FI945289A - Kontraseptiomenetelmä, jossa käytetään kilpailevia progesteroniantagonisteja, ja menetelmässä käyttökelpoisia uusia yhdisteitä - Google Patents
Kontraseptiomenetelmä, jossa käytetään kilpailevia progesteroniantagonisteja, ja menetelmässä käyttökelpoisia uusia yhdisteitä Download PDFInfo
- Publication number
- FI945289A FI945289A FI945289A FI945289A FI945289A FI 945289 A FI945289 A FI 945289A FI 945289 A FI945289 A FI 945289A FI 945289 A FI945289 A FI 945289A FI 945289 A FI945289 A FI 945289A
- Authority
- FI
- Finland
- Prior art keywords
- progesterone antagonists
- novel compounds
- compounds useful
- contraceptive
- 11beta
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
- C07J53/002—Carbocyclic rings fused
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Gynecology & Obstetrics (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigation Of Foundation Soil And Reinforcement Of Foundation Soil By Compacting Or Drainage (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nozzles (AREA)
- Mixers With Rotating Receptacles And Mixers With Vibration Mechanisms (AREA)
- Orthopedics, Nursing, And Contraception (AREA)
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4216004A DE4216004B4 (de) | 1992-05-12 | 1992-05-12 | Verwendung kompetitiver Progesteronantagonisten |
DE19924216003 DE4216003A1 (de) | 1992-05-12 | 1992-05-12 | Dissoziierte kompetitive Progesteronantagonisten |
DE4216003 | 1992-05-12 | ||
DE4216004 | 1992-05-12 | ||
EP9301181 | 1993-05-12 | ||
PCT/EP1993/001181 WO1993023020A1 (en) | 1992-05-12 | 1993-05-12 | Contraception method using competitive progesterone antagonists and novel compounds useful therein |
Publications (3)
Publication Number | Publication Date |
---|---|
FI945289A0 FI945289A0 (fi) | 1994-11-10 |
FI945289A true FI945289A (fi) | 1994-11-10 |
FI112167B FI112167B (fi) | 2003-11-14 |
Family
ID=25914813
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI945289A FI112167B (fi) | 1992-05-12 | 1994-11-10 | Dissosioituneiden kilpailevien progesteroniantagonistien käyttö ehkäisyaineen valmistamiseksi ja käyttökelpoisia uusia yhdisteitä |
Country Status (29)
Country | Link |
---|---|
US (5) | US5439913A (fi) |
EP (1) | EP0639970B2 (fi) |
JP (1) | JPH07506582A (fi) |
KR (1) | KR100253922B1 (fi) |
CN (1) | CN1059446C (fi) |
AT (1) | ATE162712T1 (fi) |
AU (1) | AU687000B2 (fi) |
BG (1) | BG61965B1 (fi) |
BR (1) | BR9306354A (fi) |
CA (1) | CA2135608C (fi) |
CZ (1) | CZ290612B6 (fi) |
DE (1) | DE69316747T3 (fi) |
DK (1) | DK0639970T4 (fi) |
ES (1) | ES2114605T5 (fi) |
FI (1) | FI112167B (fi) |
GR (1) | GR3026316T3 (fi) |
HU (1) | HUT68061A (fi) |
IL (1) | IL105684A (fi) |
MX (1) | MX9302748A (fi) |
MY (1) | MY108866A (fi) |
NO (1) | NO307691B1 (fi) |
NZ (1) | NZ252154A (fi) |
PH (1) | PH29913A (fi) |
PL (1) | PL173337B1 (fi) |
RO (1) | RO116769B1 (fi) |
RU (1) | RU2137476C1 (fi) |
SK (1) | SK282531B6 (fi) |
UA (1) | UA39934C2 (fi) |
WO (1) | WO1993023020A1 (fi) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX9301121A (es) | 1992-03-02 | 1993-09-01 | Schering Ag | Metodo y equipo para la contracepcion oral y regulacion de la menstruacion con estrogeno/progestina/aniprogestina. |
US7704983B1 (en) | 1992-03-02 | 2010-04-27 | Eastern Virginia Medical School | Antiprogestin method for reducing side effects associated with low dosage HRT and oral contraception |
US5439913A (en) * | 1992-05-12 | 1995-08-08 | Schering Aktiengesellschaft | Contraception method using competitive progesterone antagonists and novel compounds useful therein |
DE4344463A1 (de) * | 1993-12-22 | 1995-06-29 | Schering Ag | Kombinationsprodukt zur Kontrazeption |
FR2718138B1 (fr) * | 1994-04-01 | 1996-04-26 | Roussel Uclaf | Nouveaux stéroïdes comportant en position 20 une chaîne aminosubstituée, procédé et intermédiaires de préparation, application comme médicaments et compositions pharmaceutiques les renfermant. |
DE4417880A1 (de) * | 1994-05-18 | 1995-11-23 | Schering Ag | 19,11beta-Überbrückte 18-Nor-Steroide, Verfahren zu ihrer Herstellung, diese Steroide enthaltende Arzneimittel sowie deren Verwendung zur Herstellung von Arzneimitteln |
PT787002E (pt) * | 1994-10-24 | 2007-03-30 | Schering Ag | Antagonistas de progesterona competitivos para controlo de fertilidade feminina orientado pela necessidade |
ZA9510926B (en) | 1994-12-23 | 1996-07-03 | Schering Ag | Compounds with progesterone-antagonistic and antiestrogenic action to be used together for female contraception |
DE19652408C2 (de) * | 1996-12-06 | 2002-04-18 | Schering Ag | Steroidester, Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung von Arzneimitteln |
CA2255130A1 (en) | 1997-12-16 | 1999-06-16 | Archer Daniels Midland Company | Process for making granular l-lysine feed supplement |
US20020169205A1 (en) * | 1998-09-29 | 2002-11-14 | Krzysztof Chwalisz | Implantation rates after in vitro fertilization, and treatment of infertility and early pregnancy loss with a nitric oxide donor or substrate alone or in combination with progesterone, and a method for contraception with nitric oxide inhibitors in combination with antiprogestins or other agents |
EE200200103A (et) | 1999-08-31 | 2003-04-15 | Jenapharm Gmbh & Co. Kg | Mesoprogestiinid (progesterooniretseptori modulaatorid) naise kontratseptiivide komponendina |
US7317027B2 (en) * | 2003-05-19 | 2008-01-08 | Sanofi-Aventis Deutschland Gmbh | Azaindole-derivatives as factor Xa inhibitors |
US20050090475A1 (en) * | 2003-10-01 | 2005-04-28 | Laguardia Katherine D. | Extended triphasic contraceptive regimens |
US20060205700A1 (en) * | 2005-03-09 | 2006-09-14 | May Flavia S | Non invasive method for prevention and treatment of cancer |
PL2078032T3 (pl) | 2006-10-24 | 2018-01-31 | Repros Therapeutics Inc | Kompozycje i sposoby do hamowania proliferacji endometrium |
DE102007049630A1 (de) | 2007-10-11 | 2009-10-29 | Bayer Schering Pharma Aktiengesellschaft | Nichtsteroidale Progesteronrezeptor-Modulatoren |
DE102007023614A1 (de) | 2007-05-21 | 2008-11-27 | Bayer Schering Pharma Aktiengesellschaft | Nichtsteroidale Progesteronrezeptor-Modulatoren |
DE102007032800A1 (de) | 2007-07-10 | 2009-01-15 | Bayer Schering Pharma Aktiengesellschaft | Nichtsteroidale Progesteronrezeptor-Modulatoren |
DE102007058747A1 (de) | 2007-12-05 | 2009-06-10 | Bayer Schering Pharma Aktiengesellschaft | Nichtsteroidale Progesteronrezeptor-Modulatoren |
EP2070909A1 (de) | 2007-12-15 | 2009-06-17 | Bayer Schering Pharma AG | Nichtsteroidale Progesteronrezeptor-Modulatoren |
TWI539953B (zh) | 2008-04-28 | 2016-07-01 | 瑞波若斯治療學公司 | 用於治療乳癌之組成物和方法 |
TWI477276B (zh) * | 2008-04-28 | 2015-03-21 | Repros Therapeutics Inc | 抗黃體素給藥方案 |
SG183924A1 (en) | 2010-03-22 | 2012-10-30 | Repros Therapeutics Inc | Compositions and methods for non-toxic delivery of antiprogestins |
WO2011150209A1 (en) | 2010-05-26 | 2011-12-01 | Corcept Therapeutics, Inc. | Treatment of muscular dystrophy |
US9381193B2 (en) * | 2011-04-01 | 2016-07-05 | Washington University | Contraceptive methods and compositions |
EP2868323A1 (en) | 2013-11-03 | 2015-05-06 | Flamina Holding AG | A pharmaceutical composition or group of compositions for inhibiting autocrine HCG production in adult human cells |
EP2868321A1 (en) | 2013-11-03 | 2015-05-06 | Flamina Holding AG | A composition or group of compositions for inhibiting autocrine HCG production in adult human cells |
JP6821582B2 (ja) | 2015-03-02 | 2021-01-27 | コーセプト セラピューティクス, インコーポレイテッド | Acth分泌腫瘍を処置するための糖質コルチコイドレセプターアンタゴニストおよびソマトスタチンアナログの使用 |
AU2016243625B2 (en) | 2015-03-30 | 2020-09-10 | Corcept Therapeutics, Inc. | Use of glucocorticoid receptor antagonists in combination with glucocorticoids to treat adrenal insufficiency |
KR20180052120A (ko) | 2015-08-13 | 2018-05-17 | 코어셉트 쎄라퓨틱스, 잉크. | Acth-의존성 쿠싱 증후군을 감별 진단하는 방법 |
MX2018008849A (es) | 2016-01-19 | 2019-01-31 | Corcept Therapeutics Inc | Diagnostico diferencial de sindrome de cushing ectopico. |
SG11201908790PA (en) | 2017-03-31 | 2019-10-30 | Corcept Therapeutics Inc | Glucocorticoid receptor modulators to treat cervical cancer |
EP3641780A4 (en) | 2017-06-20 | 2021-02-24 | Corcept Therapeutics, Inc. | TREATMENT METHODS OF NEURO-EPITHELIAL TUMORS USING SELECTIVE GLUCOCORTICOID RECEPTOR MODULATORS |
CA3205462A1 (en) | 2020-12-18 | 2022-06-23 | Instil Bio (Uk) Limited | Processing of tumor infiltrating lymphocytes |
Family Cites Families (41)
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DE219447C (fi) * | ||||
DE283428C (fi) * | 1913-12-10 | 1915-04-15 | ||
US3890356A (en) | 1973-03-26 | 1975-06-17 | Richardson Merrell Inc | 7-Alkyl-{66 {hu 3,5{b -steroids |
US3928398A (en) | 1973-11-01 | 1975-12-23 | Richardson Merrell Inc | Derivatives of 7{60 -methylestr-4-en-3{60 ,17{62 -diol |
US4000273A (en) | 1973-11-01 | 1976-12-28 | Richardson-Merrell Inc. | Method for the control of fertility |
US4352751A (en) | 1979-09-10 | 1982-10-05 | Analytical Radiation Corporation | Species-linked diamine triacetic acids and their chelates |
US4416622A (en) * | 1980-11-25 | 1983-11-22 | F. L. Smidth & Co. | Method and plant such as a kiln plant for treating granular or pulverous raw material |
ZA8231B (en) | 1981-01-09 | 1982-11-24 | Roussel Uclaf | New 11 -substituted steroid derivatives, their preparation, their use as medicaments, the compositions containing them and the new intermediates thus obtained |
US4957939A (en) | 1981-07-24 | 1990-09-18 | Schering Aktiengesellschaft | Sterile pharmaceutical compositions of gadolinium chelates useful enhancing NMR imaging |
US4647447A (en) | 1981-07-24 | 1987-03-03 | Schering Aktiengesellschaft | Diagnostic media |
US4416822A (en) | 1982-07-09 | 1983-11-22 | The Upjohn Company | 17β-Difluoromethyl steroids |
IL68222A (en) | 1983-03-24 | 1987-02-27 | Yeda Res & Dev | Contraceptive compositions comprising a progesterone antagonist and a blocker of progesterone activity |
ES8502612A1 (es) | 1983-06-15 | 1985-02-01 | Schering Ag | Procedimiento para la preparacion de 13a-alquilgonanos |
DE3324235A1 (de) | 1983-07-01 | 1985-01-10 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue komplexbildner, komplexe und komplexsalze |
AU572589B2 (en) | 1983-12-14 | 1988-05-12 | Upjohn Company, The | 11(alpha)-difluoromethyl and (e)-and (z)-11-fluoromethylene steroids |
DE3347126A1 (de) | 1983-12-22 | 1985-07-11 | Schering AG, 1000 Berlin und 4709 Bergkamen | 11ss-aryl-estradiene, deren herstellung und diese enthaltende pharmazeutische praeparate |
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DE3533175A1 (de) * | 1985-09-13 | 1987-03-19 | Schering Ag | Antigestagene zur verschiebung der endometrialen reifung |
DE3625315A1 (de) | 1986-07-25 | 1988-01-28 | Schering Ag | 11ss-(4-isopropenylphenyl)-estra-4,9-diene, deren herstellung und diese enthaltende pharmazeutische praeparate |
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US4994259A (en) | 1987-05-08 | 1991-02-19 | Salutar, Inc. | Improvement in the method of NMR imaging employing a manganese II chelates of N,N'-bis[pyridoxal-alkylene (or cycloalkylene) (or arylene)]-N,N'-diacetic acid derivatives |
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DE3805064A1 (de) * | 1988-02-18 | 1989-10-05 | Hoechst Ag | Pharmazeutische zubereitungen zur geburtseinleitung, fuer den schwangerschaftsabbruch und zur verwendung als kontrazeptivum |
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GB8923843D0 (en) | 1989-10-23 | 1989-12-13 | Salutar Inc | Compounds |
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US5407928A (en) | 1990-08-15 | 1995-04-18 | Schering Aktiengesellschaft | 11β-aryl-gona-4,9-dien-3-ones |
IE71203B1 (en) | 1990-12-13 | 1997-02-12 | Akzo Nv | Low estrogen oral contraceptives |
US5439913A (en) | 1992-05-12 | 1995-08-08 | Schering Aktiengesellschaft | Contraception method using competitive progesterone antagonists and novel compounds useful therein |
AU1918092A (en) | 1992-05-06 | 1993-11-29 | Medical College Of Hampton Roads, The | Minimizing progestin associated breakthrough bleeding |
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US5516769A (en) | 1993-02-19 | 1996-05-14 | The Medical College Of Hampton Roads | Method of inhibiting fertilization |
-
1992
- 1992-07-01 US US07/907,514 patent/US5439913A/en not_active Expired - Lifetime
-
1993
- 1993-05-11 PH PH46174A patent/PH29913A/en unknown
- 1993-05-11 MX MX9302748A patent/MX9302748A/es not_active IP Right Cessation
- 1993-05-12 SK SK1347-94A patent/SK282531B6/sk unknown
- 1993-05-12 DK DK93909968T patent/DK0639970T4/da active
- 1993-05-12 BR BR9306354A patent/BR9306354A/pt not_active Application Discontinuation
- 1993-05-12 IL IL10568493A patent/IL105684A/en not_active IP Right Cessation
- 1993-05-12 AT AT93909968T patent/ATE162712T1/de not_active IP Right Cessation
- 1993-05-12 MY MYPI93000880A patent/MY108866A/en unknown
- 1993-05-12 NZ NZ252154A patent/NZ252154A/en not_active IP Right Cessation
- 1993-05-12 EP EP93909968A patent/EP0639970B2/en not_active Expired - Lifetime
- 1993-05-12 WO PCT/EP1993/001181 patent/WO1993023020A1/en active IP Right Grant
- 1993-05-12 HU HU9403253A patent/HUT68061A/hu unknown
- 1993-05-12 CZ CZ19942780A patent/CZ290612B6/cs not_active IP Right Cessation
- 1993-05-12 DE DE69316747T patent/DE69316747T3/de not_active Expired - Fee Related
- 1993-05-12 AU AU40673/93A patent/AU687000B2/en not_active Ceased
- 1993-05-12 ES ES93909968T patent/ES2114605T5/es not_active Expired - Lifetime
- 1993-05-12 RO RO94-01791A patent/RO116769B1/ro unknown
- 1993-05-12 CN CN93107323A patent/CN1059446C/zh not_active Expired - Fee Related
- 1993-05-12 CA CA002135608A patent/CA2135608C/en not_active Expired - Fee Related
- 1993-05-12 RU RU94046068A patent/RU2137476C1/ru not_active IP Right Cessation
- 1993-05-12 PL PL93306094A patent/PL173337B1/pl not_active IP Right Cessation
- 1993-05-12 JP JP5519879A patent/JPH07506582A/ja active Pending
- 1993-12-05 UA UA94105922A patent/UA39934C2/uk unknown
-
1994
- 1994-11-10 FI FI945289A patent/FI112167B/fi active
- 1994-11-11 NO NO944308A patent/NO307691B1/no unknown
- 1994-11-11 KR KR1019940704038A patent/KR100253922B1/ko not_active IP Right Cessation
- 1994-11-11 BG BG99178A patent/BG61965B1/bg unknown
-
1998
- 1998-03-11 GR GR980400507T patent/GR3026316T3/el unknown
- 1998-09-17 US US09/154,755 patent/US6340688B1/en not_active Expired - Fee Related
-
2001
- 2001-11-28 US US09/994,781 patent/US6608074B2/en not_active Expired - Fee Related
-
2003
- 2003-03-31 US US10/401,598 patent/US6790853B2/en not_active Expired - Fee Related
-
2004
- 2004-07-15 US US10/891,180 patent/US7297702B2/en not_active Expired - Fee Related
Also Published As
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