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CN103520621B - A kind of Chinese medicine composition for the treatment of senile cataract and preparation method thereof - Google Patents

A kind of Chinese medicine composition for the treatment of senile cataract and preparation method thereof Download PDF

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CN103520621B
CN103520621B CN201310509764.9A CN201310509764A CN103520621B CN 103520621 B CN103520621 B CN 103520621B CN 201310509764 A CN201310509764 A CN 201310509764A CN 103520621 B CN103520621 B CN 103520621B
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曾庆芸
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Zeng Qingyun
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Abstract

The invention discloses a kind of Chinese medicine composition for the treatment of senile cataract, in Chinese medicine composition, various crude drug is: Semen Persicae, Flos Carthami, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Rehmanniae Preparata, the Radix Paeoniae Alba, Fructus Atriplicis Sibiricae, Semen Cassiae, Fructus Lycii, Massa Medicata Fermentata, Radix Salviae Miltiorrhizae, Fructus Alpiniae Oxyphyllae, Fructus Mori, Fructus Ligustri Lucidi, Flos Chrysanthemi, Rhizoma Dioscoreae, Sargassum, Fructus Schisandrae Chinensis, Endothelium Corneum Gigeriae Galli, Pericarpium Citri Reticulatae, Magnetitum, Semen Celosiae, Rhizoma Seu Herba Bergeniae, shellfish tooth, Flos Eriocauli, Faeces Vespertilionis.The present invention has soothing liver and strengthening spleen, tonneau Xuan Fu, hard masses softening and resolving, or blood circulation promoting and blood stasis dispelling, changes tired sensible, improves microcirculation, be used for the treatment of various senile cataract; And processing technology is easy, the little and convenient drug administration of toxic and side effects, medicament is easy to manufacture, new drug with low cost.The through focus of energy, healing time is short, not easily recurs after healing.

Description

A kind of Chinese medicine composition for the treatment of senile cataract and preparation method thereof
Technical field
The present invention relates to the medicinal preparation containing deriving from plant, animal or raw mineral materials, particularly a kind of Chinese medicine composition for the treatment of senile cataract and preparation method thereof.
Background technology
Senile cataract is modal cataract, and after being more common in 50 years old, sickness rate increases with the growth at age.Senile cataract is the degenerative change engendered in lens ages process, and mechanism also imperfectly understands.Generally be divided into cortex, nuclearity and capsule mo(u)ld bottom half three kinds of multiple colonies to be more common in the middle-aged and elderly people of more than 50 years old, increase its sickness rate with the age and raise.Disease symptoms: with oculogyral shade at the moment, gradual Silent Neuritis visual deterioration, monocular diplopia or look more, iridization, photophobia and dazzle.Eyes are ill, and have successively, the order of severity differs.
Names of disease of tcm there is no cataractous name, mainly cataract, sees " Long Mu's Secret Treatise on Ophthalmology ".Namely Rhizoma Polygonati (crystalline lens) muddy pathological changes is referred to.Cataract quite up to the present.Successive dynasties doctor nationality is because of its cause of disease, shape, color, and degree is different and have many titles, as: fetal toxicosis cataract, incipient cataract, complicated cataract, as silver barrier, cataract etc.Its Symptoms is: when just suffering from, common fly flyings are sent out at the moment, and hang down and play, Haze mist, increases the weight of gradually, superficial, gradually blind.Outward appearance no abnormality seen, does not distinguish personage, only sees three light.Thoroughly see in pupil, Rhizoma Polygonati is the muddiness of different shape and color, Se Bai or micro-Huang, or pale blue, shape as star, as Flos Jujubae, as first quarter moon, as sword ridge, as the walking of hydrargyrum, as cream fat liquid, as in the dripping of oil, freezing in cup as ice.A lore can suffer from, also have eyes with sick.Duo Xia is worn with age, both liver and kidney deficiency, asthenia of essence and blood, or insufficiency of the spleen mistake fortune, and vital essence can not caused by sending nutrient upward to eye or the congestion that causes thus.In addition, stagnated heat of liver channel or the deficiency of YIN hold under the arm damp and hot on attack, also can cause primary disease.Clinical diagnosis: cataract without congestion and swelling pain, only conscious looks thing micro-dusk from the beginning of, eye, or the point-like having position fixing at the moment, strip or discoid shade; Or look near still clear, dim depending on dusk far away; Or dusk is looked in daylight, dark place is looked clearly; Or daylight is looked clearly, dusk is looked in dark place; Or look light, bright moon if any several.Dusk enters dim day, then gradually to not distinguishing personage, only seeing manually, even only depositing light sensation.Inspect pupil god, rounding is intact, and companding freely.From the beginning of, if brilliant pearl muddiness comes across edge, shape is as Flos Jujubae, sawtooth, and vision has no significant effect more.Continue the then greyish white swelling of brilliant pearl, and as oils and fats is bubbled through the water column, torch side photograph, the shade of visible yellow core is crescently be projeced into brilliant bead surface.Final mature cataract, the white rounding of color, torch side photograph, yellow core shade disappears.Now nebula hinders always surely, just should operative treatment.Otherwise with the passing of time brilliant pearl reduces, nebula like icicle and sinking.If brilliant pearl is muddy from core, gradually spread towards periphery, its color mostly is pale brown, reddish brown or black.Therapeutic Principle: primary disease is treated, soothing liver and strengthening spleen, tonneau Xuan Fu, hard masses softening and resolving, blood circulation promoting and blood stasis dispelling, coordinates the method treatments such as acupuncture, laser, external treatment.
Modern medicine is thought, the senile cataract cause of disease is comparatively complicated, may be that the many factors such as environment, nutrition, metabolism and heredity are to the result of crystalline lens comprehensive and long-term action.It is generally acknowledged that Oxidation causes cataractous earliest period to change.Ultraviolet radiation too much, drinking too much, smoking is many, women 's fertility is many, cardiovascular disease, hypertension, psychosis, body wound etc. are relevant with cataractous formation.Pathogenesis: it is generally acknowledged, radical damage causes the various common pathway causing the effect of cataract factor, and lens epithelial cells excessive Apoptosis and crystallin damage are also the key factors in cataract mechanism.In senile cataract forming process, main generation two kinds of pathological changes.The first, cortex of lens water-electrolyte balance is lacked of proper care, and causes moisture accumulation in crystalline lens, causes lens fibers edema, liquefaction.The second, the albuminous degeneration of nucleus lentis, swelling.These changes cause the lens fibers structure of proper alignment to get muddled.
Treatment is taked more 1, Drug therapy: there is no curative effect medicine certainly at present and be used for the treatment of cataract.Some early cataracts, sick lazy development of may slowing down after medication, vision also slightly improves, but the result of this not necessarily Drug therapy, advancing to maturation in early days because cataractous is a veryer long process, and it likely naturally stops at a certain developmental stage and is unlikely to have a strong impact on vision.Some in mid-term cataract patient, after medication, vision and lenticular opacity degree are not all improved.The cataract in nearly period of maturation, Drug therapy is more without practical significance.Not lower tens kinds conventional clinically at present of medicine, has collyrium or oral Chinese medicine and western medicine, but does not all have definite therapeutic effect.2, operative treatment: during because of cataract affected work and daily life, can operative treatment be considered.Current cataract operation mainly comprises: intracapsular extraction of cataract, extracapsular extraction of cataract+intraocular lens implants, cataract phacoemulsification art+intraocular lens implants, Laser sensor Cataract+intraocular lens implants, and the most frequently used modus operandi is cataract phacoemulsification art+intraocular lens implants.After extractio intracapsularis, patient can join frame eyeglasses or corneal contact lens by testing, or improves vision by cornea refractive surgery.
Summary of the invention
Technical problem to be solved by this invention is, provides that a kind of formula is simple, processing technology is easy, and the little and convenient drug administration of toxic and side effects, medicament is easy to manufacture, new drug with low cost.The present invention adopts the Chinese crude drug of different properties, has carried out scientific compatibility, can reach desirable therapeutic effect, and safety, toxic and side effects is little, and preparation is simple, and focus of going directly, healing time is short, not easily recurs after healing.
For solving the problems of the technologies described above, the invention provides a kind of Chinese medicine composition for the treatment of senile cataract, in described Chinese medicine composition, the ratio of weight and number of various crude drug is: 10 ~ 25 parts, Semen Persicae, 10 ~ 25 parts, Flos Carthami, Radix Angelicae Sinensis 10 ~ 25 parts, Rhizoma Chuanxiong 10 ~ 25 parts, 10 ~ 25 parts, Radix Rehmanniae Preparata, the Radix Paeoniae Alba 10 ~ 25 parts, Fructus Atriplicis Sibiricae 10 ~ 20 parts, Semen Cassiae 10 ~ 20 parts, Fructus Lycii 10 ~ 25 parts, Massa Medicata Fermentata 10 ~ 25 parts, Radix Salviae Miltiorrhizae 10 ~ 25 parts, Fructus Alpiniae Oxyphyllae 10 ~ 25 parts, Fructus Mori 10 ~ 25 parts, Fructus Ligustri Lucidi 10 ~ 25 parts, Flos Chrysanthemi 10 ~ 20 parts, Rhizoma Dioscoreae 10 ~ 20 parts, Sargassum 10 ~ 20 parts, Fructus Schisandrae Chinensis 10 ~ 25 parts, Endothelium Corneum Gigeriae Galli 10 ~ 20 parts, Pericarpium Citri Reticulatae 10 ~ 25 parts, Magnetitum 10 ~ 30 parts, Semen Celosiae 10 ~ 20 parts, Rhizoma Seu Herba Bergeniae 10 ~ 20 parts, 10 ~ 20 parts, shellfish tooth, Flos Eriocauli 10 ~ 20 parts and Faeces Vespertilionis 10 ~ 20 parts.
The Chinese medicine composition of described treatment senile cataract, the ratio of weight and number of various crude drug can also be: 10 ~ 25 parts, Semen Persicae, 15 ~ 25 parts, Flos Carthami, Radix Angelicae Sinensis 10 ~ 25 parts, Rhizoma Chuanxiong 20 ~ 25 parts, 15 ~ 25 parts, Radix Rehmanniae Preparata, the Radix Paeoniae Alba 10 ~ 25 parts, Fructus Atriplicis Sibiricae 10 ~ 20 parts, Semen Cassiae 10 ~ 20 parts, Fructus Lycii 20 ~ 25 parts, Massa Medicata Fermentata 20 ~ 25 parts, Radix Salviae Miltiorrhizae 10 ~ 25 parts, Fructus Alpiniae Oxyphyllae 10 ~ 15 parts, Fructus Mori 10 ~ 20 parts, Fructus Ligustri Lucidi 10 ~ 20 parts, Flos Chrysanthemi 10 ~ 20 parts, Rhizoma Dioscoreae 10 ~ 15 parts, Sargassum 10 ~ 15 parts, Fructus Schisandrae Chinensis 10 ~ 20 parts, Endothelium Corneum Gigeriae Galli 10 ~ 15 parts, Pericarpium Citri Reticulatae 10 ~ 15 parts, Magnetitum 10 ~ 20 parts, Semen Celosiae 15 ~ 20 parts, Rhizoma Seu Herba Bergeniae 10 ~ 20 parts, 10 ~ 20 parts, shellfish tooth, Flos Eriocauli 10 ~ 15 parts and Faeces Vespertilionis 10 ~ 20 parts.
The Chinese medicine composition of described treatment senile cataract, the ratio of weight and number of various crude drug also can be: 10 ~ 20 parts, Semen Persicae, 10 ~ 15 parts, Flos Carthami, Radix Angelicae Sinensis 10 ~ 20 parts, Rhizoma Chuanxiong 10 ~ 20 parts, 10 ~ 20 parts, Radix Rehmanniae Preparata, the Radix Paeoniae Alba 10 ~ 15 parts, Fructus Atriplicis Sibiricae 10 ~ 15 parts, Semen Cassiae 10 ~ 15 parts, Fructus Lycii 10 ~ 20 parts, Massa Medicata Fermentata 10 ~ 20 parts, Radix Salviae Miltiorrhizae 10 ~ 20 parts, Fructus Alpiniae Oxyphyllae 10 ~ 25 parts, Fructus Mori 20 ~ 25 parts, Fructus Ligustri Lucidi 10 ~ 25 parts, Flos Chrysanthemi 10 ~ 15 parts, Rhizoma Dioscoreae 10 ~ 20 parts, Sargassum 10 ~ 20 parts, Fructus Schisandrae Chinensis 20 ~ 25 parts, Endothelium Corneum Gigeriae Galli 15 ~ 20 parts, Pericarpium Citri Reticulatae 15 ~ 25 parts, Magnetitum 20 ~ 30 parts, Semen Celosiae 10 ~ 20 parts, Rhizoma Seu Herba Bergeniae 10 ~ 15 parts, 10 ~ 15 parts, shellfish tooth, Flos Eriocauli 10 ~ 20 parts and Faeces Vespertilionis 10 ~ 15 parts.
For solving the problems of the technologies described above, the present invention also provides a kind of preparation method for the treatment of the Chinese medicine composition of senile cataract, the dosage form of described Chinese medicine composition is cold compress agent, described preparation process is: first the described crude drug except Borneolum Syntheticum is ground into coarse powder, pulverize further again, cross 120 mesh sieves, collect and obtain fine powder a by the fine powder of 120 mesh sieves; Again the coarse powder not by 120 mesh sieves is dropped into multi-function extractor and extract twice, first time adds 4-6 times amount soak by water 1-2 hour, and second time adds 3-5 times amount soak by water 1-2 hour, merges twice decocting liquid, filters to get filtrate; Filtrate heating is concentrated into pasty state, puts into after 80 DEG C, baking oven is dried and cool, grind to form fine powder b, for subsequent use after fine powder a is mixed with fine powder b; Then by Borneolum Syntheticum extraction by steam distillation, crystal c is obtained; Added by crystal c in the mixture of fine powder a and fine powder b, mixing adds qs glycerin, glycerol addition be the 2-8 of fine powder mixture gross mass doubly, furnishing paste, loads in colored bottle after sterilization, and it is for subsequent use to put into refrigerator-freezer 0 DEG C-4 DEG C storage.
For solving the problems of the technologies described above, the present invention also provides a kind of preparation method for the treatment of the Chinese medicine composition of senile cataract, and the dosage form of described Chinese medicine composition is eye drop, and described preparation process is:
A, get described crude drug and add water extraction 2 times, first time adds 4-6 times amount soak by water 1-2 hour, and second time adds 3-5 times amount soak by water 1-2 hour, 2 extracting solution are merged, filter, when concentrating under reduced pressure obtains 80 DEG C, relative density is the extractum 1 of 1.04 ~ 1.10, and medicinal residues are for subsequent use;
B, medicinal residues are added 60-90% soak with ethanol 0.5-1.5 hour, extract twice, each 1-2 hour, merge extractive liquid, filters, concentrated, 80-160 order filters, and 6000-10000 rev/min centrifugal, gets supernatant, through the ultrafiltration post ultrafiltration that the molecular weight that dams is 5000-10000, when ultrafiltrate concentrating under reduced pressure relative density is 60 DEG C 1.25 extractum 2;
C, extractum 1 and extractum 2 to be mixed, add sodium chloride and the 60-80 distilled water doubly of 0.06% of mixing extractum gross mass, and to add concentration be that 4% sodium hydroxide solution regulates PH to be 6.0-7.0, add 0.2% active carbon again and boil 10 minutes, filter, subpackage, sterilizing, obtains eye drop.
For solving the problems of the technologies described above, the present invention reoffers a kind of dosage form for the treatment of the Chinese medicine composition of senile cataract, and pharmaceutical dosage form is: tablet, sugar coated tablet, film coated tablet, enteric coated tablet, capsule, hard capsule, soft capsule, oral liquid, suck agent, granule, electuary, honey pill agent, powder, sublimed preparation, solution, injection, suppository, plaster, syrup, powder or spray.
Described Chinese medicine composition, medicine is decocted decoction in use and is taken, and every day 1 dose, decocting takes at twice, and every 7 days is a course for the treatment of; When this Chinese medicine composition is the use of pill, capsule or tablet, three times on the one, every 7 days is a course for the treatment of.
Chinese medicine composition of the present invention has soothing liver and strengthening spleen, tonneau Xuan Fu, hard masses softening and resolving, or blood circulation promoting and blood stasis dispelling, changes tired sensible, improves microcirculation, is used for the treatment of various senile cataract symptom; And processing technology is easy, the little and convenient drug administration of toxic and side effects, medicament is easy to manufacture, new drug with low cost.The present invention is Chinese medicine composition, but the Chinese medicine that selected abnormal smells from the patient is gentle, makes the abnormal smells from the patient of Chinese medicine composition and light, adopts the therapies such as cold compress can greatly alleviate patient's discomfort.The present invention adopts the Chinese crude drug of different properties, has carried out scientific compatibility, can reach desirable therapeutic effect, and safety, toxic and side effects is little, and preparation is simple, and focus of going directly, healing time is short, not easily recurs after healing.
Detailed description of the invention
The traditional Chinese medical science thinks that primary disease is by worn with age, or natural endowment is not enough, or the reason such as wound, violence causes, and its pathogenesis mainly contains with below: the hepatic and renal YIN deficiency: liver opening at eye, and order obtains liver blood and can look, and pupil god belongs to kidney for water wheels, and kidney essense abundance is wonderful light then.If asthenia with age, vital essence is not filled, or because working with one's mind too much, cloudy blood specially dissipates, or natural endowment is not enough, then can cause deficiency of liver-blood, deficiency of the yin of the liver and deficiency of kidney-essence, and The liver and the kidney have a common source, essence and blood alternate, therefore the hepatic and renal YIN deficiency often exists simultaneously.Asthenia of essence and blood, Liver and kidney two is empty, then brilliant pearl is lost to support and forms cataract.Deficiency of spleen-QI and stomach-QI: old, deficiency of spleen-QI and stomach-QI, transporting mistake department, QI and blood is biochemical deficient, and eyes losing nutrition, then cause the generation of primary disease, and dysfunction of the spleen in transportation, ascending or descending movement of vital Qi is not normal, clear QI failing to ascend, turbid QI failing to descend, also can cause primary disease.The all few dynamic how quiet body of old people, blood fortune is therefore slowly sluggish, forms blood stasis for a long time.Again because of wound, violence, the frightened shake of brilliant pearl, qi depression to blood stasis, invade and harass refreshing water and gradually muddiness bleach.
External therapy of tcm is one of the most frequently used clinically external treatment of Chinese medicine, " Handbook of Prescriptions for Emergencies " of Jin Daige flood work, the Thousand Golden Prescriptions of the Tang Dynasty Sun Simiao, supplement to Thousand Golden Prescriptions, in " medical secrets of official " of Wang Taozhu and the Compendium of Material Medica of Ming Dynasty's Li Shizhen (1518-1593 A.D.), contained therapy has all related to external therapy of tcm.Because meridians have interior genus internal organs, outer network podomere, link up the exterior and the interior, run through upper and lower effect, so not only local patholoic change can be treated, but also reach the object for the treatment of systemic disease by external application.Medicine, by the stimulation at acupuncture point, local, penetrates through skin, excites through feeling pulse gas, promotes internal organs QI-blood circulation, plays therapeutical effect; Avoid oral simultaneously and inject the inconvenience that brings and misery, the head of a family and infant are easy to accept, and lasting medicine, avoid the first pass effect of liver and the interference of gastrointestinal factor and Degradation, reduce individual variation, rapid-action, strong drug action, hurtless measure, no pain, easy to use.
Semen Persicae in side, Flos Carthami, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae can blood circulation promoting and blood stasis dispelling, coordinate Sargassum can hard masses softening and resolving.Radix Rehmanniae Preparata, the Radix Paeoniae Alba can nourish blood.Fructus Mori, Fructus Ligustri Lucidi, Fructus Schisandrae Chinensis, Fructus Lycii, Rhizoma Dioscoreae can nourishing kidney-YINs, have can spleen invigorating, convergence.Four share can tonification healthy energy.Flos Eriocauli can nourishing kidney-yin, auxiliary upper four Chinese medicine thing.Flos Chrysanthemi, Pericarpium Citri Reticulatae can depressed liver-energy dispersing and QI regulating, regulate the operation of the gas of the whole body.Endothelium Corneum Gigeriae Galli can controlling nocturnal emission with astringent drugs.Coordinate the convergence of Magnetitum controlling nocturnal emission with astringent drugs, and can calm the nerves.Fructus Atriplicis Sibiricae, suppressing the hyperactive liver resolving depression, dispelling pathogenic wind for improving eyesight.Semen Cassiae, clearing away heat to improve acuity of vision, loosening bowel to relieve constipation.Massa Medicata Fermentata, invigorating the spleen and regulating the stomach; Promoting digestion and removing stagnation.Fructus Alpiniae Oxyphyllae, temperature compensation astringency inducing, warm spleen antidiarrheal, Semen Celosiae, liver heat removing, improving eyesight, nebula removing.Flos Eriocauli, wind and heat eliminating, improving acuity of vision and removing nebula.Rhizoma Seu Herba Bergeniae, the kidney invigorating; Improving eyesight; Shellfish tooth, clearing away heart-fire for tranquillization, suppressing the hyperactive liver improving eyesight; Faeces Vespertilionis, optic atrohic blindness; Nyctalopia; Conjunctival congestion and swelling pain; Subconjuctival hemorrhage.
Semen Persicae, bitter, sweet, flat.GUIXIN, liver, large intestine channel.Blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, relieving cough and asthma.For amenorrhea, dysmenorrhea , WEIJIA mass in the abdomen, injury from falling down, dryness of the intestine constipation.Semen Persicae bitter but sweet flavor and property are put down, and can enter the heart, liver, large intestine, and blood circulation promoting and blood stasis dispelling effect is very wide, availablely control the various worn-out disease of stagnation of blood stasis.In treatment, be good at treating abscess of internal organ, as lung abscess; Acute appendicitis is often held as wanting key medicine, is the peculiar performance Yu of its tool.The many matter profits of fat, the merit of tool loosening bowel to relieve constipation, only in recent years clinical specially with loosening bowel to relieve constipation then less use.Menorrhagia and contraindication in pregnancy.Semen Persicae and Flos Carthami are all the medicine of blood circulation promoting and blood stasis dispelling, and effect is all very extensive, often fit applications, and only Semen Persicae is kind controls lung abscess acute appendicitis, and has the effect of loosening bowel to relieve constipation; Flos Carthami is then good at promoting blood flow to regulate menstruation.Relieving constipation: cellulose can promote the wriggling of intestinal wall, helps digest, prevents from being hard and dry.Can intestinal be lubricated, stimulate defecation.Keep enteral feces moistening, in order to relieving constipation.Vitamin B group can be secreted by facilitating digestion liquid, maintains and promotes intestinal peristalsis promoting, being conducive to defecation.Regulating menstruation: relieving dysmenorrhea, or lumbago in menstrual period.Conditioning menstrual period long (short) or hypomenorrhea (many).Hemostasis: containing a large amount of colloid, generates platelet, has hemostasia effect.The patient of suitable hemorrhage.Suitable menorrhagia, the women of metrorrhagia.Makeup energy: carbohydrate containing, saccharide, can rapidly for health provides energy.
Flos Carthami, warm in nature, acrid in the mouth, promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, traumatic injury.When ancients often have what blood in vivo, often add Flos Carthami tate.Available one day twice foot bath boiled by bundle, and be suitable for various varicosis, peripheral neuritis, blood circulation is bad, lower limb numbness or the congestion such as livid purple.Irregular menstruation, puerperal abdonimal pain, lump in the abdomen, the diseases such as traumatic stasis swells and ache, ulcer sore pain.Come from " Bencao Tujing ": " red indigo plant flower, namely Flos Carthami also.The present has it everywhere.Other planted by ground threshing, and winter and cloth are in Radix Rehmanniae Preparata, and to spring raw Seedling, Xia Naiyou flower, the lower Qiu that does converges, thorniness, and pistil goes out on Qiu, and people from garden holds dew and adopt it, adopts to appear again, to stopping to the greatest extent.Solid in Qiu, white, as Semen Phaseoli is large.It spends suddenly and violently dry very red with dye, and makes swallow fat.After main product, disorders of blood is victory.In fact also same.Leaf quite like blue, therefore has blue name.”
Radix Angelicae Sinensis, these product are the dry root of umbelliferae angelica.Autumn end excavates, and removing fibrous root and silt, after moisture slightly evaporates, be bundled into wisp, upper canopy, with pyrotechnics slowly smoke-dried beancurd.Radix Angelicae Sinensis root is slightly cylindrical, and root upper end claims " returning head ", and main root claims " returning body " or " very little body ".Supporting root claims " Radix Angelicae Sinensis " or " returning lower limb ", all titles " Radix Angelicae Sinensis ".Radix Angelicae Sinensis can be enriched blood, and can invigorate blood circulation again, is referred to as and blood; Radix Angelicae Sinensis body is enriched blood, Radix Angelicae Sinensis removing blood stasis sweet in the mouth; Pungent; Bitter; Warm in nature.Return liver; The heart; Spleen channel.Hematonic; Emmenagogue; Analgesic.Enrich blood; Invigorate blood circulation; Menstruction regulating and pain relieving; Moisturize laxation.The all cards of blood deficiency; Menoxenia; Amenorrhea; Dysmenorrhea; Lump in the abdomen knot is poly-; Metrorrhagia; Asthenia cold abdominalgia; Flaccidity syndrome and arthralgia syndrome; Numbness of the skin; Dryness of the intestine dyschezia; Heavy after bloody dysentery; Ulcer sores; Injury from falling down.
Rhizoma Chuanxiong, blood circulation promoting and blood stasis dispelling; Activating QI to alleviate the depression; Wind-expelling pain-stopping.Textual criticism: come from Materia Medica of Decoction and cure mainly: medicine first choice for the treatment of headache.Menoxenia; Amenorrhea dysmenorrhea; The stagnant raw meat pain of the stasis of blood in puerperal; Lump in the abdomen lump; Pain in chest and hypochondrium; Have a headache dizzy; Anemofrigid-damp arthralgia; Traumatic injury; Ulcer sores." herbal classic ": main apoplexy enters brain headache, arthralgia due to cold, clonic spasm of the muscle emergency, gold wound, married woman's blood closes loss of fecundity." not Lu ": except cold dynamic in brain, on face, urticaria goes, order lacrimation, profuse nasal discharge and spittle, before we notice it as liquor-saturated, all cold gas, the hard pain of trusted subordinate, attacked by pestiferous factors, soldier is anxious to swell and ache, side of body wind pain, warming middle-JIAO endogenous cold.TAO Hong-Jing: tooth root bleeder, is recovered more than containing." property of medicine opinion ": control waist foot weak, hemiplegia, main afterbirth does not go out, and controls cold type of pain in abdomen." Japan hanako materia medica ": control a wind cutting, all gas, all strains, all blood, mend five kinds of over strain, strengthening bone and muscle, adjusts many arteries and veins, and broken crux stagnated blood, supports fresh blood, put on flesh, serious epistaxis, spits blood and hematuria, hemorrhoid complicated by anal fistula, brain carbuncle carbuncle on the back, and scrofula wart is gone to live in the household of one's in-laws on getting married, skin ulcer scabies, and evacuation of pus repercussive blood." medicine origin ": enrich blood, controls headache due to deficiency of blood.Wang Haogu: search irritability, tonifying liver blood, profit liver is dry, mends wind empty." detailed outline ": dampness, antidiarrheal dysentery, activating QI to alleviate the depression.Rhizome of chuanxiong Qiong, in blood, gas medicine also, liver bitter anxious with pungent benefit it, therefore blood deficiency person should it; Pungent to fall apart it, therefore stagnation of QI person should it." left biography " is sayed wheat Qu, is brought up imperial thoroughly wetting, and controls stomach ailment.Give and control dairrhea caused by pathogenic damp, often add two tastes, it should as sound.Dysentery is led to and the more than person of pain, is the cloudy thanks to stagnation of QI, and adding rhizome of chuanxiong in medicine is assistant, and gas promoting the circulation of blood is adjusted, and its disease stops immediately.Amplification on Canon of Materia Medica: rhizome of chuanxiong Qiong, moderns are at most used, women's head-ornaments wind can not fault also, so must help it with his medicine.
Radix Rehmanniae Preparata, yin nourishing of enriching blood, life essence-filling, marrow-benefitting.Apply all cards of 1. blood deficiency.The sweet Wen Zhirun of this product, nourishing YIN benefit essence, with hemopoietic, is the key medicine of the tonify deficiency that nourishes blood.Normal with Radix Angelicae Sinensis, the Radix Paeoniae Alba, the same use of Rhizoma Chuanxiong, treatment blood deficiency and yellow complexion, dizzy, cardiopalmus, has a sleepless night and menoxenia, metrorrhagia and metrostaxis etc., as SIWU TANG); If deficiency of heart-blood severe palpitation, can with the sedative such as Radix Polygalae, Semen Ziziphi Spinosae with using; If the empty cold in blood of metrostaxis and hyperamization, few abdomen cold type of pain person, can with the tonifying blood and arresting bleeding such as Colla Corii Asini, Folium Artemisiae Argyi, the same use of dispelling cold by warming the meridian medicine, as Ass-hide Glue and Argyi Leaf Decoction.2. all cards of the hepatic and renal YIN deficiency.This quality is moistened into kidney, and kind nourishing kidney yin, life essence-filling, marrow-benefitting is the key medicine of tonifying kidney-yin.Ancients call it " large tonifying five ZANG-organs is Kidney-Yin ", " the true water of large benefit ".Often be equal to use with Rhizoma Dioscoreae, Fructus Corni, the treatment hepatic and renal YIN deficiency, soreness of the waist and knees, seminal emission, night sweat, tinnitus, deafness and quench one's thirst, can invigorating the liver and kidney, beneficial marrow, as LIUWEI DIHUANG WAN; Also can be equal to the Rhizoma Anemarrhenae, Cortex Phellodendri, Carapax Et Plastrum Testudinis with treating deficiency of YIN osteopyrexia and fever, as dabuyin pill (" danxi's experiential therapy ").This product benefiting essence-blood, black beard and hair, the compatibilities such as normal and Radix Polygoni Multiflori, Radix Achyranthis Bidentatae, Semen Cuscutae, control blood and essence asthenia early whitening of beard and hair, as Qibao Meiran Dan (" collection of prescriptions with notes "); This product vital essence replenishing and marrow benifiting, bone and muscle strengthening, also can join Carapax Et Plastrum Testudinis, Herba Cynomorii, Rhizoma Cibotii etc., and treatment deficiency of the liver and kindey, five kinds of growth retardation five kinds of flaccidity in infant, as Huqian Wan (" collection of prescriptions with notes ").In addition, Radix Rehmanniae Preparata charcoal can stop blooding, and can be used for the blood deficiency such as metrorrhagia and goes out blood disorder.
The Radix Paeoniae Alba, cool in nature, bitter in the mouth acid, is slightly cold, has easing the affected liver of enriching blood, suppressing the hyperactive liver pain relieving.Yin fluid astringing receives the effects such as antiperspirant, is applicable to fever due to yin deficiency, menoxenia, the breast abdomen pain over the hypochondriac region, extremity contraction suddenly, dysentery stomachache, spontaneous sweating, metrorrhagia, the inferior disease of band.Paeoniflorin has antibacterial, antipyretic, antiinflammatory, increase coronary flow, improves the effect of myocardial nutritional flow, blood vessel dilating, antagonism acute myocardial ischemia, anticoagulant, calmness, analgesia, spasmolytic, antiulcer, adjustment blood glucose.Radix Paeoniae Alba decoct can suppress dysentery bacterium, streptococcus pneumoniae, escherichia coli, Bacillus typhi, Hemolytic streptococcus, bacillus pyocyaneus etc.
Fructus Atriplicis Sibiricae, suppressing the hyperactive liver resolving depression, dispelling pathogenic wind for improving eyesight.For dizziness due to hyperactivity of liver-YANG headache, hypochondriac pain due to stagnation of liverQI, headache due to pathogenic wind-heat, conjunctival congestion and swelling pain, the diseases such as skin pruritus.Tribulus terrestris, has nature to promote testosterone, increases strength, improve overall competitive state, have no side effect.
Fructus Schisandrae Chinensis as medical material, record the earliest be listed in Shennong's Herbal top grade.Ancients once evaluated like this Fructus Schisandrae Chinensis " the sweet acid of Fructus Schisandrae Chinensis skin and flesh, core first are worked hard, have saline taste this then the five tastes are all also." be perhaps the origin that it is named, Fructus Schisandrae Chinensis is warm in nature.Modern pharmacological research shows, Radix Schisandrae Bicoloris contains multiple nutritional components, as schizandrin, malic acid, citric acid, tartaric acid, succinic acid, fatty oil, volatile oil, saccharide, resin, vitamin C etc., also containing trace element such as tungsten, ferrum, manganese, zinc, phosphorus.Fructus Schisandrae Chinensis also has effect of the pathogenic microorganism breedings such as certain anti-bacteria, Fructus Schisandrae Chinensis water decoction to tubercule bacillus, bacillus subtilis, escherichia coli, Bacillus typhi, staphylococcus aureus, streptococcus, Diplococcus pneumoniae, have stronger inhibitory action.Utilize effect of its astringent therapy clinically, be used for astringing the lung, hidroschesis, arresting seminal emission antidiarrheal etc.
Rhizoma Dioscoreae sweet in the mouth, property are flat, enter lung, spleen, kidney channel; Not dry oiliness, have strengthening the spleen and tonifying the lung, stomach reinforcing the kidney invigorating, benefit of reinforcing the kidney essence, hearing-improing and eyesight improving, help the five internal organs, bone and muscle strengthening, long will are calmed the nerves, effect of life lengthening; Cure mainly that weakness of the spleen and stomach, lassitude, inappetence, chronic diarrhea and dysentery, insufficiency of lung-QI are dry, phlegm dyspnea cough, kidney qi loss, soreness of the waist and knees, lower limb flaccidity be weak, the red disease such as swollen, fat of frequent micturition of quenching one's thirst, seminal emission premature ejaculation, leukorrhagia nebulousurine, skin.Compendium of Material Medica summary five large functions " kidney tonifying gas, strengthening the spleen and stomach, stopping leak dysentery, reduce phlegm saliva, profit skin ".Rhizoma Dioscoreae cook congee or with crystal sugar simmer ripe after take, poor to health, colitis, deficiency of the kidney chronic diseases are all effective in cure.Strengthen the spleen and stomach: treat weakness of the spleen and stomach, have loose bowels, body is tired, lack of appetite, sweating due to debility.Lung benefiting nourishing kidney: this product is cold not dry, and sweet in the mouth matter is moistened, that can treat that lung suffers from a deficiency of the kidney and damage quenches one's thirst, passes out semen, is with inferior disease, is described as angle's medicine.
Pericarpium Citri Reticulatae temperature; Pungent, bitter; Return the bitter substance of spleen, lung meridian Pericarpium Citri Reticulatae with limonin and bitter principle for representative " limonoid ", this limonoid taste is gentle, soluble in water, contributes to the digestion of food.When Pericarpium Citri Reticulatae is used for cooking dishes.Its bitterness and other tastes are in harmonious proportion mutually, can form original in style local flavor.Pericarpium Citri Reticulatae contains the compositions such as volatile oil, hesperidin, vitamin B, C, and the volatile oil contained by it has gentle stimulation to gastrointestinal tract, can the secretion of facilitating digestion liquid, gets rid of pneumatosis in intestinal tube, increases appetite.Pericarpium Citri Reticulatae is also conventional Chinese medicine simply, has effect of the spleen invigorating of ventilation, drying dampness to eliminate phlegm, the greasy lasting of solution, stopping nausea and vomiting by lowering the adverse flow of QI.
Semen Cassiae, clearing away heat to improve acuity of vision, loosening bowel to relieve constipation.For the puckery pain of conjunctival congestion, the many tear of photophobia, has a headache dizzy, poor vision, constipation.Return liver, kidney, large intestine channel.There is effect of fat-reducing.Control wind heat acute conjunctivitis, optic atrohic blindness, nyctalopia, hypertension, hepatitis, cirrhotic ascites, habitual constipation.1. TAO Hong-Jing: Semen Cassiae, leaf is as Semen Cassiae Sopherae, and son likeness in form Horse hoof, exhales as Horse hoof Semen Cassiae.With when smashing to pieces.Do not have Semen Cassiae again, be luxuriant Herba Artemisiae, in low-grades also.2. " detailed outline ": also, the name with the merit of improving eyesight, has again Semen Cassiae, Concha Haliotidis, all with merit person to this Horse hoof Semen Cassiae.Semen Cassiae and Semen Celosiae, the so-called luxuriant Artemisia of Tao Shi is also.Semen Cassiae has two kinds, a kind of Horse hoof Semen Cassiae, and stem is high by three, four chis, and leaf is greater than Herba Medicaginis and this little last Ji, opens silk tree daytime, two biphase notes.Autumn opens sulphureum Baker, and five go out.Knot angle is as nascent thin Semen vignae sinensis, and long five, six cun, the tens of grain of angle neutron, irregular connected, shape is as Horse hoof, and dark green, enters eyes medicine the best.A kind of Cassia sophera.All can make distillers yeast for two kinds, custom is exhaled as exclusive cylinder.But the tender Seedling of Semen Cassiae Sopherae and flower and silver coin all can be boiled and eat and order cakes and sweetmeats, and all tough hardship in Horse hoof Semen Cassiae Seedling angle, not edible yet.
Fructus Lycii, nourishing the liver and kidney, replenishing vital essence to improve eyesight; For chronic consumptive disease damage of essence, soreness of waist and knee joint; Vertigo and tinnitus, interior-heat Xiao are thirsty, blood deficiency and yellow complexion, and blurred vision is failed to understand.Cure mainly caused by liver and kidney deficiency; Have a dizzy spell; Visual deterioration; Soreness of the waist and knees; Seminal emission is quenched one's thirst; Cough due to consumptive disease.The hepatic and renal YIN deficiency, blood deficiency, soreness of the waist and knees, chronic ocular disease, have a dizzy spell, the condition subject such as asthenia is thin and weak, diabetes, hypertension, hyperlipemia, arteriosclerosis, chronic hepatitis, fatty liver and cancer patient's radiotherapy, suitable edible after chemotherapy.The heat syndrome that all void are hyperfunction, after such as pulmonary tuberculosis later stage, diabetes yin asthenia generating intrinsic heat, infantile measles, the condition subject such as not move back suitable edible for deficiency-heat.
Massa Medicata Fermentata, invigorating the spleen and regulating the stomach; Promoting digestion and removing stagnation.Main retention of food and drink; Dyspepsia; Distension and fullness in the abdomen; Inappetence; Vomiting dysentery.Control retention of food and drink, feeling of stuffiness in chest abdominal distention, vomiting dysentery, postnatal blood stasis is suffered from abdominal pain, and children's's enlarged abdomen heavily fortified point is long-pending.Zhang Yuansu: nourishing the stomach gas.Control also white chaste tree.Materia Medica of Decoction: treat pathogenic wind in internal organs, the therapeutic method to keep the adverse QI flowing downwards in tune, whet the appetite the dyspepsia that disappears.Main cholera heart diaphragm gas, expectorant is inverse, and relieving restlessness , Po Disorder ties and tonify deficiency, removes cold air, fills in except in the intestines and stomach, not lower food.Can control children's's abdomen hard large as dish, fullness in the chest, frequent fetal movement, or lumbago robs the heart, hematochezia is more than." detailed outline ": removing stagnancy of indigested food and making QI downward, expectorant lets out dysentery distension against cholera.Sprain lumbago person, forged wine decoction being taken warmly of quenching effective, and married woman's wish in puerperal galactopoiesis person, stir-fry is ground wine and taken two money, day two." book on Chinese herbal medicine is stated ": cure the wound summer-heat, being affected by fluid-retention is eaten, and hinders overstrain, and malaria flatulence due to stagnation of QI is demonstrate,proved, and edema distension gathers, cough due to fluid-retention, and vomiting regurgitation, cholera, blood-retention, pained, gastric abscess, hypochondriac pain, numbness flaccidity is dizzy, heavy sensation of the body, can not eat, jaundice." book on Chinese herbal medicine is new again ": the scrofula that disappears cellulitis tumor.
Radix Salviae Miltiorrhizae, there is promoting blood circulation to remove blood stasis, detumescence hemostasis, anti-inflammatory analgetic, menstruction regulating and pain relieving, coronary artery dilator, improve myocardial ischemia situation, reduce blood pressure, calm the nerves with all worries set aside, blood sugar lowering and the effect such as antibacterial, to menoxenia, amenorrhea dysmenorrhea, lump in the abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, the diseases such as angina pectoris have certain curative effect.In addition, modern medicine experiment proves, Radix Salviae Miltiorrhizae also has anti-platelet aggregation, reduces the function of blood viscosity and the inside and outside blood coagulation system of adjustment, is the natural Chinese medicine that a kind of safety treats again cardiovascular disease reliably.For costa sternales hypochondriac pain, rheumatic arthralgia, lump in the abdomen lumps, and skin infection swells and ache, and tumbling down is grieved, menoxenia, amenorrhea dysmenorrhea, puerperal stasis of blood pain etc.Treatment costa sternales pain, lump in the abdomen caking, and menoxenia, amenorrhea dysmenorrhoea have good effect, normal and Rhizoma Chuanxiong compatibility is applied.Belonging in qi depression to blood stasis in treatment breast abdomen pain, often coordinating the medicine such as Fructus Amomi, Lignum Santali Albi with using.Enter nutrient blood for epidemic febrile disease heat, body sends out macule, coma is irritated.Normal with Radix Rehmanniae, Cornu Bubali, Radix Scrophulariae etc. medicine use together.For severe palpitation, insomnia.Often coordinate with the medicine such as Semen Ziziphi Spinosae, Semen Platycladi with using.
Fructus Alpiniae Oxyphyllae, temperature compensation astringency inducing, warm spleen antidiarrheal , Gu Dan takes the photograph saliva, and the kidney warming controlling nocturnal emission with astringent drugs reducing urination, cures mainly spleen-kidney vacuity cold, abdominal pain diarrhea; Or kidney qi deficiency and coldness frequent micturition, the enuresis, seminal emission, nebulousurine; Or saliva outflow and can not effector in chronic diarrhea caused by Deficiency and coldness of spleen and stomach and mouth.1. Materia Medica of Decoction: " hands, meridian of Foot-TAI YIN, meridian of Foot-SHAO YIN." 2. " Thunder God concocts property of medicine solution ": " enters spleen, stomach, kidney three warp." 3. " book on Chinese herbal medicine is through separating ": " enters liver channel of foot-Jueyin, lung meridian.
Fructus Mori, nourishing YIN and benefiting blood; Promote the production of body fluid; Intestine moistening.Having a dizzy spell of main deficiency of the liver and kindey and blood deficiency damage of essence; Soreness of waist tinnitus; Early whitening of beard and hair; Insomnia and dreamful sleep; Tianjin wound is thirsty; Quench one's thirst; Dryness of the intestine constipation.Fructus Mori both can food, can be used as medicine again, and the traditional Chinese medical science thinks the acid of Fructus Mori sweet in the mouth, cold nature, enters the heart, liver, kidney channel, is strengthening by means of tonics, the good fruit of the heart nourishing and intellengence improving, the effects such as Fructus Mori has YIN nourishing of enriching blood, promoting the production of body fluid to quench thirst, and intestine moistening is dry, Fructus Mori cures mainly deficiency of YIN-blood and having a dizzy spell of causing, tinnitus cardiopalmus, irritated insomnia, soreness of the waist and knees, early whitening of beard and hair, the diseases such as xerostomia, constipation with dry stool of quenching one's thirst.
Fructus Ligustri Lucidi, tonifying liver kidney yin, crow must improving eyesight, and modern medicine study thinks that Fructus Ligustri Lucidi can suppress the effect of helicobacter pylori to treat gastropathy, also has the treatment suppressing purine abnormal metabolism for gout and hyperuricemia.For the hepatic and renal YIN deficiency, soreness of waist tinnitus, early whitening of beard and hair; Unseeing, poor vision; Fever due to yin deficiency, gastropathy and gout and and hyperuricemia.1, Deficiency and coldness of spleen and stomach and insufficiency of kidney-YANG person prohibit clothes.2, Deficiency and coldness of spleen and stomach is had loose bowels and yang deficiency person avoids clothes.3, " Bencao Jingshu ": when assorted guarantor's taste medicine and red warm roughly the same the executing of green pepper, does not then probably have the trouble that stomachache work is let out.
Flos Chrysanthemi, Flos Chrysanthemi is Compositae herbaceos perennial, is one of parts of generic medicinal plants of Chinese tradition, mainly with head inflorescence hyoscine.Record according to ancient books, Flos Chrysanthemi sweet-bitter flavor, cold nature; There are the effects such as loose wind heat clearing away, liver heat removing and eyesight improving and detoxicating, relieving inflammation. puckery to xerostomia, hyperactivity of fire, order, or the limbs pain caused by wind, cold, wet, numb disease all have certain curative effect.Cure mainly cold anemopyretic, headache etc.Preventive and therapeutic effect is had to dizzy, headache, tinnitus.Flos Chrysanthemi have Herba Dendranthematis indici and family chrysanthemum point, wherein family chrysanthemum liver heat removing and eyesight improving, the loose fire of Herba Dendranthematis indici toxic removing, sweetness and bitterness is slightly cold, heat-clearing and toxic substances removing, all has certain effectiveness to eye strain, headache, hypertension etc.In Compendium of Material Medica, the drug effect of chrysanthemum scented tea is also documented in detail: property is sweet, be slightly cold, there is effect of loose wind heat, suppressing the hyperactive liver improving eyesight.Shennong's Herbal is thought, Flos Chrysanthemi scented tea can " lead all dizziness due to wind, swell and ache, order wish is de-, the dead flesh of skin, aversion to wind arthralgia chiefly caused by damp pathogen, take promoting the circulation of QI for a long time, making light of one's life by commiting suicide endures hardships prolongs life.”
Sargassum, softening the hard mass; Expectorant; Diuretic; Detumescent.Thyromegaly, item submental lymph nodes tuberculosis.Eliminating stagnation gas carbuncle, abdomen inner product block, distending pain, abdomen hollow are rung.Also can descend 12 kinds of edema, treat between skin and gather sudden and violent bursting, stay depressed heat, diuresis.Cure mainly: scrofula; Goiter; Gather; Edema; Foot gas; Painful and swollen testis; (Epileptic is ruined) hernia.1. " herbal classic ": main goiter gas, core under neck, broken eliminating stagnation gas, the hard gas of carbuncle lump in the abdomen, rings in abdomen up and down, lower 12 edema.2. " not Lu ": treat between skin and gather, sudden and violent Huang, stays gas, accumulation of heat, diuresis.3. " property of medicine opinion ": control dry phlegm-syndrome knot full, treat hernia tenesmus, pain core swells, and removes active borhorygmus, faintly utters a word.4. the Meng numerous: led the cloudy gas of man, often eat it, disappear man Huang disease.5. " Haiyao Bencao, Oversea Materia Medica ": main dyspepsia does not disappear, five separate expectorant stop up, aqueous vapor edema, beriberi, sensation of gas rushing.6. " book on Chinese herbal medicine covers bamboo fish trap ": control scrofula between item, wart capsule under the neck that disappears, dredging water passages, the logical difficulty in urination becomes to drench, and removing water retention by purgation gas, except distension swells.7. " modern Practical Chinese medicinal ": control the diseases such as chronic tracheitis.
Endothelium Corneum Gigeriae Galli, promoting digestion and invigorating the stomach is aid digestion, arresting seminal emission.Can gastric secretion be promoted, improve gastric acidity and eupepsy, stomach motor function is obviously strengthened, rapid gastric emptying.Removing food stagnancy is stagnant, strengthening the spleen and stomach.Control food stagnation distension, vomiting regurgitation, dysentery, infantile malnutrition, quenches one's thirst, incontinence of urine, sore throat tonsillitis, ulcerative gingivitis aphtha.1. " herbal classic ": master lets out profit.2. " not Lu ": main normal urination, incontinence of urine, heat extraction be only tired.3. " Japan hanako materia medica ": stopping leak essence, and hematuria, metrorrhagia, leukorrhagia, hemorrhoidal hamorrhage, dysentery.4. " the southern regions of the Yunnan Province book on Chinese herbal medicine ": alleviating distention in middle-JIAO spleen invigorating, help digestion mill stomach.Control children's's breast food knot stagnant, the large muscle of tripe is blue or green, mass in the abdomen infantile malnutrition.5. " detailed outline ": control children's's intermittent fever due to retention of food, treatment adult is dripping, regurgitation, and the wine that disappears amasss, main inflammation of the throat, tonsillitis, all aphthas, all skin ulcers of ulcerative gingivitis.6. " book on Chinese herbal medicine is stated ": control diseases due to endogenous heat of ZANG FU organs.7. " herbal classic is met former ": control eyes and hide from view.8. " book on Chinese herbal medicine is new again ": reduce phlegm, regulate the flow of vital energy, dampness removing.9. " Records of Tradition Chinese and Western Medicine in Combination ": control Xuan ringworm abdominal mass, stimulate the menstrual flow and close.
Magnetitum, suppressing the hyperactive liver and subsiding YANG; Calm the nerves relieving convulsion; Hearing-improing and eyesight improving; Helping inspiration to relieve asthma.Cure mainly: main dizzy; Order flower; Deaf; Tinnitus; Palpitation with fear; Insomnia, dyspnea of suffering from a deficiency of the kidney.1. Collective Notes to the Canon of Materia medica: Radix Bupleuri makes for it.Dislike Paeonia suffruticosa, Folium illicii Lanceolati.Fear Huangshi fat.Kill ferrum poison.2. " Bencao Congxin ": feel frustrated in important city, can temporary and can not be of a specified duration.More taste void person, should not take, take for a long time.
Semen Celosiae, liver heat removing, improving eyesight, nebula removing.For liver-heat conjunctival congestion, nebula of looking unfamiliar film, blurring of vision, dizziness due to liver-fire.1, liver heat removing and eyesight improving: be mainly used in flaming up of liver-fire, conjunctival congestion and swelling pain, the raw nebula film of order, poor vision.2, these product also can be used for liver-fire hypertension.
Rhizoma Seu Herba Bergeniae, another name stone Chinese cabbage.Medical material Ji Yuan: be the herb of goatweed triaenophora rupestris.Latin plant animal mineral name: Triaenophora rupestris(Hemsl.) solereder [Rehmannia rupestris Hemsl.].Gather and store: summer, autumn gather, and dry.Ecological environment: be born on the cliff of height above sea level 290-1200m.Be distributed in Hubei, Sichuan.Sweet in the mouth; Cool in nature.Cure mainly the kidney invigorating; Improving eyesight; Regulating menstruation.The confused many tear of argument; Lumbago due to renal deficiency; Menoxenia.
Shellfish tooth, cures mainly clearing away heart-fire for tranquillization, suppressing the hyperactive liver improving eyesight.For dysphoria and insomnia of palpitating with fear, children's's macule, conjunctival congestion nebula.Medical material practises point Concha Erosariae seu Cypraeae and cowry shell two class, is used as medicine with Concha Erosariae seu Cypraeae for many.Concha Erosariae seu Cypraeae is Cypraeidae animal erosaria caputserpentis Erosaria (Ravitrona) caputserpentis (L.), Cypraealynx Cypraca (Lyncina) lynx (L.), silk ribbon attached to an official seal or a medal shellfish Mauritia arabica (L.) or eyeball shellfish (plan name) Erosaria (Ravitrona) helvola (L.).Cowry shell is Cypraeidae animal ring grain Cypraeamoneta Monetaria (Ornametaria) annulus (L.), intends Fructus Jujubae shellfish Erronea errones (L.) or Cypraeamoneta Monetaria moneta (L.).Be used as medicine with shell.Between 5 ~ July, fish for from marine, except fleshing, clean and dry.Nature and flavor are salty, flat.
Flos Eriocauli, wind and heat eliminating, improving acuity of vision and removing nebula.Cure mainly and control corneal nebula, night blindness, headache, toothache, sore throat, epistaxis.1, wind heat conjunctival congestion and swelling pain, photophobia, nebula of looking unfamiliar film.The frivolous liter of this product falls apart, and kind evacuates women's head-ornaments wind heat, improving acuity of vision and removing nebula, attacks caused conjunctival congestion and swelling pain, the many tear of photophobia, nebula of looking unfamiliar film person with controlling in wind heat, can with the compatibility such as Herba Schizonepetae, Semen Cassiae, Radix Gentianae, as Flos Eriocauli soup (" Precious Book of Ophthalmology ").2, headache due to pathogenic wind-heat: get its dispelling wind and heat pathogens and control headache due to pathogenic wind-heat, it is medicinal often to join Herba Menthae, Flos Chrysanthemi, Fructus Arctii etc.Flos Eriocauli is used for cataract, the many tear of photophobia, nyctalopia.Flos Eriocauli light weight is pungent loose, and being longer than and evacuating wind-heat of liver channel and improving acuity of vision and removing nebula, is the product that ophthalmology is conventional.Cataract caused by all wind heat, photophobia is shed tears, and often joins Herba Equiseti Hiemalis, Flos Buddlejae, Fructus Atriplicis Sibiricae with dispelling wind and heat pathogens; If wind heat more very, liver-fire is partially prosperous, and conjunctival congestion and swelling pain is more acute, and join Radix Gentianae, Flos Chrysanthemi, Semen Cassiae etc., with dispelling wind and removing heat, liver heat removing and eyesight improving, as " Precious Book of Ophthalmology " Flos Eriocauli soup; If corneal nebula after pox, then join Periostracum Cicadae, testa mungo with dispelling pathogenic wind for improving eyesight, heat-clearing and toxic substances removing, as " Standards of Diagnosis and Treatment " Flos Eriocauli falls apart.As for treatment nyctalopia, Gu Qingcao can with Hepar Sus domestica, or join Rhizoma Atractylodis, the same use of Faeces Vespertilionis again, with liver-benefiting eye-brightening." proper book on Chinese herbal medicine ": " obtain wether liver, control night blindness in children." " must book on Chinese herbal medicine be joined ": " join Pheretima, Olibanum smokes nose, control headache; Join corneal nebula after Pulvis concha Mactrae, Hepar Sus domestica treatment of smallpox.
Faeces Vespertilionis, optic atrohic blindness; Nyctalopia; Conjunctival congestion and swelling pain; Subconjuctival hemorrhage; Inside and outside cataracta; Infantile malnutrition; Scrofula; Malaria.1. " detailed outline ": Faeces Vespertilionis and Vespertilio all faint cloudy Liver Channel blood system medicine also, energy promoting blood circulation to remove stagnancy, therefore corneal nebula blindage of controlling, malaria infantile malnutrition is shied, and drench band, scrofula, carbuncle, the disease of the moon of all fainting also.2. " Bencao Jingshu ": Faeces Vespertilionis, the main improving eyesight of moderns, controls blindness and hides from view.Its acrid in the mouth is trembled with fear, and is into meridian of Foot-JUE YIN medicine, and " herbal classic " institute lead all cards, total belong to be through send out, get the loose inside and outside knot of its pungent energy stagnant, the energy dehematize steam heap soil or fertilizer over and around the roots therefore also of trembling with fear.Though right main treatment is many, property has exclusive, and outside improving eyesight, Yu Jieke slightly.3. " herbal classic ": interarea carbuncle, pain when skin is washed, QI and blood in abdomen, broken cold and heat gather, except palpitation with fear.4. " not Lu ": remove dark complexion.5. Tang Materia Medica: wine takes tool for weighing medicine in ancient China, main dead fetus in the uterus.6. " Japan hanako materia medica ": scrofula is controlled in speculation in stocks.7. amplification on Canon of Materia Medica: close infantile malnutrition medicine.8. " detailed outline ": control blindness, hide from view, improving eyesight, except malaria.
The agent of embodiment 1 cold compress
The preparation process of cold compress agent of the present invention is: first by Semen Persicae 1500g, Flos Carthami 1200g, Radix Angelicae Sinensis 1000g, Rhizoma Chuanxiong 1800g, Radix Rehmanniae Preparata 1200g, Radix Paeoniae Alba 1500g, Fructus Atriplicis Sibiricae 1200g, Semen Cassiae 1400g, Fructus Lycii 1800g, Massa Medicata Fermentata 1200g, Radix Salviae Miltiorrhizae 1000g, Fructus Alpiniae Oxyphyllae 1200g, Fructus Mori 1400g, Fructus Ligustri Lucidi 1200g, Flos Chrysanthemi 1500g, Rhizoma Dioscoreae 1000g, Sargassum 1200g, Fructus Schisandrae Chinensis 1500g, Endothelium Corneum Gigeriae Galli 1200g, Pericarpium Citri Reticulatae 1500g, Magnetitum 1000g, Semen Celosiae 1200g, Rhizoma Seu Herba Bergeniae 1500g, shellfish tooth 2000g, Flos Eriocauli 1600g and Faeces Vespertilionis 1200g, be ground into coarse powder, pulverize further again, cross 120 mesh sieves, collect and obtain fine powder a by the fine powder of 120 mesh sieves, again the coarse powder not by 120 mesh sieves is dropped into multi-function extractor and extract twice, first time adds 8 times amount soak by water 2 hours, and second time adds 6 times amount soak by water 2 hours, merges twice decocting liquid, filters to get filtrate, filtrate heating is concentrated into pasty state, puts into after 80 DEG C, baking oven is dried and cool, grind to form fine powder b, for subsequent use after fine powder a is mixed with fine powder b, then by Borneolum Syntheticum 1500g extraction by steam distillation, crystal c is obtained, added by crystal c in the mixture of fine powder a and fine powder b, mixing adds qs glycerin, and glycerol addition accounts for 6 times of fine powder mixture quality, furnishing paste, loads in colored bottle after sterilization, and it is for subsequent use to put into refrigerator-freezer 0 DEG C-4 DEG C storage.
Embodiment 2 eye drop
The preparation process of eye drop of the present invention is:
A, get Semen Persicae 1500g, Flos Carthami 1200g, Radix Angelicae Sinensis 1700g, Rhizoma Chuanxiong 1000g, Radix Rehmanniae Preparata 1300g, Radix Paeoniae Alba 1000g, Fructus Atriplicis Sibiricae 1200g, Semen Cassiae 1500g, Fructus Lycii 1000g, Massa Medicata Fermentata 1200g, Radix Salviae Miltiorrhizae 1800g, Fructus Alpiniae Oxyphyllae 1400g, Fructus Mori 1200g, Fructus Ligustri Lucidi 1000g, Flos Chrysanthemi 1300g, Rhizoma Dioscoreae 1400g, Sargassum 1800g, Fructus Schisandrae Chinensis 1200g, Endothelium Corneum Gigeriae Galli 1000g, Pericarpium Citri Reticulatae 1200g, Magnetitum 1500g, Semen Celosiae 1200g, Rhizoma Seu Herba Bergeniae 1600g, shellfish tooth 1200g, Flos Eriocauli 1000g and Faeces Vespertilionis 1500g, add water extraction 2 times, first time adds 6 times amount soak by water 2 hours, second time adds 5 times amount soak by water 1 hour, 2 extracting solution are merged, filter, when concentrating under reduced pressure obtains 80 DEG C, relative density is the extractum 1 of 1.04 ~ 1.10, medicinal residues are for subsequent use,
B, medicinal residues are added 80% soak with ethanol 1.5 hours, extract twice, each 2 hours, merge extractive liquid, filters, concentrated, 80-160 order filters, 6000-10000 rev/min centrifugal after supernatant, be the ultrafiltration post ultrafiltration of 5000-10000 through the molecular weight that dams, when ultrafiltrate concentrating under reduced pressure relative density is 60 DEG C 1.25 extractum 2;
C, extractum 1 and extractum 2 to be mixed, add sodium chloride and the 60-80 distilled water doubly of 0.06% of mixing extractum gross mass, and to add concentration be that 4% sodium hydroxide solution regulates PH to be 6.0-7.0, add 0.2% active carbon again and boil 10 minutes, filter, subpackage, sterilizing, obtains eye drop.
Embodiment 3 tablet
The preparation process of Tablets is: get Semen Persicae 1200g, Flos Carthami 1800g, Radix Angelicae Sinensis 2000g, Rhizoma Chuanxiong 1500g, Radix Rehmanniae Preparata 1200g, Radix Paeoniae Alba 1800g, Fructus Atriplicis Sibiricae 1000g, Semen Cassiae 1300g, Fructus Lycii 1200g, Massa Medicata Fermentata 1600g, Radix Salviae Miltiorrhizae 1400g, Fructus Alpiniae Oxyphyllae 1000g, Fructus Mori 1500g, Fructus Ligustri Lucidi 1800g, Flos Chrysanthemi 1800g, Rhizoma Dioscoreae 1000g, Sargassum 1500g, Fructus Schisandrae Chinensis 1800g, Endothelium Corneum Gigeriae Galli 1000g, Pericarpium Citri Reticulatae 2100g, Magnetitum 2800g, Semen Celosiae 1000g, Rhizoma Seu Herba Bergeniae 1800g, shellfish tooth 1400g, Flos Eriocauli 1500g and Faeces Vespertilionis 1700g, put into 10 times amount ethanol, heating and refluxing extraction 2 times, each 45 minutes, extract active ingredient, 2 extracting solution are merged and leaves standstill, obtain extracting solution a, medicinal residues are for subsequent use, medicinal residues are added 10 times of water gagings, heating and refluxing extraction 3 times, each 1 hour, 3 extracting solution are merged to obtain extracting solution b, merge extractive liquid, a and extracting solution b, decompression recycling ethanol to be concentrated into liquor strength be 0.5g crude drug/mL, after sucking filtration, when obtaining 20 DEG C, relative density is the filtrate of 1.06, above-mentioned filtrate is the macroporous adsorptive resins eluting twice of 10L through volume, first uses deionized water or the distilled water eluting of 10 times of resin column volumes, then uses 95% ethanol elution of 5 times of resin column volumes, collects ethanol elution, removes solvent, obtains raw material medicinal liquid, add starch and be pressed into tablet.
Embodiment 4 pill
The preparation process of the present invention's honey refining pill is: get Semen Persicae 1600g, Flos Carthami 2000g, Radix Angelicae Sinensis 1800g, Rhizoma Chuanxiong 1300g, Radix Rehmanniae Preparata 1000g, Borneolum Syntheticum 1500g, Radix Paeoniae Alba 1200g, Fructus Atriplicis Sibiricae 1500g, Semen Cassiae 1100g, Fructus Lycii 2000g, Massa Medicata Fermentata 1500g, Radix Salviae Miltiorrhizae 1200g, Fructus Alpiniae Oxyphyllae 1100g, Fructus Mori 1600g, Fructus Ligustri Lucidi 1000g, Flos Chrysanthemi 1400g, Rhizoma Dioscoreae 1300g, Sargassum 1000g, Fructus Schisandrae Chinensis 2100g, Endothelium Corneum Gigeriae Galli 1600g, Pericarpium Citri Reticulatae 1500g, Magnetitum 1800g, Semen Celosiae 1300g, Rhizoma Seu Herba Bergeniae 1800g, shellfish tooth 1500g, Flos Eriocauli 1200g and Faeces Vespertilionis 1000g, soak 1 hour, heated and boiled 30 minutes, filter, filtrate is for subsequent use, filtering residue adds water, second time heating, and boil 30 minutes, refilter, filtrate is for subsequent use, filtering residue adds water again, for the third time heated and boiled 30 minutes, filters, three filtrates are combined, heating be concentrated into pasty state, put into baking oven, control at 75 DEG C, be cooled to after oven dry Powdered be mixed in right amount with Mel together be twisted into ball, with every 5g be one ball wax seal packaging.
Pharmacology pharmacodynamic is reported
1, acute toxicity test report
Test method: with the eye drop of the embodiment of the present invention 2 for object, selects 20 white mice to test, is divided into matched group and test group, each 10, to 10 white mice intravenous injections of test group, observes 7 for 3 times that get clinical consumption per day.20 white mouse are all strong as a result deposits, and its activity, diet, hair, Excreta are no abnormal, have no toxic reaction.Toxicity test proves, the not toxic effect of this medicine and untoward reaction, clinical practice is safe and reliable.
2, long term toxicity test report
Test method one: with the tablet of the embodiment of the present invention 3 for object, the Canis familiaris L. selecting 20 ripe vital signs identical is tested, be divided into matched group one group and test group three groups, carry out same food nursing to 20 Canis familiaris L.s, 15 1 times, 3 times and 5 times of mixing clinical medicine consumption respectively in food of test group group are fed.Nursing is carried out two months, and observe 20 Canis familiaris L.s, animal all survives, and has no toxic reaction.Blood and bone marrow smear, internal organs pathological section is there are no the pathological change of toxicity meaning.
Test method two: using the pill of the embodiment of the present invention 4 as object, selects 20 rats to test.Be divided into two groups at random, respectively food 5 times and 10 times of pharmaceutical quantities filled with to it.Carry out 1 month continuously, observe, 20 rats, before vital sign and dispensing, there is not any untoward reaction in indifference, behavior is normal, has no toxic reaction.
3, hypersensitive test report
Test method: using the cold compress agent of the embodiment of the present invention 1 as object, the Cavia porcellus selecting 30 vital signs identical is tested.Be divided into 5 groups at random, one group of matched group and four groups of test group, carry out subcutaneous administration respectively to 24 Cavia porcelluss of test group, dosage is 2LD50 respectively, 4 LD50,6 LD50,8 LD5(LD50 are about 1.5g/kg), medication carries out 4 weeks.Observing the Cavia porcellus of four groups of test group and one group of matched group, all there is not any discomfort in skin, and behavior is normal, and blood internal organs have no pathological changes.
Tested by pharmacology pharmacodynamic, can learn, Chinese medicine composition of the present invention, not there is system custom, store toxicity and sensitization.
Clinical data
1. data and method
During selecting in July ,-2012 in July, 2010, the Aged-related Cataract Patients that my institute receives amounts to 300 examples.Wherein, in 300 routine patients, the case patient of age the right side of fifty has 50 examples, age 50-60 year case patient 100 example, the case patient of age above 60 years has 150 examples.In patient, in various degree suffer from senile cataract, symptom for oculogyral shade at the moment, gradual Silent Neuritis visual deterioration, monocular diplopia or look more, iridization, photophobia and dazzle.Eyes are ill, and have successively, the order of severity differs.This 300 routine patient is divided at random matched group 120 example and treatment group 180 example, carries out treatment contrast.
2. criterion of therapeutical effect
Recovery from illness: senile cataract symptom is fully recovered; Effective: symptom is obviously alleviated; Invalid: symptom is invalid.
3. Therapeutic Method
180 for the treatment of group routine patients are divided into four groups by 3.1 at random, treat according to embodiment of the present invention 1-4.
Treat one group: the 45 routine patients of this treatment group use the cold compress agent of embodiment 1 to treat.Treat every bu morning, noon and afternoon three times, after being cleaned by eye, the cold compress agent of 5g being spread on eye at every turn and carry out washing away for 20 minutes, 7 days is a course for the treatment of, and 1-3 the course for the treatment of is carried out in treatment.After medication, have 42 routine patients symptomatic's recoveries from illness, 1 routine patients symptomatic is effectively alleviated, and 2 routine patients are invalid.In medication process, patient has no side effect.With nearly half a year, not recurrence.
Treat two groups: the 45 routine patients of this treatment group use the eye drop of embodiment 2 to treat.Treat every bu morning, noon and afternoon three times, be that the eye drop of 2% is aimed at canthus and carried out dripping a medicine by concentration, each medicine 2-3 that drips drips, and within 7 days, be a course for the treatment of, 1-3 the course for the treatment of is carried out in treatment.After medication, have 43 routine patients symptomatic's recoveries from illness, 1 routine patients symptomatic is effectively alleviated, and 1 routine patient is invalid.In medication process, patient has no side effect.With nearly half a year, not recurrence.
Treat three groups: the 45 routine patients of this treatment group use the tablet of embodiment 3 to treat.Treat every bu morning, noon and afternoon three times, each two panels, the dosage of every sheet 0.4g 7 days is a course for the treatment of, and 1-3 the course for the treatment of is carried out in treatment.After medication, have 41 routine patients symptomatic's recoveries from illness, 3 routine patients symptomatic are effectively alleviated, and 1 routine patient is invalid.In medication process, patient has no side effect.With nearly half a year, not recurrence.
Treat four groups: the 45 routine patients of this treatment group use the pill of embodiment 4 to treat.Treat every bu morning, noon and afternoon three times, each ball, every ball is 5g, within 7 days, is a course for the treatment of, and 1-3 the course for the treatment of is carried out in treatment.After medication, have 44 routine patients symptomatic's recoveries from illness, 1 routine patients symptomatic is effectively alleviated, and 0 routine patient is invalid.In medication process, patient has no side effect.With nearly half a year, not recurrence.
3.2, by 120 of matched group routine patient's random packet, are divided into three groups, use different medicines to treat.
Contrast one group: 40 people of this matched group use Benzydalysine eye drop to treat.Eye drip.3 times on the one, each 1 ~ 2, treat 4 weeks.After medication, have 30 routine patients symptomatic's recoveries from illness, 5 routine patients symptomatic are effectively alleviated, and 5 routine patients are invalid.In medication process, have 5 routine patients to occur dysphagia, nausea,vomiting,diarrhea, shed tears, the untoward reaction such as contact dermatitis.With nearly half a year, there are 8 routine Patients on Recurrences.
Contrast two groups: 40 people of this matched group use eye spirit injection to treat.Intramuscular injection; Every day 1 time, each 2ml.Treat 30.After medication, have 30 routine patients symptomatic's recoveries from illness, 4 routine patients symptomatic are effectively alleviated, and 6 routine patients are invalid.In medication process, 5 routine patients are had to go out to lose face to do untoward reaction such as grade.With nearly half a year, there are 5 routine Patients on Recurrences.
Contrast three groups: 40 people of this matched group use An Tai Dian Eye Dropes to treat.Eye drip: every day 2 ~ 4 times, treats 4 weeks.After medication, have 31 routine patients symptomatic's recoveries from illness, 3 routine patients symptomatic are effectively alleviated, and 6 routine patients are invalid.In medication process, after having 7 routine patient's eye drips, have the untoward reaction such as local excitation sense, conjunctival sac secretions increase.With nearly half a year, there are 10 routine Patients on Recurrences.
By contrast, can learn, medicine of the present invention have curative effect fast, effective, have no side effect, the feature such as curative effect is lasting.
Concrete case
Case 1 Wang, female, 65 years old, suffer from senile cataract existing 2 years, Symptoms was the symptom such as photophobia and dazzle, used the cold compress agent of the embodiment of the present invention 1 to treat.Treat every bu morning, noon and afternoon three times, after being cleaned by eye, the cold compress agent of 5g being spread on eye at every turn and carry out washing away for 20 minutes, 7 days is a course for the treatment of, and 3 courses for the treatment of are carried out in treatment.After medication, symptom is fully recovered, and has no side effect.With nearly half a year, not recurrence.
Case 2 Lee, man, 63 years old, suffer from senile cataract one year, Symptoms was the symptom such as visual deterioration, monocular diplopia, used the eye drop of the embodiment of the present invention 2 to treat.Treat every bu morning, noon and afternoon three times, be that the eye drop of 2% is aimed at canthus and carried out dripping a medicine by concentration, each medicine 2-3 that drips drips, and within 7 days, be a course for the treatment of, 3 courses for the treatment of are carried out in treatment.After medication, symptom is fully recovered, and has no side effect.With nearly half a year, not recurrence.
Case 3 grandson, female, 70 years old, suffers from senile cataract and has half a year, and Symptoms, for have the symptoms such as shade at the moment, uses the tablet of the embodiment of the present invention 3 to treat.Treat every bu morning, noon and afternoon three times, each two panels, the dosage of every sheet 0.4g 7 days is a course for the treatment of, and 3 courses for the treatment of are carried out in treatment.After medication, symptom is fully recovered, and has no side effect.With nearly half a year, not recurrence.
Case 4 tunnel, man, 68 years old, suffer from senile cataract existing 2 years, Symptoms was the symptoms such as visual deterioration, used the pill of the embodiment of the present invention 4 to treat.Treat every bu morning, noon and afternoon three times, each ball, every ball is 5g, within 7 days, is a course for the treatment of, and 3 courses for the treatment of are carried out in treatment.After medication, symptom is fully recovered, and has no side effect.With nearly half a year, not recurrence.
The foregoing is only preferred embodiment of the present invention, not in order to limit the present invention, within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.

Claims (3)

1. treat the Chinese medicine composition of senile cataract for one kind, it is characterized in that, in described Chinese medicine composition, the ratio of weight and number of various crude drug is: 10 ~ 25 parts, Semen Persicae, 10 ~ 25 parts, Flos Carthami, Radix Angelicae Sinensis 10 ~ 25 parts, Rhizoma Chuanxiong 10 ~ 25 parts, 10 ~ 25 parts, Radix Rehmanniae Preparata, Borneolum Syntheticum 10 ~ 20 parts, the Radix Paeoniae Alba 10 ~ 25 parts, Fructus Atriplicis Sibiricae 10 ~ 20 parts, Semen Cassiae 10 ~ 20 parts, Fructus Lycii 10 ~ 25 parts, Massa Medicata Fermentata 10 ~ 25 parts, Radix Salviae Miltiorrhizae 10 ~ 25 parts, Fructus Alpiniae Oxyphyllae 10 ~ 25 parts, Fructus Mori 10 ~ 25 parts, Fructus Ligustri Lucidi 10 ~ 25 parts, Flos Chrysanthemi 10 ~ 20 parts, Rhizoma Dioscoreae 10 ~ 20 parts, Sargassum 10 ~ 20 parts, Fructus Schisandrae Chinensis 10 ~ 25 parts, Endothelium Corneum Gigeriae Galli 10 ~ 20 parts, Pericarpium Citri Reticulatae 10 ~ 25 parts, Magnetitum 10 ~ 30 parts, Semen Celosiae 10 ~ 20 parts, Rhizoma Seu Herba Bergeniae 10 ~ 20 parts, 10 ~ 20 parts, shellfish tooth, Flos Eriocauli 10 ~ 20 parts and Faeces Vespertilionis 10 ~ 20 parts,
The dosage form of described Chinese medicine composition is cold compress agent, and described preparation process is: first the described crude drug except Borneolum Syntheticum is ground into coarse powder, then pulverizes further, crosses 120 mesh sieves, collects and obtain fine powder a by the fine powder of 120 mesh sieves; Again the coarse powder not by 120 mesh sieves is dropped into multi-function extractor and extract twice, first time adds 4-6 times amount soak by water 1-2 hour, and second time adds 3-5 times amount soak by water 1-2 hour, merges twice decocting liquid, filters to get filtrate; Filtrate heating is concentrated into pasty state, puts into after 80 DEG C, baking oven is dried and cool, grind to form fine powder b, for subsequent use after fine powder a is mixed with fine powder b; Then by Borneolum Syntheticum extraction by steam distillation, crystal c is obtained; Added by crystal c in the mixture of fine powder a and fine powder b, mixing adds qs glycerin, glycerol addition be the 2-8 of fine powder mixture gross mass doubly, furnishing paste, loads in colored bottle after sterilization, and it is for subsequent use to put into refrigerator-freezer 0 DEG C-4 DEG C storage;
Or the dosage form of described Chinese medicine composition is eye drop, and described preparation process is:
A, get described crude drug and add water extraction 2 times, first time adds 4-6 times amount soak by water 1-2 hour, and second time adds 3-5 times amount soak by water 1-2 hour, 2 extracting solution are merged, filter, when concentrating under reduced pressure obtains 80 DEG C, relative density is the extractum 1 of 1.04 ~ 1.10, and medicinal residues are for subsequent use;
B, medicinal residues are added 60-90% soak with ethanol 0.5-1.5 hour, extract twice, each 1-2 hour, merge extractive liquid, filters, concentrated, 80-160 order filters, and 6000-10000 rev/min centrifugal, gets supernatant, through the ultrafiltration post ultrafiltration that the molecular weight that dams is 5000-10000, when ultrafiltrate concentrating under reduced pressure relative density is 60 DEG C 1.25 extractum 2;
C, extractum 1 and extractum 2 to be mixed, add sodium chloride and the 60-80 distilled water doubly of 0.06% of mixing extractum gross mass, and to add concentration be that 4% sodium hydroxide solution regulates pH to be 6.0-7.0, add 0.2% active carbon again and boil 10 minutes, filter, subpackage, sterilizing, obtains eye drop.
2. the Chinese medicine composition for the treatment of senile cataract according to claim 1, it is characterized in that, in described Chinese medicine composition, the ratio of weight and number of various crude drug is: 10 ~ 25 parts, Semen Persicae, 15 ~ 25 parts, Flos Carthami, Radix Angelicae Sinensis 10 ~ 25 parts, Rhizoma Chuanxiong 20 ~ 25 parts, 15 ~ 25 parts, Radix Rehmanniae Preparata, Borneolum Syntheticum 10 ~ 20 parts, the Radix Paeoniae Alba 10 ~ 25 parts, Fructus Atriplicis Sibiricae 10 ~ 20 parts, Semen Cassiae 10 ~ 20 parts, Fructus Lycii 20 ~ 25 parts, Massa Medicata Fermentata 20 ~ 25 parts, Radix Salviae Miltiorrhizae 10 ~ 25 parts, Fructus Alpiniae Oxyphyllae 10 ~ 15 parts, Fructus Mori 10 ~ 20 parts, Fructus Ligustri Lucidi 10 ~ 20 parts, Flos Chrysanthemi 10 ~ 20 parts, Rhizoma Dioscoreae 10 ~ 15 parts, Sargassum 10 ~ 15 parts, Fructus Schisandrae Chinensis 10 ~ 20 parts, Endothelium Corneum Gigeriae Galli 10 ~ 15 parts, Pericarpium Citri Reticulatae 10 ~ 15 parts, Magnetitum 10 ~ 20 parts, Semen Celosiae 15 ~ 20 parts, Rhizoma Seu Herba Bergeniae 10 ~ 20 parts, 10 ~ 20 parts, shellfish tooth, Flos Eriocauli 10 ~ 15 parts and Faeces Vespertilionis 10 ~ 20 parts.
3. the Chinese medicine composition for the treatment of senile cataract according to claim 1, it is characterized in that, in described Chinese medicine composition, the ratio of weight and number of various crude drug is: 10 ~ 20 parts, Semen Persicae, 10 ~ 15 parts, Flos Carthami, Radix Angelicae Sinensis 10 ~ 20 parts, Rhizoma Chuanxiong 10 ~ 20 parts, 10 ~ 20 parts, Radix Rehmanniae Preparata, Borneolum Syntheticum 10 ~ 15 parts, the Radix Paeoniae Alba 10 ~ 15 parts, Fructus Atriplicis Sibiricae 10 ~ 15 parts, Semen Cassiae 10 ~ 15 parts, Fructus Lycii 10 ~ 20 parts, Massa Medicata Fermentata 10 ~ 20 parts, Radix Salviae Miltiorrhizae 10 ~ 20 parts, Fructus Alpiniae Oxyphyllae 10 ~ 25 parts, Fructus Mori 20 ~ 25 parts, Fructus Ligustri Lucidi 10 ~ 25 parts, Flos Chrysanthemi 10 ~ 15 parts, Rhizoma Dioscoreae 10 ~ 20 parts, Sargassum 10 ~ 20 parts, Fructus Schisandrae Chinensis 20 ~ 25 parts, Endothelium Corneum Gigeriae Galli 15 ~ 20 parts, Pericarpium Citri Reticulatae 15 ~ 25 parts, Magnetitum 20 ~ 30 parts, Semen Celosiae 10 ~ 20 parts, Rhizoma Seu Herba Bergeniae 10 ~ 15 parts, 10 ~ 15 parts, shellfish tooth, Flos Eriocauli 10 ~ 20 parts and Faeces Vespertilionis 10 ~ 15 parts.
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CN101972340B (en) * 2010-10-08 2012-01-25 张继成 Traditional Chinese medicine composition for tonifying liver and improving eyesight
CN102784301B (en) * 2012-07-18 2013-12-11 黄平县润发药业农民专业合作社 Traditional Chinese medicine treating early cataract and its preparation method
CN102949540A (en) * 2012-11-20 2013-03-06 孙斌 Traditional Chinese medicinal composite for treating cataract

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