CY1319A - Oximes derived from erythromycin a,their preparation,their application in pharmaceuticals and pharmaceutical compositions containing them - Google Patents

Oximes derived from erythromycin a,their preparation,their application in pharmaceuticals and pharmaceutical compositions containing them

Info

Publication number: CY1319A
Authority: CY; Cyprus
Prior art keywords: erythromycin; pharmaceuticals; preparation; application; pharmaceutical compositions
Prior art date: 1980-01-11

Application number

CY1319A

Other languages

English (en)

Inventor

D Ambrieres Solange Gouin

Andre Lutz

Jean-Claude Gasc

Original Assignee

Roussel Uclaf

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-01-11

Filing date

1981-01-09

Publication date

1986-03-28

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9237443&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1319(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1981-01-09 Application filed by Roussel Uclaf filed Critical Roussel Uclaf

1986-03-28 Publication of CY1319A publication Critical patent/CY1319A/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)

CY1319A 1980-01-11 1981-01-09 Oximes derived from erythromycin a,their preparation,their application in pharmaceuticals and pharmaceutical compositions containing them CY1319A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR8000566A FR2473525A1 (fr)	1980-01-11	1980-01-11	Nouvelles oximes derivees de l'erythromycine, leur procede de preparation et leur application comme medicaments

Publications (1)

Publication Number	Publication Date
CY1319A true CY1319A (en)	1986-03-28

Family

ID=9237443

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CY1319A CY1319A (en)	1980-01-11	1981-01-09	Oximes derived from erythromycin a,their preparation,their application in pharmaceuticals and pharmaceutical compositions containing them

Country Status (25)

Country	Link
US (1)	US4349545A (zh)
EP (1)	EP0033255B1 (zh)
JP (1)	JPS56100799A (zh)
KR (1)	KR850000964B1 (zh)
AU (1)	AU537247B2 (zh)
BG (1)	BG61369B2 (zh)
CA (1)	CA1162535A (zh)
CY (1)	CY1319A (zh)
DE (1)	DE3165720D1 (zh)
DK (1)	DK157878C (zh)
ES (1)	ES8200702A1 (zh)
FI (1)	FI69473C (zh)
FR (1)	FR2473525A1 (zh)
GR (1)	GR73103B (zh)
GT (1)	GT198500080A (zh)
HK (1)	HK586A (zh)
HU (1)	HU187760B (zh)
IE (1)	IE50680B1 (zh)
IL (1)	IL61808A (zh)
LU (1)	LU88283I2 (zh)
MY (1)	MY8500984A (zh)
NL (1)	NL930097I2 (zh)
OA (1)	OA06719A (zh)
PT (1)	PT72331B (zh)
ZA (1)	ZA808108B (zh)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2534588B2 (fr) *	1982-10-15	1985-09-20	Roussel Uclaf	Nouvelles oximes derivees de l'erythromycine, leur procede de preparation et leur application comme medicaments
US4526889A (en) *	1982-11-15	1985-07-02	Pfizer Inc.	Epimeric azahomoerythromycin A derivative, intermediates and method of use
DK149776C (da) *	1984-01-06	1987-04-21	Orion Yhtymae Oy	Antibiotisk virksom erytromycinforbindelse og praeparat indeholdende forbindelsen
JPS60214796A (ja) *	1984-04-06	1985-10-28	Taisho Pharmaceut Co Ltd	６−０−メチルエリスロマイシン類の製法
JPS61103890A (ja) *	1984-10-26	1986-05-22	Taisho Pharmaceut Co Ltd	６−０−メチルエリスロマイシンａ誘導体
NO860901L (no)	1985-03-12	1986-09-15	Beecham Group Plc	Fremgangsmaate for fremstilling av farmasoeytisk aktive erytromycinderivater.
JPS61229895A (ja) *	1985-04-03	1986-10-14	Nippon Zeon Co Ltd	保護化デス−ｎ−メチルエリスロマイシン誘導体
US4740502A (en) *	1986-06-20	1988-04-26	Abbott Laboratories	Semisynthetic erythromycin antibiotics
DE3782994T2 (de)	1986-09-18	1993-04-08	Taisho Pharma Co Ltd	Erythromycin-a-derivate und verfahren zu ihrer herstellung.
JP2751385B2 (ja) *	1988-05-19	1998-05-18	大正製薬株式会社	エリスロマイシンａオキシム及びその塩の製造方法
US5075289A (en) *	1988-06-07	1991-12-24	Abbott Laboratories	9-r-azacyclic erythromycin antibiotics
US5302705A (en) *	1989-10-07	1994-04-12	Taisho Pharmaceutical Co., Ltd.	6-O-methylerythromycin a oxime derivatives
EP0503932B1 (en)	1991-03-15	1998-12-02	Merck & Co. Inc.	9-Deoxo-9(z)-hydroxy-iminoerythromycin A and O-derivatives thereof
US5912331A (en) *	1991-03-15	1999-06-15	Merck & Co., Inc.	Process for the preparation of 9-deoxo-9(Z)-hydroxyiminoerythromycin A
US5985844A (en) *	1992-03-26	1999-11-16	Merck & Co., Inc.	Homoerythromycin A derivatives modified at the 4"-and 8A-positions
US5189159A (en) *	1992-04-02	1993-02-23	Merck & Co., Inc.	8a-AZA-8a-homoerythromycin cyclic iminoethers
ES2036472B1 (es) *	1991-10-01	1994-03-01	Prodesfarma Sa	Procedimiento de obtencion de eritromicina 9-(0-((2-metoxietoxi)metil)oxima) (roxitromicina).
US5210235A (en) *	1992-08-26	1993-05-11	Merck & Co., Inc.	Methods of elaborating erythromycin fragments into amine-containing fragments of azalide antibiotics
US5332807A (en) *	1993-04-14	1994-07-26	Merck & Co., Inc.	Process of producing 8A- and 9A-azalide antibiotics
KR970702725A (ko) *	1994-04-26	1997-06-10	노부히로 나리따	비소세포 폐암 치료용 의약 조성물(Medicinal Composition as a Remedy for Nonsmall Cell Lung Cancer)
IT1276901B1 (it) *	1994-12-13	1997-11-03	Zambon Spa	Derivati dell'eritromicina a 9-0-ossina dotati di attivita' antibiotica
US5872229A (en)	1995-11-21	1999-02-16	Abbott Laboratories	Process for 6-O-alkylation of erythromycin derivatives
FR2760017B1 (fr) *	1997-02-27	1999-04-30	Hoechst Marion Roussel Inc	Nouveaux derives de l'erytromycine, leur procede de preparation et leur application comme medicaments
US5929219A (en)	1997-09-10	1999-07-27	Abbott Laboratories	9-hydrazone and 9-azine erythromycin derivatives and a process of making the same
PT102202B (pt) *	1998-09-10	2001-04-30	Hovione Sociedade Quimica S A	Processo para a purificacao de roxitromicina
IN190782B (zh) *	1998-09-30	2003-08-23	Max India Ltd
DE69813244T2 (de) *	1998-11-24	2004-03-04	Jubilant Organosys Ltd.	Verfahren zur Herstellung von Roxithromycin und Derivate davon
IL150227A0 (en) *	1999-12-16	2002-12-01	Teva Pharma	Processes for preparing clarithromycin polymorphs and novel polymorph iv
AU2261901A (en)	2000-01-11	2001-07-24	Teva Pharma	Processes for preparing clarithromycin polymorphs
HUP0302466A2 (hu) *	2000-02-29	2003-11-28	Teva Pharmaceutical Industries Ltd.	Eljárások clarithromycin, clarithromycin intermedier, gyakorlatilag oximmentes clarithromycin és ezt tartalmazó gyógyszerkészítmény előállítására
HRP20020885B1 (en)	2002-11-11	2007-05-31	GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o.	SUBSTITUTED 9a-N-{N'-[4-(SULFONYL)PHENYLCARBAMOYL]}DERIVATIVES 9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERITHROMYCIN A AND 5-O-DESOZAMINYL-9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERITHRONOLIDE A
HRP20020991A2 (en)	2002-12-12	2005-02-28	Pliva-Istra�iva�ki institut d.o.o.	N"-Substituted 9a-N-(N'-carbamoyl-Gamma-aminopropyl), 9a-N-(N'? -thiocarbamoyl-Gamma-aminopropyl), 9a-N-(N'-((Beta-cyanoethyl)-N'-carbamoyl-Gamma? -aminopropyl) and 9a-N-(N'-(Beta-cyanoethyl)-N'-thiocarbamoyl-Gamma? -aminopropyl) derivatives of 9-de
AU2003271408B2 (en) *	2002-12-31	2008-07-17	Alembic Limited	A process for the purification of roxithromycin
CN101541331A (zh)	2006-08-24	2009-09-23	沃克哈特研究中心	具有抗微生物活性的新颖大环内酯和酮内酯
US20090005326A1 (en) *	2007-06-26	2009-01-01	Idexx Laboratories, Inc.	Single dose roxithromycin
CA2820451C (en)	2010-12-09	2017-12-12	Wockhardt Limited	Ketolide compounds
WO2012117357A2 (en)	2011-03-01	2012-09-07	Wockhardt Limited	Process for preparation of ketolide intermediates
WO2012127351A1 (en)	2011-03-22	2012-09-27	Wockhardt Limited	Process for preparation of ketolide compounds
CN102219816A (zh) *	2011-05-12	2011-10-19	浙江国邦药业有限公司	一种罗红霉素的纯化方法
PL222631B1 (pl)	2012-11-14	2016-08-31	Gdański Univ Medyczny	Kompozycja farmaceutyczna zawierająca roksytromycynę, sposób jej wytwarzania oraz zastosowanie medyczne tej kompozycji i produkt leczniczy zawierający kompozycję
CN104163840A (zh) *	2013-08-30	2014-11-26	郑州后羿制药有限公司	一种罗红霉素的精制方法
FR3049861A1 (fr)	2016-04-07	2017-10-13	Univ Claude Bernard Lyon	Nouvelles compositions antivirales pour le traitement de la grippe

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
YU31319B (en) *	1967-08-03	1973-04-30	Pliva Pharm & Chem Works	Postupak za dobijanje acil derivata eritromicin oksima
US3869444A (en) *	1972-10-10	1975-03-04	Abbott Lab	Esters of erythromycin oxime
ES434842A1 (es) *	1975-02-19	1976-12-01	Andreu Sa Dr	Procedimiento para la preparacion de esteres de la oxima deeritromicina.
DK139522C (da) *	1975-04-07	1979-08-20	Thomae Gmbh Dr K	Analogifremgangsmaade til fremstilling af 9-iminoalkylamino-erythromyciner eller syreadditionssalte deraf
DE2515077A1 (de) *	1975-04-07	1976-10-28	Thomae Gmbh Dr K	Neue 9-alkylidenamino-erythromycine, ihre salze und verfahren zu ihrer herstellung
DE2515076A1 (de) *	1975-04-07	1976-10-28	Thomae Gmbh Dr K	Neue erythromycinderivate, deren salze und verfahren zu ihrer herstellung
DE2750288A1 (de) *	1977-11-10	1979-05-17	Thomae Gmbh Dr K	Neue 9-(omega-heteroarylamino- alkylamino)-erythromycine, ihre salze, verfahren zu ihrer herstellung und diese enthaltende arzneimittel

1980
- 1980-01-11 FR FR8000566A patent/FR2473525A1/fr active Granted
- 1980-12-26 IL IL61808A patent/IL61808A/xx not_active IP Right Cessation
- 1980-12-30 ZA ZA00808108A patent/ZA808108B/xx unknown
1981
- 1981-01-08 US US06/223,368 patent/US4349545A/en not_active Expired - Lifetime
- 1981-01-08 FI FI810042A patent/FI69473C/fi not_active IP Right Cessation
- 1981-01-09 AU AU66131/81A patent/AU537247B2/en not_active Expired
- 1981-01-09 HU HU8155A patent/HU187760B/hu unknown
- 1981-01-09 ES ES498395A patent/ES8200702A1/es not_active Expired
- 1981-01-09 EP EP81400026A patent/EP0033255B1/fr not_active Expired
- 1981-01-09 CY CY1319A patent/CY1319A/xx unknown
- 1981-01-09 DK DK007881A patent/DK157878C/da active
- 1981-01-09 OA OA57295A patent/OA06719A/xx unknown
- 1981-01-09 DE DE8181400026T patent/DE3165720D1/de not_active Expired
- 1981-01-09 GR GR63831A patent/GR73103B/el unknown
- 1981-01-09 PT PT72331A patent/PT72331B/pt unknown
- 1981-01-09 CA CA000368249A patent/CA1162535A/fr not_active Expired
- 1981-01-09 JP JP126481A patent/JPS56100799A/ja active Granted
- 1981-01-09 IE IE46/81A patent/IE50680B1/en not_active IP Right Cessation
- 1981-01-10 KR KR1019810000051A patent/KR850000964B1/ko active
1985
- 1985-09-12 GT GT198500080A patent/GT198500080A/es unknown
- 1985-12-30 MY MY984/85A patent/MY8500984A/xx unknown
1986
- 1986-01-02 HK HK5/86A patent/HK586A/xx not_active IP Right Cessation
1993
- 1993-06-03 LU LU88283C patent/LU88283I2/fr unknown
- 1993-06-25 NL NL930097C patent/NL930097I2/nl unknown
1994
- 1994-02-22 BG BG098506A patent/BG61369B2/bg unknown

Also Published As

Publication number	Publication date
AU537247B2 (en)	1984-06-14
HK586A (en)	1986-01-10
IL61808A (en)	1986-12-31
FI810042L (fi)	1981-07-12
ZA808108B (en)	1982-01-27
JPS56100799A (en)	1981-08-12
DK157878B (da)	1990-02-26
EP0033255B1 (fr)	1984-08-29
IE810046L (en)	1981-07-11
IL61808A0 (en)	1981-01-30
FR2473525B1 (zh)	1983-04-15
NL930097I2 (nl)	1995-04-03
FR2473525A1 (fr)	1981-07-17
ES498395A0 (es)	1981-11-01
US4349545A (en)	1982-09-14
NL930097I1 (nl)	1993-10-01
FI69473C (fi)	1986-02-10
LU88283I2 (fr)	1994-09-09
PT72331B (fr)	1982-07-23
KR850000964B1 (ko)	1985-07-02
BG61369B2 (bg)	1997-06-30
FI69473B (fi)	1985-10-31
ES8200702A1 (es)	1981-11-01
CA1162535A (fr)	1984-02-21
OA06719A (fr)	1982-06-30
IE50680B1 (en)	1986-06-11
DK157878C (da)	1990-07-30
AU6613181A (en)	1981-07-16
GT198500080A (es)	1987-03-06
EP0033255A1 (fr)	1981-08-05
JPS6237639B2 (zh)	1987-08-13
HU187760B (en)	1986-02-28
MY8500984A (en)	1985-12-31
DK7881A (da)	1981-07-12
PT72331A (fr)	1981-02-01
KR830005258A (ko)	1983-08-03
GR73103B (zh)	1984-02-02
DE3165720D1 (en)	1984-10-04

Publication	Publication Date	Title
DE3165720D1 (en)	1984-10-04	Oximes derived from erythromycin a, their preparation, their application in pharmaceuticals and pharmaceutical compositions containing them
IL66099A0 (en)	1982-09-30	N-aryl-piperazinealkanamides,their preparation and pharmaceutical compositions containing them
DE3263633D1 (en)	1985-06-13	Imidazodiazepines, process for their preparation and pharmaceutical compositions containing them
IL65257A0 (en)	1983-12-30	Arylcyclo-butanealkylamine derivatives,their preparation and pharmaceutical compositions containing them
IL67826A0 (en)	1983-06-15	Pyrazolooxazines,pyrazolothiazines and pyrazoloquinolines,their preparation and pharmaceutical compositions containing them
IL64777A0 (en)	1982-03-31	3-aminopropoxyaryl derivatives,their preparation and pharmaceutical compositions containing them
IL66683A0 (en)	1982-12-31	Benzo-heterocycles,their preparation and pharmaceutical compositions containing them
IL66408A (en)	1985-12-31	3-amino-pyridazine derivatives,their preparation and pharmaceutical compositions containing them
ZA818371B (en)	1983-08-31	Nortropanols,their preparation and pharmaceutical compositions containing these
IL67180A0 (en)	1983-03-31	Morphinate derivatives,their preparation and pharmaceutical compositions containing them
IL60678A0 (en)	1980-09-16	3-amino-syndone-imines, their preparation and pharmaceutical compositions containing them
IL63368A0 (en)	1981-10-30	4,5-diaryl-alpha-polyfluoroalkyl-1h-imidazole-2-methanamines,their preparation and pharmaceutical compositions containing them
IL68497A0 (en)	1983-07-31	Benzoazacycloalkyl-spiro-imidazolidines,their preparation and pharmaceutical compositions containing them
IL64498A0 (en)	1982-03-31	Phenylalkylamines,their preparation and pharmaceutical compositions containing them
IL60918A (en)	1983-11-30	6-pyridazinones,their preparation and pharmaceutical compositions containing them
ZA816844B (en)	1982-09-29	Substituted iminodiacids,their preparation and pharmaceutical compositions containing them
IL66227A0 (en)	1982-11-30	Amidobenzamides and their salts,their preparation and pharmaceutical compositions containing them
ZA827055B (en)	1984-05-30	Substituted ethylamines,processes for their preparation,and pharmaceutical compositions thereof
IL65422A (en)	1985-04-30	2-piperazino-pyrimidine derivatives,their preparation and pharmaceutical compositions containing them
IL64563A0 (en)	1982-03-31	3,4-bis-substituted 1,2,5-oxidiazole 2-oxides,their preparation and pharmaceutical compositions containing them
IL64252A (en)	1985-02-28	3,3-dimethyl-indolin-2-ones,their preparation and pharmaceutical compositions containing them
IL65177A0 (en)	1982-05-31	Fluoroprostacylins,their preparation and pharmaceutical compositions containing them
IL66385A0 (en)	1982-11-30	Benzotriazoles,their preparation and pharmaceutical compositions containing them
IL65653A0 (en)	1982-07-30	Aminocyclitol derivatives,their preparation and pharmaceutical compositions containing them
EP0018077A3 (en)	1980-11-26	Phenylmorphans, processes for their preparation, pharmaceutical compositions containing them, and 4-phenyl-tetrahydro-pyridines