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ES2036472B1 - Procedimiento de obtencion de eritromicina 9-(0-((2-metoxietoxi)metil)oxima) (roxitromicina). - Google Patents

Procedimiento de obtencion de eritromicina 9-(0-((2-metoxietoxi)metil)oxima) (roxitromicina).

Info

Publication number
ES2036472B1
ES2036472B1 ES9102152A ES9102152A ES2036472B1 ES 2036472 B1 ES2036472 B1 ES 2036472B1 ES 9102152 A ES9102152 A ES 9102152A ES 9102152 A ES9102152 A ES 9102152A ES 2036472 B1 ES2036472 B1 ES 2036472B1
Authority
ES
Spain
Prior art keywords
roxythromycin
methyl
procedure
erythromycin
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES9102152A
Other languages
English (en)
Other versions
ES2036472A1 (es
Inventor
Cruz Alba Agusti
Vilarelle Eduardo Elias
Marti Antonio Ginebra
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Prodesfarma SA
Original Assignee
Prodesfarma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prodesfarma SA filed Critical Prodesfarma SA
Priority to ES9102152A priority Critical patent/ES2036472B1/es
Priority to PT10091392A priority patent/PT100913A/pt
Publication of ES2036472A1 publication Critical patent/ES2036472A1/es
Application granted granted Critical
Publication of ES2036472B1 publication Critical patent/ES2036472B1/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Landscapes

  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE ERITROMICINA 9-[0-[(2METOXIETOXI)METIL] OXIMA], DENOMINADA ROXITROMICINA, DE FORMULA I, BASADO EN TRATAR CON UNA BASE ORGANICA, PREFERENTEMENTE UN CARBONATO DE METAL ALCALINO O ALCALINO TERREO, UNA SAL DE 2-METOXIETOXIMETILAMONIO DE LA ERITROMICINA 9-OXIMA DE FORMULA V FORMULA DONDE X- SIGNIFICA UN ANION DERIVADO DE UN ACIDO MINERAL U ORGANICO; EL PROCESO TIENE LUGAR EN EL SENO DE UN DISOLVENTE POLAR NO ALCOHOLICO. LA ROXITROMICINA MUESTRA ACTIVIDAD ANTIBIOTICA FRENTE A BACTERIAS GRAM POSITIVAS.
ES9102152A 1991-10-01 1991-10-01 Procedimiento de obtencion de eritromicina 9-(0-((2-metoxietoxi)metil)oxima) (roxitromicina). Expired - Fee Related ES2036472B1 (es)

Priority Applications (2)

Application Number Priority Date Filing Date Title
ES9102152A ES2036472B1 (es) 1991-10-01 1991-10-01 Procedimiento de obtencion de eritromicina 9-(0-((2-metoxietoxi)metil)oxima) (roxitromicina).
PT10091392A PT100913A (pt) 1991-10-01 1992-09-29 Processo para a obtencao de eritromicina 9-{o-{(2-metoxietoxi)metil} oxima} (roxitromicina)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9102152A ES2036472B1 (es) 1991-10-01 1991-10-01 Procedimiento de obtencion de eritromicina 9-(0-((2-metoxietoxi)metil)oxima) (roxitromicina).

Publications (2)

Publication Number Publication Date
ES2036472A1 ES2036472A1 (es) 1993-05-16
ES2036472B1 true ES2036472B1 (es) 1994-03-01

Family

ID=8273673

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9102152A Expired - Fee Related ES2036472B1 (es) 1991-10-01 1991-10-01 Procedimiento de obtencion de eritromicina 9-(0-((2-metoxietoxi)metil)oxima) (roxitromicina).

Country Status (2)

Country Link
ES (1) ES2036472B1 (es)
PT (1) PT100913A (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT102202B (pt) * 1998-09-10 2001-04-30 Hovione Sociedade Quimica S A Processo para a purificacao de roxitromicina
DE69813244T2 (de) * 1998-11-24 2004-03-04 Jubilant Organosys Ltd. Verfahren zur Herstellung von Roxithromycin und Derivate davon

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2473525A1 (fr) * 1980-01-11 1981-07-17 Roussel Uclaf Nouvelles oximes derivees de l'erythromycine, leur procede de preparation et leur application comme medicaments

Also Published As

Publication number Publication date
ES2036472A1 (es) 1993-05-16
PT100913A (pt) 1993-11-30

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20000603