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DK370489A - Rekombinant humant interleukin-2, dets fremstilling og anvendelse som laegemiddel - Google Patents

Rekombinant humant interleukin-2, dets fremstilling og anvendelse som laegemiddel Download PDF

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Publication number
DK370489A
DK370489A DK370489A DK370489A DK370489A DK 370489 A DK370489 A DK 370489A DK 370489 A DK370489 A DK 370489A DK 370489 A DK370489 A DK 370489A DK 370489 A DK370489 A DK 370489A
Authority
DK
Denmark
Prior art keywords
recombinant
humant
interleukin
medicine
manufacturing
Prior art date
Application number
DK370489A
Other languages
English (en)
Other versions
DK370489D0 (da
Inventor
Danielle Landbo
Philippe Riberon
Pierre Yves Abecassis
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of DK370489D0 publication Critical patent/DK370489D0/da
Publication of DK370489A publication Critical patent/DK370489A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C07K1/1133General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • C07K14/55IL-2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK370489A 1988-07-28 1989-07-27 Rekombinant humant interleukin-2, dets fremstilling og anvendelse som laegemiddel DK370489A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8810184A FR2635527B1 (fr) 1988-07-28 1988-07-28 Il2 humaine recombinante non glycosylee sous forme reduite, son procede d'obtention et son application comme medicament

Publications (2)

Publication Number Publication Date
DK370489D0 DK370489D0 (da) 1989-07-27
DK370489A true DK370489A (da) 1990-01-29

Family

ID=9368873

Family Applications (1)

Application Number Title Priority Date Filing Date
DK370489A DK370489A (da) 1988-07-28 1989-07-27 Rekombinant humant interleukin-2, dets fremstilling og anvendelse som laegemiddel

Country Status (21)

Country Link
US (2) US5874076A (da)
EP (1) EP0353150B1 (da)
JP (1) JP3016793B2 (da)
KR (1) KR0131070B1 (da)
CN (1) CN1036532C (da)
AT (1) ATE110783T1 (da)
AU (1) AU624625B2 (da)
DE (1) DE68917826T2 (da)
DK (1) DK370489A (da)
ES (1) ES2058573T3 (da)
FI (1) FI96209C (da)
FR (1) FR2635527B1 (da)
HU (1) HU207099B (da)
IE (1) IE64232B1 (da)
IL (1) IL90975A (da)
MX (1) MX16912A (da)
NZ (1) NZ230111A (da)
PT (1) PT91295B (da)
RU (1) RU2105011C1 (da)
UA (1) UA26846C2 (da)
ZA (1) ZA895419B (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2660863B1 (fr) * 1990-04-17 1994-01-21 Roussel Uclaf Utilisation d'un polypeptide ayant l'activite de l'interleukine 2 humaine pour preparer une composition pharmaceutique destinee au traitement de cancers primitifs de la plevre.
FR2668368B1 (fr) * 1990-10-30 1995-03-10 Roussel Uclaf Utilisation d'un polypeptide ayant l'activite de l'interleukine 2 humaine pour preparer une composition pharmaceutique destinee au traitement des tumeurs malignes epitheliales.
CA2073564A1 (fr) * 1990-11-23 1992-05-24 Pierre-Yves Abecassis Procede de preparation d'une proteine comportant au moins un pont disulfure intramoleculaire par oxydation, a un ph inferieur a 5,0, de la proteine recombinante reduite correspondante
FR2671728B1 (fr) * 1991-01-17 1995-01-20 Roussel Uclaf Utilisation d'un polypeptide ayant l'activite de l'interleukine 2 humaine pour la preparation de compositions pharmaceutiques destinees au traitement des pneumathorax.
FR2684878B1 (fr) * 1991-12-12 1994-02-11 Roussel Uclaf Composition pharmaceutique stabilisee d'il2 humaine recombinante non glycosylee sous forme reduite et son procede de preparation.
US6470207B1 (en) * 1999-03-23 2002-10-22 Surgical Navigation Technologies, Inc. Navigational guidance via computer-assisted fluoroscopic imaging
US20050203578A1 (en) * 2001-08-15 2005-09-15 Weiner Michael L. Process and apparatus for treating biological organisms
RU2372356C2 (ru) * 2003-08-07 2009-11-10 Займоджинетикс, Инк. Полипептид с антивирусной активностью, его получение и применение
CN111615396A (zh) 2017-11-21 2020-09-01 小利兰·斯坦福大学董事会 白介素-2的部分激动剂
CN115362168A (zh) 2020-01-14 2022-11-18 辛德凯因股份有限公司 偏向化il2突变蛋白方法和组合物

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1341562C (en) * 1982-03-31 2007-11-27 Tadatsugu Taniguchi Gene coded for interleukin-2 polypeptide, recombinant dna carrying the said gene, a living cell line possessing the recombinant dna, and method for producing interleukin-2 using the said cell
US5643566A (en) * 1982-09-23 1997-07-01 Cetus Corporation Formulation processes for lipophilic proteins
US4518584A (en) * 1983-04-15 1985-05-21 Cetus Corporation Human recombinant interleukin-2 muteins
JPS60115528A (ja) * 1983-11-28 1985-06-22 Takeda Chem Ind Ltd ヒトインタ―ロイキン―2蛋白質を含有する抗腫瘍用または免疫機能低下疾患治療用組成物
US4604377A (en) * 1984-03-28 1986-08-05 Cetus Corporation Pharmaceutical compositions of microbially produced interleukin-2
US4569790A (en) * 1984-03-28 1986-02-11 Cetus Corporation Process for recovering microbially produced interleukin-2 and purified recombinant interleukin-2 compositions
DE3583880D1 (de) * 1984-04-09 1991-10-02 Takeda Chemical Industries Ltd Stabile interleukin-2-zusammensetzung.
US4654830A (en) * 1984-11-27 1987-03-31 Monolithic Memories, Inc. Method and structure for disabling and replacing defective memory in a PROM
US4690915A (en) * 1985-08-08 1987-09-01 The United States Of America As Represented By The Department Of Health And Human Services Adoptive immunotherapy as a treatment modality in humans
JPH0829113B2 (ja) * 1986-11-11 1996-03-27 武田薬品工業株式会社 ヒトインタ−ロイキン−2の製造法

Also Published As

Publication number Publication date
JPH02209896A (ja) 1990-08-21
AU3902489A (en) 1990-02-01
FR2635527B1 (fr) 1992-06-12
IL90975A0 (en) 1990-02-09
RU2105011C1 (ru) 1998-02-20
KR900001854A (ko) 1990-02-27
US5874076A (en) 1999-02-23
DE68917826T2 (de) 1995-01-12
NZ230111A (en) 1992-04-28
FI893587A (fi) 1990-01-29
KR0131070B1 (ko) 1998-04-11
IE64232B1 (en) 1995-07-26
UA26846C2 (uk) 1999-12-29
CN1036532C (zh) 1997-11-26
ATE110783T1 (de) 1994-09-15
JP3016793B2 (ja) 2000-03-06
IE892443L (en) 1990-01-28
EP0353150A1 (fr) 1990-01-31
DE68917826D1 (de) 1994-10-06
ZA895419B (en) 1990-09-26
ES2058573T3 (es) 1994-11-01
HU207099B (en) 1993-03-01
FI96209B (fi) 1996-02-15
IL90975A (en) 1994-11-28
MX16912A (es) 1993-10-01
PT91295B (pt) 1995-03-01
PT91295A (pt) 1990-02-08
FI893587A0 (fi) 1989-07-27
AU624625B2 (en) 1992-06-18
HUT51647A (en) 1990-05-28
EP0353150B1 (fr) 1994-08-31
US5814314A (en) 1998-09-29
FI96209C (fi) 1996-05-27
CN1042377A (zh) 1990-05-23
FR2635527A1 (fr) 1990-02-23
DK370489D0 (da) 1989-07-27

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AHB Application shelved due to non-payment