CN115176953A - Mushroom polysaccharide compatibility capable of invigorating spleen, replenishing qi, tonifying deficiency, consolidating constitution and assisting in resisting tumors - Google Patents
Mushroom polysaccharide compatibility capable of invigorating spleen, replenishing qi, tonifying deficiency, consolidating constitution and assisting in resisting tumors Download PDFInfo
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- CN115176953A CN115176953A CN202110375028.3A CN202110375028A CN115176953A CN 115176953 A CN115176953 A CN 115176953A CN 202110375028 A CN202110375028 A CN 202110375028A CN 115176953 A CN115176953 A CN 115176953A
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- grifola frondosa
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- cordyceps militaris
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/385—Concentrates of non-alcoholic beverages
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/20—Reducing nutritive value; Dietetic products with reduced nutritive value
- A23L33/21—Addition of substantially indigestible substances, e.g. dietary fibres
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Mycology (AREA)
- Molecular Biology (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention discloses a mushroom polysaccharide compatibility for tonifying spleen and qi, tonifying deficiency and consolidating constitution and assisting in resisting tumors, which is prepared from the following raw materials in parts by weight: 30-90 parts of grifola frondosa extract, 10-50 parts of cordyceps militaris powder, 5-90 parts of yeast beta glucan and 5-60 parts of xylo-oligosaccharide; the invention extracts active ingredients from natural mushroom as a raw material, and maximizes the function of promoting nutrition and health care on the basis of nutrition assistance; the health-care food has the functions of recovering chronic diseases, is safe to food and can be taken for a long time, and the chronic diseases are easily conditioned by food therapy in daily life, so that the pain of hospital treatment is reduced, and more chronic patients have the health and happiness of dignity and prolonging life; the invention has the advantages of oxidation resistance, immunity improvement and toxic and side effects of radiotherapy and chemotherapy.
Description
Technical Field
The invention relates to the technical field of beverages, in particular to a compatibility of mushroom polysaccharides for strengthening spleen, replenishing qi, tonifying deficiency, consolidating the constitution and assisting in resisting tumors.
Background
The beverage is a liquid for people or livestock, is packaged quantitatively and can be directly drunk or brewed by water according to a certain proportion, the ethanol content (mass component) is not more than 0.5 percent, the beverage can also be divided into beverage thick pulp or solid form, and the beverage has the functions of quenching thirst, supplementing energy and the like. But the beverage in the market generally does not have the function of maximally promoting nutrition and health on the basis of nutrition assistance.
Disclosure of Invention
The invention aims to provide a mushroom polysaccharide compatibility for strengthening spleen and replenishing qi, tonifying deficiency and consolidating foundation and assisting in resisting tumors so as to solve the problems in the background technology.
In order to achieve the purpose, the invention provides the following technical scheme:
the compatibility of the mushroom polysaccharide for invigorating spleen and replenishing qi, tonifying deficiency and consolidating the constitution and assisting in resisting tumors comprises the following raw materials in parts by weight: 30-90 parts of grifola frondosa extract, 10-50 parts of cordyceps militaris powder, 5-90 parts of yeast beta glucan and 5-60 parts of xylo-oligosaccharide.
As a further scheme of the invention: the formula of the functional grifola frondosa composite solid beverage is composed of the following raw materials in parts by weight: 35-85 parts of grifola frondosa extract, 15-45 parts of cordyceps militaris powder, 10-85 parts of yeast beta glucan and 10-55 parts of xylo-oligosaccharide.
As a still further scheme of the invention: the formula of the functional grifola frondosa composite solid beverage is composed of the following raw materials in parts by weight: 60 parts of grifola frondosa extract, 30 parts of cordyceps militaris powder, 48 parts of yeast beta glucan and 33 parts of xylo-oligosaccharide.
As a still further scheme of the invention: the extraction process of the grifola frondosa extract comprises the following steps: 1) Extracting the fine powder of Grifola frondosa fruiting body or Grifola frondosa dry mycelium with microwave-assisted hot water at pH of 6, and centrifuging at 6000-10000rpm to obtain Grifola frondosa polysaccharide extract; 2) And (2) concentrating the supernatant obtained in the step 1) in vacuum, adding a proper amount of ethanol, standing overnight, centrifuging, taking the precipitate, and drying.
As a still further scheme of the invention: the cordyceps militaris powder is 200-mesh cordyceps militaris powder.
Compared with the prior art, the invention has the beneficial effects that:
the invention takes natural mushroom as raw material to extract active ingredients, and maximizes the function of promoting nutrition and health care on the basis of nutrition assistance; the health-care food not only has the function of recovering chronic diseases, but also has the advantages of food safety, long-term taking, easy dietotherapy conditioning of chronic diseases in daily life, reduction of the treatment pain of hospitals, and healthy and happy life-prolonging of more chronic patients; the invention has the advantages of oxidation resistance, immunity improvement and toxic and side effects of radiotherapy and chemotherapy.
Detailed Description
The technical solution of the present invention will be described in further detail with reference to specific embodiments.
Example 1
The compatibility of the mushroom polysaccharide for invigorating spleen, replenishing qi, tonifying deficiency, consolidating constitution and assisting in resisting tumors comprises the following raw materials in parts by weight: 30 parts of grifola frondosa extract, 10 parts of cordyceps militaris powder, 5 parts of yeast beta glucan and 5 parts of xylo-oligosaccharide.
The extraction process of the grifola frondosa extract comprises the following steps: 1) Extracting the fine powder of Grifola frondosa fruiting body or Grifola frondosa dry mycelium with microwave-assisted hot water at pH of 6, and centrifuging at 6000-10000rpm to obtain Grifola frondosa polysaccharide extract; 2) And (2) concentrating the supernatant obtained in the step 1) in vacuum, adding a proper amount of ethanol, standing overnight, centrifuging, taking the precipitate, and drying.
The cordyceps militaris powder is 200-mesh cordyceps militaris powder.
Example 2
The compatibility of the mushroom polysaccharide for invigorating spleen and replenishing qi, tonifying deficiency and consolidating the constitution and assisting in resisting tumors comprises the following raw materials in parts by weight: grifola frondosa extract 90, cordyceps militaris powder 50, yeast beta glucan 90 and xylo-oligosaccharide 60.
The extraction process of the grifola frondosa extract comprises the following steps: 1) Extracting Grifola frondosa sporophore or Grifola frondosa dry mycelium fine powder with microwave-assisted hot water at pH of 6, and centrifuging at 6000-10000rpm to obtain Grifola frondosa polysaccharide extract; 2) And (2) concentrating the supernatant obtained in the step 1) in vacuum, adding a proper amount of ethanol, standing overnight, centrifuging, taking the precipitate, and drying.
The cordyceps militaris powder is 200-mesh cordyceps militaris powder.
Example 3
The compatibility of the mushroom polysaccharide for invigorating spleen and replenishing qi, tonifying deficiency and consolidating the constitution and assisting in resisting tumors comprises the following raw materials in parts by weight: 60 parts of grifola frondosa extract, 30 parts of cordyceps militaris powder, 48 parts of yeast beta glucan and 33 parts of xylo-oligosaccharide.
The extraction process of the grifola frondosa extract comprises the following steps: 1) Extracting the fine powder of Grifola frondosa fruiting body or Grifola frondosa dry mycelium with microwave-assisted hot water at pH of 6, and centrifuging at 6000-10000rpm to obtain Grifola frondosa polysaccharide extract; 2) And (2) concentrating the supernatant obtained in the step 1) in vacuum, adding a proper amount of ethanol, standing overnight, centrifuging, taking the precipitate, and drying.
The cordyceps militaris powder is 200-mesh cordyceps militaris powder.
Example 4
The compatibility of the mushroom polysaccharide for invigorating spleen and replenishing qi, tonifying deficiency and consolidating the constitution and assisting in resisting tumors comprises the following raw materials in parts by weight: 35 parts of grifola frondosa extract, 15 parts of cordyceps militaris powder, 10 parts of yeast beta glucan and 10 parts of xylo-oligosaccharide.
The extraction process of the grifola frondosa extract comprises the following steps: 1) Extracting the fine powder of Grifola frondosa fruiting body or Grifola frondosa dry mycelium with microwave-assisted hot water at pH of 6, and centrifuging at 6000-10000rpm to obtain Grifola frondosa polysaccharide extract; 2) And (2) concentrating the supernatant obtained in the step 1) in vacuum, adding a proper amount of ethanol, standing overnight, centrifuging, taking the precipitate, and drying.
The cordyceps militaris powder is 200-mesh cordyceps militaris powder.
Example 5
The compatibility of the mushroom polysaccharide for invigorating spleen and replenishing qi, tonifying deficiency and consolidating the constitution and assisting in resisting tumors comprises the following raw materials in parts by weight: grifola frondosa extract 85, cordyceps militaris powder 45, yeast beta glucan 85 and xylo-oligosaccharide 55.
The extraction process of the grifola frondosa extract comprises the following steps: 1) Extracting Grifola frondosa sporophore or Grifola frondosa dry mycelium fine powder with microwave-assisted hot water at pH of 6, and centrifuging at 6000-10000rpm to obtain Grifola frondosa polysaccharide extract; 2) And (2) concentrating the supernatant obtained in the step 1) in vacuum, adding a proper amount of ethanol, standing overnight, centrifuging, taking the precipitate, and drying.
The cordyceps militaris powder is 200-mesh cordyceps militaris powder.
The pharmacology of the invention is as follows:
grifola frondosa is a large edible fungus, and the active ingredient D-fraction (combination of active glucan and protein) of the Grifola frondosa contains glucan combined with beta- (1-6) as a main chain and beta- (1-3) as side chains and active glucan combined with beta- (1-3) as a main chain and beta- (1-6) as side chains to form a three-dimensional structure, so that the Grifola frondosa is the most valuable core active ingredient, and experiments prove that the active substances can obviously inhibit the growth of tumors by activating the immune function.
It is commonly used in clinic:
replenishing qi to invigorate the spleen, tonifying deficiency to strengthen body resistance, and consolidating constitution. Regulating organism balance in two directions, and enhancing organism immunity.
2. The traditional Chinese medicine composition has the effects of dredging qi activity, adjusting the function of internal organs, and remarkably improving the spleen-qi deficiency and the spleen-yang deficiency of patients.
3. Can be used for treating leukopenia and hemoglobin reduction caused by hypofunction, overfatigue or unknown reasons
4. Can be used for recovering operation or damaged body function. Can enhance body resistance, promote wound and fracture healing, and promote body function to recover normal.
5. Is suitable for treating various chronic viral hepatitis, removing toxic substance, relieving pain, and reducing transaminase.
6. Can be used for reducing adverse side effects of radiotherapy and chemotherapy during radiotherapy for tumor patients, and antagonizing leukocyte decrease caused by immunosuppressant.
2. Beta glucan: yeasts are of fungal origin, being of the same type as edible fungi. beta-1,3/1,6-D-glucan is extracted and purified by Saccharomyces cerevisiae (Saccharomyces cerevisiae) by a patent process, and the molecular weight is 800-1000KD
The famous enterprises for making nutrients include: the Anli, wandashan, tangchen Beijian and the like all have the contribution of beta glucan on the nutritional protein powder of women in the convalescent period, children, old people and the like, can quickly improve the immunity and are far away from the upper respiratory tract infection and pneumonia caused by cold.
Yeast beta glucan provides multiple functions:
clinical population study: upper respiratory tract infection and diabetes
Multiple clinical animal studies: immunity enhancing, radioprotective, antiinfectious, radioprotective, intestinal regulating, blood lipid regulating, antitumor, and antiviral effects
3. The cordyceps militaris contains various nutritional functions:
cordycepin, cordycepic acid and cordyceps polysaccharide are special substances of cordyceps sinensis and are main indexes of special efficacy of cordyceps sinensis. It is precisely these indexes that the north aweto growing under the condition of artificial environment is higher than that growing under the natural condition. The contents of artificially cultured Cordyceps militaris protein, amino acids, vitamins, etc. reach or exceed the level of natural Cordyceps. The research proves that the artificially cultured cordyceps militaris has the same clinical effects as natural cordyceps militaris, can also regulate the functions of the whole body, improve the immunity, enhance the phagocytic function of macrophages and promote the formation of antibodies, and mainly has the effects of protecting the lung, tonifying the kidney, nourishing the liver, relieving cough, relieving asthma, eliminating phlegm, moistening the skin, preventing wrinkles and aging, resisting bacteria, resisting inflammation, calming, expanding blood vessels, reducing blood pressure, reducing blood sugar, resisting fatigue, resisting oxygen deficiency and the like.
4. Unique performance of xylo-oligosaccharide
Xylo-oligosaccharide is difficult to be decomposed by human digestive enzyme. Digestion experiments with saliva, gastric juice, pancreatic juice and intestinal enzyme juice showed that: the xylo-oligosaccharide can not be decomposed by various digestive juices, the energy value of the xylo-oligosaccharide is almost zero, the xylo-oligosaccharide does not affect the blood sugar concentration, does not increase the insulin level in blood sugar, and does not form fat deposition, so the xylo-oligosaccharide can play a role in low-energy food, and the xylo-oligosaccharide can meet the requirements of people who like sweets and worry about diabetes and obesity to the maximum extent, so that the xylo-oligosaccharide can be eaten by diabetes patients, obesity patients and hypoglycemia patients at ease. Xylo-oligosaccharide is one of the varieties with the strongest function for proliferating bifidobacteria in polymeric saccharides, has the efficacy which is about 20 times that of other polymeric saccharides, and has no enzyme for hydrolyzing xylo-oligosaccharide in the gastrointestinal tract of a human body, so that xylo-oligosaccharide can be directly introduced into the large intestine to be preferentially utilized by bifidobacteria, and can promote the proliferation of the bifidobacteria and simultaneously generate a plurality of organic acids. The pH value of the intestinal tract is reduced, the growth of harmful bacteria is inhibited, and the probiotics are proliferated in a large amount in the intestinal tract to achieve the health-care effect, which is the mysterious place of the health care of the xylooligosaccharide. The xylo-oligosaccharide can obviously proliferate bifidobacterium in large quantity, thereby achieving the purpose of making the probiotics become intestinal dominant bacteria and eliminating harmful bacteria.
Nutritious and health promoting effects of xylooligosaccharide
1. Reduction of toxic fermentation products and production of harmful bacterial enzymes
Human in vivo and in vitro fecal culture experiments showed that in vivo within 3 weeks of ingestion, 44.6% production of toxic fermentation products and 40.9% production of harmful bacterial enzymes could be reduced.
2. Inhibiting pathogenic bacteria and diarrhea
The xylo-oligosaccharide has strong adsorption force on pathogenic bacteria, such as escherichia coli, enteritis phylum bacteria, klebsiella pneumoniae, aeromonas hydrophila and the like can be adsorbed on the xylo-oligosaccharide, and the xylo-oligosaccharide can carry the attached pathogenic bacteria to be discharged out of the body through the intestinal tract because the xylo-oligosaccharide is not degraded by digestive enzymes in the intestinal tract, thereby preventing diseases from being clustered in the intestinal tract and achieving the purpose of preventing diarrhea.
3. Preventing constipation
The bifidobacterium uses xylo-oligosaccharide to produce a large amount of short chain fatty acid; can stimulate intestinal peristalsis, increase stool wetness, and maintain a certain osmotic pressure, thereby preventing constipation.
4. Protecting liver function
The intake of xylo-oligosaccharide can reduce the formation of toxic metabolites and greatly reduce the burden of the liver to decompose toxins.
5. Reducing serum cholesterol
The total serum cholesterol can be reduced by 20-50dl after taking xylo-oligosaccharide for 2 weeks to 3 months. It also can increase the ratio of total cholesterol in female serum to total cholesterol.
6. Lowering blood pressure
The study showed that 46 hyperlipidemia patients all had a drop in diastolic flattening of 799.8Pa (6 mmHg) after 5 weeks of xylo-oligosaccharide intake. The results show that the high and low diastolic pressure of human beings are obviously in a negative correlation with the ratio of bifidobacteria to the total bacteria number in the feces.
7. Can enhance immunity and reduce tumor incidence.
A large number of test results show that the bifidobacterium can play a role in inhibiting tumors by mass propagation in intestinal tracts. The inhibition is due to the cells, cell wall components and extracellular secretion of Bacillus bifidus, and improves immunity.
According to years of product research and development practical experience, the food is continuously innovated in the original market clinical practice, and the original novel food resources with clear functions and safe eating are excavated to be used as the formula of the product, so that the ideal nutrition and health care function is achieved, the slow disease rehabilitation effect is achieved, the food is safe and can be taken for a long time, the chronic diseases are easily conditioned by food therapy in daily life, the pain of hospital treatment is reduced, and more chronic patients have the health and happiness of dignity and prolonging life.
While the preferred embodiments of the present invention have been described in detail, the present invention is not limited to the above embodiments, and various changes can be made without departing from the spirit of the present invention within the knowledge of those skilled in the art.
Claims (5)
1. The compatibility of the mushroom polysaccharide for invigorating spleen, replenishing qi, tonifying deficiency, consolidating constitution and assisting in resisting tumors is characterized by comprising the following raw materials in parts by weight: 30-90 parts of grifola frondosa extract, 10-50 parts of cordyceps militaris powder, 5-90 parts of yeast beta glucan and 5-60 parts of xylo-oligosaccharide.
2. The compatibility of the mushroom polysaccharide for invigorating spleen, replenishing qi, tonifying deficiency, consolidating constitution and assisting in resisting tumors according to claim 1, wherein the formula of the functional grifola frondosa composite solid beverage comprises the following raw materials in parts by weight: 35-85 parts of grifola frondosa extract, 15-45 parts of cordyceps militaris powder, 10-85 parts of yeast beta glucan and 10-55 parts of xylo-oligosaccharide.
3. The compatibility of mushroom polysaccharide for invigorating spleen and replenishing qi, tonifying deficiency and consolidating constitution as well as assisting in resisting tumors according to claim 1 is characterized in that the formula of the functional grifola frondosa composite solid beverage comprises the following raw materials in parts by weight: 60 parts of grifola frondosa extract, 30 parts of cordyceps militaris powder, 48 parts of yeast beta glucan and 33 parts of xylo-oligosaccharide.
4. The compatibility of mushroom polysaccharides for invigorating spleen and replenishing qi, tonifying deficiency and consolidating constitution as well as assisting in resisting tumors according to claim 1, wherein the extraction process of the grifola frondosa extract comprises the following steps: 1) Extracting the fine powder of Grifola frondosa fruiting body or Grifola frondosa dry mycelium with microwave-assisted hot water at pH of 6, and centrifuging at 6000-10000rpm to obtain Grifola frondosa polysaccharide extract; 2) And (2) concentrating the supernatant obtained in the step 1) in vacuum, adding a proper amount of ethanol, standing overnight, centrifuging, taking the precipitate, and drying.
5. The mushroom polysaccharide combination for invigorating spleen, replenishing qi, tonifying deficiency, consolidating constitution and assisting in anti-tumor according to claim 1, wherein the cordyceps militaris powder is 200-mesh cordyceps militaris powder.
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104544431A (en) * | 2014-12-26 | 2015-04-29 | 山东明仁福瑞达制药股份有限公司 | Grifolafrondosa and cordyceps militaris drink |
| CN108991332A (en) * | 2018-10-11 | 2018-12-14 | 常建良 | A kind of grifola frondosus, Cordyceps militaris edible mushroom solid beverage |
| CN110881602A (en) * | 2019-12-09 | 2020-03-17 | 李维鸽 | Grifola frondosa and cordyceps militaris edible fungus solid beverage |
| CN111011833A (en) * | 2019-12-23 | 2020-04-17 | 惠州市润树农业科技有限公司 | Processing technology of ash tree pollen and ash tree pollen solid beverage |
-
2021
- 2021-04-02 CN CN202110375028.3A patent/CN115176953A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104544431A (en) * | 2014-12-26 | 2015-04-29 | 山东明仁福瑞达制药股份有限公司 | Grifolafrondosa and cordyceps militaris drink |
| CN108991332A (en) * | 2018-10-11 | 2018-12-14 | 常建良 | A kind of grifola frondosus, Cordyceps militaris edible mushroom solid beverage |
| CN110881602A (en) * | 2019-12-09 | 2020-03-17 | 李维鸽 | Grifola frondosa and cordyceps militaris edible fungus solid beverage |
| CN111011833A (en) * | 2019-12-23 | 2020-04-17 | 惠州市润树农业科技有限公司 | Processing technology of ash tree pollen and ash tree pollen solid beverage |
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Application publication date: 20221014 |