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CN107714559A - One kind is without anti-corrosion deep water supplement skin care item - Google Patents

One kind is without anti-corrosion deep water supplement skin care item Download PDF

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Publication number
CN107714559A
CN107714559A CN201711210561.4A CN201711210561A CN107714559A CN 107714559 A CN107714559 A CN 107714559A CN 201711210561 A CN201711210561 A CN 201711210561A CN 107714559 A CN107714559 A CN 107714559A
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skin
care item
skin care
deep water
water supplement
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曾万祥
覃敢为
陈海
黄娜
曾嘉
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Cosmetics (AREA)

Abstract

The invention provides one kind NMF and skin conditioning agent are included without anti-corrosion deep water supplement skin care item, the preparing raw material of the skin care item;The NMF includes carbohydrate isomer and Sodium Hyaluronate;The skin conditioning agent includes hydrolysis fibroin.Skin care item of the present invention employ carbohydrate isomer, hydrolyze outer skin moisturizing conditioning combination in fibroin and Sodium Hyaluronate, the internal conditioning by hydrolyzing fibroin and Sodium Hyaluronate, the albumen moisture of skin follicle lipid layer supplement skin losses can not only be penetrated into, skin elasticity can more be strengthened, make skin tender smooth.And the outside moisture that outflow is pinned using carbohydrate isomer, make the permanent water of skin tender, deep layer moistens moisturizing.So NMF and skin conditioning agent compounding, interior outer facies association, not only make the lasting moisturizing of skin inner layer, can also further prevent the loss of moisture, anti-aging on surface.

Description

One kind is without anti-corrosion deep water supplement skin care item
Technical field
The present invention relates to a kind of skin care item, and in particular to one kind is without anti-corrosion deep water supplement skin care item.
Background technology
With the economic development and improvement of people's living standards, people are not concerned only with the health of own bodies, itself Beauty is increasingly becoming the focus of concern.In particular with the quickening of people's rhythm of life, modern society environment air pollution day It is increasingly acute, cause the various skin problems such as thick pore, facial oiliness, colour of skin exception, wrinkle of skin occur.In order to subtract Delay and solve the appearance of these skin problems, people are furtherd investigate in medical cosmetology field always, are entered using various methods Row preserving moisture and protecting skin, but it is often ineffective.In existing cosmetics, also there are many moisturizers, but also due to moisturizing Time is short, can not meet the needs of skin deep moisturizing, be also easy to produce it is allergic and preservative use so that skin by The problems such as stimulation, by user without being chosen.Particularly in sensitive crowd's problem, produced after it is allergic, to patient Bring and have big pain, therefore for a long time, people thirst for finding always one kind can deep layer beautifying face, preserving moisture, excellent performance of keeping humidity, Good antiallergic performance and naturally without corrosion-resistant emulsion skin care item.
Such as application number 201510978194.7 discloses a kind of body lotion, it is made by following raw material:7-10 Part isopropyl palmitate, 0.4-0.6 part hexadecanols, 1-3 part saualanes, 0.2-0.4 part methyl p-hydroxybenzoates, 4-7 part honeybees Wax, 2-3 part Rosa Damascanas, 10-15 part deionized waters, 2-5 part glycerine, 10-15 part milk, olive oil 10-20 parts, the body lotion Composition employ methyl p-hydroxybenzoate as preservative, this preservative is carried to skin irritant, and is also had The use range of limitation;The nutrition being lost in using milk supplement skin, because milk is under the use of external application, absorbability is bad, The supplement for being lost in nutrition in vivo can not be met;By the moisture retention composition such as olive oil, glycerine, saualane, moisturizing skin, make skin Lubrication, but most greases is the moisturizing of skin outer layer, it is impossible to moisture is pinned well.
The content of the invention
There is provided a kind of without anti-corrosion deep water supplement shield it is an object of the invention to overcome the shortcomings of the prior art part Skin product.
To achieve the above object, the technical scheme taken of the present invention is:One kind is without anti-corrosion deep water supplement skin care item, the shield The preparing raw material of skin product includes NMF and skin conditioning agent;The NMF includes carbohydrate isomer and hyaluronic acid Sodium;The skin conditioning agent includes hydrolysis fibroin.
Carbohydrate isomer is colourless or micro- yellow transparency liquid, is referred to as water lock magnetite, is a kind of extract from cane suger The natural moisture preserving agent of class synthesis, has a moisturizing, assists moisture content incorporating collagen albumen, with up to moistening effect.It is a kind of to protect well Aqua and emollients.With reparation epidermal layer cells, lifting skin moisturizing ability, the isomerization manufactured via Measurement for Biochemistry D- glucans, have and the similar composition structure of human keratinous layer, can be combined using on skin with epsilon-amino acid functional group, just Firmly combined as magnetite, the long-acting hydromagnetic field energy power for maintaining skin of energy, there is good humidity of skin in skin applies some make up Regulatory function and long-acting moisture-keeping function, effect can be persistently untill cutin peel off naturally, and moisturizing is with slowing down stimulation;Produced in skin care Product play moisture-keeping function, antistatic property and anti-aging effect.
Sodium Hyaluronate is a kind of transparent colloid, can moment deep moisturizing, increase skin elasticity and tension force, help extensive The normal oil-water balance of multiple skin, improve skin of drying and relax.It is also a kind of important composition in skin, has epidermal tissue The function of reparation.When skin histology is exposed under UVB rays, skin can tan severely, inflammation, and dermal tissue can stop producing transparent Matter acid, while accelerate the fading rate of hyaluronic acid.Hyaluronic acid is largely present in the connective tissue and skin corium of human body, possesses Powerful water absorbing capacity and moisture-keeping functions, moreover it is possible to strengthen the prolonged water holding capacity of skin, elastic fibers and collagen can be helped Albumen is in the environment full of moisture, allows skin to show more flexible.
Hydrolyze fibroin, be the natural polymer fibrin extracted from silk, content account for silk 70%~ 80%, containing 18 kinds of amino acid, there is preferable affinity interaction to skin, protectiveness transparent membrane can be formed in skin surface, prevented Only injury of the thioglycolate salt to skin, the various nutrients needed for skin are supplemented, improve the gloss and elasticity of skin, Er Qietian Effective ingredient layering release in right fibroin liquid, 10 seconds infiltration skin skin coriums, effectively suppresses melanin generation, control Pigment.Promote collagen synthesis, activating cell, improve the immunity of cell, promote the metabolic rate of skin, help to repair Impaired skin histology, low and deep tired skin is made to add life again, so as to reduce whitening, the skin of gloss in very short time. Hydrolyze fibroin and also have following act on:Deep layer whitening:Go deep into skin bottom, fundamentally skin whitening and have no side effect;It is long Imitate moisturizing:The NMF factors decuple conventional plant or chemical NMF, continue efficiently to keep the skin wet to skin;Nourish conditioning:Infiltration Power is strong, nutrient necessary to be provided for skin, promotes cell metabolism, improves skin quality;Anti-ageing face living:Energy activating skin cell, improves Microcirculation, anti-ageing smoothing wrinkle, Yan Yuese living;It is anti-oxidant:External contamination is effective against, keeps skin ph balance, enhancing skin is exempted from Epidemic disease power.
Skin care item of the present invention employ interior outer skin moisturizing conditioning and combined, internal by hydrolyzing fibroin and transparent The conditioning of matter acid sodium, the albumen moisture of skin follicle lipid layer supplement skin losses can not only be penetrated into, can more strengthen skin elasticity, Make skin tender smooth.And the outside moisture that outflow is pinned using carbohydrate isomer, make the permanent water of skin tender, deep layer is moistened Moisturizing.So NMF and skin conditioning agent compounding, interior outer facies association, not only make the lasting moisturizing of skin inner layer, can also be Surface further prevents the loss of moisture, anti-aging.
It is former in the preparation of the skin care item as the preferred embodiment of no anti-corrosion deep water supplement skin care item of the present invention In material, the weight percentage of the carbohydrate isomer is 0.05~1%;The weight percentage of the Sodium Hyaluronate For 0.01~0.1%;The weight percentage of the hydrolysis fibroin is 0.1~1%.
When the carbohydrate isomer, Sodium Hyaluronate and hydrolysis fibroin use above-mentioned addition, skin can be made It is inside and outside to obtain the effect of preferable replenishing water and preserving moisture, add skin elasticity.
As the preferred embodiment of no anti-corrosion deep water supplement skin care item of the present invention, the NMF also includes Pork and beans Cool isopropyl propionate, 1,3 butylene glycol and glucan;In the preparing raw material of the skin care item, the weight of the isopropyl myristate It is 1~5% to measure percentage composition;The weight percentage of the 1,3 butylene glycol is 2~8%;The weight percent of the glucan Content is 1~3%.
Isopropyl myristate, belong to the synthetic fat of chemical manufacture, clearly, easily push open, the glutinous soapy feeling without general vegetable oil, because Molecule is small, easily penetrates into and grease type dirt is cleaned in pore, can play a part of moisturizing and skin care, suction of the skin to this product The property received is preferable, can effectively be contacted with hair follicle in cortex, penetrates into cortex depths, has to skin and fabulous permeate, moistens and soften Effect, and the active component in skin care item is brought into, give full play to the effect of active ingredient.Isopropyl myristate is in the present invention Middle to be used as cosmetic solvents and skin moisturizer, bleeding agent can increase the easy painting of product, and can reduce greasy feeling, there is softness Send out the effect of skin.
Using the isopropyl myristate of above-mentioned addition, 1,3 butylene glycol, glucan, carbohydrate isomer and transparent Matter acid is used as NMF, multiple moisturizing ingredient, the moisture being lost in can be supplemented from internal moist histocyte, delay the stream of moisture Lose, but also the natural moisture in the external world can be absorbed, lasting moisturizing, reach multiple moistening effect from inside to outside.
As the preferred embodiment of no anti-corrosion deep water supplement skin care item of the present invention, the skin conditioning agent also includes Hydrolyze algae extract and peony root extractive;In the preparing raw material of the skin care item, the weight hundred of the hydrolysis algae extract It is 0.1~0.8% to divide content;The weight percentage of the peony root extractive is 0.05~0.5%.
Hydrolyze containing a variety of sugar derivatives, mineral matter, phenols, trace element, amino acid etc. in algae extract, can be skin Skin provides nutrition, and moisturizing skin promotes epidermal growth, and increase increases the effect of cortex collagen.Tree peony root extracts Thing, amino acid, mineral matter, multivitamin and zinc, selenium and other trace elements rich in needed by human body, there is powerful work of releiving With the activity of melanin enzyme can be reduced in skin keratinocytes, so as to help to suppress to produce melanin;With antibacterial, disappear Inflammation effect;The Lymphatic Circulation of skin is stimulated, makes skin more glossy, improves skin quality, after continuing use, skin can be allowed slowly to wave Not obscure with coarse, skin is beautiful, water profit.Except containing hydrolyzed wheat protein in skin care item of the present invention, water also added Algae extract and peony root extractive are as skin conditioning agent, in the common of NMF carbohydrate isomer and Sodium Hyaluronate More nutrition can be provided for skin under effect, reach more preferable conditioning effect, moistening effect is long-acting persistently.
As the preferred embodiment of no anti-corrosion deep water supplement skin care item of the present invention, the hydrolysis fibroin, water Solution algae extract and the weight ratio of peony root extractive are:Hydrolyze fibroin:Hydrolyze algae extract:Peony root extractive= 3:3:1。
When hydrolysis fibroin, hydrolysis algae extract and the peony root extractive use said ratio, it can cooperate, Reach the effect of the conditioning skin of Synergistic.
As the preferred embodiment of no anti-corrosion deep water supplement skin care item of the present invention, the preparing raw material of the skin care item Also include emulsifying agent, emollient, thickener and antiseptic substitute;In the preparing raw material of the skin care item, the emulsifying agent Weight percentage be 0.5~1.3%;The weight percentage of the emollient is 2~10%;The weight of the thickener Percentage composition is 0.1~1%;The weight percentage of the antiseptic substitute is 0.01~1%.
As the preferred embodiment of no anti-corrosion deep water supplement skin care item of the present invention, the antiseptic substitute is 1, The mixture of 2- hexylene glycols, propane diols and decoyl hydroximic acid.
The use of preservative is extremely common in cosmetics, but traditional preservatives have certain toxicity, usage amount by Limitation, does not reach preferable antiseptic effect.Excessive or inappropriate preservative even can make epidermal cell developmental immaturity, structure Loosely, so that epidermis is thinning, easily declined by environmental stimuli, phylactic power defensive power, make skin follow the string gradually, easy generation relaxation, Microgroove, and constantly defect can then be bred by the Skin Cell of preservative infringement, make skin quality worse and worse.So traditional preservatives Harm is used so that existing washing product is badly in need of finding natural antiseptic agent or seted out to no added preservative direction.The present invention adopts The antiseptic substitute for being DM922 with marque, purchased from Guangdong Dimei Biological Technology Co., Ltd., without such as Form aldehyde release Thing, nipagin esters and OIT formaldehyde emission etc. limit the use of preservative, are a gentle anti-corrosions of comprehensive efficient natural Agent, its active component mainly have decoyl hydroximic acid, 1,2- hexylene glycols and propane diols, and excitant is low, and the compatibility of other components Preferably.
As the preferred embodiment of no anti-corrosion deep water supplement skin care item of the present invention, the emollient is ring five poly- two Methylsiloxane and saualane;The weight ratio of the ring five dimethyl silicone polymer and saualane is:The poly dimethyl silicon of ring five Oxygen alkane:Saualane=1~5:1~5.
As the preferred embodiment of no anti-corrosion deep water supplement skin care item of the present invention, the emulsifying agent is the smooth olive of sorb Olive oleate and cetearyl glucoside;The weight ratio of the smooth olive oleate of the sorb and cetearyl glucoside For:The smooth olive oleate of sorb:Cetearyl glucoside=3~7:2~6.
As the preferred embodiment of no anti-corrosion deep water supplement skin care item of the present invention, the thickener is acryloyl two N-methyltaurine ammonium/VP copolymers.
No anti-corrosion deep water supplement skin care item of the present invention, in addition to said components clearly require, in the lossless present invention Effect in the range of, other adjunct ingredients, such as pH adjusting agent, essence etc., those skilled in the art can be added or used to Conventional content can be selected according to conventional criteria.
Another object of the present invention, which also resides in, provides a kind of preparation method of above-mentioned no anti-corrosion deep water supplement skin care item, including Following steps:
(1) deionized water, is added in pot is emulsified, then heats to 80~85 DEG C, emulsifying agent is added, is evacuated to 0.5 After~0.75MPa, moderate-speed mixer is until be completely dissolved;Then NMF, emollient and thickener, moderate-speed mixer homogeneous are added 15~20min, 20min is incubated after homogeneous is complete, obtains component A;
(2), component A is cooled, temperature adds NMF when being down to 50 DEG C, stirs, and obtains component B;
(3), component B is cooled, temperature adds NMF and skin conditioning agent when being down to 45 DEG C, is well mixed, obtains Component C;
(4) 42 DEG C, are cooled to component C, adds antiseptic substitute, is well mixed, pH value is adjusted, adjusts to target and stick Degree, produces the no anti-corrosion deep water supplement skin care item.
The beneficial effects of the present invention are:It is of the present invention the invention provides one kind without anti-corrosion deep water supplement skin care item Skin care item employ carbohydrate isomer, hydrolyze outer skin moisturizing conditioning combination in fibroin and Sodium Hyaluronate, internal By hydrolyzing the conditioning of fibroin and Sodium Hyaluronate, the albumen of skin follicle lipid layer supplement skin losses can not only be penetrated into It moisture, can more strengthen skin elasticity, make skin tender smooth.And the outside moisture that outflow is pinned using carbohydrate isomer, Make that the permanent water of skin is tender, and deep layer moistens moisturizing.So NMF and skin conditioning agent compounding, interior outer facies association, not only make skin The lasting moisturizing of skin internal layer, it can also further prevent the loss of moisture, anti-aging on surface.
Embodiment
To better illustrate the object, technical solutions and advantages of the present invention, below in conjunction with specific embodiment to the present invention It is described further.
Embodiment 1
A kind of embodiment of no anti-corrosion deep water supplement skin care item of the present invention, includes the preparation of following weight percentage Raw material:NMF 10.3%, skin conditioning agent 0.7%, emulsifying agent 1%, emollient 6%, thickener 0.8%, preservative substitute The deionized water of thing 0.5%, citric acid 0.3% and surplus;
Wherein, the NMF is carbohydrate isomer, Sodium Hyaluronate, isopropyl myristate, 1,3-BDO And glucan;Weight percentage of each composition of institute's NMF in the preparing raw material of skin care item be:Carbohydrate isomer 0.2%;Sodium Hyaluronate 0.1%;Isopropyl myristate 3%;1,3 butylene glycol 5%;Glucan 2%;
The skin conditioning agent is hydrolysis fibroin, hydrolysis algae extract and peony root extractive;Protected skin condition Weight percentage of each composition of agent in the preparing raw material of skin care item be:Hydrolyze fibroin 0.3%;Hydrolyze algae extract 0.3%;Peony root extractive 0.1%;
The emulsifying agent is the smooth olive oleate of sorb and cetearyl glucoside;The smooth olive oleate of sorb and The weight ratio of cetearyl glucoside is:The smooth olive oleate of sorb:Cetearyl glucoside=1:1;The thickening Agent is AVC;
The emollient is ring five dimethyl silicone polymer and saualane;The ring five dimethyl silicone polymer and saualane Weight ratio be:Ring five dimethyl silicone polymer:Saualane=1:1;
The thickener is AVC;
The antiseptic substitute is the mixture of 1,2- hexylene glycols, propane diols and decoyl hydroximic acid.
Preparation method without anti-corrosion deep water supplement skin care item described in the present embodiment, comprises the following steps:
(1) deionized water, is added in pot is emulsified, then heats to 80~85 DEG C, emulsifying agent is added, is evacuated to 0.5 After~0.75MPa, moderate-speed mixer is until be completely dissolved;Then add isopropyl myristate, ring five dimethyl silicone polymer, Saualane and AVC, moderate-speed mixer 15~20min of homogeneous, are incubated after homogeneous is complete 20min, obtain component A;
(2), component A is cooled, added when temperature is down to 50 DEG C scattered 1, the 2- butanediols of deionized water with thoroughly Bright matter acid sodium, stirs, and obtains component B;
(3), component B is cooled, temperature adds hydrolysis fibroin, carbohydrate isomer, Portugal when being down to 45 DEG C Glycan, hydrolysis algae extract and peony root extractive, are well mixed, obtain component C;
(4) 42 DEG C, are cooled to component C, adds antiseptic substitute, is well mixed, pH value is adjusted, adjusts to target and stick Degree, produces the no anti-corrosion deep water supplement skin care item.
Embodiment 2
A kind of embodiment of no anti-corrosion deep water supplement skin care item of the present invention, skin care item described in the present embodiment include following The preparing raw material of weight percentage:NMF 4.06%, skin conditioning agent 0.255, emulsifying agent 0.5%, emollient 10%, increasing Thick dose 1%, antiseptic substitute 0.01%, the deionized water of citric acid 0.3% and surplus;
Wherein, the NMF is carbohydrate isomer, Sodium Hyaluronate, isopropyl myristate, 1,3-BDO And glucan;Weight percentage of each composition of institute's NMF in the preparing raw material of skin care item be:Carbohydrate isomer 0.05%;Sodium Hyaluronate 0.01%;Isopropyl myristate 1%;1,3 butylene glycol 2%;Glucan 1%;
The skin conditioning agent is hydrolysis fibroin, hydrolysis algae extract and peony root extractive;Protected skin condition Weight percentage of each composition of agent in the preparing raw material of skin care item be:Hydrolyze fibroin 0.1%;Hydrolyze algae extract 0.1%;Peony root extractive 0.05%;
The emulsifying agent is the smooth olive oleate of sorb and cetearyl glucoside;The smooth olive oleate of sorb and The weight ratio of cetearyl glucoside is:The smooth olive oleate of sorb:Cetearyl glucoside=3:2;The thickening Agent is AVC;
The emollient is ring five dimethyl silicone polymer and saualane;The ring five dimethyl silicone polymer and saualane Weight ratio be:Ring five dimethyl silicone polymer:Saualane=1:1;
The thickener is AVC;
The antiseptic substitute is the mixture of 1,2- hexylene glycols, propane diols and decoyl hydroximic acid.
Preparation method without anti-corrosion deep water supplement skin care item described in the present embodiment is the same as embodiment 1.
Embodiment 3
A kind of embodiment of no anti-corrosion deep water supplement skin care item of the present invention, skin care item described in the present embodiment include following The preparing raw material of weight percentage:NMF 17.1%, skin conditioning agent 2.3%, emulsifying agent 1.3%, emollient 10%, increasing Thick dose 0.5%, antiseptic substitute 1%, the deionized water of citric acid 0.3% and surplus;
Wherein, the NMF is carbohydrate isomer, Sodium Hyaluronate, isopropyl myristate, 1,3-BDO And glucan;Weight percentage of each composition of institute's NMF in the preparing raw material of skin care item be:Carbohydrate isomer 1%;Sodium Hyaluronate 0.1%;Isopropyl myristate 5%;1,3 butylene glycol 8%;Glucan 3%;
The skin conditioning agent is hydrolysis fibroin, hydrolysis algae extract and peony root extractive;Protected skin condition Weight percentage of each composition of agent in the preparing raw material of skin care item be:Hydrolyze fibroin 1%;Hydrolyze algae extract 0.8%;Peony root extractive 0.5%;
The emulsifying agent is the smooth olive oleate of sorb and cetearyl glucoside;The smooth olive oleate of sorb and The weight ratio of cetearyl glucoside is:The smooth olive oleate of sorb:Cetearyl glucoside=7:6;The thickening Agent is AVC;
The emollient is ring five dimethyl silicone polymer and saualane;The ring five dimethyl silicone polymer and saualane Weight ratio be:Ring five dimethyl silicone polymer:Saualane=2:3;
The thickener is AVC;
The antiseptic substitute is the mixture of 1,2- hexylene glycols, propane diols and decoyl hydroximic acid.
Preparation method without anti-corrosion deep water supplement skin care item described in the present embodiment is the same as embodiment 1.
Embodiment 4
A kind of embodiment of no anti-corrosion deep water supplement skin care item of the present invention, skin care item described in the present embodiment include following The preparing raw material of weight percentage:NMF 11.55%, skin conditioning agent 1.1%, emulsifying agent 1.2%, emollient 6%, increasing Thick dose 0.6%, antiseptic substitute 0.5%, the deionized water of citric acid 0.3% and surplus;
Wherein, the NMF is carbohydrate isomer, Sodium Hyaluronate, isopropyl myristate, 1,3-BDO And glucan;Weight percentage of each composition of institute's NMF in the preparing raw material of skin care item be:Carbohydrate isomer 0.5%;Sodium Hyaluronate 0.05%;Isopropyl myristate 3%;1,3 butylene glycol 6%;Glucan 2%;
The skin conditioning agent is hydrolysis fibroin, hydrolysis algae extract and peony root extractive;Protected skin condition Weight percentage of each composition of agent in the preparing raw material of skin care item be:Hydrolyze fibroin 0.5%;Hydrolyze algae extract 0.4%;Peony root extractive 0.2%;
The emulsifying agent is the smooth olive oleate of sorb and cetearyl glucoside;The smooth olive oleate of sorb and The weight ratio of cetearyl glucoside is:The smooth olive oleate of sorb:Cetearyl glucoside=1:2;The thickening Agent is AVC;
The emollient is ring five dimethyl silicone polymer and saualane;The ring five dimethyl silicone polymer and saualane Weight ratio be:Ring five dimethyl silicone polymer:Saualane=1:5;
The thickener is AVC;
The antiseptic substitute is the mixture of 1,2- hexylene glycols, propane diols and decoyl hydroximic acid.
Preparation method without anti-corrosion deep water supplement skin care item described in the present embodiment is the same as embodiment 1.
Embodiment 5
A kind of embodiment of no anti-corrosion deep water supplement skin care item of the present invention, the preparation of skin care item described in the present embodiment are former Material and the difference of the content that the difference is that only each composition of skin conditioning agent of embodiment 1;Skin condition described in the present embodiment Agent is hydrolysis fibroin, hydrolysis algae extract and peony root extractive;System of the protected each composition of skin conditioning agent in skin care item It is for the weight percentage in raw material:Hydrolyze fibroin 0.3%;Hydrolyze algae extract 0.4%;Peony root extractive 0.1%.
Preparation method without anti-corrosion deep water supplement skin care item described in the present embodiment is the same as embodiment 1.
Embodiment 6
A kind of embodiment of no anti-corrosion deep water supplement skin care item of the present invention, the preparation of skin care item described in the present embodiment are former Material and the difference of the content that the difference is that only each composition of skin conditioning agent of embodiment 1;Skin condition described in the present embodiment Agent is hydrolysis fibroin, hydrolysis algae extract and peony root extractive;System of the protected each composition of skin conditioning agent in skin care item It is for the weight percentage in raw material:Hydrolyze fibroin 0.5%;Hydrolyze algae extract 0.2%;Peony root extractive 0.1%.
Preparation method without anti-corrosion deep water supplement skin care item described in the present embodiment is the same as embodiment 1.
Comparative example 1
A kind of comparative example of no anti-corrosion deep water supplement skin care item of the present invention, the preparation of skin care item described in this comparative example are former Material and the difference that the difference is that only NMF of embodiment 1, NMF described in this comparative example are free of carbohydrate isomer; But the total addition level of NMF is constant, i.e., skin care item described in this comparative example include the preparing raw material of following weight percentage:Protect Humectant 10.3%, skin conditioning agent 0.7%, emulsifying agent 10%, emollient 6%, thickener 0.8%, antiseptic substitute 0.5%th, the deionized water of citric acid 0.3% and surplus;
Wherein, the NMF is Sodium Hyaluronate, isopropyl myristate, 1,3-BDO and glucan;Institute's moisturizing Weight percentage of each composition of agent in the preparing raw material of skin care item be:Sodium Hyaluronate 0.1%;Isopropyl myristate 3.06%;1,3 butylene glycol 5.1%;Glucan 2.04%;
The skin conditioning agent, emulsifying agent, emollient, thickener and antiseptic substitute are identical with embodiment.
Preparation method without anti-corrosion deep water supplement skin care item described in this comparative example is the same as embodiment 1.
Comparative example 2
A kind of comparative example of no anti-corrosion deep water supplement skin care item of the present invention, the preparation of skin care item described in this comparative example are former Material and the difference that the difference is that only NMF of embodiment 1, NMF described in this comparative example are free of Sodium Hyaluronate;But protect The total addition level of humectant is constant, i.e., skin care item described in this comparative example include the preparing raw material of following weight percentage:NMF 10.3%th, skin conditioning agent 0.7%, emulsifying agent 10%, emollient 6%, thickener 0.8%, antiseptic substitute 0.5%, lemon The deionized water of lemon acid 0.3% and surplus;
Wherein, the NMF is carbohydrate isomer, isopropyl myristate, 1,3-BDO and glucan;Institute Weight percentage of each composition of NMF in the preparing raw material of skin care item be:Carbohydrate isomer 0.2%;Myristic acid Isopropyl ester 3.03%;1,3 butylene glycol 5.05%;Glucan 2.02%;
The skin conditioning agent, emulsifying agent, emollient, thickener and antiseptic substitute are identical with embodiment.
Preparation method without anti-corrosion deep water supplement skin care item described in this comparative example is the same as embodiment 1.
Comparative example 3
A kind of comparative example of no anti-corrosion deep water supplement skin care item of the present invention, the preparation of skin care item described in this comparative example are former Material and the difference that the difference is that only NMF of embodiment 1, NMF described in this comparative example are free of isopropyl myristate; But the total addition level of NMF is constant, i.e., skin care item described in this comparative example include the preparing raw material of following weight percentage:Protect Humectant 10.3%, skin conditioning agent 0.7%, emulsifying agent 10%, emollient 6%, thickener 0.8%, antiseptic substitute 0.5%th, the deionized water of citric acid 0.3% and surplus;
Wherein, the NMF is carbohydrate isomer, Sodium Hyaluronate, 1,3-BDO and glucan;Institute's moisturizing Weight percentage of each composition of agent in the preparing raw material of skin care item be:Carbohydrate isomer 0.28%;Sodium Hyaluronate 0.14%;1,3 butylene glycol 7.05%;Glucan 2.83%;
The skin conditioning agent, emulsifying agent, emollient, thickener and antiseptic substitute are identical with embodiment.
Preparation method without anti-corrosion deep water supplement skin care item described in this comparative example is the same as embodiment 1.
Comparative example 4
A kind of comparative example of no anti-corrosion deep water supplement skin care item of the present invention, the preparation of skin care item described in this comparative example are former Material and the difference that the difference is that only skin conditioning agent of embodiment 1, skin conditioning agent described in this comparative example is without hydrolysis silkworm Silk-fibroin;But the total addition level of skin conditioning agent is constant, i.e., skin care item described in this comparative example include following weight percentage Preparing raw material:NMF 10.3%, skin conditioning agent 0.7%, emulsifying agent 10%, emollient 6%, thickener 0.8%, preservative The deionized water of substitute 0.5%, citric acid 0.3% and surplus;
Wherein, the skin conditioning agent is hydrolysis algae extract and peony root extractive;Protected each composition of skin conditioning agent Weight percentage in the preparing raw material of skin care item is:Hydrolyze algae extract 0.53%;Peony root extractive 0.17%;
The NMF, emulsifying agent, emollient, thickener and antiseptic substitute are identical with embodiment.
Preparation method without anti-corrosion deep water supplement skin care item described in this comparative example is the same as embodiment 1.
Embodiment 7
No anti-corrosion deep water supplement skin care item described to embodiment 1~6 carry out Physico-chemical tests, and gained Testing index is as follows:
1st, character detects
The no anti-corrosion deep water supplement skin care item of embodiment 1~6 are that viscosity is suitable, are had good stability, smell is pure and fresh Milky lotion.
2nd, pH value detects
No anti-corrosion deep water supplement skin care item sampling described to embodiment 1~6, is determined with pH meter, measure pH value for 6.0~ 6.5。
3rd, viscosity number detects
No anti-corrosion deep water supplement skin care item sampling described to embodiment 1~6, is determined with viscosimeter, measures viscosity number 15000 ~20000.
4th, Detection of Stability
No anti-corrosion deep water supplement skin care item sampling described to embodiment 1~6, is encapsulated in transparence cosmetic bottle, point Be not placed in quartz lamp illumination, -15 DEG C, 5 DEG C, 25 DEG C, under 48 DEG C of experiment conditions, to outward appearance, fragrance, pH value, viscosity and other Project carries out the continuance test of 3 months by a definite date, sees whether bleed, layering, separation, precipitation, discoloration, peculiar smell, demulsification etc. occur Bad phenomenon, testing result show that the bad result of the above is not appeared in test process, illustrates that it has good stability.
5th, anaphylaxis is stimulated to detect
No anti-corrosion deep water supplement skin care item sampling described to embodiment 1~6, it is 18- that it is applied to 30 age brackets in right amount Near volunteer's ear basal part of the ear of 58 years old, 30min is observed, sees whether it phenomena such as redness, dermexanthesis, foaming occurs, observes result Show, all volunteers do not occur above-mentioned ill symptomses in 30min, illustrate that this product will not produce stimulation and allergy to skin Sex chromosome mosaicism.
7th, comprehensive using effect detection
Using opinion poll point system, by asking volunteer to try out the sample of embodiment 1~6 and comparative example 1~4 respectively, And fill in table on probation and carry out overall merit its using effect.Every group of embodiment sample chooses the volunteer 100 in all ages and classes stage Name (volunteer 50 and the volunteer 50 of 38~58 age levels that age level is 18~38) is as object on probation, aspiration Skin care item described in embodiment 1 are smeared after the daily morning and evening face cleaning of person, are used continuously three months, table on probation is filled in after on probation and is commented Point.Every using effect total score is 5 points in grade form:5 points are best results, are represented very satisfied;4 points be it is preferable, relatively It is satisfied;3 points are to receive;Less than the 3 points scopes for that cannot receive, every using effect average situation are shown in Table 1.
The embodiment 1~6 of table 1 and the skin care item items using effect average situation of comparative example 1~4
Using effect Moisture retention Skin elasticity Moisten persistence Deep water supplement It is nonirritant
Embodiment 1 4.96 4.93 4.96 4.96 5.00
Embodiment 2 4.88 4.86 4.85 4.86 5.00
Embodiment 3 4.94 4.93 4.95 4.94 5.00
Embodiment 4 4.95 4.90 4.94 4.95 5.00
Embodiment 5 4.92 4.88 4.90 4.91 5.00
Embodiment 6 4.90 4.89 4.91 4.89 5.00
Comparative example 1 4.86 4.89 4.82 4.86 5.00
Comparative example 2 4.84 4.86 4.88 4.85 5.00
Comparative example 3 4.86 4.89 4.87 4.86 5.00
Comparative example 4 4.90 4.85 4.91 4.89 5.00
Test result is as shown in table 1, the results showed that:Embodiment 1~6 and 1~4 skin care item of comparative example show as nothing Stimulate and cleannes are good.From the contrast of embodiment 1 and embodiment 5,6 as can be seen that changing the proportioning of skin conditioning agent, to shield The resultant effect tool of skin product has a certain impact, and embodiment 1 performs better, and illustrates the hydrolysis fibroin, hydrolysis algae extraction Thing and the weight ratio of peony root extractive are:Hydrolyze fibroin:Hydrolyze algae extract:Peony root extractive=3:3:When 1, Can make skin care item moistening effect and moisturizing effect more preferably.From the moistening effect of embodiment 1 and comparative example 1,2,4, increase skin The effect of elasticity, moist persistence and deep water supplement can be seen that using carbohydrate isomer, Sodium Hyaluronate and hydrolysis When three kinds of components matchings uses of fibroin more only use two of which composition, it can more reach preferable moisturizing, increase skin The effect of elasticity, and lasting moisturizing effect and deep water supplement effect, illustrate that three kinds of components matching uses can reach by interior And outer moisturizing moisturizing effect.Can be seen that isopropyl myristate from the contrast of embodiment 1 and comparative example 3 has necessarily Moisturizing and moisturizing effect.
Embodiment 8
To verify effect of the skin care item of the present invention in terms of moisturizing, to described in embodiment 1,5,6 and comparative example 1~4 Skin care item carry out skin moisture content test.
Select 140 healths, the volunteer without skin care item allergies, volunteer be the age between 40~55 years old, Men and women is unlimited, is divided into 8 groups, every group 20.After the daily morning and evening face cleaning of every group of volunteer, respectively using embodiment 1,5,6 and contrast 1~4 skin care item of example, application method are applied to eye circumference to take in right amount, gently smear by fully absorbing.Choose the face of volunteer Cheek area skin tests the moisture of skin after daily volunteer uses skin care item 30min using moisture of skin analyzer (SG-5D) Content.Continuous use 7 days, test result is shown in Table 2.
Table 2 uses the moisture test result of skin after embodiment 1,5,6 and the skin care item 30min of comparative example 1~4
Group First day Second day 3rd day 4th day 5th day 6th day 7th day Growth rate
Embodiment 1 15.6% 16.3% 16.8% 17.6% 20.5% 23.5% 25.0% 60.3%
Embodiment 5 16.6% 16.9% 17.6% 19.0% 20.9% 22.4% 25.2% 51.8%
Embodiment 6 15.2% 16.3% 17.9% 20.5% 21.6% 22.8% 23.9% 57.2%
Comparative example 1 16.2% 16.9% 17.5% 18.2% 19.5% 20.2% 21.0% 29.6%
Comparative example 2 15.9% 16.8% 17.5% 18.0% 19.2% 20.0% 21.2% 33.3%
Comparative example 3 15.3% 16.0% 17.2% 18.5% 19.3% 21.4% 22.1% 44.4%
Comparative example 4 15.8% 16.2% 17.6% 17.9% 18.9% 21.6% 23.5% 48.7%
It is can be seen that from the test result of table 2 using after skin care item of the present invention, the moisture of skin has significantly Increase, illustrates that skin care item of the present invention have the replenishing water and preserving moisture effect of preferable replenishing water and preserving moisture effect, especially embodiment 1 most It is good.It is better that the replenishing water and preserving moisture of embodiment 1 is can be seen that from the contrast of embodiment 1 and embodiment 5,6, illustrates the hydrolysis silkworm Silk-fibroin, hydrolysis algae extract and the weight ratio of peony root extractive are:Hydrolyze fibroin:Hydrolyze algae extract:Tree peony Root extract=3:3:When 1, it can make skin care item that there is more preferable moistening effect.From the test knot of embodiment 1 and comparative example 1,2,4 Fruit, which can be seen that to use using carbohydrate isomer, Sodium Hyaluronate and hydrolysis three kinds of components matchings of fibroin, more only to be made During with two of which composition, can more reach more preferable replenishing water and preserving moisture effect, illustrate three kinds of components matching uses can reach by Interior and outer moisturizing moisturizing effect.From the contrast of the test result of embodiment 1 and comparative example 3 as can be seen that isopropyl myristate Certain moisturizing and moisturizing effect can be played in skin care item of the present invention.
Finally, it should be noted that the above embodiments are merely illustrative of the technical solutions of the present invention rather than the present invention is protected The limitation of scope is protected, although being explained in detail with reference to preferred embodiment to the present invention, one of ordinary skill in the art should Understand, technical scheme can be modified or equivalent substitution, without departing from the essence of technical solution of the present invention And scope.

Claims (10)

1. one kind is without anti-corrosion deep water supplement skin care item, it is characterised in that the preparing raw material of the skin care item includes NMF and skin Skin conditioner;The NMF includes carbohydrate isomer and Sodium Hyaluronate;The skin conditioning agent includes hydrolysis silk Albumen.
2. as claimed in claim 1 without anti-corrosion deep water supplement skin care item, it is characterised in that in the preparing raw material of the skin care item In, the weight percentage of the carbohydrate isomer is 0.05~1%;The weight percentage of the Sodium Hyaluronate is 0.01~0.1%;The weight percentage of the hydrolysis fibroin is 0.1~1%.
3. as claimed in claim 1 without anti-corrosion deep water supplement skin care item, it is characterised in that the NMF also includes myristic acid Isopropyl ester, 1,3 butylene glycol and glucan;In the preparing raw material of the skin care item, the weight hundred of the isopropyl myristate It is 1~5% to divide content;The weight percentage of the 1,3 butylene glycol is 2~8%;The weight percentage of the glucan For 1~3%.
4. as claimed in claim 1 without anti-corrosion deep water supplement skin care item, it is characterised in that the skin conditioning agent is also comprising hydrolysis Algae extract and peony root extractive;In the preparing raw material of the skin care item, the weight percent of the hydrolysis algae extract contains Measure as 0.1~0.8%;The weight percentage of the peony root extractive is 0.05~0.5%.
5. as claimed in claim 4 without anti-corrosion deep water supplement skin care item, it is characterised in that the hydrolysis fibroin, hydrolysis algae Extract and the weight ratio of peony root extractive are:Hydrolyze fibroin:Hydrolyze algae extract:Peony root extractive=3:3: 1。
6. without anti-corrosion deep water supplement skin care item as any one of Claims 1 to 5, it is characterised in that the skin care item Preparing raw material also includes emulsifying agent, emollient, thickener and antiseptic substitute;In the preparing raw material of the skin care item, institute The weight percentage for stating emulsifying agent is 0.5~1.3%;The weight percentage of the emollient is 2~10%;The thickening The weight percentage of agent is 0.1~1%;The weight percentage of the antiseptic substitute is 0.01~1%.
7. as claimed in claim 6 without anti-corrosion deep water supplement skin care item, it is characterised in that the antiseptic substitute be 1,2- oneself The mixture of glycol, propane diols and decoyl hydroximic acid.
8. as claimed in claim 6 without anti-corrosion deep water supplement skin care item, it is characterised in that the emollient is the poly dimethyl of ring five Siloxanes and saualane;The weight ratio of the ring five dimethyl silicone polymer and saualane is:Ring five dimethyl silicone polymer: Saualane=1~5:1~5.
9. as claimed in claim 6 without anti-corrosion deep water supplement skin care item, it is characterised in that the emulsifying agent is the smooth olive oil of sorb Acid esters and cetearyl glucoside;The smooth olive oleate of the sorb and the weight ratio of cetearyl glucoside are:Mountain The smooth olive oleate of pears:Cetearyl glucoside=3~7:2~6.
10. as claimed in claim 6 without anti-corrosion deep water supplement skin care item, it is characterised in that the thickener is acryloyl diformazan Base taurine ammonium/VP copolymers.
CN201711210561.4A 2017-11-27 2017-11-27 One kind is without anti-corrosion deep water supplement skin care item Pending CN107714559A (en)

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CN111920704A (en) * 2020-08-14 2020-11-13 广东至臻生物医药有限公司 Double-layer moisturizing original solution and preparation method thereof
CN111956548A (en) * 2020-08-24 2020-11-20 耒阳市刘燕酿制生物科技有限公司 Preparation method of essence with whitening effect
CN111973467A (en) * 2020-09-09 2020-11-24 许文斌 Moisturizing emulsion based on ginseng polysaccharide and preparation method thereof
CN115475112A (en) * 2022-09-23 2022-12-16 上海纳米技术及应用国家工程研究中心有限公司 A facial mask containing low molecular sodium hyaluronate and silk fibroin and its preparation method

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