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DE69730314D1 - Dosierungsform von ibuprofen - Google Patents

Dosierungsform von ibuprofen

Info

Publication number
DE69730314D1
DE69730314D1 DE69730314T DE69730314T DE69730314D1 DE 69730314 D1 DE69730314 D1 DE 69730314D1 DE 69730314 T DE69730314 T DE 69730314T DE 69730314 T DE69730314 T DE 69730314T DE 69730314 D1 DE69730314 D1 DE 69730314D1
Authority
DE
Germany
Prior art keywords
dosage form
ibuprofen
fever
bicarbonate
pain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69730314T
Other languages
English (en)
Other versions
DE69730314T2 (de
Inventor
Ashley Price
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Reckitt Benckiser Healthcare UK Ltd
Original Assignee
Boots Co PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boots Co PLC filed Critical Boots Co PLC
Application granted granted Critical
Publication of DE69730314D1 publication Critical patent/DE69730314D1/de
Publication of DE69730314T2 publication Critical patent/DE69730314T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2009Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69730314T 1996-02-21 1997-02-19 Dosierungsform von ibuprofen Expired - Lifetime DE69730314T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9603699.1A GB9603699D0 (en) 1996-02-21 1996-02-21 Therapeutic composition
GB9603699 1996-02-21
PCT/EP1997/000841 WO1997030699A2 (en) 1996-02-21 1997-02-19 Dosage form of ibuprofen

Publications (2)

Publication Number Publication Date
DE69730314D1 true DE69730314D1 (de) 2004-09-23
DE69730314T2 DE69730314T2 (de) 2005-08-18

Family

ID=10789176

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69730314T Expired - Lifetime DE69730314T2 (de) 1996-02-21 1997-02-19 Dosierungsform von ibuprofen

Country Status (25)

Country Link
US (1) US20020034540A1 (de)
EP (1) EP0881899B1 (de)
JP (2) JP2000507922A (de)
KR (1) KR19990087084A (de)
CN (1) CN1215989A (de)
AT (1) ATE273696T1 (de)
AU (1) AU722991B2 (de)
BG (1) BG64165B1 (de)
CA (1) CA2246344C (de)
CZ (1) CZ298371B6 (de)
DE (1) DE69730314T2 (de)
DK (1) DK0881899T3 (de)
ES (1) ES2227670T3 (de)
GB (1) GB9603699D0 (de)
HU (1) HUP9901454A3 (de)
IL (1) IL125803A0 (de)
NO (1) NO983825L (de)
NZ (1) NZ331416A (de)
PL (1) PL187383B1 (de)
PT (1) PT881899E (de)
RU (1) RU2182000C2 (de)
SK (1) SK285032B6 (de)
UA (1) UA55407C2 (de)
WO (1) WO1997030699A2 (de)
ZA (1) ZA971446B (de)

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US5955107A (en) * 1997-12-12 1999-09-21 Fmc Corporation Pharmaceutical suspension tablet compositions
IT1301966B1 (it) * 1998-07-30 2000-07-20 Zambon Spa Composizioni farmaceutiche ad attivita' analgesica
US20030026835A1 (en) * 1999-02-15 2003-02-06 Sumitomo Pharmaceuticals Company Limited Tablets disintegrating rapidly in the oral cavity
US6368618B1 (en) 1999-07-01 2002-04-09 The University Of Georgia Research Foundation, Inc. Composition and method for enhanced transdermal absorption of nonsteroidal anti-inflammatory drugs
NZ508292A (en) * 1999-11-24 2002-08-28 Mcneil Ppc Inc Treatment of migraine symptoms with ibuprofen and salts thereof
KR100523242B1 (ko) * 2000-05-18 2005-10-24 한미약품 주식회사 이부프로펜을 함유하는 정제 조성물
AU2002255190A1 (en) * 2001-04-10 2002-10-28 Fakhreddin Jamali Composition for enhanced absorption of nsaids
CH693586A8 (de) * 2002-10-14 2003-12-15 Roche Consumer Health Ag Darreichungsform von Ibuprofen-Natrium.
JP2006521287A (ja) * 2002-12-20 2006-09-21 エスティ.ジェイムス アソシエイト エルエルシー/フェイバー リサーチ シリーズ 医薬製剤用の高圧圧縮
US20040176234A1 (en) * 2003-03-07 2004-09-09 Baker Hughes Incorporated Method for improving separation operation of centrifuges and associated improved separation designs
US20080020042A1 (en) * 2003-10-14 2008-01-24 Peter Gruber Dosage form of sodium ibuprofen
PE20050445A1 (es) * 2003-10-30 2005-06-18 Bayer Consumer Care Ag Forma de presentacion del naproxeno sodico
US20050266031A1 (en) 2004-05-25 2005-12-01 Jay Dickerson Pharmaceutical suspension composition
US8216610B2 (en) * 2004-05-28 2012-07-10 Imaginot Pty Ltd. Oral paracetamol formulations
JP2008500288A (ja) * 2004-05-28 2008-01-10 イメイジノット ピーティーワイ エルティーディー 経口治療用化合物の供給系
ES2450648T3 (es) * 2004-06-29 2014-03-25 Takeda Pharma A/S Fabricación de composiciones farmacéuticas con liberación rápida de fármacos insolubles en agua y composiciones farmacéuticas obtenidas mediante el procedimiento de la invención
JP2008509206A (ja) * 2004-08-12 2008-03-27 レキット ベンキーザー ヘルスケア (ユーケイ) リミテッド 溶融押出しにより作製するnsaid及び糖アルコールを含む顆粒
CN101068532B (zh) * 2004-09-30 2012-03-14 斯科尔医药公司 布洛芬改进释放剂型
US20070077297A1 (en) 2004-09-30 2007-04-05 Scolr Pharma, Inc. Modified release ibuprofen dosage form
US20060068009A1 (en) * 2004-09-30 2006-03-30 Scolr Pharma, Inc. Modified release ibuprofen dosage form
CA2589079A1 (en) * 2004-11-03 2006-06-01 Equitech Corporation Nsaid compositions exhibiting clinical superiority
DK1850834T3 (da) * 2005-02-09 2014-11-10 Boehringer Ingelheim Int Filmovertrykket tablet indeholdende ibufrofen-lysinat
EP1800667A1 (de) 2005-12-23 2007-06-27 Losan Pharma GmbH Schnell lösliches Ibuprofen-Granulat
EP1863460B1 (de) 2005-03-22 2013-01-16 Losan Pharma GmbH Gelöstes ibuprofen
EP1926481A2 (de) * 2005-09-19 2008-06-04 Albermarle Corporation Hochkonzentrierte giessbare wässrige lösungen von kalium-ibuprofen, ihre herstellung und verwendung
US7811604B1 (en) 2005-11-14 2010-10-12 Barr Laboratories, Inc. Non-effervescent, orally disintegrating solid pharmaceutical dosage forms comprising clozapine and methods of making and using the same
EP3263117A1 (de) 2005-11-28 2018-01-03 Imaginot Pty Ltd. Abgabesystem für eine orale therapeutische verbindung
KR101288924B1 (ko) * 2006-08-16 2013-07-24 에스에스 세야쿠 가부시키 가이샤 경구투여용 제제
FI20080348A0 (fi) * 2008-02-15 2008-05-09 Atacama Labs Oy Uudenlainen farmaseuttinen formulaatio
US8951562B2 (en) 2006-11-10 2015-02-10 Atacama Labs Oy Method and apparatus or dry granulation
FI20070521L (fi) * 2006-11-10 2008-05-11 Atacama Labs Oy Rakeita, tabletteja ja rakeistusmenetelmä
US7749537B2 (en) 2006-12-04 2010-07-06 Scolr Pharma, Inc. Method of forming a tablet
CA2674776A1 (en) * 2006-12-20 2008-07-03 Duramed Pharmaceuticals, Inc. Orally disintegrating solid dosage forms comprising progestin and methods of making and use thereof
EP2291233B1 (de) * 2008-05-09 2019-09-04 Atacama Labs Oy Verfahren für trockene granulation
EP2309988B1 (de) 2008-07-21 2015-11-25 SI Group, Inc. Granulat mit hohem ibuprofen-natriumgehalt, seine herstellung und seine verwendung bei der herstellung von nichtsprudelnden festen dosierformen
US9629809B2 (en) 2008-07-21 2017-04-25 Si Group, Inc. High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms
WO2011001228A1 (en) * 2008-08-14 2011-01-06 Shasun Chemicals And Drugs Limited Aryl alkyl carboxylic acid salts, process for preparation and dosage forms
CA2764740C (en) * 2009-06-22 2015-09-01 Wyeth Llc Sodium ibuprofen tablets and methods of manufacturing pharmaceutical compositions including sodium ibuprofen
AU2015264861C1 (en) * 2009-06-22 2017-11-16 Pf Consumer Healthcare 1 Llc Sodium ibuprofen tablets and methods of manufacturing pharmaceutical compositions including sodium ibuprofen
AU2014200704C1 (en) * 2009-06-22 2018-12-06 Pf Consumer Healthcare 1 Llc Sodium ibuprofen tablets and methods of manufacturing pharmaceutical compositions including sodium ibuprofen
JP5974469B2 (ja) * 2010-12-24 2016-08-23 ライオン株式会社 錠剤の製造方法
CN103102259B (zh) * 2011-12-23 2014-02-26 海南正瑞医药科技开发有限公司 一种布洛芬水合物晶体、及含该水合物晶体的药物组合物及其制备方法
WO2015016256A1 (ja) * 2013-07-30 2015-02-05 ライオン株式会社 錠剤
EP2845850A1 (de) 2013-09-10 2015-03-11 ObsEva S.A. Pyrrolidinderivate als Oxytocin/Vasopressin-V1a-Rezeptorantagonisten
EP2886107A1 (de) * 2013-12-17 2015-06-24 ObsEva S.A. Orale Formulierungen von Pyrrolydinderivaten
CN106795110A (zh) 2014-07-02 2017-05-31 奥布赛瓦股份公司 治疗ot‑r活性相关的病症的方法中可用的晶体(3z,5s)‑5‑(羟甲基)‑1‑[(2’‑甲基‑1,1’‑联苯‑4‑基)羰基]吡咯烷‑3‑酮o‑甲基肟
EP2965746B1 (de) 2014-07-10 2019-03-13 Santa Farma Ilaç Sanayi A.S. Orale pharmazeutische Zusammensetzung mit Ibuprofen, Ibuprofennatriumdihydrat, Pseudoephedrinhydrochlorid und Chlorpheniraminmaleat
WO2017060920A1 (en) * 2015-10-05 2017-04-13 Strides Shasun Limited Pharmaceutical compositions

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4837031A (en) * 1987-09-17 1989-06-06 Mallinckrodt, Inc. Compositions containing ibuprofen
DE3922441A1 (de) * 1989-07-07 1991-01-17 Pharmatrans Sanaq Ag Ibuprofen- und s-(+)-ibuprofen-zubereitungen und verfahren zu ihrer herstellung
GEP20002013B (en) * 1991-05-13 2000-04-10 Boots Co Plc Therapeutical Means
DE4216756C2 (de) * 1992-05-21 1994-08-25 Pharmatrans Sanaq Ag 2-Arylpropionsäure-Zubereitungen und Verfahren zu ihrer Herstellung
DE59209706D1 (de) * 1992-12-01 1999-07-08 Spirig Ag S(+)-Ibuprofen enthaltende Arzneimittel

Also Published As

Publication number Publication date
NZ331416A (en) 2000-02-28
WO1997030699A3 (en) 1997-10-09
IL125803A0 (en) 1999-04-11
CA2246344C (en) 2009-01-20
NO983825D0 (no) 1998-08-20
AU1793797A (en) 1997-09-10
ATE273696T1 (de) 2004-09-15
AU722991B2 (en) 2000-08-17
JP2009073847A (ja) 2009-04-09
JP2000507922A (ja) 2000-06-27
EP0881899B1 (de) 2004-08-18
DE69730314T2 (de) 2005-08-18
ZA971446B (en) 1997-11-25
PL328465A1 (en) 1999-02-01
CA2246344A1 (en) 1997-08-28
DK0881899T3 (da) 2004-12-20
BG64165B1 (bg) 2004-03-31
US20020034540A1 (en) 2002-03-21
PT881899E (pt) 2004-12-31
ES2227670T3 (es) 2005-04-01
GB9603699D0 (en) 1996-04-17
SK114298A3 (en) 1999-01-11
UA55407C2 (uk) 2003-04-15
CN1215989A (zh) 1999-05-05
CZ298371B6 (cs) 2007-09-12
BG102744A (en) 1999-05-31
SK285032B6 (sk) 2006-05-04
CZ261798A3 (cs) 1998-11-11
RU2182000C2 (ru) 2002-05-10
WO1997030699A2 (en) 1997-08-28
KR19990087084A (ko) 1999-12-15
NO983825L (no) 1998-10-20
PL187383B1 (pl) 2004-06-30
HUP9901454A2 (hu) 1999-08-30
EP0881899A2 (de) 1998-12-09
HUP9901454A3 (en) 2001-04-28

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: RECKITT BENCKISER HEALTHCARE INTERNATIONAL LTD, GB

8327 Change in the person/name/address of the patent owner

Owner name: RECKITT BENCKISER HEALTHCARE (UK) LTD., SLOUGH, GB