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FR2432511B1 - Derives triazoliques, leur preparation et leur application en tant que medicaments - Google Patents

Derives triazoliques, leur preparation et leur application en tant que medicaments

Info

Publication number
FR2432511B1
FR2432511B1 FR7910459A FR7910459A FR2432511B1 FR 2432511 B1 FR2432511 B1 FR 2432511B1 FR 7910459 A FR7910459 A FR 7910459A FR 7910459 A FR7910459 A FR 7910459A FR 2432511 B1 FR2432511 B1 FR 2432511B1
Authority
FR
France
Prior art keywords
medicaments
preparation
application
triazolic derivatives
triazolic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7910459A
Other languages
English (en)
Other versions
FR2432511A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of FR2432511A1 publication Critical patent/FR2432511A1/fr
Application granted granted Critical
Publication of FR2432511B1 publication Critical patent/FR2432511B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/14—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/12—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FR7910459A 1978-04-26 1979-04-25 Derives triazoliques, leur preparation et leur application en tant que medicaments Expired FR2432511B1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1646878 1978-04-26
GB7847689 1978-12-08
GB7907422 1979-03-02

Publications (2)

Publication Number Publication Date
FR2432511A1 FR2432511A1 (fr) 1980-02-29
FR2432511B1 true FR2432511B1 (fr) 1986-04-25

Family

ID=27257387

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7910459A Expired FR2432511B1 (fr) 1978-04-26 1979-04-25 Derives triazoliques, leur preparation et leur application en tant que medicaments

Country Status (20)

Country Link
US (3) US4318913A (fr)
AR (1) AR228941A1 (fr)
AT (1) AT376212B (fr)
AU (1) AU531224B2 (fr)
CA (1) CA1143727A (fr)
CH (1) CH647767A5 (fr)
DE (2) DE2954639C2 (fr)
DK (1) DK173579A (fr)
ES (4) ES8102104A1 (fr)
FI (1) FI791360A (fr)
FR (1) FR2432511B1 (fr)
IL (1) IL57178A (fr)
IT (1) IT1162304B (fr)
LU (1) LU81192A1 (fr)
NL (1) NL7903313A (fr)
NO (1) NO791387L (fr)
NZ (1) NZ190299A (fr)
PH (1) PH19534A (fr)
SE (1) SE7903698L (fr)
YU (2) YU100379A (fr)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR228941A1 (es) * 1978-04-26 1983-05-13 Glaxo Group Ltd Procedimiento para preparar nuevos derivados de 3,5-diamino-1,2,4-triazol que son activos contra receptores histaminicos
DK89480A (da) * 1979-03-02 1980-09-03 Glaxo Group Ltd R fremgangsmaade til fremstilling af heterocycliske forbindelse
US4410523A (en) * 1979-10-22 1983-10-18 Glaxo Group Limited Heterocyclic derivatives
US4777179A (en) * 1979-10-23 1988-10-11 Glaxo Group Limited Heterocyclic derivatives, processes for the use thereof and pharmaceutical compositions containing them
FR2477150A1 (fr) * 1980-02-28 1981-09-04 Glaxo Group Ltd Nouveaux derives heterocycliques, procedes pour leur preparation et compositions pharmaceutiques les comportant
JPS5775976A (en) * 1980-08-27 1982-05-12 Glaxo Group Ltd Novel heterocyclic derivative, manufacture and medicinal composition containing same
FI82241C (fi) * 1980-12-30 1991-02-11 Glaxo Group Ltd Foerfarande foer framstaellning av n-/2-//5-/(dimetylamino)metyl/-2-furanylmetyl/tio/etyl/-n'-metyl -2-nitro-1,1-etendiamin.
DK558181A (da) * 1981-01-30 1982-07-31 Smithkline Corp Fremgangsmaade til fremstilling af 3,5-diamino-1,2,4-triazoler
US4522943A (en) * 1981-05-18 1985-06-11 Bristol-Myers Company Chemical compounds
US4526973A (en) * 1981-05-18 1985-07-02 Bristol-Myers Company Chemical compounds
IE53068B1 (en) * 1981-06-15 1988-05-25 Merck & Co Inc Diamino isothiazole-1-oxides and -1,1-dioxides as gastic secretion inhibitors
JPS5824572A (ja) * 1981-07-22 1983-02-14 グラクソ・グル−プ・リミテツド ヒスタミン受体に作用を有する化合物を含有する医薬組成物
CA1192545A (fr) * 1982-02-16 1985-08-27 Glaxo Group Limited Derives heterocycliques utilises comme antagonistes-h.sub.2 de l'histamine
KR840003621A (ko) * 1982-02-24 1984-09-15 원본미기재 헤테로 사이클릭 유도체의 제조방법
US4482552A (en) * 1982-02-26 1984-11-13 Glaxo Group Limited Triazole compounds and their pharmaceutical use
DE3366369D1 (en) * 1982-03-17 1986-10-30 Smith Kline French Lab Pyridine derivatives
US4520025A (en) * 1982-07-21 1985-05-28 William H. Rorer, Inc. Bicyclic nitrogen heterocyclic ethers and thioethers, and their pharmaceutical uses
US4543352A (en) * 1983-04-29 1985-09-24 William H. Rorer, Inc. Naphthalene aminoalkylene ethers and thioethers, and their pharmaceutical uses
US4529723A (en) * 1983-04-29 1985-07-16 William H. Rorer, Inc. Bicyclic benzenoid aminoalkylene ethers and thioethers, pharmaceutical compositions and use
US4481360A (en) * 1983-08-26 1984-11-06 The Upjohn Company 4H-1,2,4-Triazol-3-yl compounds
DE3336410A1 (de) * 1983-10-06 1985-04-18 Ludwig Heumann & Co GmbH, 8500 Nürnberg Sulfenamidderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3404786A1 (de) * 1984-02-10 1985-08-14 Ludwig Heumann & Co GmbH, 8500 Nürnberg Neue alkanolderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltendes arzneimittel
US4812451A (en) * 1984-10-19 1989-03-14 A. H. Robins Company, Incorporated 1-(aminoalkyl and aminoalkylamino)carbonyl and thiocarbonyl)-α,.alpha.
US4812452A (en) * 1984-10-19 1989-03-14 A. H. Robins Company, Incorporated 1-((aminoalkyl and aminoalkylamino) carbonyl and thiocarbonyl)-α,α-diarylpyrrolidine, piperidine and homopiperidineacetamides and acetonitriles
DE3568374D1 (en) * 1985-12-20 1989-03-30 Litef Gmbh Method to determine heading by using and automatically calibrating a 3-axis magnetometer rigidly fitted in an aircraft
US4988828A (en) * 1987-11-27 1991-01-29 Fujirebio Kabushiki Kaisha Phenoxypropyl derivatives
US5028716A (en) * 1989-01-30 1991-07-02 Taisho Pharmaceutical Co., Ltd. 3,5-diamino-1,2,4-triazole derivatives
GB9009437D0 (en) * 1990-04-26 1990-06-20 Glaxo Group Ltd Chemical compounds
WO2022034121A1 (fr) 2020-08-11 2022-02-17 Université De Strasbourg Bloqueurs de h2 ciblant des macrophages du foie pour la prévention et le traitement d'une maladie du foie et du cancer

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1419994A (en) 1973-05-03 1976-01-07 Smith Kline French Lab Heterocyclicalkylaminotheterocyclic compounds methods for their preparation and compositions comprising them
SU557574A1 (ru) 1975-07-02 1978-03-05 Ордена Трудового Красного Знамени Научно-Исследовательский Институт Экспериментальной Медицины Амн Ссср Способ получени 3-амино-5-(2-аминоэтил)-1,2,4-триазола
SU596577A1 (ru) 1976-02-23 1978-03-05 Ордена Трудового Красного Знамени Научно-Исследовательский Институт Экспериментальной Медицины -Метил- "/4-(5 амино-1,2,4триазолил-3)-бутил/-тиомочевина, про вл юща антигистаминовую активность, и способ ее получени
GB1565966A (en) * 1976-08-04 1980-04-23 Allen & Hanburys Ltd Aminoalkyl furan derivatives
IE46886B1 (en) * 1977-05-17 1983-10-19 Allen & Hanburys Ltd Aminoalkyl-benzene derivatives
GB1601459A (en) * 1977-05-17 1981-10-28 Allen & Hanburys Ltd Aminoalkyl thiophene derivatives
US4115860A (en) * 1977-06-02 1978-09-19 Lockheed Electronics Co., Inc. Plural load power controller with time-shared processor
DE2835695A1 (de) 1977-08-29 1979-03-15 Yamanouchi Pharma Co Ltd Neue heterocyclische verbindungen, verfahren zu ihrer herstellung und arzneimittel, die diese enthalten
AR228941A1 (es) * 1978-04-26 1983-05-13 Glaxo Group Ltd Procedimiento para preparar nuevos derivados de 3,5-diamino-1,2,4-triazol que son activos contra receptores histaminicos
US4293557A (en) * 1979-07-03 1981-10-06 Teikoku Hormone Mfg. Co., Ltd. Antiulcer phenoxypropylamine derivatives
DE3175201D1 (en) * 1980-04-30 1986-10-02 Merck & Co Inc Aminothiadiazoles as gastric secretion inhibitors
US4390701A (en) * 1981-05-18 1983-06-28 Bristol-Myers Company 1-Amino-2-[3-(3-piperidinomethylphenoxy)propylamino]cyclobutene-3,4-dione
GR77847B (fr) * 1981-12-14 1984-09-25 American Home Prod
JPS6067474A (ja) * 1983-09-24 1985-04-17 Wakamoto Pharmaceut Co Ltd 新規な１，３，４−チアジアゾ−ル誘導体及びそれを有効成分とする抗潰瘍剤
DE3513184A1 (de) * 1985-04-12 1986-10-16 Ludwig Heumann & Co GmbH, 8500 Nürnberg 1,3,4-thiadiazolderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Also Published As

Publication number Publication date
YU100379A (en) 1983-04-30
AT376212B (de) 1984-10-25
ES8101564A1 (es) 1980-12-16
PH19534A (en) 1986-05-20
US4318913A (en) 1982-03-09
ES488678A0 (es) 1980-12-16
NZ190299A (en) 1982-05-31
IL57178A (en) 1984-11-30
LU81192A1 (fr) 1980-05-07
ES8101565A1 (es) 1980-12-16
AR228941A1 (es) 1983-05-13
DE2954639C2 (fr) 1990-09-27
CH647767A5 (de) 1985-02-15
US4442110A (en) 1984-04-10
DE2917026A1 (de) 1979-11-08
ATA316679A (de) 1984-03-15
SE7903698L (sv) 1979-10-27
ES8101563A1 (es) 1980-12-16
AU531224B2 (en) 1983-08-18
DK173579A (da) 1979-10-27
ES488676A0 (es) 1980-12-16
FI791360A (fi) 1979-10-27
CA1143727A (fr) 1983-03-29
ES479988A0 (es) 1980-08-16
IT7948856A0 (it) 1979-04-26
FR2432511A1 (fr) 1980-02-29
ES8102104A1 (es) 1980-08-16
US4764612A (en) 1988-08-16
AU4648279A (en) 1979-11-01
NO791387L (no) 1979-10-29
ES488677A0 (es) 1980-12-16
YU16183A (en) 1983-04-30
IL57178A0 (en) 1979-07-25
IT1162304B (it) 1987-03-25
NL7903313A (nl) 1979-10-30

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Legal Events

Date Code Title Description
ST Notification of lapse