FI970983A - Molekyylien siirto solujen sytoplasmaan - Google Patents
Molekyylien siirto solujen sytoplasmaan Download PDFInfo
- Publication number
- FI970983A FI970983A FI970983A FI970983A FI970983A FI 970983 A FI970983 A FI 970983A FI 970983 A FI970983 A FI 970983A FI 970983 A FI970983 A FI 970983A FI 970983 A FI970983 A FI 970983A
- Authority
- FI
- Finland
- Prior art keywords
- cells
- molecules
- cytoplasm
- transfer
- photodynamic treatment
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
- A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Catalysts (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NO943327A NO180167C (no) | 1994-09-08 | 1994-09-08 | Fotokjemisk fremgangsmåte til å innföre molekyler i cellers cytosol |
NO943327 | 1994-09-08 | ||
NO9500149 | 1995-09-04 | ||
PCT/NO1995/000149 WO1996007432A1 (en) | 1994-09-08 | 1995-09-04 | Transfer of molecules into the cytosol of cells |
Publications (3)
Publication Number | Publication Date |
---|---|
FI970983A true FI970983A (fi) | 1997-03-07 |
FI970983A0 FI970983A0 (fi) | 1997-03-07 |
FI121328B FI121328B (fi) | 2010-10-15 |
Family
ID=19897382
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI970983A FI121328B (fi) | 1994-09-08 | 1997-03-07 | Molekyylien siirto solujen sytosoliin |
Country Status (20)
Country | Link |
---|---|
US (3) | US5876989A (fi) |
EP (1) | EP0783323B1 (fi) |
JP (1) | JP4148328B2 (fi) |
KR (2) | KR100529967B1 (fi) |
CN (1) | CN1222309C (fi) |
AT (1) | ATE209507T1 (fi) |
AU (1) | AU700797B2 (fi) |
BR (1) | BRPI9508825B8 (fi) |
CA (1) | CA2199290C (fi) |
CZ (1) | CZ65897A3 (fi) |
DE (1) | DE69524238T2 (fi) |
ES (1) | ES2163527T3 (fi) |
FI (1) | FI121328B (fi) |
HK (1) | HK1004110A1 (fi) |
HU (1) | HU222984B1 (fi) |
MX (1) | MX9701676A (fi) |
NO (1) | NO180167C (fi) |
NZ (2) | NZ293008A (fi) |
PT (1) | PT783323E (fi) |
WO (1) | WO1996007432A1 (fi) |
Families Citing this family (83)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NO180167C (no) | 1994-09-08 | 1997-02-26 | Photocure As | Fotokjemisk fremgangsmåte til å innföre molekyler i cellers cytosol |
US6176842B1 (en) * | 1995-03-08 | 2001-01-23 | Ekos Corporation | Ultrasound assembly for use with light activated drugs |
US6210356B1 (en) * | 1998-08-05 | 2001-04-03 | Ekos Corporation | Ultrasound assembly for use with a catheter |
ATE409005T1 (de) * | 1997-03-19 | 2008-10-15 | Lucid Inc | Zellchirurgie unter benutzung konfokaler mikroskopie |
US6676626B1 (en) | 1998-05-01 | 2004-01-13 | Ekos Corporation | Ultrasound assembly with increased efficacy |
US6582392B1 (en) | 1998-05-01 | 2003-06-24 | Ekos Corporation | Ultrasound assembly for use with a catheter |
JP2002500201A (ja) * | 1998-01-05 | 2002-01-08 | ユニバーシティ オブ ワシントン | 膜破壊剤を使用する増強された輸送 |
US6399769B1 (en) * | 1998-01-20 | 2002-06-04 | Kimberly-Clark Worldwide, Inc. | Method of making sulfanatophenyl substituted porphines |
GB9905911D0 (en) | 1999-03-15 | 1999-05-05 | Photocure As | Method |
WO2001019953A1 (fr) * | 1999-09-09 | 2001-03-22 | Center For Advanced Science And Technology Incubation, Ltd. | Procede de perçage de membrane et appareil a cet effet |
US7807780B2 (en) * | 2000-07-21 | 2010-10-05 | Revance Therapeutics, Inc. | Multi-component biological transport systems |
US20040220100A1 (en) * | 2000-07-21 | 2004-11-04 | Essentia Biosystems, Inc. | Multi-component biological transport systems |
PL213560B1 (pl) * | 2000-11-29 | 2013-03-29 | Pci Biotech As | Sposób wprowadzania czasteczki do cytozolu komórki in vitro lub ex vivo, zastosowanie medyczne oraz kompozycja |
KR101180548B1 (ko) * | 2000-11-29 | 2012-09-06 | 피씨아이 바이오테크 에이에스 | 사이토졸 내로의 바이러스 매개된 분자 전달을 위한 광화학적 내부이행 |
US20020098472A1 (en) * | 2000-11-30 | 2002-07-25 | Erlach Julian Van | Method for inserting a microdevice or a nanodevice into a body fluid stream |
US20020137901A1 (en) * | 2001-01-22 | 2002-09-26 | Cavanaugh Philip Gerard | Synthesis, and photodynamic therapy-mediated anti-cancer, and other uses of chlorin e6-transferrin |
US20030031655A1 (en) * | 2001-02-08 | 2003-02-13 | Sequitur, Inc. | Methods of light activated release of ligands from endosomes |
JP4081436B2 (ja) * | 2001-06-20 | 2008-04-23 | 大日本住友製薬株式会社 | 核酸導入を促進させる方法 |
GB0121023D0 (en) | 2001-08-30 | 2001-10-24 | Norwegian Radium Hospital Res | Compound |
EP1647232B1 (en) | 2001-12-03 | 2011-08-17 | Ekos Corporation | Catheter with multiple ultrasound radiating members |
US7141044B2 (en) * | 2001-12-11 | 2006-11-28 | Ekos Corporation | Alternate site gene therapy |
US20060009409A1 (en) | 2002-02-01 | 2006-01-12 | Woolf Tod M | Double-stranded oligonucleotides |
WO2003064621A2 (en) * | 2002-02-01 | 2003-08-07 | Ambion, Inc. | HIGH POTENCY siRNAS FOR REDUCING THE EXPRESSION OF TARGET GENES |
DK2128248T4 (en) | 2002-02-01 | 2017-03-13 | Life Technologies Corp | Oligonucleotide compositions with increased efficiency |
US8226629B1 (en) | 2002-04-01 | 2012-07-24 | Ekos Corporation | Ultrasonic catheter power control |
US20040248094A1 (en) * | 2002-06-12 | 2004-12-09 | Ford Lance P. | Methods and compositions relating to labeled RNA molecules that reduce gene expression |
GB0215534D0 (en) * | 2002-07-04 | 2002-08-14 | Ecole Polytech | Selective photochemotherapy using oligonucleotide targeting agents |
US20040029275A1 (en) * | 2002-08-10 | 2004-02-12 | David Brown | Methods and compositions for reducing target gene expression using cocktails of siRNAs or constructs expressing siRNAs |
US6921371B2 (en) * | 2002-10-14 | 2005-07-26 | Ekos Corporation | Ultrasound radiating members for catheter |
EP1587908A4 (en) * | 2003-01-09 | 2008-02-20 | Invitrogen Corp | RELEASE AND ACTIVATION OF COMPLEX CELLS OF POLYPEPTIDES AND NUCLEIC ACIDS |
US7332477B2 (en) * | 2003-07-10 | 2008-02-19 | Nitto Denko Corporation | Photocleavable DNA transfer agent |
JP4586022B2 (ja) * | 2003-09-29 | 2010-11-24 | 日東電工株式会社 | インビボポリヌクレオチド送達用生分解性ポリアセタール |
US20080318319A1 (en) * | 2003-12-19 | 2008-12-25 | Yoshiko Minakuchi | Novel Method of Nucleic Acid Transfer |
CA2558676C (en) * | 2004-03-03 | 2019-04-16 | Essentia Biosystems, Inc. | Compositions and methods for topical diagnostic and therapeutic transport |
ES2554821T3 (es) * | 2004-03-03 | 2015-12-23 | Revance Therapeutics, Inc. | Aplicación tópica y liberación transdérmica de toxinas botulínicas |
US9211248B2 (en) | 2004-03-03 | 2015-12-15 | Revance Therapeutics, Inc. | Compositions and methods for topical application and transdermal delivery of botulinum toxins |
GB0415263D0 (en) * | 2004-07-07 | 2004-08-11 | Norwegian Radium Hospital Res | Method |
US20060094781A1 (en) * | 2004-11-04 | 2006-05-04 | Syneron Medical Ltd. | Method of treating extracellular matrix |
FR2877943B1 (fr) * | 2004-11-16 | 2008-09-05 | Univ De Coimbra | Nouveaux derives de porphyrine, notamment chlorines et/ou bacteriochlorine, et leurs applications en therapie photodynamique |
US20090247464A1 (en) | 2005-03-03 | 2009-10-01 | Revance Therapeutics, Inc. | Compositions and Methods for Topical Application and Transdermal Delivery of an Oligopeptide |
RU2007136616A (ru) | 2005-03-03 | 2009-04-10 | Риванс Терапьютикс, Инк. (Us) | Композиция и способ для местного применения и чрескожного введения ботулинового токсина |
US7674452B2 (en) * | 2005-03-16 | 2010-03-09 | Nitto Denko Corporation | Polymer coating of cells |
BRPI0501037B8 (pt) | 2005-03-18 | 2021-07-27 | Fund De Amparo A Pesquisa Do Estado De Sao Paulo | uso de crotamina e composição |
KR101423272B1 (ko) * | 2005-11-17 | 2014-07-30 | 레반스 테라퓨틱스, 아이엔씨. | 감소된 비-독소 단백질을 갖는 보툴리눔 독소의 국소 적용및 경피 전달을 위한 조성물 및 방법 |
WO2007109584A1 (en) * | 2006-03-16 | 2007-09-27 | University Of Washington | Temperature-and ph-responsive polymer compositions |
GB0613753D0 (en) * | 2006-07-11 | 2006-08-23 | Norwegian Radium Hospital Res | Method |
AU2007333225B2 (en) * | 2006-12-08 | 2014-06-12 | Massachusetts Institute Of Technology | Delivery of nanoparticles and/or agents to cells |
CN102988995A (zh) * | 2006-12-29 | 2013-03-27 | 雷文斯治疗公司 | 用源自hiv-tat的多肽片段稳定的肉毒杆菌毒素的组合物及其局部施用和透皮递送的方法 |
US20100093639A1 (en) * | 2006-12-29 | 2010-04-15 | Revance Therapeutics, Inc. | Transport Molecules Using Reverse Sequence HIV-TAT Polypeptides |
US10182833B2 (en) | 2007-01-08 | 2019-01-22 | Ekos Corporation | Power parameters for ultrasonic catheter |
US7981688B2 (en) | 2007-03-08 | 2011-07-19 | University Of Washington | Stimuli-responsive magnetic nanoparticles and related methods |
EP2494932B1 (en) | 2007-06-22 | 2020-05-20 | Ekos Corporation | Apparatus for treatment of intracranial hemorrhages |
US20090187137A1 (en) * | 2007-12-14 | 2009-07-23 | Kim Volz | Ultrasound pulse shaping |
GB0811955D0 (en) | 2008-06-30 | 2008-07-30 | Pci Biotech As | Method |
US8426214B2 (en) * | 2009-06-12 | 2013-04-23 | University Of Washington | System and method for magnetically concentrating and detecting biomarkers |
GB0914286D0 (en) | 2009-08-14 | 2009-09-30 | Pci Biotech As | Method |
GB0914287D0 (en) | 2009-08-14 | 2009-09-30 | Pci Biotech As | Compositions |
US9080933B2 (en) | 2009-11-09 | 2015-07-14 | University Of Washington Through Its Center For Commercialization | Stimuli-responsive polymer diagnostic assay comprising magnetic nanoparticles and capture conjugates |
US20110117668A1 (en) * | 2009-11-09 | 2011-05-19 | University Of Washington Through Its Center For Commercialization | Self-powered smart diagnostic devices |
GB201208548D0 (en) * | 2012-05-15 | 2012-06-27 | Pci Biotech As | Compound and method |
US20160040128A1 (en) | 2013-03-15 | 2016-02-11 | Pci Biotech As | Method |
GB2517707B (en) | 2013-08-28 | 2020-09-02 | Pci Biotech As | A device for light-induced rupture of endocytic vesicles to effect the delivery of an antigen |
WO2015028574A1 (en) | 2013-08-28 | 2015-03-05 | Pci Biotech As | Compound and method for vaccination and immunisation |
WO2015154832A1 (en) | 2014-04-11 | 2015-10-15 | Pci Biotech As | Method of treating melanoma |
EP3185901B1 (en) | 2014-08-28 | 2023-10-04 | PCI Biotech AS | Compound and method |
GB201503776D0 (en) | 2015-03-05 | 2015-04-22 | Pci Biotech As | Compound and method |
WO2016201136A1 (en) | 2015-06-10 | 2016-12-15 | Ekos Corporation | Ultrasound catheter |
KR20190068573A (ko) | 2016-10-14 | 2019-06-18 | 피씨아이 바이오테크 에이에스 | 젬시타빈의 tpcs-2a 유도된 광화학 내재화로의 담관암의 치료 |
GB201718631D0 (en) | 2017-11-10 | 2017-12-27 | Pci Biotech As | Method |
GB201801169D0 (en) * | 2018-01-24 | 2018-03-07 | Pci Biotech As | Method |
WO2020017962A1 (en) | 2018-07-16 | 2020-01-23 | Dcprime B.V. | A combination product for use in tumor vaccination. |
AU2020264083A1 (en) | 2019-04-25 | 2021-12-02 | Mendus B.V. | Methods of tumor vaccination |
CN110711249B (zh) * | 2019-09-19 | 2020-10-27 | 北京化工大学 | 一种溶酶体膜包覆纳米颗粒的制备方法 |
CA3172447A1 (en) | 2020-03-27 | 2021-09-30 | Erik Hans MANTING | In vivo use of modified cells of leukemic origin for enhancing the efficacy of adoptive cell therapy |
WO2021191870A1 (en) | 2020-03-27 | 2021-09-30 | Dcprime B.V. | Ex vivo use of modified cells of leukemic origin for enhancing the efficacy of adoptive cell therapy |
CN114163508B (zh) * | 2020-09-11 | 2024-07-16 | 王月志 | 能破坏细胞的氨基酸序列及相关核苷酸序列和相关的应用 |
CA3196677A1 (en) | 2020-11-05 | 2022-05-12 | Erik Hans MANTING | Use of tumor-independent antigens in immunotherapies |
GB202101726D0 (en) | 2021-02-08 | 2021-03-24 | Pci Biotech As | Method |
EP4304633A1 (en) | 2021-03-12 | 2024-01-17 | Mendus B.V. | Methods of vaccination and use of cd47 blockade |
GB202115451D0 (en) | 2021-10-27 | 2021-12-08 | Pci Biotech As | Method |
WO2024068795A1 (en) | 2022-09-27 | 2024-04-04 | Pci Biotech As | Method for releasing viral vectors |
GB202301312D0 (en) | 2023-01-30 | 2023-03-15 | Pci Biotech As | Method and product |
GB202404168D0 (en) | 2024-03-22 | 2024-05-08 | Pci Biotech As | Method |
Family Cites Families (41)
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AU563827B2 (en) | 1982-07-01 | 1987-07-23 | Millipore Corp. | Filtration apparatus |
US4649151A (en) * | 1982-09-27 | 1987-03-10 | Health Research, Inc. | Drugs comprising porphyrins |
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GB8916859D0 (en) | 1989-07-24 | 1989-09-06 | Dynal As | Hapten linking |
GB8929297D0 (en) | 1989-12-29 | 1990-02-28 | Dynal As | Method of separation |
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NO180167C (no) | 1994-09-08 | 1997-02-26 | Photocure As | Fotokjemisk fremgangsmåte til å innföre molekyler i cellers cytosol |
US5872007A (en) * | 1995-02-17 | 1999-02-16 | Hybridon, Inc. | CAPL-specific oligonucleotides and methods of inhibiting metastatic cancer |
-
1994
- 1994-09-08 NO NO943327A patent/NO180167C/no not_active IP Right Cessation
-
1995
- 1995-09-04 ES ES95932244T patent/ES2163527T3/es not_active Expired - Lifetime
- 1995-09-04 HU HU9800153A patent/HU222984B1/hu active IP Right Grant
- 1995-09-04 JP JP50940496A patent/JP4148328B2/ja not_active Expired - Fee Related
- 1995-09-04 DE DE69524238T patent/DE69524238T2/de not_active Expired - Lifetime
- 1995-09-04 BR BRPI9508825A patent/BRPI9508825B8/pt not_active IP Right Cessation
- 1995-09-04 NZ NZ293008A patent/NZ293008A/en not_active IP Right Cessation
- 1995-09-04 WO PCT/NO1995/000149 patent/WO1996007432A1/en not_active Application Discontinuation
- 1995-09-04 US US08/793,794 patent/US5876989A/en not_active Expired - Lifetime
- 1995-09-04 NZ NZ509519A patent/NZ509519A/en not_active IP Right Cessation
- 1995-09-04 AT AT95932244T patent/ATE209507T1/de active
- 1995-09-04 EP EP95932244A patent/EP0783323B1/en not_active Expired - Lifetime
- 1995-09-04 PT PT95932244T patent/PT783323E/pt unknown
- 1995-09-04 CN CNB951960652A patent/CN1222309C/zh not_active Expired - Lifetime
- 1995-09-04 CA CA2199290A patent/CA2199290C/en not_active Expired - Lifetime
- 1995-09-04 MX MX9701676A patent/MX9701676A/es unknown
- 1995-09-04 AU AU35347/95A patent/AU700797B2/en not_active Expired
- 1995-09-04 CZ CZ97658A patent/CZ65897A3/cs unknown
- 1995-09-14 KR KR10-2003-7005142A patent/KR100529967B1/ko not_active IP Right Cessation
- 1995-09-14 KR KR1019970701520A patent/KR100395615B1/ko active IP Right Grant
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1997
- 1997-03-07 FI FI970983A patent/FI121328B/fi not_active IP Right Cessation
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1998
- 1998-04-24 HK HK98103468A patent/HK1004110A1/xx not_active IP Right Cessation
- 1998-09-01 US US09/144,750 patent/US6680301B2/en not_active Expired - Fee Related
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2002
- 2002-11-01 US US10/286,632 patent/US20030134813A1/en not_active Abandoned
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