EG24180A - Farnesyl transferase inhibiting 1,2-annelated quinoline enantiomer - Google Patents

Farnesyl transferase inhibiting 1,2-annelated quinoline enantiomer

Info

Publication number: EG24180A
Authority: EG; Egypt
Prior art keywords: farnesyl transferase; transferase inhibiting; quinoline enantiomer; annelated quinoline; annelated
Prior art date: 2000-06-22

Application number

EG20010660A

Other languages

English (en)

Inventor

Marc G Venet

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-06-22

Filing date

2001-06-20

Publication date

2008-09-28

2001-06-20 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

2008-09-28 Application granted granted Critical

2008-09-28 Publication of EG24180A publication Critical patent/EG24180A/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Dermatology (AREA)
Pulmonology (AREA)
Immunology (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Hematology (AREA)
Obesity (AREA)
Ophthalmology & Optometry (AREA)
Surgery (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

EG20010660A 2000-06-22 2001-06-20 Farnesyl transferase inhibiting 1,2-annelated quinoline enantiomer EG24180A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP00202181		2000-06-22

Publications (1)

Publication Number	Publication Date
EG24180A true EG24180A (en)	2008-09-28

Family

ID=8171675

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EG20010660A EG24180A (en)	2000-06-22	2001-06-20	Farnesyl transferase inhibiting 1,2-annelated quinoline enantiomer

Country Status (34)

Country	Link
US (3)	US20030114471A1 (xx)
EP (1)	EP1296984B1 (xx)
JP (1)	JP4919575B2 (xx)
KR (2)	KR100846370B1 (xx)
CN (1)	CN1207296C (xx)
AR (1)	AR030704A1 (xx)
AT (1)	ATE294804T1 (xx)
AU (3)	AU2001263962B2 (xx)
BG (1)	BG65894B1 (xx)
BR (1)	BRPI0111743B8 (xx)
CA (1)	CA2410232C (xx)
CZ (1)	CZ295278B6 (xx)
DE (1)	DE60110592T2 (xx)
EA (1)	EA005065B1 (xx)
EE (1)	EE04966B1 (xx)
EG (1)	EG24180A (xx)
ES (1)	ES2241830T3 (xx)
HK (1)	HK1058363A1 (xx)
HR (1)	HRP20020989B1 (xx)
HU (1)	HU229095B1 (xx)
IL (2)	IL153560A0 (xx)
IS (1)	IS2596B (xx)
JO (1)	JO2361B1 (xx)
MX (1)	MXPA02012845A (xx)
MY (1)	MY127734A (xx)
NO (1)	NO324494B1 (xx)
NZ (1)	NZ522481A (xx)
PA (1)	PA8519501A1 (xx)
PL (1)	PL209521B1 (xx)
SA (1)	SA01220349B1 (xx)
SK (1)	SK285699B6 (xx)
UA (1)	UA73572C2 (xx)
WO (1)	WO2001098302A1 (xx)
ZA (1)	ZA200210305B (xx)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2003018135A1 (en)	2001-08-24	2003-03-06	Wyeth Holdings Corporation	Method of using 5-(arylsulfonyl)-,5-(arylsulfinyl), and 5-(arylsulfanyl)-thiazolidine-2,4-diones for inhibition of farnesyl-protein transferase
ATE336496T1 (de)	2002-04-15	2006-09-15	Janssen Pharmaceutica Nv	Farnesyl transferase hemmende tricyclische quinazolinederivate substitutiert mit kohlenstoff-gebundenen imidazolen oder triazolen
US20050003422A1 (en)	2003-07-01	2005-01-06	Mitch Reponi	Methods for assessing and treating cancer
US11311519B2 (en)	2014-05-01	2022-04-26	Eiger Biopharmaceuticals, Inc.	Treatment of hepatitis delta virus infection
US10076512B2 (en)	2014-05-01	2018-09-18	Eiger Biopharmaceuticals, Inc.	Treatment of hepatitis delta virus infection
WO2016090107A2 (en) *	2014-12-04	2016-06-09	Eiger Biopharmaceuticals, Inc.	Treatment of hepatitis delta virus infection
JP2018517673A (ja)	2015-04-21	2018-07-05	アイガー・バイオファーマシューティカルズ・インコーポレイテッドＥｉｇｅｒＢｉｏｐｈａｒｍａｃｅｕｔｉｃａｌｓ，Ｉｎｃ．	ロナファルニブおよびリトナビルを含む医薬組成物
LT3277842T (lt)	2015-08-17	2019-10-25	Kura Oncology Inc	Vėžio pacientų gydymo būdai farneziltransferazės inhibitoriais
AR110031A1 (es)	2016-11-03	2019-02-13	Kura Oncology Inc	Métodos de tratamiento de pacientes con cáncer con inhibidores de farnesiltransferasa

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1519765A (en) *	1974-09-05	1978-08-02	Ici Ltd	Pesticidal dihydrotetrazolo(1,5a) quinazolines compositions and processes
US4141979A (en) *	1976-12-23	1979-02-27	Pfizer Inc.	Tetrazolo[a]quinazol-5-ones antiallergy and antiulcer agents
GB9513577D0 (en) *	1995-07-04	1995-09-06	Brotherwood Rodney J	Improvements in passenger carrying vehicles
TW349948B (en) *	1995-10-31	1999-01-11	Janssen Pharmaceutica Nv	Farnesyl transferase inhibiting 2-quinolone derivatives
DK0865440T3 (da) *	1995-12-08	2002-07-22	Janssen Pharmaceutica Nv	Farnesylproteinfransferaseinhiberende (imidazol-5-yl)-2-quinolinonderivater
AU715658B2 (en)	1996-04-03	2000-02-10	Merck & Co., Inc.	Inhibitors of farnesyl-protein transferase
TW591030B (en) *	1997-03-10	2004-06-11	Janssen Pharmaceutica Nv	Farnesyl transferase inhibiting 1,8-annelated quinolinone derivatives substituted with N- or C-linked imidazoles
ES2289783T3 (es) *	1997-04-25	2008-02-01	Janssen Pharmaceutica N.V.	Quinazolinonas que inhiben la farnesiltransferasa.
WO1998055124A1 (en)	1997-06-02	1998-12-10	Janssen Pharmaceutica N.V.	(imidazol-5-yl)methyl-2-quinolinone derivatives as inhibitors of smooth muscle cell proliferation
CA2336624C (en) *	1998-07-06	2008-10-21	Janssen Pharmaceutica N.V.	Farnesyl protein transferase inhibitors with in vivo radiosensitizing properties
HU229358B1 (en)	1998-07-06	2013-11-28	Janssen Pharmaceutica Nv	Farnesyl protein transferase inhibitors for treating arthropathies
CA2341739C (en) *	1998-08-27	2005-07-12	Pfizer Products Inc.	Quinolin-2-one derivatives useful as anticancer agents
ES2259237T3 (es) *	1998-08-27	2006-09-16	Pfizer Products Inc.	Derivados de quinolin-2-ona alquinilsustituidos utiles como agentes anticancerosos.
TR200101961T2 (tr) *	1998-12-23	2001-12-21	Janssen Pharmaceutica N.V.	1,2-halkalı kinolin türevleri
US6462201B1 (en) *	1998-12-29	2002-10-08	Isp Investments Inc.	Process for the production of N-vinyl-2-pyrrolidone by vinylation
OA11833A (en) *	1999-02-11	2005-08-23	Pfizer Prod Inc	Heteroaryl-substituted quinolin-2-one derivatives useful as anticancer agents.
HN2000000266A (es)	2000-01-21	2001-05-21	Pfizer Prod Inc	Compuesto anticanceroso y metodo de separacion de enantiomeros util para sintetizar dicho compuesto.
EP1267848B1 (en)	2000-02-24	2007-10-17	Janssen Pharmaceutica N.V.	Dosing regimen comprising a farnesyl protein transferase inhibitor for the treatment of cancer
EP1322644A1 (en)	2000-09-25	2003-07-02	Janssen Pharmaceutica N.V.	Farnesyl transferase inhibiting 6-heterocyclylmethyl quinolinone derivatives
WO2002024686A2 (en)	2000-09-25	2002-03-28	Janssen Pharmaceutica N.V.	Farnesyl transferase inhibiting 6-heterocyclylmethyl quinoline and quinazoline derivatives

2001
- 2001-05-29 JO JO200183A patent/JO2361B1/en active
- 2001-06-13 NZ NZ522481A patent/NZ522481A/en not_active IP Right Cessation
- 2001-06-13 EA EA200300048A patent/EA005065B1/ru not_active IP Right Cessation
- 2001-06-13 CA CA002410232A patent/CA2410232C/en not_active Expired - Lifetime
- 2001-06-13 KR KR1020077026608A patent/KR100846370B1/ko active IP Right Grant
- 2001-06-13 PL PL358918A patent/PL209521B1/pl unknown
- 2001-06-13 JP JP2002504258A patent/JP4919575B2/ja not_active Expired - Lifetime
- 2001-06-13 AU AU2001263962A patent/AU2001263962B2/en not_active Expired
- 2001-06-13 CZ CZ2003114A patent/CZ295278B6/cs not_active IP Right Cessation
- 2001-06-13 ES ES01938263T patent/ES2241830T3/es not_active Expired - Lifetime
- 2001-06-13 MX MXPA02012845A patent/MXPA02012845A/es active IP Right Grant
- 2001-06-13 HU HU0300872A patent/HU229095B1/hu unknown
- 2001-06-13 AT AT01938263T patent/ATE294804T1/de active
- 2001-06-13 SK SK50-2003A patent/SK285699B6/sk not_active IP Right Cessation
- 2001-06-13 KR KR1020027014678A patent/KR100831940B1/ko active IP Right Grant
- 2001-06-13 US US10/312,301 patent/US20030114471A1/en not_active Abandoned
- 2001-06-13 EE EEP200200695A patent/EE04966B1/xx unknown
- 2001-06-13 UA UA20021210152A patent/UA73572C2/uk unknown
- 2001-06-13 WO PCT/EP2001/006747 patent/WO2001098302A1/en active IP Right Grant
- 2001-06-13 DE DE60110592T patent/DE60110592T2/de not_active Expired - Lifetime
- 2001-06-13 EP EP01938263A patent/EP1296984B1/en not_active Expired - Lifetime
- 2001-06-13 IL IL15356001A patent/IL153560A0/xx unknown
- 2001-06-13 CN CNB018113788A patent/CN1207296C/zh not_active Expired - Lifetime
- 2001-06-13 BR BRPI0111743-2 patent/BRPI0111743B8/pt not_active IP Right Cessation
- 2001-06-13 AU AU6396201A patent/AU6396201A/xx active Pending
- 2001-06-14 PA PA20018519501A patent/PA8519501A1/es unknown
- 2001-06-20 EG EG20010660A patent/EG24180A/xx active
- 2001-06-20 MY MYPI20012896A patent/MY127734A/en unknown
- 2001-06-21 AR ARP010102954A patent/AR030704A1/es not_active Application Discontinuation
- 2001-09-10 SA SA01220349A patent/SA01220349B1/ar unknown
2002
- 2002-10-25 IS IS6590A patent/IS2596B/is unknown
- 2002-11-25 BG BG107310A patent/BG65894B1/bg unknown
- 2002-12-12 HR HR20020989A patent/HRP20020989B1/xx not_active IP Right Cessation
- 2002-12-16 NO NO20026032A patent/NO324494B1/no not_active IP Right Cessation
- 2002-12-19 ZA ZA200210305A patent/ZA200210305B/en unknown
- 2002-12-19 IL IL153560A patent/IL153560A/en not_active IP Right Cessation
2004
- 2004-02-18 HK HK04101163A patent/HK1058363A1/xx not_active IP Right Cessation
2006
- 2006-09-20 AU AU2006220405A patent/AU2006220405B2/en not_active Expired
2007
- 2007-01-31 US US11/669,587 patent/US8329714B2/en active Active
- 2007-10-29 US US11/926,741 patent/US8318753B2/en active Active

Also Published As

Publication number	Publication date
AU2006220405B2 (en)	2009-05-21
CZ295278B6 (cs)	2005-06-15
US20030114471A1 (en)	2003-06-19
WO2001098302A1 (en)	2001-12-27
ATE294804T1 (de)	2005-05-15
DE60110592D1 (de)	2005-06-09
PA8519501A1 (es)	2002-08-29
AR030704A1 (es)	2003-09-03
PL358918A1 (en)	2004-08-23
AU6396201A (en)	2002-01-02
BG65894B1 (bg)	2010-04-30
US20080114009A1 (en)	2008-05-15
ZA200210305B (en)	2004-03-19
EE200200695A (et)	2004-06-15
JP4919575B2 (ja)	2012-04-18
IL153560A0 (en)	2003-07-06
ES2241830T3 (es)	2005-11-01
BR0111743A (pt)	2003-07-08
SA01220349B1 (ar)	2007-01-23
KR20070121847A (ko)	2007-12-27
CA2410232C (en)	2008-10-07
NO20026032L (no)	2002-12-16
JP2004501153A (ja)	2004-01-15
KR20030009463A (ko)	2003-01-29
EP1296984B1 (en)	2005-05-04
EA005065B1 (ru)	2004-10-28
KR100846370B1 (ko)	2008-07-15
NO324494B1 (no)	2007-10-29
HUP0300872A3 (en)	2004-11-29
KR100831940B1 (ko)	2008-05-23
BRPI0111743B1 (pt)	2019-03-26
AU2006220405A1 (en)	2006-10-12
CN1437601A (zh)	2003-08-20
HK1058363A1 (en)	2004-05-14
SK502003A3 (en)	2003-05-02
NZ522481A (en)	2004-09-24
PL209521B1 (pl)	2011-09-30
DE60110592T2 (de)	2006-01-19
IS2596B (is)	2010-03-15
SK285699B6 (sk)	2007-06-07
BG107310A (bg)	2003-07-31
UA73572C2 (en)	2005-08-15
CA2410232A1 (en)	2001-12-27
EA200300048A1 (ru)	2003-04-24
HUP0300872A2 (hu)	2003-07-28
NO20026032D0 (no)	2002-12-16
US8329714B2 (en)	2012-12-11
HRP20020989A2 (en)	2005-02-28
BRPI0111743B8 (pt)	2021-05-25
IL153560A (en)	2011-06-30
EP1296984A1 (en)	2003-04-02
EE04966B1 (et)	2008-02-15
AU2001263962B2 (en)	2006-07-20
CN1207296C (zh)	2005-06-22
IS6590A (is)	2002-10-25
HRP20020989B1 (en)	2011-05-31
JO2361B1 (en)	2006-12-12
MXPA02012845A (es)	2003-05-15
US8318753B2 (en)	2012-11-27
HU229095B1 (en)	2013-07-29
US20070259902A1 (en)	2007-11-08
CZ2003114A3 (cs)	2003-05-14
MY127734A (en)	2006-12-29

Publication	Publication Date	Title
RS99203A (xx)	2006-12-15	Pirolopirimidini kao inhibitori protein kinaza
GEP20053688B (en)	2005-12-12	Substituted-Triazolopyrimidines as Anticancer Agents
NZ517758A (en)	2004-06-25	Pyrazolopyrimidines useful as therapeutic agents
TW200505924A (en)	2005-02-16	Pyrazolo-quinazoline derivatives, process for their preparation and their use as kinase inhibitors
MY117961A (en)	2004-08-30	Inhibitors of farnesyl protein transferase
GEP20053479B (en)	2005-03-25	Pyrrolo[2,3-d]Pyrimidine Compounds, Pharmaceutical Composition Containing the Same and Use
AP2003002929A0 (en)	2003-12-31	Pyrrolopyrimidines as protein kinase inhibitors
IL173348A (en)	2015-11-30	Thienopyridine compounds, pharmaceuticals containing them and their use in the preparation of drugs
PL377821A1 (pl)	2006-02-20	2,4,6-tripodstawione pirymidyny jako inhibitory kinazy fosfatydyloinozytolu (PI) 3 i ich zastosowanie w leczeniu nowotworu
GEP20053511B (en)	2005-05-10	) β-Carboline Derivatives Useful as Inhibitors of Phosphodiesterase
RS20060004A (xx)	2008-06-05	DERIVATI PIROLO(3,4-c)PIRAZOLA AKTIVNI KAO INHIBITORI KINAZE
YU4903A (sh)	2006-03-03	N-/5-///5-alkil-2-oksazolil/metil/tio/-2-tiazolil/ karboksamidni inhibitori ciklin zavisnih kinaza
EG24180A (en)	2008-09-28	Farnesyl transferase inhibiting 1,2-annelated quinoline enantiomer
AU2972701A (en)	2001-08-14	3-aminopyrazole inhibitors of cyclin dependent kinases
DE50211929D1 (en)	2008-04-30	Pyrimidinderivate
WO2001030331A3 (en)	2002-01-24	Therapeutic compositions including protein kinase c inhibitors
WO2000001415A3 (en)	2000-04-13	Use of inhibitors of protein kinase c epsilon to treat pain
WO2001060458A3 (en)	2009-06-04	Inhibitors of prenyl-protein transferase
MXPA04005809A (es)	2004-09-13	Inhibidores de proteinas quinasas.
TW200503683A (en)	2005-02-01	Methods of using and compositions comprising immunomodulatory compounds for treatment, modification and management of pain
WO2002076930A3 (en)	2003-01-16	Substituted diarylureas as stimulators for fas-mediated apoptosis
TH59553B (th)	2003-11-24	1,2-แอนเนเลเทด ควิโนลีน อิแนนซิโอเมอร์ ซึ่งมีฤทธิ์ยับยั้งฟาร์เนซิลทรานส์เฟอเรส