Nothing Special   »   [go: up one dir, main page]

DK0668851T3 - Hidtil ukendt arylpropionsyrederivat, fremgangsmåde til fremstilling heraf og anvendelse heraf som analgetisk middel - Google Patents

Hidtil ukendt arylpropionsyrederivat, fremgangsmåde til fremstilling heraf og anvendelse heraf som analgetisk middel

Info

Publication number
DK0668851T3
DK0668851T3 DK93924604.7T DK93924604T DK0668851T3 DK 0668851 T3 DK0668851 T3 DK 0668851T3 DK 93924604 T DK93924604 T DK 93924604T DK 0668851 T3 DK0668851 T3 DK 0668851T3
Authority
DK
Denmark
Prior art keywords
analgesic
preparation
propionic acid
acid derivative
hitherto unknown
Prior art date
Application number
DK93924604.7T
Other languages
Danish (da)
English (en)
Inventor
Germano Carganico
Casellas David Mauleon
Perez M Luisa Garcia
Original Assignee
Menarini Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Menarini Lab filed Critical Menarini Lab
Application granted granted Critical
Publication of DK0668851T3 publication Critical patent/DK0668851T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
    • C07C215/06—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
    • C07C215/10—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with one amino group and at least two hydroxy groups bound to the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/84—Unsaturated compounds containing keto groups containing six membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DK93924604.7T 1992-11-10 1993-11-09 Hidtil ukendt arylpropionsyrederivat, fremgangsmåde til fremstilling heraf og anvendelse heraf som analgetisk middel DK0668851T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES09202260A ES2058024B1 (es) 1992-11-10 1992-11-10 Nuevo derivado arilpropionico, procedimiento de fabricacion del mismo y su utilizacion como analgesico.

Publications (1)

Publication Number Publication Date
DK0668851T3 true DK0668851T3 (da) 1997-12-22

Family

ID=8278730

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93924604.7T DK0668851T3 (da) 1992-11-10 1993-11-09 Hidtil ukendt arylpropionsyrederivat, fremgangsmåde til fremstilling heraf og anvendelse heraf som analgetisk middel

Country Status (27)

Country Link
US (1) US5554789A (es)
EP (1) EP0668851B1 (es)
JP (1) JP3778516B2 (es)
KR (1) KR100284838B1 (es)
AT (1) ATE153649T1 (es)
AU (1) AU674040B2 (es)
BG (1) BG61723B1 (es)
BR (1) BR9307408A (es)
CA (1) CA2149013C (es)
CZ (1) CZ286621B6 (es)
DE (2) DE69311130T2 (es)
DK (1) DK0668851T3 (es)
ES (2) ES2058024B1 (es)
FI (1) FI108637B (es)
GR (2) GR960300012T1 (es)
HK (1) HK1006306A1 (es)
HU (2) HU219975B (es)
MD (1) MD921G2 (es)
NO (2) NO304306B1 (es)
NZ (1) NZ257557A (es)
PL (1) PL175265B1 (es)
RO (1) RO118712B1 (es)
RU (1) RU2128160C1 (es)
SK (1) SK280550B6 (es)
UA (1) UA44233C2 (es)
UY (1) UY24179A1 (es)
WO (1) WO1994011332A1 (es)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2124196B1 (es) * 1997-06-04 1999-12-01 Menarini Lab Procedimiento para la fabricacion de una forma farmaceutica semisolida conteniendo dexketoprofeno trometamol y su utilizacion en el tratamiento topico de la inflamacion.
DE60234057D1 (de) 2001-07-25 2009-11-26 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
CN100473378C (zh) * 2002-12-17 2009-04-01 阿伯特有限及两合公司 包含非诺贝酸、其生理可接受的盐或衍生物的制剂
US20080051411A1 (en) * 2002-12-17 2008-02-28 Cink Russell D Salts of Fenofibric Acid and Pharmaceutical Formulations Thereof
EP2392258B1 (en) 2005-04-28 2014-10-08 Proteus Digital Health, Inc. Pharma-informatics system
EP1739072A1 (en) * 2005-06-15 2007-01-03 Laboratorios Menarini S.A. Polymorphic forms of dexketoprofen trometamol, preparation and pharmaceutical compositions thereof
MX2009002893A (es) 2006-09-18 2009-07-10 Raptor Pharmaceutical Inc Tratamiento de trastornos hepaticos mediante la administracion de conjugados de la proteina asociada al receptor (rap).
TWI364413B (en) * 2008-07-25 2012-05-21 Univ Nat Central Racemic ibuprofen amine salt and synthesis method thereof
BRPI0920300A2 (pt) * 2008-10-31 2020-08-11 C-A-I-R Biosciences Gmbh composto, composição farmacêutica, e, uso de um sal.
CN104208718B (zh) 2009-02-20 2017-12-29 2-Bbb医疗股份有限公司 基于谷胱甘肽的药物递送系统
EP4218718A3 (en) 2009-05-06 2024-04-24 Laboratory Skin Care, Inc. Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
ES2350670B1 (es) * 2009-06-10 2011-12-07 Polichem, S.L. Composicion veterinaria de ketoprofeno
CN101928214B (zh) * 2009-06-19 2012-12-19 黄石世星药业有限责任公司 右旋酮洛芬氨丁三醇的一种合成方法
WO2011001213A1 (en) * 2009-06-30 2011-01-06 Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Sirketi A process for preparing dexketoprofen trometamol form a and form b crystals
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
CN102557976B (zh) * 2010-12-15 2015-06-10 辽宁盛京制药有限公司 溴芬酸有机盐及其制备方法、其组合物及用途
TR201205317A2 (tr) 2011-05-18 2012-12-21 B�Lg�� Mahmut Deksketoprofen içeren efervesan formülasyonlar.
TR201104864A2 (tr) 2011-05-18 2012-12-21 Bi̇lgi̇ç Mahmut Deksketoprofen içeren suda çözünebilir formülasyonlar.
CN102381986A (zh) * 2011-07-25 2012-03-21 南京特丰药业股份有限公司 一种右旋布洛芬氨丁三醇盐及其口服溶液的制备方法
WO2013022410A2 (en) 2011-08-08 2013-02-14 Mahmut Bilgic Production method for effervescent formulations comprising dexketoprofen
WO2013095315A1 (en) 2011-12-19 2013-06-27 Mahmut Bilgic Formulations comprising dexketoprofen (particle size 300-2500 micrometer)
WO2013100877A1 (en) 2011-12-27 2013-07-04 Mahmut Bilgic Dexketoprofen formulations
ES2501415T3 (es) 2012-06-06 2016-02-22 Galenicum Health S.L. Composiciones farmacéuticas estables de acción rápida
EP2759293A1 (en) 2013-01-25 2014-07-30 Laboratorios Lesvi, S.L. Pharmaceutical compositions of (+)-(s)-2-(3-benzoylphenyl)propionic acid tromethamine salt
ES2512497T1 (es) 2013-02-06 2014-10-24 Galenicum Health S.L. Proceso para preparar una composición farmacéutica estable que comprende dexketoprofeno trometamol
ITMI20130210A1 (it) 2013-02-14 2014-08-15 Menarini Lab Composizioni farmaceutiche contenenti dexketoprofene e tramadolo
TR201616365A1 (tr) 2016-11-14 2018-05-21 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Deksketoprofen ve eletri̇ptanin oral farmasöti̇k kompozi̇syonlari
US10927067B2 (en) 2016-11-28 2021-02-23 Sarin Parayil Organic crystalline salt of haloacetic acid
TR201618765A2 (tr) 2016-12-16 2018-07-23 Imuneks Farma Ilac Sanayi Ve Ticaret Anonim Sirketi Ağrı ve enflamasyonun tedavisi için steroid olmayan anti-enflamatuvar ilaçlar ve H2 reseptörü antagonisti kombinasyonları.
KR102462607B1 (ko) * 2020-11-11 2022-11-03 대원제약주식회사 펠루비프로펜 신규 염을 주성분으로 하는 안정성이 증가된 약학적 조성물
KR102552315B1 (ko) * 2020-11-11 2023-07-06 대원제약주식회사 펠루비프로펜 신규 염을 주성분으로 하며 위장장애 부작용이 저감된 약학적 조성물
AU2023237572A1 (en) * 2022-03-25 2024-10-03 Ildong Pharmaceutical Co., Ltd. Novel salt of glp-1 receptor agonist compound, preparation method thereof and pharmaceutical composition comprising thereof

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US427996A (en) * 1890-05-13 houg-hton
FR1201726A (fr) * 1959-06-20 1960-01-05 Procédé d'obtention de dérivés flavoniques à partir des feuilles de certains végétaux
FR1546478A (fr) * 1967-01-27 1968-11-22 Rhone Poulenc Sa Nouveaux dérivés de l'acide benzoyl-3 phénylacétique et leur préparation
BR6915470D0 (pt) * 1969-03-24 1973-03-13 Syntex Corp Processo para preparar derivados de acido 2-(6'substituido 2'naftil)propionico e de seus sais
GB1408853A (en) * 1972-03-17 1975-10-08 Upjohn Co Medical process and treatment
US3821289A (en) * 1972-07-03 1974-06-28 Rorer Inc William H Tetrahydronaphthylalkanoic acids and their derivatives
GB1497044A (en) * 1974-03-07 1978-01-05 Prodotti Antibiotici Spa Salts of phenyl-alkanoic acids
US4097674A (en) * 1975-03-17 1978-06-27 Syntex Corporation 2-Naphthylacetic acid derivatives
FR2319340A1 (fr) * 1975-07-28 1977-02-25 Roussel Uclaf Nouveau sel de l'acide a-methyl benzoyl-5 thiophene-2 acetique, procede de preparation et application a titre de medicament
ES455698A1 (es) * 1977-02-07 1978-01-01 Invest Tecnica Aplicada Procedimiento para la preparacion de un nuevo derivado buta-nolaminico.
GR68102B (es) * 1978-08-08 1981-10-30 Fujisawa Pharmaceutical Co
HU185926B (en) * 1979-09-27 1985-04-28 Agostne Kahan Process for preparing water soluble derivatives of non-steroid antiinflammatory compositions and pharmaceutical compositins containing such derivatives
DE3328401A1 (de) * 1983-08-05 1985-02-21 Merckle GmbH, 7902 Blaubeuren Injizierbare loesung zur behandlung von entzuendungen
CH664563A5 (it) * 1985-04-19 1988-03-15 Seuref Ag Composti con attivita antiflogistica, antipiretica, analgesica, loro preparazione e composizioni farmaceutiche che li contengono.
IL81049A0 (en) * 1985-12-20 1987-03-31 Wisconsin Alumni Res Found Preparation of(s)-alpha-methylarylacetic acids
IT1207994B (it) * 1986-01-03 1989-06-01 Therapicon Srl Sali idrosulubili di composti adattivita' antiinfiammatoria ed analgesica, loro preparazione ed utilizzo in composizioni farmaceutiche.
US4960892A (en) * 1988-06-10 1990-10-02 American Home Products Corporation Naphthalenepropionic acid derivatives as anti-inflammatory/anti-allergic agents
US4868214A (en) * 1987-11-17 1989-09-19 Analgesic Associates Onset-hastened/enhanced analgesia
US4977181A (en) * 1987-12-18 1990-12-11 Ciba-Geigy Corporation Tromethamine salt of 1-methyl-beta-oxo-alpha-(phenylcarbamoyl)-2-pyrrolepropionitrile

Also Published As

Publication number Publication date
ES2081780T1 (es) 1996-03-16
PL175265B1 (pl) 1998-12-31
US5554789A (en) 1996-09-10
HU219975B (hu) 2001-10-28
AU674040B2 (en) 1996-12-05
JPH08503203A (ja) 1996-04-09
FI952230A (fi) 1995-05-09
CA2149013A1 (en) 1994-05-26
KR100284838B1 (ko) 2001-04-02
EP0668851B1 (en) 1997-05-28
NO2006007I1 (no) 2006-08-14
BG99609A (bg) 1996-01-31
SK280550B6 (sk) 2000-03-13
NO951790D0 (no) 1995-05-08
NO951790L (no) 1995-07-06
HK1006306A1 (en) 1999-02-19
RU95112575A (ru) 1997-06-20
BG61723B1 (bg) 1998-04-30
HUT71903A (en) 1996-02-28
ES2081780T3 (es) 1997-07-01
FI952230A0 (fi) 1995-05-09
DE69311130T2 (de) 1997-09-18
JP3778516B2 (ja) 2006-05-24
DE668851T1 (de) 1996-10-10
FI108637B (fi) 2002-02-28
ATE153649T1 (de) 1997-06-15
BR9307408A (pt) 1999-08-24
CA2149013C (en) 2004-08-10
UA44233C2 (uk) 2002-02-15
CZ286621B6 (cs) 2000-05-17
UY24179A1 (es) 1996-09-03
DE69311130D1 (de) 1997-07-03
ES2058024B1 (es) 1995-05-01
HU9501375D0 (en) 1995-06-28
HU217973B (hu) 2000-05-28
RU2128160C1 (ru) 1999-03-27
NO304306B1 (no) 1998-11-30
PL308466A1 (en) 1995-07-24
RO118712B1 (ro) 2003-09-30
EP0668851A1 (en) 1995-08-30
GR3024344T3 (en) 1997-10-31
ES2058024A1 (es) 1994-10-16
HU9802850D0 (en) 1999-02-01
MD921G2 (ro) 1998-10-31
WO1994011332A1 (en) 1994-05-26
AU5421094A (en) 1994-06-08
GR960300012T1 (en) 1996-03-31
CZ114995A3 (en) 1995-10-18
NZ257557A (en) 1996-01-26
SK60395A3 (en) 1995-09-13

Similar Documents

Publication Publication Date Title
DK0668851T3 (da) Hidtil ukendt arylpropionsyrederivat, fremgangsmåde til fremstilling heraf og anvendelse heraf som analgetisk middel
AR042345A2 (es) Un procedimiento para la preparacion de una composicion farmaceutica para el tratamiento de aterosclerosis que contiene 8.9 - dehidroesterona o sus sales de la misma
DK0935961T3 (da) Salte af (R)-2-(3-Benzoylphenyl)propionsyre og farmaceutiske præparater indeholdende disse
FI942423A0 (fi) Sakkariinijohdannisia proteolyyttisen entsyymin inhibiittoreina
DE69922703D1 (de) Ureido-thiobuttersäurederivate als ppar-agonisten
DK0471756T3 (da) Saccharinderivater, der er egnede som proteolytiske enzyminhibitorer, og fremstilling deraf
DK0710108T3 (da) Flydende, farmaceutisk præparat til oral anvendelse indeholdende 2-(4-isobutylphenyl)-propionsyre
DK0638075T3 (da) Thiazol- eller imidazolderivater som Maillard-reaktionsinhibitorer
NO980178D0 (no) Cyklo-oksygenase-inhibitor og amidin-derivatsalter, fremgangsmåte for fremstilling derav, anvendelse derav som legemidler, og farmasöytiske blandinger inneholdende slike derivater
FR2767525B1 (fr) Derives biphenyliques substitues par un radical aromatique ou heteroaromatique et compositions pharmaceutiques et cosmetiques les contenant
ES2085785T3 (es) Sales de sulfonio y proceso para su preparacion.
DK0634396T3 (da) Aminosyrederivater og deres anvendelse som enkeltfalinaseinhibitorer
DK0748222T3 (da) Hostestillende sammensætning, som indeholder hostestillende middel og benzydamin
DK0627916T3 (da) Farmaceutisk præparat, anvendeligt som analgetikum og indeholdende (R)-2-(3-benzoylphenyl)propionsyre
PT100098A (pt) Novos sais do acido 2-(2,6-dicloroanilino)-fenilacetico, processo para a sua preparacao e sua utilizacao em composicoes farmaceuticas para aplicacao topica
FI952855A0 (fi) Uudet triatsolokinatsoliinit, niiden valmistus ja käyttö
AU5269696A (en) Anellated beta-carbolines
DK597487A (da) Hyaluronsyre-tungmetalsalte til anvendelse som mikrobielle midler