CN104906140A - Donkey-hide gelatin, a preparation method and associated equipment - Google Patents

Abstract

The invention relates to donkey-hide gelatin, a preparation method and associated equipment, which belong to the deep development of rare herbal donkey-hide gelatins, the technology for replacing materials of the rare herbal donkey-hide gelatins and relevant products of the rare herbal donkey-hide gelatins in the sustainable utilization field of Chinese herbal resources. According to the method, any one or multiple or all of litsea cubeba oil, lucid ganoderma, mushroom, hericium erinaceus, trametes robiniophila Murr, poria cocos, polyporus umbellatus, rainbow conk, marasmius androsaceus, armillaria mellea, false armillaria mellea, cordyceps sinensis, cordyceps militaris, tremella fuciformis, flammulina velutipes, edible fungus, grifola frondosa, gloeostereum incarnatum, schizophyllum commune, fomitopsis pinicola, cordyceps cephalosporium, paecilomyces hepialid, cordyceps gunnii penicillium, litsea cubeba, bamboo fungus, phellinus igniarius and edible fungus are added into water for peel soaking, peel removing, peel cutting, peel washing, complete peel removing and gelatin juice extraction during the production process of the Chinese herbal gelatin. The method has the most obvious characteristic that the problems that the donkey-hide gelatin material is deficient, the putrefactive odor is dispersive by the donkey-hide gelatin material during the production of the donkey-hide gelatin and the finished donkey-hide gelatin product is poor in taste are solved.

Description

A kind of Colla Corii Asini and preparation method thereof and relevant device

Technical field

The invention belongs to Chinese herbal medicine industry, especially belong to the deep level development of rare medicinal herbs Colla Corii Asini in natural resources of Chinese medicinal materials sustainable use field and the technology of its raw material substitution and Related product thereof.

Background technology

Colla Corii Asini production capacity expands, and meets the whole world pair chinese medicinethe demand of Colla Corii Asini, but bring new problem simultaneously--Colla Corii Asini is produced and is faced the awkward situation that there is lack of raw materials.Donkey skin is the primary raw material of processing Colla Corii Asini, accounts for more than 98% of its material rate.China donkey mainly originates in a few province of the northern areas such as northeast, North China, northwest, the rare cultivation in southern area.Peasant thinks that foster donkey benefit is good not as cowboying, sheep, pig more, does not form cultivation custom, only has the multiplex donkey in mountain area and remote countryside to do short-distance transport or mill rice and flour, and improving constantly along with rural area mechanization degree, donkey quantity also glides year by year.According to statistics, domestic donkey skin resource declines with the speed of 20% every year in recent years.

At present, donkey skin shortage of resources has become the large bottleneck that restriction Colla Corii Asini industry is accelerated development.According to investigation, China's donkey resource is sharply declining, and donkey is slaughtered family and reduces year by year, the competition of donkey skin.Cattle, sheep are defined as leading aquaculture industry by major part province, and also do not hear which place makes the planning that donkey is supported in development, donkey breeding stock is on a declining curve.Why can support donkey industry atrophy step by step? according to investigations, following several reasons are mainly contained.The first, along with the increase year by year of farmers' income, the peasant of plains region has replaced to tractor, tricycle using original generations as the donkey of animal power, the vehicles and donkey cart at leisure.The second, the economic benefit of supporting donkey is high not as good as sheep raising, cowboying and other animal husbandry, and take effect slow, the cultivation enthusiasm of peasant is not high.3rd, the growth cycle of donkey is long, breeding potential is low, and local government does not also treat as the industry of agro based economic development, and current raising is in the state of nature cultivation and national customs substantially.4th, the donkey breeding cycle is long, butchers family under the ordering about of profit, butchers, cause donkey breeding stock sharply to decline like, sex of all ages to local donkey extinction.5th, over the past two years, Carnis Equi Asini price is per ton hovered between 13500-14000 unit, and Carnis Equi Asini price at a low tide is difficult to promote the development of donkey aquaculture industry.

Be necessary to seek a kind of resource that can substitute donkey skin to reduce the production cost of Colla Corii Asini, and synchronously profound development and utilization carried out to Colla Corii Asini.

Summary of the invention

Goal of the invention: the equipment that a kind of production method of Colla Corii Asini and supporting product and this product of production are provided.

Realize the technical scheme of goal of the invention:

1. when producing Chinese medicine colloid, generally with the skin of animal, bone, first, angle is primary raw material, uses sugar in right amount, oils and fats, and wine is adjuvant, make dry gluey, granule, liquid, the oral preparations of powdery, the present invention is the bubble skin in production procedure, unhairing, cut skin, wash skin, to pick up skin, extract in glue juice water and add Ganoderma, Lentinus Edodes, Hericium erinaceus (Bull. Ex Fr.) Pers., Chinese scholartree bolt bacterium, Poria, Polyporus, Coriolous Dersicolor (Fr.) Quel, Marasmius androsaceus (L.ex Fr.) Fr., armillaria mellea, Armillariella tabescens, Cordyceps, Cordyceps militaris (L.) Link., Tremella, Flammulina velutiper (Fr.) Sing, Auricularia, Grifola frondosa, Pleurotus ulmarius (Bullex Franch) Quel fungus, Schizophyllum commune Franch．, red edge intends shelf fungus, cephalosporium sinensis, peacilomyce hepiahi bacterium, Paecilomyces gunnii, Fructus Litseae, Caulis Bambusae In Taeniam, Phellinus igniarius (L. ex Fr.) Quel., any one composition in Auricularia, or any two kinds of compositions, or any three kinds of compositions, or any four kinds of compositions, or any five kinds of compositions, or any six kinds of compositions, or any seven kinds of compositions, or any eight kinds of compositions, or any nine kinds of compositions, or any ten kinds of compositions, or any 11 kinds of compositions, or any 12 kinds of compositions, or any 13 kinds of compositions, or any 14 kinds of compositions, or any 15 kinds of compositions, or any 16 kinds of compositions, or any 17 kinds of compositions, or any 18 kinds of compositions, or any 19 kinds of compositions, or any 20 kinds of compositions, or any 21 kinds of compositions, or any 22 kinds of compositions, or whole composition.

2. add feeding medicinal fungus to providing in the animal feeding of Chinese medicine colloid raw material, or/and some Chinese herbal medicine, as:

add and feed Ganoderma, Lentinus Edodes, Hericium erinaceus (Bull. Ex Fr.) Pers., Chinese scholartree bolt bacterium, Poria, Polyporus, Coriolous Dersicolor (Fr.) Quel, Marasmius androsaceus (L.ex Fr.) Fr., armillaria mellea, Armillariella tabescens, Cordyceps, Cordyceps militaris (L.) Link., Tremella, Flammulina velutiper (Fr.) Sing, Auricularia, Grifola frondosa, Pleurotus ulmarius (Bullex Franch) Quel fungus, Schizophyllum commune Franch．, red edge intends shelf fungus, cephalosporium sinensis, peacilomyce hepiahi bacterium, Paecilomyces gunnii, Omphalia, Caulis Bambusae In Taeniam, Phellinus igniarius (L. ex Fr.) Quel., any one composition in Auricularia, or any two kinds of compositions, or any three kinds of compositions, or any four kinds of compositions, or any five kinds of compositions, or any six kinds of compositions, or any seven kinds of compositions, or any eight kinds of compositions, or any nine kinds of compositions, or any ten kinds of compositions, or any 11 kinds of compositions, or any 12 kinds of compositions, or any 13 kinds of compositions, or any 14 kinds of compositions, or any 15 kinds of compositions, or any 16 kinds of compositions, or any 17 kinds of compositions, or any 18 kinds of compositions, or any 19 kinds of compositions, or any 20 kinds of compositions, or any 21 kinds of compositions, or any 22 kinds of compositions, or aforementioned whole composition, or

add and feed Fructus Crataegi, Massa Medicata Fermentata, Fructus Hordei Germinatus, Fructus Setariae Germinatus, Radix Ginseng, Radix Panacis Quinquefolii, Radix Codonopsis, the Radix Astragali, Rhizoma Dioscoreae, Radix Angelicae Sinensis, Radix Rehmanniae, Radix Polygoni Multiflori, Arillus Longan, Radix Morindae Officinalis, Herba Cistanches, Rhizoma Curculiginis, the Cortex Eucommiae, Radix Dipsaci, Rhizoma Cibotii, Rhizoma Drynariae, Fructus Psoraleae, Fructus Alpiniae Oxyphyllae, Semen Juglandis, Semen Cuscutae, Semen Astragali Complanati, Herba Cynomorii, fragrant-flowered garlic, Actinolitum, Radix Adenophorae (Radix Glehniae), Radix Ophiopogonis, Radix Asparagi, Herba Dendrobii, Rhizoma Polygonati Odorati, Rhizoma Polygonati, Bulbus Lilii, Fructus Lycii, Fructus Mori, Herba Ecliptae, Fructus Ligustri Lucidi, Semen Sesami Nigrum, Herba Leonuri, Fructus Litseae, Folium Artemisiae Argyi, Herba Limonii Gmelinii, any one composition in Herb Gynostemmae Pentaphylli, or any two kinds of compositions, or any three kinds of compositions, or any four kinds of compositions, or any five kinds of compositions, or any six kinds of compositions, or any seven kinds of compositions, or any eight kinds of compositions, or any nine kinds of compositions, or any ten kinds of compositions, or any 11 kinds of compositions, or any 12 kinds of compositions, or any 13 kinds of compositions, or any 14 kinds of compositions, or any 15 kinds of compositions, or any 16 kinds of compositions, or any 17 kinds of compositions, or any 18 kinds of compositions, or any 19 kinds of compositions, or any 20 kinds of compositions, or any 21 kinds of compositions, or any 22 kinds of compositions, or any 23 kinds of compositions, or any 24 kinds of compositions, or any 25 kinds of compositions, or any 26 kinds of compositions, or any 27 kinds of compositions, or any 28 kinds of compositions, or any 29 kinds of compositions, or any 30 kinds of compositions, or any 31 kinds of compositions, or any 32 kinds of compositions, or any 33 kinds of compositions, or any 34 kinds of compositions, or any 35 kinds of compositions, or any 36 kinds of compositions, or any 37 kinds of compositions, or any 38 kinds of compositions, or any 39 kinds of compositions, or any 40 kinds of compositions, or any 41 kinds of compositions, or any 42 kinds of compositions, any 43 kinds of compositions, any 44 kinds of compositions, or whole composition, or

add feed aforementioned in any one, or several, or all after coordinate again in any one, or several, or all.

3. on the make the bubble skin of medicine colloid, unhairing, cut skin, wash skin, skin of picking up, extract the chitting piece adding grass in glue juice water, as any one composition in Fructus Setariae Germinatus, Fructus Hordei Germinatus, Fructus Setariae Germinatus, or two kinds, or whole compositions.Certainly, also can only in bubble skin, unhairing, cut skin, wash skin, skin of picking up, extract in glue juice water any one, or several flow process with the chitting piece adding grass in water, be recommended in bubble skin and extraction glue juice water and add.

4. pair produce the bubble skin of Chinese medicine colloid, unhairing, cut skin, wash skin, skin of picking up, extract glue juice carry out electric field/magnetization treatment with water, steam.

5., when producing colloid, use quicklime, Gypsum Fibrosum preparata as the thermal source extracting glue juice, concentrated glue juice.

6. when producing the thermal source heat resource equipment container that colloid uses quicklime, Gypsum Fibrosum preparata as extraction glue juice, concentrated glue juice, can to this heat resource equipment container pack heat-insulating heat-preserving material.

7., in the adjuvant oils and fats used when producing Chinese medicine colloid, add litsea cubeba oil, the ratio of adding can be whole, also can be part.

8. when producing Chinese medicine colloid, by animals' reproduction organ as one of raw materials for production.

9. by the kidney of animal domestic animal, birds, penis, as Ren caprae seu ovis Testis Et penis Caprae seu Ovis, Testis et Pentis Canis Penis et testis canitis, Ren Tigris Penis et testis Tigris, leopard kidney leopard whip, Testis Et penis Equi Testis Et penis Equi, Testis et penis Gallus domesticus, Ren Bovis seu Bubali Testis Et penis Bovis seu Bubali, Penis et testis sus domestica, Testis et penis callorhini, Penis et testis cervi Penis et testis cervi.

10. produce in the Colla Corii Asini process made for primary raw material with donkey skin, Corii Sus domestica, Corii Bovis seu Bubali add Ganoderma, Lentinus Edodes, Hericium erinaceus (Bull. Ex Fr.) Pers., Chinese scholartree bolt bacterium, Poria, Polyporus, Coriolous Dersicolor (Fr.) Quel, Marasmius androsaceus (L.ex Fr.) Fr., armillaria mellea, Armillariella tabescens, Cordyceps, Cordyceps militaris (L.) Link., Tremella, Flammulina velutiper (Fr.) Sing, Auricularia, Grifola frondosa, Pleurotus ulmarius (Bullex Franch) Quel fungus, Schizophyllum commune Franch．, red edge are intended in shelf fungus, cephalosporium sinensis, peacilomyce hepiahi bacterium, Paecilomyces gunnii one or several.

When 11. production Colla Corii Asini, gelatinum oxhide, bubble skin, unhairing, cut skin, wash skin, skin of picking up, extract glue juice with add in Ganoderma, Lentinus Edodes, Hericium erinaceus (Bull. Ex Fr.) Pers., Chinese scholartree bolt bacterium, Poria, Polyporus, Coriolous Dersicolor (Fr.) Quel, Marasmius androsaceus (L.ex Fr.) Fr., armillaria mellea, Armillariella tabescens, Cordyceps, Cordyceps militaris (L.) Link., Tremella, Flammulina velutiper (Fr.) Sing, Auricularia, Grifola frondosa, Pleurotus ulmarius (Bullex Franch) Quel fungus, Schizophyllum commune Franch．, red edge plan shelf fungus, cephalosporium sinensis, peacilomyce hepiahi bacterium, Paecilomyces gunnii, Caulis Bambusae In Taeniam in water any one, or two kinds, or three kinds, or four kinds, or five kinds, or by that analogy to whole.

12. all with Corii Sus domestica, or when part Corii Sus domestica substitutes donkey skin production Colla Corii Asini, makes with the following method:

preparing the animal pig for doing Colla Corii Asini raw material, in the growth course of cattle live body, add and feed Ganoderma, Lentinus Edodes, Hericium erinaceus (Bull. Ex Fr.) Pers., Chinese scholartree bolt bacterium, Poria, Polyporus, Coriolous Dersicolor (Fr.) Quel, Marasmius androsaceus (L.ex Fr.) Fr., armillaria mellea, Armillariella tabescens, Cordyceps, Cordyceps militaris (L.) Link., Tremella, Flammulina velutiper (Fr.) Sing, Auricularia, Grifola frondosa, Pleurotus ulmarius (Bullex Franch) Quel fungus, Schizophyllum commune Franch．, red edge intends shelf fungus, cephalosporium sinensis, peacilomyce hepiahi bacterium, Paecilomyces gunnii, Caulis Bambusae In Taeniam, Fructus Crataegi, Massa Medicata Fermentata, Fructus Hordei Germinatus, Fructus Setariae Germinatus, Radix Ginseng, Radix Panacis Quinquefolii, Radix Codonopsis, the Radix Astragali, Rhizoma Dioscoreae, Radix Angelicae Sinensis, Radix Rehmanniae, Radix Polygoni Multiflori, Arillus Longan, Radix Morindae Officinalis, Herba Cistanches, Rhizoma Curculiginis, the Cortex Eucommiae, Radix Dipsaci, Rhizoma Cibotii, Rhizoma Drynariae, Fructus Psoraleae, Fructus Alpiniae Oxyphyllae, Semen Juglandis, Semen Cuscutae, Semen Astragali Complanati, Herba Cynomorii, fragrant-flowered garlic, Actinolitum, Radix Adenophorae (Radix Glehniae), Radix Ophiopogonis, Radix Asparagi, Herba Dendrobii, Rhizoma Polygonati Odorati, Rhizoma Polygonati, Bulbus Lilii, Fructus Lycii, Fructus Mori, Herba Ecliptae, Fructus Ligustri Lucidi, Semen Sesami Nigrum, Herba Leonuri, Fructus Litseae, Folium Artemisiae Argyi, Herba Limonii Gmelinii, Herb Gynostemmae Pentaphylli, add feed the kind of these materials can be wherein any one, also can be two kinds wherein, or three kinds, or four kinds, by that analogy to all, butcher rear bark fetching, partly or entirely substitute the raw materials for production of donkey skin as Colla Corii Asini, or

partly or entirely substitute with Corii Sus domestica, Corii Bovis seu Bubali donkey skin make the bubble skin of Colla Corii Asini, unhairing, cut skin, wash skin, skin of picking up, extract glue juice intend any one in shelf fungus, cephalosporium sinensis, peacilomyce hepiahi bacterium, Paecilomyces gunnii with in water containing Ganoderma, Lentinus Edodes, Hericium erinaceus (Bull. Ex Fr.) Pers., Chinese scholartree bolt bacterium, Poria, Polyporus, Coriolous Dersicolor (Fr.) Quel, Marasmius androsaceus (L.ex Fr.) Fr., armillaria mellea, Armillariella tabescens, Cordyceps, Cordyceps militaris (L.) Link., Tremella, Flammulina velutiper (Fr.) Sing, Auricularia, Grifola frondosa, Pleurotus ulmarius (Bullex Franch) Quel fungus, Schizophyllum commune Franch．, red edge, or two kinds, or three kinds, or four kinds, or five kinds, or by that analogy to whole.

13., when the concentrated glue juice operation that Colla Corii Asini is produced, carry out electric field treatment to glue juice, and the glue juice being about to concentrate is placed in electric field.

Such scheme can a kind ofly separately be applied, also can be comprehensively two or more, or all integrated applications.

Beneficial effect:

1. Ganoderma is to the function of the mankind, and according to existing scientific discovery, the effect of Ganoderma is very extensive.

Ganoderma chemical composition is mainly containing ergosterol 0.3% ~ 0.4%, fungal lysozyme and acid protease, L-mannitol, Xi alcohol.Containing water soluble protein in water-soluble extracting liquid, several amino acids, polypeptide and the polysaccharides such as aspartic acid, glutamic acid, arginine, lysine, leucine, alanine, tryptophan, threonine, proline, methionine, phenylalanine, serine.Still resinous, lactone, coumarin etc.Containing polysaccharide, ucleosides, furan derivative, steroid ferment class, alkaloids, protein, polypeptide, amino acids, triterpenes, sesquiterpene, organic germanium, inorganic salt etc. in the sporophore of Ganoderma, mycelium and spore.Ganoderan is one of principle active component of Ganoderma, has antitumor, immunomodulating, blood sugar lowering, antioxidation, blood fat reducing and anti-aging effects.Triterpenes contained by Ganoderma not lower over one hundred kind, wherein based on tetracyclic triterpenes, the bitterness of Ganoderma is relevant with contained triterpenes.Triterpenes is also one of effective ingredient of Ganoderma, has cytotoxicity to human liver cancer cell, also can suppress the release of histamine, has hepatoprotective effect and has anti-allergic effects etc.

antitumor action

Low or the imbalance of autoimmune function is why tumor can occur and the major reason expanded.Ganoderma is best Immunity regulation and activator, and it can significantly improve the immunologic function of body, strengthens the anti-cancer ability of patient self.Ganoderma can by promoting the generation of interleukin II, by promoting the phagocytic function of mononuclear phagocyte, by promoting the especially leukocytic index level of hematopoietic potential of human body, and to the inhibitory action of cancerous cell, become the preferred agents of antitumor, anti-cancer and assistant treating cancer by wherein some effective ingredient.Ganoderma to human body almost without any toxic and side effects.The advantage of this avirulent immune activation agent, many tumor chemotherapeutic drugs and other immunopotentiating agent do not have exactly.

protecting liver and detoxication effect

Ganoderma has protective effect to the hepatic injury that multiple physics and chemistry and biological factor cause.No matter before liver injury occurs or after generation, taking Ganoderma all can the liver protecting, alleviates hepatic injury.Ganoderma can promote that liver is to the metabolism of medicine, poisonous substance, has definite curative effect for toxic hepatitis.Especially chronic hepatitis, Ganoderma obviously can eliminate the symptoms such as dizziness, weak, nauseating, uncomfortable liver area, and effectively can improve liver function, makes indices be tending towards normal.So Ganoderma can be used for treating chronic poisoning, all kinds of chronic hepatitis, liver cirrhosis, hepatic insufficiency.

to the effect of cardiovascular system

Zoopery and clinical trial all show, Ganoderma can coronary artery dilator effectively, increases coronary flow; improve Myocardial Microcirculation, strengthen the supply of myocardium oxygen and energy, therefore; to myocardial ischemia, there is protective effect, treatment and the prevention of coronary heart diseases and angina pectoris etc. can be widely used in.To high fat of blood patient, Ganoderma can obviously reduce cholesterolemia, lipoprotein and triglyceride, and the formation of energy prevention of arterial atherosclerotic plaque.For atherosclerotic plaque former, then there are reduction Arterial Cholesterol content, vessel softening, prevent the effect of damage further.And can local microcirculation be improved, stop platelet aggregation.These effects have good preventive and therapeutic effect for polytype apoplexy.

anti-aging effects

Polysaccharide contained by Ganoderma, polypeptide etc. have obvious function of delaying senility.This effect is mainly based on following mechanism: promote and adjustment immunologic function.For adult and old people, this promotion and adjustment can obvious slow down aging.For the children being in growth and development stage, then can promote the perfect of its immunologic function, strengthen resistance against diseases, guarantee that it is grown up healthy and sound; Regulate metabolic balance, promote the synthesis of nucleic acid and protein.Research shows, the nucleic acid of serum, liver and bone marrow and the biosynthesis of protein when Ganoderma can be urged, therefore can be effectively disease-resistant anti-aging.Observation shows, takes Ganoderma with defying age, not only useful to old people, all applicable to the personage of business age level, because the process of growth promoter, namely moves towards old and feeble process; Anti-radical action.The interior originality defence antioxidant of radical damage that organism produces or the reduction of antioxidant enzyme material (as superoxide dismutase, SOD) are reasons of human senility.Ganoderan has significant plan SOD active, significantly can remove the free radical that body produces, thus stop the damage of radical pair body, prevent the peroxidating of fat body, protect cell, delayed cell ageing; Ganoderan can show chopsticks and promote cell nuclear dna synthesis capability, and can increase the division algebraically of cell, thus has delayed the aging of body.

neurasthenia effect

Ganoderma is just for neurasthenia and insomnia, therefore it plays good effect to maincenter.Extract energy exciting motion suppresses, mobility is reduced, coordination exercise is lacked of proper care, presents the sick effect in dose-dependent town, can curtail sleep to hexobarbital sleep effect, the time that central stimulants caffeine causes spasm and death can be extended, these results show, Ganoderma is inhibition effect to maincenter.The motherland contained Ganoderma of medicine can " be calmed the nerves ", " increasing wisdom ", " not forgetting ".It is reported, Ganoderma preparation has significant curative effect to neurasthenia's insomnia, and total effective rate is up to 87.14% ~ 100%.Within after general medication 10 ~ 15 days, namely occur obvious curative effects, be indicated as sleep improvement, appetite, body weight increase, and cardiopalmus, headache, dizziness alleviate or disappear, in high spirits, hypermnesia.Belong to QI and blood deficiency person's better efficacy.So Ganoderma has stronger regulating action for central nervous system, having effect of tranquillizing and allaying excitement, is indispensable good merchantable brand for the weak and insomniac of remarkable ability, and in state-promulgated pharmacopoeia, Ganoderma is exactly effective sleeping medicine of allaying excitement.

Organic germanium contained in Ganoderma is 3-5 times of Radix Ginseng, and modern medicine shows, the guarantor benefit effect of organic germanium to human body is very powerful.Can also utilize the beneficiation technologies of edible and medical fungi to inorganic Ge that inorganic Ge is converted into organic germanium.Germanium can increase the hemopoietic function of human body exactly to human body one important effect very, just only it is combined with Colla Corii Asini with this point, both hemoposieises just can be made to present summation action.

Ganoderma has been approved as by ministry of Health of China and has been food and drug substances, and this just proves that Ganoderma is without any toxic and side effects completely.The range of application of Ganoderma widely.See with regard to differential diagnosis in tcm, because this product enters the five internal organs kidney tonification whole body QI of five ZANG-organs, so no matter the heart, lung, liver,spleen,kidney deficiency of five ZANG-organs are weak, all can take it.Ganoderma is cured the disease to plant and relates to each systems such as breathing, circulation, digestion, nerve, endocrine and motion; Contain inside and outside, woman, youngster, face each section disease.Its basic reason, is just Ganoderma strengthening the body resistance, strengthens immunologic function, improves the great function of Abwehrkraft des Koepers.It is different from general medicine and plays therapeutical effect to certain disease; also be different from general nutritional health food only to carry out supplementing and strengthening to the deficiency of nutrient in a certain respect; but two-ways regulation function of human body balances on the whole; transfer internal body vigor; regulate human metabolism's function; improve autoimmune ability, impel whole internal organs or organ function normalization.

Further, Ganoderma is as the very influential traditional culture of China, very extensive at power of influence among the people, implants Ganoderma culture, not only can invest commodity high-performance technically, can also promote the added value of commodity, improve commodity value in commodity.

That now Ganoderma and Colla Corii Asini are produced is combined in one piece, does to analyze as follows:

Test shows the function of lucidum soaked juice: mainly kill bacteria, namely has broad-spectrum antibacterial action, especially has significant inhibitory action to Gram-negative and positive bacteria; But it is not remarkable to Mycophyta inhibitory action effect.This antiinflammatory action of Ganoderma, i.e. antibacterial action, especially Ganoderma mycelium extracting solution use cost is low, to the anticorrosion aspect that Colla Corii Asini is produced, especially in the bubble skin, extraction juice water of production Colla Corii Asini, Ganoderma is added, just can produce natural antisepsis to animal skins, substantially can not produce rotten odor.

So, in Colla Corii Asini production process, add Ganoderma except Colla Corii Asini can be made to strengthen except the function of above-mentioned Ganoderma, can also reduce the cost of Ganoderma deep processing.

2. Lentinus Edodes is to the function of the mankind, and according to existing scientific discovery, the effect of Lentinus Edodes is very extensive.

Lentinan can improve the vigor of complementary T cell and strengthen human body fluid immunologic function.Facts have proved in a large number, the anti-curing cancers of Lentinus Edodes in extensive range, for clinical treatment.Lentinus Edodes is also containing multivitamin, mineral, and to promotion human metabolism, improving organism adaptation power has great role.Lentinus Edodes also plays therapeutical effect to diabetes, pulmonary tuberculosis, infectious hepatitis, neuritis etc., can be used for again dyspepsia, constipation, fat-reducing etc.Lentinus Edodes " QI invigorating is not hungry, control wind removing blood stasis and stomach reinforcing helps food " is recorded in the many ancient books of China.Among the people being used for helps bringing out of variola, measles, controls headache, dizziness.Modern study proves, lentinan scalable people Xiu Nei has the T cell of immunologic function active, can reduce the ability of methyl cholanthrene induced tumor.Lentinus Edodes has strong inhibitory action to cancerous cell, is 97.5% to the suppression ratio of white mice sarcoma 180, is 80% to the suppression ratio of ehrlich carcinoma.Lentinus Edodes, also containing double stranded RNA, can be induced and produce interferon, have anti-virus ability.

Lentinus Edodes is as the food be very famous, and modern biology research shows, its mycelium cultivated can be utilized to be applied in Colla Corii Asini production, because shiitake mushroom hypha must not directly eat, but can suitability for industrialized production, cost is also ten low, but concrete medical value is identical with mushroom fruiting body.Lentinus Edodes composition is added in Colla Corii Asini, effectively can reduces the side effect that edible Colla Corii Asini does not hinder digestion, because Lentinus Edodes is aid digestion.And Lentinus Edodes is added on after in Colla Corii Asini, the antitumor action of Colla Corii Asini can be strengthened.

3. Hericium erinaceus (Bull. Ex Fr.) Pers. is to the function of the mankind, and according to existing scientific discovery, its effect is very extensive.

Hericium erinaceus (Bull. Ex Fr.) Pers. is containing unsaturated fatty acid, and can reduce cholesterolemia and content of triglyceride, adjusting blood lipid, be beneficial to blood circulation, be the ultimate food of cardiovascular patient; The polysaccharide body that Hericium erinaceus (Bull. Ex Fr.) Pers. contains, polypeptide class and fatty material, the synthesis of hereditary material in energy anticancer, thus prevention and therapy alimentary tract cancer and other malignant tumor; Containing several amino acids and abundant polysaccharide body in Hericium erinaceus (Bull. Ex Fr.) Pers., can be aid digestion, the curative effect of the digestive tract disease such as gastritis, gastric cancer, esophageal carcinoma, gastric ulcer, duodenal ulcer is attracted people's attention; Hericium erinaceus (Bull. Ex Fr.) Pers. has the function improving body immunity, delaying sanility.

Hericium erinaceus (Bull. Ex Fr.) Pers. has the digestive function extremely helping people, and Colla Corii Asini is grown greasy, easily causes dyspeptic symptom.The spleen and stomach provide the material basis of the acquired, if spleen and stomach function is obstructed, better medicine human body also cannot be enjoyed.Therefore, in Colla Corii Asini is produced, coordinate Hericium erinaceus (Bull. Ex Fr.) Pers., can promote digesting and assimilating of Colla Corii Asini like this, effect doubles naturally.Test and fruit is shown: the bad person of spleen and stomach function eats the Colla Corii Asini do not added containing Hericium erinaceus (Bull. Ex Fr.) Pers., usually shows dyspeptic result, but edible containing after the Colla Corii Asini of Hericium erinaceus (Bull. Ex Fr.) Pers., just do not have this phenomenon to occur.

4. Chinese scholartree bolt bacterium is to the function of the mankind, and according to existing scientific discovery, its effect is very extensive.

Modern study shows, Chinese scholartree bolt bacterium has tumor suppression clearly to act on life cycle with prolongation, can significantly improve body's immunity, and illustrate the composition, physicochemical property, molecular weight etc. of main active proteoglycan-PST.His the safety non-toxic side reaction of toxicological study and I clinical trial phase sufficient proof.II, III clinical trial phase confirms have cloudy inhibiting cancer to grow to advanced primary liver cancer patient, and the effect such as relief of symptoms, life-saving, evident in efficacy, total effective rate 75.96%, the annual rate of depositing reaches 44.7%, is better than 5-Fu, methyl Chinese blister beetle of class amine etc.

Chinese scholartree bolt bacterium is coordinated with Colla Corii Asini, the tumour inhibiting rate of Colla Corii Asini can be improved greatly.The basic reason of cancer is deficiency of the kidney yin.

5. Poria is to the function of the mankind, and according to existing scientific discovery, its effect is very extensive.

Poria energy enhancing human body immunity function, pachyman has obvious antitumor action; There is diuresis, the electrolytical discharge such as potassium, sodium, chlorine in urine can be increased; There is the effect such as generation, blood sugar lowering, anti-radiation of calmness and the liver protecting, suppression ulcer.Poria is also used as cake, Poria shortcake and tuckahoe wine etc.Some countries are using the raw material of Poria as naval's common drug and tonic.In the larger area of temperature and place, Poria can be used as important dietetic therapy kind, often ediblely can spleen invigorating dry, aid digestion, strong body constitution.

6. Polyporus is to the function of the mankind, and according to existing scientific discovery, its effect is very extensive.

Polyporus not only has diuresis and antibacterial action, finds that there is antitumaous effect after deliberation, and especially when adding Polyporus in the bubble skin water producing Colla Corii Asini, can have the generation of the putrefaction suppressing skin class, residual substance can strengthen the antitumaous effect of Colla Corii Asini.

7. Coriolous Dersicolor (Fr.) Quel is to the function of the mankind, and according to existing scientific discovery, its effect is very extensive.

Containing a kind of cancer-resisting substance in sporophore.This bacterium is medicinal, dries, reduces phlegm, treats lung disease.Treatment chronic bronchitis, unresolved chronic hepatitis etc. is effective in cure.Coriolous Dersicolor (Fr.) Quel can be used as the medicine of liver cancer immunity treatment.The polysaccharide that mycelium extracts and the polysaccharide that extracts from fermentation liquid all have strong press down carcinous.80% and 100% are respectively to the suppression ratio of white mice sarcoma 180 and ehrlich carcinoma.Its Synergistic action is determined to have many data to prove, also shows that oral polysaccharide reacts without long term toxicity.

8. Marasmius androsaceus (L.ex Fr.) Fr. is to the function of the mankind, according to existing scientific discovery, mainly contains good analgesic activity, also has good antioxidation, this antioxidation, the anti-aging effects very large to human body, long-term taking toxic effects.By Marasmius androsaceus (L.ex Fr.) Fr. and Colla Corii Asini with the use of, the curative effect of Colla Corii Asini treatment arthralgia can be improved because be that modern medicine confirms that the antiinflammatory action of Marasmius androsaceus (L.ex Fr.) Fr. has and has no side effect, curative effect feature certainly.With the analgesic effect of Marasmius androsaceus (L.ex Fr.) Fr., when Colla Corii Asini is developed as antitumor drug, be of great significance, longed for because pain relieving is each tumor patient, and chemical analgesic have its defect that can not evade.

9. armillaria mellea and Armillariella tabescens are to the function of the mankind, according to existing scientific discovery, suitable with the effect of Rhizoma Gastrodiae, also have antiinflammatory action, are engaged in one piece, can improve the town wind effect of Colla Corii Asini with Colla Corii Asini.In addition, armillaria mellea and Armillariella tabescens filament liquid have antiinflammatory action, have antisepsis to animal skins class when producing Colla Corii Asini.

10. Cordyceps and relevant modern culture thereof are to the function of the mankind, and according to existing scientific discovery, their effect is very extensive.

Use cordycepin mostly to be adjuvant therapy of malignant tumor clinically, symptom is improved more than 91.7%; Be mainly used in rhinocarcinoma, pharyngeal cancer, pulmonary carcinoma, leukemia, the patient of the brain cancer and other malignant tumor.In Cordyceps militaris (L.) Link., the content of cordycepic acid is 3.09 grams, and wild Cordyceps is 5.54 grams, and cordycepic acid is a kind of D--mannitol, and mannitol can improve plasma osmotic pressure, causes in in-house moisture intravasation, thus alleviates tissue edema, supplements blood plasma.Cordycepic acid is used for cerebral edema, and control acute renal failure, has the effect regulating the heart, brain, blood vessel, promotes the metabolism of human body, the microcirculation improving human body, blood fat reducing, blood pressure lowering.In Cordyceps militaris (L.) Link., the content of Cordyceps polysaccharide is 12.8 grams, and wild be 7.0 grams, the mechanism of action of Cordyceps polysaccharide in human body is: promote T lymphocyte, macrophage, leukocytic reproduction restraint, produce various Immunity active factor, promote the reproduction restraint of bone marrow stem cell, sexual cell, promote metabolism and the blood circulation of the heart, brain cell.The pharmacological testing of Cordyceps polysaccharide proves: Cordyceps polysaccharide has antitumor, anti-infection effect, sexual function improving, kidney invigorating and YANG supporting, beneficial vital essence, prevents aging, life lengthening; Significant effect is had to old people's chronic bronchitis, pulmonary heart disease.The detoxification ability of liver can be improved, play the effect holding up liver.Blood sugar lowering, blood fat reducing, the patient of anemia is used for enriching blood, and strengthens the nutrient flow amount of spleen, and Cordyceps polysaccharide, biological activity are strong, wide adaptability, also has anoxia enduring, analgesia, a calm effect.

Especially its hemopoietic function, can strengthen bone marrow and generate platelet, erythrocyte and leukocytic ability, share the synergism that can strengthen both with hematonic.

Add Cordyceps culture in Chinese tremendous influence power, combine with this famous traditional culture of Colla Corii Asini, can bring out the best in each other.

Recent year has adopted and has obtained Cordycepts sinensis with natural cs fungi fermentation method.Its property of medicine is gentle, throughout the year equal edible, and old or young, sick, weak, virtual person is all suitable, has medical value widely than the tonic of other kinds.

Because natural Cordyceps has become scarce commodity, price is rather stiff, existing artificial culture product, or the mycelium of the Cordyceps cultivated, show according to the study, and it is to effect of human body and natural suitable.

The succedaneum peacilomyce hepiahi bacterium of Cordyceps is Cordyceps separating obtained from fresh Cordyceps fungus (cordyceps sinensis (Berk) sacc)---peacilomyce hepiahi (Paecilomyces hepiali Chen & Dai) is cultivated through liquid submerged fermentation and is formed, its good clinical effectiveness and safety reliably obtain the accreditation of domestic and international medical experts and scholars deeply, the evaluation of committee of pharmacopeia of state of China is: come from Cordyceps, the same Cordyceps of merit! Because artificial bio-membrane's method can be adopted to produce, the finished product price of this product only Cordyceps about 10%, use this product in the present invention, because can directly utilize fermentation liquid to make an addition to during Colla Corii Asini produces, eliminate operations such as this product mycelia liquid concentrate, then cost is lower.

Cordyceps militaris (L.) Link. is as the succedaneum of Cordyceps, and existing ripe artificial breeding technique, manually can cultivate Cordyceps militaris (L.) Link.sporophore and mycelium, when using mycelium in the present invention, can effectively reduce costs.Cordyceps militaris (L.) Link. is suitable with Cordyceps to the function of human body.Caterpillar fungus cephalosporin powder, compared with natural cs, has several large feature: similar in chemical composition and pharmacological action; Caterpillar fungus cephalosporin powder and toxicity are lower than natural cs; Caterpillar fungus cephalosporin powder price well below natural cs, and can be produced in a large number.Caterpillar fungus cephalosporin powder shows through pharmacology and toxicological test: have certain sedation to central nervous system; Animal Anoxia ability can be strengthened; The monocytic phagocytic function of animal can be promoted; Subacute survey thing result: to the heart of animal, liver, spleen, the organs such as lung kidney are without impact, and histopathologic examination is without significant change; To animal without teratogenesis, mutagenic action; Extremely low to human body toxicity, with 14.3g/Kgw body weight letting animals feed, none is impaired, LD50=57.94 ± 1.94G/Kg; 74.5% is reached to Experimental Arrhythmia total effective rate; Significant curative effect is had to bradyarrhythmia and fast-slow syndrome of sick hole; Significant curative effect is had for chronic hepatitis or as its auxiliary treatment. test on immune function shows; The non-specific immunity tool of caterpillar fungus cephalosporin powder not only antagonist has certain effect, and can also significantly improve the specific immunity ability of body, is a kind of enhancing immune drug well.

Hepialidae Paecilomycerol powder (fermented Cordyceps powder) is Cordyceps separating obtained from fresh Cordyceps fungus---peacilomyce hepiahi is cultivated through liquid submerged fermentation and is formed, polysaccharide contained by it can start human macrophages, strengthening immunity and hematopoietic potential, just can produce good synergism with having the Colla Corii Asini of blood nourishing function with this point.The effect of Hepialidae Paecilomycerol powder to all kinds of crowd roughly has: for male, nose allergic symptom of can releiving. invigorating kidney-YANG, lung moistening. and improving water flood quality, psychentonia of releiving. supplement energy, indefatigability; For women, can nourishing qi and blood, solve menses worry, brothers are ice-cold. to defying age, make skin children tender, white touched with red. slow down aging, build up resistance. improve body constitution, stress of releiving, be combined in one piece with this function of Hepialidae Paecilomycerol powder and Colla Corii Asini to use, good synergism can be produced; For old people: can enriching yin and nourishing kidney void. strengthening cardio-pulmonary function, supplement energy. promote spleen function, bone and muscle strengthening. strengthen blood flow, vision enhancing; For infant: can build up resistance, respiratory problems of releiving. the symptoms such as minimizing is caught a cold, cough, nose is responsive. antagonism brain is tired, and take good care of spirit, antiallergic is former. promote memory, nourishing the brain and improving intelligence.Paecilomyces gunnii is also cultivate through liquid submerged fermentation to form, similar to aforementioned to the function of human body, and especially its effect of scavenging free radicals of having is comparatively obvious especially.

11. Tremella, to the function of the mankind, according to existing scientific discovery, act on very extensive.

Tremella has strong essence, the kidney invigorating, intestine moistening, stomach reinforcing, QI invigorating and blood, heart tonifying, strong body, supplementing the brain, refreshes oneself, improves looks, effect of skin care, life lengthening.For controlling the diseases such as cough due to lung-heat, dryness of the lung dry cough, menoxenia, gastritis, constipation.It can improve liver detoxification ability, the liver protecting function, and it not only can enhancing body antineoplastic immunocompetence, can also strengthen the tolerance of tumor patient to radiotherapy, chemotherapy.It is also tonic medicine simply, and feature is moist and oiliness stagnant, has spleen reinforcing appetizing, QI invigorating bowel relieving, sleeping stomach invigorating, supplementing the brain, replenishing YIN and removing heat, the merit of moisturizing, and is not a kind of good tonic to hyperactivity of fire caused by deficiency of YIN by the patient of ginseng and pilose antler Isothermal Hot nourishing.Tremella is rich in natural characteristic colloid, adds its nourishing yin effect, and long-term taking can skin moistening, and has the effect dispelling face's chloasma, freckle.Tremella is and the diet food of planting containing dietary fiber, and its dietary fiber can help gastrointestinal peristalsis, reduces fat absorption.These functions of Tremella, are combined with Colla Corii Asini, can produce: Tremella is useful to taste, and effectively can reduce the unfavorable digestion of taking Colla Corii Asini has unfavorable aspect; Tremella to menoxenia, the YIN nourishing of women, dispel face's chloasma and freckle is effective, good medicine is combined with this gynecological of Colla Corii Asini, can produce good mating reaction; Tremella to the tolerance of chemotherapy to improvement tumor patient, is combined with the anticancer function of Colla Corii Asini, can produces synergism.

12. Caulis Bambusae In Taeniam, to the function of the mankind, according to existing scientific discovery, act on very extensive.

Contain crude protein 19.4%, crude fat 2.6% in dry Dictyophora Indusiata according to surveying and determination, soluble N-free topples over thing total amount 60.4%, wherein bacterium sugar 4.2%, crude fibre 8.4%, ash 9.3%.It has remarkable result, energy cancer-resisting, the strong body of fat-reducing to treatment hypertension, neurasthenia, gastroenteropathy etc.Also there is special anti-corrosion function, add the dish of the Caulis Bambusae In Taeniam cooking summer, meat many days is constant turns sour.Caulis Bambusae In Taeniam or its mycelium is used in Colla Corii Asini production process, according to surveying and determination, there is obvious inhibitory action to Gram-negative and positive bacteria, penicillium sp, Aspergillus flavus, aspergillus niger, the generation of the stink in production process can be suppressed significantly, and the generation of the abnormal stink of finished product colloid.The composition of Caulis Bambusae In Taeniam is applied to after in Colla Corii Asini production process; except can suppressing the generation of colloid stink, the medical function of Colla Corii Asini can also be strengthened, such as; because Caulis Bambusae In Taeniam can the liver protecting; reduce the accumulation of Abdominal Wall Fat, thus produce the effect of blood pressure lowering, blood fat reducing and fat-reducing, Colla Corii Asini is gynecological's panacea; fat-reducing is also the thing that women dreams of; both combinations, just both can lose weight, can mend health again.

13. Grifola frondosa, to the function of the mankind, according to existing scientific discovery, act on very extensive.

Grifola frondosa (cry again dance fine and soft, formal name used at school: Grifola frondosa, English name: Maitake) is a kind of medicine-food two-purpose mushrooms, and the good mouthfeel of taste is good and have legend drug effect.The most effective active composition extracted from dance young pilose antler is waved fine and soft D-fraction and is had extremely strong anticancer function.Be combined into the glucosan of side chain containing being combined into main chain β-(1-3) with β-(1-6) and being combined into β-(1-3) the active glucosan that main chain β-(1-6) is combined into side chain in dance young pilose antler, experiment proves the growth of these active glucosans remarkable Tumor suppression by activated immune function; Also find that the active glucosan of purification only has by injection ability effective simultaneously, and wave the conjugate of the active glucosan of fine and soft D-fraction(and albumen) just can obtain desirable effect by oral.Grifola frondosa to human body without any malicious toxic and side effects.

Grifolan water soluble, after Grifola frondosa is combined with Colla Corii Asini, zoopery and the fine and soft D-fraction of clinical experiment display dance play anti-cancer and kill cancer action by the following aspects: the immunocytes such as activating phagocytic cells, natural killer cell, nocuity T cell, induction leukin, interferon-γ, the secretion of the cytokines such as tumor necrosis factor-alpha; Cancer cell specific induction of apoptosis; Share with traditional chemotherapeutic agent (mitomycin, Ka Mosiding etc.), both increased drug effect, and alleviated again the toxic and side effects in chemotherapy process; Synergism is had with immunotherapy medicaments (interferon-' alpha ' 2b); Slow down the pain of patient with advanced cancer, increase appetite, improve the quality of life of patient.

14. Pleurotus ulmarius (Bullex Franch) Quel fungus, to the function of the mankind, according to existing scientific discovery, act on very extensive.

Pleurotus ulmarius (Bullex Franch) Quel fungus formal name used at school Gleoesterum incarnatum, also claims Pleurotus citrinopileatus Sing (Pleurotus ulmarius (Bull. Ex Fr.) Quel.), has functions such as strengthening immunity, antiinflammatory, antiulcer.The bubble severe edema due to hypofunction of the spleen containing Pleurotus ulmarius (Bullex Franch) Quel fungus composition, the water extracting glue juice is used in Colla Corii Asini production procedure of the present invention, because the bacteriostatic activity of Pleurotus ulmarius（ Bullex Franch） Quel is strong, antimicrobial spectrum is wide, thus have very good antisepsis, the generation of skin poison taste can be suppressed aborning significantly, can ensure that the abnormal flavour composition of finished product Colla Corii Asini is reduced to minimum.

15. Schizophyllum commune Franch．s are to the function of the mankind, and Schizophyllum commune Franch． is Radix Ginseng again, and according to existing scientific discovery, their effect mainly contains: because containing Schizophyllum commune Fr polysaccharides, so have inhibitory action to animal tumor, be 70% to the suppression ratio of white mice sarcoma 180 and ehrlich carcinoma.Be 70-100% to the suppression ratio of rat Jitian tumor and white mice sarcoma 37.Schizophyllum commune Franch． is mainly used in deficiency of kidney-QI, impotence and premature ejaculation, Hypomenorrhea.After Schizophyllum commune Franch． and Colla Corii Asini group 5, when being applied to gynaecopathia with the method for dietetic therapy, there is good therapeutical effect to the leukorrhagia of women.

16. red edge intend shelf fungus to the function of the mankind, according to existing scientific discovery, have inhibitory action to tumor.

17. Auricularias, comprise Auricularia and Tremella, and Tremella is exactly Tremella in fact, and they are to the function of the mankind, and according to existing scientific discovery, Auricularia contains anti-tumor active substance, energy enhancing human body immunity power; Colloid in Auricularia plays to human body the effect that clearing stomach washs intestinal and helps digest, and when it being coordinated with Colla Corii Asini, can effectively eliminate the drawback taking the unfavorable digestion of Colla Corii Asini; Because of the usefulness of enriching blood that Auricularia is good, be engaged in one piece with Colla Corii Asini, both can produce good synergism.

18. Phellinus igniarius (L. ex Fr.) Quel. are called for short again Phellinus igniarius (L. ex Fr.) Quel. bacterium, and it belongs to Polyporaceae, wood layer hole strain fungus, and modern study confirms, Phellinus igniarius (L. ex Fr.) Quel. and Colla Corii Asini compatibility can be improved the immunity of human body, alleviate the side effect of anticarcinogen, so can be used to the radiation and chemotherapy of adjuvant therapy patient.Especially, fairly obvious to the curative effect of the gynaecopathias such as female irregular menstruation after Phellinus igniarius (L. ex Fr.) Quel. being coordinated with Colla Corii Asini.Relevant research shows, Phellinus igniarius (L. ex Fr.) Quel. and extract harmless to human non-toxic, even if long-term, high-dose is taken also without any side effects.

The composition of litsea cubeba oil or Fructus Litseae to add and is that can produce these during Colla Corii Asini is produced acts on by 19.: have good flavouring and antisepsis to finished product Colla Corii Asini, after adding Fructus Litseae aborning, effectively can remove some bad flavor in Colla Corii Asini, increase the natural fragrance of one cousin.

20. add with compositions such as grass Fructus Setariae Germinatus, Fructus Hordei Germinatus (containing Semen Fagopyri Esculenti), Fructus Setariae Germinatus in the production process of Colla Corii Asini, have following benefit: because Fructus Setariae Germinatus, Fructus Hordei Germinatus, the peptic effect of Fructus Setariae Germinatus class, can for the disadvantage alleviating Colla Corii Asini and hinder digestion; Because containing a large amount of enzyme in Fructus Setariae Germinatus, Fructus Hordei Germinatus, Fructus Setariae Germinatus, for the animal skins facilitating process for producing glue, and the corruption alleviating animal skins has certain effect, when especially ferment treatment being carried out to the primary raw material animal skins of producing Colla Corii Asini, enzyme dosage 10%-30% can be reduced.

Find Radix Et Rhizoma Fagopyri Tatarici stem and leaf to coordinate with Colla Corii Asini can strengthen Colla Corii Asini physical strength profiting, continue spirit, sharp knowledge, sending down the abnormal ascending QI, wide intestinal, stomach invigorating, control choke eat, carbuncle, hemostasis lose the functions such as nauseating.

21. by the raw material of the animals' reproduction organ parts such as Ren caprae seu ovis Testis Et penis Caprae seu Ovis, Testis et Pentis Canis Penis et testis canitis, Ren Tigris Penis et testis Tigris, leopard kidney leopard whip, Testis Et penis Equi Testis Et penis Equi, Testis et penis Gallus domesticus, Ren Bovis seu Bubali Testis Et penis Bovis seu Bubali, Penis et testis sus domestica, Testis et penis callorhini as Colla Corii Asini, a feature to improve the sexual function level of finished product Colla Corii Asini to the mankind, just can develop separately the donkey-hide gelatin product being exclusively used in male whereby, coordinate the Cordyceps in aforesaid medicine edible fungi, Ganoderma class material again, more can improve the effect of Colla Corii Asini enriching yin and nourishing kidney.If, add in the live body growth course of the animals such as these Ren caprae seu ovis Testis Et penis Caprae seu Ovis, Testis et Pentis Canis Penis et testis canitis, Testis Et penis Equi Testis Et penis Equi, Testis et penis Gallus domesticus, Ren Bovis seu Bubali Testis Et penis Bovis seu Bubali, Penis et testis sus domestica and feed medicine edible fungi of the present invention, recycle the raw material one of of the genitals of these animals as Colla Corii Asini after tonify deficiency Chinese herbal medicine, the kidney invigorating and YANG supporting effect of finished product Colla Corii Asini can be improved especially.Concrete effect shows as: after share with Colla Corii Asini, can significantly strengthen control sexual impotence, soreness of bones and muscles, bone tuberculosis, osteomyelitis, asthenia of qi and blood lose, the function of the disease aspect such as women's hypogalactia.

22. pairs produce Colla Corii Asini industrial water, carry out magnetization treatment with vapour after, beneficial effect is: the water quality used of the original producton location due to Donga Colla Corii Asini is inherently because rich in mineral substances, the water of proportion just than common is large, after magnetization, more can activate effective mineral composition that water is, more can improve the drug effect function of Colla Corii Asini; Compendium of Material Medica thinks that magnetic water has " removing skin ulcer fistula, longue skin ", " Long Drinks has made us son, tonifying YANG " effect such as " should enter wine ", after being magnetized by the water producing Colla Corii Asini, as with the addition of the composition useful to human body in donkey-hide gelatin product; Because the water after magnetization has bacteriostasis, the corrupt speed of Colla Corii Asini raw material can be reduced, reduce stink; Use magnetic water to produce to Colla Corii Asini the cost increased very low, because if use permanent magnetism process water source, substantially do not consume the energy.

23. Colla Corii Asini and other colloid, normal product is in water after ebuillition of heated, and low baking temperature number minute, namely solubilized, can not dissolve if exceed the regular hour, be exactly defective Colla Corii Asini.Producing one of reason of defective Colla Corii Asini is: change hypertonia during skin, the time is too short, causes proteolysis incomplete.The modern production technique of the appearance of this situation normally Colla Corii Asini causes.Do thermal source in the present invention at employing quicklime to extract glue juice or concentrated glue juice and have these effectively to locate: be that requirement slow fire heats when will take glue juice in the traditional processing technology of Colla Corii Asini, keep micro-to boil 1 ~ 2 day, after doing thermal source with quicklime, just in time can meet this condition; Because the heating of quicklime thermal source is stable, balanced, can ensure that glue juice can not be charred; Because produce Colla Corii Asini without firepower, the probability of new product Colla Corii Asini possibility " getting angry " can be reduced; Utilize quicklime slaking to become the heating power produced during Calx to produce Colla Corii Asini and substantially can consume the energy; Can by the Colla Corii Asini produced with quicklime as a kind of high-end product; At the container exterior parcel insulation material of splendid attire quicklime, after heat-insulation and heat-preservation, just the thermal efficiency can be improved; When the container containing rubber or glue juice is made pressurisable container, the thermal efficiency can be improved especially.

24. add hello Ganoderma to the animal material live body preparing Colla Corii Asini raw material, the medicine edible fungi composition that Cordyceps etc. are famous, or/and Radix Ginseng, Radix Panacis Quinquefolii, Radix Codonopsis, the Radix Astragali, Rhizoma Dioscoreae, Radix Angelicae Sinensis, Radix Rehmanniae, Radix Polygoni Multiflori, Arillus Longan, Radix Morindae Officinalis, Herba Cistanches, Rhizoma Curculiginis, the Cortex Eucommiae, Radix Dipsaci, Rhizoma Cibotii, Rhizoma Drynariae, Fructus Psoraleae, Fructus Alpiniae Oxyphyllae, Semen Juglandis, Semen Cuscutae, Semen Astragali Complanati, Herba Cynomorii, fragrant-flowered garlic, Actinolitum, Radix Adenophorae (Radix Glehniae), Radix Ophiopogonis, Radix Asparagi, Herba Dendrobii, Rhizoma Polygonati Odorati, Rhizoma Polygonati, Bulbus Lilii, Fructus Lycii, Herb Gynostemmae Pentaphylli, Fructus Mori, Herba Ecliptae, after the qi-restoratives medicines such as Fructus Ligustri Lucidi and other Chinese herbal medicine, there is following benefit: these compositions itself can improve the production efficiency of animal itself, more do not add the speed of growth more than 10% that can improve animal of feeding, strengthen animal body constitution thus the morbidity risk rate of reduction animal, because add feed these materials have passed through this natural biological respinse process of animal after, some in these materials may bring dysgenic material by after animal process to human body, through animal metabolism principle and drug metabolism principle, some harmful material is drained, and the composition useful to human body will be accumulated and become natural health care and medical composition in animal body, the medical value of Carnis Equi Asini donkey skin can be improved, especially the kidney invigorating and Yang strengthening function of Testis Et penis Equi Testis Et penis Equi can be improved, after improving the health value of Carnis Equi Asini, just can improve Carnis Equi Asini the market influence and improve meat donkey deliver speed for sale after, the enthusiasm for production of donkey class culturist can be improved, the anxiety alleviating Colla Corii Asini raw material donkey skin is of great benefit to, also find a function, exactly meat donkey is added and feed Caulis Bambusae In Taeniam, after the compositions such as Pleurotus ulmarius（ Bullex Franch） Quel, the rancid degree of donkey skin when making Colla Corii Asini can be reduced, produce raw material by this way and can make very high-end Colla Corii Asini product, the Testis Et penis Equi Testis Et penis Equi formed by this programme is made after Colla Corii Asini as one of raw material, and the function of its strengthening yang and invigorating kidney is enhanced, and as one Colla Corii Asini exploitation for men only, can make up the market vacancy, it is higher that the sporophore of direct use edible and medical fungi adds the production cost of feeding animal, can this method edible and medical fungi mycelium that biological engineering method can be utilized to make, or fermentation liquid adds and feeds animal, and its cost is very cheap, and effect is as good as with using sporophore.

25. Herba Limonii Gmelinii cry again salt cloud grass, Limonium spp., Radix limonii sinensis, rock pine etc. title, function with cure mainly: clearing heat and expelling damp, hemostasis dissipating blood stasis, antiinflammatory.Control dysfunctional uterine hemorrhage, hematuria, bleeding hemorrhoids, proctoptosis, carbuncle, endometritis, cervical erosion etc., added and fed donkey, then using donkey skin after the raw material of Colla Corii Asini, because of in this donkey skin containing a small amount of Herba Limonii Gmelinii composition, thus also can function containing Herba Limonii Gmelinii in Colla Corii Asini, two combine, and can improve the curative effect of Colla Corii Asini in gynecological medical.

25. Herba Leonuris another name motherwort, Herba Leonuri, function mainly: promoting blood flow to regulate menstruation, inducing diuresis to remove edema.For menoxenia, dysmenorrhea, amenorrhea, lochiorrhea, edema oliguria; Acute nephritis edema is gynecological's good medicine famous simply.This method is not directly added in Colla Corii Asini by Herba Leonuri composition, because but by Herba Leonuri grassland grass Direct-fed donkey, the autotelic composition allowing donkey body include Herba Leonuri, then Colla Corii Asini is made with its skin or other organ, after so processing, the original of Herba Leonuri to the disadvantageous composition of human body, after donkey process of making a living, may disappear.The donkey series products of Herba Leonuri of feeding especially is suitable for women and eats.Herba Leonuri is easy to plantation, and output is very high, and the cost for foster donkey is very cheap.

26. Folium Artemisiae Argyis have the effect of regulating menstruation Zhi Xue ﹑ antiabortive Zhi Beng ﹑ dispelling cold and removing dampness.Control menstruation and do not adjust ﹑ dysmenorrhoea abdomen pain ﹑ miscarriage ﹑ metrorrhagia, radical cure of rheumatic closes the effects such as the scorching ﹑ head wind ﹑ month endogenous wind of joint, and these effects that Folium Artemisiae Argyi has just in time can produce good synergism with Colla Corii Asini.

Colla Corii Asini has been segmented market by 27. first technically, as: according to principle of the present invention, the Colla Corii Asini eaten for male reuses Cordyceps and succedaneum, Radix Morindae Officinalis, Herba Cistanches, Rhizoma Curculiginis, the Cortex Eucommiae, Radix Dipsaci, Rhizoma Cibotii, Rhizoma Drynariae, Fructus Psoraleae, Fructus Alpiniae Oxyphyllae, Semen Juglandis, Semen Cuscutae, Semen Astragali Complanati, Herba Cynomorii, fragrant-flowered garlic, the Actinolitum etc. of strengthening yang and invigorating kidney effect; The emphasis eaten for women coordinates tool to enrich blood, pacifies the Herba Leonuri, Folium Artemisiae Argyi, Schizophyllum commune Franch．, Auricularia, Herba Limonii Gmelinii, Radix Angelicae Sinensis, the Radix Astragali etc. of (tune) warp, YIN nourishing effect; Emphasis for old people market coordinate have calm the nerves, the Hericium erinaceus (Bull. Ex Fr.) Pers., armillaria mellea, Radix Adenophorae (Radix Glehniae) etc. of YIN nourishing, aid digestion effect.

28. adopt the present invention, substitute the Colla Corii Asini curative effect after donkey skin and economy has with Corii Sus domestica: the effective percentage for treatment anemia is minimum in test improves 5%, and soprano can improve 20%; Because have employed the Corii Sus domestica can supplied in a large number in market, the price of Corii Sus domestica is only three point 1/1st to five of donkey skin price, and the donkey skin cost in Colla Corii Asini production accounts for whole production cost about more than 90%, as can be seen here, substitute donkey skin production Colla Corii Asini with Corii Sus domestica and ensureing that its medical treatment can significantly reduce with cost on the basis of food therapy value; Even if implant the technology of the present invention on conventional art or modern ordinary skill, on the basis can improving the medical and edibility of Colla Corii Asini, can further segment market, with raising value-added content of product, for the high-end product developing Colla Corii Asini is laid a good foundation.Indices all meets Chinese Pharmacopoeia requirement.

29. Colla Corii Asini produce in add the edible fungi composition that is used as medicine after; be applied at Colla Corii Asini in the exploitation for the treatment of tumor and demonstrate: tumour inhibiting rate improves; and the survival of patients phase can be extended; Colla Corii Asini of the present invention (using Ganoderma, Grifola frondosa, Marasmius androsaceus (L.ex Fr.) Fr., Phellinus igniarius (L. ex Fr.) Quel. by the inventive method) is adopted directly to carry out tumor suppression and prolongation experiment life cycle in Mice Body; test the result display drawn for 4 times; its tumour inhibiting rate is respectively 65.31%, 58.09% and 39. 5%, researches and develops the tumor-inhibiting action index of " tumour inhibiting rate is not less than 3 0% " in project verification considerably beyond national PTS.And in prolongation experiment life cycle, research finds, obviously can extend the life cycle of mice with tumor, mouse storaging current extends 119.99%; Mice with tumor is agile, gloss, shows that medicine can improve life quality really; There is ideal analgesic effect.

Colla Corii Asini is that one solely originates in China, the precious Chinese patent medicine of world-famous.Along with the expansion of Colla Corii Asini production capacity, bringing new problem--Colla Corii Asini is produced and is faced the awkward situation that there is lack of raw materials.Donkey skin is the primary raw material of processing Colla Corii Asini, accounts for more than 98% of its material rate.According to statistics, domestic donkey skin resource declines with the speed of 20% every year in recent years.At present, donkey skin shortage of resources has become the large bottleneck that restriction Colla Corii Asini industry is accelerated development.According to investigation, China's donkey resource is sharply declining, and donkey is slaughtered family and reduces year by year, the competition of donkey skin, causes from a large amount of donkey skin of external import, also result in the significantly lifting of Chinese medicine Colla Corii Asini price, is unfavorable for very much the research and development of Colla Corii Asini.Therefore, be necessary to seek a kind of resource that can substitute donkey skin to reduce the production cost of Colla Corii Asini, or improve donkey skin usefulness/or improve donkey output, and synchronously Colla Corii Asini is carried out to the method for profound development and utilization.

The present invention just in time can lack the high donkey skin of price by the Corii Sus domestica Corii Bovis seu Bubali alternate resources that output is cheap greatly; Utilize this Project Technical to produce donkey skin make Colla Corii Asini after, application and the drug effect of Colla Corii Asini can be expanded further, simultaneously can improve Colla Corii Asini added value of product; The speed of growth of donkey can be improved, thus the quantity delivered of donkey skin can be improved; If continue to continue to use traditional technology to produce Colla Corii Asini, after utilizing invention, the drug effect of Colla Corii Asini can be improved and improve the production technology of Colla Corii Asini.

The cardinal principle of Project Technical of the present invention is to utilize pharmacokinetic principles to form in conjunction with the comprehensive modern nutriology principle of modern biological project principle, the great achievement of collection biologic pharmacological science.

30. product beta test situation

Setting technique scheme:

Technical scheme A: add hello donkey with Ganoderma and Lentinus edodes fermented product according to the ratio of the donkey body weight 1-5% that lives, then get its skin, technology makes Colla Corii Asini routinely.

Technical scheme B: to add in pig feed ratio 1-10% with Ganoderma and Lentinus edodes fermented product and feed pigs, then get its skin, technology makes Colla Corii Asini routinely.

Technical scheme C: make Colla Corii Asini with common donkey skin, but Ganoderma, Tremella, Hericium erinaceus (Bull. Ex Fr.) Pers. composition is added in the ratio of the 1-5% of donkey skin weight in manufacturing process, other is fabrication techniques routinely.

Test method A: add hello donkey with Ganoderma and Lentinus edodes fermented product according to the ratio of the donkey body weight 1-5% that lives, then get its skin, prepare the raw material being used as to make Colla Corii Asini.

Test method B: to add in pig feed ratio 1-10% with Ganoderma and Lentinus edodes fermented product and feed pigs, then get its skin, prepare the raw material being used as to make Colla Corii Asini

Test method C: make Colla Corii Asini by technical scheme C.

make Colla Corii Asini with common donkey skin, but add Ganoderma, Tremella, Hericium erinaceus (Bull. Ex Fr.) Pers. composition in the ratio of the 1-5% of donkey skin weight in manufacturing process, other is fabrication techniques routinely.

colla Corii Asini is made into the donkey skin of technical scheme A and B gained, Corii Sus domestica.

Carry out Amino Acid Composition analysis

Table 1 test gained Colla Corii Asini by analysis after with the contrast contrasting Colla Corii Asini

Hematopathy clinical observation on the therapeutic effect statistical table (%) treated by table 2

Table 3 is treated hematopathy symptom and is improved clinical observation on the therapeutic effect statistics (%) :

Table 4 adopts the price analysis contrast of this Project Technical as following table:

This Project Technical can large-scale production, and have good product cost, especially, after using this Project Technical to use Corii Sus domestica to substitute donkey skin production Colla Corii Asini, still can ensure that produced Colla Corii Asini curative effect is low unlike the Colla Corii Asini produced with donkey skin, cost can reduce by more than 50%.

In sum, the present invention is that the sustainable development of Chinese medicine colloid brings obvious beneficial effect, is especially the secondary development of Colla Corii Asini, with raw material substitution aspect, haves laid a good foundation technically.Other beneficial effect can see described content under each embodiment item.

Detailed description of the invention

Embodiment 1

Ganoderma is added in extraction glue juice water in production Colla Corii Asini flow process, Lentinus Edodes, Hericium erinaceus (Bull. Ex Fr.) Pers., Chinese scholartree bolt bacterium, Poria, Polyporus, Coriolous Dersicolor (Fr.) Quel, Marasmius androsaceus (L.ex Fr.) Fr., armillaria mellea, Armillariella tabescens, Cordyceps, Cordyceps militaris (L.) Link., Tremella, Flammulina velutiper (Fr.) Sing, Auricularia, Grifola frondosa, Pleurotus ulmarius (Bullex Franch) Quel fungus, Schizophyllum commune Franch．, red edge intends shelf fungus, cephalosporium sinensis, peacilomyce hepiahi bacterium, Paecilomyces gunnii, Fructus Litseae, Caulis Bambusae In Taeniam, Phellinus igniarius (L. ex Fr.) Quel., any one composition in Auricularia, or any two kinds of compositions, or any three kinds of compositions, or any four kinds of compositions, or any five kinds of compositions, or any six kinds of compositions, or any seven kinds of compositions, or any eight kinds of compositions, or any nine kinds of compositions, or any ten kinds of compositions, or any 11 kinds of compositions, or any 12 kinds of compositions, or any 13 kinds of compositions, or any 14 kinds of compositions, or any 15 kinds of compositions, or any 16 kinds of compositions, or any 17 kinds of compositions, or any 18 kinds of compositions, or any 19 kinds of compositions, or any 20 kinds of compositions, or any 21 kinds of compositions, or any 22 kinds of compositions, or whole composition.The interpolation quantity of these materials, if alone, often kind of material (comprise its sporophore or mycelium, water content is within 14%) adds 10-20 kilogram by 100 kilograms of Colla Corii Asini raw material animal skins; If several share, then add overall control at 15-30 kilogram by 100 kilograms of Colla Corii Asini raw material animal skins.

Add the compositions such as Ganoderma, Fructus Litseae, Caulis Bambusae In Taeniam, Pleurotus ulmarius (Bullex Franch) Quel fungus in bubble skin flow process, in order to reduce costs, can use their fermentation culture medium mycelium or its fermentation liquid, use amount can not be limit.

Below all suggestion uses fermentation culture medium.

Embodiment 2

Feeding medicinal fungus is added, or/and some Chinese herbal medicine in feeding to providing the live body of the animal pig of Colla Corii Asini raw material or donkey or cattle:

Method : add and feed Ganoderma, Lentinus Edodes, Hericium erinaceus (Bull. Ex Fr.) Pers., Chinese scholartree bolt bacterium, Poria, Polyporus, Coriolous Dersicolor (Fr.) Quel, Marasmius androsaceus (L.ex Fr.) Fr., armillaria mellea, Armillariella tabescens, Cordyceps, Cordyceps militaris (L.) Link., Tremella, Flammulina velutiper (Fr.) Sing, Auricularia, Grifola frondosa, Pleurotus ulmarius (Bullex Franch) Quel fungus, Schizophyllum commune Franch．, red edge intends shelf fungus, cephalosporium sinensis, peacilomyce hepiahi bacterium, Paecilomyces gunnii, Omphalia, Caulis Bambusae In Taeniam, Phellinus igniarius (L. ex Fr.) Quel., any one composition in Auricularia, or any two kinds of compositions, or any three kinds of compositions, or any four kinds of compositions, or any five kinds of compositions, or any six kinds of compositions, or any seven kinds of compositions, or any eight kinds of compositions, or any nine kinds of compositions, or any ten kinds of compositions, or any 11 kinds of compositions, or any 12 kinds of compositions, or any 13 kinds of compositions, or any 14 kinds of compositions, or any 15 kinds of compositions, or any 16 kinds of compositions, or any 17 kinds of compositions, or any 18 kinds of compositions, or any 19 kinds of compositions, or any 20 kinds of compositions, or any 21 kinds of compositions, or any 22 kinds of compositions, or aforementioned whole composition.

Method : add and feed Fructus Crataegi, Massa Medicata Fermentata, Fructus Hordei Germinatus, Fructus Setariae Germinatus, Radix Ginseng, Radix Panacis Quinquefolii, Radix Codonopsis, the Radix Astragali, Rhizoma Dioscoreae, Radix Angelicae Sinensis, Radix Rehmanniae, Radix Polygoni Multiflori, Arillus Longan, Radix Morindae Officinalis, Herba Cistanches, Rhizoma Curculiginis, the Cortex Eucommiae, Radix Dipsaci, Rhizoma Cibotii, Rhizoma Drynariae, Fructus Psoraleae, Fructus Alpiniae Oxyphyllae, Semen Juglandis, Semen Cuscutae, Semen Astragali Complanati, Herba Cynomorii, fragrant-flowered garlic, Actinolitum, Radix Adenophorae (Radix Glehniae), Radix Ophiopogonis, Radix Asparagi, Herba Dendrobii, Rhizoma Polygonati Odorati, Rhizoma Polygonati, Bulbus Lilii, Fructus Lycii, Fructus Mori, Herba Ecliptae, Fructus Ligustri Lucidi, Semen Sesami Nigrum, Herba Leonuri, Fructus Litseae, Folium Artemisiae Argyi, Herba Limonii Gmelinii, any one composition in Herb Gynostemmae Pentaphylli, or any two kinds of compositions, or any three kinds of compositions, or any four kinds of compositions, or any five kinds of compositions, or any six kinds of compositions, or any seven kinds of compositions, or any eight kinds of compositions, or any nine kinds of compositions, or any ten kinds of compositions, or any 11 kinds of compositions, or any 12 kinds of compositions, or any 13 kinds of compositions, or any 14 kinds of compositions, or any 15 kinds of compositions, or any 16 kinds of compositions, or any 17 kinds of compositions, or any 18 kinds of compositions, or any 19 kinds of compositions, or any 20 kinds of compositions, or any 21 kinds of compositions, or any 22 kinds of compositions, or any 23 kinds of compositions, or any 24 kinds of compositions, or any 25 kinds of compositions, or any 26 kinds of compositions, or any 27 kinds of compositions, or any 28 kinds of compositions, or any 29 kinds of compositions, or any 30 kinds of compositions, or any 31 kinds of compositions, or any 32 kinds of compositions, or any 33 kinds of compositions, or any 34 kinds of compositions, or any 35 kinds of compositions, or any 36 kinds of compositions, or any 37 kinds of compositions, or any 38 kinds of compositions, or any 39 kinds of compositions, or any 40 kinds of compositions, or any 41 kinds of compositions, or any 42 kinds of compositions, any 43 kinds of compositions, any 44 kinds of compositions, or whole composition.

Method : comprehensive preceding method and method .

During said method application, the amount of feeding of adding of animal is controlled its whole forage grass or/and the 1%-30%(of forage volume adds feed thing, under state that forage grass or feedstuff moisture content are about 14%).Between animal is butchered the previous moon to 3 day, advise that progressively using heavy dose to add feeds; Before animal is butchered, can add that to feed thing quantity-unlimiting to above-mentioned within 3 days, allow its free choice feeding, even lure that animal searches for food in a large number into, have a mind to allow some compositions of these materials of animal body accumulation.

Embodiment 3

The chitting piece of grass is added in the extraction glue juice water of on the make medicine colloid, especially Colla Corii Asini, as any one composition in Fructus Setariae Germinatus, Fructus Hordei Germinatus (comprising Semen Fagopyri Esculenti and Radix Et Rhizoma Fagopyri Tatarici), Fructus Setariae Germinatus, or two kinds, or whole composition.The Fructus Setariae Germinatus added in extraction glue juice operation, Fructus Hordei Germinatus (comprising Semen Fagopyri Esculenti and Radix Et Rhizoma Fagopyri Tatarici), Fructus Setariae Germinatus amount are: the germination thing of every 100 kilograms of raw material skins 2-10 kilogram of dry granule.

Can quantity-unlimitingly add in bubble skin operation.

Should starch with fresh bud, the specification of germination is advisable with just existing green.

Especially the germination thing using Radix Et Rhizoma Fagopyri Tatarici is suitable for, after germinateing, its stem and leaf suitable length is at 5-10 centimetre, find Radix Et Rhizoma Fagopyri Tatarici stem and leaf to coordinate with Colla Corii Asini can strengthen Colla Corii Asini physical strength profiting, continuous spirit, sharp knowledge, sending down the abnormal ascending QI, wide intestinal, stomach invigorating, control choke eat, carbuncle, hemostasis lose the functions such as nauseating, comprehensive function comparatively can contrast Ah's Colla Corii Asini raising drug effect 12% to 14%.

Embodiment 4

To produce the bubble skin of Chinese medicine colloid, unhairing, cut skin, wash skin, skin of picking up, extract glue juice carry out electric field/magnetization treatment with water, steam.Method and apparatus can with reference to Chinese patent literature CN 2401539Y or CN 1740098A.

Embodiment 5

When producing Colla Corii Asini, the container of holding rubber is placed in the parcel of quicklime or Gypsum Fibrosum preparata, then holding the container exterior parcel heat-insulating heat-preserving material of quicklime, is used for extracting or concentrated glue juice.When adopting this method, in order to improve the thermal efficiency, suggestion adopts decompressor to extract vapours.A beneficial effect of employing this method is: because do not use fiery class methods when extraction or concentrated glue juice, show according to theory of Chinese medical science and practice, the Colla Corii Asini that this method is made can reduce the upper bad temper of Colla Corii Asini finished product, is generally because can reduce the warm nature of Colla Corii Asini.

The container extracting glue juice can be pressurized equipment, and at upper vessel portion priming valve is set with arranging at bottom of window and puts glue valve, the middle and lower part setting of container can filter the filtering layer of glue juice, when glue juice can extract, open bottom valve and release glue, continue to boil after upper valve adds water.

Embodiment 6

In the adjuvant oils and fats used when producing Colla Corii Asini, add litsea cubeba oil or/and perilla oil, ratio can substitute all, or substitutes 0.1% to 99%.Or, do not reduce the use amount of original oils and fats, add litsea cubeba oil or/and perilla oil 0.1% to 100% by original oil quantity.

In order to reduce the cost of litsea cubeba oil, litsea cubeba oil can be reclaimed by the method for distillation litsea cubeba oil.

Embodiment 7

When producing Colla Corii Asini, by the genitals of animal as one of raw materials for production.By the kidney of animal domestic animal, birds, penis, as Ren caprae seu ovis Testis Et penis Caprae seu Ovis, Testis et Pentis Canis Penis et testis canitis, Ren Tigris Penis et testis Tigris, leopard kidney leopard whip, Testis Et penis Equi Testis Et penis Equi, Testis et penis Gallus domesticus, Ren Bovis seu Bubali Testis Et penis Bovis seu Bubali, Penis et testis sus domestica, Testis et penis callorhini, Penis et testis cervi Penis et testis cervi.Every 100 kilograms of Colla Corii Asini raw material animal skins class proportioning animals' reproduction organ fresh goods 5-20 kilogram.Product largest benefit that this method is made is: can improve with expansion Colla Corii Asini to the effect of male's sexual, the effectiveness strengthening the Yang strengthening function increasing Colla Corii Asini improves 15% to 25%.

Embodiment 8

Above-described embodiment, can comprehensive two or more enforcement, or all comprehensively implement.During the two or more enforcement of compound, can improve the quality of products during more single enforcement and function effectiveness 5% to 9%.

Embodiment 9

With Corii Bovis seu Bubali, Corii Sus domestica for raw material production Colla Corii Asini time, embodiment 1 can be adopted, or embodiment 2, or embodiment 7, also can by embodiment 1, embodiment 2, this three kinds of embodiment free generalizations two kinds enforcement of embodiment 7, or all comprehensive enforcement, can be able to improve the quality of products and function effectiveness 8% to 12% during more single enforcement.

Embodiment 10

If wish to produce the Colla Corii Asini strengthening antitumor function, emphasis adapted Ganoderma, Grifola frondosa, Marasmius androsaceus (L.ex Fr.) Fr., Phellinus igniarius (L. ex Fr.) Quel. etc.

Embodiment 11

If wish that Colla Corii Asini is for middle-aged male consumption, reuses Cordyceps and succedaneum, Radix Morindae Officinalis, Herba Cistanches, Rhizoma Curculiginis, the Cortex Eucommiae, Radix Dipsaci, Rhizoma Cibotii, Rhizoma Drynariae, Fructus Psoraleae, Fructus Alpiniae Oxyphyllae, Semen Juglandis, Semen Cuscutae, Semen Astragali Complanati, Herba Cynomorii, fragrant-flowered garlic, the Actinolitum etc. of strengthening yang and invigorating kidney effect.

Embodiment 12

If wish that Colla Corii Asini is for female consumption, emphasis coordinates tool to enrich blood, pacifies the Herba Leonuri, Folium Artemisiae Argyi, Schizophyllum commune Franch．, Auricularia, Herba Limonii Gmelinii, Radix Angelicae Sinensis, the Radix Astragali etc. of (tune) warp, YIN nourishing effect.

Embodiment 13

If wish that Colla Corii Asini is for old people market, emphasis coordinate have calm the nerves, the Hericium erinaceus (Bull. Ex Fr.) Pers., armillaria mellea, Radix Adenophorae (Radix Glehniae) etc. of YIN nourishing, aid digestion effect.

Embodiment 14

When the concentrated glue juice operation that Colla Corii Asini is produced, carry out electric field treatment to glue juice, the glue juice being about to concentrate is placed in electric field.

Embodiment 15

Edible and medical fungi trace element enrichment technology can be adopted, when artificial culture's edible and medical fungi, after inorganic Ge, selenium etc. are converted into organic germanium, selenium by edible and medical fungi, again the sporophore of this type of edible and medical fungi is used for the present invention, because adding organic germanium and organic selenium content in medicine edible fungi, the medicinal function of product greatly can be improved.

Supplemental instruction: described in the present invention and " Colla Corii Asini " that arrive, obligee thinks to be necessary the implication of " Colla Corii Asini " to extend to own " Chinese medicine colloid ", refer to that with animal skins, bone, first, angle etc. be raw material, get colloid with decocting, be condensed into dry gluey oral preparations.In the present invention, only in order to express easily, use " Colla Corii Asini " word.When obligee of the present invention advocates right, the implication of Colla Corii Asini can be expanded to " Chinese medicine colloid ", comprise but be limited to: hide glue, angle glue, osseocolla, nail gelatin, other all animal drug containing protein, temper through decocting and make colloid, if COLLA BOVIS class is with the colloid of beef through tempering, as turtle and deer glue, with Carapax et Plastrum Testudinis and Cornu Cervi for raw material, the mixing colloid of jointly tempering; The colloid etc. mixed with Colla Plastri Testudinis and Colla cornus cervi in addition.

Claims (10)

1. a Chinese medicine colloid, refers more particularly to one animal skins, bone, first, angle is primary raw material, containing edible and medical fungi, and sugar, oils and fats, and wine is adjuvant, become dry gluey, granule, liquid, the oral preparations of powdery, is characterized in that in colloid containing Ganoderma, Lentinus Edodes, Hericium erinaceus (Bull. Ex Fr.) Pers., Chinese scholartree bolt bacterium, Poria, Polyporus, Coriolous Dersicolor (Fr.) Quel, Marasmius androsaceus (L.ex Fr.) Fr., armillaria mellea, Armillariella tabescens, Cordyceps, Cordyceps militaris (L.) Link., Tremella, Flammulina velutiper (Fr.) Sing, Auricularia, Grifola frondosa, Pleurotus ulmarius (Bullex Franch) Quel fungus, Schizophyllum commune Franch．, red edge intends shelf fungus, cephalosporium sinensis, peacilomyce hepiahi bacterium, Paecilomyces gunnii, Fructus Litseae, Caulis Bambusae In Taeniam, Phellinus igniarius (L. ex Fr.) Quel., any one composition in Auricularia, or any two kinds of compositions, or any three kinds of compositions, or any four kinds of compositions, or any five kinds of compositions, or any six kinds of compositions, or any seven kinds of compositions, or any eight kinds of compositions, or any nine kinds of compositions, or any ten kinds of compositions, or any 11 kinds of compositions, or any 12 kinds of compositions, or any 13 kinds of compositions, or any 14 kinds of compositions, or any 15 kinds of compositions, or any 16 kinds of compositions, or any 17 kinds of compositions, or any 18 kinds of compositions, or any 19 kinds of compositions, or any 20 kinds of compositions, or any 21 kinds of compositions, or any 22 kinds of compositions, or whole composition.

2. the production method of Chinese medicine colloid as claimed in claim 1, is especially the production method of this Chinese medicine colloid primary raw material, adds feeding medicinal fungus, or/and some Chinese herbal medicine, it is characterized in that in these animal processes of raising to these animals:

produce in the process of Chinese medicine colloid primary raw material to add and feed Ganoderma, Lentinus Edodes, Hericium erinaceus (Bull. Ex Fr.) Pers., Chinese scholartree bolt bacterium, Poria, Polyporus, Coriolous Dersicolor (Fr.) Quel, Marasmius androsaceus (L.ex Fr.) Fr., armillaria mellea, Armillariella tabescens, Cordyceps, Cordyceps militaris (L.) Link., Tremella, Flammulina velutiper (Fr.) Sing, Auricularia, Grifola frondosa, Pleurotus ulmarius (Bullex Franch) Quel fungus, Schizophyllum commune Franch．, red edge intends shelf fungus, cephalosporium sinensis, peacilomyce hepiahi bacterium, Paecilomyces gunnii, Omphalia, Caulis Bambusae In Taeniam, Phellinus igniarius (L. ex Fr.) Quel., any one composition in Auricularia, or any two kinds of compositions, or any three kinds of compositions, or any four kinds of compositions, or any five kinds of compositions, or any six kinds of compositions, or any seven kinds of compositions, or any eight kinds of compositions, or any nine kinds of compositions, or any ten kinds of compositions, or any 11 kinds of compositions, or any 12 kinds of compositions, or any 13 kinds of compositions, or any 14 kinds of compositions, or any 15 kinds of compositions, or any 16 kinds of compositions, or any 17 kinds of compositions, or any 18 kinds of compositions, or any 19 kinds of compositions, or any 20 kinds of compositions, or any 21 kinds of compositions, or any 22 kinds of compositions, or whole composition, or

produce in the process of Chinese medicine colloid primary raw material to add and feed Fructus Crataegi, Massa Medicata Fermentata, Fructus Hordei Germinatus, Fructus Setariae Germinatus, Radix Ginseng, Radix Panacis Quinquefolii, Radix Codonopsis, the Radix Astragali, Rhizoma Dioscoreae, Radix Angelicae Sinensis, Radix Rehmanniae, Radix Polygoni Multiflori, Arillus Longan, Radix Morindae Officinalis, Herba Cistanches, Rhizoma Curculiginis, the Cortex Eucommiae, Radix Dipsaci, Rhizoma Cibotii, Rhizoma Drynariae, Fructus Psoraleae, Fructus Alpiniae Oxyphyllae, Semen Juglandis, Semen Cuscutae, Semen Astragali Complanati, Herba Cynomorii, fragrant-flowered garlic, Actinolitum, Radix Adenophorae (Radix Glehniae), Radix Ophiopogonis, Radix Asparagi, Herba Dendrobii, Rhizoma Polygonati Odorati, Rhizoma Polygonati, Bulbus Lilii, Fructus Lycii, Fructus Mori, Herba Ecliptae, Fructus Ligustri Lucidi, Semen Sesami Nigrum, Herba Leonuri, Fructus Litseae, Folium Artemisiae Argyi, Herba Limonii Gmelinii, any one composition in Herb Gynostemmae Pentaphylli, or any two kinds of compositions, or any three kinds of compositions, or any four kinds of compositions, or any five kinds of compositions, or any six kinds of compositions, or any seven kinds of compositions, or any eight kinds of compositions, or any nine kinds of compositions, or any ten kinds of compositions, or any 11 kinds of compositions, or any 12 kinds of compositions, or any 13 kinds of compositions, or any 14 kinds of compositions, or any 15 kinds of compositions, or any 16 kinds of compositions, or any 17 kinds of compositions, or any 18 kinds of compositions, or any 19 kinds of compositions, or any 20 kinds of compositions, or any 21 kinds of compositions, or any 22 kinds of compositions, or any 23 kinds of compositions, or any 24 kinds of compositions, or any 25 kinds of compositions, or any 26 kinds of compositions, or any 27 kinds of compositions, or any 28 kinds of compositions, or any 29 kinds of compositions, or any 30 kinds of compositions, or any 31 kinds of compositions, or any 32 kinds of compositions, or any 33 kinds of compositions, or any 34 kinds of compositions, or any 35 kinds of compositions, or any 36 kinds of compositions, or any 37 kinds of compositions, or any 38 kinds of compositions, or any 39 kinds of compositions, or any 40 kinds of compositions, or any 41 kinds of compositions, or any 42 kinds of compositions, any 43 kinds of compositions, any 44 kinds of compositions, or whole composition, or

produce in the process of Chinese medicine colloid primary raw material add feed aforementioned in any one, or several, or all after coordinate again in any one, or several, or all.

3. the production method of Chinese medicine colloid as claimed in claim 1, refer more particularly to a kind of steep skin, unhairing, cut skin, wash skin, skin of picking up, extract glue juice with water, steam, its spy is characterised in that:

to these processes described with water, carry out magnetization treatment with vapour; Or

any one composition in grass Fructus Setariae Germinatus, Fructus Hordei Germinatus, Fructus Setariae Germinatus can be contained in the use water of these processes, or two kinds, or whole composition.

4. the production method of Chinese medicine colloid as claimed in claim 1, refers more particularly to adjuvant oils and fats, it is characterized in that containing Fructus Litseae composition in described oils and fats, or the ratio containing litsea cubeba oil accounts for 1% to 100%.

5. Chinese medicine colloid production method as claimed in claim 1, is characterized in that in glue formulation manufacturing processes, by animals' reproduction organ as one of raw materials for production.

6. Chinese medicine colloid production method as claimed in claim 8, be described animals' reproduction organ, it is characterized in that referring to: the kidney of domestic animal, birds, penis, as Ren caprae seu ovis Testis Et penis Caprae seu Ovis, Testis et Pentis Canis Penis et testis canitis, Ren Tigris Penis et testis Tigris, leopard kidney leopard whip, Testis Et penis Equi Testis Et penis Equi, Testis et penis Gallus domesticus, Ren Bovis seu Bubali Testis Et penis Bovis seu Bubali, Penis et testis sus domestica, Testis et penis callorhini, Penis et testis cervi Penis et testis cervi.

7. Chinese medicine colloid as claimed in claim 1; be a kind of Colla Corii Asini with antitumor action made for primary raw material with donkey skin, Corii Sus domestica, Corii Bovis seu Bubali, it is characterized in that in described Colla Corii Asini containing one or more in Ganoderma, Lentinus Edodes, Hericium erinaceus (Bull. Ex Fr.) Pers., Chinese scholartree bolt bacterium, Poria, Polyporus, Coriolous Dersicolor (Fr.) Quel, Marasmius androsaceus (L.ex Fr.) Fr., armillaria mellea, Armillariella tabescens, Cordyceps, Cordyceps militaris (L.) Link., Tremella, Flammulina velutiper (Fr.) Sing, Auricularia, Grifola frondosa, Pleurotus ulmarius (Bullex Franch) Quel fungus, Schizophyllum commune Franch．, red edge plan shelf fungus, cephalosporium sinensis, peacilomyce hepiahi bacterium, Paecilomyces gunnii, Caulis Bambusae In Taeniam, Phellinus igniarius (L. ex Fr.) Quel., Auricularia.

8. the production method of Chinese medicine colloid as claimed in claim 1, refer more particularly to a kind of bubble skin, unhairing, cut skin, wash skin, to pick up skin, that extracts glue juice uses water, its spy is characterised in that described using in water containing Ganoderma, Lentinus Edodes, Hericium erinaceus (Bull. Ex Fr.) Pers., Chinese scholartree bolt bacterium, Poria, Polyporus, Coriolous Dersicolor (Fr.) Quel, Marasmius androsaceus (L.ex Fr.) Fr., armillaria mellea, Armillariella tabescens, Cordyceps, Cordyceps militaris (L.) Link., Tremella, Flammulina velutiper (Fr.) Sing, Auricularia, Grifola frondosa, Pleurotus ulmarius (Bullex Franch) Quel fungus, Schizophyllum commune Franch．, red edge intends shelf fungus, cephalosporium sinensis, peacilomyce hepiahi bacterium, Paecilomyces gunnii, Caulis Bambusae In Taeniam, Phellinus igniarius (L. ex Fr.) Quel., any one in Auricularia, or two kinds, or three kinds, or four kinds, or five kinds, or by that analogy to whole.

9. the production method of Chinese medicine colloid as claimed in claim 1, refers more particularly to primary raw material donkey skin Corii Sus domestica, the Corii Bovis seu Bubali of producing Colla Corii Asini and substitutes, it is characterized in that:

preparing the animal pig for doing Colla Corii Asini raw material, in the growth course of cattle live body, add and feed Ganoderma, Lentinus Edodes, Hericium erinaceus (Bull. Ex Fr.) Pers., Chinese scholartree bolt bacterium, Poria, Polyporus, Coriolous Dersicolor (Fr.) Quel, Marasmius androsaceus (L.ex Fr.) Fr., armillaria mellea, Armillariella tabescens, Cordyceps, Cordyceps militaris (L.) Link., Tremella, Flammulina velutiper (Fr.) Sing, Auricularia, Grifola frondosa, Pleurotus ulmarius (Bullex Franch) Quel fungus, Schizophyllum commune Franch．, red edge intends shelf fungus, cephalosporium sinensis, peacilomyce hepiahi bacterium, Paecilomyces gunnii, Caulis Bambusae In Taeniam, Phellinus igniarius (L. ex Fr.) Quel., Auricularia Fructus Crataegi, Massa Medicata Fermentata, Fructus Hordei Germinatus, Fructus Setariae Germinatus, Radix Ginseng, Radix Panacis Quinquefolii, Radix Codonopsis, the Radix Astragali, Rhizoma Dioscoreae, Radix Angelicae Sinensis, Radix Rehmanniae, Radix Polygoni Multiflori, Arillus Longan, Radix Morindae Officinalis, Herba Cistanches, Rhizoma Curculiginis, the Cortex Eucommiae, Radix Dipsaci, Rhizoma Cibotii, Rhizoma Drynariae, Fructus Psoraleae, Fructus Alpiniae Oxyphyllae, Semen Juglandis, Semen Cuscutae, Semen Astragali Complanati, Herba Cynomorii, fragrant-flowered garlic, Actinolitum, Radix Adenophorae (Radix Glehniae), Radix Ophiopogonis, Radix Asparagi, Herba Dendrobii, Rhizoma Polygonati Odorati, Rhizoma Polygonati, Bulbus Lilii, Fructus Lycii, Fructus Mori, Herba Ecliptae, Fructus Ligustri Lucidi, Semen Sesami Nigrum, Herba Leonuri, Fructus Litseae, Folium Artemisiae Argyi, Herba Limonii Gmelinii, Herb Gynostemmae Pentaphylli, add feed the kind of these materials can be wherein any one, also can be two kinds wherein, or three kinds, or four kinds, by that analogy to all, butcher rear bark fetching, partly or entirely substitute the raw materials for production of donkey skin as Colla Corii Asini, or

with Corii Sus domestica, Corii Bovis seu Bubali partly or entirely substitutes the bubble skin that donkey skin makes Colla Corii Asini, unhairing, cut skin, wash skin, to pick up skin, that extracts glue juice contains Ganoderma with in water, Lentinus Edodes, Hericium erinaceus (Bull. Ex Fr.) Pers., Chinese scholartree bolt bacterium, Poria, Polyporus, Coriolous Dersicolor (Fr.) Quel, Marasmius androsaceus (L.ex Fr.) Fr., armillaria mellea, Armillariella tabescens, Cordyceps, Cordyceps militaris (L.) Link., Tremella, Flammulina velutiper (Fr.) Sing, Auricularia, Grifola frondosa, Pleurotus ulmarius (Bullex Franch) Quel fungus, Schizophyllum commune Franch．, red edge intends shelf fungus, cephalosporium sinensis, peacilomyce hepiahi bacterium, Paecilomyces gunnii, Caulis Bambusae In Taeniam, Phellinus igniarius (L. ex Fr.) Quel., any one in Auricularia, or two kinds, or three kinds, or four kinds, or five kinds, by that analogy to whole.

10. a Colla Corii Asini, is characterized in that the chitting piece composition containing grass.