FR09C0062I2 - Anticorps de la il-1 beta humaine - Google Patents
Anticorps de la il-1 beta humaineInfo
- Publication number
- FR09C0062I2 FR09C0062I2 FR09C0062C FR09C0062C FR09C0062I2 FR 09C0062 I2 FR09C0062 I2 FR 09C0062I2 FR 09C0062 C FR09C0062 C FR 09C0062C FR 09C0062 C FR09C0062 C FR 09C0062C FR 09C0062 I2 FR09C0062 I2 FR 09C0062I2
- Authority
- FR
- France
- Prior art keywords
- human
- beta antibodies
- antibodies
- beta
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
- C07K16/245—IL-1
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Genetics & Genomics (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Ophthalmology & Optometry (AREA)
- Pain & Pain Management (AREA)
- Oncology (AREA)
- Urology & Nephrology (AREA)
- Gastroenterology & Hepatology (AREA)
- Communicable Diseases (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0020685.4A GB0020685D0 (en) | 2000-08-22 | 2000-08-22 | Organic compounds |
PCT/EP2001/009588 WO2002016436A2 (fr) | 2000-08-22 | 2001-08-20 | ANTICORPS DE LA IL-1β HUMAINE |
Publications (2)
Publication Number | Publication Date |
---|---|
FR09C0062I1 FR09C0062I1 (fr) | 2010-08-01 |
FR09C0062I2 true FR09C0062I2 (fr) | 2010-12-31 |
Family
ID=9898090
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR09C0062C Active FR09C0062I2 (fr) | 2000-08-22 | 2009-12-03 | Anticorps de la il-1 beta humaine |
Country Status (37)
Country | Link |
---|---|
US (3) | US7446175B2 (fr) |
EP (1) | EP1313769B2 (fr) |
JP (2) | JP4271936B2 (fr) |
KR (2) | KR20080056316A (fr) |
CN (1) | CN100547003C (fr) |
AR (1) | AR035581A1 (fr) |
AT (1) | ATE396206T1 (fr) |
AU (2) | AU9549001A (fr) |
BE (1) | BE2009C057I2 (fr) |
BR (1) | BR0113420A (fr) |
CA (1) | CA2420231C (fr) |
CY (2) | CY1108779T1 (fr) |
CZ (1) | CZ304470B6 (fr) |
DE (2) | DE122009000078I1 (fr) |
DK (1) | DK1313769T4 (fr) |
EC (1) | ECSP034490A (fr) |
ES (1) | ES2305110T5 (fr) |
FR (1) | FR09C0062I2 (fr) |
GB (1) | GB0020685D0 (fr) |
HK (1) | HK1061403A1 (fr) |
HU (2) | HU228159B1 (fr) |
IL (2) | IL154465A0 (fr) |
LU (1) | LU91624I2 (fr) |
MX (1) | MXPA03001590A (fr) |
MY (1) | MY130248A (fr) |
NL (1) | NL300427I1 (fr) |
NO (3) | NO332609B1 (fr) |
NZ (2) | NZ534269A (fr) |
PE (1) | PE20020319A1 (fr) |
PL (1) | PL212480B1 (fr) |
PT (1) | PT1313769E (fr) |
RU (1) | RU2286351C2 (fr) |
SI (1) | SI1313769T2 (fr) |
SK (1) | SK288089B6 (fr) |
TW (1) | TWI321568B (fr) |
WO (1) | WO2002016436A2 (fr) |
ZA (1) | ZA200301275B (fr) |
Families Citing this family (107)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1339426A4 (fr) * | 2000-11-08 | 2004-06-30 | Human Genome Sciences Inc | Anticorps a liaison immunospecifique avec les recepteurs "trail" |
CA2824167C (fr) * | 2002-09-06 | 2018-09-25 | Amgen Inc. | Anticorps monoclonal therapeutique anti-il-1r1 humain |
US7101978B2 (en) * | 2003-01-08 | 2006-09-05 | Applied Molecular Evolution | TNF-α binding molecules |
CA2509136C (fr) * | 2003-01-24 | 2013-10-29 | Applied Molecular Evolution, Inc. | Antagonistes de l'il-1 beta humaine |
GB0303337D0 (en) | 2003-02-13 | 2003-03-19 | Celltech R&D Ltd | Biological products |
US20040224893A1 (en) * | 2003-05-06 | 2004-11-11 | Li-Hsien Wang | Methods of using IL-1 antagonists to treat neointimal hyperplasia |
NZ549040A (en) * | 2004-02-17 | 2009-07-31 | Schering Corp | Use for interleukin-33 (IL33) and the IL-33 receptor complex |
AU2005216298B2 (en) | 2004-02-26 | 2010-09-02 | Baylor Research Institute | Compositions and methods for the systemic treatment of arthritis |
US7566772B2 (en) * | 2005-01-26 | 2009-07-28 | Amgen Fremont Inc. | Antibodies against interleukin-1β |
AU2012213934B9 (en) * | 2005-01-26 | 2013-07-25 | Amgen Fremont Inc. | Antibodies against interleukin-1 beta |
GB0509512D0 (en) * | 2005-05-10 | 2005-06-15 | Novartis Ag | Organic compounds |
HUE029021T2 (en) | 2005-06-21 | 2017-02-28 | Xoma (Us) Llc | IL-1beta-binding antibodies and fragments thereof |
WO2007042524A2 (fr) * | 2005-10-14 | 2007-04-19 | Novo Nordisk A/S | Traitement du diabete a l'aide d'inhibiteurs de l'il-1 |
DK2848258T3 (en) * | 2005-10-26 | 2018-03-19 | Novartis Ag | Treatment of familial Mediterranean fever with anti-IL-1beta antibodies |
US20100047204A1 (en) | 2006-04-14 | 2010-02-25 | Dana Sue Yoo | Use of organic compounds |
MX2009006709A (es) | 2006-12-20 | 2009-07-02 | Xoma Technology Ltd | Tratamiento de enfermedades relacionadas con il-1beta. |
CL2008001071A1 (es) * | 2007-04-17 | 2009-05-22 | Smithkline Beecham Corp | Metodo para obtener anticuerpo penta-especifico contra il-8/cxcl8, gro-alfa/cxcl1, gro-beta/cxcl2), gro-gama/cxcl3 y ena-78/cxcl5 humanas; anticuerpo penta-especifico; proceso de produccion del mismo; vector, hbridoma o celela que lo comprende; composicion farmceutica; uso para tratar copd, otras enfermedades. |
EP1997832A1 (fr) * | 2007-05-29 | 2008-12-03 | Ganymed Pharmaceuticals AG | Anticorps monoclonaux contre la claudine-18 pour le traitement contre le cancer |
US8282922B2 (en) * | 2007-05-29 | 2012-10-09 | Novartis Ag | Method of treating an auto-inflammatory syndrome with a human IL-1β binding antibody |
PT2391650E (pt) | 2007-12-20 | 2015-01-14 | Xoma Us Llc | Métodos para o tratamento de gota |
WO2009134776A2 (fr) | 2008-04-29 | 2009-11-05 | Abbott Laboratories | Immunoglobulines à double domaine variable et utilisations |
EP2297209A4 (fr) | 2008-06-03 | 2012-08-01 | Abbott Lab | Immunoglobulines à deux domaines variables et leurs utilisations |
SG191625A1 (en) | 2008-06-03 | 2013-07-31 | Abbott Lab | Dual variable domain immunoglobulins and uses thereof |
US20110189172A1 (en) * | 2008-06-06 | 2011-08-04 | Xoma Technology, Ltd. | Methods for the treatment of rheumatoid arthritis |
MX2010014574A (es) | 2008-07-08 | 2011-04-27 | Abbott Lab | Inmunoglobulinas de dominio variable dual para prostaglandina e2 y usos de las mismas. |
CA2735939A1 (fr) | 2008-09-05 | 2010-03-11 | Xoma Technology Ltd. | Procedes pour ameliorer la fonction des cellules beta |
MX2011004199A (es) * | 2008-10-20 | 2011-05-24 | Abbott Lab | Anticuerpos que unen a il-18 y metodos para purificar los mismos. |
US8298533B2 (en) * | 2008-11-07 | 2012-10-30 | Medimmune Limited | Antibodies to IL-1R1 |
EP2196476A1 (fr) * | 2008-12-10 | 2010-06-16 | Novartis Ag | Formulation d'anticorps |
EP2427209A1 (fr) * | 2009-05-06 | 2012-03-14 | Novartis AG | Thérapie par combinaison d'anticorps anti-il1- |
US8389474B1 (en) * | 2009-07-14 | 2013-03-05 | Alan Anson Wanderer | Rationale for IL-1 β targeted therapy to improve harvested organ viability, allograft tolerance, replant success and for conditions characterized by reduced or absent arterial perfusion |
CA2772628A1 (fr) * | 2009-09-01 | 2011-03-10 | Abbott Laboratories | Immunoglobulines a double domaine variable et leurs utilisations |
AU2010306677B2 (en) * | 2009-10-15 | 2013-05-23 | Abbvie Inc. | Dual variable domain immunoglobulins and uses thereof |
KR101860175B1 (ko) | 2009-10-26 | 2018-05-21 | 에프. 호프만-라 로슈 아게 | 글리코실화된 면역글로불린의 제조 방법 |
UY32979A (es) | 2009-10-28 | 2011-02-28 | Abbott Lab | Inmunoglobulinas con dominio variable dual y usos de las mismas |
EP2566520A4 (fr) | 2010-05-07 | 2014-02-12 | Xoma Us Llc | Méthodes de traitement d'affections associées à l'il-1 |
AU2011285852B2 (en) | 2010-08-03 | 2014-12-11 | Abbvie Inc. | Dual variable domain immunoglobulins and uses thereof |
BR112013004581A2 (pt) | 2010-08-26 | 2017-06-27 | Abbvie Inc | imunoglobulinas de domínio variável dual e seus usos |
US20140308294A1 (en) | 2011-04-15 | 2014-10-16 | Merck Patent Gmbh | Anti-IL-1R1 Inhibitors For Use in Cancer |
WO2013007763A1 (fr) | 2011-07-12 | 2013-01-17 | Universität Zürich | Modulateurs de la voie d'il-1β de l'inflammasome nlrp3 destiné à la prévention ou au traitement de l'acné |
DE102011083595A1 (de) | 2011-09-28 | 2013-03-28 | Bayer Pharma AG | Inhibition der Wirkung von Interleukin 1 beta zur Behandlung der Endometriose |
US9683038B2 (en) | 2011-09-30 | 2017-06-20 | Novartis Ag | Methods of reducing the risk of experiencing a cardiovascular (CV) event or a cerebrovascular event in a patient that has suffered a qualifying CV event |
WO2013082282A1 (fr) | 2011-12-02 | 2013-06-06 | lNOVARTIS AG | Thérapie prophylactique à base d'anticorps anti-il-1bêta (interleukine-1bêta) pour prévenir des complications conduisant à une vaso-occlusion dans une drépanocytose |
AU2012352168C1 (en) * | 2011-12-14 | 2018-01-25 | AbbVie Deutschland GmbH & Co. KG | Composition and method for the diagnosis and treatment of iron-related disorders |
EP2791171A1 (fr) | 2011-12-16 | 2014-10-22 | Synthon Biopharmaceuticals B.V. | Expression d'anticorps iga sécrétoires chez la lentille d'eau |
EP2794657B1 (fr) | 2011-12-19 | 2017-10-11 | Xoma (Us) Llc | Méthodes de traitement de l'acné |
WO2013102042A2 (fr) | 2011-12-30 | 2013-07-04 | Abbvie Inc. | Protéines à double liaison spécifique dirigées contre l'il-13 et/ou l'il-17 |
HUE049860T2 (hu) * | 2012-02-13 | 2020-11-30 | Agency Science Tech & Res | IL-ß-t neutralizáló, humán monoklonális antitestek |
CN103588878A (zh) * | 2012-08-15 | 2014-02-19 | 江苏泰康生物医药有限公司 | 一种人源化抗人白细胞介素1 β单克隆抗体及其制备与应用 |
KR20210111353A (ko) | 2012-11-01 | 2021-09-10 | 애브비 인코포레이티드 | 항-vegf/dll4 이원 가변 도메인 면역글로불린 및 이의 용도 |
BR112015009892B1 (pt) | 2012-11-05 | 2022-12-27 | Delenex Therapeutics Ag | Anticorpo contra il-1 beta, seu método de produção e seu uso, sequência isolada de ácido nucleico, vetor, composição cosmética, de diagnóstico ou farmacêutica, e kit |
US10000565B2 (en) | 2012-11-16 | 2018-06-19 | Novartis Ag | Use of IL-1 β binding antibodies for treating peripheral arterial disease |
EP4001307A1 (fr) | 2012-12-17 | 2022-05-25 | Cell Medica Inc. | Anticorps dirigés contre il-1 béta |
CN104995303A (zh) | 2012-12-18 | 2015-10-21 | 诺华股份有限公司 | 利用结合乙酰透明质酸的肽标签的组合物和方法 |
WO2014144280A2 (fr) | 2013-03-15 | 2014-09-18 | Abbvie Inc. | Protéines de liaison spécifiques à domaines variables doubles dirigées contre il -1β et/ou il -17 |
WO2015083120A1 (fr) | 2013-12-04 | 2015-06-11 | Novartis Ag | Utilisation d'anticorps de liaison à il-1β |
WO2015198243A2 (fr) | 2014-06-25 | 2015-12-30 | Novartis Ag | Compositions et procédés pour protéines à action longue |
WO2015198240A2 (fr) | 2014-06-25 | 2015-12-30 | Novartis Ag | Compositions et procédés permettant d'obtenir des protéines à action prolongée |
WO2016008851A1 (fr) * | 2014-07-14 | 2016-01-21 | Boehringer Ingelheim International Gmbh | Anticorps anti-il-1b |
MA41044A (fr) | 2014-10-08 | 2017-08-15 | Novartis Ag | Compositions et procédés d'utilisation pour une réponse immunitaire accrue et traitement contre le cancer |
MA40035A (fr) | 2014-10-14 | 2016-04-21 | Dana Farber Cancer Inst Inc | Molécules d'anticorps de pd-l1 et leurs utilisations |
CN107001456A (zh) | 2014-11-10 | 2017-08-01 | 豪夫迈·罗氏有限公司 | 抗ang2 抗体及使用方法 |
MX2017005977A (es) | 2014-11-10 | 2017-06-29 | Hoffmann La Roche | Anticuerpos biespecificos y metodos de uso en oftalmologia. |
US10093733B2 (en) | 2014-12-11 | 2018-10-09 | Abbvie Inc. | LRP-8 binding dual variable domain immunoglobulin proteins |
AU2016272900A1 (en) | 2015-06-04 | 2017-12-07 | Novartis Ag | Use of IL-1 beta binding antibodies to treat peripheral arterial disease |
TW201710286A (zh) | 2015-06-15 | 2017-03-16 | 艾伯維有限公司 | 抗vegf、pdgf及/或其受體之結合蛋白 |
EP3328418A1 (fr) | 2015-07-29 | 2018-06-06 | Novartis AG | Traitements combinés comprenant des molécules d'anticorps qui se lient à pd-1 |
US20180207273A1 (en) | 2015-07-29 | 2018-07-26 | Novartis Ag | Combination therapies comprising antibody molecules to tim-3 |
DK3317301T3 (da) | 2015-07-29 | 2021-06-28 | Immutep Sas | Kombinationsterapier omfattende antistofmolekyler mod lag-3 |
WO2017106656A1 (fr) | 2015-12-17 | 2017-06-22 | Novartis Ag | Molécules d'anticorps anti-pd-1 et leurs utilisations |
US11377656B2 (en) | 2016-03-10 | 2022-07-05 | Novartis Ag | Chemically modified messenger RNA's |
US20210292404A1 (en) | 2016-07-21 | 2021-09-23 | Novartis Ag | Use of il-1beta binding antibody canakinumab for treating or allevating symptoms pulmonary sarcoidosis |
WO2018106931A1 (fr) | 2016-12-07 | 2018-06-14 | Progenity Inc. | Procédés, dispositifs et systèmes de détection du tractus gastro-intestinal |
US20200315540A1 (en) | 2016-12-14 | 2020-10-08 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an il-1 inhibitor |
UY37758A (es) | 2017-06-12 | 2019-01-31 | Novartis Ag | Método de fabricación de anticuerpos biespecíficos, anticuerpos biespecíficos y uso terapéutico de dichos anticuerpos |
JP2020524694A (ja) | 2017-06-22 | 2020-08-20 | ノバルティス アーゲー | がんの処置における使用のためのIL−1β結合性抗体 |
WO2018235056A1 (fr) | 2017-06-22 | 2018-12-27 | Novartis Ag | Anticorps se liant à il-1beta destinés à être utilisés dans le traitement du cancer |
EP3655961A4 (fr) * | 2017-07-17 | 2021-09-01 | Massachusetts Institute of Technology | Atlas de cellules de tissus barrières sains et malades |
WO2019038740A1 (fr) | 2017-08-25 | 2019-02-28 | Novartis Ag | Utilisation de canakinumab |
BR112020004903A2 (pt) * | 2017-09-13 | 2020-09-15 | Novartis Ag | uso de anticorpos de ligação de il-1b para o tratamento de hepatite alcoólica |
MX2020004756A (es) | 2017-11-16 | 2020-08-20 | Novartis Ag | Terapias de combinacion. |
EP3790576A1 (fr) * | 2018-05-09 | 2021-03-17 | Novartis Ag | Utilisation de canakinumab |
EP3802611A2 (fr) | 2018-06-01 | 2021-04-14 | Novartis AG | Molécules de liaison dirigées contre bcma et leurs utilisations |
AR116109A1 (es) | 2018-07-10 | 2021-03-31 | Novartis Ag | Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos |
GB2575853A (en) * | 2018-07-25 | 2020-01-29 | Robert Wotherspoon Hugh | IL-1ß binding antibody |
CN110818793A (zh) * | 2018-08-14 | 2020-02-21 | 中山康方生物医药有限公司 | 抗IL-1β的抗体、其药物组合物及其用途 |
WO2020039401A1 (fr) | 2018-08-24 | 2020-02-27 | Novartis Ag | Traitement comprenant des anticorps se liant à il-1 βeta et ses combinaisons |
US11976115B2 (en) * | 2018-11-07 | 2024-05-07 | Zeda Biopharmaceuticals, Inc. | Antibody binding to human IL-1β, preparation method therefor and use thereof |
US20220249814A1 (en) | 2018-11-19 | 2022-08-11 | Progenity, Inc. | Methods and devices for treating a disease with biotherapeutics |
CN113271945A (zh) | 2018-12-20 | 2021-08-17 | 诺华股份有限公司 | 包含3-(1-氧代异吲哚啉-2-基)哌啶-2,6-二酮衍生物的给药方案和药物组合 |
EP3897613A1 (fr) | 2018-12-21 | 2021-10-27 | Novartis AG | Utilisation d'anticorps de liaison à il-1bêta |
GB201901187D0 (en) | 2019-01-29 | 2019-03-20 | Autolus Ltd | Treatment of neurotoxicity and/or cytokine release syndrome |
AU2020222346B2 (en) | 2019-02-15 | 2021-12-09 | Novartis Ag | Substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof |
WO2020165833A1 (fr) | 2019-02-15 | 2020-08-20 | Novartis Ag | Dérivés de 3-(1-oxo-5-(pipéridin-4-yl)isoindolin-2-yl)pipéridine-2,6-dione et leurs utilisations |
EP4073115A1 (fr) | 2019-12-09 | 2022-10-19 | Novartis AG | Anticorps anti-interleukine 1 bêta pour le traitement de la drépanocytose |
WO2021119482A1 (fr) | 2019-12-13 | 2021-06-17 | Progenity, Inc. | Dispositif ingérable pour administrer un agent thérapeutique dans le tractus gastro-intestinal |
TW202135858A (zh) | 2019-12-20 | 2021-10-01 | 瑞士商諾華公司 | 抗TGFβ抗體和檢查點抑制劑用於治療增殖性疾病之用途 |
TWI793503B (zh) * | 2020-01-20 | 2023-02-21 | 美商美國禮來大藥廠 | 抗IL-1β抗體 |
WO2021257539A1 (fr) * | 2020-06-16 | 2021-12-23 | Academia Sinica | ANTICORPS CIBLANT L'INTERLEUKIN-1β ET LEURS UTILISATIONS |
JP2023531676A (ja) | 2020-06-23 | 2023-07-25 | ノバルティス アーゲー | 3-(1-オキソイソインドリン-2-イル)ピぺリジン-2,6-ジオン誘導体を含む投与レジメン |
WO2022023907A1 (fr) | 2020-07-31 | 2022-02-03 | Novartis Ag | Méthodes de sélection et de traitement de patients présentant un risque élevé d'événements cardiaques indésirables majeurs |
CA3199095A1 (fr) | 2020-11-06 | 2022-05-12 | Novartis Ag | Molecules de liaison a cd19 et utilisations associees |
WO2022167916A1 (fr) | 2021-02-03 | 2022-08-11 | Novartis Ag | Utilisation d'anticorps se liant à l'il-1b pour le traitement de troubles neuro-inflammatoires |
TW202304979A (zh) | 2021-04-07 | 2023-02-01 | 瑞士商諾華公司 | 抗TGFβ抗體及其他治療劑用於治療增殖性疾病之用途 |
AR125874A1 (es) | 2021-05-18 | 2023-08-23 | Novartis Ag | Terapias de combinación |
CN117355323A (zh) | 2021-05-24 | 2024-01-05 | 诺华股份有限公司 | 用于治疗骨关节炎的方法 |
US20240294626A1 (en) | 2021-06-22 | 2024-09-05 | Novartis Ag | Bispecific antibodies for use in treatment of hidradenitis suppurativa |
Family Cites Families (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US534858A (en) * | 1895-02-26 | Workman s time-recorder | ||
CA1172789A (fr) | 1980-09-25 | 1984-08-14 | Hideo Kasahara | POLYMERE RENFERMANT UN POLYAMIDE LIE A UN COPOLYMERE QUI CONTIENT UN IMIDE D'ACIDE CARBOXYLIQUE INSATURE EN .alpha.,.beta. |
US4772685A (en) | 1985-10-02 | 1988-09-20 | Merck & Co., Inc. | Immunogenic peptides of human interleukin-1 and the corresponding anti-peptide antibodies |
GB8601597D0 (en) | 1986-01-23 | 1986-02-26 | Wilson R H | Nucleotide sequences |
US4935343A (en) * | 1986-08-08 | 1990-06-19 | Syntex (U.S.A.) Inc. | Monoclonal antibodies for interleukin-1β |
DE3785186T2 (de) | 1986-09-02 | 1993-07-15 | Enzon Lab Inc | Bindungsmolekuele mit einzelpolypeptidkette. |
DK590387A (da) | 1986-11-13 | 1988-05-14 | Otsuka Pharma Co Ltd | Antistoffer mod interleukin-1 |
GB8717430D0 (en) | 1987-07-23 | 1987-08-26 | Celltech Ltd | Recombinant dna product |
GB8809129D0 (en) | 1988-04-18 | 1988-05-18 | Celltech Ltd | Recombinant dna methods vectors and host cells |
EP0364778B1 (fr) | 1988-10-01 | 1996-03-13 | Otsuka Pharmaceutical Co., Ltd. | Anticorps contre l'interleukine-1 bêta |
GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
FR2640146B1 (fr) | 1988-12-08 | 1993-12-24 | Commissariat A Energie Atomique | Anticorps monoclonaux anti-interleukines 1(alpha) et 1(beta), leur procede de production et applications desdits anticorps a la detection des interleukines 1(alpha) et 1(beta) et en therapeutique |
IL162181A (en) | 1988-12-28 | 2006-04-10 | Pdl Biopharma Inc | A method of producing humanized immunoglubulin, and polynucleotides encoding the same |
CA2018248A1 (fr) | 1989-06-07 | 1990-12-07 | Clyde W. Shearman | Anticorps monoclonaux contre le recepteur alpha-beta de cellules t humaines, leur production et leur utilisation |
US5859205A (en) * | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
GB8928874D0 (en) | 1989-12-21 | 1990-02-28 | Celltech Ltd | Humanised antibodies |
ATE139258T1 (de) | 1990-01-12 | 1996-06-15 | Cell Genesys Inc | Erzeugung xenogener antikörper |
GB9014932D0 (en) | 1990-07-05 | 1990-08-22 | Celltech Ltd | Recombinant dna product and method |
US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
US5661016A (en) | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
US5633425A (en) | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
US5770429A (en) | 1990-08-29 | 1998-06-23 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
DE69127627T2 (de) | 1990-08-29 | 1998-02-19 | Genpharm Int | Produktion und Nützung nicht-menschliche transgentiere zur Produktion heterologe Antikörper |
JP3714683B2 (ja) * | 1992-07-30 | 2005-11-09 | 生化学工業株式会社 | 抗リウマチ剤 |
US5429614A (en) | 1993-06-30 | 1995-07-04 | Baxter International Inc. | Drug delivery system |
WO1995001997A1 (fr) * | 1993-07-09 | 1995-01-19 | Smithkline Beecham Corporation | ANTICORPS RECOMBINANTS ET HUMANISES, DIRIGES CONTRE L'IL-1β ET DESTINES AU TRAITEMENT DE TROUBLES INFLAMMATOIRES INDUITS PAR IL-1 CHEZ L'HOMME |
US6309636B1 (en) * | 1995-09-14 | 2001-10-30 | Cancer Research Institute Of Contra Costa | Recombinant peptides derived from the Mc3 anti-BA46 antibody, methods of use thereof, and methods of humanizing antibody peptides |
US6051228A (en) | 1998-02-19 | 2000-04-18 | Bristol-Myers Squibb Co. | Antibodies against human CD40 |
GB0001448D0 (en) | 2000-01-21 | 2000-03-08 | Novartis Ag | Organic compounds |
-
2000
- 2000-08-22 GB GBGB0020685.4A patent/GB0020685D0/en not_active Ceased
-
2001
- 2001-08-16 PE PE2001000817A patent/PE20020319A1/es not_active Application Discontinuation
- 2001-08-17 AR ARP010103946A patent/AR035581A1/es active IP Right Grant
- 2001-08-20 AU AU9549001A patent/AU9549001A/xx active Pending
- 2001-08-20 AU AU2001295490A patent/AU2001295490B2/en active Active
- 2001-08-20 DE DE122009000078C patent/DE122009000078I1/de active Pending
- 2001-08-20 NZ NZ534269A patent/NZ534269A/en not_active IP Right Cessation
- 2001-08-20 PL PL360358A patent/PL212480B1/pl unknown
- 2001-08-20 US US10/362,082 patent/US7446175B2/en not_active Expired - Lifetime
- 2001-08-20 PT PT01976118T patent/PT1313769E/pt unknown
- 2001-08-20 AT AT01976118T patent/ATE396206T1/de active
- 2001-08-20 SI SI200130844T patent/SI1313769T2/sl unknown
- 2001-08-20 NZ NZ524199A patent/NZ524199A/en not_active IP Right Cessation
- 2001-08-20 IL IL15446501A patent/IL154465A0/xx unknown
- 2001-08-20 CZ CZ2003-505A patent/CZ304470B6/cs unknown
- 2001-08-20 DK DK01976118.8T patent/DK1313769T4/da active
- 2001-08-20 KR KR1020087012282A patent/KR20080056316A/ko not_active Application Discontinuation
- 2001-08-20 JP JP2002521531A patent/JP4271936B2/ja not_active Expired - Lifetime
- 2001-08-20 EP EP01976118A patent/EP1313769B2/fr not_active Expired - Lifetime
- 2001-08-20 ES ES01976118T patent/ES2305110T5/es not_active Expired - Lifetime
- 2001-08-20 WO PCT/EP2001/009588 patent/WO2002016436A2/fr active IP Right Grant
- 2001-08-20 HU HU0300806A patent/HU228159B1/hu active Protection Beyond IP Right Term
- 2001-08-20 KR KR1020037002161A patent/KR100910789B1/ko active IP Right Grant
- 2001-08-20 BR BR0113420-5A patent/BR0113420A/pt not_active IP Right Cessation
- 2001-08-20 CA CA2420231A patent/CA2420231C/fr not_active Expired - Lifetime
- 2001-08-20 CN CNB018145140A patent/CN100547003C/zh not_active Expired - Lifetime
- 2001-08-20 MX MXPA03001590A patent/MXPA03001590A/es active IP Right Grant
- 2001-08-20 DE DE60134148T patent/DE60134148D1/de not_active Expired - Lifetime
- 2001-08-20 RU RU2003107564/13A patent/RU2286351C2/ru active Protection Beyond IP Right Term
- 2001-08-20 SK SK213-2003A patent/SK288089B6/sk not_active IP Right Cessation
- 2001-08-21 MY MYPI20013927A patent/MY130248A/en unknown
- 2001-08-22 TW TW090120626A patent/TWI321568B/zh not_active IP Right Cessation
-
2003
- 2003-02-13 IL IL154465A patent/IL154465A/en active Protection Beyond IP Right Term
- 2003-02-17 ZA ZA200301275A patent/ZA200301275B/en unknown
- 2003-02-19 EC EC2003004490A patent/ECSP034490A/es unknown
- 2003-02-21 NO NO20030827A patent/NO332609B1/no not_active IP Right Cessation
-
2004
- 2004-04-29 HK HK04103018.8A patent/HK1061403A1/xx not_active IP Right Cessation
-
2008
- 2008-08-01 JP JP2008199799A patent/JP2008295456A/ja active Pending
- 2008-08-11 CY CY20081100840T patent/CY1108779T1/el unknown
- 2008-09-26 US US12/238,502 patent/US7993878B2/en not_active Expired - Fee Related
-
2009
- 2009-11-24 NL NL300427C patent/NL300427I1/nl unknown
- 2009-11-25 LU LU91624C patent/LU91624I2/fr unknown
- 2009-11-30 BE BE2009C057C patent/BE2009C057I2/fr unknown
- 2009-12-03 FR FR09C0062C patent/FR09C0062I2/fr active Active
- 2009-12-09 CY CY2009019C patent/CY2009019I2/el unknown
-
2011
- 2011-06-29 US US13/171,631 patent/US8273350B2/en not_active Expired - Fee Related
-
2012
- 2012-11-21 NO NO2012018C patent/NO2012018I1/no unknown
-
2013
- 2013-04-26 HU HUS1300015C patent/HUS1300015I1/hu unknown
-
2017
- 2017-10-11 NO NO2017052C patent/NO2017052I2/no unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
FR09C0062I2 (fr) | Anticorps de la il-1 beta humaine | |
IS6779A (is) | Mannlíkt mótefni gegn LT-beta-R | |
NO20023266D0 (no) | Antistoffer mot humant IL-1 | |
DE60023971D1 (de) | Wegwerfunterwäsche | |
DE60129523D1 (de) | Wegwerfunterwäsche | |
DE60137900D1 (de) | Wegwerfunterwäsche | |
DE60104769D1 (de) | Wegwerfunterwäsche | |
NO20026063L (no) | Antistoffer mot human MCP-1 | |
DE60021475D1 (de) | Wegwerfwindel | |
DE60018509D1 (de) | Wegwerfwindel | |
DE60144260D1 (de) | Wegwerfwindel | |
DE60118469D1 (de) | Keramisches tragwerk | |
DE60125524D1 (de) | Wegwerfhöschen | |
DE60109968D1 (de) | Wegwerfwindel | |
DE60018495D1 (de) | Tamponeinführhilfe | |
DE60018142D1 (de) | Tamponapplikator | |
DE60129917D1 (de) | Wegwerfunterwäsche | |
DE60029737D1 (de) | Wegwerfwindel | |
DE60120890D1 (de) | Wegwerfwindel | |
DE60142667D1 (de) | Wegwerfunterwäsche | |
DE60232573D1 (de) | Damenbinde | |
ATE258035T1 (de) | Wegwerfartikel für menschliche fäkalien | |
DE60025251D1 (de) | Tamponapplikator | |
DE60014751D1 (de) | Wegwerfwindel | |
DE60105927D1 (de) | Wegwerfwindel |