macrophages modifiés et précurseurs de macrophages et méthodes associées

Also Published As

Publication number Publication date
GB2019408A (en) 1979-10-31
JPS54143297A (en) 1979-11-08
DE2915082C2 (fr) 1989-07-13
NL191541C (nl) 1995-09-04
US5876928A (en) 1999-03-02
IT7921838A0 (it) 1979-04-13
GB2019408B (en) 1982-08-18
NL191541B (nl) 1995-05-01
DE2915082C3 (de) 1995-04-20
DE2915082A1 (de) 1979-10-31
US5955262A (en) 1999-09-21
NL7902911A (nl) 1979-10-16
CH647870A5 (fr) 1985-02-15
BE875598A (fr) 1979-10-15
IT1119725B (it) 1986-03-10
JPH0364119B2 (fr) 1991-10-03
US4581333A (en) 1986-04-08
FR2422956B1 (fr) 1980-11-28

Similar Documents

Publication Publication Date Title
FR2422956A1 (fr) Procede de detection et de caracterisation d'un acide nucleique ou d'une sequence de celui-ci, et reactif enzymatique pour la mise en oeuvre de ce procede
US8224582B2 (en) Non-equilibrium capillary electrophoresis of equilibrium mixtures (NECEEM)-based methods for drug and diagnostic development
GB2274710A (en) Gene probe biosensor method
DE69032410D1 (de) Vorrichtung zur behandlung biologischer proben für die analyse von nukleinsäuren
ATE342356T1 (de) Prostata-spezifisches membranantigen
ES529179A0 (es) Un metodo de detectar una secuencia de polinucleotido.
NO852022L (no) Nukleinsyre-hybridiseringsanalyse ved anvendelse av detekterbare anti-hybrid-antistoffer.
US5656429A (en) Polynucleotide and protein analysis method using magnetizable moieties
Egyházi et al. Microinjection of anti-topoisomerase I immunoglobulin G into nuclei of Chironomus tentans salivary gland cells leads to blockage of transcription elongation
ES2052607T3 (es) Metodos y kits para detectar secuencias de acidos nucleicos.
CN114269916A (zh) 用于样品分析的装置和方法
JPH0743376B2 (ja) 核酸配列の検定方法及び分子遺伝子プローブ
Chen et al. An ultrasensitive chemiluminescence strategy based on a microchip platform for telomerase detection at a single-cell level
Uryu et al. Research note: Determination of the sex of chickens by a biotin-labeled deoxyribonucleic acid probe
US5667654A (en) Real time in-gel assay
SE9500341D0 (sv) Method for detecting DNA sequence variations
US6743578B1 (en) Method for the detection of specific nucleic acid sequences by polymerase nucleotide incorporation
JPS62143700A (ja) 対合セグメント抑制または競合による核酸アツセイ法
RU2193069C2 (ru) Способ обнаружения мутаций дезоксирибонуклеиновых кислот с помощью рестриктаз и набор для проведения способа
JP3296078B2 (ja) 酵素免疫検査法
Chen et al. Study on gene sensor based on primer extension
JPH07265076A (ja) 免疫検査法
TEST et al. ONE-STEP CEPHALOSPORIN C AMIDASE ENZYME
IT1207905B (it) Frantumatore vaglio per trattamento a secco dei residui pressati di oleifici
IT1207913B (it) Riserva di sicurezza per formatori di gradienti usati nella cromatografia a scambio ionico su colonne