CN107693837A - The preparation and application of effective anti-bacterial lubricant outside a kind of tapon - Google Patents
The preparation and application of effective anti-bacterial lubricant outside a kind of tapon Download PDFInfo
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- CN107693837A CN107693837A CN201710979607.2A CN201710979607A CN107693837A CN 107693837 A CN107693837 A CN 107693837A CN 201710979607 A CN201710979607 A CN 201710979607A CN 107693837 A CN107693837 A CN 107693837A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/50—Lubricants; Anti-adhesive agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/18—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing inorganic materials
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/46—Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
- A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/452—Lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/62—Encapsulated active agents, e.g. emulsified droplets
- A61L2300/622—Microcapsules
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2420/00—Materials or methods for coatings medical devices
- A61L2420/02—Methods for coating medical devices
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2420/00—Materials or methods for coatings medical devices
- A61L2420/06—Coatings containing a mixture of two or more compounds
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Inorganic Chemistry (AREA)
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- Absorbent Articles And Supports Therefor (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The preparation and application of effective anti-bacterial lubricant outside a kind of tapon, belong to function hygienic material preparation field.Its technical scheme is：Antibacterial metal oxide, a small amount of rare-earth mineral prime element and complexing agent are mixed with certain proportion, are then gradually added drop-wise under agitation in oleaginous system, forms stable water-in-oil system；30 120min are reacted in 120 170 DEG C of reactors, are cooled down, centrifuges and removes precipitum, produce the lubricant with antibacterial action；Anti-bacterial lubricant is sprayed on tapon outer tube, facilitates conduit to be implanted into, while has antibacterial action, effectively overcomes the allergic problem and the caused precipitation discoloration problem of inorganic silver ion antimicrobial agent of the organic antibacterial agent being commonly used.Outer tube microorganism is removed, its lubricity is improved, there are extremely strong antibacterial functions, and to human body without any stimulation and allergy, safety and environmental protection；, can be efficiently against worry exceeded to tapon outer tube microorganism at present especially as tapon outer tube lubricant.
Description
Technical field
Application the invention discloses a kind of preparation of anti-bacterial lubricant and on catheter type tapon outer tube, belongs to work(
Can hygienic material preparation field.
Background technology
Do not influence to wear clothes and move when the tapon of catheter type is due to use, receive the favor of many people, American-European female
Property using more, in the U.S., the women for having 42% uses tapon.Because Asian does not like suppository, cotton wool traditionally
Bar is using seldom in the women of Asian countries, and in China, only 2% women uses tapon.Main cause is many
Women uses first, from want of experience or plastic catheter wall slickness it is bad, it is difficult to correctly implant；Secondly many female
Property think that tapon and plastic catheter wall are not hygienic enough, worry bacterium be incorporated into intrauterine and cause to infect, make infection
Chance increase, in some instances it may even be possible to cause toxic shock syndrome.The use of anti-bacterial lubricant can make implantation smooth, eliminate simultaneously
The misgivings that people introduce to bacterium.
The research of anti-bacterial lubricant is not a lot, typically without the lubrication of the tapon external application pipe specifically for catheter type
Agent.Such as Chinese patent 201510214935.4, there is provided a kind of method for preparing lubricant for human body, by polyacrylamide tree
Fat is well mixed after being sufficiently mixed with glycerine, propane diols, 1,3-BDO with aqueous medium, and is added preservative and obtained, lubrication
Property good, colorless and odorless, property is gentle, while also has antibacterial, antiinflammatory action, and all ingredients used can be dissolved in water, just
In cleaning, human skin will not be remained in, is a kind of safe and effective lubricant.Chinese patent 201610947042.5, is carried
Supplied a kind of preparation method of lubricant, specific content effect under, thickener, lubricant, NMF, pH value regulator,
Preservative, surplus are sterilized water, mutually synergy, and there is very strong moisturizing to act on, while also have antibacterial action, right
Spying on apparatus and vagina in gynemetrics all has splendid lubricant effect.
Above-mentioned lubricant uses organic anti-bacterial anti-corrosion material, and heat resistance is poor, and has certain toxicity, easily to skin
Skin causes to stimulate and allergy, and bacterium is produced drug resistance, makes a variation into superbacteria, harm to the human body is bigger on the contrary.Silver system
Although antiseptic, with excellent anti-microbial property, there is also drawback, outstanding behaviours is expensive at its for the use of Nano Silver,
Easily discoloration, silver ion separate out chromogenesis calmness, and silver ion easily adversely affects to environmental and human health impacts in addition.
The content of the invention
In order to solve the above technical problems, the present invention exists for existing antibiotic functional material particularly anti-bacterial lubricant field
Deficiency, there is provided a kind of safety and environmental protection, at the same have concurrently antibacterial lubricant effect and for effective antibacterial lubricant outside tapon
Agent prepares and application.The anti-bacterial lubricant is particularly suitable for the application on catheter type tapon outer tube, removes outer tube microorganism, carries
Its high lubricity, has extremely strong antibacterial functions, and to human body without any stimulation and allergy, safety and environmental protection；Especially as defending
Raw sliver outer tube lubricant, can be particularly suitable for itself efficiently against worry exceeded to tapon outer tube microorganism at present
Women with gynaecological imflammation uses in physiology phase, is advantageous to further genralrlization and the use of tapon.
To achieve the above object of the invention, the technical solution adopted by the present invention concrete technology flow process is as follows：
The first step, by the nano-metal-oxide with certain antibacterial action, a small amount of rare-earth mineral prime element and complexing agent
Uniformly mixed with certain proportion, form mixture；
Second step, said mixture is gradually added drop-wise in oleaginous system under stirring, forms stable Water-In-Oil
System；
3rd step, water-in-oil system is placed in 120-170 DEG C of heating response kettle and reacts 30-120min；
4th step, by reacted water-in-oil system carry out cooling treatment；
5th step, the water-in-oil system after cooling is centrifuged, removes precipitum, produce with antibacterial action
Lubricant.
In order to further optimize above-mentioned technical proposal, the nano-metal-oxide is the nano metal oxide of colorless and odorless
Thing, size have certain antibiotic property, mainly the oxidation including zinc, magnesium, calcium, titanium, aluminium, zirconium, barium, strontium between 10-100nm
One or more in thing.
In order to further optimize above-mentioned technical proposal, the rare-earth mineral prime element is soluble rare earth compound,
Effect is to carry out trace doped raising antibacterial activity to metal oxide, mainly including lanthanum, cerium, neodymium, bismuth LREE chemical combination
One or more in thing.
In order to further optimize above-mentioned technical proposal, the complexing agent is environmentally friendly polymer substance safe to the human body, bag
Include the one or more in cyclodextrin, amino acid, lecithin, chitin, polyvinylpyrrolidone, polypeptide；Effect is to mixing
Miscellaneous nano-metal-oxide carries out surface modification, improves its dispersion stabilization in oleaginous system.
In order to further optimize above-mentioned technical proposal, the oleaginous system is with lubrication, and safety and environmental protection is to skin
The material of the non-stimulated no allergy of skin, while nano material is effectively coated, the structure of similar microcapsules is formed, including it is poly-
Ethylene glycol 200, polyethylene glycol 400, Macrogol 600, the one or more in glycerine.
In order to further optimize above-mentioned technical proposal, the heating response kettle is oil bath pan, hydrothermal reaction kettle or micro-wave oven.
Pass through above-mentioned technical proposal, the present invention are used antibacterial metal oxide, a small amount of rare-earth mineral prime element and complexing
Agent is mixed with certain proportion, is gradually added drop-wise under agitation in oleaginous system, forms stable water-in-oil system；In 120-
30-120min is reacted in 170 DEG C of reactors, is cooled down, centrifuges, produces the lubricant with antibacterial action.With prior art
To compare, anti-bacterial lubricant provided by the invention has extremely strong antibacterial functions, and to human body without any stimulation and allergy, safety collar
Protect；, can be efficiently against load exceeded to tapon outer tube microorganism at present especially as tapon outer tube lubricant
The heart, it is particularly suitable for women with gynaecological imflammation itself and is used in physiology phase, be advantageous to the further genralrlization of tapon and make
With.
In summary, outstanding advantages of the invention are as follows：
1. anti-bacterial lubricant obtained by has extremely strong antibacterial functions, and to human body without any stimulation and allergy, safety
Environmental protection；
2. anti-bacterial lubricant obtained by is particularly suitable for the outer catheter of tapon, good with the affinity of tube material, carries
The lubricity of high conduit；
3. anti-bacterial lubricant obtained by is not present silver ion and separates out discoloration problem, ensure that the long-term effect of function, simultaneously
It is greatly broadened use range.
Brief description of the drawings
In order to illustrate more clearly about the embodiment of the present invention or technical scheme of the prior art, below will be to embodiment or existing
There is the required accompanying drawing used in technology description to be briefly described, it should be apparent that, drawings in the following description are only this
Some embodiments of invention, for those of ordinary skill in the art, on the premise of not paying creative work, can be with
Other accompanying drawings are obtained according to these accompanying drawings.
Fig. 1 is that effective anti-bacterial lubricant is used in the design sketch before Escherichia coli antibacterial outside a kind of tapon of the present invention；
Fig. 2 is that effective anti-bacterial lubricant is used in the design sketch after Escherichia coli antibacterial outside a kind of tapon of the present invention；
Fig. 3 is that effective anti-bacterial lubricant is used in the effect before Staphylococcus aureus antibacterial outside a kind of tapon of the present invention
Figure；
Fig. 4 is that effective anti-bacterial lubricant is used in the effect after Staphylococcus aureus antibacterial outside a kind of tapon of the present invention
Figure；
Fig. 5 is the transmission electron microscope picture of the anti-bacterial lubricant of the embodiment of the present invention 1.
Embodiment
Below in conjunction with the accompanying drawing in the embodiment of the present invention, the technical scheme in the embodiment of the present invention is carried out clear, complete
Site preparation describes, it is clear that described embodiment is only part of the embodiment of the present invention, rather than whole embodiments.It is based on
Embodiment in the present invention, those of ordinary skill in the art are obtained every other under the premise of creative work is not made
Embodiment, belong to the scope of protection of the invention.
With reference to embodiment and embodiment, the present invention is further detailed explanation.
Embodiment 1：
The preparation and application of effective anti-bacterial lubricant outside a kind of tapon, by nano zine oxide, nano-titanium oxide, nitric acid
Cerium, polyvinylpyrrolidone are according to 1：0.5：0.01：2.5 mol ratios are dispersed in water the aqueous dispersions A for being configured to 0.01M；Will
20 milliliters of water solution As are gradually added drop-wise under stirring in 100 milliliters of glycerine B, obtain the homogeneous system of Water-In-Oil；
30min is reacted in hydrothermal reaction kettle at 150 DEG C, is cooled down, is centrifuged, removes bottom precipitum, clear liquid is anti-bacterial lubricant.
Referring to the antibiogram of accompanying drawing 1, accompanying drawing 2, accompanying drawing 3 and accompanying drawing 4, resist made from the processing method as described in the present embodiment
Bacterium lubricant has excellent anti-microbial property.Fig. 5 is the transmission electron microscope picture of the present embodiment anti-bacterial lubricant, as described in the present embodiment
Processing method made from dispersed the metal oxide of cluster-shaped in anti-bacterial lubricant, form the metal oxide of cluster
Size about 20nm or so.
Embodiment 2：
Referring to accompanying drawing 2, the preparation and application of effective anti-bacterial lubricant outside a kind of tapon, by nano zine oxide, nanometer
Titanium oxide, cerous nitrate, cyclodextrin are according to 1：0.5：0.01：3.5 mol ratios are dispersed in water the aqueous dispersions A for being configured to 0.02M；
10 milliliters of water solution As are gradually added drop-wise to the Water-In-Oil body stablized in 100 milliliters of polyethylene glycol 400 B under stirring
System；It is put into micro-wave oven, 20min is reacted at 150 DEG C, cool down, centrifuge, removes bottom precipitum, clear liquid is antibacterial
Lubricant.
Referring to the antibiogram of accompanying drawing 1, accompanying drawing 2, accompanying drawing 3 and accompanying drawing 4, resist made from the processing method as described in the present embodiment
Bacterium lubricant has excellent anti-microbial property.Fig. 5 is the transmission electron microscope picture of the present embodiment anti-bacterial lubricant, as described in the present embodiment
Processing method made from dispersed the metal oxide of cluster-shaped in anti-bacterial lubricant, form the metal oxide of cluster
Size about 20nm or so.
Embodiment 3：
The preparation and application of effective anti-bacterial lubricant outside a kind of tapon, by nano zine oxide, nano magnesia, nitric acid
Neodymium, lecithin are according to 1：0.5：0.01：3.5 mol ratios are dispersed in water the aqueous dispersions A for being configured to 0.05M；By 10 milliliters of water
Solution A is gradually added drop-wise in 100 milliliters of polyethylene glycol 200 B under stirring and obtains water-in-oil system；It is put into micro-wave oven,
30min is reacted at 140 DEG C, is cooled down, is centrifuged, removes bottom precipitum, clear liquid is anti-bacterial lubricant.
Referring to the antibiogram of accompanying drawing 1, accompanying drawing 2, accompanying drawing 3 and accompanying drawing 4, resist made from the processing method as described in the present embodiment
Bacterium lubricant has excellent anti-microbial property.Fig. 5 is the transmission electron microscope picture of the present embodiment anti-bacterial lubricant, as described in the present embodiment
Processing method made from dispersed the metal oxide of cluster-shaped in anti-bacterial lubricant, form the metal oxide of cluster
Size about 20nm or so.
It is an object of the invention to explore a kind of preparation of anti-bacterial lubricant and answering on catheter type tapon outer tube
With overcoming existing for existing anti-bacterial lubricant insufficient.By antibacterial metal oxide, a small amount of rare-earth mineral prime element and complexing agent with
Certain proportion mixes, and is gradually added drop-wise in stirring condition in oleaginous system, forms stable water-in-oil system；At 120-170 DEG C
20-90min is reacted in reactor, is cooled down, is centrifuged and produce the lubricant with antibacterial action.The antibacterial metal oxide
For the nano-metal-oxide of colorless and odorless, size is within 10-100nm, mainly including zinc, magnesium, calcium, titanium, aluminium, zirconium, barium, strontium
Compound in one or more：The rare earth mineral is soluble rare earth compound, and effect is that metal is aoxidized
Thing carries out trace doped raising antibacterial activity, mainly including the one or more in lanthanum, cerium, neodymium, bismuth LREE compound；
The complexing agent is the polymer substance of safety and environmental protection, including cyclodextrin, amino acid, lecithin, chitin, polyvinylpyrrolidine
One or more in ketone, polypeptide：The oleaginous system is with lubrication, and the thing that safety and environmental protection is non-stimulated to skin
One or more in matter, including polyethylene glycol 200, polyethylene glycol 400, Macrogol 600, glycerine etc.：The reactor
Can be oil bath pan, hydrothermal reaction kettle, micro-wave oven etc..Resulting anti-bacterial lubricant has extremely strong antibacterial functions, and to people
Body is without any stimulation, safety and environmental protection；, can be efficiently against at present to tapon especially as tapon outer tube lubricant
The exceeded worry of outer tube microorganism, it is particularly suitable for women with gynaecological imflammation itself and is used in physiology phase, be advantageous to cotton wool
The further genralrlization of bar and use.
Above-described is only that the preparation of effective anti-bacterial lubricant outside a kind of tapon of the invention and application are preferred real
Apply mode, it is noted that for the person of ordinary skill of the art, without departing from the concept of the premise of the invention,
Various modifications and improvements can be made, these belong to protection scope of the present invention.
Claims (6)
1. the preparation and application of effective anti-bacterial lubricant outside a kind of tapon, it is characterised in that including following preparation process：
The first step, by the nano-metal-oxide with certain antibacterial action, a small amount of rare-earth mineral prime element and complexing agent with one
Certainty ratio uniformly mixes, and forms mixture；
Second step, said mixture is gradually added drop-wise in oleaginous system under stirring, forms stable water-in-oil system；
3rd step, water-in-oil system is placed in 120-170 DEG C of heating response kettle and reacts 30-120min；
4th step, by reacted water-in-oil system carry out cooling treatment；
5th step, the water-in-oil system after cooling is centrifuged, removes precipitum, produce the lubrication with antibacterial action
Agent.
2. the preparation and application of effective anti-bacterial lubricant outside a kind of tapon according to claim 1, it is characterised in that
The nano-metal-oxide is the nano-metal-oxide of colorless and odorless, and size has certain resist between 10-100nm
Bacterium property, mainly including zinc, magnesium, calcium, titanium, aluminium, zirconium, barium, strontium oxide in one or more.
3. the preparation and application of effective anti-bacterial lubricant outside a kind of tapon according to claim 1, it is characterised in that
The rare-earth mineral prime element is soluble rare earth compound, and effect is to carry out trace doped improve to metal oxide to resist
Bacterium activity, mainly including the one or more in lanthanum, cerium, neodymium, bismuth LREE compound.
4. the preparation and application of effective anti-bacterial lubricant outside a kind of tapon according to claim 1, it is characterised in that
The complexing agent is environmentally friendly polymer substance safe to the human body, including cyclodextrin, amino acid, lecithin, chitin, polyethylene
One or more in pyrrolidones, polypeptide；Effect is the nano-metal-oxide progress surface modification to doping, improves it
Dispersion stabilization in oleaginous system.
5. the preparation and application of effective anti-bacterial lubricant outside a kind of tapon according to claim 1, it is characterised in that
The oleaginous system is and the material of safety and environmental protection no allergy non-stimulated to skin with lubrication, while to nano material
Effectively coated, the structure of the similar microcapsules of formation, including polyethylene glycol 200, polyethylene glycol 400, Macrogol 600,
One or more in glycerine.
6. the preparation and application of effective anti-bacterial lubricant outside a kind of tapon according to claim 1, it is characterised in that
The heating response kettle is oil bath pan, hydrothermal reaction kettle or micro-wave oven.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710979607.2A CN107693837B (en) | 2017-10-19 | 2017-10-19 | Preparation and application of antibacterial lubricant for tampon outer tube |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710979607.2A CN107693837B (en) | 2017-10-19 | 2017-10-19 | Preparation and application of antibacterial lubricant for tampon outer tube |
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| Publication Number | Publication Date |
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| CN107693837A true CN107693837A (en) | 2018-02-16 |
| CN107693837B CN107693837B (en) | 2020-12-29 |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109112838A (en) * | 2018-06-07 | 2019-01-01 | 苏州东展羽绒服饰有限公司 | A kind of preparation method of antibacterial deodorizing nano water-proof natural feather |
| CN118044947A (en) * | 2023-12-26 | 2024-05-17 | 优立美(湖北)科技有限公司 | Sanitary cotton sliver outer catheter frosted tube body and preparation method thereof |
| CN118490897A (en) * | 2024-05-15 | 2024-08-16 | 优立美(湖北)科技有限公司 | Antibacterial outer catheter for sanitary cotton sliver and preparation method thereof |
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