Classifications

• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
  • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
  • A61M5/178—Syringes
  • A61M5/31—Details
  • A61M5/3129—Syringe barrels
  • A61M5/3134—Syringe barrels characterised by constructional features of the distal end, i.e. end closest to the tip of the needle cannula
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
  • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
  • A61J1/14—Details; Accessories therefor
  • A61J1/1412—Containers with closing means, e.g. caps
• • B—PERFORMING OPERATIONS; TRANSPORTING
  • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
  • B29D—PRODUCING PARTICULAR ARTICLES FROM PLASTICS OR FROM SUBSTANCES IN A PLASTIC STATE
  • B29D99/00—Subject matter not provided for in other groups of this subclass
  • B29D99/0096—Producing closure members for containers, e.g. closure caps or stoppers
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
  • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
  • A61M5/178—Syringes
  • A61M5/31—Details
  • A61M2005/3103—Leak prevention means for distal end of syringes, i.e. syringe end for mounting a needle
  • A61M2005/3104—Caps for syringes without needle
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
  • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
  • A61M5/178—Syringes
  • A61M5/31—Details
  • A61M2005/3117—Means preventing contamination of the medicament compartment of a syringe
  • A61M2005/3118—Means preventing contamination of the medicament compartment of a syringe via the distal end of a syringe, i.e. syringe end for mounting a needle cannula
  • A61M2005/312—Means preventing contamination of the medicament compartment of a syringe via the distal end of a syringe, i.e. syringe end for mounting a needle cannula comprising sealing means, e.g. severable caps, to be removed prior to injection by, e.g. tearing or twisting
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
  • A61M2207/00—Methods of manufacture, assembly or production
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
  • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
  • A61M5/178—Syringes
  • A61M5/31—Details
  • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
  • A61M5/34—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub
  • A61M5/347—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub rotatable, e.g. bayonet or screw

Definitions

• the invention relates to a closure according to the preamble of claim 1, a closure according to the preamble of claim 3 and a method for producing a closure according to the preamble of claim 14.
• Closures of the type discussed here and methods for their production are known.
• Such a closure for a syringe or cartridge has a base body and a sealing member that is configured and / or arranged to sealingly engage an opening of a syringe or carpule when the closure is in its occluding position at the tip or carpule is arranged.
• Closures are also known which have a channel which passes through the base body and the sealing element and has a proximal and a distal end.
• a closure cap for closing the distal end of the channel is provided, as well as a safety cap which engages around the closure cap.
• the main body and the sealing element on the one hand and the closure cap and the safety cap on the other hand are formed in two pieces.
• the caps must therefore be preassembled before they can be placed on a syringe or carpule.
• the individual parts are typically quite small and can therefore be easily lost, in particular because they can not be handled as a unit.
• the production of the items requires separate production steps and a considerable logistical effort for storage and allocation.
• the object of the invention is therefore to provide a closure and a method for its production, wherein said disadvantages do not occur.
• a closure with the features of claim 1.
• This has, as already stated, a base body and a sealing element. It is characterized by the fact that it is integrally formed. This eliminates a pre-assembly, and the individual elements of the closure can not be lost. This in turn reduces the storage costs and the logistical effort.
• the closure is produced in the two-component injection molding process as a one-piece element.
• This allows in particular the injection molding of the base body of a first, relatively hard material, and the sealing element of a second, relatively soft or elastic material. It eliminates a production step, because the two elements do not need to be prepared in separate processes.
• a closure with the features of claim 3.
• This has, in addition to the main body and the sealing element on a channel which passes through the base body and the sealing element and has a proximal end and a distal end. It also includes a closure cap for closing the distal end of the channel, and also a safety cap which engages the closure cap.
• the closure is characterized in that either the base body and the sealing element or the closure cap and the safety cap or both partial pairs are integrally formed are.
• the main body can therefore be formed integrally with the sealing element.
• the closure cap and the safety cap are integrally formed.
• both the base body and the sealing element and the closure cap and the safety cap are each formed in one piece.
• the entire closure may preferably be formed in one piece.
• the base body and the sealing element and / or the closure cap and the safety cap are produced in the two-component injection molding process as one-piece elements. It is also possible to manufacture the whole closure in the two-component injection molding process as a one-piece element. This makes it possible, in particular, to produce the base body and / or the securing cap from a comparatively hard material, and the sealing element and / or the closure cap from a comparatively soft or elastic material.
• the base body and the securing cap are intended to give stability to the closure, while the sealing element and the closure cap are intended to seal the syringe or carpule or the distal end of the channel, for which they preferably have a certain elasticity, so that a tight contact is ensured.
• axial forces can be introduced from one element into the other element.
• the one element is entrained when the other element is removed from a syringe or carpule, because of the at least one projection axially and the walls enclosing these axial forces can be introduced from one to the other element.
• the object is also achieved by providing a method for producing a closure with the features of claim 14.
• the method is characterized by the following steps: First, a base body and / or a safety cap made of a first material is injected. Thereafter, a sealing element is sprayed onto the base body and / or a cap on the fuse cap.
• a second material is used. det.
• the first material is preferably comparatively hard, while the second material is comparatively soft or elastic.
• the first material is suitable for forming a support body, while the second material is suitable for forming a part which has sealing properties.
• Particularly preferred is a method in which the elements manufactured in the two injection molding steps are locked together during injection molding. At least one projection and at least one recess are formed on the elements, which engage with one another. In particular, a relative rotation of the elements can be avoided, which could possibly lead to leaks.
• Figure 1 shows a first embodiment of a closure in an isometric sectional view in a state before the closure is placed on a syringe or carpule
• Figure 2 is another isometric sectional view of the embodiment of Figure 1 in a state in which the closure is placed on a syringe or carpule, not shown
• Figure 3 shows another embodiment of a closure which is placed on a syringe or carpule.
• FIG. 1 shows an isometric sectional view with angled sectional plane of a first embodiment of a closure 1. This is intended for closing a syringe or carpule. It is also possible to close the closure 1 with a dual-chamber system.
• the closure has a main body 3 and a sealing element 5.
• the sealing element 5 is designed and / or arranged such that it sealingly engages an opening of a syringe or carpule, optionally also a dual-chamber system, when the closure is arranged in its closing position on the syringe or carpule or the dual-chamber system.
• the sealing element 5 is comparatively elastic, so that it is at least slightly compressible.
• the main body 3 is made comparatively hard. It serves as a support element for the sealing element 5. If the base body 3 is arranged with the sealing element 5 on a syringe or carpule in its Verschetzposition, it preferably engages in such a manner at the top or carpule that axial forces are introduced into the sealing element 5, which compress this.
• the sealing element 5 has a central projection 7, which can engage in the mouth of a tip or carpule.
• a radial bulge 9 extending in the circumferential direction, the outer diameter of which is preferably greater than the inner diameter of an orifice of the tip or carpule which is closed by the closure 1. Accordingly, the bead 9 is compressed when the shutter 1 is brought into its closing position. He then lies sealingly against an inner wall of the mouth. At least in one area, which - seen in the axial direction
• the base body 3 at least one, here several - seen in the circumferential direction
• a tip or carpule or a double-chamber system which is closed with the closure 1, has in its mouth region a flange on which an undercut or a groove is formed, in which in the Verschrudposition of the closure 1, the projections 15, 15 ' Because of the recesses 11, 11 ', the webs 13, 13', 13 "have a certain elasticity, so that they can pivot somewhat radially outward when the closure is put on, so that the closure 1 can be pushed over the flange. Reach the projections 15, 15 ', 15 "the undercut or groove, the webs spring 1 3, 13', 13" again radially inwardly, so that the projections 15, 15 ', 15 "engage in the undercut or groove and the Hold lock 1 on the flange.
• a retaining ring 17 is provided. This is in the state shown in Figure 1 by the closure 1 is not yet arranged in its Verschierposition, preferably via at least one Abr fabricat- web 19 connected to the main body 3. In this state, the securing ring 17 does not surround the webs 13, 13 ', 13 "After the closure has been brought into its closing position, the securing ring 17 is displaced in the direction of the projections 15, 15', 15". It has an edge 21 which, viewed in the radial direction, protrudes inwards. In this case, it preferably extends over the entire circumference of the securing ring 17 in the region of its inner surface 23. If the securing ring 17 is displaced downwards in FIG.
• the edge 21 engages behind a corresponding edge 25, which, viewed in the radial direction, projects outwardly As viewed in the circumferential direction, it extends along the webs 13, 13 ', 13 "In this way, the securing ring 17 is held in a locking position in which it can not be displaced relative to the base body 3, as viewed in the axial direction
• the webs 13, 13 ', 13 can no longer swing radially outward because they are encompassed by the retaining ring 17 and held in position.
• the closure 1 is held securely and firmly in its closing position in this way.
• the closure 1 may preferably be used in conjunction with dual-chamber systems in which substances in a distal chamber are lyophilized.
• the flange of such a dual-chamber system has a further groove into which the projections 15, 15 ', 15 "can engage, without the sealing element 5 sealingly abutting the mouth of the dual-chamber system
• a fluid path is then formed from the interior of the distal chamber via the recesses 11, 11 'into the environment of the dual-chamber system, through which solvent can evaporate until freeze-dried material remains behind
• the closure 1 can reach its lower end Locking position are brought, in which the projections 15, 15 ', 15 "engage in the undercut or first groove, which has already been explained.
• the dual-chamber system is then sealed by the closure 1.
• the closure 1 is formed in one piece. This means that the main body 3 and the sealing element 5 are not separate parts which are assembled to the closure 1. Instead, they form a preferably inseparable unit.
• the closure is produced in a two-component injection molding process. It can be made as a one-piece element.
• the main body preferably comprises a thermoplastic polymer, preferably polypropylene, more preferably it consists of this material.
• Polypropylene is a comparatively hard plastic, which is very well suited for the formation of the base body 3 as a support body for the sealing element 5.
• the sealing element 5 is made of TPE.
• TPE thermoplastic elastomer
• the sealing element 5 is made of TPE.
• TPE thermoplastic elastomer
• This is a comparatively elastic material, which is very well suited for the sealing properties of the sealing element 5.
• TPE is a so-called suitable material for the primary contact, which may come into contact with medicinal agents. For this reason, a surface which can come into direct contact with an active ingredient can easily comprise TPE or consist of TPE.
• the closure 1 is preferably designed such that only those elements which comprise TPE, preferably made of TPE, come into contact with an active substance, which in a chamber facing the closure 1 is a syringe or carpule or optionally in the distal chamber a dual-chamber system is arranged.
• the securing ring 17 is preferably produced together with the basic body 3 and particularly preferably from the same material as this. In a two-component injection molding process, therefore, the base body 3, the securing ring 17 and preferably also the tear-off webs 19 are produced in the same injection-molding step. In that regard, the retaining ring 17 is then part of the main body.
• the interconnected in the two-component injection molding process elements preferably have - seen in the radial direction - at least one projection and at least one recess, which engage in quasi latching.
• the two interconnected elements namely the base body 3 and the sealing element 5 - seen in the circumferential direction - a plurality of radial projections and recesses.
• three projections 27, 27 ', 27 are represented by the base body 3. These engage in corresponding recesses of the sealing element 5, which are not provided with a reference numeral here between the projections 27, 27', 27".
• recesses of the base body 3 are provided, which are engaged by projections 29, 29 ', 29 "of the sealing element 5.
• the base body 3 and the sealing element 5 are quasi locked together, in particular a relative rotation between the two Prevents elements that would otherwise possibly lead to a leak in the contact region of the sealing element 5 to the carpule or syringe and / or in the contact region of the sealing element 5 to the main body 3.
• At least one radial projection 31 is also provided on the main body 3, which - viewed in the axial direction - is encompassed on both sides by walls 33, 33 'of a radial recess of the sealing element 5.
• the projection 31 engages in the corresponding recess.
• a radial projection of the sealing element 5 -as seen in the axial direction - is encompassed on both sides by walls of a radial recess of the base body 3, whereby at then the projection of the sealing element 5 engages in the recess of the base body 3.
• one of the elements joined together by injection molding preferably has at least one radial projection which, viewed in the axial direction, is encompassed on both sides by walls of at least one radial recess of the other element, wherein the at least one projection engages in the at least one recess.
• FIG. 2 shows a view of the exemplary embodiment of a closure 1 according to FIG. 1 in the closing position.
• the same and functionally identical elements are provided with the same reference numerals, so that reference is made to the preceding description.
• the locking ring 17 is displaced here in its lower position. In this case, the edge 21 engages behind the edge 25, so that a displacement of the securing ring 17 is prevented back to its upper position.
• the locking ring 17 prevents radial pivoting of the webs 13, 13 ', 13 ", so that the projections 15, 5', 5" securely engage in the undercut or groove on the flange of the syringe or carpule.
• the closure 1 is securely held in its closed position in this way.
• the closure 1 destructive to remove from the syringe or carpule, or to relocate it from its Verschparposition out.
• the sealing element 5 is designed here as a septum, which is preferably pierceable by a cannula.
• the illustrated conclusion 1 is therefore particularly suitable for closing carpules. These are preferably used in pens and autoinjectors.
• FIG. 3 shows a further embodiment of a closure 1.
• the same and functionally identical elements are provided with the same reference numerals, so that reference is made to the preceding description.
• the embodiment shown here is preferably suitable for use with syringes or dual-chamber systems.
• the closure 1 has a channel 35 which passes through the base body 3 and the sealing element 5. In this case, it has a proximal end 37 and a distal end 39.
• the closure also includes a closure cap 41 which closes the distal end 39.
• a safety cap 43 is provided which engages around the cap 41. It is connected via at least one Abr composedsteg 45 with the retaining ring 17.
• This has in the embodiment shown in Figure 3 has a slightly different geometry than in the embodiment according to Figures 1 and 2, but fulfills the same function.
• FIG. 3 also shows the distal end of a syringe 47.
• an opening region 49 and an undercut or groove 51 are shown.
• the projections of the base body 3, of which projections 15, 15 "are shown engage in the undercut or groove 51 and thus hold the closure
• the locking ring 17 prevents a radial pivoting of the webs, of which the webs 13, 13 "are shown here, so that the closure 1 is securely held in its closing position.
• the base body 3 has a projection 53 for coupling to a delivery element for an active substance, for example a cannula or syringe needle.
• the projection 53 is cone-shaped. It is particularly preferably designed as a Luer cone.
• a Luer thread 55 is also provided on the base body 3, which surrounds the projection 53 and in a conventional manner the coupling of the base body with a discharge element is used.
• the closure cap 41 preferably bears sealingly against the attachment 53 with a wall region 57.
• the safety cap 43 and the cap 41 are formed as a one-piece element. These elements are particularly preferably produced in a two-component injection molding process as a one-piece element.
• the base body 3 and the sealing element 5 are formed as a one-piece element, particularly preferably produced in the two-component injection molding process as a one-piece element. It is also possible for the closure 1 to be designed as a whole in one piece, preferably in the two-component injection molding process, as a one-piece element.
• At least one projection and at least one recess are preferably provided, which engage in one another in a quasi latching manner.
• Particularly preferred are - seen in the circumferential direction - provided a plurality of radial projections and recesses.
• an annular projection 59 extending in the circumferential direction or at least two projections of the securing cap 43 extending in opposite directions engages in at least one annular recess or at least two opposite recesses of the closure cap 41.
• a plurality of projections and recesses be provided at an angular distance from each other. It is also possible for the projections on the closure cap 41 and the recesses to be correspondingly formed on the securing cap 43.
• the projection 59 engages in the corresponding recess. In this way, axial forces can be introduced, for example, from the securing cap 43 into the closure cap 41.
• the closure cap 41 is simultaneously taken along in this way. It is therefore removed simultaneously and together with the safety cap 43. This is particularly favorable, because such an additional step for activating the syringe 47 can be omitted.
• the base body 3 preferably comprises a thermoplastic polymer, preferably polypropylene, or is particularly preferably composed of this.
• the safety cap 43 preferably includes a thermoplastic propylene, preferably polypropylene or preferably consists of this.
• the sealing element 5 preferably comprises or preferably consists of TPE.
• the closure cap 41 preferably comprises TPE or consists particularly preferably of this.
• the closure cap 41 is preferably made of a comparatively soft or elastic material, so that they sealingly abut the wall region 57 on the projection 53 and so can close the distal end 39 of the channel 35.
• a central projection 63 is provided on the closure cap 41, which on the one hand sealingly bears against the distal end 39 and on the other projects into the channel 35 at least in some areas.
• the sealing element 5 protrudes into the channel 35, but does not reach through it completely.
• the projection 63 extends at least as far into the channel 35, that it bears sealingly against the sealing element 5.
• both the sealing element 5 and the closure cap 41 comprise material suitable for the primary contact or particularly preferably consist of such.
• the sealing contact of the projection 63 with the sealing element 5 reliably prevents a substance arranged in the syringe 47 from coming into contact with the base body 3. This can then comprise a material which is not suitable for the primary contact.
• the sealing element 5 passes through the channel 35 in the main body 3 completely.
• the sealing element 5 surrounds the projection 53 completely.
• the projection 63 in the illustrated embodiment game be comparatively short, because it rests close to the abutment portion 67. This also ensures that no substance present in the syringe 47 can come into contact with the material of the base body 3, because the sealing element 5 completely surrounds the channel 35 and in particular the projection 53 and forms the contact region 67.
• a sealing element 5 can be sprayed onto the base body without further ado, which completely passes through the channel 35 and in particular the projection 53, wherein it particularly preferably forms a contact region 67.
• the base body 3 and the sealing element 5 are particularly preferably designed as a one-piece element and are preferably produced in a two-component injection molding process.
• the closure cap 41 and the securing cap 43 are formed as an integral element and are preferably produced in a two-component injection molding process.
• the cap 41 is then advantageously taken when removing the fuse cap 43.
• the base body 3 and / or the securing cap 43 comprises polypropylene, or consists / consist of this.
• Polypropylene is a relatively hard material which is not suitable for primary contact.
• the sealing element 5 and / or the closure cap 41 preferably comprises / comprises / consists of TPE.
• TPE is a relatively elastic material suitable for primary contact.
• the relatively elastic elements that is to say in particular the sealing element 5 and / or the closure cap 41, may comprise or consist of TPE-V (crosslinked thermoplastic elastomer).
• the method for producing the closure 1 in a two-component injection molding process preferably comprises the following steps:
• the main body 3 is injected from a first material.
• the securing cap 43 is preferably sprayed from the same material.
• the base body 3 to which the securing cap 43 is optionally connected, the base body 3, the securing ring 17 and optionally the securing cap 43 are injected together from the first material. It is also possible that these process steps fall apart.
• the sealing element 5 is pointed to the base body 3.
• a second material is used.
• the closure cap 41 and the securing cap 43 are provided in the closure 1 - the closure cap 41 is sprayed onto the securing cap 43. Again, a second material is used.
• the base body 3 and the sealing element 5 are injected in the same tool.
• the safety cap 43 and the closure cap 41 are preferably sprayed in the same tool, particularly preferably in the same tool as the base body 3 and the sealing element 5.
• the base body 3 is preferably injection-molded from a material which comprises a thermoplastic polymer, in particular polypropylene, preferably consists of a thermoplastic polymer, in particular polypropylene.
• the sealing element 5 is preferably injection-molded from a material which comprises TPE, preferably consists of TPE. The same applies to the cap 41.
• the base body 3 and the sealing element 5 are locked together during injection molding.
• at least one projection or at least one recess are provided, which engage with each other latching.
• the closure cap 41 and the securing cap 43 are preferably latched together during injection molding in a corresponding manner.
• the safety cap 43 and the closure cap Pe 41 are produced as a one-piece element in a two-component injection molding process, and in particular the fact that the two elements are locked together, the overall height of the closure 1 can be reduced.
• the cap 41 and the safety cap 43 are formed in two pieces, the safety cap 43 not only the cap 41 but also overlap to protect the cap 41 from loss or unauthorized removal.
• the closure cap 41 is integrally formed with the safety cap 43, in particular with this latching, it is sufficient if the safety cap 43 surrounds the closure cap 41, as shown in FIG. The closure 1 can thus - seen in the longitudinal direction - have a shorter extension or smaller overall height.
• closures can be produced, in which an optimal connection of two elements, for example of base body 3 and sealing element 5 but also securing cap 43 and cap 41 is ensured.
• a pre-assembly is unnecessary, because the elements are provided in one piece. Small parts can not be lost.
• production, storage and logistical costs can be reduced with the help of the proposed closures and the proposed method.

Landscapes

• Health & Medical Sciences (AREA)
• Engineering & Computer Science (AREA)
• Life Sciences & Earth Sciences (AREA)
• Animal Behavior & Ethology (AREA)
• General Health & Medical Sciences (AREA)
• Public Health (AREA)
• Veterinary Medicine (AREA)
• Vascular Medicine (AREA)
• Anesthesiology (AREA)
• Biomedical Technology (AREA)
• Heart & Thoracic Surgery (AREA)
• Hematology (AREA)
• Pharmacology & Pharmacy (AREA)
• Mechanical Engineering (AREA)
• Infusion, Injection, And Reservoir Apparatuses (AREA)
• Closures For Containers (AREA)
• Medical Preparation Storing Or Oral Administration Devices (AREA)

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• 2012
  • 2012-02-23 JP JP2013555781A patent/JP2014508602A/ja active Pending
  • 2012-02-23 JP JP2013555780A patent/JP2014508601A/ja not_active Withdrawn
  • 2012-02-23 MX MX2013010047A patent/MX2013010047A/es not_active Application Discontinuation
  • 2012-02-23 EP EP12709011.6A patent/EP2680909A1/de not_active Withdrawn
  • 2012-02-23 US US14/002,507 patent/US20130338603A1/en not_active Abandoned
  • 2012-02-23 BR BR112013022563A patent/BR112013022563A2/pt not_active IP Right Cessation
  • 2012-02-23 US US14/002,535 patent/US20130338604A1/en not_active Abandoned
  • 2012-02-23 MX MX2013009991A patent/MX2013009991A/es not_active Application Discontinuation
  • 2012-02-23 CA CA2828919A patent/CA2828919A1/en not_active Abandoned
  • 2012-02-23 BR BR112013022565A patent/BR112013022565A2/pt not_active IP Right Cessation
  • 2012-02-23 RU RU2013144348/14A patent/RU2013144348A/ru not_active Application Discontinuation
  • 2012-02-23 WO PCT/EP2012/000786 patent/WO2012116791A1/de active Application Filing
  • 2012-02-23 WO PCT/EP2012/000785 patent/WO2012116790A1/de active Application Filing
  • 2012-02-23 CA CA2828904A patent/CA2828904A1/en not_active Abandoned
  • 2012-02-23 EP EP12706468.1A patent/EP2680908A1/de not_active Withdrawn
  • 2012-02-23 RU RU2013144355/14A patent/RU2013144355A/ru not_active Application Discontinuation

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