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FI20041124A - Valintamerkkigeenittömät yhdistelmäkannat, menetelmä niiden valmistamiseksi, ja näiden kantojen käyttö - Google Patents

Valintamerkkigeenittömät yhdistelmäkannat, menetelmä niiden valmistamiseksi, ja näiden kantojen käyttö Download PDF

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Publication number
FI20041124A
FI20041124A FI20041124A FI20041124A FI20041124A FI 20041124 A FI20041124 A FI 20041124A FI 20041124 A FI20041124 A FI 20041124A FI 20041124 A FI20041124 A FI 20041124A FI 20041124 A FI20041124 A FI 20041124A
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FI
Finland
Prior art keywords
strains
selection marker
preparation
marker gene
dna
Prior art date
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FI20041124A
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English (en)
Swedish (sv)
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FI117388B (fi
Inventor
Gerardus Cornelis Maria Selten
Bart Willem Swinkels
Gorcom Robertus Franciscus Van
Original Assignee
Dsm Ip Assets Bv
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Application filed by Dsm Ip Assets Bv filed Critical Dsm Ip Assets Bv
Publication of FI20041124A publication Critical patent/FI20041124A/fi
Application granted granted Critical
Publication of FI117388B publication Critical patent/FI117388B/fi

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/65Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression using markers

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  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
FI20041124A 1993-07-23 2004-08-27 Valintamerkkigeenittömät hiivakannat, menetelmä niiden valmistamiseksi ja näiden kantojen käyttö FI117388B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP93202195 1993-07-23
EP93202195 1993-07-23

Publications (2)

Publication Number Publication Date
FI20041124A true FI20041124A (fi) 2004-08-27
FI117388B FI117388B (fi) 2006-09-29

Family

ID=8214006

Family Applications (2)

Application Number Title Priority Date Filing Date
FI943485A FI114481B (fi) 1993-07-23 1994-07-22 Valintamerkkigeenittömät rihmasienikannat, menetelmä niiden valmistamiseksi, ja näiden kantojen käyttö
FI20041124A FI117388B (fi) 1993-07-23 2004-08-27 Valintamerkkigeenittömät hiivakannat, menetelmä niiden valmistamiseksi ja näiden kantojen käyttö

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FI943485A FI114481B (fi) 1993-07-23 1994-07-22 Valintamerkkigeenittömät rihmasienikannat, menetelmä niiden valmistamiseksi, ja näiden kantojen käyttö

Country Status (13)

Country Link
US (3) US5876988A (fi)
EP (2) EP0635574B1 (fi)
JP (2) JP3833725B2 (fi)
CN (1) CN100347301C (fi)
AT (1) ATE238425T1 (fi)
BR (1) BR9402912A (fi)
CA (1) CA2128589C (fi)
DE (1) DE69432543T2 (fi)
DK (1) DK0635574T3 (fi)
ES (1) ES2198410T3 (fi)
FI (2) FI114481B (fi)
IE (1) IE20030875A1 (fi)
NZ (2) NZ299139A (fi)

Families Citing this family (170)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL1003096C2 (nl) * 1995-05-15 1996-11-19 Gist Brocades Bv Application of phospholipases in animal feed.
WO1997000962A1 (en) 1995-06-23 1997-01-09 Danisco Ingredients A/S (Danisco A/S) A novel method to isolate mutants and to clone the complementing gene
AU721471B2 (en) 1995-08-03 2000-07-06 Gist-Brocades B.V. The use of homologous amdS genes as selectable markers
DK0814165T3 (da) * 1996-06-21 2003-07-21 Suntory Ltd Fremgangsmåde til konstruktion af transformerede gærceller, der ikke indeholder et selekterbart markørgen
US6265186B1 (en) 1997-04-11 2001-07-24 Dsm N.V. Yeast cells comprising at least two copies of a desired gene integrated into the chromosomal genome at more than one non-ribosomal RNA encoding domain, particularly with Kluyveromyces
JP5303084B2 (ja) 1997-04-11 2013-10-02 コニンクリーケ デーエスエム ナムローゼ フェンノートシャップ 工業的組み換え生物を溝築するための手段としての遺伝子変換
WO1998046774A1 (en) * 1997-04-11 1998-10-22 Dsm N.V. Yeast cells comprising at least two copies of a desired gene integrated into the chromosomal genome at more than one non-ribosomal rna encoding domain, particularly with kluyveromyces
NZ502444A (en) 1997-07-31 2001-11-30 Dsm N Polypeptides with cellobiohydrolase activity (CBH A and CBH B) from Aspergillus
CA2313445C (en) * 1997-12-22 2012-03-20 Dsm N.V. Expression cloning in filamentous fungi
EP1040197A1 (en) * 1997-12-22 2000-10-04 Unilever N.V. A process for site-directed integration of multiple copies of a gene in a mould
ES2302379T3 (es) 1998-05-19 2008-07-01 Dsm Ip Assets B.V. Produccion in vivo mejorada de cefalosporina.
US6358705B1 (en) 1998-07-16 2002-03-19 Novo Nordisk A/S Method of making proteins in transformed yeast cells
BR9912106B1 (pt) * 1998-07-16 2012-09-04 processo para fazer um polipeptìdeo ou proteìna desejados em uma cepa de levedura saccharomyces.
US7220542B2 (en) 2000-07-17 2007-05-22 Van Den Brink Johannes Maarten Expression cloning in filamentous fungi
US6750379B2 (en) 2000-03-09 2004-06-15 Dekalb Genetics Corporation Homologous recombination-mediated transgene alterations in plants
CZ2003798A3 (cs) 2000-09-21 2003-08-13 Dsm N. V. Polypeptid s aktivitou xylanázy, sekvence nukleové kyseliny kódující polypeptid, způsob přípravy a použití polypeptidu
JP4334352B2 (ja) 2002-01-23 2009-09-30 ロイヤル ネダルコ ベスローテン フェンノートシャップ ペントース糖の発酵
US7517671B2 (en) 2002-02-28 2009-04-14 New England Biolabs, Inc. Methods and compositions for concentrating secreted recombinant protein
TWI328612B (en) 2002-07-25 2010-08-11 Dsm Ip Assets Bv Genes and their encoded polypeptides involved in the biosynthetic pathway of vitamin b12, vectors and host cells comprising the genes, and process for producing vitamin b12
EP1565561A1 (en) * 2002-11-28 2005-08-24 Universiteit Leiden A method for marker-less integration of a sequence of interest into the genome of a cell
CN1795197B (zh) 2003-05-28 2010-06-02 帝斯曼知识产权资产管理有限公司 头孢菌素类化合物
CN1298213C (zh) * 2003-09-10 2007-02-07 王海波 一种通过分割处理获得无选择标记转基因植物的方法
EP1673380A2 (en) * 2003-10-14 2006-06-28 DSM IP Assets B.V. Method for preparing a modified host cell
ES2350048T3 (es) 2004-04-02 2011-01-17 Dsm Ip Assets B.V. Mutantes fúngicos filamentosos con eficiencia mejorada de recombinación homóloga.
JP4783359B2 (ja) 2004-04-16 2011-09-28 ディーエスエム アイピー アセッツ ビー.ブイ. 真菌細胞において遺伝子を発現させるための真菌プロモーター
JP2008516594A (ja) * 2004-10-15 2008-05-22 ディーエスエム アイピー アセッツ ビー.ブイ. 選択可能なマーカーとしての相同性amds遺伝子
US20090017061A1 (en) 2005-01-18 2009-01-15 Bernard Jan Appelmelk Mycobacteria with Mannose Cap-Deficient Lipoarabinomannan
EP2410048B1 (en) 2005-01-24 2016-08-10 DSM IP Assets B.V. Method for producing a compound of interest in a filamentous fungal cell
EP1954812B1 (en) 2005-11-29 2012-11-21 DSM IP Assets B.V. Dna binding site of a transcriptional activator useful in gene expression
BRPI0619091A2 (pt) 2005-12-01 2011-09-13 Dsm Ip Assests Bv novos genes úteis para a produção industrial de ácido cìtrico
PL2423315T3 (pl) 2006-06-29 2015-06-30 Dsm Ip Assets Bv Sposób osiągania lepszej ekspresji polipeptydu
EP2511372A1 (en) 2006-11-02 2012-10-17 DSM IP Assets B.V. Improved production of secreted proteins by filamentous fungi
EP2631295A3 (en) 2007-02-15 2014-01-01 DSM IP Assets B.V. A recombinant host cell for the production of a compound of interest
EP2126100B1 (en) 2007-03-21 2012-11-14 DSM IP Assets B.V. Improved method for homologous recombination
BRPI0819717B1 (pt) 2007-11-20 2022-05-17 Dsm Ip Assets B.V. Levedura recombinante e processo para a produção de ácido succínico
ES2383473T3 (es) 2007-11-20 2012-06-21 Dsm Ip Assets B.V. Producción de ácido dicarboxílico en eucariotas
EP2222854A1 (en) 2007-11-20 2010-09-01 DSM IP Assets B.V. Dicarboxylic acid production in a filamentous fungus
WO2009078712A2 (en) 2007-12-17 2009-06-25 Universiteit Van Amsterdam Light-driven co2 reduction to organic compounds to serve as fuels or as industrial half products by an autotroph containing a fermentative gene cassette
FR2927089B1 (fr) 2008-02-05 2011-03-25 Inst Nat De La Rech Agronomique Inra Procede d'integration ciblee de multicopies d'un gene d'interet dans une souche de yarrowia
EP2116136A1 (en) 2008-05-08 2009-11-11 Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO Novel phytases
WO2010004141A2 (fr) * 2008-07-11 2010-01-14 Institut National De La Recherche Agronomique (Inra) Nouvelles souches de levure mutantes capables d'accumuler une grande quantité de lipides
CN102099466A (zh) * 2008-07-29 2011-06-15 丹尼斯科美国公司 在丝状真菌细胞中增加天冬氨酸蛋白酶的产生
EP2310487A2 (en) 2008-08-05 2011-04-20 DSM IP Assets B.V. Adipoyl-7-adca producing strains
US8703463B2 (en) 2009-03-10 2014-04-22 Dsm Ip Assets B.V. Pregastric esterase and derivatives thereof
AU2010223354A1 (en) 2009-03-10 2011-09-08 Dsm Ip Assets B.V. Method for improving the yield of a polypeptide
WO2010107310A1 (en) 2009-03-17 2010-09-23 Nederlandse Organisatie Voor Toegepast- Natuurwetenschappelijk Onderzoek Tno Novel cellulose and ligno-cellulose active proteins
EP2419518A1 (en) 2009-04-15 2012-02-22 DSM IP Assets B.V. Dicarboxylic acid production process
CN102414323B (zh) 2009-04-22 2015-07-08 帝斯曼知识产权资产管理有限公司 用于生产感兴趣的重组多肽的方法
CN102439145B (zh) 2009-04-24 2014-02-19 帝斯曼知识产权资产管理有限公司 降解碳水化合物的多肽及其用途
UA108853C2 (uk) 2009-07-10 2015-06-25 Спосіб ферментації галактози
EP2456872B1 (en) 2009-07-22 2017-08-30 DSM IP Assets B.V. Improved host cell for the production of a compound of interest
JP2013507939A (ja) 2009-10-22 2013-03-07 ビーエーエスエフ ソシエタス・ヨーロピア 合成フィターゼ変異体
CN102597213A (zh) * 2009-11-04 2012-07-18 帝斯曼知识产权资产管理有限公司 篮状菌转化体
US20130011876A1 (en) 2010-02-04 2013-01-10 Dsm Ip Assetts, B.V. Process for preparing filamentous fungal strains having a sexual cycle and a process for preparing sexually crossed filamentous fungal strains
US9133448B2 (en) 2010-02-11 2015-09-15 Dsm Ip Assets B.V. Polypeptide having cellobiohydrolase activity and uses thereof
MX2012009274A (es) 2010-02-11 2012-12-05 Dsm Ip Assets Bv Celula hospedera capaz de producir enzimas utiles para la degradacion de material lignocelulosico.
JP2013524796A (ja) 2010-04-21 2013-06-20 ディーエスエム アイピー アセッツ ビー.ブイ. 混合糖組成物の発酵に適した細胞
EP2388331A1 (en) 2010-05-21 2011-11-23 Nederlandse Organisatie voor toegepast -natuurwetenschappelijk onderzoek TNO Constitutive promoter
WO2012000886A1 (en) 2010-06-29 2012-01-05 Dsm Ip Assets B.V. Polypeptide having beta-glucosidase activity and uses thereof
WO2012000890A1 (en) 2010-06-29 2012-01-05 Dsm Ip Assets B.V. Polypeptide having beta-glucosidase activity and uses thereof
BR112012033714A2 (pt) 2010-06-29 2016-02-16 Dsm Ip Assets Bv polipeptídeo com atividade de acetil xilano esterase e seus usos.
CN103180337A (zh) 2010-06-29 2013-06-26 帝斯曼知识产权资产管理有限公司 具有膨胀因子活性的多肽及其用途
PL2588603T3 (pl) 2010-06-29 2017-08-31 Dsm Ip Assets B.V. Polipeptyd mający lub wzmacniający aktywność degradacji materiału węglowodanowego i jego zastosowania
WO2012000891A1 (en) 2010-06-29 2012-01-05 Dsm Ip Assets B.V. Polypeptide having carbohydrate degrading activity and uses thereof
DK2588616T3 (en) 2010-07-01 2019-03-11 Dsm Ip Assets Bv PROCEDURE FOR MAKING A RELATIONSHIP OF INTEREST
MX2013004127A (es) 2010-10-13 2013-05-20 Dsm Ip Assets Bv Polipeptidos con actividad permeasa.
DK2683732T3 (en) 2011-03-11 2016-12-12 Dsm Ip Assets Bv Vector-host-system
EP2699674B1 (en) 2011-04-21 2016-01-06 Basf Se Synthetic phytase variants
EP2699589A2 (en) 2011-04-22 2014-02-26 DSM IP Assets B.V. Yeast cell capable of converting sugars including arabinose and xylose
EP2554668A1 (en) 2011-08-04 2013-02-06 DSM IP Assets B.V. A pentose sugar fermenting cell
AR087423A1 (es) 2011-08-04 2014-03-19 Dsm Ip Assets Bv Celula capaz de fermentar azucares pentosas
CA2862980A1 (en) 2012-01-23 2013-08-01 Dsm Ip Assets B.V. Diterpene production
CN104508114A (zh) 2012-06-19 2015-04-08 帝斯曼知识产权资产管理有限公司 用于在细胞中表达基因的启动子
IN2014DN11163A (fi) 2012-07-19 2015-10-02 Dsm Ip Assets Bv
US10273507B2 (en) 2012-10-16 2019-04-30 Dsm Ip Assets B.V. Cells with improved pentose conversion
WO2014096436A1 (en) * 2012-12-21 2014-06-26 Estibio Aps Marker-free genetically-engineered double mutants of thermoanaerobacter
EP3686280B1 (en) 2013-02-04 2022-06-22 DSM IP Assets B.V. Carbohydrate degrading polypeptide and uses thereof
EP2772545A1 (en) 2013-03-01 2014-09-03 Nederlandse Organisatie voor toegepast -natuurwetenschappelijk onderzoek TNO Starch active proteins
WO2014142647A1 (en) 2013-03-14 2014-09-18 Wageningen Universiteit Fungals strains with improved citric acid and itaconic acid production
US20160060660A1 (en) 2013-04-05 2016-03-03 Université Du Luxembourg Biotechnological production of itaconic acid
MX2015015274A (es) 2013-05-02 2016-05-26 Dutch Dna Biotech B V Ruta de ácido organico novedosa.
WO2014191581A2 (en) 2013-05-31 2014-12-04 Dsm Ip Assets B.V. Microorganisms for diterpene production
WO2014202624A2 (en) 2013-06-19 2014-12-24 Dsm Ip Assets B.V. Rasamsonia gene and use thereof
WO2014202622A2 (en) 2013-06-19 2014-12-24 Dsm Ip Assets B.V. Rasamsonia gene and use thereof
WO2014202620A2 (en) 2013-06-19 2014-12-24 Dsm Ip Assets B.V. Rasamsonia gene and use thereof
WO2014202621A1 (en) 2013-06-20 2014-12-24 Dsm Ip Assets B.V. Carbohydrate degrading polypeptide and uses thereof
EP3885443A1 (en) 2013-07-15 2021-09-29 DSM IP Assets B.V. Diterpene production
BR112016002092B1 (pt) 2013-07-31 2020-12-15 Dsm Ip Assets B.V. Recuperação de glicosídeos de esteviol
US10487125B2 (en) 2013-12-02 2019-11-26 Dsm Ip Assets B.V. Ice structuring protein
WO2016012429A1 (en) 2014-07-24 2016-01-28 Dsm Ip Assets B.V. Yeast cell with improved pentose transport
FR3028527A1 (fr) 2014-11-13 2016-05-20 Pivert Identification de facteurs de transcription de yarrowia lipolytica
DK3242950T3 (da) 2015-01-06 2021-12-20 Dsm Ip Assets Bv Crispr-cas-system til en trådformet svampeværtscelle
DK3242948T3 (da) 2015-01-06 2022-03-07 Dsm Ip Assets Bv Crispr-cas-system til en yarrowia-værtscelle
DK3242949T3 (da) 2015-01-06 2022-01-24 Dsm Ip Assets Bv Crispr-cas-system til en gærværtscelle
BR112017016821A2 (pt) 2015-02-06 2018-04-03 Cargill Inc polipeptídeo, ácido nucleico, vetor, célula hospedeira, meio de fermentação, uso de polipeptídeo, composição de ração e método de fermentação
WO2016131818A1 (en) 2015-02-16 2016-08-25 Dsm Ip Assets B.V. Process for producing itaconic acid under anaerobic conditions
US10604743B2 (en) 2015-03-16 2020-03-31 Dsm Ip Assets B.V. UDP-glycosyltransferases
CA2979957A1 (en) 2015-03-23 2016-09-29 Dsm Ip Assets B.V. Udp-glycosyltransferases from solanum lycopersicum
US10344288B2 (en) 2015-03-27 2019-07-09 Cargill, Incorporated Glucoamylase-modified yeast strains and methods for bioproduct production
CA2980090A1 (en) 2015-04-03 2016-10-06 Dsm Ip Assets B.V. Steviol glycosides
CN107532141A (zh) 2015-04-21 2018-01-02 帝斯曼知识产权资产管理有限公司 香叶基香叶基焦磷酸合酶
CN107636144B (zh) 2015-05-22 2021-02-19 帝斯曼知识产权资产管理有限公司 消耗乙酸盐/酯的酵母细胞
MX2017015126A (es) 2015-06-02 2018-03-28 Dsm Ip Assets Bv Uso de proteina estructurante del hielo.
CN107820394A (zh) 2015-07-10 2018-03-20 帝斯曼知识产权资产管理有限公司 甜菊醇糖苷组合物
US10844363B2 (en) 2015-08-05 2020-11-24 Cargill, Incorporated Xylose isomerase-modified yeast strains and methods for bioproduct production
CN107922913B (zh) 2015-08-13 2022-04-05 帝斯曼知识产权资产管理有限公司 甜菊醇糖苷转运
MX2018003482A (es) 2015-09-21 2018-09-06 Purac Biochem Bv Produccion fungica de fdca.
WO2017050652A1 (en) 2015-09-25 2017-03-30 Dsm Ip Assets B.V. Asparaginase
CN108138152B (zh) 2015-10-05 2023-01-06 帝斯曼知识产权资产管理有限公司 贝壳杉烯酸羟化酶
CN108603179B (zh) * 2015-10-06 2022-02-08 帝斯曼知识产权资产管理有限公司 发酵产物生产增加的真核细胞
CA3004176A1 (en) 2015-11-24 2017-06-01 Cargill, Incorporated Genetically modified yeasts and fermentation processes using genetically modified yeasts
WO2017093450A1 (en) 2015-12-02 2017-06-08 Basf Se Method of producing proteins in filamentous fungi with decreased clr2 activity
US9988624B2 (en) 2015-12-07 2018-06-05 Zymergen Inc. Microbial strain improvement by a HTP genomic engineering platform
WO2017100376A2 (en) 2015-12-07 2017-06-15 Zymergen, Inc. Promoters from corynebacterium glutamicum
US11208649B2 (en) 2015-12-07 2021-12-28 Zymergen Inc. HTP genomic engineering platform
WO2017100377A1 (en) 2015-12-07 2017-06-15 Zymergen, Inc. Microbial strain improvement by a htp genomic engineering platform
WO2017115323A2 (en) 2015-12-30 2017-07-06 Dsm Ip Assets B.V. Partial enzymatic hydrolysis of triacylglycerols
KR20180098386A (ko) 2015-12-30 2018-09-03 디에스엠 아이피 어셋츠 비.브이. 트라이아실글리세롤의 부분 효소적 가수 분해
WO2017167847A1 (en) 2016-03-31 2017-10-05 Dsm Ip Assets B.V. Production of milk with low lactose content
EP3435771A1 (en) 2016-03-31 2019-02-06 DSM IP Assets B.V. Enzyme composition and preparation of a dairy product with improved properties
WO2017167849A1 (en) 2016-03-31 2017-10-05 Dsm Ip Assets B.V. Enzyme composition and preparation of a dairy product with improved properties
WO2017216136A1 (en) 2016-06-14 2017-12-21 Dsm Ip Assets B.V. Recombinant yeast cell
KR102345899B1 (ko) 2016-06-30 2021-12-31 지머젠 인코포레이티드 박테리아 헤모글로빈 라이브러리를 생성하는 방법 및 이의 용도
KR102345898B1 (ko) 2016-06-30 2022-01-03 지머젠 인코포레이티드 글루코오스 투과 효소 라이브러리를 생성하는 방법 및 이의 용도
CN109689864B (zh) 2016-07-13 2023-04-04 帝斯曼知识产权资产管理有限公司 苹果酸脱氢酶
WO2018019948A1 (en) 2016-07-29 2018-02-01 Dsm Ip Assets B.V. Polypeptides having cellulolytic enhancing activity and uses thereof
CN109661403A (zh) 2016-08-05 2019-04-19 嘉吉公司 前导序列修饰的葡糖淀粉酶多肽和具有增强的生物产物产生的工程化的酵母菌株
CA3033243A1 (en) 2016-08-09 2018-02-15 Dsm Ip Assets B.V. Crystallization of steviol glycosides
US11878992B2 (en) 2016-08-09 2024-01-23 Dsm Ip Assets B.V. Crystallization of steviol glycosides
US11066681B2 (en) 2016-08-26 2021-07-20 Lesaffre Et Compagnie Production of itaconic acid
WO2018073107A1 (en) 2016-10-19 2018-04-26 Dsm Ip Assets B.V. Eukaryotic cell comprising xylose isomerase
JP2019532655A (ja) 2016-10-27 2019-11-14 ディーエスエム アイピー アセッツ ビー.ブイ.Dsm Ip Assets B.V. ゲラニルゲラニルピロリン酸シンターゼ
CN110072995B (zh) 2016-12-08 2024-05-10 帝斯曼知识产权资产管理有限公司 贝壳杉烯酸羟化酶
WO2018114938A1 (en) 2016-12-21 2018-06-28 Dsm Ip Assets B.V. Lipolytic enzyme variants
WO2018114912A1 (en) 2016-12-21 2018-06-28 Dsm Ip Assets B.V. Lipolytic enzyme variants
MX2019007375A (es) 2016-12-21 2019-09-18 Dsm Ip Assets Bv Variante de enzima lipolitica.
US10918113B2 (en) 2016-12-21 2021-02-16 Dsm Ip Assets B.V. Lipolytic enzyme variants
WO2018114995A1 (en) 2016-12-22 2018-06-28 Dsm Ip Assets B.V. Fermentation process for producing steviol glycosides
EP3562945A4 (en) * 2016-12-30 2020-08-05 Zymergen, Inc. PROCESS FOR CONSTRUCTING FUNGAL PRODUCTION STRAINS USING AUTOMATED STEPS FOR GENETIC MANIPULATION AND STRAIN PURIFICATION
EP3596199A1 (en) 2017-03-13 2020-01-22 DSM IP Assets B.V. Zinc binuclear cluster transcriptional regulator-deficient strain
EP3378931A1 (en) 2017-03-21 2018-09-26 Purac Biochem B.V. Fdca-decarboxylating monooxygenase-deficient host cells for producing fdca
KR20200026878A (ko) 2017-06-06 2020-03-11 지머젠 인코포레이티드 균류 균주를 개량하기 위한 htp 게놈 공학 플랫폼
US20200102554A1 (en) 2017-06-06 2020-04-02 Zymergen Inc. High throughput transposon mutagenesis
WO2018228836A1 (en) 2017-06-13 2018-12-20 Dsm Ip Assets B.V. Recombinant yeast cell
WO2019002264A1 (en) 2017-06-27 2019-01-03 Dsm Ip Assets B.V. UDP-glycosyltransferase
WO2019063544A1 (en) 2017-09-26 2019-04-04 Dsm Ip Assets B.V. ACETIC ACID CONSUMER STRAIN
EP3533878A1 (en) 2018-02-28 2019-09-04 Dutch DNA Biotech B.V. Process for producing citramalic acid employing aspergillus
BR112020022516A2 (pt) 2018-05-07 2021-02-09 Dsm Ip Assets B.V. processo para degomagem enzimática de óleo
JP2021526799A (ja) 2018-06-06 2021-10-11 ザイマージェン インコーポレイテッド 発酵および産生中の真菌の形態を制御するためのシグナル伝達に関与する遺伝子の操作
CN112292037B (zh) 2018-06-19 2024-03-22 帝斯曼知识产权资产管理有限公司 脂解酶变体
EP4055170A1 (en) 2019-11-04 2022-09-14 DSM IP Assets B.V. Low volume transfection
WO2021144342A1 (en) 2020-01-14 2021-07-22 The Protein Brewery B.V. Expression of ovalbumin and its natural variants
US11479779B2 (en) 2020-07-31 2022-10-25 Zymergen Inc. Systems and methods for high-throughput automated strain generation for non-sporulating fungi
EP4232568A1 (en) 2020-10-22 2023-08-30 DSM IP Assets B.V. Microorganisms for diterpene production
EP4023757A1 (en) 2020-12-29 2022-07-06 The Protein Brewery B.V. Methods for generating selection marker-free transformants of heterokaryotic organisms
US20240294589A1 (en) 2021-06-24 2024-09-05 Fonterra Co-Operative Group Limited Recombinant proteins
CN118056011A (zh) 2021-07-12 2024-05-17 丹尼斯科美国公司 重组酵母细胞
MX2024000514A (es) 2021-07-12 2024-03-11 Danisco Us Inc Celula de levadura recombinante.
CN117940570A (zh) 2021-07-12 2024-04-26 丹尼斯科美国公司 重组酵母细胞
WO2023285297A1 (en) 2021-07-12 2023-01-19 Dsm Ip Assets B.V. Recombinant yeast cell
MX2024000509A (es) 2021-07-12 2024-03-15 Danisco Us Inc Celula de levadura recombinante.
WO2023285294A1 (en) 2021-07-12 2023-01-19 Dsm Ip Assets B.V. Recombinant yeast cell
WO2023079049A1 (en) 2021-11-04 2023-05-11 Dsm Ip Assets B.V. Variant polypeptide and recombinant yeast cell
EP4426848A1 (en) 2021-11-04 2024-09-11 Danisco Us Inc Process for the production of ethanol and recombinant yeast cell
CN118176296A (zh) 2021-11-04 2024-06-11 丹尼斯科美国公司 重组酵母细胞
EP4430174A1 (en) 2021-11-09 2024-09-18 Amgen Inc. Production of therapeutic proteins
WO2023222614A1 (en) 2022-05-16 2023-11-23 Dsm Ip Assets B.V. Lipolytic enzyme variants
WO2023242273A1 (en) 2022-06-14 2023-12-21 Newmilkbuzz B.V. Expression of milk caseins in filamentous fungi
WO2024133849A1 (en) 2022-12-22 2024-06-27 The Protein Brewery B.V. Ovalbumin fermentation
WO2024218244A1 (en) 2023-04-20 2024-10-24 Dsm Ip Assets B.V. Strains and methods for the production of mogrosides

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5422267A (en) * 1984-05-22 1995-06-06 Robert R. Yocum Industrial yeast comprising an integrated glucoamylase gene
ATE117020T1 (de) * 1985-08-29 1995-01-15 Genencor Int Expression von heterologen polypeptiden in filamentösen pilzen, verfahren zu deren herstellung und vektoren zu deren herstellung.
US5298405A (en) * 1986-04-30 1994-03-29 Alko Limited Enzyme preparations with recombinantly-altered cellulose profiles and methods for their production
US5079145A (en) * 1988-10-21 1992-01-07 Synergen Associates, Inc. Process for preparing microorganisms used for making phenyl acetyl carlinol (pac)
GB8904762D0 (en) * 1989-03-02 1989-04-12 Glaxo Group Ltd Biological process
US5695976A (en) * 1989-12-18 1997-12-09 Novo Nordisk A/S Stable integration of DNA in bacterial genomes
US5498830A (en) * 1990-06-18 1996-03-12 Monsanto Company Decreased oil content in plant seeds
US5824513A (en) * 1991-01-17 1998-10-20 Abbott Laboratories Recombinant DNA method for producing erythromycin analogs
EP0498137A1 (en) * 1991-02-06 1992-08-12 Novo Nordisk A/S Novel expression systems
WO1993001283A1 (en) * 1991-07-08 1993-01-21 The United States Of America As Represented By The Secretary Of Agriculture Selection-gene-free transgenic plants
EP0565172A1 (en) * 1992-04-10 1993-10-13 Quest International B.V. Cloning and expression of DNA encoding a ripening form of a polypeptide having sulfhydryl oxidase activity
CA2096289A1 (en) * 1992-05-15 1993-11-16 Wouter Musters Cloning and expression of dna encoding a ripening form of a polypeptide having rhamnogalacturonase activity
US6291205B1 (en) * 1992-06-12 2001-09-18 Merck & Co., Inc. Method of increasing production of disulfide bonded recombinant proteins by saccharomyces cerevisiae
US6110713A (en) * 1993-03-23 2000-08-29 Regents Of The University Of Minnesota Production of glutamic acid and lysine using auxotrophic mutants of Bacillus methanolicus

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CA2128589C (en) 2005-10-11
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CN1098743A (zh) 1995-02-15
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JP3833725B2 (ja) 2006-10-18
CA2128589A1 (en) 1995-01-24
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US6063614A (en) 2000-05-16
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IE20030875A1 (en) 2004-01-14
FI114481B (fi) 2004-10-29
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JPH07147971A (ja) 1995-06-13
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BR9402912A (pt) 1995-04-11
CN100347301C (zh) 2007-11-07
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