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DE3886517D1 - Menschlicher Prourokinase ähnliches Polypeptid. - Google Patents

Menschlicher Prourokinase ähnliches Polypeptid.

Info

Publication number
DE3886517D1
DE3886517D1 DE88907361T DE3886517T DE3886517D1 DE 3886517 D1 DE3886517 D1 DE 3886517D1 DE 88907361 T DE88907361 T DE 88907361T DE 3886517 T DE3886517 T DE 3886517T DE 3886517 D1 DE3886517 D1 DE 3886517D1
Authority
DE
Germany
Prior art keywords
polypeptide
human prourokinase
prourokinase
human
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE88907361T
Other languages
English (en)
Other versions
DE3886517T2 (de
Inventor
Yoichi Kobayashi
Muneki Omori
Chikako Yamada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Central Glass Co Ltd
Hodogaya Chemical Co Ltd
Nippon Soda Co Ltd
Nissan Chemical Corp
Sagami Chemical Research Institute
Tosoh Corp
Original Assignee
Central Glass Co Ltd
Hodogaya Chemical Co Ltd
Nippon Soda Co Ltd
Nissan Chemical Corp
Sagami Chemical Research Institute
Tosoh Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Central Glass Co Ltd, Hodogaya Chemical Co Ltd, Nippon Soda Co Ltd, Nissan Chemical Corp, Sagami Chemical Research Institute, Tosoh Corp filed Critical Central Glass Co Ltd
Publication of DE3886517D1 publication Critical patent/DE3886517D1/de
Application granted granted Critical
Publication of DE3886517T2 publication Critical patent/DE3886517T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6462—Plasminogen activators u-Plasminogen activator (3.4.21.73), i.e. urokinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21073—Serine endopeptidases (3.4.21) u-Plasminogen activator (3.4.21.73), i.e. urokinase

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE88907361T 1987-08-19 1988-08-18 Menschlicher Prourokinase ähnliches Polypeptid. Expired - Fee Related DE3886517T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP20414987 1987-08-19
PCT/JP1988/000815 WO1989001513A1 (en) 1987-08-19 1988-08-18 Fast-acting prourokinase

Publications (2)

Publication Number Publication Date
DE3886517D1 true DE3886517D1 (de) 1994-02-03
DE3886517T2 DE3886517T2 (de) 1994-04-21

Family

ID=16485647

Family Applications (1)

Application Number Title Priority Date Filing Date
DE88907361T Expired - Fee Related DE3886517T2 (de) 1987-08-19 1988-08-18 Menschlicher Prourokinase ähnliches Polypeptid.

Country Status (5)

Country Link
US (1) US5188829A (de)
EP (1) EP0330700B1 (de)
DE (1) DE3886517T2 (de)
DK (1) DK187589A (de)
WO (1) WO1989001513A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2047702C (en) * 1989-03-06 2000-10-24 Joseph F. Sambrook Serpin resistant chymotrypsin superfamily proteases particularly pai-1 resistant t-pa, complementary inhibitor mutants; compositions; genes; expression
US5866413A (en) * 1989-03-06 1999-02-02 Board Of Regents Of The University Of Texas System Pai-1 mutants
GB8927722D0 (en) * 1989-12-07 1990-02-07 British Bio Technology Proteins and nucleic acids
EP0682700A4 (de) * 1993-02-05 1997-05-28 Vascular Lab Verwendung von urokinaseartigen plasminogenaktivatoren des inneren von plättchen für die langfristige inhibition der thrombose.
DE4323754C1 (de) * 1993-07-15 1994-12-01 Gruenenthal Gmbh Bifunktionelle Urokinasevarianten mit verbesserten fibrinolytischen Eigenschaften und thrombinhemmender Wirkung
DE4440892A1 (de) * 1994-11-17 1996-05-23 Gruenenthal Gmbh Proteine mit fibrinolytischen und gerinnungshemmenden Eigenschaften
GB9907553D0 (en) * 1999-04-01 1999-05-26 Cantab Pharma Res Purification of biological preparations
CN1311076C (zh) * 2003-04-16 2007-04-18 普罗特奥姆技术公司 生产重组尿激酶的方法
GB2446550B (en) * 2005-11-28 2010-12-08 Proteomtech Inc Methods for production of recombinant alpha1-antitrypsin
EP3019873A1 (de) 2013-07-12 2016-05-18 Emory University Diagnostischer assay zur vorhersage von kardiovaskulärem risiko

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2923074C2 (de) * 1979-06-07 1981-11-26 Feldmühle AG, 4000 Düsseldorf Schieber mit geräuschdämmenden Einbauten
US4370417A (en) * 1980-04-03 1983-01-25 Abbott Laboratories Recombinant deoxyribonucleic acid which codes for plasminogen activator
IL68366A (en) * 1982-04-15 1990-08-31 Genentech Inc Process for expressing a gene encoding a protein comprising the enzymatic portion of human urokinase in a microorganism or cell culture
JPS62143686A (ja) * 1985-01-25 1987-06-26 Sagami Chem Res Center 安定化されたヒト−プロウロキナ−ゼ
DE3680838D1 (de) * 1985-01-25 1991-09-19 Sagami Chem Res Stabilisierte menschliche prourokinase.
US5219569A (en) * 1985-04-22 1993-06-15 Genentech, Inc. Protease resistant urokinase

Also Published As

Publication number Publication date
DK187589D0 (da) 1989-04-18
EP0330700A1 (de) 1989-09-06
EP0330700A4 (de) 1990-01-08
DK187589A (da) 1989-04-18
WO1989001513A1 (en) 1989-02-23
EP0330700B1 (de) 1993-12-22
US5188829A (en) 1993-02-23
DE3886517T2 (de) 1994-04-21

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee