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MX9302748A - Metodo anticonceptivo que usa antagonistas de progesterona y compuestos novedosos utiles para lo mismo. - Google Patents

Metodo anticonceptivo que usa antagonistas de progesterona y compuestos novedosos utiles para lo mismo.

Info

Publication number
MX9302748A
MX9302748A MX9302748A MX9302748A MX9302748A MX 9302748 A MX9302748 A MX 9302748A MX 9302748 A MX9302748 A MX 9302748A MX 9302748 A MX9302748 A MX 9302748A MX 9302748 A MX9302748 A MX 9302748A
Authority
MX
Mexico
Prior art keywords
useful
progesterone antagonists
same
11beta
17alpha
Prior art date
Application number
MX9302748A
Other languages
English (en)
Inventor
Ulrich Klar
Horst Michna
Krzysztof Chwalisz
Karin Schmidt Gollwitzer
Eckhard Ottow
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25914813&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX9302748(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE4216004A external-priority patent/DE4216004B4/de
Priority claimed from DE19924216003 external-priority patent/DE4216003A1/de
Application filed by Schering Ag filed Critical Schering Ag
Publication of MX9302748A publication Critical patent/MX9302748A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Gynecology & Obstetrics (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigation Of Foundation Soil And Reinforcement Of Foundation Soil By Compacting Or Drainage (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Nozzles (AREA)
  • Mixers With Rotating Receptacles And Mixers With Vibration Mechanisms (AREA)

Abstract

La presente invención se refiere a antagonistas de progesterona competitivas, incluyendo dos esteroides novedosos, por ejemplo 11beta, 19 (4-(cianofeninil)-o-fenileno)-17beta-hidroxi-17ak fa-(3-hidroxiprop-1-(z)-enil)-4-androsten-3-ona y 11beta, 19 (4-(piridinil)-o-fenileno-)- 17beta-hidro-xi-17alfa-(3-hidroxiprop-1-(Z)-enil)- 4-androsten-3-ona, para inhibir la formación de las glándulas endometriales, por abajo de su dosis de inhibición de la ovulación, y la dosis abortiva , y por lo tanto se logra la anticoncepción en hembras sin afectar adversamente, el ciclo menstrual, y sin el riesgo de abortar un óvulo fertilizado implantado o su feto.
MX9302748A 1992-05-12 1993-05-11 Metodo anticonceptivo que usa antagonistas de progesterona y compuestos novedosos utiles para lo mismo. MX9302748A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4216004A DE4216004B4 (de) 1992-05-12 1992-05-12 Verwendung kompetitiver Progesteronantagonisten
DE19924216003 DE4216003A1 (de) 1992-05-12 1992-05-12 Dissoziierte kompetitive Progesteronantagonisten

Publications (1)

Publication Number Publication Date
MX9302748A true MX9302748A (es) 1994-02-28

Family

ID=25914813

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9302748A MX9302748A (es) 1992-05-12 1993-05-11 Metodo anticonceptivo que usa antagonistas de progesterona y compuestos novedosos utiles para lo mismo.

Country Status (29)

Country Link
US (5) US5439913A (es)
EP (1) EP0639970B2 (es)
JP (1) JPH07506582A (es)
KR (1) KR100253922B1 (es)
CN (1) CN1059446C (es)
AT (1) ATE162712T1 (es)
AU (1) AU687000B2 (es)
BG (1) BG61965B1 (es)
BR (1) BR9306354A (es)
CA (1) CA2135608C (es)
CZ (1) CZ290612B6 (es)
DE (1) DE69316747T3 (es)
DK (1) DK0639970T4 (es)
ES (1) ES2114605T5 (es)
FI (1) FI112167B (es)
GR (1) GR3026316T3 (es)
HU (1) HUT68061A (es)
IL (1) IL105684A (es)
MX (1) MX9302748A (es)
MY (1) MY108866A (es)
NO (1) NO307691B1 (es)
NZ (1) NZ252154A (es)
PH (1) PH29913A (es)
PL (1) PL173337B1 (es)
RO (1) RO116769B1 (es)
RU (1) RU2137476C1 (es)
SK (1) SK282531B6 (es)
UA (1) UA39934C2 (es)
WO (1) WO1993023020A1 (es)

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ZA959008B (en) * 1994-10-24 1996-09-16 Schering Ag Competitive progesterone antagonists for demand-oriented female birth control
ZA9510926B (en) 1994-12-23 1996-07-03 Schering Ag Compounds with progesterone-antagonistic and antiestrogenic action to be used together for female contraception
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US20020169205A1 (en) * 1998-09-29 2002-11-14 Krzysztof Chwalisz Implantation rates after in vitro fertilization, and treatment of infertility and early pregnancy loss with a nitric oxide donor or substrate alone or in combination with progesterone, and a method for contraception with nitric oxide inhibitors in combination with antiprogestins or other agents
UA77150C2 (en) 1999-08-31 2006-11-15 Schering Ag Use of mesoprogestins j867, j912, or j1042 for female contraception, pharmaceutical composition and kit (variants)
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CA2978960C (en) 2015-03-30 2023-05-02 Corcept Therapeutics, Inc. Use of glucocorticoid receptor antagonists in combination with glucocorticoids to treat adrenal insufficiency
KR20180052120A (ko) 2015-08-13 2018-05-17 코어셉트 쎄라퓨틱스, 잉크. Acth-의존성 쿠싱 증후군을 감별 진단하는 방법
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Also Published As

Publication number Publication date
DK0639970T4 (da) 2003-02-10
CA2135608C (en) 2007-04-10
US20030191102A1 (en) 2003-10-09
UA39934C2 (uk) 2001-07-16
BG61965B1 (bg) 1998-11-30
US20050026885A1 (en) 2005-02-03
KR100253922B1 (en) 2000-09-01
FI112167B (fi) 2003-11-14
SK134794A3 (en) 1998-05-06
DK0639970T3 (da) 1998-09-21
DE69316747D1 (de) 1998-03-05
CN1087643A (zh) 1994-06-08
EP0639970B2 (en) 2002-11-06
CZ278094A3 (en) 1995-02-15
HUT68061A (en) 1995-05-29
SK282531B6 (sk) 2002-10-08
US6340688B1 (en) 2002-01-22
IL105684A0 (en) 1993-09-22
US6790853B2 (en) 2004-09-14
ATE162712T1 (de) 1998-02-15
RU2137476C1 (ru) 1999-09-20
FI945289A0 (fi) 1994-11-10
WO1993023020A1 (en) 1993-11-25
DE69316747T2 (de) 1998-09-24
CA2135608A1 (en) 1993-11-25
CN1059446C (zh) 2000-12-13
ES2114605T3 (es) 1998-06-01
CZ290612B6 (cs) 2002-09-11
IL105684A (en) 1998-08-16
RU94046068A (ru) 1996-10-20
AU687000B2 (en) 1998-02-19
US20020058649A1 (en) 2002-05-16
ES2114605T5 (es) 2003-04-16
FI945289A (fi) 1994-11-10
NZ252154A (en) 1996-04-26
BG99178A (bg) 1995-05-31
EP0639970B1 (en) 1998-01-28
BR9306354A (pt) 1998-06-30
NO944308D0 (no) 1994-11-11
US7297702B2 (en) 2007-11-20
US5439913A (en) 1995-08-08
PH29913A (en) 1996-09-16
GR3026316T3 (en) 1998-06-30
NO307691B1 (no) 2000-05-15
RO116769B1 (ro) 2001-06-29
AU4067393A (en) 1993-12-13
US6608074B2 (en) 2003-08-19
PL173337B1 (pl) 1998-02-27
DE69316747T3 (de) 2003-04-10
NO944308L (no) 1995-01-11
JPH07506582A (ja) 1995-07-20
EP0639970A1 (en) 1995-03-01
MY108866A (en) 1996-11-30

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MM Annulment or lapse due to non-payment of fees