CS209815B2 - Method of making the new phenetanolamines - Google Patents
Method of making the new phenetanolamines Download PDFInfo
- Publication number
- CS209815B2 CS209815B2 CS794632A CS463279A CS209815B2 CS 209815 B2 CS209815 B2 CS 209815B2 CS 794632 A CS794632 A CS 794632A CS 463279 A CS463279 A CS 463279A CS 209815 B2 CS209815 B2 CS 209815B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- compounds
- administered
- mixture
- weight
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/06—Preparation of carboxylic acid nitriles from N-formylated amino compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/38—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
- C07C243/24—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids
- C07C243/38—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
- C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
- C07C29/147—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/42—Separation; Purification; Stabilisation; Use of additives
- C07C51/487—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/04—Compounds containing oxirane rings containing only hydrogen and carbon atoms in addition to the ring oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Obesity (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Fodder In General (AREA)
- Dairy Products (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US92167078A | 1978-07-03 | 1978-07-03 |
Publications (1)
Publication Number | Publication Date |
---|---|
CS209815B2 true CS209815B2 (en) | 1981-12-31 |
Family
ID=25445792
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CS794632A CS209815B2 (en) | 1978-07-03 | 1979-07-02 | Method of making the new phenetanolamines |
CS794631A CS208664B2 (en) | 1978-07-03 | 1979-07-02 | Method of making the new r,s-n-/2-phenyl-2-hydroxyethyl/-1-alkyl-3-/4-substituted phenyl/propylamines |
CS794631A CS208663B2 (en) | 1978-07-03 | 1979-07-02 | Method of making the new r,s-n-/2-phenyl-2-hydroxyethyl0 -1-alkyl-3-/4-substituted phenyl/propylamines |
CS794631A CS208662B2 (en) | 1978-07-03 | 1979-07-02 | Method of making the new r,s-n-/2-phenyl-2-hydroxyethyl/-1-apkyl-3-/4-substituted fenyl/propalamines |
Family Applications After (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CS794631A CS208664B2 (en) | 1978-07-03 | 1979-07-02 | Method of making the new r,s-n-/2-phenyl-2-hydroxyethyl/-1-alkyl-3-/4-substituted phenyl/propylamines |
CS794631A CS208663B2 (en) | 1978-07-03 | 1979-07-02 | Method of making the new r,s-n-/2-phenyl-2-hydroxyethyl0 -1-alkyl-3-/4-substituted phenyl/propylamines |
CS794631A CS208662B2 (en) | 1978-07-03 | 1979-07-02 | Method of making the new r,s-n-/2-phenyl-2-hydroxyethyl/-1-apkyl-3-/4-substituted fenyl/propalamines |
Country Status (31)
Country | Link |
---|---|
EP (3) | EP0007204B1 (fr) |
JP (2) | JPS559096A (fr) |
KR (1) | KR880002310B1 (fr) |
AR (4) | AR229080A1 (fr) |
AT (2) | AT367025B (fr) |
AU (2) | AU523720B2 (fr) |
BE (2) | BE877394A (fr) |
BG (4) | BG31647A3 (fr) |
CA (2) | CA1142954A (fr) |
CH (2) | CH642618A5 (fr) |
CS (4) | CS209815B2 (fr) |
DD (2) | DD144761A5 (fr) |
DE (2) | DE2964604D1 (fr) |
DK (2) | DK160936C (fr) |
EG (1) | EG14238A (fr) |
ES (4) | ES482155A1 (fr) |
FI (2) | FI792081A (fr) |
FR (3) | FR2430410B1 (fr) |
GB (3) | GB2101582B (fr) |
GR (2) | GR72940B (fr) |
HU (2) | HU179171B (fr) |
IE (2) | IE48769B1 (fr) |
IL (2) | IL57672A (fr) |
LU (2) | LU81457A1 (fr) |
NZ (2) | NZ190861A (fr) |
PH (2) | PH14522A (fr) |
PL (4) | PL117551B1 (fr) |
PT (2) | PT69843A (fr) |
RO (4) | RO77732A (fr) |
SU (4) | SU965350A3 (fr) |
ZA (2) | ZA793297B (fr) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0006735B1 (fr) * | 1978-06-28 | 1983-06-15 | Beecham Group Plc | Amines secondaires, procédé pour leur préparation, compositions pharmaceutiques les contenant et leur utilisation |
DE3061693D1 (en) * | 1979-10-25 | 1983-02-24 | Beecham Group Plc | Secondary amines, their preparation and use in pharmaceutical compositions |
EP0029320B1 (fr) * | 1979-11-15 | 1985-07-10 | Beecham Group Plc | Ethanolamines secondaires, leur préparation et leur utilisation dans des compositions pharmaceutiques |
DE3161165D1 (en) * | 1980-05-08 | 1983-11-17 | Beecham Group Plc | Arylethanolamine derivatives, their preparation and use in pharmaceutical compositions |
DE3264364D1 (en) * | 1981-03-06 | 1985-08-01 | Beecham Group Plc | Arylethanol amine derivatives, their preparation and use in pharmaceutical compositions |
EP0061907B1 (fr) * | 1981-03-31 | 1984-08-01 | Beecham Group Plc | Amines secondaires, leur préparation, compositions pharmaceutiques les contenant et leur utilisation |
DE3271132D1 (en) * | 1981-07-11 | 1986-06-19 | Beecham Group Plc | Secondary phenylethanol amines, processes for their preparation and their pharmaceutical application |
EP0089154A3 (fr) * | 1982-03-12 | 1984-08-08 | Beecham Group Plc | Dérivés d'éthanolamine, leur fabrication et leur utilisation en compositions pharmaceutiques |
CA1219865A (fr) * | 1982-05-14 | 1987-03-31 | Leo Alig | Derives de phenethanolamine d'aziridine |
CA1258454A (fr) * | 1982-08-10 | 1989-08-15 | Leo Alig | Phenethanolamines |
JPS5980640A (ja) * | 1982-09-27 | 1984-05-10 | イーライ・リリー・アンド・カンパニー | 2−ヒドロキシ−2−フエニルエチルアミン類の製造方法 |
DE3473439D1 (en) * | 1983-01-31 | 1988-09-22 | Lilly Co Eli | Improvements in or relating to phenethanolamines |
CA1262729A (fr) * | 1983-10-19 | 1989-11-07 | Leo Alig | Phenoxypropanolamines |
US5166218A (en) * | 1983-10-19 | 1992-11-24 | Hoffmann-La Roche Inc. | Phenoxypropanolamines and pharmaceutical compositions thereof |
US4602044A (en) * | 1983-12-19 | 1986-07-22 | Eli Lilly And Company | β-phenethanolamine antiobesity agents |
EP0151513A1 (fr) * | 1984-01-12 | 1985-08-14 | Eli Lilly And Company | Agents inotropes |
ES8800842A1 (es) * | 1985-03-01 | 1987-12-01 | Beecham Group Plc | Un procedimiento para preparar una formulacion veterinariamente aceptable de ariletanolaminas promotora del crecimiento. |
GB8505284D0 (en) * | 1985-03-01 | 1985-04-03 | Beecham Group Plc | Growth promoters |
IT1204416B (it) * | 1986-06-27 | 1989-03-01 | Midy Spa | Medicamenti a base di analoghi di feniletanolammine per il trattamento di disturbi gastro-intestinali ed uterini |
JP2837408B2 (ja) * | 1987-05-30 | 1998-12-16 | 鐘紡株式会社 | アクリル系繊維の処理方法 |
US5135955A (en) * | 1988-04-25 | 1992-08-04 | Eli Lilly And Company | Propanamine derivatives |
FI892341A (fi) * | 1988-06-10 | 1989-12-11 | Hoffmann La Roche | Propanolaminderivat. |
CA2023954C (fr) * | 1989-10-17 | 1999-05-04 | Hiroyuki Nohira | Procede de resolution optique de l'acide 2-(3-benzoyl) phenylpropionique |
US6031003A (en) * | 1991-08-23 | 2000-02-29 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
US6001884A (en) * | 1991-08-23 | 1999-12-14 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
US5763569A (en) * | 1991-08-23 | 1998-06-09 | The Brigham And Women's Hospital, Inc | Calcium receptor-active molecules |
US6313146B1 (en) | 1991-08-23 | 2001-11-06 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
US5688938A (en) * | 1991-08-23 | 1997-11-18 | The Brigham & Women's Hospital, Inc. | Calcium receptor-active molecules |
US5858684A (en) * | 1991-08-23 | 1999-01-12 | The Brigham And Women's Hospital, Inc. | Method of screening calcium receptor-active molecules |
US6011068A (en) * | 1991-08-23 | 2000-01-04 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
CA2115828C (fr) * | 1991-08-23 | 2011-09-20 | Edward F. Nemeth | Molecules actives pour la reception du calcium |
US5321036A (en) * | 1993-02-10 | 1994-06-14 | Bristol-Myers Squibb Company | Thiazole and oxazole-based β3 adrenergic receptor agonists |
US5962314A (en) * | 1993-02-23 | 1999-10-05 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
HU229474B1 (en) | 1994-10-21 | 2014-01-28 | Nps Pharma Inc | Calcium receptor-active compounds, pharmaceutical compositions containing them and use of the compositions |
ES2280460T3 (es) | 1996-05-01 | 2007-09-16 | Nps Pharmaceuticals, Inc. | Compuestos activos frente a receptores de iones inorganicos. |
US7321065B2 (en) * | 2003-04-18 | 2008-01-22 | The Regents Of The University Of California | Thyronamine derivatives and analogs and methods of use thereof |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL56308C (fr) * | 1941-03-15 | |||
GB1200886A (en) * | 1966-09-23 | 1970-08-05 | Allen & Hanburys Ltd | Phenylaminoethanol derivatives |
GB1301134A (en) | 1970-07-18 | 1972-12-29 | Pfizer Ltd | SUBSTITUTED 1-PHENYL-2-ALLYLAMINO-ALKANOLS, 1-PHENYL-2-ALLYLAMINO-ALKANES AND alpha-AMINOALKYLPHENYL KETONES |
BE788850A (fr) * | 1972-09-15 | 1973-03-15 | Hoffmann La Roche | Derives d'acide benzoique |
US4000192A (en) * | 1973-05-07 | 1976-12-28 | Allen & Hanburys Limited | Pharmacologically active compounds |
IE39247B1 (en) * | 1973-05-07 | 1978-08-30 | Allen & Hanburys Ltd | Substituted benzamides |
NZ190854A (en) * | 1978-06-28 | 1984-10-19 | Beecham Group Ltd | 2-hydroxy-2-phenyl ethylamine derivatives;pharmaceutical compositions |
IL57673A0 (en) * | 1978-07-03 | 1979-10-31 | Lilly Co Eli | Optically active phenethanolamines and method for increasing cardiac contractility |
-
1979
- 1979-06-26 DK DK268679A patent/DK160936C/da not_active IP Right Cessation
- 1979-06-26 DK DK268779A patent/DK268779A/da not_active Application Discontinuation
- 1979-06-26 IL IL57672A patent/IL57672A/xx unknown
- 1979-06-26 CA CA000330553A patent/CA1142954A/fr not_active Expired
- 1979-06-26 CA CA000330554A patent/CA1145767A/fr not_active Expired
- 1979-06-26 IL IL57671A patent/IL57671A/xx unknown
- 1979-06-27 NZ NZ190861A patent/NZ190861A/xx unknown
- 1979-06-27 PH PH22702A patent/PH14522A/en unknown
- 1979-06-27 PH PH22698A patent/PH15275A/en unknown
- 1979-06-27 EG EG387/78A patent/EG14238A/xx active
- 1979-06-27 NZ NZ190863A patent/NZ190863A/xx unknown
- 1979-06-28 PT PT69843A patent/PT69843A/pt unknown
- 1979-06-28 AU AU48487/79A patent/AU523720B2/en not_active Expired
- 1979-06-28 PT PT69839A patent/PT69839A/pt unknown
- 1979-06-28 AU AU48489/79A patent/AU523721B2/en not_active Ceased
- 1979-06-29 HU HU79EI867A patent/HU179171B/hu unknown
- 1979-06-29 FR FR7916993A patent/FR2430410B1/fr not_active Expired
- 1979-06-29 FR FR7916994A patent/FR2430411A1/fr active Granted
- 1979-06-29 HU HU79EI868A patent/HU179172B/hu not_active IP Right Cessation
- 1979-07-02 JP JP8489079A patent/JPS559096A/ja active Granted
- 1979-07-02 RO RO7998013A patent/RO77732A/fr unknown
- 1979-07-02 DE DE7979301278T patent/DE2964604D1/de not_active Expired
- 1979-07-02 RO RO7998009A patent/RO77728A/fr unknown
- 1979-07-02 EP EP79301279A patent/EP0007204B1/fr not_active Expired
- 1979-07-02 CS CS794632A patent/CS209815B2/cs unknown
- 1979-07-02 GB GB08135768A patent/GB2101582B/en not_active Expired
- 1979-07-02 BG BG045343A patent/BG31647A3/xx unknown
- 1979-07-02 SU SU792786202A patent/SU965350A3/ru active
- 1979-07-02 CS CS794631A patent/CS208664B2/cs unknown
- 1979-07-02 BE BE1/9445A patent/BE877394A/fr not_active IP Right Cessation
- 1979-07-02 GR GR59490A patent/GR72940B/el unknown
- 1979-07-02 GB GB7922952A patent/GB2028799B/en not_active Expired
- 1979-07-02 EP EP81109789A patent/EP0048037A1/fr not_active Ceased
- 1979-07-02 BE BE1/9444A patent/BE877393A/fr not_active IP Right Cessation
- 1979-07-02 BG BG044169A patent/BG31375A3/xx unknown
- 1979-07-02 DE DE7979301279T patent/DE2964091D1/de not_active Expired
- 1979-07-02 RO RO105064A patent/RO83051B/ro unknown
- 1979-07-02 FI FI792081A patent/FI792081A/fi not_active Application Discontinuation
- 1979-07-02 LU LU81457A patent/LU81457A1/fr unknown
- 1979-07-02 BG BG044166A patent/BG31645A3/xx unknown
- 1979-07-02 LU LU81458A patent/LU81458A1/fr unknown
- 1979-07-02 JP JP8489179A patent/JPS559097A/ja active Pending
- 1979-07-02 SU SU792782302A patent/SU849997A3/ru active
- 1979-07-02 GB GB7922955A patent/GB2028802B/en not_active Expired
- 1979-07-02 EP EP79301278A patent/EP0006766B1/fr not_active Expired
- 1979-07-02 FI FI792082A patent/FI792082A/fi not_active Application Discontinuation
- 1979-07-02 RO RO105065A patent/RO83052B/ro unknown
- 1979-07-02 CH CH616179A patent/CH642618A5/fr not_active IP Right Cessation
- 1979-07-02 CS CS794631A patent/CS208663B2/cs unknown
- 1979-07-02 CH CH616279A patent/CH643529A5/fr not_active IP Right Cessation
- 1979-07-02 CS CS794631A patent/CS208662B2/cs unknown
- 1979-07-02 GR GR59491A patent/GR74524B/el unknown
- 1979-07-02 BG BG045342A patent/BG31646A3/xx unknown
- 1979-07-03 ZA ZA793297A patent/ZA793297B/xx unknown
- 1979-07-03 AT AT0463679A patent/AT367025B/de not_active IP Right Cessation
- 1979-07-03 ZA ZA793296A patent/ZA793296B/xx unknown
- 1979-07-03 ES ES482155A patent/ES482155A1/es not_active Expired
- 1979-07-03 PL PL1979216814A patent/PL117551B1/pl unknown
- 1979-07-03 DD DD79214069A patent/DD144761A5/de unknown
- 1979-07-03 DD DD79214070A patent/DD144762A5/de unknown
- 1979-07-03 AR AR277167A patent/AR229080A1/es active
- 1979-07-03 AT AT0463579A patent/AT372937B/de not_active IP Right Cessation
- 1979-07-03 AR AR277166A patent/AR225744A1/es active
- 1979-07-03 PL PL1979216811A patent/PL121297B1/pl unknown
- 1979-07-03 ES ES482156A patent/ES482156A1/es not_active Expired
- 1979-07-03 PL PL1979226370A patent/PL117997B1/pl unknown
- 1979-07-03 PL PL1979226371A patent/PL117996B1/pl unknown
- 1979-08-08 IE IE1227/79A patent/IE48769B1/en not_active IP Right Cessation
- 1979-08-08 IE IE1228/79A patent/IE48586B1/en unknown
-
1980
- 1980-04-01 ES ES490215A patent/ES8104190A1/es not_active Expired
- 1980-04-01 ES ES490214A patent/ES8104189A1/es not_active Expired
- 1980-04-24 FR FR8009239A patent/FR2450806B1/fr not_active Expired
- 1980-08-13 SU SU802957757A patent/SU1007554A3/ru active
- 1980-08-13 SU SU802955864A patent/SU957761A3/ru active
- 1980-10-29 AR AR283051A patent/AR231434A1/es active
- 1980-10-29 AR AR283050A patent/AR227165A1/es active
-
1982
- 1982-02-12 KR KR8200619A patent/KR880002310B1/ko active
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