Nothing Special   »   [go: up one dir, main page]

FR2335229A1 - Nouveaux derives de quinazolone, leur preparation et leur utilisation en tant que medicaments - Google Patents

Nouveaux derives de quinazolone, leur preparation et leur utilisation en tant que medicaments

Info

Publication number
FR2335229A1
FR2335229A1 FR7638135A FR7638135A FR2335229A1 FR 2335229 A1 FR2335229 A1 FR 2335229A1 FR 7638135 A FR7638135 A FR 7638135A FR 7638135 A FR7638135 A FR 7638135A FR 2335229 A1 FR2335229 A1 FR 2335229A1
Authority
FR
France
Prior art keywords
preparation
new
medicinal products
quinazolone derivatives
quinazolone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7638135A
Other languages
English (en)
Other versions
FR2335229B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CH Boehringer Sohn AG and Co KG
Original Assignee
CH Boehringer Sohn AG and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CH Boehringer Sohn AG and Co KG filed Critical CH Boehringer Sohn AG and Co KG
Publication of FR2335229A1 publication Critical patent/FR2335229A1/fr
Application granted granted Critical
Publication of FR2335229B1 publication Critical patent/FR2335229B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FR7638135A 1975-12-19 1976-12-17 Nouveaux derives de quinazolone, leur preparation et leur utilisation en tant que medicaments Granted FR2335229A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2557425A DE2557425C2 (de) 1975-12-19 1975-12-19 11-Oxo-11-H-pyrido[2,1-b]-chinazolin-2-carbonsäure und ihre Salze, Verfahren zu ihrer Herstellung und Arzneimittel

Publications (2)

Publication Number Publication Date
FR2335229A1 true FR2335229A1 (fr) 1977-07-15
FR2335229B1 FR2335229B1 (fr) 1980-04-11

Family

ID=5964943

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7638135A Granted FR2335229A1 (fr) 1975-12-19 1976-12-17 Nouveaux derives de quinazolone, leur preparation et leur utilisation en tant que medicaments

Country Status (36)

Country Link
US (2) US4083980A (fr)
JP (1) JPS5831350B2 (fr)
AT (1) AT352736B (fr)
AU (1) AU513469B2 (fr)
BE (1) BE849542A (fr)
BG (3) BG25092A3 (fr)
CA (1) CA1199914A (fr)
CH (4) CH627754A5 (fr)
CS (1) CS198222B2 (fr)
DD (1) DD128812A5 (fr)
DE (1) DE2557425C2 (fr)
DK (1) DK149107C (fr)
ES (3) ES454405A1 (fr)
FI (1) FI64159C (fr)
FR (1) FR2335229A1 (fr)
GB (1) GB1572707A (fr)
GR (1) GR62109B (fr)
HK (1) HK12984A (fr)
HU (1) HU172929B (fr)
IE (1) IE45256B1 (fr)
IL (1) IL51124A (fr)
LU (1) LU76417A1 (fr)
MX (1) MX4488E (fr)
MY (1) MY8500078A (fr)
NL (1) NL182535C (fr)
NO (1) NO147450C (fr)
NZ (1) NZ182915A (fr)
PH (1) PH16310A (fr)
PL (5) PL102308B1 (fr)
PT (1) PT65981A (fr)
RO (3) RO75248A (fr)
SE (1) SE431456B (fr)
SG (1) SG55483G (fr)
SU (4) SU645571A3 (fr)
YU (2) YU39048B (fr)
ZA (1) ZA767490B (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2424924A1 (fr) * 1978-05-05 1979-11-30 Bristol Myers Co Nouvelles azolopyrimidinones, leur procede de production et medicament les contenant
EP0015065A1 (fr) * 1979-01-24 1980-09-03 Warner-Lambert Company Dérivés de la pyrazolo (5,1-b) quinazolin-9(4H)-one, procédé pour leur préparation et compositions pharmaceutiques les contenant

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4337255A (en) * 1977-07-29 1982-06-29 E. R. Squibb & Sons, Inc. Pyrazolo[1,5-c]quinazoline derivatives and related compounds
HU182009B (en) * 1977-08-19 1983-12-28 Chinoin Gyogyszer Es Vegyeszet Process for producing substituted pirido-square bracket-1,2-a-square bracket closed-pyrimidines, pyrrolo-square bracket-1,2-a-square bracket closed-pyrimidines
DE2739020A1 (de) 1977-08-26 1979-03-01 Schering Ag Pyrido eckige klammer auf 2,1-b eckige klammer zu -chinazolinon-derivate, ihre herstellung und verwendung
US4348396A (en) * 1978-01-23 1982-09-07 Hoffmann-La Roche Inc. Substituted 11-oxo-11H-pyrido[2,1-b]quinazolines and method of inhibiting allergic reactions with them
US4168380A (en) 1978-04-21 1979-09-18 Hoffmann-La Roche Inc. 7-Methoxy-5-oxo-5H-thiazolo[2,3-b]quinazoline-2-carboxylic acid
US4491587A (en) * 1978-05-05 1985-01-01 Mead Johnson & Company Tetrazole derivatives
US4209620A (en) * 1978-06-19 1980-06-24 Bristol-Myers Company Substituted 3-(1H-tetrazol-5-yl)-4H-pyrido[1,2-a]pyrimidin-4-one derivatives having antiallergy activity
DE2845766A1 (de) * 1978-10-18 1980-04-30 Schering Ag Pyrido eckige klammer auf 2,1-b eckige klammer zu -chinazolinon-derivate, ihre herstellung und verwendung
US4282360A (en) * 1979-10-12 1981-08-04 Hoffmann-La Roche Inc. 7-Methylthio or methylsulfinyl-5-oxo-5H-thiazolo[2,3-b]quinazoline-2-carboxylic acid
US4302585A (en) 1980-12-22 1981-11-24 American Home Products Corporation 3-Hydroxy-3-substituted phenylthiazolo[2,3-b]quinazoline-2-alkanoic acids and their lactones
US4395549A (en) 1981-10-02 1983-07-26 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt. 6-Hydrazono-pyrido[2,1-b] quinazoline-11 ones
DE3142728A1 (de) * 1981-10-28 1983-05-05 Basf Ag, 6700 Ludwigshafen Herbizide, enthaltend thiazolo(2,3-b)-chinazolone als wirkstoffe, und ihre verwendung zur beeinflussung des pflanzenwachstums
DE3142727A1 (de) * 1981-10-28 1983-05-05 Basf Ag, 6700 Ludwigshafen Thiazolo (2,3-b)-chinazolone, verfahren zu ihrer herstellung und ihre verwendung zur beeinflussung des pflanzenwachstums
ES8406476A1 (es) * 1982-04-29 1984-07-01 Erba Farmitalia Procedimiento para preparar derivados cicloalifaticos condensados de pirido(1,2-a)pirimidinas sustituidas.
US4551460A (en) * 1982-05-10 1985-11-05 Hoffmann-La Roche Inc. Pyrido[2,1-b]quinazoline derivatives useful as agents for treatment of allergic conditions and vascular disorders involving thrombosis
US4455312A (en) * 1982-08-19 1984-06-19 Portnyagina Vera A 2-(o-Carboxyphenylamino)-6H-pyrimido(2,1-b)-quinazolone-6 and derivatives thereof, and application as antiphlogistics
DE3300477A1 (de) * 1983-01-08 1984-07-12 Boehringer Ingelheim KG, 6507 Ingelheim Neue heterocyclische verbindungen, ihre herstellung und verwendung
GB8300728D0 (en) * 1983-01-12 1983-02-16 Erba Farmitalia Substituted carboxy-thiazolo / 3 2 - a / pyrimidine derivatives
EP0142057A3 (fr) * 1983-11-04 1988-03-30 F. Hoffmann-La Roche Ag Dérivés de thiazoloquinazoline, leur préparation et compositions pharmaceutiques les contenant
US4588812A (en) * 1984-05-30 1986-05-13 Pennwalt Corporation Substituted 2,3-dihydro-5H-thiazolo[2,3,-b]quinazoline derivatives
US4738964A (en) * 1984-05-30 1988-04-19 Pennwalt Corporation Method of suppressing the immune system comprising administering 5H-thiazolo[2,3-b]quinazoline-3(2H)-one
JPS61204475A (ja) * 1985-03-07 1986-09-10 松下電工株式会社 ２台収納立体ガレ−ジのパレツト落下防止装置
DE3634532A1 (de) * 1986-10-10 1988-04-14 Basf Ag Verfahren zur herstellung von thiazolo-(2,3-b)chinazolonen
DE3704203A1 (de) * 1987-02-11 1988-08-25 Boehringer Ingelheim Kg Verwendung von oxochinazolinderivaten bei der behandlung der hyperurikaemie
US4904667A (en) * 1989-02-24 1990-02-27 Ortho Pharmaceutical Corporation 1H-1,2,4-thiadiazolo(3,4-b)quinazolin-5-one-2,2-dioxides, and a method for increasing the cardiac output of a mammal with them
US6800651B2 (en) 2000-02-03 2004-10-05 Eli Lilly And Company Potentiators of glutamate receptors
US8946223B2 (en) 2010-04-12 2015-02-03 Millennium Pharmaceuticals, Inc. Substituted hydroxamic acids and uses thereof
WO2012054332A1 (fr) 2010-10-18 2012-04-26 Millennium Pharmaceuticals, Inc. Acides hydroxamiques substitués et leurs utilisations
TW201629026A (zh) 2015-02-02 2016-08-16 佛瑪治療公司 作為ｈｄａｃ抑制劑的３－烷基雙環［４，５，０］異羥肟酸
WO2016126726A1 (fr) 2015-02-02 2016-08-11 Forma Therapeutics, Inc. Acides hydroxamiques bicycliques [4,6,0] en tant qu'inhibiteurs hdac6
WO2017218950A1 (fr) 2016-06-17 2017-12-21 Forma Therapeutics, Inc. Indanes d'acide hydroxamique 2-spiro-5 et 6 utilisés en tant qu'inhibiteurs de hdac

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1242863A (en) * 1968-05-10 1971-08-18 Pharmacia As 2,3-DIHYDRO-5H-THIAZOLO[2,3-b]QUINAZOLINES AND PROCESSES FOR THE PREPARATION THEREOF
US3598823A (en) * 1969-05-28 1971-08-10 Sandoz Ag Tricyclic quinazolinones
CA984842A (en) 1972-02-28 1976-03-02 Charles M. Hall 1,4,6,9-tetrahydro-4,6-dioxopyrido-(3,2-g)-quinoline-2,8-dicarboxylic acid compounds
US3833588A (en) * 1972-04-25 1974-09-03 Sandoz Ag Unsaturated-substituted tricyclic quinazolinones
JPS5752352B2 (fr) * 1974-02-28 1982-11-06
US4012387A (en) * 1975-09-18 1977-03-15 Warner-Lambert Company Benzo-[g]pyrido[2,1-b]quinazolinones
US4033961A (en) * 1975-10-07 1977-07-05 Warner-Lambert Company Pyrido[2-1-b]quinazolin-ones and their methods of preparation
US4142049A (en) * 1976-10-18 1979-02-27 Warner-Lambert Company Benzo[g]pyrido[2,1-b]quinazolinones
US4066767A (en) * 1976-11-01 1978-01-03 Warner-Lambert Company 8-(1H-Tetrazol-5-yl)-11H-pyrido[2,1-b]quinazolin-11-ones and method of treating bronchial asthma using them
NZ186760A (en) * 1977-03-24 1981-03-16 Hoffmann La Roche 11hpyrido (2,1-b) quinazolin-11-ones and pharmaceutical compositions
DE2739020A1 (de) * 1977-08-26 1979-03-01 Schering Ag Pyrido eckige klammer auf 2,1-b eckige klammer zu -chinazolinon-derivate, ihre herstellung und verwendung
US4168380A (en) * 1978-04-21 1979-09-18 Hoffmann-La Roche Inc. 7-Methoxy-5-oxo-5H-thiazolo[2,3-b]quinazoline-2-carboxylic acid

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2424924A1 (fr) * 1978-05-05 1979-11-30 Bristol Myers Co Nouvelles azolopyrimidinones, leur procede de production et medicament les contenant
EP0015065A1 (fr) * 1979-01-24 1980-09-03 Warner-Lambert Company Dérivés de la pyrazolo (5,1-b) quinazolin-9(4H)-one, procédé pour leur préparation et compositions pharmaceutiques les contenant

Also Published As

Publication number Publication date
CS198222B2 (en) 1980-05-30
NO147450C (no) 1983-04-13
NO764303L (fr) 1977-06-21
RO75734A (fr) 1982-07-06
ES454405A1 (es) 1978-01-16
DK149107C (da) 1986-06-09
IL51124A0 (en) 1977-02-28
IE45256B1 (en) 1982-07-28
FR2335229B1 (fr) 1980-04-11
US4083980A (en) 1978-04-11
SU652894A3 (ru) 1979-03-15
US4332802A (en) 1982-06-01
PL101141B1 (pl) 1978-12-30
MY8500078A (en) 1985-12-31
LU76417A1 (fr) 1978-01-18
CH625522A5 (fr) 1981-09-30
IL51124A (en) 1980-06-30
ES464162A1 (es) 1978-09-01
FI64159B (fi) 1983-06-30
PH16310A (en) 1983-09-05
ES464136A1 (es) 1978-09-01
CA1199914A (fr) 1986-01-28
JPS5277096A (en) 1977-06-29
HK12984A (en) 1984-02-24
GB1572707A (en) 1980-07-30
YU39048B (en) 1984-02-29
AT352736B (de) 1979-10-10
SU784776A3 (ru) 1980-11-30
BG25092A3 (en) 1978-07-12
YU115282A (en) 1983-12-31
ATA883976A (de) 1979-03-15
PL111422B1 (en) 1980-08-30
CH627754A5 (de) 1982-01-29
NZ182915A (en) 1979-07-11
BG25093A3 (en) 1978-07-12
SU645571A3 (ru) 1979-01-30
SE431456B (sv) 1984-02-06
FI763469A (fr) 1977-06-20
AU2069576A (en) 1978-06-22
AU513469B2 (en) 1980-12-04
JPS5831350B2 (ja) 1983-07-05
FI64159C (fi) 1983-10-10
NL182535C (nl) 1988-04-05
SU733516A3 (ru) 1980-05-05
DK567376A (da) 1977-06-20
PL103556B1 (pl) 1979-06-30
YU40078B (en) 1985-06-30
BE849542A (fr) 1977-06-17
DK149107B (da) 1986-01-27
RO69411A (fr) 1982-02-01
CH625243A5 (fr) 1981-09-15
IE45256L (en) 1977-06-19
YU308276A (en) 1982-08-31
PL110780B1 (en) 1980-07-31
MX4488E (es) 1982-05-21
CH631983A5 (de) 1982-09-15
GR62109B (en) 1979-02-26
NL182535B (nl) 1987-11-02
SE7614258L (sv) 1977-06-20
NL7614013A (nl) 1977-06-21
NO147450B (no) 1983-01-03
HU172929B (hu) 1979-01-28
DD128812A5 (de) 1977-12-14
DE2557425C2 (de) 1987-03-19
ZA767490B (en) 1978-08-30
SG55483G (en) 1984-07-27
RO75248A (fr) 1980-11-30
PL102308B1 (pl) 1979-03-31
BG24673A3 (en) 1978-04-12
DE2557425A1 (de) 1977-06-30
PT65981A (pt) 1977-01-01

Similar Documents

Publication Publication Date Title
BE849542A (fr) Nouveaux derives de quinazolone, leur preparation et leur utilisation en tant en tant que medicaments
FR2329266A1 (fr) Nouveaux amino-benzamides, leur preparation et leur utilisation en tant que medicaments
FR2343731A1 (fr) Nouveaux aminoalcoylheterocycles, procedes pour leur preparation et leur utilisation en tant que medicaments
FR2305975A2 (fr) Nouvelles amidinourees, leurs procedes de preparation et leur application en tant que medicaments
FR2432511B1 (fr) Derives triazoliques, leur preparation et leur application en tant que medicaments
BE854843A (fr) Nouveaux derives d'acides phosphoneux, leur preparation et leur application en tant que medicaments
BE863160A (fr) Nouveaux derives aminoalcoxyphenyles, leur preparation et leur utilisation en tant que medicaments
MC1223A1 (fr) Nouveaux derives de 2-imino-imidazolidine,leur preparation et leur application en tant que medicaments
FR2303560A1 (fr) Nouveaux polypeptides, leur preparation et leur application comme medicaments
LU79949A1 (fr) Nouveaux derives solubles de 2,4-diamino-pyrimidines,leur preparation et leur utilisation en tant que medicaments
BE847861A (fr) Nouveaux amino-benzamides, leur preparation et leur utilisation en tant que medicaments
BE874683A (fr) Nouveaux derives bicyclo-octaniques leur preparation et leur utilisation comme medicaments
BE869640A (fr) Nouveaux acides 2-pyridyl- et 2-pyrimidyl-amino-benzoiques, leur preparation et leur utilisation en tant que medicaments
FR2327767A1 (fr) Nouveaux derives de cyclohexylphenyle, leur preparation et leur utilisation en tant que medicaments
FR2316949A1 (fr) Derives du benzo-cyclohepta-thiophene, leur preparation et leur application comme medicaments
BE862275A (fr) Nouveaux acides sulfamoylbenzoiques, leur preparatrion et leur application en tant que medicaments
FR2341584A1 (fr) Nouveaux derives de thienothiazine, leur procede de preparation et leur application en tant que medicaments
FR2316939A1 (fr) Derives de 2-benzopyranone et leur application comme medicaments
BE864290A (fr) Nouveaux aryl-hexafuranosides, leur preparation et leur application en tant que medicaments
MC1222A1 (fr) Nouvelles 2,4-diamino-5-benzylpyrimidines,leur preparation et leur application en tant que medicaments
FR2314707A1 (fr) Nouveaux tetraiodo-terephtalates d'hydroxyalcoyle, leur preparation et leur application en tant que medicaments
FR2341557A1 (fr) Nouveaux derives de la 2-phenyl-2-hydroxyethylamine, leur preparation et leur utilisation en tant que medicaments
BE867339A (fr) Nouveaux derives de la 5-phenyl-1h-3-benzazepine, leur preparation et leur utilisation comme medicaments
BE853328A (fr) Nouveaux composes oxothia, leur preparation et leur application en tant que medicaments
BE856157A (fr) Nouveaux n-benzylaminoacides soufred, leur preparation et leur utilisation en tant que medicaments

Legal Events

Date Code Title Description
ST Notification of lapse