DK1341774T3 - Kondenserede heteroaromatiske glucokinase-aktivatorer - Google Patents

Kondenserede heteroaromatiske glucokinase-aktivatorer

Info

Publication number: DK1341774T3
Authority: DK; Denmark
Prior art keywords: glucokinase activators; condensed heteroaromatic; heteroaromatic glucokinase; condensed; activators
Prior art date: 2000-12-06

Application number

DK01999565T

Other languages

Danish (da)

English (en)

Inventor

Wendy Lea Corbett

Nancy-Ellen Haynes

Robert Francis Kester

Paige Erin Mahaney

Ramakanth Sarabu

Joseph Samuel Grimbsy

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-12-06

Filing date

2001-11-28

Publication date

2006-06-12

2001-11-28 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

2006-06-12 Application granted granted Critical

2006-06-12 Publication of DK1341774T3 publication Critical patent/DK1341774T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/30—Nitrogen atoms not forming part of a nitro radical
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D277/82—Nitrogen atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Diabetes (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Endocrinology (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Obesity (AREA)
Emergency Medicine (AREA)
Hematology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Quinoline Compounds (AREA)
Thiazole And Isothizaole Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Other In-Based Heterocyclic Compounds (AREA)

DK01999565T 2000-12-06 2001-11-28 Kondenserede heteroaromatiske glucokinase-aktivatorer DK1341774T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US25163700P	2000-12-06	2000-12-06

Publications (1)

Publication Number	Publication Date
DK1341774T3 true DK1341774T3 (da)	2006-06-12

Family

ID=22952803

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK01999565T DK1341774T3 (da)	2000-12-06	2001-11-28	Kondenserede heteroaromatiske glucokinase-aktivatorer

Country Status (21)

Country	Link
US (3)	US6545155B2 (zh)
EP (1)	EP1341774B1 (zh)
JP (1)	JP4109111B2 (zh)
KR (1)	KR100545431B1 (zh)
CN (1)	CN1226294C (zh)
AR (1)	AR031627A1 (zh)
AT (1)	ATE316965T1 (zh)
AU (2)	AU2002221902B2 (zh)
BR (1)	BR0115999A (zh)
CA (1)	CA2429642C (zh)
DE (1)	DE60117059T2 (zh)
DK (1)	DK1341774T3 (zh)
ES (1)	ES2256340T3 (zh)
GT (1)	GT200100243A (zh)
MX (1)	MXPA03005119A (zh)
PA (1)	PA8534301A1 (zh)
PE (1)	PE20020753A1 (zh)
PT (1)	PT1341774E (zh)
UY (1)	UY27055A1 (zh)
WO (1)	WO2002046173A1 (zh)
ZA (1)	ZA200303748B (zh)

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US6775812B2 (en) *	2002-07-17	2004-08-10	Hewlett-Packard Development Company, L.P.	Layout design process and system for providing bypass capacitance and compliant density in an integrated circuit
DK1549638T3 (da)	2002-10-03	2008-01-21	Hoffmann La Roche	Indol-3-carboxamider som glucokinase (GK) aktivatorer
CN1703408A (zh) *	2002-10-03	2005-11-30	诺瓦提斯公司	作为葡糖激酶激活剂、可用于治疗ⅱ型糖尿病的取代的(噻唑－2－基)酰胺或磺酰胺
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WO2005095418A1 (en) *	2004-04-02	2005-10-13	Novartis Ag	Sulfonamide-thiazolpyridine derivatives as glucokinase activators useful the treatment of type 2 diabetes
BRPI0510163A (pt) *	2004-04-21	2007-10-02	Prosidion Ltd	compostos de amidas tri(ciclo)-substituìdas
TW200600086A (en) *	2004-06-05	2006-01-01	Astrazeneca Ab	Chemical compound
CA2576407A1 (en)	2004-08-12	2006-02-16	Prosidion Limited	Substituted phenylacetamides and their use as glucokinase activators
GB0423044D0 (en) *	2004-10-16	2004-11-17	Astrazeneca Ab	Compounds
GB0423043D0 (en) *	2004-10-16	2004-11-17	Astrazeneca Ab	Compounds
WO2006040527A1 (en)	2004-10-16	2006-04-20	Astrazeneca Ab	Process for making phenoxy benzamide compounds
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DE102005012872A1 (de) *	2005-03-19	2006-09-28	Sanofi-Aventis Deutschland Gmbh	Substituierte, bizyklische 8-Pyrrolidino-benzimidazole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
US20110059941A1 (en) *	2005-05-24	2011-03-10	Peter William Rodney Caulkett	2-phenyl substituted imidazol [4,5b] pyridine/pyrazine and purine derivatives as glucokinase modulators
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2001
- 2001-11-28 EP EP01999565A patent/EP1341774B1/en not_active Expired - Lifetime
- 2001-11-28 DK DK01999565T patent/DK1341774T3/da active
- 2001-11-28 CN CNB018194494A patent/CN1226294C/zh not_active Expired - Fee Related
- 2001-11-28 JP JP2002547912A patent/JP4109111B2/ja not_active Expired - Fee Related
- 2001-11-28 AT AT01999565T patent/ATE316965T1/de not_active IP Right Cessation
- 2001-11-28 DE DE60117059T patent/DE60117059T2/de not_active Expired - Lifetime
- 2001-11-28 WO PCT/EP2001/013870 patent/WO2002046173A1/en active IP Right Grant
- 2001-11-28 ES ES01999565T patent/ES2256340T3/es not_active Expired - Lifetime
- 2001-11-28 PT PT01999565T patent/PT1341774E/pt unknown
- 2001-11-28 BR BR0115999-2A patent/BR0115999A/pt not_active IP Right Cessation
- 2001-11-28 CA CA002429642A patent/CA2429642C/en not_active Expired - Fee Related
- 2001-11-28 AU AU2002221902A patent/AU2002221902B2/en not_active Ceased
- 2001-11-28 KR KR1020037007517A patent/KR100545431B1/ko not_active IP Right Cessation
- 2001-11-28 AU AU2190202A patent/AU2190202A/xx active Pending
- 2001-12-04 AR ARP010105639A patent/AR031627A1/es unknown
- 2001-12-04 US US10/006,170 patent/US6545155B2/en not_active Expired - Fee Related
- 2001-12-04 PE PE2001001217A patent/PE20020753A1/es not_active Application Discontinuation
- 2001-12-04 US US10/006,168 patent/US6441184B1/en not_active Expired - Fee Related
- 2001-12-04 PA PA20018534301A patent/PA8534301A1/es unknown
- 2001-12-04 US US10/007,091 patent/US6448399B1/en not_active Expired - Fee Related
- 2001-12-05 GT GT200100243A patent/GT200100243A/es unknown
- 2001-12-05 UY UY27055A patent/UY27055A1/es not_active Application Discontinuation
2003
- 2003-05-14 ZA ZA200303748A patent/ZA200303748B/en unknown
- 2003-06-06 MX MXPA03005119A patent/MXPA03005119A/es active IP Right Grant

Also Published As

Publication number	Publication date
KR100545431B1 (ko)	2006-01-24
AU2190202A (en)	2002-06-18
KR20030068555A (ko)	2003-08-21
EP1341774B1 (en)	2006-02-01
MXPA03005119A (es)	2004-10-15
CN1226294C (zh)	2005-11-09
GT200100243A (es)	2002-06-04
US20020103241A1 (en)	2002-08-01
US6441184B1 (en)	2002-08-27
US20020103199A1 (en)	2002-08-01
EP1341774A1 (en)	2003-09-10
PT1341774E (pt)	2006-05-31
PE20020753A1 (es)	2002-08-27
US20020107396A1 (en)	2002-08-08
BR0115999A (pt)	2003-09-30
DE60117059T2 (de)	2006-10-26
CN1476438A (zh)	2004-02-18
JP2004517087A (ja)	2004-06-10
ZA200303748B (en)	2004-08-16
AR031627A1 (es)	2003-09-24
ATE316965T1 (de)	2006-02-15
CA2429642A1 (en)	2002-06-13
US6545155B2 (en)	2003-04-08
JP4109111B2 (ja)	2008-07-02
WO2002046173A1 (en)	2002-06-13
CA2429642C (en)	2007-11-20
AU2002221902B2 (en)	2006-11-23
UY27055A1 (es)	2002-07-31
ES2256340T3 (es)	2006-07-16
US6448399B1 (en)	2002-09-10
PA8534301A1 (es)	2002-08-26
DE60117059D1 (de)	2006-04-13

Publication	Publication Date	Title
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