PT91295A - Processo para a preparacao de uma il/indice 2 humana recombinante nao glicosilada sob a forma reduzida - Google Patents
Processo para a preparacao de uma il/indice 2 humana recombinante nao glicosilada sob a forma reduzidaInfo
- Publication number
- PT91295A PT91295A PT91295A PT9129589A PT91295A PT 91295 A PT91295 A PT 91295A PT 91295 A PT91295 A PT 91295A PT 9129589 A PT9129589 A PT 9129589A PT 91295 A PT91295 A PT 91295A
- Authority
- PT
- Portugal
- Prior art keywords
- preparation
- human
- glycosylated
- recombinant human
- human recombinant
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
- C07K1/1133—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/55—IL-2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Analytical Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8810184A FR2635527B1 (fr) | 1988-07-28 | 1988-07-28 | Il2 humaine recombinante non glycosylee sous forme reduite, son procede d'obtention et son application comme medicament |
Publications (2)
Publication Number | Publication Date |
---|---|
PT91295A true PT91295A (pt) | 1990-02-08 |
PT91295B PT91295B (pt) | 1995-03-01 |
Family
ID=9368873
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT91295A PT91295B (pt) | 1988-07-28 | 1989-07-27 | Processo para a preparacao de uma il/indice 2 humana recombinante nao glicosilada sob a forma reduzida |
Country Status (21)
Country | Link |
---|---|
US (2) | US5874076A (pt) |
EP (1) | EP0353150B1 (pt) |
JP (1) | JP3016793B2 (pt) |
KR (1) | KR0131070B1 (pt) |
CN (1) | CN1036532C (pt) |
AT (1) | ATE110783T1 (pt) |
AU (1) | AU624625B2 (pt) |
DE (1) | DE68917826T2 (pt) |
DK (1) | DK370489A (pt) |
ES (1) | ES2058573T3 (pt) |
FI (1) | FI96209C (pt) |
FR (1) | FR2635527B1 (pt) |
HU (1) | HU207099B (pt) |
IE (1) | IE64232B1 (pt) |
IL (1) | IL90975A (pt) |
MX (1) | MX16912A (pt) |
NZ (1) | NZ230111A (pt) |
PT (1) | PT91295B (pt) |
RU (1) | RU2105011C1 (pt) |
UA (1) | UA26846C2 (pt) |
ZA (1) | ZA895419B (pt) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2660863B1 (fr) * | 1990-04-17 | 1994-01-21 | Roussel Uclaf | Utilisation d'un polypeptide ayant l'activite de l'interleukine 2 humaine pour preparer une composition pharmaceutique destinee au traitement de cancers primitifs de la plevre. |
FR2668368B1 (fr) * | 1990-10-30 | 1995-03-10 | Roussel Uclaf | Utilisation d'un polypeptide ayant l'activite de l'interleukine 2 humaine pour preparer une composition pharmaceutique destinee au traitement des tumeurs malignes epitheliales. |
JP3021040B2 (ja) * | 1990-11-23 | 2000-03-15 | ヘキスト・マリオン・ルセル | 少なくとも1個の分子内ジスルフィド結合を含有する蛋白質を相当する還元された組替え蛋白質を5.0以下のpHで酸化することによって製造する方法 |
FR2671728B1 (fr) * | 1991-01-17 | 1995-01-20 | Roussel Uclaf | Utilisation d'un polypeptide ayant l'activite de l'interleukine 2 humaine pour la preparation de compositions pharmaceutiques destinees au traitement des pneumathorax. |
FR2684878B1 (fr) * | 1991-12-12 | 1994-02-11 | Roussel Uclaf | Composition pharmaceutique stabilisee d'il2 humaine recombinante non glycosylee sous forme reduite et son procede de preparation. |
US6470207B1 (en) * | 1999-03-23 | 2002-10-22 | Surgical Navigation Technologies, Inc. | Navigational guidance via computer-assisted fluoroscopic imaging |
US20050203578A1 (en) * | 2001-08-15 | 2005-09-15 | Weiner Michael L. | Process and apparatus for treating biological organisms |
RU2372356C2 (ru) * | 2003-08-07 | 2009-11-10 | Займоджинетикс, Инк. | Полипептид с антивирусной активностью, его получение и применение |
WO2019104092A1 (en) | 2017-11-21 | 2019-05-31 | The Board Of Trustees Of The Leland Stanford Junior University | Partial agonists of interleukin-2 |
CN115362168A (zh) | 2020-01-14 | 2022-11-18 | 辛德凯因股份有限公司 | 偏向化il2突变蛋白方法和组合物 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1341562C (en) * | 1982-03-31 | 2007-11-27 | Tadatsugu Taniguchi | Gene coded for interleukin-2 polypeptide, recombinant dna carrying the said gene, a living cell line possessing the recombinant dna, and method for producing interleukin-2 using the said cell |
US5643566A (en) * | 1982-09-23 | 1997-07-01 | Cetus Corporation | Formulation processes for lipophilic proteins |
US4518584A (en) * | 1983-04-15 | 1985-05-21 | Cetus Corporation | Human recombinant interleukin-2 muteins |
JPS60115528A (ja) * | 1983-11-28 | 1985-06-22 | Takeda Chem Ind Ltd | ヒトインタ―ロイキン―2蛋白質を含有する抗腫瘍用または免疫機能低下疾患治療用組成物 |
US4604377A (en) * | 1984-03-28 | 1986-08-05 | Cetus Corporation | Pharmaceutical compositions of microbially produced interleukin-2 |
US4569790A (en) * | 1984-03-28 | 1986-02-11 | Cetus Corporation | Process for recovering microbially produced interleukin-2 and purified recombinant interleukin-2 compositions |
EP0158487B1 (en) * | 1984-04-09 | 1991-08-28 | Takeda Chemical Industries, Ltd. | Stable composition of interleukin-2 |
US4654830A (en) * | 1984-11-27 | 1987-03-31 | Monolithic Memories, Inc. | Method and structure for disabling and replacing defective memory in a PROM |
US4690915A (en) * | 1985-08-08 | 1987-09-01 | The United States Of America As Represented By The Department Of Health And Human Services | Adoptive immunotherapy as a treatment modality in humans |
JPH0829113B2 (ja) * | 1986-11-11 | 1996-03-27 | 武田薬品工業株式会社 | ヒトインタ−ロイキン−2の製造法 |
-
1988
- 1988-07-28 FR FR8810184A patent/FR2635527B1/fr not_active Expired - Fee Related
-
1989
- 1989-07-14 IL IL9097589A patent/IL90975A/en unknown
- 1989-07-17 ZA ZA895419A patent/ZA895419B/xx unknown
- 1989-07-25 MX MX1691289A patent/MX16912A/es unknown
- 1989-07-26 EP EP89402124A patent/EP0353150B1/fr not_active Expired - Lifetime
- 1989-07-26 ES ES89402124T patent/ES2058573T3/es not_active Expired - Lifetime
- 1989-07-26 AT AT89402124T patent/ATE110783T1/de not_active IP Right Cessation
- 1989-07-26 DE DE68917826T patent/DE68917826T2/de not_active Expired - Lifetime
- 1989-07-27 HU HU893827A patent/HU207099B/hu not_active IP Right Cessation
- 1989-07-27 DK DK370489A patent/DK370489A/da not_active Application Discontinuation
- 1989-07-27 NZ NZ230111A patent/NZ230111A/en unknown
- 1989-07-27 FI FI893587A patent/FI96209C/fi not_active IP Right Cessation
- 1989-07-27 UA UA5010517A patent/UA26846C2/uk unknown
- 1989-07-27 IE IE244389A patent/IE64232B1/en not_active IP Right Cessation
- 1989-07-27 JP JP1192769A patent/JP3016793B2/ja not_active Expired - Lifetime
- 1989-07-27 PT PT91295A patent/PT91295B/pt not_active IP Right Cessation
- 1989-07-28 AU AU39024/89A patent/AU624625B2/en not_active Ceased
- 1989-07-28 CN CN89106242A patent/CN1036532C/zh not_active Expired - Fee Related
- 1989-07-28 KR KR1019890010832A patent/KR0131070B1/ko not_active IP Right Cessation
-
1992
- 1992-01-08 RU SU5010517A patent/RU2105011C1/ru active
-
1995
- 1995-10-17 US US08/544,092 patent/US5874076A/en not_active Expired - Fee Related
-
1996
- 1996-02-12 US US08/601,434 patent/US5814314A/en not_active Expired - Fee Related
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
KR910003102A (ko) | 사람 에리트로포이에틴의 뮤테인 | |
DE3680251D1 (de) | Fluorpolymerzusammensetzungen, deren herstellung und verwendung. | |
ATE198754T1 (de) | Antikörper gegen saugetier-interleukin-4 und peptide verwendbar als antigenen für deren herstellung | |
NL300116I2 (nl) | Nieuwe osteoinductieve samenstellingen. | |
DE69208503D1 (de) | Mikroverkapseltes Sonnenschutzmittel, das Verfahren zur Herstellung, kosmetische und pharmazeutische Zubereitungen mit Mikrokapseln und Verwendung derselben | |
BR8703902A (pt) | Composicao bioativa,e processos de producao e de aplicacao de uma composicao bioativa | |
PT88971A (pt) | Processo para a preparacao de uma composicao util para o tratamento do cabelo | |
PT91295A (pt) | Processo para a preparacao de uma il/indice 2 humana recombinante nao glicosilada sob a forma reduzida | |
MX9200709A (es) | Activacion mejorada de proteinas recombinadas. activacion mejorada de proteinas recombinadas. | |
DE3689191D1 (de) | Gereinigtes protein mit angiogenischer wirkung und dessen herstellung. | |
BR8901808A (pt) | Composicao de polimero e processo para beneficiamento de minerio de sulfeto | |
DE68925366D1 (de) | Konjugierte polypeptide und verfahren zur herstellung und verwendung | |
ATE71658T1 (de) | Verfahren zur herstellung von humanlysozym. | |
DE3650715D1 (de) | Verwendung von menschlichem Interferon-Beta 2A für die Herstellung von Medikamenten | |
DE3382194D1 (de) | Polypeptidfraktionen die gegen malariaparasiten schuetzende antikoerper induzieren und dieselben enthaltende immunogene zusammensetzungen. | |
DE69106407D1 (de) | Verfahren zur Herstellung von rekombinantem menschlichem gamma-Interferon ohne Cystein und ohne Methionin am N-Terminal. | |
FR2622103B1 (fr) | Nouvelles compositions dermatologiques bronzantes insectifuges | |
ES2142840T3 (es) | Proteina que se une al interferon alfa/beta, su preparacion y las composiciones farmaceuticas que la contienen. | |
PT88915A (pt) | Processo para a preparacao a uma proteina recombinante rica em histidina do plasmodium falciparum | |
ATE95234T1 (de) | Verfahren zur herstellung von proteinen mit fviii aktivitaet und/oder fviii derivate. | |
ATE100823T1 (de) | Verfahren zur herstellung von glukagonhomologen und deren verwendung. | |
ATE86113T1 (de) | Verfahren und zusammensetzungen fuer die behandlung von infektionen bei saeugetieren durch verwendung von arzneimitteln mit einem gehalt an hymenopteragift, eiweissartigen oder polypeptidkomponenten hiervon, oder analogen solcher eiweissartigen oder polypeptidkomponenten. | |
ATE65270T1 (de) | Fluorpolymerzusammensetzungen, deren herstellung und verwendung. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG3A | Patent granted, date of granting |
Effective date: 19940817 |
|
PC3A | Transfer or assignment |
Free format text: 19991011 HOECHST MARION ROUSSEL FR |
|
PD3A | Change of proprietorship |
Owner name: ROUSSEL UCLAF Effective date: 19991011 |
|
TE3A | Change of address (patent) |
Owner name: ROUSSEL UCLAF Effective date: 19991011 |
|
MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 20010228 |