CN112755107A

CN112755107A - Preparation for treating impotence and premature ejaculation and preparation method thereof

Info

Publication number: CN112755107A
Application number: CN202110090074.9A
Authority: CN
Inventors: 高广志
Original assignee: Individual
Current assignee: Individual
Priority date: 2021-01-22
Filing date: 2021-01-22
Publication date: 2021-05-07

Abstract

The invention belongs to the technical field of Chinese herbal medicine preparations, and discloses a preparation for treating impotence and premature ejaculation and a preparation method thereof. The preparation is prepared by selecting radix Achyranthis bidentatae and rhizoma Dioscoreae as principal drugs; dogwood, poria cocos, eucommia ulmoides, polygala tenuifolia, schisandra chinensis, rhizoma acori graminei, fructus broussonetiae, fennel, morinda officinalis, cistanche and prepared rehmannia root are used as ministerial drugs; grinding fructus Lycii as adjuvant drug into powder, and mixing with fructus Jujubae and Mel to obtain honeyed pill. By regulating the whole body function of a user, the symptoms of vein and kidney tonifying spleen, essence and blood deficiency, heart and kidney deficiency, waist soreness and backache, tinnitus, dark wood, premature senility, spermatorrhea, impotence, pale tongue, pulse sinking, anorexia and the like are further achieved. The preparation has effects of regulating immunity for a long time and improving male sexual function. The preparation method of the preparation has simple process, can effectively fully release and exert the pharmaceutical ingredients, promotes the absorption of each ingredient, has no toxic or side effect, is safe and reliable, has no damage to the body function of a user, and is suitable for large-scale production.

Description

Preparation for treating impotence and premature ejaculation and preparation method thereof

Technical Field

The invention belongs to the technical field of Chinese herbal medicine preparations, and particularly relates to a preparation for treating impotence and premature ejaculation and a preparation method thereof.

Background

Erectile Dysfunction (ED) is defined as the persistent inability of the penis to achieve or sustain an erection to meet sexual life. ED can be classified into light, medium and heavy degrees according to its degree, while impotence is severe ED.

Due to the fact that people lack knowledge of ED, many ED patients are burdened with heavy thoughts, normal family life is affected, and the characters become isolated and easy to thrive, so that interpersonal relationship is affected. The causes of ED were considered to be related to the decrease in androgen levels, aging and psychological factors until the last 70 th century, and after the 70 th century, due to the progress of the research on erectile physiology and pathology, it was recognized that the psychological factors of consolidation can indeed cause ED, but for most men, ED is associated with many diseases (hypertension, diabetes, cardiovascular disease), drugs, trauma and surgery, etc., because the erectile mechanism is a complete hemodynamic process such as relaxation of the cavernous body smooth muscle of the penis, dilation of the penile artery, increase of blood flow and obstruction of venous return, during which the cause of dysfunction can be divided into psychogenic ED and organic ED.

Psychological ED refers to erectile dysfunction caused by psychosocial factors such as stress, depression, anxiety, and disharmony between couples. Organic ED can be divided into vascular, neurological, surgical and traumatic, mixed, and so on, due to different factors. Reasons for vascular nature: including any disease that may lead to reduced blood flow in the cavernous arteries of the penis, such as: atherosclerosis, arterial injury, arterial stenosis, pudendal artery bypass, cardiac dysfunction, etc., or penile vein leakage due to reduction of smooth muscle in the white membrane of penis and cavernous sinus of penis which obstruct the mechanism of venous return closure. The neurogenic cause is: erectile dysfunction can result from either central or peripheral nerve disease or injury. Surgery and trauma: great vessel surgery, radical prostate cancer surgery, radical abdominal-perineal rectal cancer surgery, pelvic fracture, lumbar vertebral compression fracture or straddling injury can cause blood vessel and nerve injury related to penis, resulting in erectile dysfunction. Endocrine disorders, chronic diseases and long-term use of certain drugs can also cause erectile dysfunction. The disease of penis itself: such as peyronie's disease, tortuosity, severe phimosis and balanitis. Mixed ED refers to erectile dysfunction caused by psychopsychological factors and organic diseases together. In addition, because organic ED is not treated in a timely manner, patients are stressed more mentally and fear failure of sexual intercourse, which makes ED treatment more complicated.

Premature ejaculation is one of the more common clinical male sexual dysfunction. Clinically, ejaculation is not caused when the penis erects and enters the vagina, and is diagnosed as premature ejaculation, but the ejaculation can be caused when the penis erects and enters the vagina for sexual intercourse, and the ejaculation within three minutes is considered to be the premature ejaculation.

Premature ejaculation means that after the penis erects, before the penis enters the vagina, or when the penis is just inserted into the vagina and before the penis is twitched, the penis already emits ejaculation, and the penis naturally gets soft and enters a refractory period. The etiology is complicated, and premature ejaculation is mostly related to mental factors, but some of them are caused by organic diseases, such as: premature ejaculation caused by prostatitis; some are caused by masturbation and excessive frequency. Premature ejaculation can induce impotence if the treatment is not timely.

The existing medicines for treating impotence and premature ejaculation have various varieties and are both Chinese and western patent medicines. However, the medicine for treating impotence and premature ejaculation has the disadvantages of slow effect, narrow applicable crowd range and inaccurate curative effect. The components of the sold medicine and western medicine are more, and the effect of radically curing impotence and premature ejaculation is not achieved.

Disclosure of Invention

In order to solve the problems in the prior art, the invention aims to provide a preparation for treating impotence and premature ejaculation and a preparation method thereof.

The technical scheme adopted by the invention is as follows: the preparation for treating impotence and premature ejaculation is mainly prepared from the following raw materials in parts by mass:

5-45 parts of achyranthes bidentata, 5-45 parts of Chinese yam, 3-30 parts of dogwood, 3-30 parts of poria cocos, 3-30 parts of eucommia ulmoides, 3-30 parts of polygala tenuifolia, 3-30 parts of schisandra chinensis, 3-30 parts of rhizoma acori graminei, 3-30 parts of fructus broussonetiae, 3-30 parts of fennel, 3-30 parts of morinda officinalis, 3-30 parts of cistanche, 3-30 parts of Chinese date, 2-15 parts of prepared rehmannia root and 2-15 parts of wolfberry fruit.

The invention provides a preparation for treating impotence and premature ejaculation, which is used for tonifying qi, activating blood and tonifying liver and kidney deficiency by selecting achyranthes root and Chinese yam as monarch drugs; dogwood, poria cocos, eucommia ulmoides, polygala tenuifolia, schisandra chinensis, rhizoma acori graminei, fructus broussonetiae, fennel, morinda officinalis, cistanche and prepared rehmannia root are used as ministerial drugs; fructus Lycii can be used as adjuvant drug to obtain final product. The honeyed pill is prepared by adding Mel into the preparation, and can be used for regulating the whole body function of user to achieve the effects of invigorating spleen, essence and blood deficiency, heart and kidney deficiency, waist soreness and backache, tinnitus, dark, senilism, spermatorrhea, sexual impotence, pale tongue, sunken pulse, anorexia, etc. The preparation has synergistic effect, and can regulate immunity for a long time and improve male sexual function.

Preferably, the preparation is mainly prepared from the following raw materials in parts by mass:

15-38 parts of achyranthes bidentata, 15-38 parts of Chinese yam, 10-25 parts of dogwood, 10-25 parts of poria cocos, 10-25 parts of eucommia ulmoides, 10-25 parts of polygala tenuifolia, 10-25 parts of schisandra chinensis, 10-25 parts of rhizoma acori graminei, 10-25 parts of fructus broussonetiae, 10-25 parts of fennel, 10-25 parts of morinda officinalis, 10-25 parts of cistanche, 10-25 parts of Chinese date, 5-13 parts of prepared rehmannia root and 5-13 parts of wolfberry fruit.

30 parts of achyranthes root, 30 parts of Chinese yam, 20 parts of dogwood, 20 parts of poria cocos, 20 parts of eucommia bark, 20 parts of polygala tenuifolia, 20 parts of schisandra chinensis, 20 parts of rhizoma acori graminei, 20 parts of paper mulberry fruit, 20 parts of fennel, 20 parts of morinda officinalis, 20 parts of cistanche, 20 parts of Chinese date, 10 parts of prepared rehmannia root and 10 parts of wolfberry fruit.

Achyranthes, also known as Nikko, the name Latin, AchyranthhesbidentaBlume, Amaranthaceae, achyranthes, perennial herb. The roots are used as the medicine, unprocessed, and activate blood and dredge channels; treating puerperal abdominal pain, menoxenia, amenorrhea, epistaxis, toothache due to deficiency fire, loempe and edema; for use in cooking, liver and kidney are tonified, waist and knee are strengthened; it is indicated for soreness and pain of waist and knees, liver and kidney deficiency, traumatic injury, blood stasis and pain. The veterinary drug is used for treating cattle foot softening disease, bone fracture due to falling injury, and the like. Bitter, sweet, sour and neutral in nature. Meridian tropism means that it enters liver and kidney meridians. Has the effects of removing blood stasis, dredging channels, nourishing liver and kidney, strengthening bones and muscles, inducing diuresis, treating stranguria and drawing blood downward. The main indications are amenorrhea, dysmenorrheal, soreness and pain of waist and knees, weakness of bones and muscles, stranguria, edema, headache, dizziness, toothache, skin ulcer, hematemesis and epistaxis.

Chinese yam, tuber is the traditional Chinese medicine 'Huaishan', tuber is rich in starch, can be used for vegetables and vegetables to eat; it can tonify spleen and stomach deficiency, and is used for treating qi deficiency, asthenia, dyspepsia, spermatorrhea, enuresis, and innominate toxic swelling. The root can be used as a medicine, is sweet, warm and mild and has no toxicity. It is mainly used for reinforcing deficiency and win-win, removing cold and heat evil, reinforcing middle warmer, benefiting strength, growing muscle and strengthening yin. It can be taken for a long time, and has effects of improving hearing and eyesight, reducing weight, and prolonging life. This meridian. The wind comes from the head and face, the head wind and eyes are dizzy, the qi is downward, the lumbago is stopped, the consumptive disease is treated and the emaciation is treated, the five internal organs are filled, and the dysphoria with smothery sensation is removed. And (6) recording. Tonify the five consumptive diseases and seven injuries, remove cold wind, calm the heart, tranquilize mind and tonify heart-qi deficiency.

Dogwood (scientific name: cornusffectialis sieb. et Zucc.) deciduous trees or shrubs. The jujube peel is commonly known as the jujube peel, is used for medicine, is sour and astringent in taste, is slightly warm in nature, is a astringing and strengthening medicine, and has the effects of tonifying the liver and the kidney and stopping sweating. The fruit drugs are used as astringent hematinic and tonic; it has effects in invigorating stomach, nourishing liver and kidney, and treating anemia, lumbago, neurasthenia, and heart failure. It is sour and astringent in nature and flavor, entering liver and kidney meridians. Astringing and astringing, has effects of nourishing liver and kidney, and invigorating kidney and arresting seminal emission, and is suitable for treating soreness of waist and knees, spermatorrhea, giddiness and tinnitus caused by liver and kidney deficiency.

Poria, tranquilizing, toxin-removing and anticancer. Mild property and mild action, and induce diuresis without damaging healthy qi. The proper amount of the health food can be taken as a good nursing product in spring and summer in wet seasons. Can be used for treating dysuria, edema, fullness, phlegm retention, cough, vomiting, diarrhea, spermatorrhea, stranguria with turbid urine, palpitation, and amnesia. The contained pachymic acid has effects of enhancing immunity, resisting tumor, tranquilizing mind, and lowering blood sugar. Can relax smooth muscle of digestive tract, inhibit gastric acid secretion, prevent hepatocyte necrosis, and resist bacteria.

Eucommia ulmoides, a medicinal eucommia ulmoides, is the dried bark of eucommia ulmoides of the family eucommia ulmoides, and is a rare and nourishing medicinal material in China. It is sweet in taste and warm in nature. Has effects in tonifying liver and kidney, strengthening muscle and bone, regulating Chong and ren meridians, and preventing miscarriage. Can be used for treating lumbago, leg pain, soreness, weakness, and asthenia due to kidney yang deficiency, and symptoms such as hypochondriac instability, and scrotum pruritus due to liver qi deficiency. It is listed as the superior in Shen nong Ben Cao Jing.

Polygala tenuifolia Willd, also known as \33917, WUTANG, 34112, 33964and so on. Producing northeast, northwest, central and Sichuan; perennial herbs, strong and strong taproots, and phloem flesh. Has effects in tranquilizing mind, improving intelligence, eliminating phlegm, and relieving swelling, and can be used for treating insomnia, dreaminess, amnesia, palpitation, absentmindedness, expectoration, skin sore, swelling and toxin, and breast swelling and pain caused by imbalance between heart-yang and kidney-yin.

Schisandra chinensis (school name: Schisandra chinensis (Turcz.) Baill) is dried mature fruit of Schisandra chinensis (Schisandra chinensis, Magnoliaceae) or Schisandra chinensis (Schisandra chinensis, et al, Wils. Has the effects of nourishing and strengthening body, has high medicinal value, and has the effect of strengthening body, and can be used together with Qiongzhen Ganoderma for treating insomnia.

Acorus gramineus (Latin scientific name: Acorustataranovii), belongs to Araceae, Acorus gramineus and perennial grass-like plants.

Broussonetia papyrifera, fruit of Broussonetia papyrifera, can be used as medicine. Nourish kidney, clear liver and improve vision. It is indicated for consumptive disease, blurred vision, nebula, edema of damp-heat.

Fennel, the main ingredient contained is fennel oil, can stimulate gastrointestinal nerve and blood vessels, promote secretion of digestive juice, increase gastrointestinal peristalsis, eliminate accumulated gas, so have the efficacy of invigorating stomach, promoting qi circulation; sometimes, the gastrointestinal motility is reduced after excitation, thereby helping to relieve spasm and pain.

Morinda officinalis, (academic name: Morinda officinalis how.

Cistanchis herba (Cistanchedesericola Ma), also known as Cistanchis herba, Cistanchis herba and Cistanchis herba. Tonifying kidney yang; replenishing essence and blood; moistening intestinal tract. Deficiency of both the major and kidney yang; impotence due to deficiency of essence and blood; spermatorrhea; white turbidity; frequent micturition and dribbling; lumbago and weak feet; tinnitus and blurred vision; menstrual period of menstruation; infertility due to cold uterus; constipation due to intestinal dryness.

The cyclic adenosine monophosphate contained in the Chinese dates is an essential component for energy metabolism of human cells, can enhance muscle strength, eliminate fatigue, dilate blood vessels, increase myocardial contractility and improve myocardial nutrition, and has good effects of preventing and treating cardiovascular system diseases.

Prepared rehmannia root, named as Chinese medicinal material, has the main functions of nourishing yin and enriching blood. It is indicated for deficiency of yin and blood, atrophy and weakness of waist and knees, fatigue, cough, steaming bone, seminal emission, metrorrhagia, menoxenia, diabetes, scanty urine, deafness and blurred vision.

Fructus Lycii is mature fruit of Lycium barbarum L of Solanaceae. The lycium barbarum polysaccharide can increase the serum sex hormone level of a rat with damaged testis; increase the organ coefficient of testis and epididymis, improve the SOD activity of rat testis tissue, reduce the content of malondialdehyde, and restore the damaged testis tissue to be close to normal level.

Preferably, the formulation is an oral formulation.

A preparation method of a preparation for treating impotence and premature ejaculation comprises selecting achyranthes bidentata, Chinese yam, dogwood, poria cocos, eucommia ulmoides, polygala tenuifolia, schisandra chinensis, acorus gramineus soland, fructus broussonetiae, fennel, morinda officinalis, cistanche deserticola, prepared rehmannia root and wolfberry fruit according to corresponding proportions, mixing, crushing, filtering, and adding a solidifying agent to obtain a standby product A; mixing fructus Jujubae and the extract A to obtain the final product.

Preferably, the particle size of the powder after the pulverization is 200-400 meshes.

Preferably, the solid agent is honey.

The above solidifying agent is prepared by heating Mel to above 119 deg.C, evaporating water to obtain reddish brown bubbles with luster, twisting, and sticking, and drawing white thread. The purpose of refining honey is to remove impurities, destroy enzymes, kill microorganisms, evaporate water and enhance viscosity.

Preferably, the mass ratio of the solid agent to the total mass of achyranthes root, Chinese yam, dogwood, tuckahoe, eucommia bark, polygala root, schisandra fruit, grassleaf sweelflag rhizome, paper mulberry fruit, common fennel fruit, morinda root, desertliving cistanche, prepared rehmannia root and medlar is 2-3: 1.

Preferably, the Chinese date and the spare A are uniformly mixed for 30 to 50 minutes;

the mixing method comprises coating fructus Jujubae with the material A and/or removing core of fructus Jujubae, and filling the material A.

Preferably, the finished product is a pill.

The invention has the beneficial effects that:

the invention provides a preparation for treating impotence and premature ejaculation, which is used for tonifying qi, activating blood and tonifying liver and kidney deficiency by selecting achyranthes root and Chinese yam as monarch drugs; dogwood, poria cocos, eucommia ulmoides, polygala tenuifolia, schisandra chinensis, rhizoma acori graminei, fructus broussonetiae, fennel, morinda officinalis, cistanche and prepared rehmannia root are used as ministerial drugs; grinding fructus Lycii as adjuvant drug into powder, and mixing with fructus Jujubae and Mel to obtain honeyed pill. The honeyed pill can regulate the whole body function of the user, and can reach the symptoms of invigorating spleen, essence and blood deficiency, heart and kidney deficiency, soreness of waist, backache, tinnitus, premature senility, spermatorrhea, impotence, sunken pulse, anorexia, etc. The preparation has synergistic effect, and can regulate immunity for a long time and improve male sexual function. The preparation method of the preparation has simple process, can effectively fully release and exert the pharmaceutical ingredients, promotes the absorption of each ingredient, has no toxic or side effect, is safe and reliable, has no damage to the body function of a user, and is suitable for large-scale production.

Detailed Description

The present invention is further illustrated below with reference to specific examples. It will be appreciated by those skilled in the art that the following examples, which are set forth to illustrate the present invention, are intended to be part of the present invention, but not to be construed as limiting the scope of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention. The examples were carried out under the conventional conditions, unless otherwise specified. The reagents used are all conventional products which are commercially available.

Example 1:

a preparation method of a preparation for treating impotence and premature ejaculation comprises selecting 50 g of achyranthes bidentata, 50 g of Chinese yam, 30 g of dogwood, 30 g of tuckahoe, 30 g of eucommia bark, 30 g of polygala tenuifolia, 30 g of schisandra chinensis, 30 g of rhizoma acori graminei, 30 g of fructus broussonetiae, 30 g of fennel, 30 g of morinda officinalis, 30 g of cistanche, 20 g of prepared rehmannia root and 20 g of medlar according to corresponding proportion, mixing and crushing, filtering to obtain powder with the particle size of 200 meshes, and adding 940 g of honey to obtain a spare substance A; coating 30 g of Chinese date with the standby product A, and uniformly mixing for 30 minutes to obtain the finished product pills.

Example 2:

a preparation method of a preparation for treating impotence and premature ejaculation comprises selecting 50 g of achyranthes bidentata, 50 g of Chinese yam, 30 g of dogwood, 30 g of tuckahoe, 30 g of eucommia bark, 30 g of polygala tenuifolia, 30 g of schisandra chinensis, 30 g of rhizoma acori graminei, 30 g of fructus broussonetiae, 30 g of fennel, 30 g of morinda officinalis, 30 g of cistanche, 20 g of prepared rehmannia root and 20 g of medlar according to a corresponding proportion, mixing and crushing the mixture, filtering the powder to obtain 400 meshes of particle size, and adding 1410 g of honey to obtain a spare substance A; after 30 g of Chinese date is denucleated, the standby substance A is filled into the Chinese date to obtain the finished product pills.

Example 3:

a preparation method of a preparation for treating impotence and premature ejaculation comprises selecting 45 g of achyranthes bidentata, 45 g of Chinese yam, 30 g of dogwood, 30 g of tuckahoe, 30 g of eucommia bark, 30 g of polygala tenuifolia, 30 g of schisandra chinensis, 30 g of rhizoma acori graminei, 30 g of fructus broussonetiae, 30 g of fennel, 30 g of morinda officinalis, 30 g of cistanche, 15 g of prepared rehmannia root and 15 g of medlar according to corresponding proportion, mixing and crushing the mixture, filtering the powder to obtain 200 meshes of particle size, and adding 900 g of honey to obtain a spare substance A; coating 30 g of Chinese date with the standby product A, and uniformly mixing for 50 minutes to obtain the finished product pills.

Example 4:

a preparation method of a preparation for treating impotence and premature ejaculation comprises selecting 45 g of achyranthes bidentata, 45 g of Chinese yam, 30 g of dogwood, 30 g of tuckahoe, 30 g of eucommia bark, 30 g of polygala tenuifolia, 30 g of schisandra chinensis, 30 g of rhizoma acori graminei, 30 g of fructus broussonetiae, 30 g of fennel, 30 g of morinda officinalis, 30 g of cistanche, 15 g of prepared rehmannia root and 15 g of medlar according to corresponding proportion, mixing and crushing the mixture, filtering the mixture to obtain powder with the particle size of 400 meshes, and adding 1350 g of honey to obtain a spare substance A; filling the material A into fructus Jujubae to obtain pill.

Example 5:

a preparation method of a preparation for treating impotence and premature ejaculation comprises selecting 15 g of achyranthes bidentata, 15 g of Chinese yam, 10 g of dogwood, 10 g of tuckahoe, 10 g of eucommia ulmoides, 10 g of polygala tenuifolia, 10 g of schisandra chinensis, 10 g of rhizoma acori graminei, 10 g of fructus broussonetiae, 10 g of fennel, 10 g of morinda officinalis, 10 g of cistanche, 5 g of prepared rehmannia root and 5 g of medlar according to corresponding proportion, mixing and crushing, filtering to obtain powder with the particle size of 200 meshes, and adding 300 g of honey to obtain a spare substance A; coating 10 g of Chinese date with the standby material A, and uniformly mixing for 30 minutes to obtain the finished product pills.

Example 6:

a preparation method of a preparation for treating impotence and premature ejaculation comprises selecting 15 g of achyranthes bidentata, 15 g of Chinese yam, 10 g of dogwood, 10 g of tuckahoe, 10 g of eucommia ulmoides, 10 g of polygala tenuifolia, 10 g of schisandra chinensis, 10 g of rhizoma acori graminei, 10 g of fructus broussonetiae, 10 g of fennel, 10 g of morinda officinalis, 10 g of cistanche, 5 g of prepared rehmannia root and 5 g of medlar according to corresponding proportion, mixing and crushing the mixture, filtering the powder to obtain 400 meshes of particle size, and adding 450 g of honey to obtain a spare substance A; coating 10 g of Chinese date with the standby material A, and uniformly mixing for 50 minutes to obtain the finished product pills.

Example 7:

a preparation method for a preparation for treating impotence and premature ejaculation comprises selecting 38 g of achyranthes bidentata, 38 g of Chinese yam, 25 g of dogwood, 25 g of tuckahoe, 25 g of eucommia bark, 25 g of polygala tenuifolia, 25 g of schisandra chinensis, 25 g of rhizoma acori graminei, 25 g of fructus broussonetiae, 25 g of fennel, 25 g of morinda officinalis, 25 g of cistanche, 13 g of prepared rehmannia root and 13 g of medlar according to a corresponding proportion, mixing and crushing the mixture, filtering the powder to obtain 200 meshes of particle size, and adding 754 g of honey to obtain a spare substance A; filling the material A into fructus Jujubae to obtain pill.

Example 8:

a preparation method for a preparation for treating impotence and premature ejaculation comprises selecting 38 g of achyranthes bidentata, 38 g of Chinese yam, 25 g of dogwood, 25 g of tuckahoe, 25 g of eucommia bark, 25 g of polygala tenuifolia, 25 g of schisandra chinensis, 25 g of rhizoma acori graminei, 25 g of fructus broussonetiae, 25 g of fennel, 25 g of morinda officinalis, 25 g of cistanche, 13 g of prepared rehmannia root and 13 g of medlar according to corresponding proportion, mixing and crushing the mixture, filtering the mixture to obtain powder with the particle size of 400 meshes, and adding 1131 g of honey to obtain a spare substance A; filling the material A into fructus Jujubae to obtain pill.

Example 9:

a preparation method for a preparation for treating impotence and premature ejaculation comprises selecting 30 g of achyranthes bidentata, 30 g of Chinese yam, 20 g of dogwood, 20 g of tuckahoe, 20 g of eucommia ulmoides, 20 g of polygala tenuifolia, 20 g of schisandra chinensis, 20 g of rhizoma acori graminei, 20 g of fructus broussonetiae, 20 g of fennel, 20 g of morinda officinalis, 20 g of cistanche, 10 g of prepared rehmannia root and 10 g of medlar according to a corresponding proportion, mixing and crushing the mixture, filtering the powder to obtain 200 meshes of particle size, and adding 600 g of honey to obtain a spare substance A; filling the material A into fructus Jujubae to obtain pill.

Example 10:

a preparation method for a preparation for treating impotence and premature ejaculation comprises selecting 30 g of achyranthes bidentata, 30 g of Chinese yam, 20 g of dogwood, 20 g of tuckahoe, 20 g of eucommia ulmoides, 20 g of polygala tenuifolia, 20 g of schisandra chinensis, 20 g of rhizoma acori graminei, 20 g of fructus broussonetiae, 20 g of fennel, 20 g of morinda officinalis, 20 g of cistanche, 10 g of prepared rehmannia root and 10 g of medlar according to a corresponding proportion, mixing and crushing the mixture, filtering the powder to obtain 400 meshes of particle size, and adding 900 g of honey to obtain a spare substance A; coating 20 g of Chinese date with the standby product A, and uniformly mixing for 50 minutes to obtain the finished product pill.

In the actual operation process of all the embodiments, the selected blending device comprises a three-dimensional motion mixer, stainless steel materials with specification models of SYH-30 and SYH-1000, and manufacturers: jiangyin and Rong mechanical Co. The selection of the stirring device is not limited to the above, and all devices which can complete the corresponding stirring work and have no influence on raw materials belong to the protection scope of the invention.

In the practical operation process of all the above embodiments, the selected filtering device comprises a microporous membrane filter, a stainless steel material, and the style: tubular, manufacturer: sitepu filtration equipment, Inc., New county. The selection of the filtering device is not limited to the above, and all devices which can complete the corresponding filtering work and have no influence on raw materials belong to the protection scope of the invention.

In the actual operation process of all the embodiments, the selected pulverizer is a Chinese herbal medicine superfine pulverizer, and the type is as follows: JCWF-15A, manufacturer: junchen distance mechanical equipment, Inc. The selection of the type of the pulverizer and the selection of manufacturers can be set according to the actual environment and the actual requirements in the specific implementation process. All the raw materials can be crushed, and the components of the crushed materials are consistent with those of the finished products obtained in the above embodiments after being filtered and sieved, and the method belongs to the protection scope of the invention.

In the practical operation process, the finished product needs to be packaged, and a horizontal packaging machine and an ink-jet printer are respectively selected. The horizontal packaging machine is made of stainless steel, the specification and model are SG-180, and a manufacturer: shanghai plastic packaging science and technology, Inc. The ink jet numbering machine is made of stainless steel, the specification and model are V803-D, and a manufacturer: beijing Oriental Union technologies, Inc.

The pellets prepared in the above examples are recommended to be 0.5 to 0.8 g.

The administration mode is as follows: orally taking 5 pills at a time, 3 times a day, 15 days as a treatment course, and 3 treatment courses in total; other related medicines and other treatments are stopped taking during the taking period.

Examples of the experiments

Subject: randomly selecting patients with symptoms of impotence, premature ejaculation, dizziness, amnesia, drowsiness, weakness, soreness of waist and knees as experimental subjects, and selecting 110 patients with age of 35-85 years.

10 patients selected from the group were used as Viagra as a control group; the remaining 100 patients were used as experimental groups, 10 subjects per group were divided into 10 groups, and numbered: 1-10.

The experimental reagent and the using method are as follows: the finished preparation corresponding to each example is prepared according to the configuration mode of the preparation provided in each example. The finished preparation prepared in each example is orally taken by each group of experimental subjects, 5 pills are taken at a time, 3 times a day and 15 days are taken as a treatment course, and 3 treatment courses are totally treated.

Control group took viagra orally 3 times daily, 3 capsules each time. The symptoms of the experimental group and the control group after one treatment course of administration of the corresponding products were observed separately.

Diagnostic criteria: the penis can not erect or erect and can not complete the intercourse.

Other related medicines and other treatments are stopped taking during the taking period.

The judgment standard of the curative effect is as follows:

made according to the first edition of clinical research guidelines for new drugs in Chinese medicine (1993).

And (3) curing: the treatment lasts for 1 month, the penile erection is more than 90 degrees, and 75 percent of intercourse chances can be successful;

the effect is shown: after treatment, the erection is more than 90 degrees, and 50 percent of intercourse chances can be successful;

the method has the following advantages: after treatment, the erection is improved, and over 25 percent of intercourse chance can be successfully treated;

and (4) invalidation: all indexes before and after the administration are not improved.

The experimental results are as follows:

the data result shows that the cure rate of the invention in the example 9 and the example 10 reaches 90%. The cure rate of other examples is above 50%. Meanwhile, after the experimental treatment course is finished, the experimental subjects of the experimental group do not have any discomfort phenomenon and relapse condition. In the control group, some subjects had recurrence.

Clinical data:

patient 1: male, age 35.

The diseased condition is: it is diagnosed as impotence and premature ejaculation.

The treatment results are as follows: is orally administered in 5 pills each time, 3 times a day, and 15 days as a treatment course for 5 treatment courses. The medicine is stopped for 1 week after the treatment is finished, and then the medicine is cured after being continuously taken for 1 treatment course.

While particular embodiments of the present invention have been illustrated and described, it will be appreciated that the present invention is not limited to the above-described alternative embodiments, and that various other forms of product may be devised by anyone in light of the present invention. The foregoing detailed description should not be construed as limiting the scope of the invention, and it will be understood by those skilled in the art that modifications may be made to the technical solutions described in the foregoing embodiments, or that equivalent substitutions may be made to some or all of the technical features thereof, without departing from the spirit and scope of the invention, and that these modifications or substitutions may not substantially depart from the essence of the corresponding technical solutions.

Claims

1. The preparation for treating impotence and premature ejaculation is characterized by being prepared from the following raw materials in parts by mass:

2. The preparation for treating impotence and premature ejaculation as claimed in claim 1, wherein the preparation is prepared from the following raw materials in parts by mass:

3. The preparation for treating impotence and premature ejaculation as claimed in claim 2, wherein the preparation is prepared from the following raw materials in parts by mass:

4. The preparation for treating impotence and premature ejaculation as claimed in any one of claims 1 to 3, wherein the preparation is an oral preparation.

5. The method for preparing a preparation for treating impotence and premature ejaculation as claimed in any one of claims 1 to 3, wherein the preparation method comprises selecting Achyranthis radix, rhizoma Dioscoreae, Corni fructus, Poria, Eucommiae cortex, cortex et radix Polygalae, fructus Schisandrae chinensis, rhizoma Acori Graminei, fructus Broussonetiae, fructus Foeniculi, radix Morindae officinalis, Cistanchis herba, radix rehmanniae Preparata and fructus Lycii according to the corresponding ratio, mixing and pulverizing, adding a solidifying agent to obtain a stock A; mixing fructus Jujubae and the extract A to obtain the final product.

6. The method for preparing a preparation for treating impotence and premature ejaculation as claimed in claim 5, wherein the particle size of the pulverized powder is 200-400 mesh.

7. The method for preparing a preparation for treating impotence and premature ejaculation as claimed in claim 5, wherein the solid agent is honey.

8. The method of claim 5, wherein the mass ratio of the solidifying agent to the total mass of achyranthes bidentata, yam, cornus officinalis, poria cocos, eucommia ulmoides, polygala tenuifolia, schisandra chinensis, acorus gramineus soland, broussonetia papyrifera, fennel, morinda officinalis, cistanche deserticola, prepared rehmannia roots and wolfberry fruits is 2-3: 1.

9. The method for preparing a preparation for treating impotence and premature ejaculation as claimed in claim 5, wherein the fructus Jujubae is mixed with the stock A for 30-50 min;

10. The method for preparing a preparation for treating impotence and premature ejaculation as claimed in claim 5, wherein the final product is a pill.