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EE05073B1 - Retigabiin kasutamiseks neuropaatilise valu ravis - Google Patents

Retigabiin kasutamiseks neuropaatilise valu ravis

Info

Publication number
EE05073B1
EE05073B1 EEP200200145A EEP200200145A EE05073B1 EE 05073 B1 EE05073 B1 EE 05073B1 EE P200200145 A EEP200200145 A EE P200200145A EE P200200145 A EEP200200145 A EE P200200145A EE 05073 B1 EE05073 B1 EE 05073B1
Authority
EE
Estonia
Prior art keywords
retigabine
treatment
neuropathic pain
neuropathic
pain
Prior art date
Application number
EEP200200145A
Other languages
English (en)
Inventor
Rundfeldt Chris
Bartsch Reni
Rostock Angelika
Tober Christine
Dost Rita
Original Assignee
Viatris Gmbh & Co. Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Viatris Gmbh & Co. Kg filed Critical Viatris Gmbh & Co. Kg
Publication of EE200200145A publication Critical patent/EE200200145A/et
Publication of EE05073B1 publication Critical patent/EE05073B1/et

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Emergency Medicine (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EEP200200145A 1999-09-27 2000-09-22 Retigabiin kasutamiseks neuropaatilise valu ravis EE05073B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/406,135 US6117900A (en) 1999-09-27 1999-09-27 Use of retigabine for the treatment of neuropathic pain
PCT/EP2000/009284 WO2001022953A2 (de) 1999-09-27 2000-09-22 Verwendung von retigabin zur behandlung von neuropathischen schmerzen

Publications (2)

Publication Number Publication Date
EE200200145A EE200200145A (et) 2003-04-15
EE05073B1 true EE05073B1 (et) 2008-10-15

Family

ID=23606675

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200200145A EE05073B1 (et) 1999-09-27 2000-09-22 Retigabiin kasutamiseks neuropaatilise valu ravis

Country Status (35)

Country Link
US (1) US6117900A (et)
EP (1) EP1223927B1 (et)
JP (1) JP2003510273A (et)
KR (1) KR100730829B1 (et)
CN (2) CN100522155C (et)
AR (1) AR026163A1 (et)
AT (1) ATE288748T1 (et)
AU (1) AU777764B2 (et)
BG (1) BG65795B1 (et)
BR (1) BR0014293A (et)
CA (2) CA2659048A1 (et)
CZ (1) CZ295980B6 (et)
DE (1) DE50009504D1 (et)
DK (1) DK1223927T3 (et)
EE (1) EE05073B1 (et)
ES (1) ES2237461T3 (et)
HK (1) HK1052471A1 (et)
HR (1) HRP20020234A2 (et)
HU (1) HUP0202853A3 (et)
IL (3) IL148309A0 (et)
IS (1) IS6303A (et)
MX (1) MXPA02003179A (et)
NO (1) NO329744B1 (et)
NZ (1) NZ517616A (et)
PL (1) PL200847B1 (et)
PT (1) PT1223927E (et)
RS (1) RS50091B (et)
RU (1) RU2264813C2 (et)
SI (1) SI1223927T1 (et)
SK (1) SK286057B6 (et)
TR (1) TR200200706T2 (et)
TW (1) TWI257304B (et)
UA (1) UA72550C2 (et)
WO (1) WO2001022953A2 (et)
ZA (1) ZA200202449B (et)

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JP2003535833A (ja) * 2000-06-09 2003-12-02 ザ・リージェンツ・オブ・ザ・ユニバーシティ・オブ・カリフォルニア ナルブフィンとオピオイドアンタゴニストを使用した疼痛の処置法
US6348486B1 (en) 2000-10-17 2002-02-19 American Home Products Corporation Methods for modulating bladder function
US6589986B2 (en) 2000-12-20 2003-07-08 Wyeth Methods of treating anxiety disorders
WO2002061075A1 (fr) * 2001-02-01 2002-08-08 Takeda Chemical Industries, Ltd. Proteine de recepteur couple aux proteines g et adn correspondant
IL157313A0 (en) 2001-02-20 2004-02-19 Bristol Myers Squibb Co Modulators of kcnq potassium channels and uses thereof
AR033095A1 (es) * 2001-04-04 2003-12-03 Wyeth Corp Metodos para el tratamiento de motilidad gastrica hiperactiva
US20080039461A1 (en) * 2002-09-05 2008-02-14 Protter Andrew A Treatment of pain by inhibition of p38 map kinase
CA2497951A1 (en) * 2002-09-05 2004-03-18 Scios Inc. Treatment of pain by inhibition of p38 map kinase
US7632866B2 (en) 2002-10-21 2009-12-15 Ramot At Tel Aviv University Derivatives of N-phenylanthranilic acid and 2-benzimidazolone as potassium channel and/or neuron activity modulators
WO2004054511A2 (en) * 2002-12-13 2004-07-01 The Regents Of The University Of California Analgesic combination comprising nalbuphine
KR20050089862A (ko) * 2002-12-27 2005-09-08 하. 룬트벡 아크티에 셀스카브 중추신경계 장애의 치료에 유용한 1,2,4-트리아미노벤젠유도체
NZ540446A (en) * 2002-12-27 2008-03-28 Lundbeck & Co As H 1,2,4-Triaminobenzene derivatives useful for treating disorders of the central nervous system
MXPA05010174A (es) * 2003-04-25 2005-11-08 Lundbeck & Co As H Derivados de indol e indolina sustituidos.
US7799832B2 (en) * 2003-10-23 2010-09-21 Valeant Pharmaceuticals North America Combinations of retigabine and sodium channel inhibitors or sodium channel-influencing active compounds for treating pains
TWI349666B (en) 2004-03-12 2011-10-01 Lundbeck & Co As H Substituted morpholine and thiomorpholine derivatives
JP5237643B2 (ja) 2005-03-03 2013-07-17 ハー・ルンドベック・アクチエゼルスカベット 置換されたピリジン誘導体
US7960436B2 (en) * 2006-06-05 2011-06-14 Valeant Pharmaceuticals International Substituted arylamino-1,2,3,4-tetrahydro naphthalenes and-2,3-dihydro-1H-indenes as potassium channel modulators
US20080045534A1 (en) * 2006-08-18 2008-02-21 Valeant Pharmaceuticals North America Derivatives of 1,3-diamino benzene as potassium channel modulators
US8993593B2 (en) * 2006-08-23 2015-03-31 Valeant Pharmaceuticals International N-(4-(6-fluoro-3,4-dihydroisoquinolin-2(1H)-yl)-2,6-dimethylphenyl)-3,3-dimethylbutanamide as potassium channel modulators
SG174095A1 (en) * 2006-08-23 2011-09-29 Valeant Pharmaceuticals Int Derivatives of 4-(n-azacycloalkyl) anilides as potassium channel modulators
US8722929B2 (en) * 2006-10-10 2014-05-13 Valeant Pharmaceuticals International N-[2-amino-4-(phenylmethoxy)phenyl] amides and related compounds as potassium channel modulators
ATE538084T1 (de) * 2006-11-28 2012-01-15 Valeant Pharmaceuticals Int Bicyclische 1,4-retigabin-analoga als kaliumkanalhemmer
US8367684B2 (en) * 2007-06-13 2013-02-05 Valeant Pharmaceuticals International Derivatives of 4-(N-azacycloalkyl) anilides as potassium channel modulators
US8563566B2 (en) * 2007-08-01 2013-10-22 Valeant Pharmaceuticals International Naphthyridine derivatives as potassium channel modulators
US7786146B2 (en) * 2007-08-13 2010-08-31 Valeant Pharmaceuticals International Derivatives of 5-amino-4,6-disubstituted indole and 5-amino-4,6-disubstituted indoline as potassium channel modulators
CN101868443A (zh) 2007-09-20 2010-10-20 特拉维夫大学拉莫特有限公司 N-苯基邻氨基苯甲酸衍生物及其用途
US20100323016A1 (en) * 2008-07-18 2010-12-23 Biljana Nadjsombati Modified release formulation and methods of use
KR20110052641A (ko) * 2008-07-18 2011-05-18 베일언트 파마슈티컬스 인터내셔널 변형 방출형 제형 및 이의 이용 방법
US20100323015A1 (en) * 2008-07-18 2010-12-23 Biljana Nadjsombati Modified release formulation and methods of use
DE102009013612A1 (de) 2009-03-17 2010-09-23 Ratiopharm Gmbh Retigabin-Tabletten, bevorzugt mit modifizierter Freisetzung
DE102009013611A1 (de) 2009-03-17 2010-09-23 Ratiopharm Gmbh Festes Retigabin in nicht-kristalliner Form
DE102009013613A1 (de) 2009-03-17 2010-09-23 Ratiopharm Gmbh Trockenverarbeitung von Retigabin
IT1398282B1 (it) * 2009-07-30 2013-02-22 Difass S A Ora Farmapros S P A Composizione comprendente acido alfa-lipoico e carnosina per il trattamento della sindrome dell arto fantasma
US20110087650A1 (en) * 2009-10-06 2011-04-14 Johnson Controls Technology Company Creation and use of causal relationship models in building management systems and applications
TR201002473A2 (tr) * 2010-03-31 2011-09-21 Mustafa Nevzat �La� Sanay�� A.�. Herpes zoster hastalığının bır opiat reseptör antagonist kullanılarak tedavi yöntemi.
RU2446795C1 (ru) * 2011-03-31 2012-04-10 Федеральное государственное учреждение "Московский научно-исследовательский онкологический институт им. П.А. Герцена Министерства здравоохранения и социального развития Российской Федерации" ФГУ "МНИОИ им. П.А. Герцена "Минздравсоцразвития России" Способ предотвращения фантомного болевого синдрома после ампутации конечностей
CN102531966B (zh) * 2011-12-23 2013-07-24 山东创新药物研发有限公司 瑞替加滨的晶型d及其制备方法
US9345689B2 (en) * 2012-05-18 2016-05-24 Gruenenthal Gmbh Pharmaceutical composition comprising (1r,4r)-6′-fluoro-N, N-dimethyl-4-phenyl-4,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano[3,4,b]indol]-4-amine and an anticonvulsant
US20130310385A1 (en) 2012-05-18 2013-11-21 Gruenenthal Gmbh Pharmaceutical Composition Comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano[3,4,b]indol]-4-amine and Antidepressants
US9320725B2 (en) 2012-05-18 2016-04-26 Gruenenthal Gmbh Pharmaceutical composition comprising (1r,4r)-6′-fluoro-N,N-dimethyl-4-phenyl-4′9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano[3,4,b]indol]-4-amine and a gabapentinoid
CN103271899A (zh) * 2012-12-30 2013-09-04 北京阜康仁生物制药科技有限公司 瑞替加滨粉碎粒度在制剂中的应用
CN106176715A (zh) * 2016-06-29 2016-12-07 青岛云天生物技术有限公司 一种神经病理性疼痛治疗用药物组合物及其用途
CN105919990A (zh) * 2016-06-29 2016-09-07 青岛云天生物技术有限公司 用于预防和治疗神经病理性疼痛的药物组合物及其用途
US11369593B2 (en) 2017-07-14 2022-06-28 Texas Tech University System Functionalized pyridine carbamates with enhanced neuroprotective activity
KR20200063227A (ko) 2017-10-09 2020-06-04 라모트 앳 텔-아비브 유니버시티 리미티드 칼륨 이온 및 trpv1 채널의 조절제 및 이의 용도

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Also Published As

Publication number Publication date
IS6303A (is) 2002-03-18
IL187030A0 (en) 2008-02-09
WO2001022953A3 (de) 2002-05-23
PL200847B1 (pl) 2009-02-27
PL353393A1 (en) 2003-11-17
BG65795B1 (bg) 2009-12-31
JP2003510273A (ja) 2003-03-18
ZA200202449B (en) 2003-03-26
BG106450A (en) 2002-09-30
KR20020042691A (ko) 2002-06-05
HUP0202853A3 (en) 2003-10-28
NO20021418D0 (no) 2002-03-21
CZ2002989A3 (cs) 2002-08-14
SK286057B6 (sk) 2008-02-05
DK1223927T3 (da) 2005-04-11
CZ295980B6 (cs) 2005-12-14
CN100522155C (zh) 2009-08-05
TWI257304B (en) 2006-07-01
BR0014293A (pt) 2002-05-21
DE50009504D1 (de) 2005-03-17
UA72550C2 (en) 2005-03-15
IL148309A0 (en) 2002-09-12
EE200200145A (et) 2003-04-15
HK1052471A1 (zh) 2003-09-19
RU2002109240A (ru) 2004-01-10
RU2264813C2 (ru) 2005-11-27
AR026163A1 (es) 2003-01-29
SI1223927T1 (et) 2005-08-31
ES2237461T3 (es) 2005-08-01
ATE288748T1 (de) 2005-02-15
NZ517616A (en) 2002-12-20
IL187030A (en) 2011-06-30
US6117900A (en) 2000-09-12
CN1409632A (zh) 2003-04-09
PT1223927E (pt) 2005-06-30
CA2659048A1 (en) 2001-04-05
AU777764B2 (en) 2004-10-28
NO329744B1 (no) 2010-12-13
TR200200706T2 (tr) 2002-10-21
KR100730829B1 (ko) 2007-06-20
WO2001022953A2 (de) 2001-04-05
EP1223927A2 (de) 2002-07-24
EP1223927B1 (de) 2005-02-09
YU20302A (sh) 2005-03-15
AU7906100A (en) 2001-04-30
NO20021418L (no) 2002-03-21
HRP20020234A2 (en) 2003-06-30
CN101444498A (zh) 2009-06-03
IL148309A (en) 2007-12-03
SK2922002A3 (en) 2002-08-06
CA2384504C (en) 2009-05-26
CA2384504A1 (en) 2001-04-05
HUP0202853A2 (hu) 2002-12-28
MXPA02003179A (es) 2003-08-20
RS50091B (sr) 2009-01-22

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Legal Events

Date Code Title Description
GB1A Change in the ownership or in the address of the owner
HC1A Change of owner name
KB4A Valid patent at the end of a year

Effective date: 20081231

MM4A Lapsed by not paying the annual fees

Effective date: 20090922